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Brent H. Koehn, Ph.D. - Publications

Affiliations: 
2007 Emory University, Atlanta, GA 
Area:
Immunology, Microbiology Biology
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Larson JH, Jin S, Loschi M, Wagers SB, Thangavelu G, Zaiken MC, McDonald-Hyman C, Saha A, Aguilar EG, Koehn B, Osborn MJ, Panoskaltsis-Mortari A, Macdonald KPA, Hill GR, Murphy WJ, et al. Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 36878433 DOI: 10.1016/j.ajt.2023.01.030  0.43
2022 Lopes Ramos T, Bolivar-Wagers S, Jin S, Thangavelu G, Simonetta F, Lin PY, Hirai T, Saha A, Koehn BH, L Su L, Picton LK, Baker J, Lohmeyer JK, Riddle MJ, Eide C, et al. Prevention of acute GVHD disease using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T-cells in vivo. Blood. PMID 36564052 DOI: 10.1182/blood.2022018440  0.403
2022 Bolivar-Wagers S, Loschi ML, Jin S, Thangavelu G, Larson JH, McDonald-Hyman CS, Aguilar EA, Saha A, Koehn BH, Hefazi M, Osborn MJ, Jensen MC, Wagner JE, Pennell CA, Blazar BR. Murine CAR19 Tregs suppress acute graft-versus-host disease and maintain graft-versus-tumor responses. Jci Insight. PMID 35917188 DOI: 10.1172/jci.insight.160674  0.518
2021 Walton K, Walker K, Riddle M, Koehn BH, Reff J, Sagatys EM, Linden MA, Pidala J, Kim J, Lee MC, Kiluk JV, Hui JYC, Yun SY, Xing Y, Stefanski H, et al. Dual JAK2/Aurora kinase A inhibition prevents human skin graft rejection by allo-inactivation and ILC2-mediated tissue repair. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 34668635 DOI: 10.1111/ajt.16870  0.388
2020 ElTanbouly MA, Zhao Y, Nowak E, Li J, Schaafsma E, Le Mercier I, Ceeraz S, Lines JL, Peng C, Carriere C, Huang X, Day M, Koehn B, Lee SW, Silva Morales M, et al. VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance. Science (New York, N.Y.). 367. PMID 31949051 DOI: 10.1126/Science.Aay0524  0.454
2019 Koehn BH, Saha A, McDonald-Hyman C, Loschi M, Thangavelu G, Ma L, Zaiken M, Dysthe J, Krepps W, Panthera J, Hippen K, Jameson SC, Miller JS, Cooper MA, Farady CJ, et al. Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GvHD. Blood. PMID 31533918 DOI: 10.1182/Blood.2019001950  0.405
2019 Thangavelu G, Lee YC, Loschi M, Schaechter KM, Feser CJ, Koehn BH, Nowak EC, Zeiser R, Serody JS, Murphy WJ, Munn DH, Chambon P, Noelle RJ, Blazar BR. Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality. Journal of Immunology (Baltimore, Md. : 1950). PMID 30885956 DOI: 10.4049/Jimmunol.1800899  0.487
2018 McDonald-Hyman C, Muller JT, Loschi M, Thangavelu G, Saha A, Kumari S, Reichenbach DK, Smith MJ, Zhang G, Koehn BH, Lin J, Mitchell JS, Fife BT, Panoskaltsis-Mortari A, Feser CJ, et al. The vimentin intermediate filament network restrains regulatory T-cell suppression of graft-versus-host disease. The Journal of Clinical Investigation. PMID 30106752 DOI: 10.1172/Jci95713  0.506
2018 Sharma MD, Rodriguez PC, Koehn BH, Baban B, Cui Y, Guo G, Shimoda M, Pacholczyk R, Shi H, Lee EJ, Xu H, Johnson TS, He Y, Mergoub T, Venable C, et al. Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors. Immunity. 48: 91-106.e6. PMID 29343444 DOI: 10.1016/J.Immuni.2017.12.014  0.503
2017 Koehn BH, Blazar BR. Role of myeloid-derived suppressor cells in allogeneic hematopoietic cell transplantation. Journal of Leukocyte Biology. PMID 28148718 DOI: 10.1189/Jlb.5Mr1116-464R  0.518
2016 Matta BM, Reichenbach DK, Zhang X, Mathews L, Koehn BH, Dwyer GK, Lott JM, Uhl FM, Pfeifer D, Feser CJ, Smith MJ, Liu Q, Zeiser R, Blazar BR, Turnquist HR. Peri-alloHCT IL-33 administration expands recipient T regulatory cells that protect mice against acute GVHD. Blood. PMID 27222477 DOI: 10.1182/Blood-2015-12-684142  0.416
2015 Koehn BH, Zeiser R, Blazar BR. Inflammasome effects in GvHD. Oncotarget. 6: 38444-5. PMID 26564963 DOI: 10.18632/Oncotarget.6307  0.517
2015 Koehn BH, Apostolova P, Haverkamp JM, Miller JS, McCullar V, Tolar J, Munn DH, Murphy WJ, Brickey WJ, Serody JS, Gabrilovich DI, Bronte V, Murray PJ, Ting JP, Zeiser R, et al. GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells. Blood. 126: 1621-8. PMID 26265697 DOI: 10.1182/Blood-2015-03-634691  0.481
2015 Reichenbach DK, Schwarze V, Matta BM, Tkachev V, Lieberknecht E, Liu Q, Koehn BH, Pfeifer D, Taylor PA, Prinz G, Dierbach H, Stickel N, Beck Y, Warncke M, Junt T, et al. The IL-33/ST2 axis augments effector T-cell responses during acute GVHD. Blood. 125: 3183-92. PMID 25814531 DOI: 10.1182/Blood-2014-10-606830  0.453
2015 McDonald-Hyman C, Thangavelu G, Muller J, Zhang G, Kumari S, Saha A, Koehn BH, Mitchell JS, Fife BT, Serody JS, Osborn MJ, Hippen KL, Kelekar A, Munn DH, Altman A, et al. Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function Blood. 126: 849-849. DOI: 10.1182/Blood.V126.23.849.849  0.471
2014 Monjazeb AM, Tietze JK, Grossenbacher SK, Hsiao HH, Zamora AE, Mirsoian A, Koehn B, Blazar BR, Weiss JM, Wiltrout RH, Sckisel GD, Murphy WJ. Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help. Plos One. 9: e102709. PMID 25119341 DOI: 10.1371/Journal.Pone.0102709  0.563
2014 Reichenbach DK, Schwarze V, Matta BM, Tkachev V, Lieberknecht E, Liu Q, Koehn BH, Pfeifer D, Taylor PA, Prinz G, Dierbach H, Stickel N, Beck Y, Warncke M, Junt T, et al. Regulation of Immune Responses during Acute GvHD Via the IL-33/ST2 Axis Blood. 124: 844-844. DOI: 10.1182/Blood.V124.21.844.844  0.444
2013 Saha A, Aoyama K, Taylor PA, Koehn BH, Veenstra RG, Panoskaltsis-Mortari A, Munn DH, Murphy WJ, Azuma M, Yagita H, Fife BT, Sayegh MH, Najafian N, Socie G, Ahmed R, et al. Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality. Blood. 122: 3062-73. PMID 24030385 DOI: 10.1182/Blood-2013-05-500801  0.401
2013 Grossenbacher SK, Monjazeb AM, Tietze J, Sckisel GD, Mirsoian A, Hsiao H, Koehn B, Wilkins D, Blazer BR, Murphy WJ. Bystander memory CD8 T cell proliferation after anti-CD40/IL-2 treatment is independent of CD4 T cells Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P100  0.558
2012 Ferrer IR, Liu D, Pinelli DF, Koehn BH, Stempora LL, Ford ML. CD40/CD154 blockade inhibits dendritic cell expression of inflammatory cytokines but not costimulatory molecules. Journal of Immunology (Baltimore, Md. : 1950). 189: 4387-95. PMID 23002440 DOI: 10.4049/Jimmunol.1201757  0.705
2011 Floyd TL, Koehn BH, Kitchens WH, Robertson JM, Cheeseman JA, Stempora L, Larsen CP, Ford ML. Limiting the amount and duration of antigen exposure during priming increases memory T cell requirement for costimulation during recall. Journal of Immunology (Baltimore, Md. : 1950). 186: 2033-41. PMID 21257960 DOI: 10.4049/Jimmunol.1003015  0.653
2010 Highfill SL, Rodriguez PC, Zhou Q, Goetz CA, Koehn BH, Veenstra R, Taylor PA, Panoskaltsis-Mortari A, Serody JS, Munn DH, Tolar J, Ochoa AC, Blazar BR. Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13. Blood. 116: 5738-47. PMID 20807889 DOI: 10.1182/Blood-2010-06-287839  0.44
2009 Koehn BH, Schoenberger SP. Tumor immunotherapy: making an immortal army. Nature Medicine. 15: 731-2. PMID 19584859 DOI: 10.1038/Nm0709-731  0.373
2008 Koehn BH, Ford ML, Ferrer IR, Borom K, Gangappa S, Kirk AD, Larsen CP. PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+ T cells to transplanted tissue. Journal of Immunology (Baltimore, Md. : 1950). 181: 5313-22. PMID 18832687 DOI: 10.4049/Jimmunol.181.8.5313  0.687
2007 Koehn BH, Williams MA, Borom K, Gangappa S, Pearson TC, Ahmed R, Larsen CP. Fully MHC-disparate mixed hemopoietic chimeras show specific defects in the control of chronic viral infections. Journal of Immunology (Baltimore, Md. : 1950). 179: 2616-26. PMID 17675525 DOI: 10.4049/Jimmunol.179.4.2616  0.61
2007 Ford ML, Koehn BH, Wagener ME, Jiang W, Gangappa S, Pearson TC, Larsen CP. Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation. The Journal of Experimental Medicine. 204: 299-309. PMID 17261633 DOI: 10.1084/Jem.20062319  0.674
2006 Koehn B, Gangappa S, Miller JD, Ahmed R, Larsen CP. Patients, pathogens, and protective immunity: the relevance of virus-induced alloreactivity in transplantation. Journal of Immunology (Baltimore, Md. : 1950). 176: 2691-6. PMID 16493023 DOI: 10.4049/Jimmunol.176.5.2691  0.585
2006 Kean LS, Hamby K, Koehn B, Lee E, Coley S, Stempora L, Adams AB, Heiss E, Pearson TC, Larsen CP. NK cells mediate costimulation blockade-resistant rejection of allogeneic stem cells during nonmyeloablative transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 6: 292-304. PMID 16426313 DOI: 10.1111/J.1600-6143.2005.01172.X  0.709
2006 Ford M, Koehn B, Wagener M, Borom K, Gangappa S, Pearson T, Larsen C. F.142. Inhibition of T-Cell Activation By CD28 and CD40L Blockade Is Influenced By T-Cell Precursor Frequency Clinical Immunology. 119: S100-S101. DOI: 10.1016/J.Clim.2006.04.182  0.614
2006 Koehn B, Borom K, Gangappa S, Pearson T, Larsen C. F.141. A Role for PD-1 in Maintaining Peripheral Tolerance to An Allogeneic Skin Graft Clinical Immunology. 119: S100. DOI: 10.1016/J.Clim.2006.04.181  0.529
2002 McGargill MA, Mayerova D, Stefanski HE, Koehn B, Parke EA, Jameson SC, Panoskaltsis-Mortari A, Hogquist KA. A spontaneous CD8 T cell-dependent autoimmune disease to an antigen expressed under the human keratin 14 promoter. Journal of Immunology (Baltimore, Md. : 1950). 169: 2141-7. PMID 12165543 DOI: 10.4049/Jimmunol.169.4.2141  0.425
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