Year |
Citation |
Score |
2024 |
Ryan TE, Torres MJ, Lin CT, Clark AH, Brophy PM, Smith CA, Smith CD, Morris EM, Thyfault JP, Neufer PD. High-dose atorvastatin therapy progressively decreases skeletal muscle mitochondrial respiratory capacity in humans. Jci Insight. 9. PMID 38385748 DOI: 10.1172/jci.insight.174125 |
0.63 |
|
2023 |
Pal A, Lin CT, Boykov I, Benson E, Kidd G, Fisher-Wellman KH, Neufer PD, Shaikh SR. High Fat Diet-Induced Obesity Dysregulates Splenic B Cell Mitochondrial Activity. Nutrients. 15. PMID 38004202 DOI: 10.3390/nu15224807 |
0.722 |
|
2023 |
Fisher-Wellman KH, Kassai M, Hagen JT, Neufer PD, Kester M, Loughran TP, Chalfant CE, Feith DJ, Tan SF, Fox TE, Ung J, Fabrias G, Abad JL, Sharma A, Golla U, et al. Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia. Cancers. 15. PMID 36980769 DOI: 10.3390/cancers15061883 |
0.589 |
|
2023 |
Matthews CEP, Fussner LA, Yaeger M, Aloor JJ, Reece SW, Kilburg-Basnyat BJ, Varikuti S, Luo B, Inks M, Sergin S, Schmidt CA, Neufer PD, Pennington ER, Fisher-Wellman KH, Chowdhury SM, et al. The prohibitin complex regulates macrophage fatty acid composition, plasma membrane packing, and lipid raft-mediated inflammatory signaling. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 190: 102540. PMID 36706677 DOI: 10.1016/j.plefa.2023.102540 |
0.539 |
|
2022 |
Hagen JT, Montgomery MM, Biagioni EM, Krassovskaia P, Jevtovic F, Shookster D, Sharma U, Tung K, Broskey NT, May L, Huang H, Brault JJ, Neufer PD, Cabot MC, Fisher-Wellman KH. Intrinsic adaptations in OXPHOS power output and reduced tumorigenicity characterize doxorubicin resistant ovarian cancer cells. Biochimica Et Biophysica Acta. Bioenergetics. 1863: 148915. PMID 36058252 DOI: 10.1016/j.bbabio.2022.148915 |
0.636 |
|
2022 |
Tang Y, Zong H, Kwon H, Qiu Y, Pessin JB, Wu L, Buddo KA, Boykov I, Schmidt CA, Lin CT, Neufer PD, Schwartz GJ, Kurland IJ, Pessin J. TIGAR deficiency enhances skeletal muscle thermogenesis by increasing neuromuscular junction cholinergic signaling. Elife. 11. PMID 35254259 DOI: 10.7554/eLife.73360 |
0.552 |
|
2022 |
Pereyra AS, Lin CT, Sanchez DM, Laskin J, Spangenburg EE, Neufer PD, Fisher-Wellman K, Ellis JM. Skeletal muscle undergoes fiber type metabolic switch without myosin heavy chain switch in response to defective fatty acid oxidation. Molecular Metabolism. 101456. PMID 35150906 DOI: 10.1016/j.molmet.2022.101456 |
0.729 |
|
2022 |
Junker A, Wang J, Gouspillou G, Ehinger JK, Elmér E, Sjövall F, Fisher-Wellman KH, Neufer PD, Molina AJA, Ferrucci L, Picard M. Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences: A multivariate meta-analysis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 36: e22146. PMID 35073429 DOI: 10.1096/fj.202101628R |
0.627 |
|
2021 |
Schmidt CA, Fisher-Wellman KH, Neufer PD. From OCR and ECAR to energy: perspectives on the design and interpretation of bioenergetics studies. The Journal of Biological Chemistry. 101140. PMID 34461088 DOI: 10.1016/j.jbc.2021.101140 |
0.583 |
|
2021 |
Nelson MA, McLaughlin KL, Hagen JT, Coalson HS, Schmidt C, Kassai M, Kew KA, McClung JM, Neufer PD, Brophy P, Vohra NA, Liles D, Cabot MC, Fisher-Wellman KH. Intrinsic OXPHOS limitations underlie cellular bioenergetics in leukemia. Elife. 10. PMID 34132194 DOI: 10.7554/eLife.63104 |
0.625 |
|
2021 |
Smith CD, Schmidt CA, Fisher-Wellman KH, Neufer PD. Reply to Figueira et al.: Can NAD(P) transhydrogenase (NNT) mediate a physiologically meaningful increase in energy expenditure by mitochondria during HO removal? The Journal of Biological Chemistry. 296: 100378. PMID 33837732 DOI: 10.1016/j.jbc.2021.100378 |
0.557 |
|
2021 |
Smith CD, Lin CT, McMillin SL, Weyrauch LA, Schmidt CA, Smith CA, Kurland IJ, Witczak CA, Neufer PD. Genetically increasing flux through β-oxidation in skeletal muscle increases mitochondrial reductive stress and glucose intolerance. American Journal of Physiology. Endocrinology and Metabolism. PMID 33813880 DOI: 10.1152/ajpendo.00010.2021 |
0.674 |
|
2021 |
Presby DM, Rudolph MC, Sherk VD, Jackman MR, Foright RM, Jones KL, Houck JA, Johnson GC, Higgins JA, Neufer PD, Eckel RH, MacLean PS. Lipoprotein Lipase Overexpression in Skeletal Muscle Attenuates Weight Regain by Potentiating Energy Expenditure. Diabetes. PMID 33536195 DOI: 10.2337/db20-0763 |
0.312 |
|
2021 |
Murashov AK, Pak ES, Lin CT, Boykov IN, Buddo KA, Mar J, Bhat KM, Neufer PD. Preference and detrimental effects of high fat, sugar, and salt diet in wild-caught Drosophila simulans are reversed by flight exercise. Faseb Bioadvances. 3: 49-64. PMID 33490883 DOI: 10.1096/fba.2020-00079 |
0.571 |
|
2021 |
Schmidt CA, McLaughlin KL, Boykov IN, Mojalagbe R, Ranganathan A, Buddo KA, Lin CT, Fisher-Wellman KH, Neufer PD. Aglycemic growth enhances carbohydrate metabolism and induces sensitivity to menadione in cultured tumor-derived cells. Cancer & Metabolism. 9: 3. PMID 33468237 DOI: 10.1186/s40170-021-00241-0 |
0.661 |
|
2020 |
Fisher-Wellman K, Hagen JT, Neufer PD, Kassai M, Cabot MC. On the nature of ceramide-mitochondria interactions - Dissection using comprehensive mitochondrial phenotyping. Cellular Signalling. 109838. PMID 33212155 DOI: 10.1016/j.cellsig.2020.109838 |
0.636 |
|
2020 |
Ryan TE, Schmidt CA, Tarpey MD, Amorese AJ, Yamaguchi D, Goldberg E, Iñigo MR, Karnekar R, O'Rourke AR, Ervasti JM, Brophy P, Green T, Neufer PD, Fisher-Wellman KH, Spangenburg E, et al. PFKFB3 mediated glycolysis rescues myopathic outcomes in the ischemic limb. Jci Insight. PMID 32841216 DOI: 10.1172/Jci.Insight.139628 |
0.689 |
|
2020 |
Smith CD, Schmidt CA, Lin CT, Fisher-Wellman KH, Neufer PD. Flux through mitochondrial redox circuits linked to nicotinamide nucleotide transhydrogenase generates counterbalance changes in energy expenditure. The Journal of Biological Chemistry. PMID 32747443 DOI: 10.1074/Jbc.Ra120.013899 |
0.731 |
|
2020 |
Pal A, Al-Shaer AE, Guesdon W, Torres MJ, Armstrong M, Quinn K, Davis T, Reisdorph N, Neufer PD, Spangenburg EE, Carroll I, Bazinet RP, Halade GV, Clària J, Shaikh SR. Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32579292 DOI: 10.1096/Fj.202000830R |
0.332 |
|
2020 |
Johnson JM, Verkerke ARP, Maschek JA, Ferrara PJ, Lin CT, Kew KA, Neufer PD, Lodhi IJ, Cox JE, Funai K. Alternative splicing of UCP1 by non-cell-autonomous action of PEMT. Molecular Metabolism. 31: 55-66. PMID 31918922 DOI: 10.1016/J.Molmet.2019.10.007 |
0.586 |
|
2019 |
Verkerke ARP, Ferrara PJ, Lin CT, Johnson JM, Ryan TE, Maschek JA, Eshima H, Paran CW, Laing BT, Siripoksup P, Tippetts TS, Wentzler EJ, Huang H, Spangenburg EE, Brault JJ, ... ... Neufer PD, et al. Phospholipid methylation regulates muscle metabolic rate through Ca transport efficiency. Nature Metabolism. 1: 876-885. PMID 32405618 DOI: 10.1038/s42255-019-0111-2 |
0.62 |
|
2019 |
Iñigo MR, Amorese AJ, Tarpey MD, Balestrieri NP, Jones KG, Patteson DJ, Jackson KC, Torres MJ, Lin CT, Smith CD, Heden TD, McMillin SL, Weyrauch LA, Stanley EC, Schmidt CA, ... ... Neufer PD, et al. Estrogen receptor-α in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation. Molecular Metabolism. 34: 1-15. PMID 32180550 DOI: 10.1016/J.Molmet.2019.12.010 |
0.646 |
|
2019 |
Torres MJ, McLaughlin KL, Renegar RH, Valsaraj S, Whitehurst KS, Sharaf OM, Sharma UM, Horton JL, Sarathy B, Parks JC, Brault JJ, Fisher-Wellman KH, Neufer PD, Virag JAI. Intracardiac administration of ephrinA1-Fc preserves mitochondrial bioenergetics during acute ischemia/reperfusion injury. Life Sciences. 117053. PMID 31733316 DOI: 10.1016/J.Lfs.2019.117053 |
0.599 |
|
2019 |
Heden TD, Johnson JM, Ferrara PJ, Eshima H, Verkerke ARP, Wentzler EJ, Siripoksup P, Narowski TM, Coleman CB, Lin CT, Ryan TE, Reidy PT, de Castro Brás LE, Karner CM, Burant CF, ... ... Neufer PD, et al. Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity. Science Advances. 5: eaax8352. PMID 31535029 DOI: 10.1126/Sciadv.Aax8352 |
0.701 |
|
2019 |
Goldberg EJ, Buddo KA, McLaughlin KL, Fernandez RF, Pereyra AS, Psaltis CE, Lin CT, Hagen JT, Boykov IN, Nguyen TK, Gowdy KM, Ellis JM, Neufer PD, McClung JM, Fisher-Wellman KH. Correction: Tissue-specific characterization of mitochondrial branched-chain keto acid oxidation using a multiplexed assay platform. The Biochemical Journal. 476: 2519. PMID 31519859 DOI: 10.1042/BCJ-2019-0182_COR |
0.71 |
|
2019 |
Neufer PD. Cutting fuel offers new clues in diabetic mystery. Journal of Biological Chemistry. 294: 12328-12329. PMID 31420521 DOI: 10.1074/Jbc.H119.010075 |
0.409 |
|
2019 |
Halling JF, Jessen H, Nøhr-Meldgaard J, Thiellesen Buch B, Masselkhi Christensen N, Gudiksen A, Ringholm S, Neufer PD, Prats C, Pilegaard H. PGC-1α regulates mitochondrial properties beyond biogenesis with aging and exercise training. American Journal of Physiology. Endocrinology and Metabolism. PMID 31265325 DOI: 10.1152/Ajpendo.00059.2019 |
0.458 |
|
2019 |
Goldberg EJ, Buddo KA, McLaughlin KL, Fernandez RF, Pereyra AS, Psaltis CE, Lin CT, Hagen JT, Boykov IN, Nguyen TK, Gowdy KM, Ellis JM, Neufer PD, McClung JM, Fisher-Wellman KH. Tissue-Specific Characterization of Mitochondrial Branched-Chain Keto Acid Oxidation Using a Multiplexed Assay Platform. The Biochemical Journal. PMID 31092703 DOI: 10.1042/Bcj20190182 |
0.761 |
|
2019 |
Kwak HB, Woodlief TL, Green TD, Cox JH, Hickner RC, Neufer PD, Cortright RN. Overexpression of Long-Chain Acyl-CoA Synthetase 5 Increases Fatty Acid Oxidation and Free Radical Formation While Attenuating Insulin Signaling in Primary Human Skeletal Myotubes. International Journal of Environmental Research and Public Health. 16. PMID 30935113 DOI: 10.3390/Ijerph16071157 |
0.512 |
|
2018 |
Ryan TE, Yamaguchi DJ, Schmidt CA, Zeczycki TN, Shaikh SR, Brophy P, Green TD, Tarpey MD, Karnekar R, Goldberg EJ, Sparagna GC, Torres MJ, Annex BH, Neufer PD, Spangenburg EE, et al. Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants. Jci Insight. 3. PMID 30385731 DOI: 10.1172/Jci.Insight.123235 |
0.479 |
|
2018 |
Torres MJ, Ryan TE, Lin CT, Zeczycki TN, Neufer PD. Impact of 17β-estradiol on complex I kinetics and HO production in liver and skeletal muscle mitochondria. The Journal of Biological Chemistry. PMID 30217819 DOI: 10.1074/Jbc.Ra118.005148 |
0.646 |
|
2018 |
Johnson JM, Ferrara PJ, Verkerke ARP, Coleman CB, Wentzler EJ, Neufer PD, Kew KA, de Castro Brás LE, Funai K. Targeted overexpression of catalase to mitochondria does not prevent cardioskeletal myopathy in Barth syndrome. Journal of Molecular and Cellular Cardiology. 121: 94-102. PMID 30008435 DOI: 10.1016/J.Yjmcc.2018.07.001 |
0.425 |
|
2017 |
Heo JW, No MH, Park DH, Kang JH, Seo DY, Han J, Neufer PD, Kwak HB. Effects of exercise on obesity-induced mitochondrial dysfunction in skeletal muscle. The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. 21: 567-577. PMID 29200899 DOI: 10.4196/Kjpp.2017.21.6.567 |
0.527 |
|
2017 |
Sullivan EM, Pennington ER, Sparagna GC, Torres MJ, Neufer PD, Harris M, Washington J, Anderson EJ, Zeczycki TN, Brown DA, Shaikh SR. Docosahexaenoic acid lowers cardiac mitochondrial enzyme activity by replacing linoleic acid in the phospholipidome. The Journal of Biological Chemistry. PMID 29162722 DOI: 10.1074/Jbc.M117.812834 |
0.364 |
|
2017 |
Gavin TP, Ernst JM, Kwak HB, Caudill SE, Reed MA, Garner RT, Nie Y, Weiss JA, Pories WJ, Dar M, Lin CT, Hubal MJ, Neufer PD, Kuang S, Dohm GL. High incomplete skeletal muscle fatty acid oxidation explains low muscle insulin sensitivity in poorly controlled T2D. The Journal of Clinical Endocrinology and Metabolism. PMID 29155999 DOI: 10.1210/Jc.2017-01727 |
0.741 |
|
2017 |
Torres MJ, Kew KA, Ryan TE, Pennington ER, Lin CT, Buddo KA, Fix AM, Smith CA, Gilliam LA, Karvinen S, Lowe DA, Spangenburg EE, Zeczycki TN, Shaikh SR, Neufer PD. 17β-Estradiol Directly Lowers Mitochondrial Membrane Microviscosity and Improves Bioenergetic Function in Skeletal Muscle. Cell Metabolism. PMID 29103922 DOI: 10.1016/J.Cmet.2017.10.003 |
0.64 |
|
2017 |
Heden TD, Ryan TE, Ferrara PJ, Hickner RC, Brophy PM, Neufer PD, McClung JM, Funai K. Greater Oxidative Capacity in Primary Myotubes from Endurance-trained Women. Medicine and Science in Sports and Exercise. PMID 28617704 DOI: 10.1249/Mss.0000000000001352 |
0.417 |
|
2017 |
Kosaraju R, Guesdon W, Crouch MJ, Teague HL, Sullivan EM, Karlsson EA, Schultz-Cherry S, Gowdy K, Bridges LC, Reese LR, Neufer PD, Armstrong M, Reisdorph N, Milner JJ, Beck M, et al. B Cell Activity Is Impaired in Human and Mouse Obesity and Is Responsive to an Essential Fatty Acid upon Murine Influenza Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28500069 DOI: 10.4049/Jimmunol.1601031 |
0.303 |
|
2016 |
Teodoro BG, Sampaio IH, Bomfim LH, Queiroz AL, Silveira LR, Souza AO, Fernandes AM, Eberlin MN, Huang TY, Zheng D, Neufer PD, Cortright RN, Alberici LC. Long-Chain Acyl-CoA Synthetase 6 regulates lipid synthesis and mitochondrial oxidative capacity in human and rat skeletal muscle. The Journal of Physiology. PMID 27647415 DOI: 10.1113/Jp272962 |
0.724 |
|
2016 |
Fisher-Wellman KH, Ryan TE, Smith CD, Gilliam LA, Lin CT, Reese LR, Torres MJ, Neufer PD. A Direct Comparison of Metabolic Responses to High Fat Diet in C57BL/6J and C57BL/6NJ Mice. Diabetes. PMID 27495226 DOI: 10.2337/Db16-0291 |
0.708 |
|
2016 |
Heden TD, Neufer PD, Funai K. Looking Beyond Structure: Membrane Phospholipids of Skeletal Muscle Mitochondria. Trends in Endocrinology and Metabolism: Tem. PMID 27370525 DOI: 10.1016/J.Tem.2016.05.007 |
0.511 |
|
2016 |
Lark DS, Torres MJ, Lin CT, Ryan TE, Anderson EJ, Neufer PD. Direct Real-Time Quantification of Mitochondrial Oxidative Phosphorylation Efficiency in Permeabilized Skeletal Muscle Myofibers. American Journal of Physiology. Cell Physiology. ajpcell.00124.2016. PMID 27335172 DOI: 10.1152/Ajpcell.00124.2016 |
0.615 |
|
2016 |
Gilliam LA, Lark DS, Reese LR, Torres MJ, Ryan TE, Lin CT, Cathey BL, Neufer PD. Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00540.2015. PMID 27329802 DOI: 10.1152/Ajpendo.00540.2015 |
0.675 |
|
2016 |
Ryan TE, Schmidt CA, Green TD, Spangenburg EE, Neufer PD, McClung JM. Targeted expression of Catalase to Mitochondria Protects Against Ischemic Myopathy in High Fat Fed Mice. Diabetes. PMID 27284110 DOI: 10.2337/Db16-0387 |
0.489 |
|
2016 |
Ryan TE, Schmidt CA, Alleman RJ, Tsang AM, Green TD, Neufer PD, Brown DA, McClung JM. Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia. Journal of Molecular and Cellular Cardiology. PMID 27262673 DOI: 10.1016/J.Yjmcc.2016.05.015 |
0.448 |
|
2016 |
Morad SA, Ryan TE, Neufer PD, Zeczycki TN, Davis TS, MacDougall MR, Fox TE, Tan SF, Feith DJ, Loughran TP, Kester M, Claxton DF, Barth BM, Deering TG, Cabot MC. Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia. Journal of Lipid Research. PMID 27140664 DOI: 10.1194/Jlr.M067389 |
0.397 |
|
2016 |
Alleman RJ, Tsang AM, Ryan TE, Patteson DJ, McClung JM, Spangenburg EE, Shaikh SR, Neufer PD, Brown DA. Exercise-induced protection against reperfusion arrhythmia involves stabilization of mitochondrial energetics. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00858.2015. PMID 26945082 DOI: 10.1152/Ajpheart.00858.2015 |
0.406 |
|
2015 |
Ryan TE, Schmidt CA, Green TD, Brown DA, Neufer PD, McClung JM. Mitochondrial Regulation of the Muscle Microenvironment in Critical Limb Ischemia. Frontiers in Physiology. 6: 336. PMID 26635622 DOI: 10.3389/Fphys.2015.00336 |
0.442 |
|
2015 |
Lark DS, Reese LR, Ryan TE, Torres MJ, Smith CD, Lin CT, Neufer PD. Protein Kinase A Governs Oxidative Phosphorylation Kinetics and Oxidant Emitting Potential at Complex I. Frontiers in Physiology. 6: 332. PMID 26635618 DOI: 10.3389/Fphys.2015.00332 |
0.641 |
|
2015 |
Murashov AK, Pak ES, Koury M, Ajmera A, Jeyakumar M, Parker M, Williams O, Ding J, Walters D, Neufer PD. Paternal long-term exercise programs offspring for low energy expenditure and increased risk for obesity in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26506979 DOI: 10.1096/Fj.15-274274 |
0.389 |
|
2015 |
Ferdaoussi M, Dai X, Jensen MV, Wang R, Peterson BS, Huang C, Ilkayeva O, Smith N, Miller N, Hajmrle C, Spigelman AF, Wright RC, Plummer G, Suzuki K, Mackay JP, ... ... Neufer PD, et al. Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells. The Journal of Clinical Investigation. PMID 26389676 DOI: 10.1172/Jci82498 |
0.344 |
|
2015 |
Lark DS, Kang L, Lustig ME, Bonner JS, James FD, Neufer PD, Wasserman DH. Enhanced mitochondrial superoxide scavenging does not improve muscle insulin action in the high fat-fed mouse. Plos One. 10: e0126732. PMID 25992608 DOI: 10.1371/Journal.Pone.0126732 |
0.436 |
|
2015 |
Ludzki A, Paglialunga S, Smith BK, Herbst EA, Allison MK, Heigenhauser GJ, Neufer PD, Holloway GP. Rapid Repression of ADP Transport by Palmitoyl-CoA Is Attenuated by Exercise Training in Humans: A Potential Mechanism to Decrease Oxidative Stress and Improve Skeletal Muscle Insulin Signaling. Diabetes. 64: 2769-79. PMID 25845660 DOI: 10.2337/Db14-1838 |
0.479 |
|
2015 |
Fisher-Wellman KH, Lin CT, Ryan TE, Reese LR, Gilliam LA, Cathey BL, Lark DS, Smith CD, Muoio DM, Neufer PD. Pyruvate dehydrogenase complex and nicotinamide nucleotide transhydrogenase constitute an energy-consuming redox circuit. The Biochemical Journal. 467: 271-80. PMID 25643703 DOI: 10.1042/Bj20141447 |
0.732 |
|
2014 |
Ryan TE, Brophy P, Lin CT, Hickner RC, Neufer PD. Assessment of in vivo skeletal muscle mitochondrial respiratory capacity in humans by near-infrared spectroscopy: a comparison with in situ measurements. The Journal of Physiology. 592: 3231-41. PMID 24951618 DOI: 10.1113/Jphysiol.2014.274456 |
0.67 |
|
2014 |
Kang L, Dai C, Lustig ME, Bonner JS, Mayes WH, Mokshagundam S, James FD, Thompson CS, Lin CT, Perry CG, Anderson EJ, Neufer PD, Wasserman DH, Powers AC. Heterozygous SOD2 deletion impairs glucose-stimulated insulin secretion, but not insulin action, in high-fat-fed mice. Diabetes. 63: 3699-710. PMID 24947366 DOI: 10.2337/Db13-1845 |
0.606 |
|
2014 |
Jackson KC, Gidlund EK, Norrbom J, Valencia AP, Thomson DM, Schuh RA, Neufer PD, Spangenburg EE. BRCA1 is a novel regulator of metabolic function in skeletal muscle. Journal of Lipid Research. 55: 668-80. PMID 24565757 DOI: 10.1194/Jlr.M043851 |
0.468 |
|
2014 |
DeBalsi KL, Wong KE, Koves TR, Slentz DH, Seiler SE, Wittmann AH, Ilkayeva OR, Stevens RD, Perry CG, Lark DS, Hui ST, Szweda L, Neufer PD, Muoio DM. Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle. The Journal of Biological Chemistry. 289: 8106-20. PMID 24482226 DOI: 10.1074/Jbc.M113.511535 |
0.506 |
|
2014 |
Brown DA, Hale SL, Baines CP, del Rio CL, Hamlin RL, Yueyama Y, Kijtawornrat A, Yeh ST, Frasier CR, Stewart LM, Moukdar F, Shaikh SR, Fisher-Wellman KH, Neufer PD, Kloner RA. Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia. Journal of Cardiovascular Pharmacology and Therapeutics. 19: 121-32. PMID 24288396 DOI: 10.1177/1074248413508003 |
0.619 |
|
2014 |
Rogers C, Davis B, Neufer PD, Murphy MP, Anderson EJ, Robidoux J. A transient increase in lipid peroxidation primes preadipocytes for delayed mitochondrial inner membrane permeabilization and ATP depletion during prolonged exposure to fatty acids. Free Radical Biology & Medicine. 67: 330-41. PMID 24269897 DOI: 10.1016/J.Freeradbiomed.2013.11.012 |
0.425 |
|
2014 |
Fisher-Wellman KH, Weber TM, Cathey BL, Brophy PM, Gilliam LA, Kane CL, Maples JM, Gavin TP, Houmard JA, Neufer PD. Mitochondrial respiratory capacity and content are normal in young insulin-resistant obese humans. Diabetes. 63: 132-41. PMID 23974920 DOI: 10.2337/Db13-0940 |
0.681 |
|
2013 |
Smith BK, Perry CG, Herbst EA, Ritchie IR, Beaudoin MS, Smith JC, Neufer PD, Wright DC, Holloway GP. Submaximal ADP-stimulated respiration is impaired in ZDF rats and recovered by resveratrol. The Journal of Physiology. 591: 6089-101. PMID 24081154 DOI: 10.1113/Jphysiol.2013.259226 |
0.52 |
|
2013 |
Fisher-Wellman KH, Gilliam LA, Lin CT, Cathey BL, Lark DS, Neufer PD. Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload. Free Radical Biology & Medicine. 65: 1201-8. PMID 24056031 DOI: 10.1016/J.Freeradbiomed.2013.09.008 |
0.76 |
|
2013 |
Gilliam LA, Fisher-Wellman KH, Lin CT, Maples JM, Cathey BL, Neufer PD. The anticancer agent doxorubicin disrupts mitochondrial energy metabolism and redox balance in skeletal muscle. Free Radical Biology & Medicine. 65: 988-96. PMID 24017970 DOI: 10.1016/J.Freeradbiomed.2013.08.191 |
0.777 |
|
2013 |
Fisher-Wellman KH, Mattox TA, Thayne K, Katunga LA, La Favor JD, Neufer PD, Hickner RC, Wingard CJ, Anderson EJ. Novel role for thioredoxin reductase-2 in mitochondrial redox adaptations to obesogenic diet and exercise in heart and skeletal muscle. The Journal of Physiology. 591: 3471-86. PMID 23613536 DOI: 10.1113/Jphysiol.2013.254193 |
0.682 |
|
2013 |
Perry CG, Kane DA, Lanza IR, Neufer PD. Methods for assessing mitochondrial function in diabetes. Diabetes. 62: 1041-53. PMID 23520284 DOI: 10.2337/Db12-1219 |
0.435 |
|
2013 |
Brown DA, Patel HD, Moukdar F, Shaikh SR, Harris M, Fisher-Wellman K, Neufer PD, Hale SL, Dai W, Kloner RA. Preserving mitochondrial function during acute coronary syndromes with the mitochondria-targeting peptide Bendavia Mitochondrion. 13: 923. DOI: 10.1016/J.Mito.2013.07.065 |
0.619 |
|
2012 |
Lark DS, Fisher-Wellman KH, Neufer PD. High-fat load: mechanism(s) of insulin resistance in skeletal muscle. International Journal of Obesity Supplements. 2: S31-S36. PMID 26052434 DOI: 10.1038/ijosup.2012.20 |
0.708 |
|
2012 |
Smith BK, Perry CG, Koves TR, Wright DC, Smith JC, Neufer PD, Muoio DM, Holloway GP. Identification of a novel malonyl-CoA IC(50) for CPT-I: implications for predicting in vivo fatty acid oxidation rates. The Biochemical Journal. 448: 13-20. PMID 22928974 DOI: 10.1042/Bj20121110 |
0.336 |
|
2012 |
Perry CG, Kane DA, Herbst EA, Mukai K, Lark DS, Wright DC, Heigenhauser GJ, Neufer PD, Spriet LL, Holloway GP. Mitochondrial creatine kinase activity and phosphate shuttling are acutely regulated by exercise in human skeletal muscle. The Journal of Physiology. 590: 5475-86. PMID 22907058 DOI: 10.1113/Jphysiol.2012.234682 |
0.433 |
|
2012 |
Gilliam LA, Neufer PD. Transgenic mouse models resistant to diet-induced metabolic disease: is energy balance the key? The Journal of Pharmacology and Experimental Therapeutics. 342: 631-6. PMID 22700428 DOI: 10.1124/Jpet.112.192146 |
0.351 |
|
2012 |
Kang L, Lustig ME, Bonner JS, Lee-Young RS, Mayes WH, James FD, Lin CT, Perry CG, Anderson EJ, Neufer PD, Wasserman DH. Mitochondrial antioxidative capacity regulates muscle glucose uptake in the conscious mouse: effect of exercise and diet. Journal of Applied Physiology (Bethesda, Md. : 1985). 113: 1173-83. PMID 22653994 DOI: 10.1152/Japplphysiol.01344.2011 |
0.618 |
|
2012 |
Muoio DM, Neufer PD. Lipid-induced mitochondrial stress and insulin action in muscle. Cell Metabolism. 15: 595-605. PMID 22560212 DOI: 10.1016/J.Cmet.2012.04.010 |
0.529 |
|
2012 |
Fisher-Wellman KH, Neufer PD. Linking mitochondrial bioenergetics to insulin resistance via redox biology. Trends in Endocrinology and Metabolism: Tem. 23: 142-53. PMID 22305519 DOI: 10.1016/J.Tem.2011.12.008 |
0.645 |
|
2012 |
Kwak HB, Thalacker-Mercer A, Anderson EJ, Lin CT, Kane DA, Lee NS, Cortright RN, Bamman MM, Neufer PD. Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes. Free Radical Biology & Medicine. 52: 198-207. PMID 22080086 DOI: 10.1016/J.Freeradbiomed.2011.10.449 |
0.687 |
|
2012 |
Boyle KE, Zheng D, Anderson EJ, Neufer PD, Houmard JA. Mitochondrial lipid oxidation is impaired in cultured myotubes from obese humans. International Journal of Obesity (2005). 36: 1025-31. PMID 22024640 DOI: 10.1038/Ijo.2011.201 |
0.688 |
|
2011 |
Perry CG, Kane DA, Lin CT, Kozy R, Cathey BL, Lark DS, Kane CL, Brophy PM, Gavin TP, Anderson EJ, Neufer PD. Inhibiting myosin-ATPase reveals a dynamic range of mitochondrial respiratory control in skeletal muscle. The Biochemical Journal. 437: 215-22. PMID 21554250 DOI: 10.1042/Bj20110366 |
0.647 |
|
2011 |
Kang L, Ayala JE, Lee-Young RS, Zhang Z, James FD, Neufer PD, Pozzi A, Zutter MM, Wasserman DH. Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice. Diabetes. 60: 416-26. PMID 21270253 DOI: 10.2337/Db10-1116 |
0.377 |
|
2011 |
Boyle KE, Canham JP, Consitt LA, Zheng D, Koves TR, Gavin TP, Holbert D, Neufer PD, Ilkayeva O, Muoio DM, Houmard JA. A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals. The Journal of Clinical Endocrinology and Metabolism. 96: 775-81. PMID 21190973 DOI: 10.1210/Jc.2010-2253 |
0.659 |
|
2011 |
Kane DA, Lin CT, Anderson EJ, Kwak HB, Cox JH, Brophy PM, Hickner RC, Neufer PD, Cortright RN. Progesterone increases skeletal muscle mitochondrial H2O2 emission in nonmenopausal women. American Journal of Physiology. Endocrinology and Metabolism. 300: E528-35. PMID 21189359 DOI: 10.1152/Ajpendo.00389.2010 |
0.618 |
|
2011 |
Williams RS, Neufer PD. Regulation of Gene Expression in Skeletal Muscle by Contractile Activity Comprehensive Physiology. 1124-1150. DOI: 10.1002/Cphy.Cp120125 |
0.436 |
|
2010 |
Bikman BT, Zheng D, Kane DA, Anderson EJ, Woodlief TL, Price JW, Dohm GL, Neufer PD, Cortright RN. Metformin Improves Insulin Signaling in Obese Rats via Reduced IKKbeta Action in a Fiber-Type Specific Manner. Journal of Obesity. 2010. PMID 20798864 DOI: 10.1155/2010/970865 |
0.788 |
|
2010 |
Kane DA, Anderson EJ, Price JW, Woodlief TL, Lin CT, Bikman BT, Cortright RN, Neufer PD. Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats. Free Radical Biology & Medicine. 49: 1082-7. PMID 20600832 DOI: 10.1016/J.Freeradbiomed.2010.06.022 |
0.764 |
|
2010 |
Lin C, Kane DA, Lark DS, Fisher-Wellman KH, Zheng D, Perry CG, Kane CL, Kozy R, Tapscott EB, Ellis RJ, Woodlief TL, Neufer PD. β-GPA Prevents High-fat Induced Mitochondrial H2O2 Emission And Insulin Resistance Independent of AMPK In Mice Medicine & Science in Sports & Exercise. 42: 22. DOI: 10.1249/01.Mss.0000389527.98518.Fd |
0.787 |
|
2010 |
Perry CG, Kane DA, Kozy R, Kane CL, Lark DS, Lin C, Brophy P, Gavin TP, Anderson EJ, Neufer PD. Contraction Increases Mitochondrial Respiratory Sensitivity to ADP at Body Temperature in Human Permeabilized Myofibers Medicine & Science in Sports & Exercise. 42: 98. DOI: 10.1249/01.Mss.0000389461.47901.94 |
0.624 |
|
2010 |
Kwak H, Lin C, Kane DA, Lee N, Boyle KE, Houmard JA, Cortright RN, Neufer PD. Simvastatin Increases Mitochondrial Oxidative Stress and Reduces Mitochondrial Ca2+ Retention Capacity in Human Skeletal Myotubes Medicine & Science in Sports & Exercise. 42: 59. DOI: 10.1249/01.Mss.0000389360.98999.Bc |
0.64 |
|
2009 |
Anderson EJ, Kypson AP, Rodriguez E, Anderson CA, Lehr EJ, Neufer PD. Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart. Journal of the American College of Cardiology. 54: 1891-8. PMID 19892241 DOI: 10.1016/J.Jacc.2009.07.031 |
0.392 |
|
2009 |
Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin CT, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD. Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. The Journal of Clinical Investigation. 119: 573-81. PMID 19188683 DOI: 10.1172/Jci37048 |
0.702 |
|
2007 |
Anderson EJ, Yamazaki H, Neufer PD. Induction of endogenous uncoupling protein 3 suppresses mitochondrial oxidant emission during fatty acid-supported respiration. The Journal of Biological Chemistry. 282: 31257-66. PMID 17761668 DOI: 10.1074/Jbc.M706129200 |
0.485 |
|
2006 |
Wu JJ, Roth RJ, Anderson EJ, Hong EG, Lee MK, Choi CS, Neufer PD, Shulman GI, Kim JK, Bennett AM. Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity. Cell Metabolism. 4: 61-73. PMID 16814733 DOI: 10.1016/J.Cmet.2006.05.010 |
0.346 |
|
2006 |
Anderson EJ, Neufer PD. Type II skeletal myofibers possess unique properties that potentiate mitochondrial H(2)O(2) generation. American Journal of Physiology. Cell Physiology. 290: C844-51. PMID 16251473 DOI: 10.1152/Ajpcell.00402.2005 |
0.481 |
|
2006 |
DiPietro L, Dziura J, Yeckel CW, Neufer PD. Exercise and improved insulin sensitivity in older women: evidence of the enduring benefits of higher intensity training. Journal of Applied Physiology (Bethesda, Md. : 1985). 100: 142-9. PMID 16141382 DOI: 10.1097/01823246-200617020-00011 |
0.307 |
|
2005 |
Lundby C, Nordsborg N, Kusuhara K, Kristensen KM, Neufer PD, Pilegaard H. Gene expression in human skeletal muscle: alternative normalization method and effect of repeated biopsies. European Journal of Applied Physiology. 95: 351-60. PMID 16151837 DOI: 10.1007/S00421-005-0022-7 |
0.347 |
|
2005 |
Pilegaard H, Osada T, Andersen LT, Helge JW, Saltin B, Neufer PD. Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise. Metabolism: Clinical and Experimental. 54: 1048-55. PMID 16092055 DOI: 10.1016/J.Metabol.2005.03.008 |
0.401 |
|
2005 |
Jørgensen SB, Wojtaszewski JF, Viollet B, Andreelli F, Birk JB, Hellsten Y, Schjerling P, Vaulont S, Neufer PD, Richter EA, Pilegaard H. Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1146-8. PMID 15878932 DOI: 10.1096/Fj.04-3144Fje |
0.316 |
|
2004 |
Jensen L, Pilegaard H, Neufer PD, Hellsten Y. Effect of acute exercise and exercise training on VEGF splice variants in human skeletal muscle. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 287: R397-402. PMID 15117722 DOI: 10.1152/Ajpregu.00071.2004 |
0.311 |
|
2003 |
Hildebrandt AL, Pilegaard H, Neufer PD. Differential transcriptional activation of select metabolic genes in response to variations in exercise intensity and duration. American Journal of Physiology. Endocrinology and Metabolism. 285: E1021-7. PMID 12902322 DOI: 10.1152/Ajpendo.00234.2003 |
0.337 |
|
2003 |
Pilegaard H, Saltin B, Neufer PD. Effect of short-term fasting and refeeding on transcriptional regulation of metabolic genes in human skeletal muscle. Diabetes. 52: 657-62. PMID 12606505 DOI: 10.2337/Diabetes.52.3.657 |
0.415 |
|
2003 |
Pilegaard H, Saltin B, Neufer PD. Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle. The Journal of Physiology. 546: 851-8. PMID 12563009 DOI: 10.1113/Jphysiol.2002.034850 |
0.382 |
|
2002 |
Stoppani J, Hildebrandt AL, Sakamoto K, Cameron-Smith D, Goodyear LJ, Neufer PD. AMP-activated protein kinase activates transcription of the UCP3 and HKII genes in rat skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism. 283: E1239-48. PMID 12388122 DOI: 10.1152/Ajpendo.00278.2002 |
0.418 |
|
2002 |
Pilegaard H, Keller C, Steensberg A, Helge JW, Pedersen BK, Saltin B, Neufer PD. Influence of pre-exercise muscle glycogen content on exercise-induced transcriptional regulation of metabolic genes. The Journal of Physiology. 541: 261-71. PMID 12015434 DOI: 10.1113/Jphysiol.2002.016832 |
0.37 |
|
2001 |
Keller C, Steensberg A, Pilegaard H, Osada T, Saltin B, Pedersen BK, Neufer PD. Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2748-50. PMID 11687509 DOI: 10.1096/Fj.01-0507Fje |
0.352 |
|
2000 |
Pilegaard H, Ordway GA, Saltin B, Neufer PD. Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise. American Journal of Physiology. Endocrinology and Metabolism. 279: E806-14. PMID 11001762 DOI: 10.1152/Ajpendo.2000.279.4.E806 |
0.349 |
|
2000 |
Hildebrandt AL, Neufer PD. Exercise attenuates the fasting-induced transcriptional activation of metabolic genes in skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism. 278: E1078-86. PMID 10827011 |
0.338 |
|
2000 |
Ordway GA, Neufer PD, Chin ER, DeMartino GN. Chronic contractile activity upregulates the proteasome system in rabbit skeletal muscle. Journal of Applied Physiology (Bethesda, Md. : 1985). 88: 1134-41. PMID 10710413 DOI: 10.1152/Jappl.2000.88.3.1134 |
0.41 |
|
1998 |
Neufer PD, Ordway GA, Williams RS. Transient regulation of c-fos, alpha B-crystallin, and hsp70 in muscle during recovery from contractile activity. The American Journal of Physiology. 274: C341-6. PMID 9486122 DOI: 10.1152/Ajpcell.1998.274.2.C341 |
0.433 |
|
1996 |
Neufer PD, Ordway GA, Hand GA, Shelton JM, Richardson JA, Benjamin IJ, Williams RS. Continuous contractile activity induces fiber type specific expression of HSP70 in skeletal muscle. The American Journal of Physiology. 271: C1828-37. PMID 8997182 DOI: 10.1152/AJPCELL.1996.271.6.C1828 |
0.332 |
|
1996 |
Garry DJ, Bassel-Duby RS, Richardson JA, Grayson J, Neufer PD, Williams RS. Postnatal development and plasticity of specialized muscle fiber characteristics in the hindlimb. Developmental Genetics. 19: 146-56. PMID 8900047 DOI: 10.1002/(Sici)1520-6408(1996)19:2<146::Aid-Dvg6>3.0.Co;2-9 |
0.452 |
|
1995 |
Neufer PD, Devente JE, Tapscott EB, Dohm GL. Hindlimb perfusion induces GLUT-1 and immediate early gene expression in skeletal muscle. The American Journal of Physiology. 268: E866-72. PMID 7762639 |
0.536 |
|
1995 |
Li K, Neufer PD, Williams RS. Nuclear responses to depletion of mitochondrial DNA in human cells. The American Journal of Physiology. 269: C1265-70. PMID 7491917 |
0.413 |
|
1994 |
Carey JO, Neufer PD, Farrar RP, Veerkamp JH, Dohm GL. Transcriptional regulation of muscle fatty acid-binding protein. The Biochemical Journal. 298: 613-7. PMID 8141774 |
0.542 |
|
1993 |
Megeney LA, Neufer PD, Dohm GL, Tan MH, Blewett CA, Elder GC, Bonen A. Effects of muscle activity and fiber composition on glucose transport and GLUT-4. The American Journal of Physiology. 264: E583-93. PMID 8476037 |
0.556 |
|
1993 |
Houmard JA, Hortobágyi T, Neufer PD, Johns RA, Fraser DD, Israel RG, Dohm GL. Training cessation does not alter GLUT-4 protein levels in human skeletal muscle. Journal of Applied Physiology (Bethesda, Md. : 1985). 74: 776-81. PMID 8458795 DOI: 10.1152/Jappl.1993.74.2.776 |
0.517 |
|
1993 |
Neufer PD, Carey JO, Dohm GL. Transcriptional regulation of the gene for glucose transporter GLUT4 in skeletal muscle. Effects of diabetes and fasting. The Journal of Biological Chemistry. 268: 13824-9. PMID 7686145 |
0.562 |
|
1993 |
Neufer PD, Dohm GL. Exercise induces a transient increase in transcription of the GLUT-4 gene in skeletal muscle. The American Journal of Physiology. 265: C1597-603. PMID 7506491 |
0.529 |
|
1992 |
Neufer PD, Shinebarger MH, Dohm GL. Effect of training and detraining on skeletal muscle glucose transporter (GLUT4) content in rats. Canadian Journal of Physiology and Pharmacology. 70: 1286-90. PMID 1493596 |
0.532 |
|
1991 |
Houmard JA, Egan PC, Neufer PD, Friedman JE, Wheeler WS, Israel RG, Dohm GL. Elevated skeletal muscle glucose transporter levels in exercise-trained middle-aged men. The American Journal of Physiology. 261: E437-43. PMID 1928336 DOI: 10.1152/Ajpendo.1991.261.4.E437 |
0.521 |
|
1991 |
Friedman JE, Neufer PD, Dohm GL. Regulation of glycogen resynthesis following exercise. Dietary considerations. Sports Medicine (Auckland, N.Z.). 11: 232-43. PMID 1901662 DOI: 10.2165/00007256-199111040-00003 |
0.591 |
|
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