Daniel Andrew Beard, Ph.D. - Publications

Affiliations: 
Molecular and Integrative Physiology University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Nonequilibrium thermodynamics in biochemical networks, Mass transport and microvascular exchange in physiological systems, Physiological and pathophysiological regulation of metabolism, Biophysics of supramolecular complexes

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Jones E, Hummel SL, Cameron DM, Beard DA, Carlson BE. Two Distinct Classes of Heart Failure with Preserved Ejection Fraction Emerge from Analysis of Standard Clinical Measures using Mechanistic Models of the Cardiovascular System The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06305  0.309
2020 Lopez R, Gao X, Marzban B, Lauinger E, Bergh FVd, Beard DA. Impaired Myocardial Energetics Contributes to Mechanical Dysfunction in Decompensated Failing Hearts Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.2526  0.304
2019 Gao X, Jakovljevic DG, Beard DA. Cardiac Metabolic Limitations Contribute to Diminished Performance of the Heart in Aging. Biophysical Journal. PMID 31395314 DOI: 10.1016/J.Bpj.2019.06.026  0.348
2019 Jones E, Cameron DM, Beard DA, Hummel SL, Carlson BE. Cardiovascular System Model-Based Phenotyping of Heart Failure with Preserved Ejection Fraction Journal of Cardiac Failure. 25. DOI: 10.1016/J.Cardfail.2019.07.092  0.382
2018 Beard DA. Assessing the Validity and Utility of the Guyton Model of Arterial Blood Pressure Control. Hypertension (Dallas, Tex. : 1979). 72: 1272-1273. PMID 30571241 DOI: 10.1161/Hypertensionaha.118.11998  0.322
2018 Kelly RA, Leedale J, Harrell A, Beard DA, Randle LE, Chadwick AE, Webb SD. Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture. Plos One. 13: e0207803. PMID 30496306 DOI: 10.1371/Journal.Pone.0207803  0.344
2018 Kosinski SA, Carlson BE, Hummel SL, Brook RD, Beard DA. Computational Model-Based Assessment of Baroreflex Function from Response to Valsalva Maneuver. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 30236047 DOI: 10.1152/Japplphysiol.00095.2018  0.36
2018 Pewowaruk RJ, Philip JL, Tewari SG, Chen CS, Nyaeme MS, Wang Z, Tabima DM, Baker AJ, Beard DA, Chesler NC. Multiscale Computational Analysis of Right Ventricular Mechanoenergetics. Journal of Biomechanical Engineering. 140. PMID 30003251 DOI: 10.1115/1.4040044  0.703
2018 Philip JL, Pewowaruk RJ, Chen CS, Tabima DM, Beard DA, Baker AJ, Chesler NC. Impaired Myofilament Contraction Drives Right Ventricular Failure Secondary to Pressure Overload: Model Simulations, Experimental Validation, and Treatment Predictions. Frontiers in Physiology. 9: 731. PMID 29997518 DOI: 10.3389/Fphys.2018.00731  0.392
2018 Moxley MA, Vinnakota KC, Bazil JN, Qi NR, Beard DA. Systems-level computational modeling demonstrates fuel selection switching in high capacity running and low capacity running rats. Plos Computational Biology. 14: e1005982. PMID 29474500 DOI: 10.1371/Journal.Pcbi.1005982  0.318
2018 Lopez R, Gao X, Van den Bergh F, Dasika S, Beard D. Quantifying the Contribution of Cardiomyocyte Metabolic Dysfunction to the Heart Mechanical Function Biophysical Journal. 114: 499a. DOI: 10.1016/J.Bpj.2017.11.2730  0.316
2017 Bakermans AJ, Bazil JN, Nederveen AJ, Strijkers GJ, Boekholdt SM, Beard DA, Jeneson JAL. Human Cardiac 31P-MR Spectroscopy at 3 Tesla Cannot Detect Failing Myocardial Energy Homeostasis during Exercise. Frontiers in Physiology. 8: 939. PMID 29230178 DOI: 10.3389/Fphys.2017.00939  0.314
2017 Thiagarajan R, Alavi A, Podichetty JT, Bazil JN, Beard DA. The feasibility of genome-scale biological network inference using Graphics Processing Units. Algorithms For Molecular Biology : Amb. 12: 8. PMID 28344638 DOI: 10.1186/S13015-017-0100-5  0.301
2017 Liu A, Philip J, Vinnakota KC, Van den Bergh F, Tabima DM, Hacker T, Beard DA, Chesler NC. Estrogen maintains mitochondrial content and function in the right ventricle of rats with pulmonary hypertension. Physiological Reports. 5. PMID 28320896 DOI: 10.14814/Phy2.13157  0.303
2017 Dasika SK, Kandel SM, Beard DA. Regulation of Carbon Substrate Utilization by Cardiac Mitochondria Biophysical Journal. 112: 131a. DOI: 10.1016/J.Bpj.2016.11.727  0.342
2016 Tewari SG, Bugenhagen SM, Vinnakota KC, Rice JJ, Janssen PM, Beard DA. Influence of metabolic dysfunction on cardiac mechanics in decompensated hypertrophy and heart failure. Journal of Molecular and Cellular Cardiology. PMID 27085901 DOI: 10.1016/J.Yjmcc.2016.04.003  0.774
2016 Vinnakota KC, Cha CY, Rorsman P, Balaban RS, La Gerche A, Wade-Martins R, Beard DA, Jeneson JA. Improving the physiological realism of experimental models. Interface Focus. 6: 20150076. PMID 27051507 DOI: 10.1098/Rsfs.2015.0076  0.343
2016 Pradhan RK, Feigl EO, Gorman MW, Brengelmann GL, Beard DA. Open-Loop (Feed-Forward) and Feedback Control of Coronary Blood Flow during Exercise Cardiac Pacing and Pressure Changes. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00663.2015. PMID 27037372 DOI: 10.1152/Ajpheart.00663.2015  0.595
2016 Vinnakota KC, Bazil JN, Van den Bergh F, Wiseman RW, Beard DA. Feedback Regulation and Time Hierarchy of Oxidative Phosphorylation in Cardiac Mitochondria. Biophysical Journal. 110: 972-80. PMID 26910434 DOI: 10.1016/J.Bpj.2016.01.003  0.317
2016 Bazil JN, Beard DA, Vinnakota KC. Catalytic Coupling of Oxidative Phosphorylation, ATP Demand, and Reactive Oxygen Species Generation. Biophysical Journal. 110: 962-71. PMID 26910433 DOI: 10.1016/J.Bpj.2015.09.036  0.383
2016 Vinnakota KC, Singhal A, Van den Bergh F, Bagher-Oskouei M, Wiseman RW, Beard DA. Open-Loop Control of Oxidative Phosphorylation in Skeletal and Cardiac Muscle Mitochondria by Ca(2.). Biophysical Journal. 110: 954-61. PMID 26910432 DOI: 10.1016/J.Bpj.2015.12.018  0.302
2016 Lee P, Carlson BE, Chesler N, Olufsen MS, Qureshi MU, Smith NP, Sochi T, Beard DA. Heterogeneous mechanics of the mouse pulmonary arterial network. Biomechanics and Modeling in Mechanobiology. PMID 26792789 DOI: 10.1007/S10237-015-0757-Y  0.357
2016 Bassingthwaighte JB, Raymond GM, Dash RK, Beard DA, Nolan M. The Pathway for Oxygen: Tutorial Modelling on Oxygen Transport from Air to Mitochondrion : The Pathway for Oxygen. Advances in Experimental Medicine and Biology. 876: 103-10. PMID 26782201 DOI: 10.1007/978-1-4939-3023-4_13  0.535
2015 Moxley MA, Beard DA, Bazil JN. Global Kinetic Analysis of Mammalian E3 Reveals pH-dependent NAD+/NADH Regulation, Physiological Kinetic Reversibility, and Catalytic Optimum. The Journal of Biological Chemistry. PMID 26644471 DOI: 10.1074/Jbc.M115.676619  0.332
2015 Bugenhagen SM, Beard DA. Computational analysis of the regulation of Ca(2+) dynamics in rat ventricular myocytes. Physical Biology. 12: 056008. PMID 26358004 DOI: 10.1088/1478-3975/12/5/056008  0.76
2015 Pannala VR, Beard DA, Dash RK. Letter to the Editor: Mitochondrial cytochrome c oxidase: mechanism of action and role in regulating oxidative phosphorylation. Journal of Applied Physiology (Bethesda, Md. : 1985). 119: 157. PMID 26177971 DOI: 10.1152/Japplphysiol.00290.2015  0.315
2015 Tewari SG, Bugenhagen SM, Palmer BM, Beard DA. Dynamics of cross-bridge cycling, ATP hydrolysis, force generation, and deformation in cardiac muscle. Journal of Molecular and Cellular Cardiology. PMID 25681584 DOI: 10.1016/J.Yjmcc.2015.02.006  0.773
2015 Dasika SK, Vinnakota KC, Beard DA. Characterization of the kinetics of cardiac cytosolic malate dehydrogenase and comparative analysis of cytosolic and mitochondrial isoforms. Biophysical Journal. 108: 420-30. PMID 25606689 DOI: 10.1016/J.Bpj.2014.11.3466  0.328
2015 Dasika SK, Vinnakota KC, Beard DA. Determination of the catalytic mechanism for mitochondrial malate dehydrogenase. Biophysical Journal. 108: 408-19. PMID 25606688 DOI: 10.1016/J.Bpj.2014.11.3467  0.306
2015 Tewari S, Bugenhagen S, Palmer B, Beard D. Computational Model of Cross-Bridge Cycling and Force Generation to Explain the Effect of Metabolites on Cardiac Muscle Mechanics Biophysical Journal. 108: 444a. DOI: 10.1016/J.Bpj.2014.11.2425  0.775
2015 Beard DA. The Emergence of Heart Failure as a Consequence of Myocardial Metabolic Dysfunction Biophysical Journal. 108: 33a. DOI: 10.1016/J.Bpj.2014.11.207  0.361
2014 Tewari SG, Zhou Y, Otto BJ, Dash RK, Kwok WM, Beard DA. Markov chain Monte Carlo based analysis of post-translationally modified VDAC gating kinetics. Frontiers in Physiology. 5: 513. PMID 25628567 DOI: 10.3389/Fphys.2014.00513  0.718
2014 Moxley MA, Beard DA, Bazil JN. A pH-dependent kinetic model of dihydrolipoamide dehydrogenase from multiple organisms. Biophysical Journal. 107: 2993-3007. PMID 25517164 DOI: 10.1016/J.Bpj.2014.09.025  0.329
2014 Pettersen KH, Bugenhagen SM, Nauman J, Beard DA, Omholt SW. Arterial stiffening provides sufficient explanation for primary hypertension. Plos Computational Biology. 10: e1003634. PMID 24853828 DOI: 10.1371/Journal.Pcbi.1003634  0.768
2013 Beard DA, Pettersen KH, Carlson BE, Omholt SW, Bugenhagen SM. A computational analysis of the long-term regulation of arterial pressure. F1000research. 2: 208. PMID 24555102 DOI: 10.12688/F1000Research.2-208.V2  0.771
2013 Tewari SG, Bugenhagen SM, Wang Z, Schreier DA, Carlson BE, Chesler NC, Beard DA. Analysis of cardiovascular dynamics in pulmonary hypertensive C57BL6/J mice. Frontiers in Physiology. 4: 355. PMID 24376421 DOI: 10.3389/Fphys.2013.00355  0.757
2013 Beard DA, Feigl EO. Rebuttal from Daniel Beard and Eric Feigl. The Journal of Physiology. 591: 5801. PMID 24293528 DOI: 10.1113/Jphysiol.2013.264663  0.584
2013 Beard DA, Feigl EO. CrossTalk opposing view: Guyton's venous return curves should not be taught. The Journal of Physiology. 591: 5795-7. PMID 24293526 DOI: 10.1113/Jphysiol.2013.260034  0.536
2013 Bazil JN, Vinnakota KC, Wu F, Beard DA. Analysis of the kinetics and bistability of ubiquinol:cytochrome c oxidoreductase. Biophysical Journal. 105: 343-55. PMID 23870256 DOI: 10.1016/J.Bpj.2013.05.033  0.335
2013 Beard DA, Feigl EO. Reply to "letter to the editor: a return to the venous return controversy: a visual aid for combatants'". American Journal of Physiology. Heart and Circulatory Physiology. 304: H489. PMID 23377151 DOI: 10.1152/Ajpheart.00886.2012  0.625
2013 Li X, Wu F, Beard DA. Identification of the kinetic mechanism of succinyl-CoA synthetase. Bioscience Reports. 33: 145-63. PMID 23088689 DOI: 10.1042/Bsr20120069  0.338
2013 Sanders MD, Tewari S, Kurth T, Ryan RP, Cowley AW, Beard DA, Carlson BE. Measurement of cardiac function using dual catheterization in the Dahl SS rat on low salt The Faseb Journal. 27. DOI: 10.6084/M9.Figshare.723381.V1  0.641
2013 Bazil J, Vinnakota KC, Fan W, Beard DA. A Minimal Model of Ubiquinol:Cytochrome C Reductase Capable of Simulating Superoxide Production Biophysical Journal. 104: 304a. DOI: 10.1016/J.Bpj.2012.11.1693  0.336
2012 Bugenhagen SM, Beard DA. Specification, construction, and exact reduction of state transition system models of biochemical processes. The Journal of Chemical Physics. 137: 154108. PMID 23083149 DOI: 10.1063/1.4758074  0.77
2012 Tewari SG, Dash RK, Beard DA, Bazil JN. A biophysical model of the mitochondrial ATP-Mg/P(i) carrier. Biophysical Journal. 103: 1616-25. PMID 23062354 DOI: 10.1016/J.Bpj.2012.08.050  0.667
2012 Bassingthwaighte JB, Beard DA, Carlson BE, Dash RK, Vinnakota K. Modeling to link regional myocardial work, metabolism and blood flows. Annals of Biomedical Engineering. 40: 2379-98. PMID 22915334 DOI: 10.1007/S10439-012-0613-5  0.578
2012 Beard DA, Neal ML, Tabesh-Saleki N, Thompson CT, Bassingthwaighte JB, Shimoyama M, Carlson BE. Multiscale modeling and data integration in the virtual physiological rat project. Annals of Biomedical Engineering. 40: 2365-78. PMID 22805979 DOI: 10.1007/S10439-012-0611-7  0.566
2012 Thompson MD, Beard DA, Wu F. Use of partition coefficients in flow-limited physiologically-based pharmacokinetic modeling. Journal of Pharmacokinetics and Pharmacodynamics. 39: 313-27. PMID 22639356 DOI: 10.1007/S10928-012-9252-6  0.343
2012 Beard DA, Mescam M. Mechanisms of pressure-diuresis and pressure-natriuresis in Dahl salt-resistant and Dahl salt-sensitive rats. Bmc Physiology. 12: 6. PMID 22583378 DOI: 10.1186/1472-6793-12-6  0.343
2012 Bugenhagen SM, Beard DA. Specification, Construction, and Exact Reduction of Finite State Transition System Models of Biochemical Processes Biophysical Journal. 102: 5-6. DOI: 10.1016/J.Bpj.2011.11.3245  0.761
2012 Vinnakota KC, Wu F, Beard DA. A Quantitative Description of Oxidative Phosphorylation in Cardiac Mitochondria Biophysical Journal. 102: 572a. DOI: 10.1016/J.Bpj.2011.11.3114  0.34
2012 Beard DA, Neal ML, Tabesh-Saleki N, Thompson CT, Bassingthwaighte JB, Shimoyama M, Carlson BE. Erratum to: Multiscale Modeling and Data Integration in the Virtual Physiological Rat Project Annals of Biomedical Engineering. 40: 2501-2501. DOI: 10.1007/S10439-012-0641-1  0.467
2011 Pradhan RK, Qi F, Beard DA, Dash RK. Characterization of Mg2+ inhibition of mitochondrial Ca2+ uptake by a mechanistic model of mitochondrial Ca2+ uniporter. Biophysical Journal. 101: 2071-81. PMID 22067144 DOI: 10.1016/J.Bpj.2011.09.029  0.306
2011 Qi F, Pradhan RK, Dash RK, Beard DA. Detailed kinetics and regulation of mammalian 2-oxoglutarate dehydrogenase. Bmc Biochemistry. 12: 53. PMID 21943256 DOI: 10.1186/1471-2091-12-53  0.35
2011 Wu F, Beard DA, Frisbee JC. Computational analyses of intravascular tracer washout reveal altered capillary-level flow distributions in obese Zucker rats. The Journal of Physiology. 589: 4527-43. PMID 21788350 DOI: 10.1113/Jphysiol.2011.209775  0.311
2011 Vinnakota KC, Dash RK, Beard DA. Stimulatory effects of calcium on respiration and NAD(P)H synthesis in intact rat heart mitochondria utilizing physiological substrates cannot explain respiratory control in vivo. The Journal of Biological Chemistry. 286: 30816-22. PMID 21757763 DOI: 10.1074/Jbc.M111.242529  0.314
2011 Beard DA, Feigl EO. Understanding Guyton's venous return curves. American Journal of Physiology. Heart and Circulatory Physiology. 301: H629-33. PMID 21666119 DOI: 10.1152/Ajpheart.00228.2011  0.616
2011 Thompson MD, Beard DA. Development of appropriate equations for physiologically based pharmacokinetic modeling of permeability-limited and flow-limited transport. Journal of Pharmacokinetics and Pharmacodynamics. 38: 405-21. PMID 21584718 DOI: 10.1007/S10928-011-9200-X  0.35
2011 Carlson BE, Beard DA. Mechanical control of cation channels in the myogenic response. American Journal of Physiology. Heart and Circulatory Physiology. 301: H331-43. PMID 21572020 DOI: 10.1152/Ajpheart.00131.2011  0.323
2011 Waltemath D, Adams R, Beard DA, Bergmann FT, Bhalla US, Britten R, Chelliah V, Cooling MT, Cooper J, Crampin EJ, Garny A, Hoops S, Hucka M, Hunter P, Klipp E, et al. Minimum Information About a Simulation Experiment (MIASE). Plos Computational Biology. 7: e1001122. PMID 21552546 DOI: 10.1371/Journal.Pcbi.1001122  0.302
2011 Mescam M, Vinnakota KC, Beard DA. Identification of the catalytic mechanism and estimation of kinetic parameters for fumarase. The Journal of Biological Chemistry. 286: 21100-9. PMID 21498518 DOI: 10.1074/Jbc.M110.214452  0.341
2011 Vinnakota KC, Beard DA. Kinetic analysis and design of experiments to identify the catalytic mechanism of the monocarboxylate transporter isoforms 4 and 1. Biophysical Journal. 100: 369-80. PMID 21244833 DOI: 10.1016/J.Bpj.2010.11.079  0.324
2011 Beard DA. Simulation of cellular biochemical system kinetics. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 136-46. PMID 21171044 DOI: 10.1002/Wsbm.116  0.333
2011 Waters SL, Alastruey J, Beard DA, Bovendeerd PH, Davies PF, Jayaraman G, Jensen OE, Lee J, Parker KH, Popel AS, Secomb TW, Siebes M, Sherwin SJ, Shipley RJ, Smith NP, et al. Theoretical models for coronary vascular biomechanics: progress & challenges. Progress in Biophysics and Molecular Biology. 104: 49-76. PMID 21040741 DOI: 10.1016/J.Pbiomolbio.2010.10.001  0.365
2011 Fink M, Niederer SA, Cherry EM, Fenton FH, Koivumäki JT, Seemann G, Thul R, Zhang H, Sachse FB, Beard D, Crampin EJ, Smith NP. Cardiac cell modelling: observations from the heart of the cardiac physiome project. Progress in Biophysics and Molecular Biology. 104: 2-21. PMID 20303361 DOI: 10.1016/J.Pbiomolbio.2010.03.002  0.381
2010 Chen X, Qi F, Dash RK, Beard DA. Kinetics and regulation of mammalian NADH-ubiquinone oxidoreductase (Complex I). Biophysical Journal. 99: 1426-36. PMID 20816054 DOI: 10.1016/J.Bpj.2010.06.063  0.341
2010 Li X, Dash RK, Pradhan RK, Qi F, Thompson M, Vinnakota KC, Wu F, Yang F, Beard DA. A database of thermodynamic quantities for the reactions of glycolysis and the tricarboxylic acid cycle. The Journal of Physical Chemistry. B. 114: 16068-82. PMID 20446702 DOI: 10.1021/Jp911381P  0.334
2010 Bugenhagen SM, Cowley AW, Beard DA. Identifying physiological origins of baroreflex dysfunction in salt-sensitive hypertension in the Dahl SS rat. Physiological Genomics. 42: 23-41. PMID 20354102 DOI: 10.1152/Physiolgenomics.00027.2010  0.765
2010 Pradhan RK, Beard DA, Dash RK. A biophysically based mathematical model for the kinetics of mitochondrial Na+-Ca2+ antiporter. Biophysical Journal. 98: 218-30. PMID 20338843 DOI: 10.1016/J.Bpj.2009.10.005  0.308
2009 Xie D, Dash RK, Beard DA. An Improved Algorithm and Its Parallel Implementation for Solving a General Blood-Tissue Transport and Metabolism Model. Journal of Computational Physics. 228: 7850-7861. PMID 20161089 DOI: 10.1016/J.Jcp.2009.07.024  0.307
2009 Beard DA, Kushmerick MJ. Strong inference for systems biology. Plos Computational Biology. 5: e1000459. PMID 19714210 DOI: 10.1371/Journal.Pcbi.1000459  0.323
2009 Beard DA, Britten R, Cooling MT, Garny A, Halstead MD, Hunter PJ, Lawson J, Lloyd CM, Marsh J, Miller A, Nickerson DP, Nielsen PM, Nomura T, Subramanium S, Wimalaratne SM, et al. CellML metadata standards, associated tools and repositories. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 367: 1845-67. PMID 19380315 DOI: 10.1098/Rsta.2008.0310  0.359
2009 Wu F, Zhang J, Beard DA. Experimentally observed phenomena on cardiac energetics in heart failure emerge from simulations of cardiac metabolism. Proceedings of the National Academy of Sciences of the United States of America. 106: 7143-8. PMID 19357309 DOI: 10.1073/Pnas.0812768106  0.354
2009 Wu F, Beard DA. Roles of the creatine kinase system and myoglobin in maintaining energetic state in the working heart. Bmc Systems Biology. 3: 22. PMID 19228404 DOI: 10.1186/1752-0509-3-22  0.366
2008 Secomb TW, Beard DA, Frisbee JC, Smith NP, Pries AR. The role of theoretical modeling in microcirculation research. Microcirculation (New York, N.Y. : 1994). 15: 693-8. PMID 18946803 DOI: 10.1080/10739680802349734  0.342
2008 Dash RK, Li Y, Kim J, Beard DA, Saidel GM, Cabrera ME. Metabolic dynamics in skeletal muscle during acute reduction in blood flow and oxygen supply to mitochondria: in-silico studies using a multi-scale, top-down integrated model. Plos One. 3: e3168. PMID 18779864 DOI: 10.1371/Journal.Pone.0003168  0.38
2008 Qi F, Chen X, Beard DA. Detailed kinetics and regulation of mammalian NAD-linked isocitrate dehydrogenase. Biochimica Et Biophysica Acta. 1784: 1641-51. PMID 18672100 DOI: 10.1016/J.Bbapap.2008.07.001  0.334
2008 Beard DA. Comment on 'Dynamic analysis of optimality in myocardial energy metabolism under normal and ischemic conditions'. Molecular Systems Biology. 4: 207; discussion 208. PMID 18628747 DOI: 10.1038/Msb.2008.37  0.302
2008 Wu F, Zhang EY, Zhang J, Bache RJ, Beard DA. Phosphate metabolite concentrations and ATP hydrolysis potential in normal and ischaemic hearts. The Journal of Physiology. 586: 4193-208. PMID 18617566 DOI: 10.1113/Jphysiol.2008.154732  0.385
2008 Beard DA, Wu F, Cabrera ME, Dash RK. Modeling of cellular metabolism and microcirculatory transport. Microcirculation (New York, N.Y. : 1994). 15: 777-93. PMID 18608987 DOI: 10.1080/10739680802019709  0.316
2008 Dash RK, Beard DA. Analysis of cardiac mitochondrial Na+-Ca2+ exchanger kinetics with a biophysical model of mitochondrial Ca2+ handling suggests a 3:1 stoichiometry. The Journal of Physiology. 586: 3267-85. PMID 18467367 DOI: 10.1113/Jphysiol.2008.151977  0.317
2007 Wu F, Yang F, Vinnakota KC, Beard DA. Computer modeling of mitochondrial tricarboxylic acid cycle, oxidative phosphorylation, metabolite transport, and electrophysiology. The Journal of Biological Chemistry. 282: 24525-37. PMID 17591785 DOI: 10.1074/Jbc.M701024200  0.396
2007 Smith NP, Crampin EJ, Niederer SA, Bassingthwaighte JB, Beard DA. Computational biology of cardiac myocytes: proposed standards for the physiome. The Journal of Experimental Biology. 210: 1576-83. PMID 17449822 DOI: 10.1242/Jeb.000133  0.546
2007 Beard DA, Qian H. Relationship between thermodynamic driving force and one-way fluxes in reversible processes. Plos One. 2: e144. PMID 17206279 DOI: 10.1371/Journal.Pone.0000144  0.301
2007 Wu F, Jeneson JA, Beard DA. Oxidative ATP synthesis in skeletal muscle is controlled by substrate feedback. American Journal of Physiology. Cell Physiology. 292: C115-24. PMID 16837647 DOI: 10.1152/Ajpcell.00237.2006  0.335
2006 Qian H, Beard DA. Metabolic futile cycles and their functions: a systems analysis of energy and control. Systems Biology. 153: 192-200. PMID 16986621 DOI: 10.1049/Ip-Syb:20050086  0.309
2006 Beard DA. Modeling of oxygen transport and cellular energetics explains observations on in vivo cardiac energy metabolism. Plos Computational Biology. 2: e107. PMID 16978045 DOI: 10.1371/Journal.Pcbi.0020107  0.398
2005 Beard DA, Bassingthwaighte JB, Greene AS. Computational modeling of physiological systems. Physiological Genomics. 23: 1-3; discussion 4. PMID 16179418 DOI: 10.1152/Physiolgenomics.00117.2005  0.499
2005 Beard DA. A biophysical model of the mitochondrial respiratory system and oxidative phosphorylation. Plos Computational Biology. 1: e36. PMID 16163394 DOI: 10.1371/Journal.Pcbi.0010036  0.388
2005 Qian H, Beard DA. Thermodynamics of stoichiometric biochemical networks in living systems far from equilibrium. Biophysical Chemistry. 114: 213-20. PMID 15829355 DOI: 10.1016/J.Bpc.2004.12.001  0.307
2005 Ejike JC, Arakaki LS, Beard DA, Ciesielski WA, Feigl EO, Schenkman KA. Myocardial oxygenation and adenosine release in isolated guinea pig hearts during changes in contractility. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2062-7. PMID 15591100 DOI: 10.1152/Ajpheart.00777.2004  0.603
2005 Beard DA, Qian H. Thermodynamic-based computational profiling of cellular regulatory control in hepatocyte metabolism. American Journal of Physiology. Endocrinology and Metabolism. 288: E633-44. PMID 15507536 DOI: 10.1152/Ajpendo.00239.2004  0.313
2005 Beard DA. Integrated Computational Modeling of Oxygen Transport and Cellular Energetics Explains Observations on In Vivo Cardiac Oxygen Consumption and Energy Metabolites Plos Computational Biology. DOI: 10.1371/Journal.Pcbi.0020107.Eor  0.317
2003 Beard DA, Schenkman KA, Feigl EO. Myocardial oxygenation in isolated hearts predicted by an anatomically realistic microvascular transport model. American Journal of Physiology. Heart and Circulatory Physiology. 285: H1826-36. PMID 12869375 DOI: 10.1152/Ajpheart.00380.2003  0.606
2003 Schenkman KA, Beard DA, Ciesielski WA, Feigl EO. Comparison of buffer and red blood cell perfusion of guinea pig heart oxygenation. American Journal of Physiology. Heart and Circulatory Physiology. 285: H1819-25. PMID 12869374 DOI: 10.1152/Ajpheart.00383.2003  0.598
2001 Bassingthwaighte JB, Beard DA, Li Z. The mechanical and metabolic basis of myocardial blood flow heterogeneity. Basic Research in Cardiology. 96: 582-94. PMID 11770077 DOI: 10.1007/S003950170010  0.524
2001 Beard DA. Computational framework for generating transport models from databases of microvascular anatomy. Annals of Biomedical Engineering. 29: 837-43. PMID 11764314 DOI: 10.1114/1.1408920  0.306
2001 Beard DA, Bassingthwaighte JB. Modeling advection and diffusion of oxygen in complex vascular networks. Annals of Biomedical Engineering. 29: 298-310. PMID 11339327 DOI: 10.1114/1.1359450  0.531
2000 Beard DA, Bassingthwaighte JB. The fractal nature of myocardial blood flow emerges from a whole-organ model of arterial network. Journal of Vascular Research. 37: 282-96. PMID 10965227 DOI: 10.1159/000025742  0.537
2000 Beard DA, Bassingthwaighte JB. Advection and diffusion of substances in biological tissues with complex vascular networks. Annals of Biomedical Engineering. 28: 253-68. PMID 10784090 DOI: 10.1114/1.273  0.555
2000 Karch R, Neumann F, Neumann M, Schreiner W, Dawes M, Ritter JM, Axel DI, Spyridopoulos I, Riessen R, Runge H, Viebahn R, Karsch KR, Keravis T, Komas N, Lugnier C, ... ... Beard DA, et al. Author Index (Abstracts only) Journal of Vascular Research. 37: 340-341. DOI: 10.1159/000025746  0.443
2000 Karch R, Neumann F, Neumann M, Schreiner W, Dawes M, Ritter JM, Axel DI, Spyridopoulos I, Riessen R, Runge H, Viebahn R, Karsch KR, Keravis T, Komas N, Lugnier C, ... ... Beard DA, et al. Annual Meeting of the Deutsche Gesellschaft für Mikrozirkulation und Vaskuläre Biologie e.V. Journal of Vascular Research. 37: 305-339. DOI: 10.1159/000025745  0.451
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