Year |
Citation |
Score |
2023 |
Qiu Y. A phosphorylation switch controls androgen biosynthesis in prostate cancer. The Journal of Clinical Investigation. 133. PMID 36647834 DOI: 10.1172/JCI166499 |
0.52 |
|
2022 |
Alfano A, Xu J, Yang X, Deshmukh D, Qiu Y. SRC Kinase-Mediated Tyrosine Phosphorylation of TUBB3 Regulates Its Stability and Mitotic Spindle Dynamics in Prostate Cancer Cells. Pharmaceutics. 14. PMID 35631517 DOI: 10.3390/pharmaceutics14050932 |
0.447 |
|
2022 |
Deshmukh D, Xu J, Yang X, Shimelis H, Fang S, Qiu Y. Regulation of p27 (Kip1) by Ubiquitin E3 Ligase RNF6. Pharmaceutics. 14. PMID 35456636 DOI: 10.3390/pharmaceutics14040802 |
0.615 |
|
2020 |
Xu J, Yang X, Deshmukh D, Chen H, Fang S, Qiu Y. The Role of Crosstalk between AR3 and E2F1 in Drug Resistance in Prostate Cancer Cells. Cells. 9. PMID 32354165 DOI: 10.3390/Cells9051094 |
0.525 |
|
2019 |
Kwegyir-Afful AK, Ramalingam S, Ramamurthy VP, Purushottamachar P, Murigi FN, Vasaitis TS, Huang W, Kane MA, Zhang Y, Ambulos N, Tiwari S, Srivastava P, Nnane IP, Hussain A, Qiu Y, et al. Galeterone and The Next Generation Galeterone Analogs, VNPP414 and VNPP433-3β Exert Potent Therapeutic Effects in Castration-/Drug-Resistant Prostate Cancer Preclinical Models In Vitro and In Vivo. Cancers. 11. PMID 31653008 DOI: 10.3390/Cancers11111637 |
0.522 |
|
2019 |
Xu J, Qiu Y. Current opinion and mechanistic interpretation of combination therapy for castration-resistant prostate cancer. Asian Journal of Andrology. PMID 30924449 DOI: 10.4103/aja.aja_10_19 |
0.355 |
|
2016 |
Xu J, Qiu Y. Role of androgen receptor splice variants in prostate cancer metastasis. Asian Journal of Urology. 3: 177-184. PMID 28239558 DOI: 10.1016/j.ajur.2016.08.003 |
0.512 |
|
2015 |
Deshmukh D, Qiu Y. Role of PARP-1 in prostate cancer. American Journal of Clinical and Experimental Urology. 3: 1-12. PMID 26069882 |
0.421 |
|
2014 |
Sun F, Chen HG, Li W, Yang X, Wang X, Jiang R, Guo Z, Chen H, Huang J, Borowsky AD, Qiu Y. Androgen receptor splice variant AR3 promotes prostate cancer via modulating expression of autocrine/paracrine factors. The Journal of Biological Chemistry. 289: 1529-39. PMID 24297183 DOI: 10.1074/Jbc.M113.492140 |
0.568 |
|
2014 |
Qiu Y, Sun F, Yang X. Abstract LB-26: Androgen receptor splice variant AR3 promotes prostate cancer via modulating expression of autocrine/paracrine factors Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-26 |
0.573 |
|
2013 |
Natarajan K, Xie Y, Burcu M, Linn DE, Qiu Y, Baer MR. Pim-1 kinase phosphorylates and stabilizes 130 kDa FLT3 and promotes aberrant STAT5 signaling in acute myeloid leukemia with FLT3 internal tandem duplication. Plos One. 8: e74653. PMID 24040307 DOI: 10.1371/Journal.Pone.0074653 |
0.706 |
|
2013 |
Linn D, Yang X, Xie Y, Alfano A, Deshmukh D, Wang X, Shimelis H, Chen H, Li W, Xu K, Chen M, Qiu Y. Abstract 4089: Differential regulation of androgen receptor by PIM-1 kinases via phosphorylation-dependent recruitment of distinct ubiquitin E3 ligases. Cancer Research. 73: 4089-4089. DOI: 10.1158/1538-7445.Am2013-4089 |
0.801 |
|
2012 |
Linn DE, Yang X, Xie Y, Alfano A, Deshmukh D, Wang X, Shimelis H, Chen H, Li W, Xu K, Chen M, Qiu Y. Differential regulation of androgen receptor by PIM-1 kinases via phosphorylation-dependent recruitment of distinct ubiquitin E3 ligases. The Journal of Biological Chemistry. 287: 22959-68. PMID 22584579 DOI: 10.1074/Jbc.M111.338350 |
0.802 |
|
2011 |
Yang X, Guo Z, Sun F, Li W, Alfano A, Shimelis H, Chen M, Brodie AM, Chen H, Xiao Z, Veenstra TD, Qiu Y. Novel membrane-associated androgen receptor splice variant potentiates proliferative and survival responses in prostate cancer cells. The Journal of Biological Chemistry. 286: 36152-60. PMID 21878636 DOI: 10.1074/Jbc.M111.265124 |
0.75 |
|
2011 |
Guo Z, Qiu Y. A new trick of an old molecule: androgen receptor splice variants taking the stage?! International Journal of Biological Sciences. 7: 815-22. PMID 21750650 |
0.476 |
|
2011 |
Guo S, Sun F, Guo Z, Li W, Alfano A, Chen H, Magyar CE, Huang J, Chai TC, Qiu S, Qiu Y. Tyrosine kinase ETK/BMX is up-regulated in bladder cancer and predicts poor prognosis in patients with cystectomy. Plos One. 6: e17778. PMID 21408190 DOI: 10.1371/Journal.Pone.0017778 |
0.464 |
|
2010 |
Linn DE, Yang X, Sun F, Xie Y, Chen H, Jiang R, Chen H, Chumsri S, Burger AM, Qiu Y. A Role for OCT4 in Tumor Initiation of Drug-Resistant Prostate Cancer Cells. Genes & Cancer. 1: 908-16. PMID 21779471 DOI: 10.1177/1947601910388271 |
0.716 |
|
2010 |
Dai B, Chen H, Guo S, Yang X, Linn DE, Sun F, Li W, Guo Z, Xu K, Kim O, Kong X, Melamed J, Qiu S, Chen H, Qiu Y. Compensatory upregulation of tyrosine kinase Etk/BMX in response to androgen deprivation promotes castration-resistant growth of prostate cancer cells. Cancer Research. 70: 5587-96. PMID 20570899 DOI: 10.1158/0008-5472.Can-09-4610 |
0.789 |
|
2010 |
Cohen I, Maoz M, Turm H, Grisaru-Granovsky S, Maly B, Uziely B, Weiss E, Abramovitch R, Gross E, Barzilay O, Qiu Y, Bar-Shavit R. Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significance. Plos One. 5: e11135. PMID 20559570 DOI: 10.1371/Journal.Pone.0011135 |
0.369 |
|
2010 |
Xie Y, Burcu M, Linn DE, Qiu Y, Baer MR. Pim-1 kinase protects P-glycoprotein from degradation and enables its glycosylation and cell surface expression. Molecular Pharmacology. 78: 310-8. PMID 20460432 DOI: 10.1124/Mol.109.061713 |
0.724 |
|
2010 |
Linn DE, Yang X, Sun F, Xie Y, Chumsri S, Burger A, Qiu Y. Abstract 4228: A functional role of OCT4 for prostate tumor initiation Cancer Research. 70: 4228-4228. DOI: 10.1158/1538-7445.Am10-4228 |
0.732 |
|
2010 |
Guo Z, Yang X, Sun F, Linn DE, Jiang R, Chen H, Chen H, Kong X, Melamed J, Tepper CG, Kung H, Brodie AMH, Edwards J, Qiu Y. Abstract 1712: Androgen receptor splicing variants promote therapeutic resistance in prostate cancer Cancer Research. 70: 1712-1712. DOI: 10.1158/1538-7445.Am10-1712 |
0.779 |
|
2010 |
Baer MR, Xie Y, Burcu M, Qiu Y. Abstract 1529: Pim-1 kinase protects P-glycoprotein from degradation and enables its glycosylation and cell surface expression Cancer Research. 70: 1529-1529. DOI: 10.1158/1538-7445.Am10-1529 |
0.515 |
|
2009 |
Xu K, Shimelis H, Linn DE, Jiang R, Yang X, Sun F, Guo Z, Chen H, Li W, Chen H, Kong X, Melamed J, Fang S, Xiao Z, Veenstra TD, ... Qiu Y, et al. Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination. Cancer Cell. 15: 270-82. PMID 19345326 DOI: 10.1016/J.Ccr.2009.02.021 |
0.788 |
|
2009 |
Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, Chen H, Kong X, Melamed J, Tepper CG, Kung HJ, Brodie AM, Edwards J, Qiu Y. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Research. 69: 2305-13. PMID 19244107 DOI: 10.1158/0008-5472.Can-08-3795 |
0.774 |
|
2009 |
Chiu YT, Han HY, Leung SC, Yuen HF, Chau CW, Guo Z, Qiu Y, Chan KW, Wang X, Wong YC, Ling MT. CDC25A functions as a novel Ar corepressor in prostate cancer cells. Journal of Molecular Biology. 385: 446-56. PMID 19013180 DOI: 10.1016/j.jmb.2008.10.070 |
0.526 |
|
2008 |
Xie Y, Xu K, Linn DE, Yang X, Guo Z, Shimelis H, Nakanishi T, Ross DD, Chen H, Fazli L, Gleave ME, Qiu Y. The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells. The Journal of Biological Chemistry. 283: 3349-56. PMID 18056989 DOI: 10.1074/Jbc.M707773200 |
0.785 |
|
2007 |
Nair SS, Guo Z, Mueller JM, Koochekpour S, Qiu Y, Tekmal RR, Schüle R, Kung HJ, Kumar R, Vadlamudi RK. Proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only protein 2. Molecular Endocrinology (Baltimore, Md.). 21: 613-24. PMID 17192406 DOI: 10.1210/Me.2006-0269 |
0.539 |
|
2007 |
Guo Z, Dai B, Jiang T, Xu K, Xie Y, Kim O, Nesheiwat I, Kong X, Melamed J, Handratta VD, Njar VCO, Brodie AMH, Yu LR, Veenstra TD, Chen H, ... Qiu Y, et al. Regulation of Androgen Receptor Activity by Tyrosine Phosphorylation (DOI:10.1016/j.ccr.2006.08.021) Cancer Cell. 11. DOI: 10.1016/J.Ccr.2006.12.010 |
0.442 |
|
2006 |
Guo Z, Dai B, Jiang T, Xu K, Xie Y, Kim O, Nesheiwat I, Kong X, Melamed J, Handratta VD, Njar VC, Brodie AM, Yu LR, Veenstra TD, Chen H, ... Qiu Y, et al. Regulation of androgen receptor activity by tyrosine phosphorylation. Cancer Cell. 10: 309-19. PMID 17045208 DOI: 10.1016/J.Ccr.2006.08.021 |
0.588 |
|
2006 |
Dai B, Kim O, Xie Y, Guo Z, Xu K, Wang B, Kong X, Melamed J, Chen H, Bieberich CJ, Borowsky AD, Kung HJ, Wei G, Ostrowski MC, Brodie A, ... Qiu Y, et al. Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse. Cancer Research. 66: 8058-64. PMID 16912182 DOI: 10.1158/0008-5472.Can-06-1364 |
0.585 |
|
2006 |
Macedo LF, Guo Z, Tilghman SL, Sabnis GJ, Qiu Y, Brodie A. Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole. Cancer Research. 66: 7775-82. PMID 16885381 DOI: 10.1158/0008-5472.Can-05-3984 |
0.455 |
|
2006 |
Yang H, Wen YY, Zhao R, Lin YL, Fournier K, Yang HY, Qiu Y, Diaz J, Laronga C, Lee MH. DNA damage-induced protein 14-3-3 sigma inhibits protein kinase B/Akt activation and suppresses Akt-activated cancer. Cancer Research. 66: 3096-105. PMID 16540659 DOI: 10.1158/0008-5472.Can-05-3620 |
0.446 |
|
2006 |
Xie Y, Xu K, Dai B, Guo Z, Jiang T, Chen H, Qiu Y. The 44 kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugs. Oncogene. 25: 70-8. PMID 16186805 DOI: 10.1038/Sj.Onc.1209058 |
0.623 |
|
2005 |
Handratta VD, Vasaitis TS, Njar VC, Gediya LK, Kataria R, Chopra P, Newman D, Farquhar R, Guo Z, Qiu Y, Brodie AM. Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model. Journal of Medicinal Chemistry. 48: 2972-84. PMID 15828836 DOI: 10.1021/Jm040202W |
0.436 |
|
2005 |
Chau CH, Clavijo CA, Deng HT, Zhang Q, Kim KJ, Qiu Y, Le AD, Ann DK. Etk/Bmx mediates expression of stress-induced adaptive genes VEGF, PAI-1, and iNOS via multiple signaling cascades in different cell systems. American Journal of Physiology. Cell Physiology. 289: C444-54. PMID 15788485 DOI: 10.1152/Ajpcell.00410.2004 |
0.339 |
|
2004 |
Jiang T, Guo Z, Dai B, Kang M, Ann DK, Kung HJ, Qiu Y. Bi-directional regulation between tyrosine kinase Etk/BMX and tumor suppressor p53 in response to DNA damage. The Journal of Biological Chemistry. 279: 50181-9. PMID 15355990 DOI: 10.1074/Jbc.M409108200 |
0.492 |
|
2004 |
Kim O, Jiang T, Xie Y, Guo Z, Chen H, Qiu Y. Synergism of cytoplasmic kinases in IL6-induced ligand-independent activation of androgen receptor in prostate cancer cells. Oncogene. 23: 1838-44. PMID 14981536 DOI: 10.1038/Sj.Onc.1207304 |
0.549 |
|
2003 |
Jiang T, Qiu Y. Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation. The Journal of Biological Chemistry. 278: 15789-93. PMID 12600984 DOI: 10.1074/Jbc.M212525200 |
0.412 |
|
2002 |
Xia L, Robinson D, Ma AH, Chen HC, Wu F, Qiu Y, Kung HJ. Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells. The Journal of Biological Chemistry. 277: 35422-33. PMID 12084720 DOI: 10.1074/Jbc.M203940200 |
0.525 |
|
2002 |
Kim O, Yang J, Qiu Y. Selective activation of small GTPase RhoA by tyrosine kinase Etk through its pleckstrin homology domain. The Journal of Biological Chemistry. 277: 30066-71. PMID 12023958 DOI: 10.1074/Jbc.M201713200 |
0.4 |
|
2001 |
Chen R, Kim O, Yang J, Sato K, Eisenmann KM, McCarthy J, Chen H, Qiu Y. Regulation of Akt/PKB Activation by Tyrosine Phosphorylation Journal of Biological Chemistry. 276: 31858-31862. PMID 11445557 DOI: 10.1074/Jbc.C100271200 |
0.422 |
|
2001 |
Chen R, Kim O, Li M, Xiong X, Guan JL, Kung HJ, Chen H, Shimizu Y, Qiu Y. Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain. Nature Cell Biology. 3: 439-44. PMID 11331870 DOI: 10.1038/35074500 |
0.4 |
|
2001 |
Woods ML, Kivens WJ, Adelsman MA, Qiu Y, August A, Shimizu Y. A novel function for the Tec family tyrosine kinase Itk in activation of beta 1 integrins by the T-cell receptor. The Embo Journal. 20: 1232-44. PMID 11250890 DOI: 10.1093/Emboj/20.6.1232 |
0.344 |
|
2001 |
Qiu Y, Kung HJ. Signaling network of the Btk family kinases. Oncogene. 19: 5651-61. PMID 11114746 DOI: 10.1038/Sj.Onc.1203958 |
0.389 |
|
2000 |
Tsai YT, Su YH, Fang SS, Huang TN, Qiu Y, Jou YS, Shih HM, Kung HJ, Chen RH. Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking src to STAT3 activation Molecular and Cellular Biology. 20: 2043-2054. PMID 10688651 DOI: 10.1128/Mcb.20.6.2043-2054.2000 |
0.416 |
|
1999 |
Xue LY, Qiu Y, He J, Kung HJ, Oleinick NL. Etk/Bmx, a PH-domain containing tyrosine kinase, protects prostate cancer cells from apoptosis induced by photodynamic therapy or thapsigargin. Oncogene. 18: 3391-8. PMID 10362360 DOI: 10.1038/sj.onc.1202687 |
0.452 |
|
1998 |
Qiu Y, Ravi L, Kung HJ. Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells. Nature. 393: 83-5. PMID 9590694 DOI: 10.1038/30012 |
0.32 |
|
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