| Year |
Citation |
Score |
| 2023 |
Netterfield TS, Ostheimer GJ, Tentner AR, Joughin BA, Dakoyannis AM, Sharma CD, Sorger PK, Janes KA, Lauffenburger DA, Yaffe MB. Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition. Cell Systems. 14: 582-604.e10. PMID 37473730 DOI: 10.1016/j.cels.2023.06.005 |
0.332 |
|
| 2021 |
Lopacinski AB, Sweatt AJ, Smolko CM, Gray-Gaillard E, Borgman CA, Shah M, Janes KA. Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback. Cell Systems. PMID 33740397 DOI: 10.1016/j.cels.2021.02.004 |
0.583 |
|
| 2021 |
Singh S, Sutcliffe MD, Repich K, Atkins KA, Harvey JA, Janes KA. Pan-cancer Drivers are Recurrent Transcriptional Regulatory Heterogeneities in Early-stage Luminal Breast Cancer. Cancer Research. PMID 33531373 DOI: 10.1158/0008-5472.CAN-20-1034 |
0.311 |
|
| 2018 |
Borten MA, Bajikar SS, Sasaki N, Clevers H, Janes KA. Automated brightfield morphometry of 3D organoid populations by OrganoSeg. Scientific Reports. 8: 5319. PMID 29593296 DOI: 10.1038/S41598-017-18815-8 |
0.732 |
|
| 2017 |
Bajikar SS, Wang CC, Borten MA, Pereira EJ, Atkins KA, Janes KA. Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer. Developmental Cell. 43: 418-435.e13. PMID 29161592 DOI: 10.1016/J.Devcel.2017.10.027 |
0.736 |
|
| 2017 |
Janes KA, Chandran PL, Ford RM, Lazzara MJ, Papin JA, Peirce SM, Saucerman JJ, Lauffenburger DA. An engineering design approach to systems biology. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 28590470 DOI: 10.1039/C7Ib00014F |
0.555 |
|
| 2017 |
Shah M, Smolko CM, Kinicki S, Chapman ZD, Brautigan DL, Janes KA. Profiling Subcellular Protein Phosphatase Responses to Coxsackievirus B3 Infection of Cardiomyocytes. Molecular & Cellular Proteomics : McP. PMID 28174228 DOI: 10.1074/Mcp.O116.063487 |
0.63 |
|
| 2017 |
Pereira E, Janes K. Abstract 3954: Single-cell misregulation of NRF2 in basal-like breast cancer Cancer Research. 77: 3954-3954. DOI: 10.1158/1538-7445.Am2017-3954 |
0.461 |
|
| 2016 |
Chitforoushzadeh Z, Ye Z, Sheng Z, LaRue S, Fry RC, Lauffenburger DA, Janes KA. TNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data tensors. Science Signaling. 9: ra59. PMID 27273097 DOI: 10.1126/Scisignal.Aad3373 |
0.619 |
|
| 2016 |
Janes KA, VanHook AM. Science Signaling Podcast for 7 June 2016: Modeling signal integration. Science Signaling. 9: pc13. PMID 27273095 DOI: 10.1126/Scisignal.Aag1902 |
0.397 |
|
| 2016 |
Jensen KJ, Moyer CB, Janes KA. Network Architecture Predisposes an Enzyme to Either Pharmacologic or Genetic Targeting. Cell Systems. 2: 112-121. PMID 26942229 DOI: 10.1016/j.cels.2016.01.012 |
0.579 |
|
| 2014 |
Wang CC, Janes KA. Non-genetic heterogeneity caused by differential single-cell adhesion. Cell Cycle (Georgetown, Tex.). 13: 2149-50. PMID 24956151 DOI: 10.4161/Cc.29660 |
0.353 |
|
| 2014 |
Wang CC, Bajikar SS, Jamal L, Atkins KA, Janes KA. A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies. Nature Cell Biology. 16: 345-56. PMID 24658685 DOI: 10.1038/Ncb2930 |
0.748 |
|
| 2014 |
Bajikar SS, Fuchs C, Roller A, Theis FJ, Janes KA. Parameterizing cell-to-cell regulatory heterogeneities via stochastic transcriptional profiles. Proceedings of the National Academy of Sciences of the United States of America. 111: E626-35. PMID 24449900 DOI: 10.1073/pnas.1311647111 |
0.758 |
|
| 2013 |
Kang BH, Jensen KJ, Hatch JA, Janes KA. Simultaneous profiling of 194 distinct receptor transcripts in human cells. Science Signaling. 6: rs13. PMID 23921087 DOI: 10.1126/scisignal.2003624 |
0.619 |
|
| 2013 |
Janes KA, Lauffenburger DA. Models of signalling networks - what cell biologists can gain from them and give to them. Journal of Cell Science. 126: 1913-21. PMID 23720376 DOI: 10.1242/jcs.112045 |
0.503 |
|
| 2013 |
Jensen KJ, Garmaroudi FS, Zhang J, Lin J, Boroomand S, Zhang M, Luo Z, Yang D, Luo H, McManus BM, Janes KA. An ERK-p38 subnetwork coordinates host cell apoptosis and necrosis during coxsackievirus B3 infection. Cell Host & Microbe. 13: 67-76. PMID 23332156 DOI: 10.1016/J.Chom.2012.11.009 |
0.625 |
|
| 2013 |
Wang L, Janes KA. Stochastic profiling of transcriptional regulatory heterogeneities in tissues, tumors and cultured cells. Nature Protocols. 8: 282-301. PMID 23306461 DOI: 10.1038/Nprot.2012.158 |
0.313 |
|
| 2012 |
Jensen KJ, Janes KA. Modeling the latent dimensions of multivariate signaling datasets. Physical Biology. 9: 045004. PMID 22871687 DOI: 10.1088/1478-3975/9/4/045004 |
0.664 |
|
| 2012 |
Bajikar SS, Janes KA. Multiscale models of cell signaling. Annals of Biomedical Engineering. 40: 2319-27. PMID 22476894 DOI: 10.1007/s10439-012-0560-1 |
0.773 |
|
| 2012 |
Wang L, Janes K. Abstract 1082: Stochastic control of abnormal morphogenesis induced by the ErbB2 oncoprotein Cancer Research. 72: 1082-1082. DOI: 10.1158/1538-7445.Am2012-1082 |
0.42 |
|
| 2011 |
Wang L, Brugge JS, Janes KA. Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 108: E803-12. PMID 21873240 DOI: 10.1073/Pnas.1103423108 |
0.374 |
|
| 2011 |
Janes K, Wang C, Jamal L, Bajikar S, Atkins K. Abstract SY17-01: Heterogeneous single-cell expression programs and basal-like breast cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy17-01 |
0.782 |
|
| 2010 |
Janes KA, Wang CC, Holmberg KJ, Cabral K, Brugge JS. Identifying single-cell molecular programs by stochastic profiling. Nature Methods. 7: 311-7. PMID 20228812 DOI: 10.1038/Nmeth.1442 |
0.366 |
|
| 2008 |
Janes KA, Reinhardt HC, Yaffe MB. Cytokine-induced signaling networks prioritize dynamic range over signal strength. Cell. 135: 343-54. PMID 18957207 DOI: 10.1016/J.Cell.2008.08.034 |
0.35 |
|
| 2007 |
Miller-Jensen K, Janes KA, Brugge JS, Lauffenburger DA. Common effector processing mediates cell-specific responses to stimuli. Nature. 448: 604-8. PMID 17637676 DOI: 10.1038/Nature06001 |
0.571 |
|
| 2006 |
Miller-Jensen K, Janes KA, Wong YL, Griffith LG, Lauffenburger DA. Adenoviral vector saturates Akt pro-survival signaling and blocks insulin-mediated rescue of tumor necrosis-factor-induced apoptosis. Journal of Cell Science. 119: 3788-98. PMID 16940353 DOI: 10.1242/Jcs.03102 |
0.55 |
|
| 2006 |
Kumar N, Hendriks BS, Janes KA, de Graaf D, Lauffenburger DA. Applying computational modeling to drug discovery and development. Drug Discovery Today. 11: 806-11. PMID 16935748 DOI: 10.1016/j.drudis.2006.07.010 |
0.426 |
|
| 2006 |
Janes KA, Gaudet S, Albeck JG, Nielsen UB, Lauffenburger DA, Sorger PK. The response of human epithelial cells to TNF involves an inducible autocrine cascade. Cell. 124: 1225-39. PMID 16564013 DOI: 10.1016/j.cell.2006.01.041 |
0.469 |
|
| 2006 |
Janes KA, Lauffenburger DA. A biological approach to computational models of proteomic networks. Current Opinion in Chemical Biology. 10: 73-80. PMID 16406679 DOI: 10.1016/j.cbpa.2005.12.016 |
0.435 |
|
| 2005 |
Janes KA, Albeck JG, Gaudet S, Sorger PK, Lauffenburger DA, Yaffe MB. A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis. Science (New York, N.Y.). 310: 1646-53. PMID 16339439 DOI: 10.1126/Science.1116598 |
0.562 |
|
| 2005 |
Gaudet S, Janes KA, Albeck JG, Pace EA, Lauffenburger DA, Sorger PK. A compendium of signals and responses triggered by prodeath and prosurvival cytokines. Molecular & Cellular Proteomics : McP. 4: 1569-90. PMID 16030008 DOI: 10.1074/mcp.M500158-MCP200 |
0.592 |
|
| 2005 |
Shults MD, Janes KA, Lauffenburger DA, Imperiali B. A multiplexed homogeneous fluorescence-based assay for protein kinase activity in cell lysates. Nature Methods. 2: 277-83. PMID 15782220 DOI: 10.1038/Nmeth747 |
0.414 |
|
| 2004 |
Janes KA, Kelly JR, Gaudet S, Albeck JG, Sorger PK, Lauffenburger DA. Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 11: 544-61. PMID 15579231 DOI: 10.1089/1066527041887258 |
0.582 |
|
| 2004 |
Janes KA, Albeck JG, Gaudet S, Nielsen UB, Sorger PK, Lauffenburger DA, Yaffe MB. MULTIVARIATE APPROACHES FOR REVEALING BIOLOGICAL SIGNAL-RESPONSE RELATIONSHIPS RELEVANT TO SEPSIS Shock. 21: 3. DOI: 10.1097/00024382-200403001-00009 |
0.453 |
|
| 2003 |
Janes KA, Albeck JG, Peng LX, Sorger PK, Lauffenburger DA, Yaffe MB. A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis. Molecular & Cellular Proteomics : McP. 2: 463-73. PMID 12832460 DOI: 10.1074/Mcp.M300045-Mcp200 |
0.539 |
|
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