Nicholas E. Hoffman, Ph.D. - Publications

Affiliations: 
2014 Biochemistry Temple University, Philadelphia, PA, United States 
Area:
Biochemistry

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Joseph LC, Kokkinaki D, Valenti MC, Kim GJ, Barca E, Tomar D, Hoffman NE, Subramanyam P, Colecraft HM, Hirano M, Ratner AJ, Madesh M, Drosatos K, Morrow JP. Inhibition of NADPH oxidase 2 (NOX2) prevents sepsis-induced cardiomyopathy by improving calcium handling and mitochondrial function. Jci Insight. 2. PMID 28878116 DOI: 10.1172/Jci.Insight.94248  0.334
2016 Tomar D, Dong Z, Shanmughapriya S, Koch DA, Thomas T, Hoffman NE, Timbalia SA, Goldman SJ, Breves SL, Corbally DP, Nemani N, Fairweather JP, Cutri AR, Zhang X, Song J, et al. MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics. Cell Reports. PMID 27184846 DOI: 10.1016/J.Celrep.2016.04.050  0.508
2016 Zhou J, Ahmad F, Parikh S, Hoffman NE, Rajan S, Verma VK, Song J, Yuan A, Shanmughapriya S, Guo Y, Gao E, Koch WJ, Woodgett JR, Muniswamy M, Kishore R, et al. Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy. Circulation Research. PMID 26976650 DOI: 10.1161/Circresaha.116.308544  0.581
2016 Feldman AM, Gordon J, Wang J, Song J, Zhang XQ, Myers VD, Tilley DG, Gao E, Hoffman NE, Tomar D, Madesh M, Rabinowitz J, Koch WJ, Su F, Khalili K, et al. BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes. Journal of Molecular and Cellular Cardiology. PMID 26796036 DOI: 10.1016/J.Yjmcc.2016.01.015  0.457
2015 Shanmughapriya S, Rajan S, Hoffman NE, Higgins AM, Tomar D, Nemani N, Hines KJ, Smith DJ, Eguchi A, Vallem S, Shaikh F, Cheung M, Leonard NJ, Stolakis RS, Wolfers MP, et al. SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore. Molecular Cell. 60: 47-62. PMID 26387735 DOI: 10.1016/J.Molcel.2015.08.009  0.521
2015 Shanmughapriya S, Rajan S, Hoffman NE, Zhang X, Guo S, Kolesar JE, Hines KJ, Ragheb J, Jog NR, Caricchio R, Baba Y, Zhou Y, Kaufman BA, Cheung JY, Kurosaki T, et al. Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU. Science Signaling. 8: ra23. PMID 25737585 DOI: 10.1126/scisignal.2005673  0.572
2015 Hoffman NE, Miller BA, Wang J, Elrod JW, Rajan S, Gao E, Song J, Zhang XQ, Hirschler-Laszkiewicz I, Shanmughapriya S, Koch WJ, Feldman AM, Madesh M, Cheung JY. Ca²⁺ entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance. American Journal of Physiology. Heart and Circulatory Physiology. 308: H637-50. PMID 25576627 DOI: 10.1152/Ajpheart.00720.2014  0.508
2014 Doonan PJ, Chandramoorthy HC, Hoffman NE, Zhang X, Cárdenas C, Shanmughapriya S, Rajan S, Vallem S, Chen X, Foskett JK, Cheung JY, Houser SR, Madesh M. LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4936-49. PMID 25077561 DOI: 10.1096/Fj.14-256453  0.678
2014 Makarewich CA, Zhang H, Davis J, Correll RN, Trappanese DM, Hoffman NE, Troupes CD, Berretta RM, Kubo H, Madesh M, Chen X, Gao E, Molkentin JD, Houser SR. Transient receptor potential channels contribute to pathological structural and functional remodeling after myocardial infarction. Circulation Research. 115: 567-80. PMID 25047165 DOI: 10.1161/Circresaha.115.303831  0.362
2014 Brailoiu GC, Deliu E, Marcu J, Hoffman NE, Console-Bram L, Zhao P, Madesh M, Abood ME, Brailoiu E. Differential activation of intracellular versus plasmalemmal CB2 cannabinoid receptors. Biochemistry. 53: 4990-9. PMID 25033246 DOI: 10.1021/Bi500632A  0.315
2014 Miller BA, Hoffman NE, Merali S, Zhang XQ, Wang J, Rajan S, Shanmughapriya S, Gao E, Barrero CA, Mallilankaraman K, Song J, Gu T, Hirschler-Laszkiewicz I, Koch WJ, Feldman AM, et al. TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria. The Journal of Biological Chemistry. 289: 7615-29. PMID 24492610 DOI: 10.1074/Jbc.M113.533851  0.363
2014 Hoffman NE, Chandramoorthy HC, Shanmughapriya S, Zhang XQ, Vallem S, Doonan PJ, Malliankaraman K, Guo S, Rajan S, Elrod JW, Koch WJ, Cheung JY, Madesh M. SLC25A23 augments mitochondrial Ca²⁺ uptake, interacts with MCU, and induces oxidative stress-mediated cell death. Molecular Biology of the Cell. 25: 936-47. PMID 24430870 DOI: 10.1091/Mbc.E13-08-0502  0.676
2013 Hoffman NE, Chandramoorthy HC, Shamugapriya S, Zhang X, Rajan S, Mallilankaraman K, Gandhirajan RK, Vagnozzi RJ, Ferrer LM, Sreekrishnanilayam K, Natarajaseenivasan K, Vallem S, Force T, Choi ET, Cheung JY, et al. MICU1 motifs define mitochondrial calcium uniporter binding and activity. Cell Reports. 5: 1576-88. PMID 24332854 DOI: 10.1016/J.Celrep.2013.11.026  0.495
2013 Yu J, Deliu E, Zhang XQ, Hoffman NE, Carter RL, Grisanti LA, Brailoiu GC, Madesh M, Cheung JY, Force T, Abood ME, Koch WJ, Tilley DG, Brailoiu E. Differential activation of cultured neonatal cardiomyocytes by plasmalemmal versus intracellular G protein-coupled receptor 55. The Journal of Biological Chemistry. 288: 22481-92. PMID 23814062 DOI: 10.1074/Jbc.M113.456178  0.451
2012 Mallilankaraman K, Doonan P, Cárdenas C, Chandramoorthy HC, Müller M, Miller R, Hoffman NE, Gandhirajan RK, Molgó J, Birnbaum MJ, Rothberg BS, Mak DO, Foskett JK, Madesh M. MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival. Cell. 151: 630-44. PMID 23101630 DOI: 10.1016/J.Cell.2012.10.011  0.667
1994 Berkelman T, Garret-Engele P, Hoffman NE. The pacL gene of Synechococcus sp. strain PCC 7942 encodes a Ca(2+)-transporting ATPase. Journal of Bacteriology. 176: 4430-6. PMID 8021228 DOI: 10.1128/JB.176.14.4430-4436.1994  0.37
1993 Huang L, Berkelman T, Franklin AE, Hoffman NE. Characterization of a gene encoding a Ca(2+)-ATPase-like protein in the plastid envelope. Proceedings of the National Academy of Sciences of the United States of America. 90: 10066-70. PMID 8234257 DOI: 10.1073/PNAS.90.21.10066  0.3
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