Kenneth S. Zaret - Publications

Affiliations: 
Brown University, Providence, RI 
Area:
Molecular Biology, Biochemistry, Cell Biology

155 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Katsuda T, Sussman JH, Ito K, Katznelson A, Yuan S, Takenaka N, Li J, Merrell AJ, Cure H, Li Q, Rasool RU, Asangani IA, Zaret KS, Stanger BZ. Cellular reprogramming in vivo initiated by SOX4 pioneer factor activity. Nature Communications. 15: 1761. PMID 38409161 DOI: 10.1038/s41467-024-45939-z  0.435
2023 Barral A, Zaret KS. Pioneer factors: roles and their regulation in development. Trends in Genetics : Tig. PMID 37940484 DOI: 10.1016/j.tig.2023.10.007  0.431
2023 Pownall ME, Miao L, Vejnar CE, M'Saad O, Sherrard A, Frederick MA, Benitez MDJ, Boswell CW, Zaret KS, Bewersdorf J, Giraldez AJ. Chromatin expansion microscopy reveals nanoscale organization of transcription and chromatin. Science (New York, N.Y.). 381: 92-100. PMID 37410825 DOI: 10.1126/science.ade5308  0.326
2023 Lerner J, Katznelson A, Zhang J, Zaret KS. Different chromatin-scanning modes lead to targeting of compacted chromatin by pioneer factors FOXA1 and SOX2. Cell Reports. 42: 112748. PMID 37405916 DOI: 10.1016/j.celrep.2023.112748  0.356
2023 McCarthy RL, Zhang J, Zaret KS. Diverse heterochromatin states restricting cell identity and reprogramming. Trends in Biochemical Sciences. PMID 36990958 DOI: 10.1016/j.tibs.2023.02.007  0.397
2023 Katsuda T, Sussman J, Ito K, Katznelson A, Yuan S, Li J, Merrell AJ, Takenaka N, Cure H, Li Q, Rasool RU, Asangani IA, Zaret KS, Stanger BZ. Physiological reprogramming mediated by Sox4 pioneer factor activity. Biorxiv : the Preprint Server For Biology. PMID 36824858 DOI: 10.1101/2023.02.14.528556  0.423
2022 Frederick MA, Williamson KE, Fernandez Garcia M, Ferretti MB, McCarthy RL, Donahue G, Luzete Monteiro E, Takenaka N, Reynaga J, Kadoch C, Zaret KS. A pioneer factor locally opens compacted chromatin to enable targeted ATP-dependent nucleosome remodeling. Nature Structural & Molecular Biology. PMID 36536103 DOI: 10.1038/s41594-022-00886-5  0.753
2022 Luzete-Monteiro E, Zaret KS. Structures and consequences of pioneer factor binding to nucleosomes. Current Opinion in Structural Biology. 75: 102425. PMID 35863165 DOI: 10.1016/j.sbi.2022.102425  0.425
2022 Gong W, Das S, Sierra-Pagan JE, Skie E, Dsouza N, Larson TA, Garry MG, Luzete-Monteiro E, Zaret KS, Garry DJ. ETV2 functions as a pioneer factor to regulate and reprogram the endothelial lineage. Nature Cell Biology. 24: 672-684. PMID 35550615 DOI: 10.1038/s41556-022-00901-3  0.332
2022 Ito K, Zaret KS. Maintaining Transcriptional Specificity Through Mitosis. Annual Review of Genomics and Human Genetics. PMID 35440147 DOI: 10.1146/annurev-genom-121321-094603  0.392
2021 Reizel Y, Morgan A, Gao L, Schug J, Mukherjee S, García MF, Donahue G, Baur JA, Zaret KS, Kaestner KH. FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity. Developmental Cell. PMID 33636105 DOI: 10.1016/j.devcel.2021.02.005  0.372
2020 Zaret KS. Pioneer Transcription Factors Initiating Gene Network Changes. Annual Review of Genetics. PMID 32886547 DOI: 10.1146/Annurev-Genet-030220-015007  0.493
2020 Donovan PJ, Zaret KS. John D. Gearhart (1943-2020). Science (New York, N.Y.). 369: 628. PMID 32764057 DOI: 10.1126/Science.Abd6915  0.318
2020 Lerner J, Gomez-Garcia PA, McCarthy RL, Liu Z, Lakadamyali M, Zaret KS. Two-Parameter Mobility Assessments Discriminate Diverse Regulatory Factor Behaviors in Chromatin. Molecular Cell. PMID 32574554 DOI: 10.1016/J.Molcel.2020.05.036  0.431
2020 Iwafuchi M, Cuesta I, Donahue G, Takenaka N, Osipovich AB, Magnuson MA, Roder H, Seeholzer SH, Santisteban P, Zaret KS. Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones. Nature Genetics. PMID 32203463 DOI: 10.1038/S41588-020-0591-8  0.473
2019 Fernandez Garcia M, Moore CD, Schulz KN, Alberto O, Donague G, Harrison MM, Zhu H, Zaret KS. Structural Features of Transcription Factors Associating with Nucleosome Binding. Molecular Cell. PMID 31303471 DOI: 10.1016/J.Molcel.2019.06.009  0.756
2019 Nicetto D, Zaret KS. Role of H3K9me3 heterochromatin in cell identity establishment and maintenance. Current Opinion in Genetics & Development. 55: 1-10. PMID 31103921 DOI: 10.1016/J.Gde.2019.04.013  0.422
2019 McDaniel SL, Gibson TJ, Schulz KN, Fernandez Garcia M, Nevil M, Jain SU, Lewis PW, Zaret KS, Harrison MM. Continued Activity of the Pioneer Factor Zelda Is Required to Drive Zygotic Genome Activation. Molecular Cell. PMID 30797686 DOI: 10.1016/J.Molcel.2019.01.014  0.733
2019 Grindheim JM, Nicetto D, Donahue G, Zaret KS. PRC2 proteins EZH1 and EZH2 Regulate Timing of Postnatal Hepatocyte Maturation and Fibrosis by Repressing Gene Expression at Promoter Regions in Euchromatin in Mice. Gastroenterology. PMID 30689973 DOI: 10.1053/J.Gastro.2019.01.041  0.423
2019 Nicetto D, Donahue G, Jain T, Peng T, Sidoli S, Sheng L, Montavon T, Becker JS, Grindheim JM, Blahnik K, Garcia BA, Tan K, Bonasio R, Jenuwein T, Zaret KS. H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science (New York, N.Y.). PMID 30606806 DOI: 10.1126/Science.Aau0583  0.409
2019 Kim J, Zaret KS. Generation of Induced Pluripotent Stem Cell-Like Lines from Human Pancreatic Ductal Adenocarcinoma. Methods in Molecular Biology (Clifton, N.J.). 1882: 33-53. PMID 30378042 DOI: 10.1007/978-1-4939-8879-2_4  0.323
2019 King H, Zaret K. Decision letter: Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle Elife. DOI: 10.7554/Elife.50087.Sa1  0.409
2018 Fu K, Chronis C, Soufi A, Bonora G, Edwards M, Smale ST, Zaret KS, Plath K, Pellegrini M. Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming. Bmc Genomics. 19: 956. PMID 30577748 DOI: 10.1186/S12864-018-5326-1  0.388
2018 Palozola KC, Lerner J, Zaret KS. A changing paradigm of transcriptional memory propagation through mitosis. Nature Reviews. Molecular Cell Biology. PMID 30420736 DOI: 10.1038/S41580-018-0077-Z  0.487
2018 Kaeding KE, Zaret KS. Microsatellite enhancers can be targeted to impair tumorigenesis. Genes & Development. 32: 991-992. PMID 30068701 DOI: 10.1101/Gad.318105.118  0.316
2018 Zaret KS. The telomerase enzyme and liver renewal. Nature. 556: 181-182. PMID 29636575 DOI: 10.1038/D41586-018-02684-W  0.356
2018 Zaret KS. Pioneering the chromatin landscape. Nature Genetics. PMID 29374252 DOI: 10.1038/S41588-017-0038-Z  0.476
2018 Palozola KC, Liu H, Nicetto D, Zaret KS. Low-Level, Global Transcription during Mitosis and Dynamic Gene Reactivation during Mitotic Exit. Cold Spring Harbor Symposia On Quantitative Biology. PMID 29348325 DOI: 10.1101/Sqb.2017.82.034280  0.426
2017 Becker JS, McCarthy RL, Sidoli S, Donahue G, Kaeding KE, He Z, Lin S, Garcia BA, Zaret KS. Genomic and Proteomic Resolution of Heterochromatin and Its Restriction of Alternate Fate Genes. Molecular Cell. 68: 1023-1037.e15. PMID 29272703 DOI: 10.1016/J.Molcel.2017.11.030  0.448
2017 Palozola KC, Donahue G, Liu H, Grant GR, Becker JS, Cote A, Yu H, Raj A, Zaret KS. Mitotic transcription and waves of gene reactivation during mitotic exit. Science (New York, N.Y.). PMID 28912132 DOI: 10.1126/Science.Aal4671  0.437
2017 Zaret KS. Cell fate conversion: a chromatin remodeling checkpoint revealed. Cell Research. PMID 28361895 DOI: 10.1038/Cr.2017.44  0.416
2016 Bhat N, Park J, Zoghbi HY, Arthur JS, Zaret KS. The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development. Plos One. 11: e0166703. PMID 27973548 DOI: 10.1371/Journal.Pone.0166703  0.381
2016 Yokoyama Y, Zhu H, Lee JH, Kossenkov AV, Wu SY, Wickramasinghe JM, Yin X, Palozola KC, Gardini A, Showe LC, Zaret KS, Liu Q, Speicher D, Conejo-Garcia JR, Bradner JE, et al. BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer. Cancer Research. 76: 6320-6330. PMID 27803105 DOI: 10.1158/0008-5472.Can-16-0854  0.328
2016 Zaret KS, Lerner J, Iwafuchi-Doi M. Chromatin Scanning by Dynamic Binding of Pioneer Factors. Molecular Cell. 62: 665-7. PMID 27259199 DOI: 10.1016/J.Molcel.2016.05.024  0.466
2016 Iwafuchi-Doi M, Zaret KS. Cell fate control by pioneer transcription factors. Development (Cambridge, England). 143: 1833-7. PMID 27246709 DOI: 10.1242/Dev.133900  0.493
2016 Iwafuchi-Doi M, Donahue G, Kakumanu A, Watts JA, Mahony S, Pugh BF, Lee D, Kaestner KH, Zaret KS. The Pioneer Transcription Factor FoxA Maintains an Accessible Nucleosome Configuration at Enhancers for Tissue-Specific Gene Activation. Molecular Cell. 62: 79-91. PMID 27058788 DOI: 10.1016/J.Molcel.2016.03.001  0.527
2016 Zaret KS. From Endoderm to Liver Bud: Paradigms of Cell Type Specification and Tissue Morphogenesis. Current Topics in Developmental Biology. 117: 647-69. PMID 26970006 DOI: 10.1016/Bs.Ctdb.2015.12.015  0.443
2016 Braga Malta DF, Reticker-Flynn NE, da Silva CL, Cabral JM, Fleming HE, Zaret KS, Bhatia SN, Underhill GH. Extracellular matrix microarrays to study inductive signaling for endoderm specification. Acta Biomaterialia. 34: 30-40. PMID 26883775 DOI: 10.1016/J.Actbio.2016.02.014  0.394
2016 Zaret KS, Mango SE. Pioneer transcription factors, chromatin dynamics, and cell fate control. Current Opinion in Genetics & Development. 37: 76-81. PMID 26826681 DOI: 10.1016/J.Gde.2015.12.003  0.52
2016 Becker JS, Nicetto D, Zaret KS. H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes. Trends in Genetics : Tig. 32: 29-41. PMID 26675384 DOI: 10.1016/J.Tig.2015.11.001  0.485
2015 Hsu HT, Chen HM, Yang Z, Wang J, Lee NK, Burger A, Zaret K, Liu T, Levine E, Mango SE. Erratum for the Report “Recruitment of RNA polymerase II by the pioneer transcription factor PHA-4” Science. 350: 5928. PMID 26472915 DOI: 10.1126/Science.Aad5928  0.303
2015 Zaret KS. Regenerative biology: Maintaining liver mass. Nature. 524: 165-6. PMID 26245376 DOI: 10.1038/Nature15201  0.377
2015 Hsu HT, Chen HM, Yang Z, Wang J, Lee NK, Burger A, Zaret K, Liu T, Levine E, Mango SE. TRANSCRIPTION. Recruitment of RNA polymerase II by the pioneer transcription factor PHA-4. Science (New York, N.Y.). 348: 1372-6. PMID 26089518 DOI: 10.1126/Science.Aab1223  0.438
2015 Soufi A, Garcia MF, Jaroszewicz A, Osman N, Pellegrini M, Zaret KS. Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming. Cell. 161: 555-68. PMID 25892221 DOI: 10.1016/J.Cell.2015.03.017  0.494
2015 Shimbo T, Lavender C, Grimm SA, Doi MI, Henriques T, Cannady KR, Murphy KJ, Gilchrist DA, Burkholder A, Hayes JJ, Adelman K, Archer TK, Zaret KS, Wade PA. Abstract 2862: MBD3 regulates chromatin accessibility at active promoters Cancer Research. 75: 2862-2862. DOI: 10.1158/1538-7445.Am2015-2862  0.469
2014 Iwafuchi-Doi M, Zaret KS. Pioneer transcription factors in cell reprogramming. Genes & Development. 28: 2679-92. PMID 25512556 DOI: 10.1101/Gad.253443.114  0.535
2014 Xu CR, Li LC, Donahue G, Ying L, Zhang YW, Gadue P, Zaret KS. Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification. The Embo Journal. 33: 2157-70. PMID 25107471 DOI: 10.15252/Embj.201488671  0.415
2014 Bhatia SN, Underhill GH, Zaret KS, Fox IJ. Cell and tissue engineering for liver disease. Science Translational Medicine. 6: 245sr2. PMID 25031271 DOI: 10.1126/Scitranslmed.3005975  0.344
2014 Zaret KS. Genome reactivation after the silence in mitosis: recapitulating mechanisms of development? Developmental Cell. 29: 132-4. PMID 24780732 DOI: 10.1016/J.Devcel.2014.04.019  0.463
2014 Kim J, Zaret KS. Abstract B116: Modeling of early to invasive stages of pancreatic cancer progression with an iPSC-like line from human pancreatic ductal adenocarcinoma Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B116  0.311
2013 Kim J, Hoffman JP, Alpaugh RK, Rhim AD, Rhimm AD, Reichert M, Stanger BZ, Furth EE, Sepulveda AR, Yuan CX, Won KJ, Donahue G, Sands J, Gumbs AA, Zaret KS. An iPSC line from human pancreatic ductal adenocarcinoma undergoes early to invasive stages of pancreatic cancer progression. Cell Reports. 3: 2088-99. PMID 23791528 DOI: 10.1016/J.Celrep.2013.05.036  0.309
2013 Lagha M, Mayeuf-Louchart A, Chang T, Montarras D, Rocancourt D, Zalc A, Kormish J, Zaret KS, Buckingham ME, Relaix F. Itm2a is a Pax3 target gene, expressed at sites of skeletal muscle formation in vivo. Plos One. 8: e63143. PMID 23650549 DOI: 10.1371/Journal.Pone.0063143  0.378
2013 Soufi A, Zaret KS. Understanding impediments to cellular conversion to pluripotency by assessing the earliest events in ectopic transcription factor binding to the genome. Cell Cycle (Georgetown, Tex.). 12: 1487-91. PMID 23603987 DOI: 10.4161/Cc.24663  0.482
2013 Caravaca JM, Donahue G, Becker JS, He X, Vinson C, Zaret KS. Bookmarking by specific and nonspecific binding of FoxA1 pioneer factor to mitotic chromosomes. Genes & Development. 27: 251-60. PMID 23355396 DOI: 10.1186/1756-8935-6-S1-P94  0.486
2013 Iwafuchi-Doi M, Donahue G, Watts J, Cuesta I, Zaret KS. Pioneer transcription factor FoxA is positioned on hypersensitive nucleosomes at active enhancers Epigenetics & Chromatin. 6. DOI: 10.1186/1756-8935-6-S1-P30  0.504
2013 Zaret K, Palozola K, Caravaca JM. Activating the genome during development and exit from mitosis Epigenetics & Chromatin. 6: 1-1. DOI: 10.1186/1756-8935-6-S1-O35  0.532
2012 Soufi A, Donahue G, Zaret KS. Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome. Cell. 151: 994-1004. PMID 23159369 DOI: 10.1016/J.Cell.2012.09.045  0.48
2012 Serup P, Gustavsen C, Klein T, Potter LA, Lin R, Mullapudi N, Wandzioch E, Hines A, Davis A, Bruun C, Engberg N, Petersen DR, Peterslund JM, Macdonald RJ, Grapin-Botton A, ... ... Zaret KS, et al. Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice. Disease Models & Mechanisms. 5: 956-66. PMID 22888097 DOI: 10.1242/Dmm.009696  0.39
2012 Xu CR, Zaret KS. Chromatin "pre-pattern" and epigenetic modulation in the cell fate choice of liver over pancreas in the endoderm. Nucleus (Austin, Tex.). 3: 150-4. PMID 22555599 DOI: 10.4161/Nucl.19321  0.462
2012 Metzger DE, Gasperowicz M, Otto F, Cross JC, Gradwohl G, Zaret KS. The transcriptional co-repressor Grg3/Tle3 promotes pancreatic endocrine progenitor delamination and β-cell differentiation. Development (Cambridge, England). 139: 1447-56. PMID 22434868 DOI: 10.1242/Dev.072892  0.418
2012 Petersen DR, Gustavsen C, Lindskog SR, Magnuson MA, Zaret KS, Serup P. Engineering artificial signaling centers to polarize embryoid body differentiation. Stem Cells and Development. 21: 647-53. PMID 21958075 DOI: 10.1089/Scd.2011.0344  0.321
2012 Kim J, Zaret KS, Hoffman JP, Reichert M, Rhim AD, Stanger BZ, Gumbs A. Abstract B98: Induced pluripotent stem cells from pancreatic ductal adenocarcinoma can recapitulate early developmental stages of cancer. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B98  0.316
2011 Zaret KS, Carroll JS. Pioneer transcription factors: establishing competence for gene expression. Genes & Development. 25: 2227-41. PMID 22056668 DOI: 10.1101/Gad.176826.111  0.523
2011 Watts JA, Zhang C, Klein-Szanto AJ, Kormish JD, Fu J, Zhang MQ, Zaret KS. Study of FoxA pioneer factor at silent genes reveals Rfx-repressed enhancer at Cdx2 and a potential indicator of esophageal adenocarcinoma development. Plos Genetics. 7: e1002277. PMID 21935353 DOI: 10.1371/Journal.Pgen.1002277  0.462
2011 Xu CR, Cole PA, Meyers DJ, Kormish J, Dent S, Zaret KS. Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas. Science (New York, N.Y.). 332: 963-6. PMID 21596989 DOI: 10.1126/Science.1202845  0.471
2011 Metzger D, Gasperowicz M, Otto F, Cross J, Zaret K. Grg3 corepressor is required for the differentiation of secondary transition endocrine cells in the embryonic pancreas Developmental Biology. 356: 189-190. DOI: 10.1016/J.Ydbio.2011.05.240  0.328
2010 Zaret KS, Caravaca JM, Tulin A, Sekiya T. Nuclear mobility and mitotic chromosome binding similarities between pioneer transcription factor FoxA and linker histone H1 Cold Spring Harbor Symposia On Quantitative Biology. 75: 219-226. PMID 21502411 DOI: 10.1101/Sqb.2010.75.061  0.5
2010 Santisteban P, Recacha P, Metzger DE, Zaret KS. Dynamic expression of Groucho-related genes Grg1 and Grg3 in foregut endoderm and antagonism of differentiation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 980-6. PMID 20108349 DOI: 10.1002/Dvdy.22217  0.443
2009 Xu J, Watts JA, Pope SD, Gadue P, Kamps M, Plath K, Zaret KS, Smale ST. Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Genes & Development. 23: 2824-38. PMID 20008934 DOI: 10.1101/Gad.1861209  0.482
2009 Wandzioch E, Zaret KS. Dynamic signaling network for the specification of embryonic pancreas and liver progenitors. Science (New York, N.Y.). 324: 1707-10. PMID 19556507 DOI: 10.1126/Science.1174497  0.419
2009 Gadue P, Gouon-Evans V, Cheng X, Wandzioch E, Zaret KS, Grompe M, Streeter PR, Keller GM. Generation of monoclonal antibodies specific for cell surface molecules expressed on early mouse endoderm. Stem Cells (Dayton, Ohio). 27: 2103-13. PMID 19522011 DOI: 10.1002/Stem.147  0.315
2009 Zaret KS. Using small molecules to great effect in stem cell differentiation. Cell Stem Cell. 4: 373-4. PMID 19427285 DOI: 10.1016/J.Stem.2009.04.012  0.328
2009 Sekiya T, Muthurajan UM, Luger K, Tulin AV, Zaret KS. Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA. Genes & Development. 23: 804-9. PMID 19339686 DOI: 10.1101/Gad.1775509  0.466
2009 Cortellino S, Wang C, Wang B, Bassi MR, Caretti E, Champeval D, Calmont A, Jarnik M, Burch J, Zaret KS, Larue L, Bellacosa A. Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4. Developmental Biology. 325: 225-37. PMID 19000668 DOI: 10.1016/J.Ydbio.2008.10.020  0.308
2009 Bort R, Zaret KS. Embryonic Development of the Liver The Liver: Biology and Pathobiology: Fifth Edition. 17-25. DOI: 10.1002/9780470747919.Ch2  0.335
2008 Zaret KS, Grompe M. Generation and regeneration of cells of the liver and pancreas. Science (New York, N.Y.). 322: 1490-4. PMID 19056973 DOI: 10.1126/Science.1161431  0.435
2008 Zaret KS, Watts J, Xu J, Wandzioch E, Smale ST, Sekiya T. Pioneer factors, genetic competence, and inductive signaling: programming liver and pancreas progenitors from the endoderm. Cold Spring Harbor Symposia On Quantitative Biology. 73: 119-26. PMID 19028990 DOI: 10.1101/Sqb.2008.73.040  0.522
2008 Lagha M, Kormish JD, Rocancourt D, Manceau M, Epstein JA, Zaret KS, Relaix F, Buckingham ME. Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program. Genes & Development. 22: 1828-37. PMID 18593883 DOI: 10.1101/Gad.477908  0.457
2008 Zaret KS. Genetic programming of liver and pancreas progenitors: lessons for stem-cell differentiation. Nature Reviews. Genetics. 9: 329-40. PMID 18398419 DOI: 10.1038/Nrg2318  0.389
2008 Wandzioch E, Zaret KS. Endoderm cell signaling networks during liver and pancreas specification Developmental Biology. 319: 585. DOI: 10.1016/J.Ydbio.2008.05.420  0.331
2008 Freedman-Cass DA, Zaret KS. Endothelial responsiveness of Ptf1a and other genes in liver and dorsal pancreas progenitors Developmental Biology. 319: 573. DOI: 10.1016/J.Ydbio.2008.05.375  0.325
2007 Freedman DA, Kashima Y, Zaret KS. Endothelial cell promotion of early liver and pancreas development. Novartis Foundation Symposium. 283: 207-16; discussion 2. PMID 18300424 DOI: 10.1002/9780470319413.Ch16  0.387
2007 Sekiya T, Zaret KS. Repression by Groucho/TLE/Grg proteins: genomic site recruitment generates compacted chromatin in vitro and impairs activator binding in vivo. Molecular Cell. 28: 291-303. PMID 17964267 DOI: 10.1016/J.Molcel.2007.10.002  0.469
2007 Cuesta I, Zaret KS, Santisteban P. The forkhead factor FoxE1 binds to the thyroperoxidase promoter during thyroid cell differentiation and modifies compacted chromatin structure. Molecular and Cellular Biology. 27: 7302-14. PMID 17709379 DOI: 10.1128/Mcb.00758-07  0.478
2007 Xu J, Pope SD, Jazirehi AR, Attema JL, Papathanasiou P, Watts JA, Zaret KS, Weissman IL, Smale ST. Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 12377-82. PMID 17640912 DOI: 10.1073/Pnas.0704579104  0.506
2007 Wiebe PO, Kormish JD, Roper VT, Fujitani Y, Alston NI, Zaret KS, Wright CV, Stein RW, Gannon M. Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression. Molecular and Cellular Biology. 27: 4093-104. PMID 17403901 DOI: 10.1128/Mcb.01978-06  0.402
2007 Cirillo LA, Zaret KS. Specific interactions of the wing domains of FOXA1 transcription factor with DNA. Journal of Molecular Biology. 366: 720-4. PMID 17189638 DOI: 10.1016/J.Jmb.2006.11.087  0.399
2007 Wiebe PO, Kormish JD, Fujitani Y, Zaret KS, Wright CV, Stein RW, Gannon. Ptf1a binds to Area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression Developmental Biology. 306: 353-354. DOI: 10.1016/J.Ydbio.2007.03.225  0.362
2006 Calmont A, Wandzioch E, Tremblay KD, Minowada G, Kaestner KH, Martin GR, Zaret KS. An FGF response pathway that mediates hepatic gene induction in embryonic endoderm cells. Developmental Cell. 11: 339-48. PMID 16950125 DOI: 10.1016/J.Devcel.2006.06.015  0.389
2006 Zaret KS. Stability and evolution of transcriptional regulatory networks. Molecular Systems Biology. 2: 2006.0021. PMID 16738566 DOI: 10.1038/Msb4100066  0.492
2006 West S, Zaret K, Proudfoot NJ. Transcriptional termination sequences in the mouse serum albumin gene Rna. 12: 655-665. PMID 16581808 DOI: 10.1261/Rna.2232406  0.385
2006 Jacquemin P, Yoshitomi H, Kashima Y, Rousseau GG, Lemaigre FP, Zaret KS. An endothelial-mesenchymal relay pathway regulates early phases of pancreas development. Developmental Biology. 290: 189-99. PMID 16386727 DOI: 10.1016/J.Ydbio.2005.11.023  0.405
2006 Bort R, Signore M, Tremblay K, Martinez Barbera JP, Zaret KS. Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development. Developmental Biology. 290: 44-56. PMID 16364283 DOI: 10.1016/J.Ydbio.2005.11.006  0.416
2005 Zaret K. Micrococcal Nuclease Analysis of Chromatin Structure Current Protocols in Molecular Biology. 69. PMID 18265356 DOI: 10.1002/0471142727.Mb2101S69  0.381
2005 Tremblay KD, Zaret KS. Distinct populations of endoderm cells converge to generate the embryonic liver bud and ventral foregut tissues. Developmental Biology. 280: 87-99. PMID 15766750 DOI: 10.1016/J.Ydbio.2005.01.003  0.365
2005 Holmqvist PH, Belikov S, Zaret KS, Wrange O. FoxA1 binding to the MMTV LTR modulates chromatin structure and transcription. Experimental Cell Research. 304: 593-603. PMID 15748903 DOI: 10.1016/J.Yexcr.2004.12.002  0.46
2004 Lemaigre F, Zaret KS. Liver development update: new embryo models, cell lineage control, and morphogenesis. Current Opinion in Genetics & Development. 14: 582-90. PMID 15380251 DOI: 10.1016/J.Gde.2004.08.004  0.425
2004 Cirillo L, Zaret K. Developmental biology. A linker histone restricts muscle development. Science (New York, N.Y.). 304: 1607-9. PMID 15192207 DOI: 10.1126/Science.1099577  0.373
2004 Taganov KD, Cuesta I, Daniel R, Cirillo LA, Katz RA, Zaret KS, Skalka AM. Integrase-specific enhancement and suppression of retroviral DNA integration by compacted chromatin structure in vitro. Journal of Virology. 78: 5848-55. PMID 15140982 DOI: 10.1128/Jvi.78.11.5848-5855.2004  0.397
2004 Chaya D, Zaret KS. Sequential chromatin immunoprecipitation from animal tissues. Methods in Enzymology. 376: 361-72. PMID 14975318 DOI: 10.1016/S0076-6879(03)76024-8  0.435
2004 Cirillo LA, Zaret KS. Preparation of defined mononucleosomes, dinucleosomes, and nucleosome arrays in vitro and analysis of transcription factor binding. Methods in Enzymology. 375: 131-58. PMID 14870664 DOI: 10.1016/S0076-6879(03)75009-5  0.472
2004 Bort R, Martinez-Barbera JP, Beddington RS, Zaret KS. Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas. Development (Cambridge, England). 131: 797-806. PMID 14736744 DOI: 10.1242/Dev.00965  0.427
2004 Yoshitomi H, Zaret KS. Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a. Development (Cambridge, England). 131: 807-17. PMID 14736742 DOI: 10.1242/Dev.00960  0.411
2003 Istomina NE, Shushanov SS, Springhetti EM, Karpov VL, Krasheninnikov IA, Stevens K, Zaret KS, Singh PB, Grigoryev SA. Insulation of the chicken beta-globin chromosomal domain from a chromatin-condensing protein, MENT. Molecular and Cellular Biology. 23: 6455-68. PMID 12944473 DOI: 10.1128/Mcb.23.18.6455-6468.2003  0.404
2003 Parviz F, Matullo C, Garrison WD, Savatski L, Adamson JW, Ning G, Kaestner KH, Rossi JM, Zaret KS, Duncan SA. Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis. Nature Genetics. 34: 292-6. PMID 12808453 DOI: 10.1038/Ng1175  0.7
2003 Guo Y, Chan R, Ramsey H, Li W, Xie X, Shelley WC, Martinez-Barbera JP, Bort B, Zaret K, Yoder M, Hromas R. The homeoprotein Hex is required for hemangioblast differentiation. Blood. 102: 2428-35. PMID 12791650 DOI: 10.1182/Blood-2003-02-0634  0.398
2003 Deng Z, Chen CJ, Chamberlin M, Lu F, Blobel GA, Speicher D, Cirillo LA, Zaret KS, Lieberman PM. The CBP bromodomain and nucleosome targeting are required for Zta-directed nucleosome acetylation and transcription activation. Molecular and Cellular Biology. 23: 2633-44. PMID 12665567 DOI: 10.1128/Mcb.23.8.2633-2644.2003  0.445
2003 Mohn D, Chen SW, Dias DC, Weinstein DC, Dyer MA, Sahr K, Ducker CE, Zahradka E, Keller G, Zaret KS, Gudas LJ, Baron MH. Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 226: 446-59. PMID 12619131 DOI: 10.1002/Dvdy.10263  0.407
2003 Zaret KS. MOD special issue on the molecular mechanisms of liver and pancreas development Mechanisms of Development. 120: 3. DOI: 10.1016/S0925-4773(02)00326-X  0.306
2002 Bort R, Zaret K. Paths to the pancreas Nature Genetics. 32: 85-86. PMID 12205472 DOI: 10.1038/Ng0902-85  0.452
2002 Lin X, Jung J, Kang D, Xu B, Zaret KS, Zoghbi H. Prenylcysteine carboxylmethyltransferase is essential for the earliest stages of liver development in mice. Gastroenterology. 123: 345-51. PMID 12105862 DOI: 10.1053/Gast.2002.34279  0.584
2002 Zaret KS. Regulatory phases of early liver development: paradigms of organogenesis. Nature Reviews. Genetics. 3: 499-512. PMID 12094228 DOI: 10.1038/Nrg837  0.416
2002 Cirillo LA, Lin FR, Cuesta I, Friedman D, Jarnik M, Zaret KS. Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4. Molecular Cell. 9: 279-89. PMID 11864602 DOI: 10.1016/S1097-2765(02)00459-8  0.516
2001 Matsumoto K, Yoshitomi H, Rossant J, Zaret KS. Liver organogenesis promoted by endothelial cells prior to vascular function Science. 294: 559-563. PMID 11577199 DOI: 10.1126/Science.1063889  0.363
2001 Chaya D, Hayamizu T, Bustin M, Zaret KS. Transcription Factor FoxA (HNF3) on a Nucleosome at an Enhancer Complex in Liver Chromatin Journal of Biological Chemistry. 276: 44385-44389. PMID 11571307 DOI: 10.1074/Jbc.M108214200  0.491
2001 Zaret KS. Hepatocyte differentiation: From the endoderm and beyond Current Opinion in Genetics and Development. 11: 568-574. PMID 11532400 DOI: 10.1016/S0959-437X(00)00234-3  0.389
2001 Rossi JM, Dunn NR, Hogan BL, Zaret KS. Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. Genes & Development. 15: 1998-2009. PMID 11485993 DOI: 10.1101/Gad.904601  0.715
2001 Deutsch G, Jung J, Zheng M, Lóra J, Zaret KS. A bipotential precursor population for pancreas and liver within the embryonic endoderm. Development (Cambridge, England). 128: 871-81. PMID 11222142  0.605
2000 Bossard P, Zaret KS. Repressive and restrictive mesodermal interactions with gut endoderm: Possible relation to Meckel's Diverticulum Development. 127: 4915-4923. PMID 11044405  0.362
2000 Stevens K, Cirillo L, Zaret KS. Creating temperature-sensitive winged helix transcription factors. Amino acids that stabilize the DNA binding domain of HNF3 Journal of Biological Chemistry. 275: 30471-30477. PMID 10896667 DOI: 10.1074/Jbc.M004891200  0.405
2000 Zaret KS. Liver specification and early morphogenesis Mechanisms of Development. 92: 83-88. PMID 10704889 DOI: 10.1016/S0925-4773(99)00326-3  0.407
1999 Cirillo LA, Zaret KS. An early developmental transcription factor complex that is more stable on nucleosome core particles than on free DNA Molecular Cell. 4: 961-969. PMID 10635321 DOI: 10.1016/S1097-2765(00)80225-7  0.506
1999 Jung J, Zheng M, Goldfarb M, Zaret KS. Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science (New York, N.Y.). 284: 1998-2003. PMID 10373120 DOI: 10.1126/Science.284.5422.1998  0.612
1999 Zaret KS. In vivo analysis of chromatin structure Methods in Enzymology. 304: 612-626. PMID 10372385 DOI: 10.1016/S0076-6879(99)04036-7  0.366
1999 Zaret K. Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins. Developmental Biology. 209: 1-10. PMID 10208738 DOI: 10.1006/Dbio.1999.9228  0.42
1998 Bossard P, Zaret KS. GATA transcription factors as potentiators of gut endoderm differentiation Development. 125: 4909-4917. PMID 9811575  0.437
1998 Zaret K. Early liver differentiation: genetic potentiation and multilevel growth control. Current Opinion in Genetics & Development. 8: 526-31. PMID 9794819 DOI: 10.1016/S0959-437X(98)80006-3  0.479
1998 Lora JM, Rowader KE, Soares L, Giancotti F, Zaret KS. Alpha3beta1-integrin as a critical mediator of the hepatic differentiation response to the extracellular matrix. Hepatology (Baltimore, Md.). 28: 1095-104. PMID 9755248 DOI: 10.1002/Hep.510280426  0.378
1998 Lodmell AG, Jung J, Zaret KS. Chromatin structure and functional analysis of the mouse HNF3alpha gene. Gene. 214: 167-76. PMID 9651517 DOI: 10.1016/S0378-1119(98)00198-X  0.665
1998 Cirillo LA, McPherson CE, Bossard P, Stevens K, Cherian S, Shim EY, Clark KL, Burley SK, Zaret KS. Binding of the winged-helix transcription factor HNF3 to a linker histone site on the nucleosome. The Embo Journal. 17: 244-54. PMID 9427758 DOI: 10.1093/Emboj/17.1.244  0.478
1998 Shim EY, Woodcock C, Zaret KS. Nucleosome positioning by the winged helix transcription factor HNF3. Genes & Development. 12: 5-10. PMID 9420326 DOI: 10.1101/Gad.12.1.5  0.461
1997 Bossard P, McPherson CE, Zaret KS. In vivo footprinting with limiting amounts of embryo tissues: A role for C/EBPβ in early hepatic development Methods: a Companion to Methods in Enzymology. 11: 180-188. PMID 8993030 DOI: 10.1006/Meth.1996.0404  0.463
1996 Zaret KS. Molecular genetics of early liver development Annual Review of Physiology. 58: 231-251. PMID 8815794 DOI: 10.1146/Annurev.Ph.58.030196.001311  0.412
1996 Gualdi R, Bossard P, Zheng M, Hamada Y, Coleman JR, Zaret KS. Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control. Genes & Development. 10: 1670-82. PMID 8682297 DOI: 10.1101/Gad.10.13.1670  0.516
1996 McPherson CE, Horowitz R, Woodcock CL, Jiang C, Zaret KS. Nucleosome positioning properties of the albumin transcriptional enhancer. Nucleic Acids Research. 24: 397-404. PMID 8602349 DOI: 10.1093/Nar/24.3.397  0.469
1995 Zaret KS, Stevens K. Expression of a Highly Unstable and Insoluble Transcription Factor inEscherichia coli:Purification and Characterization of thefork headHomolog Hnf3α Protein Expression and Purification. 6: 821-825. PMID 8746635 DOI: 10.1006/Prep.1995.0014  0.398
1995 Zaret KS. Nucleoprotein architecture of the albumin transcriptional enhancer Seminars in Cell and Developmental Biology. 6: 209-218. PMID 8562913 DOI: 10.1006/Scel.1995.0029  0.46
1995 Connelly S, Smith TA, Dhir G, Gardner JM, Mehaffey MG, Zaret KS, McClelland A, Kaleko M. In vivo gene delivery and expression of physiological levels of functional human factor VIII in mice. Human Gene Therapy. 6: 185-93. PMID 7537539 DOI: 10.1089/Hum.1995.6.2-185  0.315
1994 Zaret K. Genes that control the formation of the liver. Hepatology (Baltimore, Md.). 19: 794-6. PMID 8119710 DOI: 10.1002/Hep.1840190339  0.399
1993 Jackson DA, Rowader KE, Stevens K, Jiang C, Milos P, Zaret KS. Modulation of liver-specific transcription by interactions between hepatocyte nuclear factor 3 and nuclear factor 1 binding DNA in close apposition Molecular and Cellular Biology. 13: 2401-2410. PMID 8455618 DOI: 10.1128/Mcb.13.4.2401  0.49
1993 Rollier A, DiPersio CM, Cereghini S, Stevens K, Tronche F, Zaret K, Weiss MC. Regulation of albumin gene expression in hepatoma cells of fetal phenotype: dominant inhibition of HNF1 function and role of ubiquitous transcription factors. Molecular Biology of the Cell. 4: 59-69. PMID 8443410 DOI: 10.1091/Mbc.4.1.59  0.499
1993 McPherson CE, Shim EY, Friedman DS, Zaret KS. An active tissue-specific enhancer and bound transcription factors existing in a precisely positioned nucleosomal array Cell. 75: 387-398. PMID 8402920 DOI: 10.1016/0092-8674(93)80079-T  0.507
1993 Ang SL, Wierda A, Wong D, Stevens KA, Cascio S, Rossant J, Zaret KS. The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins. Development (Cambridge, England). 119: 1301-15. PMID 8306889  0.322
1992 Zaret KS. The touch that hepatocytes seem to like Hepatology. 15: 1204-1205. PMID 1592357 DOI: 10.1002/Hep.1840150636  0.359
1992 Milos PM, Zaret KS. A ubiquitous factor is required for C/EBP-related proteins to form stable transcription complexes on an albumin promoter segment in vitro Genes and Development. 6: 991-1004. PMID 1592265 DOI: 10.1101/Gad.6.6.991  0.44
1992 Zaret KS, Milos P, Lia M, Bali D, Gluecksohn-Waelsch S. Selective loss of a DNase I hypersensitive site upstream of the tyrosine aminotransferase gene in mice homozygous for lethal albino deletions Proceedings of the National Academy of Sciences of the United States of America. 89: 6540-6544. PMID 1378630 DOI: 10.1073/Pnas.89.14.6540  0.416
1991 Liu JK, DiPersio CM, Zaret KS. Extracellular signals that regulate liver transcription factors during hepatic differentiation in vitro. Molecular and Cellular Biology. 11: 773-84. PMID 1990282 DOI: 10.1128/Mcb.11.2.773  0.503
1991 DiPersio CM, Jackson DA, Zaret KS. The extracellular matrix coordinately modulates liver transcription factors and hepatocyte morphology. Molecular and Cellular Biology. 11: 4405-14. PMID 1875930 DOI: 10.1128/Mcb.11.9.4405  0.485
1990 Zaret KS, Liu JK, DiPersio CM. Site-directed mutagenesis reveals a liver transcription factor essential for the albumin transcriptional enhancer. Proceedings of the National Academy of Sciences of the United States of America. 87: 5469-73. PMID 2371282 DOI: 10.1073/Pnas.87.14.5469  0.466
1990 Zaret KS, Stevens KA. Selection and analysis of galactose metabolic pathway variants of a mouse liver cell line. Molecular and Cellular Biology. 10: 4582-9. PMID 2167434 DOI: 10.1128/Mcb.10.9.4582  0.344
1988 Liu JK, Bergman Y, Zaret KS. The mouse albumin promoter and a distal upstream site are simultaneously DNase I hypersensitive in liver chromatin and bind similar liver-abundant factors in vitro Genes &Amp; Development. 2: 528-541. PMID 3384331 DOI: 10.1101/Gad.2.5.528  0.49
1988 Zaret KS, DiPersio CM, Jackson DA, Montigny WJ, Weinstat DL. Conditional enhancement of liver-specific gene transcription. Proceedings of the National Academy of Sciences of the United States of America. 85: 9076-80. PMID 3194409 DOI: 10.1073/Pnas.85.23.9076  0.449
1984 Zaret KS, Yamamoto KR. Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element Cell. 38: 29-38. PMID 6088072 DOI: 10.1016/0092-8674(84)90523-3  0.435
1984 Zaret KS, Sherman F. Mutationally altered 3′ ends of yeast CYC1 mRNA affect transcript stability and translational efficiency Journal of Molecular Biology. 177: 107-135. PMID 6086937 DOI: 10.1016/0022-2836(84)90060-3  0.322
1982 Zaret KS, Sherman F. DNA sequence required for efficient transcription termination in yeast Cell. 28: 563-573. PMID 6280875 DOI: 10.1016/0092-8674(82)90211-2  0.37
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