Robert S. Langer - Publications

Affiliations: 
Biological Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Drug Delivery, Biotechnology, Immobilized Enzymes, Biomedical Engineering
Website:
http://web.mit.edu/langerlab/langer.html

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lim DK, Barhoumi A, Wylie RG, Reznor G, Langer RS, Kohane DS. Correction to "Enhanced Photothermal Effect of Plasmonic Nanoparticles Coated with Reduced Graphene Oxide". Nano Letters. PMID 38236080 DOI: 10.1021/acs.nanolett.3c05125  0.596
2024 Bochenek MA, Walters B, Zhang J, Fenton OS, Facklam A, Kroneková Z, Pelach M, Engquist EN, Leite NC, Morgart A, Lacík I, Langer R, Anderson DG. Enhancing the Functionality of Immunoisolated Human SC-βeta Cell Clusters through Prior Resizing. Small (Weinheim An Der Bergstrasse, Germany). e2307464. PMID 38212275 DOI: 10.1002/smll.202307464  0.458
2023 Jiang AY, Witten J, Raji IO, Eweje F, MacIsaac C, Meng S, Oladimeji FA, Hu Y, Manan RS, Langer R, Anderson DG. Combinatorial development of nebulized mRNA delivery formulations for the lungs. Nature Nanotechnology. PMID 37985700 DOI: 10.1038/s41565-023-01548-3  0.494
2023 Wang EY, Sarmadi M, Ying B, Jaklenec A, Langer R. Recent advances in nano- and micro-scale carrier systems for controlled delivery of vaccines. Biomaterials. 303: 122345. PMID 37918182 DOI: 10.1016/j.biomaterials.2023.122345  0.779
2023 Gao J, Karp JM, Langer R, Joshi N. The Future of Drug Delivery. Chemistry of Materials : a Publication of the American Chemical Society. 35: 359-363. PMID 37799624 DOI: 10.1021/acs.chemmater.2c03003  0.485
2023 Krishnan SR, Liu C, Bochenek MA, Bose S, Khatib N, Walters B, O'Keeffe L, Facklam A, Langer R, Anderson DG. A wireless, battery-free device enables oxygen generation and immune protection of therapeutic xenotransplants in vivo. Proceedings of the National Academy of Sciences of the United States of America. 120: e2311707120. PMID 37738292 DOI: 10.1073/pnas.2311707120  0.704
2023 Navamajiti N, Gardner A, Cao R, Sugimoto Y, Yang JW, Lopes A, Phan NV, Collins J, Hua T, Damrongsakkul S, Kanokpanont S, Steiger C, Reker D, Langer R, Traverso G. Silk Fibroin-Based Coatings for Pancreatin-Dependent Drug Delivery. Journal of Pharmaceutical Sciences. PMID 37690778 DOI: 10.1016/j.xphs.2023.09.001  0.65
2023 Li B, Jiang AY, Raji I, Atyeo C, Raimondo TM, Gordon AGR, Rhym LH, Samad T, MacIsaac C, Witten J, Mughal H, Chicz TM, Xu Y, McNamara RP, Bhatia S, ... ... Langer R, et al. Enhancing the immunogenicity of lipid-nanoparticle mRNA vaccines by adjuvanting the ionizable lipid and the mRNA. Nature Biomedical Engineering. PMID 37679571 DOI: 10.1038/s41551-023-01082-6  0.582
2023 Kim H, Kirtane AR, Kim NY, Rajesh NU, Tang C, Ishida K, Hayward AM, Langer R, Traverso G. Gastrointestinal Delivery of an mRNA Vaccine Using Immunostimulatory Polymeric Nanoparticles. The Aaps Journal. 25: 81. PMID 37589795 DOI: 10.1208/s12248-023-00844-z  0.659
2023 Sun S, Wang M, Knupp SA, Soto-Feliciano Y, Hu X, Kaplan DL, Langer R, Anderson DG, Xu Q. Correction to "Combinatorial Library of Lipidoids for In Vitro DNA Delivery". Bioconjugate Chemistry. PMID 37378616 DOI: 10.1021/acs.bioconjchem.3c00268  0.456
2023 Doloff JC, Ma M, Sadraei A, Tam HH, Farah S, Hollister-Lock J, Vegas AJ, Veiseh O, Quiroz VM, Rakoski A, Aresta-DaSilva S, Bader AR, Griffin M, Weir GC, Brehm MA, ... ... Langer R, et al. Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response. Science Advances. 9: eade9488. PMID 37327334 DOI: 10.1126/sciadv.ade9488  0.789
2023 Guimarães PPG, Figueroa-Espada CG, Riley RS, Gong N, Xue L, Sewastianik T, Dennis PS, Loebel C, Chung A, Shepherd SJ, Haley RM, Hamilton AG, El-Mayta R, Wang K, Langer R, et al. In vivo bone marrow microenvironment siRNA delivery using lipid-polymer nanoparticles for multiple myeloma therapy. Proceedings of the National Academy of Sciences of the United States of America. 120: e2215711120. PMID 37310997 DOI: 10.1073/pnas.2215711120  0.791
2023 Herrera-Mora G, Solis-Chaves P, Hernandez-Aviles G, Graham EM, Clausen-Oreamuno C, Castro-Cespedes JA, Haupt J, Jamiel M, Veiseh O, Sforza M, Hancock J, Kinney B, De Mezerville R, Langer R, Doloff JC, et al. Ultrasonographic Identification of Shell Surface Types in Commercially Available Silicone Gel-Filled Breast Implants. Plastic and Reconstructive Surgery. PMID 37224221 DOI: 10.1097/PRS.0000000000010758  0.615
2023 Bhagchandani SH, Vohidov F, Milling LE, Tong EY, Brown CM, Ramseier ML, Liu B, Fessenden TB, Nguyen HV, Kiel GR, Won L, Langer RS, Spranger S, Shalek AK, Irvine DJ, et al. Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation. Science Advances. 9: eadg2239. PMID 37075115 DOI: 10.1126/sciadv.adg2239  0.445
2023 Raimondo TM, Reed K, Shi D, Langer R, Anderson DG. Delivering the next generation of cancer immunotherapies with RNA. Cell. 186: 1535-1540. PMID 37059063 DOI: 10.1016/j.cell.2023.02.031  0.456
2023 Li B, Manan RS, Liang SQ, Gordon A, Jiang A, Varley A, Gao G, Langer R, Xue W, Anderson D. Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing. Nature Biotechnology. PMID 36997680 DOI: 10.1038/s41587-023-01679-x  0.479
2022 Volpatti LR, Bochenek MA, Facklam AL, Burns DM, MacIsaac C, Morgart A, Walters B, Langer R, Anderson DG. Partially Oxidized Alginate as a Biodegradable Carrier for Glucose-Responsive Insulin Delivery and Islet Cell Replacement Therapy. Advanced Healthcare Materials. e2201822. PMID 36325648 DOI: 10.1002/adhm.202201822  0.501
2022 Sarmadi M, Ta C, VanLonkhuyzen AM, De Fiesta DC, Kanelli M, Sadeghi I, Behrens AM, Ingalls B, Menon N, Daristotle JL, Yu J, Langer R, Jaklenec A. Experimental and computational understanding of pulsatile release mechanism from biodegradable core-shell microparticles. Science Advances. 8: eabn5315. PMID 35857507 DOI: 10.1126/sciadv.abn5315  0.741
2022 Sadeghi I, Lu X, Sarmadi M, Langer R, Jaklenec A. Micromolding of Thermoplastic Polymers for Direct Fabrication of Discrete, Multilayered Microparticles. Small Methods. e2200232. PMID 35764872 DOI: 10.1002/smtd.202200232  0.75
2022 Kirtane AR, Karavasili C, Wahane A, Freitas D, Booz K, Le DTH, Hua T, Scala S, Lopes A, Hess K, Collins J, Tamang S, Ishida K, Kuosmanen JLP, Rajesh NU, ... ... Langer R, et al. Development of oil-based gels as versatile drug delivery systems for pediatric applications. Science Advances. 8: eabm8478. PMID 35622910 DOI: 10.1126/sciadv.abm8478  0.664
2022 Mead BE, Hattori K, Levy L, Imada S, Goto N, Vukovic M, Sze D, Kummerlowe C, Matute JD, Duan J, Langer R, Blumberg RS, Ordovas-Montanes J, Yilmaz ÖH, Karp JM, et al. Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation. Nature Biomedical Engineering. PMID 35314801 DOI: 10.1038/s41551-022-00863-9  0.474
2022 Labouta HI, Langer R, Cullis PR, Merkel OM, Prausnitz MR, Gomaa Y, Nogueira SS, Kumeria T. Role of drug delivery technologies in the success of COVID-19 vaccines: a perspective. Drug Delivery and Translational Research. PMID 35290656 DOI: 10.1007/s13346-022-01146-1  0.426
2022 Ferdosi S, Tangeysh B, Brown TR, Everley PA, Figa M, McLean M, Elgierari EM, Zhao X, Garcia VJ, Wang T, Chang MEK, Riedesel K, Chu J, Mahoney M, Xia H, ... ... Langer R, et al. Engineered nanoparticles enable deep proteomics studies at scale by leveraging tunable nano-bio interactions. Proceedings of the National Academy of Sciences of the United States of America. 119: e2106053119. PMID 35275789 DOI: 10.1073/pnas.2106053119  0.47
2022 Booty MG, Hlavaty KA, Stockmann A, Ozay EI, Smith C, Tian L, How E, Subramanya D, Venkitaraman A, Yee C, Pryor O, Volk K, Blagovic K, Vicente-Suarez I, Yarar D, ... ... Langer R, et al. Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8 T Cell Responses with Antitumor Activity. Journal of Immunology (Baltimore, Md. : 1950). PMID 35091434 DOI: 10.4049/jimmunol.2100656  0.604
2021 Makvandi P, Jamaledin R, Chen G, Baghbantaraghdari Z, Zare EN, Di Natale C, Onesto V, Vecchione R, Lee J, Tay FR, Netti P, Mattoli V, Jaklenec A, Gu Z, Langer R. Stimuli-responsive transdermal microneedle patches. Materials Today (Kidlington, England). 47: 206-222. PMID 36338772 DOI: 10.1016/j.mattod.2021.03.012  0.373
2021 Lee SH, Wan Q, Wentworth A, Ballinger I, Ishida K, Collins JE, Tamang S, Huang HW, Li C, Hess K, Lopes A, Kirtane AR, Lee JS, Lee S, Chen W, ... ... Langer R, et al. Implantable system for chronotherapy. Science Advances. 7: eabj4624. PMID 34826238 DOI: 10.1126/sciadv.abj4624  0.643
2021 Yang K, O'Cearbhaill ED, Liu SS, Zhou A, Chitnis GD, Hamilos AE, Xu J, Verma MKS, Giraldo JA, Kudo Y, Lee EA, Lee Y, Pop R, Langer R, Melton DA, et al. A therapeutic convection-enhanced macroencapsulation device for enhancing β cell viability and insulin secretion. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34504013 DOI: 10.1073/pnas.2101258118  0.703
2021 Volpatti LR, Burns DM, Basu A, Langer R, Anderson DG. Engineered insulin-polycation complexes for glucose-responsive delivery with high insulin loading. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 34391834 DOI: 10.1016/j.jconrel.2021.08.017  0.456
2021 Doloff JC, Veiseh O, de Mezerville R, Sforza M, Perry TA, Haupt J, Jamiel M, Chambers C, Nash A, Aghlara-Fotovat S, Stelzel JL, Bauer SJ, Neshat SY, Hancock J, Romero NA, ... ... Langer R, et al. The surface topography of silicone breast implants mediates the foreign body response in mice, rabbits and humans. Nature Biomedical Engineering. PMID 34155355 DOI: 10.1038/s41551-021-00739-4  0.629
2021 Dolo JC, Veiseh O, Vegas AJ, Tam HH, Farah S, Ma M, Li J, Bader A, Chiu A, Sadraei A, Aresta-Dasilva S, Grin M, Jhunjhunwala S, Webber M, Siebert S, ... ... Langer R, et al. Author Correction: Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates. Nature Materials. PMID 34012046 DOI: 10.1038/s41563-021-01023-1  0.768
2021 Reker D, Rybakova Y, Kirtane AR, Cao R, Yang JW, Navamajiti N, Gardner A, Zhang RM, Esfandiary T, L'Heureux J, von Erlach T, Smekalova EM, Leboeuf D, Hess K, Lopes A, ... ... Langer R, et al. Computationally guided high-throughput design of self-assembling drug nanoparticles. Nature Nanotechnology. PMID 33767382 DOI: 10.1038/s41565-021-00870-y  0.676
2021 Kirtane AR, Verma M, Karandikar P, Furin J, Langer R, Traverso G. Nanotechnology approaches for global infectious diseases. Nature Nanotechnology. 16: 369-384. PMID 33753915 DOI: 10.1038/s41565-021-00866-8  0.647
2021 McLean WJ, Hinton AS, Herby JTJ, Salt AN, Hartsock JJ, Wilson S, Lucchino DL, Lenarz T, Warnecke A, Prenzler N, Schmitt H, King S, Jackson LE, Rosenbloom J, Atiee G, ... ... Langer R, et al. Improved Speech Intelligibility in Subjects With Stable Sensorineural Hearing Loss Following Intratympanic Dosing of FX-322 in a Phase 1b Study. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. PMID 33617194 DOI: 10.1097/MAO.0000000000003120  0.453
2021 Li W, Qiu J, Li XL, Aday S, Zhang J, Conley G, Xu J, Joseph J, Lan H, Langer R, Mannix R, Karp JM, Joshi N. BBB pathophysiology-independent delivery of siRNA in traumatic brain injury. Science Advances. 7. PMID 33523853 DOI: 10.1126/sciadv.abd6889  0.477
2021 Sadeghi I, Byrne J, Shakur R, Langer R. Engineered drug delivery devices to address Global Health challenges. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 33516755 DOI: 10.1016/j.jconrel.2021.01.035  0.739
2020 Mitchell MJ, Billingsley MM, Haley RM, Wechsler ME, Peppas NA, Langer R. Engineering precision nanoparticles for drug delivery. Nature Reviews. Drug Discovery. PMID 33277608 DOI: 10.1038/s41573-020-0090-8  0.796
2020 Volpatti LR, Facklam AL, Cortinas AB, Lu YC, Matranga MA, MacIsaac C, Hill MC, Langer R, Anderson DG. Microgel encapsulated nanoparticles for glucose-responsive insulin delivery. Biomaterials. 267: 120458. PMID 33197650 DOI: 10.1016/j.biomaterials.2020.120458  0.465
2020 Corbo C, Li AA, Poustchi H, Lee GY, Stacks S, Molinaro R, Ma P, Platt T, Behzadi S, Langer R, Farias V, Farokhzad OC. Analysis of the Human Plasma Proteome Using Multi-Nanoparticle Protein Corona for Detection of Alzheimer's Disease. Advanced Healthcare Materials. e2000948. PMID 33169521 DOI: 10.1002/adhm.202000948  0.446
2020 Chu CK, Joseph AJ, Limjoco MD, Yang J, Bose S, Thapa LS, Langer R, Anderson DG. Chemical Tuning of Fibers Drawn from Extensible Hyaluronic Acid Networks. Journal of the American Chemical Society. PMID 33141568 DOI: 10.1021/jacs.0c09691  0.737
2020 Tang Z, Kong N, Zhang X, Liu Y, Hu P, Mou S, Liljeström P, Shi J, Tan W, Kim JS, Cao Y, Langer R, Leong KW, Farokhzad OC, Tao W. A materials-science perspective on tackling COVID-19. Nature Reviews. Materials. 1-14. PMID 33078077 DOI: 10.1038/s41578-020-00247-y  0.583
2020 Krohn-Grimberghe M, Mitchell MJ, Schloss MJ, Khan OF, Courties G, Guimaraes PPG, Rohde D, Cremer S, Kowalski PS, Sun Y, Tan M, Webster J, Wang K, Iwamoto Y, Schmidt SP, ... ... Langer R, et al. Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche. Nature Biomedical Engineering. PMID 33020600 DOI: 10.1038/s41551-020-00623-7  0.632
2020 Abramson A, Dellal D, Kong YL, Zhou J, Gao Y, Collins J, Tamang S, Wainer J, McManus R, Hayward A, Frederiksen MR, Water JJ, Jensen B, Roxhed N, Langer R, et al. Ingestible transiently anchoring electronics for microstimulation and conductive signaling. Science Advances. 6: eaaz0127. PMID 32923616 DOI: 10.1126/Sciadv.Aaz0127  0.713
2020 Lu X, Miao L, Gao W, Chen Z, McHugh KJ, Sun Y, Tochka Z, Tomasic S, Sadtler K, Hyacinthe A, Huang Y, Graf T, Hu Q, Sarmadi M, Langer R, et al. Engineered PLGA microparticles for long-term, pulsatile release of STING agonist for cancer immunotherapy. Science Translational Medicine. 12. PMID 32801144 DOI: 10.1126/Scitranslmed.Aaz6606  0.538
2020 McAvoy M, Doloff JC, Khan OF, Rosen J, Langer R, Anderson DG. Vascularized Muscle Flap to Reduce Wound Breakdown During Flexible Electrode-Mediated Functional Electrical Stimulation After Peripheral Nerve Injury. Frontiers in Neurology. 11: 644. PMID 32793094 DOI: 10.3389/Fneur.2020.00644  0.724
2020 Roberts TC, Langer R, Wood MJA. Advances in oligonucleotide drug delivery. Nature Reviews. Drug Discovery. PMID 32782413 DOI: 10.1038/S41573-020-0075-7  0.327
2020 Blume JE, Manning WC, Troiano G, Hornburg D, Figa M, Hesterberg L, Platt TL, Zhao X, Cuaresma RA, Everley PA, Ko M, Liou H, Mahoney M, Ferdosi S, Elgierari EM, ... ... Langer R, et al. Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona. Nature Communications. 11: 3662. PMID 32699280 DOI: 10.1038/S41467-020-17033-7  0.643
2020 Wei T, Cheng Q, Farbiak L, Anderson DG, Langer R, Siegwart DJ. Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for CRISPR/Cas-Based Genome Editing. Acs Nano. PMID 32697075 DOI: 10.1021/Acsnano.0C04707  0.562
2020 Sadtler K, Collins J, Byrne JD, Langer R. Parallel evolution of polymer chemistry and immunology: Integrating mechanistic biology with materials design. Advanced Drug Delivery Reviews. PMID 32589903 DOI: 10.1016/J.Addr.2020.06.021  0.376
2020 Mirvakili SM, Ngo QP, Langer R. Polymer Nanocomposite Microactuators for On-Demand Chemical Release via High-Frequency Magnetic Field Excitation. Nano Letters. PMID 32479730 DOI: 10.1021/Acs.Nanolett.0C00648  0.323
2020 Hrkach J, Langer R. From micro to nano: evolution and impact of drug delivery in treating disease. Drug Delivery and Translational Research. 10: 567-570. PMID 32385828 DOI: 10.1007/S13346-020-00769-6  0.353
2020 Saunders NRM, Paolini MS, Fenton OS, Poul L, Devalliere J, Mpambani F, Darmon A, Bergère M, Jibault O, Germain M, Langer R. A Nanoprimer To Improve the Systemic Delivery of siRNA and mRNA. Nano Letters. PMID 32357299 DOI: 10.1021/Acs.Nanolett.0C00752  0.322
2020 Bose S, Volpatti LR, Thiono D, Yesilyurt V, McGladrigan C, Tang Y, Facklam A, Wang A, Jhunjhunwala S, Veiseh O, Hollister-Lock J, Bhattacharya C, Weir GC, Greiner DL, Langer R, et al. A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells. Nature Biomedical Engineering. PMID 32231313 DOI: 10.1038/S41551-020-0538-5  0.789
2020 Rudra A, Li J, Shakur R, Bhagchandani S, Langer R. Addition to "Trends in Therapeutic Conjugates: Bench to Clinic". Bioconjugate Chemistry. PMID 32202413 DOI: 10.1021/Acs.Bioconjchem.0C00136  0.633
2020 Reker D, Shi Y, Kirtane AR, Hess K, Zhong GJ, Crane E, Lin CH, Langer R, Traverso G. Machine Learning Uncovers Food- and Excipient-Drug Interactions. Cell Reports. 30: 3710-3716.e4. PMID 32187543 DOI: 10.1016/J.Celrep.2020.02.094  0.676
2020 Delcassian D, Luzhansky I, Spanoudaki V, Bochenek M, McGladrigan C, Nguyen A, Norcross S, Zhu Y, Shan CS, Hausser R, Shakesheff KM, Langer R, Anderson DG. Magnetic Retrieval of Encapsulated Beta Cell Transplants from Diabetic Mice Using Dual-Function MRI Visible and Retrievable Microcapsules. Advanced Materials (Deerfield Beach, Fla.). e1904502. PMID 32134138 DOI: 10.1002/Adma.201904502  0.776
2020 Haley RM, Gottardi R, Langer R, Mitchell MJ. Cyclodextrins in drug delivery: applications in gene and combination therapy. Drug Delivery and Translational Research. PMID 32077052 DOI: 10.1007/S13346-020-00724-5  0.735
2020 Yu J, Wang J, Zhang Y, Chen G, Mao W, Ye Y, Kahkoska AR, Buse JB, Langer R, Gu Z. Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs. Nature Biomedical Engineering. PMID 32015407 DOI: 10.1038/S41551-019-0508-Y  0.432
2020 Raman R, Hua T, Gwynne D, Collins J, Tamang S, Zhou J, Esfandiary T, Soares V, Pajovic S, Hayward A, Langer R, Traverso G. Light-degradable hydrogels as dynamic triggers for gastrointestinal applications. Science Advances. 6: eaay0065. PMID 32010768 DOI: 10.1126/Sciadv.Aay0065  0.328
2020 Rudra A, Li J, Shakur R, Bhagchandani S, Langer R. Trends in Therapeutic Conjugates: Bench to Clinic. Bioconjugate Chemistry. PMID 31990184 DOI: 10.1021/Acs.Bioconjchem.9B00828  0.658
2019 Kong YL, Zou X, McCandler CA, Kirtane AR, Ning S, Zhou J, Abid A, Jafari M, Rogner J, Minahan D, Collins JE, McDonnell S, Cleveland C, Bensel T, Tamang S, ... ... Langer R, et al. 3D-Printed Gastric Resident Electronics. Advanced Materials Technologies. 4: 1800490. PMID 32010758 DOI: 10.1002/Admt.201800490  0.772
2019 Smekalova EM, Gerashchenko MV, O'Connor PBF, Whittaker CA, Kauffman KJ, Fefilova AS, Zatsepin TS, Bogorad RL, Baranov PV, Langer R, Gladyshev VN, Anderson DG, Koteliansky V. In Vivo RNAi-Mediated eIF3m Knockdown Affects Ribosome Biogenesis and Transcription but Has Limited Impact on mRNA-Specific Translation. Molecular Therapy. Nucleic Acids. 19: 252-266. PMID 31855834 DOI: 10.1016/J.Omtn.2019.11.009  0.52
2019 Kirtane AR, Hua T, Hayward A, Bajpayee A, Wahane A, Lopes A, Bensel T, Ma L, Stanczyk FZ, Brooks S, Gwynne D, Wainer J, Collins J, Tamang SM, Langer R, et al. A once-a-month oral contraceptive. Science Translational Medicine. 11. PMID 31801885 DOI: 10.1126/Scitranslmed.Aay2602  0.768
2019 Volpatti LR, Matranga MA, Cortinas AB, Delcassian D, Daniel KB, Langer R, Anderson DG. Glucose-Responsive Nanoparticles for Rapid and Extended Self-Regulated Insulin Delivery. Acs Nano. PMID 31765558 DOI: 10.1021/Acsnano.9B06395  0.775
2019 Yeom J, Guimaraes PPG, Ahn HM, Jung BK, Hu Q, McHugh K, Mitchell MJ, Yun CO, Langer R, Jaklenec A. Chiral Supraparticles for Controllable Nanomedicine. Advanced Materials (Deerfield Beach, Fla.). e1903878. PMID 31686433 DOI: 10.1002/Adma.201903878  0.508
2019 Fenton OS, Tibbitt MW, Appel EA, Jhunjhunwala S, Webber MJ, Langer R. Injectable Polymer-Nanoparticle Hydrogels for Local Immune Cell Recruitment. Biomacromolecules. PMID 31682423 DOI: 10.1021/Acs.Biomac.9B01129  0.801
2019 McAvoy M, Tsosie JK, Vyas KN, Khan OF, Sadtler K, Langer R, Anderson DG. Flexible Multielectrode Array for Skeletal Muscle Conditioning, Acetylcholine Receptor Stabilization and Epimysial Recording After Critical Peripheral Nerve Injury. Theranostics. 9: 7099-7107. PMID 31660089 DOI: 10.7150/Thno.35436  0.511
2019 Abramson A, Caffarel-Salvador E, Soares V, Minahan D, Tian RY, Lu X, Dellal D, Gao Y, Kim S, Wainer J, Collins J, Tamang S, Hayward A, Yoshitake T, Lee HC, ... ... Langer R, et al. A luminal unfolding microneedle injector for oral delivery of macromolecules. Nature Medicine. PMID 31591601 DOI: 10.1038/S41591-019-0598-9  0.339
2019 Lee MA, Duarte CM, Eguíluz VM, Heller DA, Langer R, Meekan MG, Sikes HD, Srivastava M, Strano MS, Wilson RP. Can Fish and Cell Phones Teach Us about Our Health? Acs Sensors. PMID 31576740 DOI: 10.1021/Acssensors.9B00947  0.614
2019 Miao L, Li L, Huang Y, Delcassian D, Chahal J, Han J, Shi Y, Sadtler K, Gao W, Lin J, Doloff JC, Langer R, Anderson DG. Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation. Nature Biotechnology. PMID 31570898 DOI: 10.1038/S41587-019-0247-3  0.776
2019 Farah S, Doloff JC, Müller P, Sadraei A, Han HJ, Olafson K, Vyas K, Tam HH, Hollister-Lock J, Kowalski PS, Griffin M, Meng A, McAvoy M, Graham AC, McGarrigle J, ... ... Langer R, et al. Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations. Nature Materials. PMID 31235902 DOI: 10.1038/S41563-019-0377-5  0.755
2019 Chauhan VP, Chen IX, Tong R, Ng MR, Martin JD, Naxerova K, Wu MW, Huang P, Boucher Y, Kohane DS, Langer R, Jain RK. Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 31040208 DOI: 10.1073/Pnas.1819889116  0.641
2019 France MM, Del Rio T, Travers H, Raftery E, Xu K, Langer R, Traverso G, Lennerz JK, Schoellhammer CM. Ultra-rapid drug delivery in the oral cavity using ultrasound. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31039376 DOI: 10.1016/J.Jconrel.2019.04.037  0.338
2019 Babaee S, Pajovic S, Kirtane AR, Shi J, Caffarel-Salvador E, Hess K, Collins JE, Tamang S, Wahane AV, Hayward AM, Mazdiyasni H, Langer R, Traverso G. Temperature-responsive biometamaterials for gastrointestinal applications. Science Translational Medicine. 11. PMID 30996082 DOI: 10.1126/Scitranslmed.Aau8581  0.783
2019 Srinivasan S, Vyas K, McAvoy M, Calvaresi P, Khan OF, Langer R, Anderson DG, Herr H. Polyimide Electrode-Based Electrical Stimulation Impedes Early Stage Muscle Graft Regeneration. Frontiers in Neurology. 10: 252. PMID 30967830 DOI: 10.3389/Fneur.2019.00252  0.508
2019 Paolini MS, Fenton OS, Bhattacharya C, Andresen JL, Langer R. Polymers for extended-release administration. Biomedical Microdevices. 21: 45. PMID 30963297 DOI: 10.1007/S10544-019-0386-9  0.718
2019 Spanoudaki V, Doloff JC, Huang W, Norcross SR, Farah S, Langer R, Anderson DG. Simultaneous spatiotemporal tracking and oxygen sensing of transient implants in vivo using hot-spot MRI and machine learning. Proceedings of the National Academy of Sciences of the United States of America. PMID 30808810 DOI: 10.1073/Pnas.1815909116  0.736
2019 Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, ... ... Langer R, et al. BOLA3 Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension. Circulation. PMID 30759996 DOI: 10.1161/Circulationaha.118.035889  0.482
2019 Abramson A, Caffarel-Salvador E, Khang M, Dellal D, Silverstein D, Gao Y, Frederiksen MR, Vegge A, Hubálek F, Water JJ, Friderichsen AV, Fels J, Kirk RK, Cleveland C, Collins J, ... ... Langer R, et al. An ingestible self-orienting system for oral delivery of macromolecules. Science (New York, N.Y.). 363: 611-615. PMID 30733413 DOI: 10.1126/Science.Aau2277  0.318
2019 Hoffman T, Khademhosseini A, Langer RS. Chasing the Paradigm: Clinical Translation of 25 Years of Tissue Engineering. Tissue Engineering. Part A. PMID 30727841 DOI: 10.1089/Ten.Tea.2019.0032  0.551
2019 Riley RS, June CH, Langer R, Mitchell MJ. Delivery technologies for cancer immunotherapy. Nature Reviews. Drug Discovery. PMID 30622344 DOI: 10.1038/S41573-018-0006-Z  0.763
2019 Patel AK, Kaczmarek JC, Bose S, Kauffman KJ, Mir F, Heartlein MW, DeRosa F, Langer R, Anderson DG. Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium. Advanced Materials (Deerfield Beach, Fla.). e1805116. PMID 30609147 DOI: 10.1002/Adma.201805116  0.717
2019 Zelikin A, Shastri VR, Langer R. Facile Synthesis of 3-Alkylpyrroles. The Journal of Organic Chemistry. 64: 3379-3380. PMID 11674451 DOI: 10.1021/Jo9823339  0.52
2019 Santini JT, Richards AC, Scheidt R, Cima MJ, Langer R. Microchips as Controlled Drug-Delivery Devices. Angewandte Chemie (International Ed. in English). 39: 2396-2407. PMID 10941095 DOI: 10.1002/1521-3773(20000717)39:14<2396::Aid-Anie2396>3.0.Co;2-U  0.327
2019 Marler JJ, Upton J, Langer R, Vacanti JP. Transplantation of cells in matrices for tissue regeneration. Advanced Drug Delivery Reviews. 33: 165-182. PMID 10837658 DOI: 10.1016/S0169-409X(98)00025-8  0.525
2019 Patel AK, Kaczmarek JC, Bose S, Kauffman KJ, Mir F, Heartlein MW, DeRosa F, Langer R, Anderson DG. Gene Delivery: Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium (Adv. Mater. 8/2019) Advanced Materials. 31: 1970053. DOI: 10.1002/Adma.201970053  0.698
2018 Kowalski PS, Bhattacharya C, Afewerki S, Langer R. Smart Biomaterials: Recent Advances and Future Directions. Acs Biomaterials Science & Engineering. 4: 3809-3817. PMID 33429614 DOI: 10.1021/acsbiomaterials.8b00889  0.68
2018 Bisso PW, Gaglione S, Guimarães PPG, Mitchell MJ, Langer R. Nanomaterial Interactions with Human Neutrophils. Acs Biomaterials Science & Engineering. 4: 4255-4265. PMID 31497639 DOI: 10.1021/Acsbiomaterials.8B01062  0.514
2018 Islam MA, Xu Y, Tao W, Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, et al. Author Correction: Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA. Nature Biomedical Engineering. 2: 968. PMID 31015729 DOI: 10.1038/S41551-018-0331-X  0.653
2018 Islam MA, Xu Y, Tao W, Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, et al. Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA. Nature Biomedical Engineering. 2: 850-864. PMID 31015614 DOI: 10.1038/S41551-018-0284-0  0.647
2018 Xie X, Doloff JC, Yesilyurt V, Sadraei A, McGarrigle JJ, Omami M, Veiseh O, Farah S, Isa D, Ghani S, Joshi I, Vegas A, Li J, Wang W, Bader A, ... ... Langer R, et al. Reduction of measurement noise in a continuous glucose monitor by coating the sensor with a zwitterionic polymer. Nature Biomedical Engineering. 2: 894-906. PMID 30931173 DOI: 10.1038/S41551-018-0273-3  0.773
2018 Bochenek MA, Veiseh O, Vegas AJ, McGarrigle JJ, Qi M, Marchese E, Omami M, Doloff JC, Mendoza-Elias J, Nourmohammadzadeh M, Khan A, Yeh CC, Xing Y, Isa D, Ghani S, ... ... Langer R, et al. Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques. Nature Biomedical Engineering. 2: 810-821. PMID 30873298 DOI: 10.1038/S41551-018-0275-1  0.781
2018 Shapira-Furman T, Serra R, Gorelick N, Doglioli M, Tagliaferri V, Cecia A, Peters M, Kumar A, Rottenberg Y, Langer R, Brem H, Tyler B, Domb AJ. Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer. Journal of Controlled Release : Official Journal of the Controlled Release Society. 295: 93-101. PMID 30605703 DOI: 10.1016/J.Jconrel.2018.12.048  0.337
2018 Lim JM, Cai T, Mandaric S, Chopra S, Han H, Jang S, Il Choi W, Langer R, Farokhzad OC, Karnik R. Drug loading augmentation in polymeric nanoparticles using a coaxial turbulent jet mixer: Yong investigator perspective. Journal of Colloid and Interface Science. 538: 45-50. PMID 30500466 DOI: 10.1016/J.Jcis.2018.11.029  0.749
2018 Mitchell MJ, Jain RK, Langer R. Publisher Correction: Engineering and physical sciences in oncology: challenges and opportunities. Nature Reviews. Cancer. PMID 30337715 DOI: 10.1038/S41568-018-0072-X  0.455
2018 Guimaraes PPG, Tan M, Tammela T, Wu K, Chung A, Oberli M, Wang K, Spektor R, Riley RS, Viana CTR, Jacks T, Langer R, Mitchell MJ. Potent in vivo lung cancer Wnt signaling inhibition via cyclodextrin-LGK974 inclusion complexes. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30290244 DOI: 10.1016/J.Jconrel.2018.09.025  0.739
2018 Fenton OS, Andresen JL, Paolini M, Langer R. β-Aminoacrylate Synthetic Hydrogels: Easily Accessible and Operationally Simple Biomaterials Networks. Angewandte Chemie (International Ed. in English). 57: 16026-16029. PMID 30209869 DOI: 10.1002/Anie.201808452  0.313
2018 Hayward A, Bensel T, Mazdiyasni H, Rogner J, Kirtane AR, Lee YL, Hua T, Bajpayee A, Collins J, McDonnell S, Cleveland C, Lopes A, Wahane A, Langer R, Traverso G. Scalable Gastric Resident Systems for Veterinary Application. Scientific Reports. 8: 11816. PMID 30087406 DOI: 10.1038/S41598-018-30212-3  0.778
2018 Shankar GM, Kirtane AR, Miller JJ, Mazdiyasni H, Rogner J, Tai T, Williams EA, Higuchi F, Juratli TA, Tateishi K, Koerner MVA, Tummala SS, Fink AL, Penson T, Schmidt SP, ... ... Langer R, et al. Genotype-targeted local therapy of glioma. Proceedings of the National Academy of Sciences of the United States of America. PMID 30082399 DOI: 10.1073/Pnas.1805751115  0.679
2018 Stewart MP, Langer R, Jensen KF. Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts. Chemical Reviews. PMID 30052023 DOI: 10.1021/Acs.Chemrev.7B00678  0.317
2018 Kowalski PS, Capasso Palmiero U, Huang Y, Rudra A, Langer R, Anderson DG. Ionizable Amino-Polyesters Synthesized via Ring Opening Polymerization of Tertiary Amino-Alcohols for Tissue Selective mRNA Delivery. Advanced Materials (Deerfield Beach, Fla.). e1801151. PMID 29975801 DOI: 10.1002/Adma.201801151  0.744
2018 Khan OF, Kowalski PS, Doloff JC, Tsosie JK, Bakthavatchalu V, Winn CB, Haupt J, Jamiel M, Langer R, Anderson DG. Endothelial siRNA delivery in nonhuman primates using ionizable low-molecular weight polymeric nanoparticles. Science Advances. 4: eaar8409. PMID 29963629 DOI: 10.1126/Sciadv.Aar8409  0.744
2018 Ramadi KB, Dagdeviren C, Spencer KC, Joe P, Cotler M, Rousseau E, Nunez-Lopez C, Graybiel AM, Langer R, Cima MJ. Focal, remote-controlled, chronic chemical modulation of brain microstructures. Proceedings of the National Academy of Sciences of the United States of America. PMID 29941557 DOI: 10.1073/Pnas.1804372115  0.315
2018 Mead BE, Ordovas-Montanes J, Braun AP, Levy LE, Bhargava P, Szucs MJ, Ammendolia DA, MacMullan MA, Yin X, Hughes TK, Wadsworth MH, Ahmad R, Rakoff-Nahoum S, Carr SA, Langer R, et al. Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types. Bmc Biology. 16: 62. PMID 29871632 DOI: 10.1186/S12915-018-0527-2  0.54
2018 van der Valk DC, van der Ven CFT, Blaser MC, Grolman JM, Wu PJ, Fenton OS, Lee LH, Tibbitt MW, Andresen JL, Wen JR, Ha AH, Buffolo F, van Mil A, Bouten CVC, Body SC, ... ... Langer R, et al. Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics. Nanomaterials (Basel, Switzerland). 8. PMID 29751516 DOI: 10.3390/Nano8050296  0.777
2018 Fenton OS, Olafson KN, Pillai PS, Mitchell MJ, Langer R. Advances in Biomaterials for Drug Delivery. Advanced Materials (Deerfield Beach, Fla.). e1705328. PMID 29736981 DOI: 10.1002/Adma.201705328  0.541
2018 Schneider C, Langer R, Loveday D, Hair D. Corrigendum to "Applications of ethylene vinyl acetate copolymers (EVA) in drug delivery systems" [J. Control. Release 262(2017) 284-295]. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29685764 DOI: 10.1016/J.Jconrel.2018.04.007  0.331
2018 Ayoob AM, Peppi M, Tandon V, Langer R, Borenstein JT. A fluorescence-based imaging approach to pharmacokinetic analysis of intracochlear drug delivery. Hearing Research. PMID 29661614 DOI: 10.1016/J.Heares.2018.03.026  0.309
2018 DiCiccio AM, Lee YL, Glettig DL, Walton ESE, de la Serna EL, Montgomery VA, Grant TM, Langer R, Traverso G. Caffeine-catalyzed gels. Biomaterials. 170: 127-135. PMID 29660635 DOI: 10.1016/J.Biomaterials.2018.04.010  0.341
2018 Ragelle H, Tibbitt MW, Wu SY, Castillo MA, Cheng GZ, Gangadharan SP, Anderson DG, Cima MJ, Langer R. Surface tension-assisted additive manufacturing. Nature Communications. 9: 1184. PMID 29567939 DOI: 10.1038/S41467-018-03391-W  0.557
2018 Traverso G, Kirtane AR, Schoellhammer CM, Langer R. Convergence for Translation: Drug-Delivery Research in Multidisciplinary Teams. Angewandte Chemie (International Ed. in English). PMID 29520902 DOI: 10.1002/Anie.201712512  0.69
2018 Kauffman KJ, Oberli MA, Dorkin JR, Hurtado JE, Kaczmarek JC, Bhadani S, Wyckoff J, Langer R, Jaklenec A, Anderson DG. Rapid, Single-Cell Analysis and Discovery of Vectored mRNA Transfection In Vivo with a loxP-Flanked tdTomato Reporter Mouse. Molecular Therapy. Nucleic Acids. 10: 55-63. PMID 29499956 DOI: 10.1016/J.Omtn.2017.11.005  0.542
2018 Delcassian D, Patel AK, Cortinas AB, Langer R. Drug delivery across length scales. Journal of Drug Targeting. 1-41. PMID 29415575 DOI: 10.1080/1061186X.2018.1438440  0.79
2018 Guimaraes PPG, Gaglione S, Sewastianik T, Carrasco RD, Langer R, Mitchell MJ. Nanoparticles for Immune Cytokine TRAIL-Based Cancer Therapy. Acs Nano. PMID 29378114 DOI: 10.1021/Acsnano.7B05876  0.534
2018 Yin H, Song CQ, Suresh S, Kwan SY, Wu Q, Walsh S, Ding J, Bogorad RL, Zhu LJ, Wolfe SA, Koteliansky V, Xue W, Langer R, Anderson DG. Partial DNA-guided Cas9 enables genome editing with reduced off-target activity. Nature Chemical Biology. PMID 29377001 DOI: 10.1038/Nchembio.2559  0.503
2018 Dagdeviren C, Ramadi KB, Joe P, Spencer K, Schwerdt HN, Shimazu H, Delcasso S, Amemori KI, Nunez-Lopez C, Graybiel AM, Cima MJ, Langer R. Miniaturized neural system for chronic, local intracerebral drug delivery. Science Translational Medicine. 10. PMID 29367347 DOI: 10.1126/Scitranslmed.Aan2742  0.315
2018 Kirtane AR, Abouzid O, Minahan D, Bensel T, Hill AL, Selinger C, Bershteyn A, Craig M, Mo SS, Mazdiyasni H, Cleveland C, Rogner J, Lee YL, Booth L, Javid F, ... ... Langer R, et al. Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy. Nature Communications. 9: 2. PMID 29317618 DOI: 10.1038/S41467-017-02294-6  0.682
2018 Chertok B, Langer R. Circulating Magnetic Microbubbles for Localized Real-Time Control of Drug Delivery by Ultrasonography-Guided Magnetic Targeting and Ultrasound. Theranostics. 8: 341-357. PMID 29290812 DOI: 10.7150/Thno.20781  0.645
2018 Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli M, Sánchez-Rivera F, Park Y, Liang X, Eng G, Taylor MS, Azimi R, ... ... Langer R, et al. Abstract B38: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-B38  0.564
2018 Kowalski PS, Bhattacharya C, Afewerki S, Langer R. Smart Biomaterials: Recent Advances and Future Directions Acs Biomaterials Science & Engineering. 4: 3809-3817. DOI: 10.1021/Acsbiomaterials.8B00889  0.703
2018 Traverso G, Kirtane AR, Schoellhammer CM, Langer R. Translation durch Konvergenz: Drug-Delivery-Forschung in multidisziplinären Teams Angewandte Chemie. 130: 4226-4234. DOI: 10.1002/Ange.201712512  0.685
2017 Kakkar A, Traverso G, Farokhzad OC, Weissleder R, Langer R. Evolution of macromolecular complexity in drug delivery systems. Nature Reviews. Chemistry. 1. PMID 31286060 DOI: 10.1038/s41570-017-0063  0.646
2017 Zhang S, Langer R, Traverso G. Nanoparticulate Drug Delivery Systems Targeting Inflammation for Treatment of Inflammatory Bowel Disease. Nano Today. 16: 82-96. PMID 31186671 DOI: 10.1016/J.Nantod.2017.08.006  0.315
2017 Bakh NA, Cortinas AB, Weiss MA, Langer RS, Anderson DG, Gu Z, Dutta S, Strano MS. Erratum: Glucose-responsive insulin by molecular and physical design. Nature Chemistry. 10: 109. PMID 29256502 DOI: 10.1038/Nchem.2898  0.647
2017 Bisso PW, Tai M, Katepalli H, Bertrand N, Blankschtein D, Langer R. Molecular rotors for universal quantitation of nanoscale hydrophobic interfaces in microplate format. Nano Letters. PMID 29244511 DOI: 10.1021/Acs.Nanolett.7B04877  0.541
2017 Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera F, Park YK, Liang X, Eng G, Taylor MS, Azimi R, ... ... Langer R, et al. Corrigendum: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nature Biotechnology. 35: 1211. PMID 29220013 DOI: 10.1038/Nbt1217-1211A  0.541
2017 Mikulskis P, Hook AL, Dundas A, Irvine DJ, Sanni O, Anderson DG, Langer R, Alexander MR, Williams P, Winkler DA. Prediction of Broad-spectrum Pathogen Attachment to Coating Materials for Biomedical Devices. Acs Applied Materials & Interfaces. PMID 29191009 DOI: 10.1021/Acsami.7B14197  0.536
2017 Sharma U, Concagh D, Core L, Kuang Y, You C, Pham Q, Zugates G, Busold R, Webber S, Merlo J, Langer R, Whitesides GM, Palasis M. The development of bioresorbable composite polymeric implants with high mechanical strength. Nature Materials. PMID 29180778 DOI: 10.1038/Nmat5016  0.693
2017 Rwei AY, Paris JL, Wang B, Wang W, Axon CD, Vallet-Regí M, Langer R, Kohane DS. Ultrasound-triggered local anaesthesia. Nature Biomedical Engineering. 1: 644-653. PMID 29152410 DOI: 10.1038/S41551-017-0117-6  0.642
2017 Yin H, Song CQ, Suresh S, Wu Q, Walsh S, Rhym LH, Mintzer E, Bolukbasi MF, Zhu LJ, Kauffman K, Mou H, Oberholzer A, Ding J, Kwan SY, Bogorad RL, ... ... Langer R, et al. Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing. Nature Biotechnology. PMID 29131148 DOI: 10.1038/Nbt.4005  0.538
2017 Tong Z, Martyn K, Yang A, Yin X, Mead BE, Joshi N, Sherman NE, Langer RS, Karp JM. Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells. Biomaterials. 154: 60-73. PMID 29120819 DOI: 10.1016/J.Biomaterials.2017.10.038  0.541
2017 Mitchell MJ, Jain RK, Langer R. Engineering and physical sciences in oncology: challenges and opportunities. Nature Reviews. Cancer. PMID 29026204 DOI: 10.1038/Nrc.2017.83  0.499
2017 Bertrand N, Grenier P, Mahmoudi M, Lima EM, Appel EA, Dormont F, Lim JM, Karnik R, Langer R, Farokhzad OC. Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics. Nature Communications. 8: 777. PMID 28974673 DOI: 10.1038/S41467-017-00600-W  0.796
2017 Bakh NA, Cortinas AB, Weiss MA, Langer RS, Anderson DG, Gu Z, Dutta S, Strano MS. Glucose-responsive insulin by molecular and physical design. Nature Chemistry. 9: 937-943. PMID 28937662 DOI: 10.1038/Nchem.2857  0.67
2017 Ding X, Stewart M, Sharei A, Weaver JC, Langer RS, Jensen KF. High-throughput Nuclear Delivery and Rapid Expression of DNA via Mechanical and Electrical Cell-Membrane Disruption. Nature Biomedical Engineering. 1. PMID 28932622 DOI: 10.1038/S41551-017-0039  0.527
2017 Mahmoudi M, Yu M, Serpooshan V, Wu JC, Langer R, Lee RT, Karp JM, Farokhzad OC. Multiscale technologies for treatment of ischemic cardiomyopathy. Nature Nanotechnology. 12: 845-855. PMID 28875984 DOI: 10.1038/Nnano.2017.167  0.71
2017 Webber MJ, Langer R. Drug delivery by supramolecular design. Chemical Society Reviews. PMID 28828455 DOI: 10.1039/C7Cs00391A  0.707
2017 Schneider C, Langer R, Loveday D, Hair D. Applications of ethylene vinyl acetate copolymers (EVA) in drug delivery systems. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28789964 DOI: 10.1016/J.Jconrel.2017.08.004  0.35
2017 Caffarel-Salvador E, Abramson A, Langer R, Traverso G. Oral delivery of biologics using drug-device combinations. Current Opinion in Pharmacology. 36: 8-13. PMID 28779684 DOI: 10.1016/J.Coph.2017.07.003  0.327
2017 Liu J, Pang Y, Zhang S, Cleveland C, Yin X, Booth L, Lin J, Lucy Lee YA, Mazdiyasni H, Saxton S, Kirtane AR, Erlach TV, Rogner J, Langer R, Traverso G. Triggerable tough hydrogels for gastric resident dosage forms. Nature Communications. 8: 124. PMID 28743858 DOI: 10.1038/S41467-017-00144-Z  0.699
2017 Yu D, Khan OF, Suvà ML, Dong B, Panek WK, Xiao T, Wu M, Han Y, Ahmed AU, Balyasnikova IV, Zhang HF, Sun C, Langer R, Anderson DG, Lesniak MS. Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression. Proceedings of the National Academy of Sciences of the United States of America. PMID 28696296 DOI: 10.1073/Pnas.1701911114  0.547
2017 Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E, Clark JW, Willett CG, Luster AD, Yun SH, Langer R, Anderson DG, Padera TP, Jain RK, et al. Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy. The Journal of Clinical Investigation. PMID 28691930 DOI: 10.1172/Jci93182  0.514
2017 Fenton OS, Kauffman KJ, Kaczmarek JC, McClellan RL, Jhunjhunwala S, Tibbitt MW, Zeng MD, Appel EA, Dorkin JR, Mir FF, Yang JH, Oberli MA, Heartlein MW, DeRosa F, Langer R, et al. Synthesis and Biological Evaluation of Ionizable Lipid Materials for the In Vivo Delivery of Messenger RNA to B Lymphocytes. Advanced Materials (Deerfield Beach, Fla.). PMID 28681930 DOI: 10.1002/Adma.201606944  0.791
2017 Yang NJ, Kauke MJ, Sun F, Yang LF, Maass KF, Traxlmayr MW, Yu Y, Xu Y, Langer RS, Anderson DG, Wittrup KD. Cytosolic delivery of siRNA by ultra-high affinity dsRNA binding proteins. Nucleic Acids Research. PMID 28641400 DOI: 10.1093/Nar/Gkx546  0.566
2017 Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera F, Park YK, Liang X, Eng G, Taylor MS, Azimi R, ... ... Langer R, et al. In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nature Biotechnology. PMID 28459449 DOI: 10.1038/Nbt.3836  0.566
2017 Nadeau P, El-Damak D, Glettig D, Kong YL, Mo S, Cleveland C, Booth L, Roxhed N, Langer R, Chandrakasan AP, Traverso G. Prolonged energy harvesting for ingestible devices. Nature Biomedical Engineering. 1. PMID 28458955 DOI: 10.1038/S41551-016-0022  0.704
2017 Ragelle H, Naba A, Larson BL, Zhou F, Prijić M, Whittaker CA, Del Rosario A, Langer R, Hynes RO, Anderson DG. Comprehensive proteomic characterization of stem cell-derived extracellular matrices. Biomaterials. 128: 147-159. PMID 28327460 DOI: 10.1016/J.Biomaterials.2017.03.008  0.549
2017 Doloff JC, Veiseh O, Vegas AJ, Tam HH, Farah S, Ma M, Li J, Bader A, Chiu A, Sadraei A, Aresta-Dasilva S, Griffin M, Jhunjhunwala S, Webber M, Siebert S, ... ... Langer R, et al. Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates. Nature Materials. PMID 28319612 DOI: 10.1038/Nmat4866  0.785
2017 Mitchell MJ, Webster J, Chung A, Guimarães PP, Khan OF, Langer R. Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis. Nature Communications. 8: 14179. PMID 28317839 DOI: 10.1038/Ncomms14179  0.523
2017 Yesilyurt V, Ayoob AM, Appel EA, Borenstein JT, Langer R, Anderson DG. Mixed Reversible Covalent Crosslink Kinetics Enable Precise, Hierarchical Mechanical Tuning of Hydrogel Networks. Advanced Materials (Deerfield Beach, Fla.). PMID 28295624 DOI: 10.1002/Adma.201605947  0.684
2017 Oberli MA, Reichmuth AM, Dorkin JR, Mitchell MJ, Fenton OS, Jaklenec A, Anderson DG, Langer R, Blankschtein D. Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy. Nano Letters. 17: 1326-1335. PMID 28273716 DOI: 10.1021/Acs.Nanolett.6B03329  0.715
2017 McLean WJ, Yin X, Lu L, Lenz DR, McLean D, Langer R, Karp JM, Edge AS. Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory Hair Cells. Cell Reports. 18: 1917-1929. PMID 28228258 DOI: 10.1016/J.Celrep.2017.01.066  0.532
2017 Dahlman JE, Kauffman KJ, Xing Y, Shaw TE, Mir FF, Dlott CC, Langer R, Anderson DG, Wang ET. Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics. Proceedings of the National Academy of Sciences of the United States of America. PMID 28167778 DOI: 10.1073/Pnas.1620874114  0.565
2017 Schoellhammer CM, Lauwers GY, Goettel JA, Oberli MA, Cleveland C, Park JY, Minahan D, Chen Y, Anderson DG, Jaklenec A, Snapper SB, Langer R, Traverso G. Ultrasound-Mediated Delivery of RNA to Colonic Mucosa of Live Mice. Gastroenterology. PMID 28088460 DOI: 10.1053/J.Gastro.2017.01.002  0.55
2017 Mitchell MJ, Langer R. Abstract PR09: Polymeric mechanical amplifiers of tumor apoptosis Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-Pr09  0.459
2017 Langer RS. Abstract IA02: Advances in drug delivery Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-Ia02  0.336
2017 Karinja SJ, Veiseh O, Bernstein JL, Jin JL, Abadeer AI, Kaymakcalan O, Premaratne I, Langer R, Anderson DG, Spector JA. Abstract Plastic and Reconstructive Surgery - Global Open. 5: 54-55. DOI: 10.1097/01.Gox.0000526239.19110.57  0.461
2017 Karinja SJ, Veiseh O, Bernstein J, Akintayo R, Jin J, Dong X, Abadeer A, Kaymakcalan O, Morrison KA, Langer RS, Anderson DG, Spector JA. Abstract 130 Plastic and Reconstructive Surgery - Global Open. 5: 96. DOI: 10.1097/01.Gox.0000516649.46212.A5  0.461
2017 Karinja SJ, Veiseh O, Bernstein J, Akintayo R, Jin J, Dong X, Abadeer A, Kaymakcalan O, Morrison KA, Langer RS, Anderson DG, Spector JA. Abstract 15. Better Living through Chemistry Plastic and Reconstructive Surgery - Global Open. 5: 29. DOI: 10.1097/01.Gox.0000513430.71277.57  0.488
2017 Yu D, Khan OF, Suvà ML, Panek WK, Wu M, Han Y, Ahmed AU, Balyasnikova IV, Anderson DG, Langer R, Lesniak MS. OS06.2 Combination RNAi therapy against glioma stem cells via sustained lipopolymeric nanoparticle delivery delays tumor progression Neuro-Oncology. 19: iii11-iii11. DOI: 10.1093/Neuonc/Nox036.036  0.539
2016 Chu H, Kohane DS, Langer R. RNA therapeutics - The potential treatment for myocardial infarction. Regenerative Therapy. 4: 83-91. PMID 31245491 DOI: 10.1016/J.Reth.2016.03.002  0.642
2016 Zhang YS, Duchamp M, Oklu R, Ellisen LW, Langer R, Khademhosseini A. Bioprinting the Cancer Microenvironment. Acs Biomaterials Science & Engineering. 2: 1710-1721. PMID 28251176 DOI: 10.1021/Acsbiomaterials.6B00246  0.641
2016 Yesilyurt V, Veiseh O, Doloff JC, Li J, Bose S, Xie X, Bader AR, Chen M, Webber MJ, Vegas AJ, Langer R, Anderson DG. A Facile and Versatile Method to Endow Biomaterial Devices with Zwitterionic Surface Coatings. Advanced Healthcare Materials. PMID 27976536 DOI: 10.1002/Adhm.201601091  0.784
2016 Morgan KY, Sklaviadis D, Tochka ZL, Fischer KM, Hearon K, Morgan TD, Langer R, Freed LE. Multi-Material Tissue Engineering Scaffold with Hierarchical Pore Architecture. Advanced Functional Materials. 26: 5873-5883. PMID 27942257 DOI: 10.1002/Adfm.201601146  0.31
2016 Luo X, Wang W, Dorkin JR, Veiseh O, Chang PH, Abutbul-Ionita I, Danino D, Langer R, Anderson DG, Dong Y. Poly(glycoamidoamine) brush nanomaterials for systemic siRNA delivery in vivo. Biomaterials Science. PMID 27921096 DOI: 10.1039/C6Bm00683C  0.592
2016 Yu AC, Chen H, Chan D, Agmon G, Stapleton LM, Sevit AM, Tibbitt MW, Acosta JD, Zhang T, Franzia PW, Langer R, Appel EA. Scalable manufacturing of biomimetic moldable hydrogels for industrial applications. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911849 DOI: 10.1073/Pnas.1618156113  0.602
2016 Webber MJ, Appel EA, Vinciguerra B, Cortinas AB, Thapa LS, Jhunjhunwala S, Isaacs L, Langer R, Anderson DG. Supramolecular PEGylation of biopharmaceuticals. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911829 DOI: 10.1073/Pnas.1616639113  0.792
2016 Bellinger AM, Jafari M, Grant TM, Zhang S, Slater HC, Wenger EA, Mo S, Lee YL, Mazdiyasni H, Kogan L, Barman R, Cleveland C, Booth L, Bensel T, Minahan D, ... ... Langer R, et al. Oral, ultra-long-lasting drug delivery: Application toward malaria elimination goals. Science Translational Medicine. 8: 365ra157. PMID 27856796 DOI: 10.1126/Scitranslmed.Aag2374  0.312
2016 Kirtane AR, Langer R, Traverso G. Progress in Formulation-Based Approaches for Antiretrovirals. Journal of Pharmaceutical Sciences. PMID 27771050 DOI: 10.1016/J.Xphs.2016.09.015  0.696
2016 Stewart MP, Sharei A, Ding X, Sahay G, Langer R, Jensen KF. In vitro and ex vivo strategies for intracellular delivery. Nature. 538: 183-192. PMID 27734871 DOI: 10.1038/Nature19764  0.774
2016 Ragelle H, Danhier F, Préat V, Langer R, Anderson DG. Nanoparticle-based drug delivery systems: a commercial and regulatory outlook as the field matures. Expert Opinion On Drug Delivery. PMID 27730820 DOI: 10.1080/17425247.2016.1244187  0.549
2016 Tam HH, Melo MB, Kang M, Pelet JM, Ruda VM, Foley MH, Hu JK, Kumari S, Crampton J, Baldeon AD, Sanders RW, Moore JP, Crotty S, Langer R, Anderson DG, et al. Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination. Proceedings of the National Academy of Sciences of the United States of America. PMID 27702895 DOI: 10.1073/Pnas.1606050113  0.618
2016 Yun S, Budatha M, Dahlman JE, Coon BG, Cameron RT, Langer R, Anderson DG, Baillie G, Schwartz MA. Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling. Nature Cell Biology. PMID 27595237 DOI: 10.1038/Ncb3405  0.514
2016 Saung MT, Sharei A, Adalsteinsson VA, Cho N, Kamath T, Ruiz C, Kirkpatrick J, Patel N, Mino-Kenudson M, Thayer SP, Langer R, Jensen KF, Liss AS, Love JC. A Size-Selective Intracellular Delivery Platform. Small (Weinheim An Der Bergstrasse, Germany). PMID 27594517 DOI: 10.1002/Smll.201601155  0.319
2016 Khademhosseini A, Langer R. A decade of progress in tissue engineering. Nature Protocols. 11: 1775-81. PMID 27583639 DOI: 10.1038/Nprot.2016.123  0.543
2016 Chertok B, Langer R, Anderson DG. Spatial Control of Gene Expression by Nanocarriers Using Heparin Masking and Ultrasound-Targeted Microbubble Destruction. Acs Nano. PMID 27472268 DOI: 10.1021/Acsnano.6B01199  0.718
2016 Hammad M, Rao W, Smith JG, Anderson DG, Langer R, Young LE, Barrett DA, Davies MC, Denning C, Alexander MR. Identification of polymer surface adsorbed proteins implicated in pluripotent human embryonic stem cell expansion. Biomaterials Science. PMID 27466628 DOI: 10.1039/C6Bm00214E  0.549
2016 Adlington K, Nguyen NT, Eaves E, Yang J, Chang CY, Li J, Gower AL, Stimpson A, Anderson DG, Langer R, Davies MC, Hook AL, Williams P, Alexander MR, Irvine DJ. Application of Targeted Molecular and Material Property Optimization to Bacterial Attachment-Resistant (Meth)acrylate Polymers. Biomacromolecules. PMID 27461341 DOI: 10.1021/Acs.Biomac.6B00615  0.553
2016 Dong Y, Wang W, Veiseh O, Appel EA, Xue K, Webber MJ, Tang B, Yang XW, Weir G, Langer R, Anderson DG. Injectable and glucose-responsive hydrogels based on boronic acid-glucose complexation. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 27455412 DOI: 10.1021/Acs.Langmuir.5B04755  0.783
2016 Chahal JS, Khan OF, Cooper CL, McPartlan JS, Tsosie JK, Tilley LD, Sidik SM, Lourido S, Langer R, Bavari S, Ploegh HL, Anderson DG. Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose. Proceedings of the National Academy of Sciences of the United States of America. PMID 27382155 DOI: 10.1073/Pnas.1600299113  0.511
2016 Kanasty RL, Vegas AJ, Ceo LM, Maier M, Charisse K, Nair JK, Langer R, Anderson DG. Sequence-Defined Oligomers from Hydroxyproline Building Blocks for Parallel Synthesis Applications. Angewandte Chemie (International Ed. in English). PMID 27365192 DOI: 10.1002/Anie.201602748  0.788
2016 Farah S, Anderson DG, Langer R. Physical and Mechanical Properties of PLA, and their Functions in Widespread Applications - a Comprehensive Review. Advanced Drug Delivery Reviews. PMID 27356150 DOI: 10.1016/J.Addr.2016.06.012  0.558
2016 Hong AL, Tseng YY, Cowley GS, Jonas O, Cheah JH, Kynnap BD, Doshi MB, Oh C, Meyer SC, Church AJ, Gill S, Bielski CM, Keskula P, Imamovic A, Howell S, ... ... Langer RS, et al. Integrated genetic and pharmacologic interrogation of rare cancers. Nature Communications. 7: 11987. PMID 27329820 DOI: 10.1038/Ncomms11987  0.423
2016 Jonas O, Calligaris D, Methuku KR, Poe MM, Francois JP, Tranghese F, Changelian A, Sieghart W, Ernst M, Krummel DA, Cook JM, Pomeroy SL, Cima M, Agar NY, Langer R, et al. First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development. Journal of Biomedical Nanotechnology. 12: 1297-302. PMID 27319222 DOI: 10.1166/Jbn.2016.2262  0.305
2016 Vegas AJ, Veiseh O, Doloff JC, Ma M, Tam HH, Bratlie K, Li J, Bader AR, Langan E, Olejnik K, Fenton P, Kang JW, Hollister-Locke J, Bochenek MA, Chiu A, ... ... Langer R, et al. Corrigendum: Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates. Nature Biotechnology. 34: 666. PMID 27281428 DOI: 10.1038/Nbt0616-666E  0.767
2016 Sager HB, Dutta P, Dahlman JE, Hulsmans M, Courties G, Sun Y, Heidt T, Vinegoni C, Borodovsky A, Fitzgerald K, Wojtkiewicz GR, Iwamoto Y, Tricot B, Khan OF, Kauffman KJ, ... ... Langer R, et al. RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction. Science Translational Medicine. 8: 342ra80. PMID 27280687 DOI: 10.1126/Scitranslmed.Aaf1435  0.535
2016 Zhao X, Hwang NS, Bichara DA, Saris DB, Malda J, Vacanti JP, Pomerantseva I, Sundback CA, Langer R, Anderson DG, Randolph MA. Chondrogenesis by bone marrow-derived mesenchymal stem cells grown in chondrocyte-conditioned medium for auricular reconstruction. Journal of Tissue Engineering and Regenerative Medicine. PMID 27256796 DOI: 10.1002/Term.2171  0.629
2016 Yu B, Kang SY, Akthakul A, Ramadurai N, Pilkenton M, Patel A, Nashat A, Anderson DG, Sakamoto FH, Gilchrest BA, Anderson RR, Langer R. An elastic second skin. Nature Materials. PMID 27159017 DOI: 10.1038/Nmat4635  0.531
2016 Xue Y, Xu X, Zhang XQ, Farokhzad OC, Langer R. Preventing diet-induced obesity in mice by adipose tissue transformation and angiogenesis using targeted nanoparticles. Proceedings of the National Academy of Sciences of the United States of America. PMID 27140638 DOI: 10.1073/Pnas.1603840113  0.542
2016 Indolfi L, Ligorio M, Ting DT, Xega K, Tzafriri AR, Bersani F, Aceto N, Thapar V, Fuchs BC, Deshpande V, Baker AB, Ferrone CR, Haber DA, Langer R, Clark JW, et al. A tunable delivery platform to provide local chemotherapy for pancreatic ductal adenocarcinoma. Biomaterials. 93: 71-82. PMID 27082874 DOI: 10.1016/J.Biomaterials.2016.03.044  0.599
2016 Reichmuth AM, Oberli MA, Jeklenec A, Langer R, Blankschtein D. mRNA vaccine delivery using lipid nanoparticles. Therapeutic Delivery. 7: 319-34. PMID 27075952 DOI: 10.4155/Tde-2016-0006  0.523
2016 Vegas AJ, Veiseh O, G M, Millman JR, Pagliuca FW, Bader AR, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, ... ... Langer R, et al. Corrigendum: Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice. Nature Medicine. 22: 446. PMID 27050590 DOI: 10.1038/Nm0416-446E  0.774
2016 Jhunjhunwala S, Alvarez D, Aresta-DaSilva S, Tang K, Tang BC, Greiner DL, Newburger PE, von Andrian UH, Langer R, Anderson DG. Splenic progenitors aid in maintaining high neutrophil numbers at sites of sterile chronic inflammation. Journal of Leukocyte Biology. PMID 26965635 DOI: 10.1189/Jlb.1Hi0615-248Rr  0.72
2016 Fischer KM, Morgan KY, Hearon K, Sklaviadis D, Tochka ZL, Fenton OS, Anderson DG, Langer R, Freed LE. Poly(Limonene Thioether) Scaffold for Tissue Engineering. Advanced Healthcare Materials. PMID 26890480 DOI: 10.1002/Adhm.201500892  0.575
2016 Fenton OS, Kauffman KJ, McClellan RL, Appel EA, Dorkin JR, Tibbitt MW, Heartlein MW, DeRosa F, Langer R, Anderson DG. Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery. Advanced Materials (Deerfield Beach, Fla.). PMID 26889757 DOI: 10.1002/Adma.201505822  0.695
2016 Yin H, Song CQ, Dorkin JR, Zhu LJ, Li Y, Wu Q, Park A, Yang J, Suresh S, Bizhanova A, Gupta A, Bolukbasi MF, Walsh S, Bogorad RL, Gao G, ... ... Langer R, et al. Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo. Nature Biotechnology. PMID 26829318 DOI: 10.1038/Nbt.3471  0.547
2016 Oudin MJ, Jonas O, Kosciuk T, Broye LC, Guido BC, Wyckoff J, Riquelme D, Lamar JM, Asokan SB, Whittaker C, Ma D, Langer R, Cima MJ, Wisinski KB, Hynes RO, et al. Tumor cell-driven extracellular matrix remodeling enables haptotaxis during metastatic progression. Cancer Discovery. PMID 26811325 DOI: 10.1158/2159-8290.Cd-15-1183  0.445
2016 Vegas AJ, Veiseh O, Gürtler M, Millman JR, Pagliuca FW, Bader AR, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, ... ... Langer R, et al. Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice. Nature Medicine. PMID 26808346 DOI: 10.1038/Nm.4030  0.792
2016 Vegas AJ, Veiseh O, Doloff JC, Ma M, Tam HH, Bratlie K, Li J, Bader AR, Langan E, Olejnik K, Fenton P, Kang JW, Hollister-Locke J, Bochenek MA, Chiu A, ... ... Langer R, et al. Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates. Nature Biotechnology. PMID 26807527 DOI: 10.1038/Nbt.3462  0.787
2016 Yin X, Mead BE, Safaee H, Langer R, Karp JM, Levy O. Engineering Stem Cell Organoids. Cell Stem Cell. 18: 25-38. PMID 26748754 DOI: 10.1016/J.Stem.2015.12.005  0.549
2016 Tibbitt MW, Dahlman JE, Langer R. Emerging Frontiers in Drug Delivery. Journal of the American Chemical Society. PMID 26741786 DOI: 10.1021/Jacs.5B09974  0.32
2016 Dong Y, Dorkin JR, Wang W, Chang PH, Webber MJ, Tang BC, Yang J, Abutbul-Ionita I, Danino D, DeRosa F, Heartlein M, Langer R, Anderson DG. Poly(glycoamidoamine) brushes formulated nanomaterials for systemic siRNA and mRNA delivery in vivo. Nano Letters. PMID 26727632 DOI: 10.1021/Acs.Nanolett.5B02428  0.766
2016 Hong AL, Tseng Y, Cowley G, Jonas O, Cheah J, Doshi M, Kynnap B, Oy C, Keskula P, Kryukov G, Cima M, Langer R, Schreiber S, Root D, Boehm J, et al. Abstract PR04: Integration of CRISPR-Cas9, RNAi and pharmacologic screens identify actionable targets in a rare cancer Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Pdx16-Pr04  0.426
2016 Oudin MJ, Jonas O, Kosciuk T, Broye L, Wyckoff J, Klazen J, Lamar J, Asokan S, Whittaker C, Langer R, Cima M, Wisinski K, Hynes R, Lauffenburger D, Keely P, et al. Abstract PR15: Haptotaxis and direct remodeling of the extracellular matrix by tumor cells is important for metastasis Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-Pr15  0.456
2016 Hong AL, Cowley GS, Tseng Y, Cheah JH, Jonas O, Doshi MB, Kynnap BD, Oh C, Meyer S, Clemons P, Burger M, Vazquez F, Weir B, Kryukov GV, Church A, ... ... Langer R, et al. Abstract B38: Developing a functional genomics platform to interrogate rare pediatric cancers Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-B38  0.437
2016 Mitchell MJ, Langer R. Abstract 3901: Polymeric mechanical amplifiers of tumor cell receptor-mediated apoptosis Cancer Research. 76: 3901-3901. DOI: 10.1158/1538-7445.Am2016-3901  0.5
2016 Sharei A, Gilbert J, Irvine D, Jensen K, Langer R. Abstract 2293: Vector-free engineering of immune cells for adoptive cell therapy Cancer Research. 76: 2293-2293. DOI: 10.1158/1538-7445.Am2016-2293  0.543
2016 Schoellhammer CM, Schroeder A, Maa R, Lauwers GY, Swiston A, Zervas M, Barman R, DiCiccio AM, Brugge WR, Anderson DG, Blankschtein D, Langer R, Traverso G. Low-frequency ultrasound for the delivery of therapeutics to the gastrointestinal tract The Journal of the Acoustical Society of America. 139: 2091-2092. DOI: 10.1121/1.4950206  0.68
2016 Anselmo AC, McHugh KJ, Webster J, Langer R, Jaklenec A. Biomaterials: Layer‐by‐Layer Encapsulation of Probiotics for Delivery to the Microbiome (Adv. Mater. 43/2016) Advanced Materials. 28: 9442-9442. DOI: 10.1002/Adma.201670300  0.336
2015 Appel EA, Tibbitt MW, Greer JM, Fenton OS, Kreuels K, Anderson DG, Langer R. Exploiting Electrostatic Interactions in Polymer-Nanoparticle Hydrogels. Acs Macro Letters. 4: 848-852. PMID 35596508 DOI: 10.1021/acsmacrolett.5b00416  0.689
2015 Webber MJ, Anderson DG, Langer R. Engineering Synthetically Modified Insulin for Glucose-Responsive Diabetes Therapy. Expert Review of Endocrinology & Metabolism. 10: 483-489. PMID 27570535 DOI: 10.1586/17446651.2015.1071187  0.726
2015 Chung BL, Toth MJ, Kamaly N, Sei YJ, Becraft J, Mulder WJ, Fayad ZA, Farokhzad OC, Kim Y, Langer R. Nanomedicines for Endothelial Disorders. Nano Today. 10: 759-776. PMID 26955397 DOI: 10.1016/J.Nantod.2015.11.009  0.635
2015 Lee Y, Xu C, Sebastin M, Lee A, Holwell N, Xu C, Miranda Nieves D, Mu L, Langer RS, Lin C, Karp JM. Medical Adhesives: Bioinspired Nanoparticulate Medical Glues for Minimally Invasive Tissue Repair (Adv. Healthcare Mater. 16/2015). Advanced Healthcare Materials. 4: 2318. PMID 26767735 DOI: 10.1002/Adhm.201570092  0.748
2015 Jaklenec A, Anselmo AC, Hong J, Vegas A, Kozminsky M, Langer R, Hammond PT, Anderson DG. High Throughput Layer-by-Layer Films for Extracting Film Forming Parameters and Modulating Film Interactions with Cells. Acs Applied Materials & Interfaces. PMID 26713554 DOI: 10.1021/Acsami.5B11081  0.756
2015 Langer R, Vacanti J. Advances in tissue engineering. Journal of Pediatric Surgery. 51: 8-12. PMID 26711689 DOI: 10.1016/J.Jpedsurg.2015.10.022  0.478
2015 Webber MJ, Appel EA, Meijer EW, Langer R. Supramolecular biomaterials. Nature Materials. 15: 13-26. PMID 26681596 DOI: 10.1038/nmat4474  0.759
2015 Yin H, Bogorad RL, Barnes C, Walsh S, Zhuang I, Nonaka H, Ruda V, Kuchimanchi S, Nechev L, Akinc A, Xue W, Zerial M, Langer R, Anderson DG, Koteliansky V. Control of liver size by RNAi-mediated multiplex knockdown and its application for discovery of regulatory mechanisms. Journal of Hepatology. PMID 26658687 DOI: 10.1016/J.Jhep.2015.11.028  0.503
2015 Rwei AY, Lee JJ, Zhan C, Liu Q, Ok MT, Shankarappa SA, Langer R, Kohane DS. Repeatable and adjustable on-demand sciatic nerve block with phototriggerable liposomes. Proceedings of the National Academy of Sciences of the United States of America. PMID 26644576 DOI: 10.1073/Pnas.1518791112  0.776
2015 Lim DK, Wylie RG, Langer R, Kohane DS. Selective binding of C-6 OH sulfated hyaluronic acid to the angiogenic isoform of VEGF165. Biomaterials. 77: 130-138. PMID 26588795 DOI: 10.1016/J.Biomaterials.2015.10.074  0.655
2015 Yesilyurt V, Webber MJ, Appel EA, Godwin C, Langer R, Anderson DG. Injectable Self-Healing Glucose-Responsive Hydrogels with pH-Regulated Mechanical Properties. Advanced Materials (Deerfield Beach, Fla.). PMID 26540021 DOI: 10.1002/Adma.201502902  0.786
2015 Langer R. Chemical materials and their regulation of the movement of molecules. Quarterly Reviews of Biophysics. 48: 424-8. PMID 26537401 DOI: 10.1017/S0033583515000165  0.301
2015 Schoellhammer CM, Schroeder A, Maa R, Lauwers GY, Swiston A, Zervas M, Barman R, DiCiccio AM, Brugge WR, Anderson DG, Blankschtein D, Langer R, Traverso G. Ultrasound-mediated gastrointestinal drug delivery. Science Translational Medicine. 7: 310ra168. PMID 26491078 DOI: 10.1126/Scitranslmed.Aaa5937  0.681
2015 Jhunjhunwala S, Aresta-DaSilva S, Tang K, Alvarez D, Webber MJ, Tang BC, Lavin DM, Veiseh O, Doloff JC, Bose S, Vegas A, Ma M, Sahay G, Chiu A, Bader A, ... ... Langer R, et al. Neutrophil Responses to Sterile Implant Materials. Plos One. 10: e0137550. PMID 26355958 DOI: 10.1371/Journal.Pone.0137550  0.771
2015 Zhang S, Ermann J, Succi MD, Zhou A, Hamilton MJ, Cao B, Korzenik JR, Glickman JN, Vemula PK, Glimcher LH, Traverso G, Langer R, Karp JM. An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease. Science Translational Medicine. 7: 300ra128. PMID 26268315 DOI: 10.1126/Scitranslmed.Aaa5657  0.564
2015 Lee Y, Xu C, Sebastin M, Lee A, Holwell N, Xu C, Miranda Nieves D, Mu L, Langer RS, Lin C, Karp JM. Bioinspired Nanoparticulate Medical Glues for Minimally Invasive Tissue Repair. Advanced Healthcare Materials. PMID 26227833 DOI: 10.1002/Adhm.201500419  0.787
2015 Zhang S, Bellinger AM, Glettig DL, Barman R, Lee YL, Zhu J, Cleveland C, Montgomery VA, Gu L, Nash LD, Maitland DJ, Langer R, Traverso G. A pH-responsive supramolecular polymer gel as an enteric elastomer for use in gastric devices. Nature Materials. PMID 26213897 DOI: 10.1038/Nmat4355  0.589
2015 Stary G, Olive A, Radovic-Moreno AF, Gondek D, Alvarez D, Basto PA, Perro M, Vrbanac VD, Tager AM, Shi J, Yethon JA, Farokhzad OC, Langer R, Starnbach MN, Von Andrian UH. A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells Science. 348. PMID 26089520 DOI: 10.1126/Science.Aaa8205  0.497
2015 O'Shea TM, Webber MJ, Aimetti AA, Langer R. Covalent Incorporation of Trehalose within Hydrogels for Enhanced Long-Term Functional Stability and Controlled Release of Biomacromolecules. Advanced Healthcare Materials. 4: 1802-12. PMID 26088467 DOI: 10.1002/Adhm.201500334  0.679
2015 Celiz AD, Smith JG, Patel AK, Hook AL, Rajamohan D, George VT, Flatt L, Patel MJ, Epa VC, Singh T, Langer R, Anderson DG, Allen ND, Hay DC, Winkler DA, et al. Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation. Advanced Materials (Deerfield Beach, Fla.). 27: 4006-12. PMID 26033422 DOI: 10.1002/Adma.201501351  0.489
2015 Patel AK, Celiz AD, Rajamohan D, Anderson DG, Langer R, Davies MC, Alexander MR, Denning C. A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarrays. Biomaterials. 61: 257-65. PMID 26005764 DOI: 10.1016/J.Biomaterials.2015.05.019  0.573
2015 Lee Szeto G, Van Egeren D, Worku H, Sharei A, Alejandro B, Park C, Frew K, Brefo M, Mao S, Heimann M, Langer R, Jensen K, Irvine DJ. Microfluidic squeezing for intracellular antigen loading in polyclonal B-cells as cellular vaccines. Scientific Reports. 5: 10276. PMID 25999171 DOI: 10.1038/Srep10276  0.504
2015 Veiseh O, Doloff JC, Ma M, Vegas AJ, Tam HH, Bader AR, Li J, Langan E, Wyckoff J, Loo WS, Jhunjhunwala S, Chiu A, Siebert S, Tang K, Hollister-Lock J, ... ... Langer R, et al. Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates. Nature Materials. 14: 643-51. PMID 25985456 DOI: 10.1038/Nmat4290  0.792
2015 Jonas O, Landry HM, Fuller JE, Santini JT, Baselga J, Tepper RI, Cima MJ, Langer R. An implantable microdevice to perform high-throughput in vivo drug sensitivity testing in tumors. Science Translational Medicine. 7: 284ra57. PMID 25904741 DOI: 10.1126/Scitranslmed.3010564  0.301
2015 Hong CA, Eltoukhy AA, Lee H, Langer R, Anderson DG, Nam YS. Dendrimeric siRNA for Efficient Gene Silencing. Angewandte Chemie (International Ed. in English). 54: 6740-4. PMID 25892329 DOI: 10.1002/Anie.201412493  0.539
2015 Sharei A, Trifonova R, Jhunjhunwala S, Hartoularos GC, Eyerman AT, Lytton-Jean A, Angin M, Sharma S, Poceviciute R, Mao S, Heimann M, Liu S, Talkar T, Khan OF, Addo M, ... ... Langer R, et al. Ex vivo cytosolic delivery of functional macromolecules to immune cells. Plos One. 10: e0118803. PMID 25875117 DOI: 10.1371/Journal.Pone.0118803  0.79
2015 Sydlik SA, Jhunjhunwala S, Webber MJ, Anderson DG, Langer R. In vivo compatibility of graphene oxide with differing oxidation states. Acs Nano. 9: 3866-74. PMID 25849074 DOI: 10.1021/Acsnano.5B01290  0.784
2015 White K, Lu Y, Annis S, Hale AE, Chau BN, Dahlman JE, Hemann C, Opotowsky AR, Vargas SO, Rosas I, Perrella MA, Osorio JC, Haley KJ, Graham BB, Kumar R, ... ... Langer R, et al. Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension. Embo Molecular Medicine. 7: 695-713. PMID 25825391 DOI: 10.15252/Emmm.201404511  0.486
2015 Khan OF, Zaia EW, Jhunjhunwala S, Xue W, Cai W, Yun DS, Barnes CM, Dahlman JE, Dong Y, Pelet JM, Webber MJ, Tsosie JK, Jacks TE, Langer R, Anderson DG. Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature. Nano Letters. 15: 3008-16. PMID 25789998 DOI: 10.1021/Nl5048972  0.788
2015 Appel EA, Tibbitt MW, Webber MJ, Mattix BA, Veiseh O, Langer R. Self-assembled hydrogels utilizing polymer-nanoparticle interactions. Nature Communications. 6: 6295. PMID 25695516 DOI: 10.1038/Ncomms7295  0.772
2015 Chou DH, Webber MJ, Tang BC, Lin AB, Thapa LS, Deng D, Truong JV, Cortinas AB, Langer R, Anderson DG. Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates. Proceedings of the National Academy of Sciences of the United States of America. 112: 2401-6. PMID 25675515 DOI: 10.1073/Pnas.1424684112  0.766
2015 Schoellhammer CM, Srinivasan S, Barman R, Mo SH, Polat BE, Langer R, Blankschtein D. Applicability and safety of dual-frequency ultrasonic treatment for the transdermal delivery of drugs. Journal of Controlled Release : Official Journal of the Controlled Release Society. 202: 93-100. PMID 25662228 DOI: 10.1016/J.Jconrel.2015.02.002  0.534
2015 Sanchez-Gaytan BL, Fay F, Lobatto ME, Tang J, Ouimet M, Kim Y, van der Staay SE, van Rijs SM, Priem B, Zhang L, Fisher EA, Moore KJ, Langer R, Fayad ZA, Mulder WJ. HDL-mimetic PLGA nanoparticle to target atherosclerosis plaque macrophages. Bioconjugate Chemistry. 26: 443-51. PMID 25650634 DOI: 10.1021/Bc500517K  0.306
2015 Maldonado RA, LaMothe RA, Ferrari JD, Zhang AH, Rossi RJ, Kolte PN, Griset AP, O'Neil C, Altreuter DH, Browning E, Johnston L, Farokhzad OC, Langer R, Scott DW, von Andrian UH, et al. Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance. Proceedings of the National Academy of Sciences of the United States of America. 112: E156-65. PMID 25548186 DOI: 10.1073/Pnas.1408686111  0.545
2015 Wang Q, Cheng H, Peng H, Zhou H, Li PY, Langer R. Non-genetic engineering of cells for drug delivery and cell-based therapy. Advanced Drug Delivery Reviews. 91: 125-40. PMID 25543006 DOI: 10.1016/J.Addr.2014.12.003  0.433
2015 Sanni O, Chang CY, Anderson DG, Langer R, Davies MC, Williams PM, Williams P, Alexander MR, Hook AL. Bacterial attachment to polymeric materials correlates with molecular flexibility and hydrophilicity. Advanced Healthcare Materials. 4: 695-701. PMID 25491266 DOI: 10.1002/Adhm.201400648  0.522
2015 Appel EA, Larson BL, Luly KM, Kim JD, Langer R. Non-cell-adhesive substrates for printing of arrayed biomaterials. Advanced Healthcare Materials. 4: 501-5. PMID 25430948 DOI: 10.1002/Adhm.201400594  0.624
2015 Veiseh O, Tang BC, Whitehead KA, Anderson DG, Langer R. Managing diabetes with nanomedicine: challenges and opportunities. Nature Reviews. Drug Discovery. 14: 45-57. PMID 25430866 DOI: 10.1038/Nrd4477  0.738
2015 O'Shea TM, Aimetti AA, Kim E, Yesilyurt V, Langer R. Synthesis and characterization of a library of in-situ curing, nonswelling ethoxylated polyol thiol-ene hydrogels for tailorable macromolecule delivery. Advanced Materials (Deerfield Beach, Fla.). 27: 65-72. PMID 25381960 DOI: 10.1002/Adma.201403724  0.366
2015 Traverso G, Schoellhammer CM, Schroeder A, Maa R, Lauwers GY, Polat BE, Anderson DG, Blankschtein D, Langer R. Microneedles for drug delivery via the gastrointestinal tract. Journal of Pharmaceutical Sciences. 104: 362-7. PMID 25250829 DOI: 10.1002/Jps.24182  0.669
2015 Webber MJ, Khan OF, Sydlik SA, Tang BC, Langer R. A perspective on the clinical translation of scaffolds for tissue engineering. Annals of Biomedical Engineering. 43: 641-56. PMID 25201605 DOI: 10.1007/S10439-014-1104-7  0.686
2015 Webber MJ, Anderson DG, Langer R. Engineering synthetically modified insulin for glucose-responsive diabetes therapy Expert Review of Endocrinology and Metabolism. 10: 483-489. DOI: 10.1586/17446651.2015.1071187  0.706
2015 Saung MT, Sharei A, Adalsteinsson V, Liss A, Cho N, Kamath T, Ruiz C, Kirkpatrick J, Langer R, Love C, Jensen K. Abstract 5538A: Cell size-specific intracellular delivery Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-5538A  0.307
2015 Appel EA, Tibbitt MW, Webber MJ, Mattix BA, Veiseh O, Langer R. Self-assembled hydrogels utilizing polymer-nanoparticle interactions Nature Communications. 6. DOI: 10.1038/ncomms7295  0.746
2015 Appel EA, Tibbitt MW, Greer JM, Fenton OS, Kreuels K, Anderson DG, Langer R. Exploiting Electrostatic Interactions in Polymer-Nanoparticle Hydrogels Acs Macro Letters. 4: 848-852. DOI: 10.1021/Acsmacrolett.5B00416  0.703
2015 Schoellhammer C, Schroeder A, Maa R, Brugge WR, Lauwers GY, Anderson D, Blankschtein D, Langer R, Traverso G. Sa1251 Ultrasound-Mediated Gastrointestinal Drug Delivery for Ulcerative Colitis Gastroenterology. 148: S-269-S-270. DOI: 10.1016/S0016-5085(15)30891-X  0.656
2015 Patel AK, Tibbitt MW, Celiz AD, Davies MC, Langer R, Denning C, Alexander MR, Anderson DG. High throughput screening for discovery of materials that control stem cell fate Current Opinion in Solid State and Materials Science. DOI: 10.1016/J.Cossms.2016.02.002  0.529
2015 Wang Q, Cheng H, Peng H, Zhou H, Li PY, Langer R. Non-genetic engineering of cells for drug delivery and cell-based therapy Advanced Drug Delivery Reviews. DOI: 10.1016/j.addr.2014.12.003  0.333
2015 Webber MJ, Khan OF, Sydlik SA, Tang BC, Langer R. A Perspective on the Clinical Translation of Scaffolds for Tissue Engineering Annals of Biomedical Engineering. 43: 641-656. DOI: 10.1007/s10439-014-1104-7  0.644
2015 O'Shea TM, Webber MJ, Aimetti AA, Langer R. Covalent Incorporation of Trehalose within Hydrogels for Enhanced Long-Term Functional Stability and Controlled Release of Biomacromolecules Advanced Healthcare Materials. DOI: 10.1002/adhm.201500334  0.644
2014 Goldberg M, Manzi A, Aydin E, Singh G, Khoshkenar P, Birdi A, LaPorte B, Krauskopf A, Powell G, Chen J, Langer R. Development of a Nanoparticle-Embedded Chitosan Sponge for Topical and Local Administration of Chemotherapeutic Agents. Journal of Nanotechnology in Engineering and Medicine. 5: 0409051-4090511. PMID 26336575 DOI: 10.1115/1.4030899  0.321
2014 Dahlman JE, Kauffman KJ, Langer R, Anderson DG. Nanotechnology for in vivo targeted siRNA delivery. Advances in Genetics. 88: 37-69. PMID 25409603 DOI: 10.1016/B978-0-12-800148-6.00003-1  0.554
2014 Li L, Tong R, Chu H, Wang W, Langer R, Kohane DS. Aptamer photoregulation in vivo. Proceedings of the National Academy of Sciences of the United States of America. 111: 17099-103. PMID 25404344 DOI: 10.1073/Pnas.1420105111  0.658
2014 Laulicht B, Traverso G, Deshpande V, Langer R, Karp JM. Simple battery armor to protect against gastrointestinal injury from accidental ingestion. Proceedings of the National Academy of Sciences of the United States of America. 111: 16490-5. PMID 25368176 DOI: 10.1073/Pnas.1418423111  0.507
2014 Khan OF, Zaia EW, Yin H, Bogorad RL, Pelet JM, Webber MJ, Zhuang I, Dahlman JE, Langer R, Anderson DG. Ionizable amphiphilic dendrimer-based nanomaterials with alkyl-chain-substituted amines for tunable siRNA delivery to the liver endothelium in vivo. Angewandte Chemie (International Ed. in English). 53: 14397-401. PMID 25354018 DOI: 10.1002/Anie.201408221  0.758
2014 Celiz AD, Smith JG, Patel AK, Langer R, Anderson DG, Barrett DA, Young LE, Davies MC, Denning C, Alexander MR. Chemically diverse polymer microarrays and high throughput surface characterisation: a method for discovery of materials for stem cell culture†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4bm00054dClick here for additional data file. Biomaterials Science. 2: 1604-1611. PMID 25328672 DOI: 10.1039/C4Bm00054D  0.566
2014 Oberli MA, Schoellhammer CM, Langer R, Blankschtein D. Ultrasound-enhanced transdermal delivery: recent advances and future challenges. Therapeutic Delivery. 5: 843-57. PMID 25287389 DOI: 10.4155/Tde.14.32  0.551
2014 Zhu X, Radovic-Moreno AF, Wu J, Langer R, Shi J. Nanomedicine in the Management of Microbial Infection - Overview and Perspectives. Nano Today. 9: 478-498. PMID 25267927 DOI: 10.1016/J.Nantod.2014.06.003  0.433
2014 Platt RJ, Chen S, Zhou Y, Yim MJ, Swiech L, Kempton HR, Dahlman JE, Parnas O, Eisenhaure TM, Jovanovic M, Graham DB, Jhunjhunwala S, Heidenreich M, Xavier RJ, Langer R, et al. CRISPR-Cas9 knockin mice for genome editing and cancer modeling. Cell. 159: 440-55. PMID 25263330 DOI: 10.1016/J.Cell.2014.09.014  0.722
2014 Xue W, Dahlman JE, Tammela T, Khan OF, Sood S, Dave A, Cai W, Chirino LM, Yang GR, Bronson R, Crowley DG, Sahay G, Schroeder A, Langer R, Anderson DG, et al. Small RNA combination therapy for lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 111: E3553-61. PMID 25114235 DOI: 10.1073/Pnas.1412686111  0.775
2014 Mitragotri S, Burke PA, Langer R. Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies. Nature Reviews. Drug Discovery. 13: 655-72. PMID 25103255 DOI: 10.1038/Nrd4363  0.648
2014 Algahtani MS, Scurr DJ, Hook AL, Anderson DG, Langer RS, Burley JC, Alexander MR, Davies MC. High throughput screening for biomaterials discovery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 190: 115-26. PMID 24993427 DOI: 10.1016/J.Jconrel.2014.06.045  0.519
2014 Whitehead KA, Dorkin JR, Vegas AJ, Chang PH, Veiseh O, Matthews J, Fenton OS, Zhang Y, Olejnik KT, Yesilyurt V, Chen D, Barros S, Klebanov B, Novobrantseva T, Langer R, et al. Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity. Nature Communications. 5: 4277. PMID 24969323 DOI: 10.1038/Ncomms5277  0.792
2014 Barhoumi A, Wang W, Zurakowski D, Langer RS, Kohane DS. Photothermally targeted thermosensitive polymer-masked nanoparticles. Nano Letters. 14: 3697-701. PMID 24884872 DOI: 10.1021/Nl403733Z  0.675
2014 Celiz AD, Smith JG, Langer R, Anderson DG, Winkler DA, Barrett DA, Davies MC, Young LE, Denning C, Alexander MR. Materials for stem cell factories of the future. Nature Materials. 13: 570-9. PMID 24845996 DOI: 10.1038/Nmat3972  0.485
2014 Lim JM, Swami A, Gilson LM, Chopra S, Choi S, Wu J, Langer R, Karnik R, Farokhzad OC. Ultra-high throughput synthesis of nanoparticles with homogeneous size distribution using a coaxial turbulent jet mixer. Acs Nano. 8: 6056-65. PMID 24824296 DOI: 10.1021/Nn501371N  0.692
2014 Dahlman JE, Barnes C, Khan OF, Thiriot A, Jhunjunwala S, Shaw TE, Xing Y, Sager HB, Sahay G, Speciner L, Bader A, Bogorad RL, Yin H, Racie T, Dong Y, ... ... Langer R, et al. In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight. Nature Nanotechnology. 9: 648-55. PMID 24813696 DOI: 10.1038/Nnano.2014.84  0.787
2014 Cima MJ, Lee H, Daniel K, Tanenbaum LM, Mantzavinou A, Spencer KC, Ong Q, Sy JC, Santini J, Schoellhammer CM, Blankschtein D, Langer RS. Single compartment drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 190: 157-71. PMID 24798478 DOI: 10.1016/J.Jconrel.2014.04.049  0.554
2014 Dong Y, Eltoukhy AA, Alabi CA, Khan OF, Veiseh O, Dorkin JR, Sirirungruang S, Yin H, Tang BC, Pelet JM, Chen D, Gu Z, Xue Y, Langer R, Anderson DG. Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo. Advanced Healthcare Materials. 3: 1392-7. PMID 24623658 DOI: 10.1002/Adhm.201400054  0.752
2014 Ilyinskii PO, Roy CJ, O'Neil CP, Browning EA, Pittet LA, Altreuter DH, Alexis F, Tonti E, Shi J, Basto PA, Iannacone M, Radovic-Moreno AF, Langer RS, Farokhzad OC, von Andrian UH, et al. Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release. Vaccine. 32: 2882-95. PMID 24593999 DOI: 10.1016/J.Vaccine.2014.02.027  0.548
2014 Chan KM, Li RH, Chapman JW, Trac EM, Kobler JB, Zeitels SM, Langer R, Karajanagi SS. Functionalizable hydrogel microparticles of tunable size and stiffness for soft-tissue filler applications. Acta Biomaterialia. 10: 2563-73. PMID 24561708 DOI: 10.1016/J.Actbio.2014.02.021  0.342
2014 Dong Y, Love KT, Dorkin JR, Sirirungruang S, Zhang Y, Chen D, Bogorad RL, Yin H, Chen Y, Vegas AJ, Alabi CA, Sahay G, Olejnik KT, Wang W, Schroeder A, ... ... Langer R, et al. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates. Proceedings of the National Academy of Sciences of the United States of America. 111: 3955-60. PMID 24516150 DOI: 10.1073/Pnas.1322937111  0.774
2014 Hook AL, Chang CY, Scurr DJ, Langer R, Anderson DG, Williams P, Davies MC, Alexander MR. Thermally switchable polymers achieve controlled Escherichia coli detachment. Advanced Healthcare Materials. 3: 1020-5. PMID 24497458 DOI: 10.1002/Adhm.201300518  0.536
2014 Sharei A, Poceviciute R, Jackson EL, Cho N, Mao S, Hartoularos GC, Jang DY, Jhunjhunwala S, Eyerman A, Schoettle T, Langer R, Jensen KF. Plasma membrane recovery kinetics of a microfluidic intracellular delivery platform. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 470-5. PMID 24496115 DOI: 10.1039/C3Ib40215K  0.663
2014 Timko BP, Arruebo M, Shankarappa SA, McAlvin JB, Okonkwo OS, Mizrahi B, Stefanescu CF, Gomez L, Zhu J, Zhu A, Santamaria J, Langer R, Kohane DS. Near-infrared-actuated devices for remotely controlled drug delivery. Proceedings of the National Academy of Sciences of the United States of America. 111: 1349-54. PMID 24474759 DOI: 10.1073/Pnas.1322651111  0.791
2014 Lang N, Pereira MJ, Lee Y, Friehs I, Vasilyev NV, Feins EN, Ablasser K, O'Cearbhaill ED, Xu C, Fabozzo A, Padera R, Wasserman S, Freudenthal F, Ferreira LS, Langer R, et al. A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects. Science Translational Medicine. 6: 218ra6. PMID 24401941 DOI: 10.1126/Scitranslmed.3006557  0.76
2014 Kim Y, Lobatto ME, Kawahara T, Lee Chung B, Mieszawska AJ, Sanchez-Gaytan BL, Fay F, Senders ML, Calcagno C, Becraft J, Tun Saung M, Gordon RE, Stroes ES, Ma M, Farokhzad OC, ... ... Langer R, et al. Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 111: 1078-83. PMID 24395808 DOI: 10.1073/Pnas.1322725111  0.558
2014 Schoellhammer CM, Blankschtein D, Langer R. Skin permeabilization for transdermal drug delivery: recent advances and future prospects. Expert Opinion On Drug Delivery. 11: 393-407. PMID 24392787 DOI: 10.1517/17425247.2014.875528  0.537
2014 Yin X, Farin HF, van Es JH, Clevers H, Langer R, Karp JM. Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny. Nature Methods. 11: 106-12. PMID 24292484 DOI: 10.1038/Nmeth.2737  0.528
2014 Guo L, Ma M, Zhang N, Langer R, Anderson DG. Stretchable polymeric multielectrode array for conformal neural interfacing. Advanced Materials (Deerfield Beach, Fla.). 26: 1427-33. PMID 24150828 DOI: 10.1002/Adma.201304140  0.626
2014 Pereira MJ, Sundback CA, Lang N, Cho WK, Pomerantseva I, Ouyang B, Tao SL, McHugh K, Mwizerwa O, Vemula PK, Mochel MC, Carter DJ, Borenstein JT, Langer R, Ferreira LS, et al. Combined surface micropatterning and reactive chemistry maximizes tissue adhesion with minimal inflammation. Advanced Healthcare Materials. 3: 565-71. PMID 24106240 DOI: 10.1002/Adhm.201300264  0.549
2014 Lim JM, Bertrand N, Valencia PM, Rhee M, Langer R, Jon S, Farokhzad OC, Karnik R. Parallel microfluidic synthesis of size-tunable polymeric nanoparticles using 3D flow focusing towards in vivo study Nanomedicine: Nanotechnology, Biology, and Medicine. 10: 401-409. PMID 23969105 DOI: 10.1016/J.Nano.2013.08.003  0.692
2014 Ligorio M, Indolfi L, Ting DT, Xega K, Aceto N, Bersani F, Ferrone CR, Haber DA, Langer R, Edelman ER, Clark JW. Abstract 4584: A novel drug-eluting platform for localized treatment of pancreatic cancer Cancer Research. 74: 4584-4584. DOI: 10.1158/1538-7445.Am2014-4584  0.604
2014 Lee JH, Traverso G, Schoellhammer CM, Blankschtein D, Langer R, Thomenius KE, Boning DS, Anthony BW. Towards wireless capsule endoscopic ultrasound (WCEU) Ieee International Ultrasonics Symposium, Ius. 734-737. DOI: 10.1109/ULTSYM.2014.0181  0.411
2014 Hook AL, Chang C, Yang J, Luckett J, Cockayne A, Atkinson S, Mei Y, Bayston R, Irvine DJ, Langer R, Anderson DG, Williams P, Davies MC, Alexander MR. Erratum: Corrigendum: Combinatorial discovery of polymers resistant to bacterial attachment Nature Biotechnology. 32: 592-592. DOI: 10.1038/Nbt0614-592C  0.501
2014 Guo L, Ma M, Zhang N, Langer R, Anderson DG. Conducting Polymers: Stretchable Polymeric Multielectrode Array for Conformal Neural Interfacing (Adv. Mater. 9/2014) Advanced Materials. 26: 1310-1310. DOI: 10.1002/Adma.201470055  0.634
2014 Epa VC, Hook AL, Chang C, Yang J, Langer R, Anderson DG, Williams P, Davies MC, Alexander MR, Winkler DA. Modelling and prediction of bacterial attachment to polymers Advanced Functional Materials. 24: 2085-2093. DOI: 10.1002/Adfm.201302877  0.486
2014 Tekin H, Khademhosseini A, Langer RS. Award submission: Dynamic microstructures for controlling spatial organization of biological entities and materials within defined geometries Nanoscale Science and Engineering Forum 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 157-158.  0.442
2013 Hook AL, Scurr DJ, Burley JC, Langer R, Anderson DG, Davies MC, Alexander MR. Analysis and prediction of defects in UV photo-initiated polymer microarrays. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 1: 1035-1043. PMID 25798286 DOI: 10.1039/C2Tb00379A  0.547
2013 Sharei A, Cho N, Mao S, Jackson E, Poceviciute R, Adamo A, Zoldan J, Langer R, Jensen KF. Cell squeezing as a robust, microfluidic intracellular delivery platform. Journal of Visualized Experiments : Jove. e50980. PMID 24300077 DOI: 10.3791/50980  0.351
2013 Pridgen EM, Alexis F, Kuo TT, Levy-Nissenbaum E, Karnik R, Blumberg RS, Langer R, Farokhzad OC. Transepithelial transport of Fc-targeted nanoparticles by the neonatal fc receptor for oral delivery. Science Translational Medicine. 5: 213ra167. PMID 24285486 DOI: 10.1126/Scitranslmed.3007049  0.697
2013 Valencia PM, Pridgen EM, Rhee M, Langer R, Farokhzad OC, Karnik R. Microfluidic platform for combinatorial synthesis and optimization of targeted nanoparticles for cancer therapy. Acs Nano. 7: 10671-80. PMID 24215426 DOI: 10.1021/Nn403370E  0.694
2013 Zugates GT, Anderson DG, Langer R. High-throughput methods for screening polymeric transfection reagents. Cold Spring Harbor Protocols. 2013. PMID 24184768 DOI: 10.1101/Pdb.Prot078634  0.56
2013 Xu X, Xie K, Zhang XQ, Pridgen EM, Park GY, Cui DS, Shi J, Wu J, Kantoff PW, Lippard SJ, Langer R, Walker GC, Farokhzad OC. Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug. Proceedings of the National Academy of Sciences of the United States of America. 110: 18638-43. PMID 24167294 DOI: 10.1073/Pnas.1303958110  0.541
2013 Saigal R, Cimetta E, Tandon N, Zhou J, Langer R, Young M, Vunjak-Novakovic G, Redenti S. Electrical stimulation via a biocompatible conductive polymer directs retinal progenitor cell differentiation. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2013: 1627-31. PMID 24110015 DOI: 10.1109/EMBC.2013.6609828  0.625
2013 Kim Y, Fay F, Cormode DP, Sanchez-Gaytan BL, Tang J, Hennessy EJ, Ma M, Moore K, Farokhzad OC, Fisher EA, Mulder WJ, Langer R, Fayad ZA. Single step reconstitution of multifunctional high-density lipoprotein-derived nanomaterials using microfluidics. Acs Nano. 7: 9975-83. PMID 24079940 DOI: 10.1021/Nn4039063  0.538
2013 Gabriel D, Monteiro IP, Huang D, Langer R, Kohane DS. A photo-triggered layered surface coating producing reactive oxygen species. Biomaterials. 34: 9763-9. PMID 24074838 DOI: 10.1016/J.Biomaterials.2013.09.021  0.65
2013 Karagiannis ED, Urbanska AM, Sahay G, Pelet JM, Jhunjhunwala S, Langer R, Anderson DG. Rational design of a biomimetic cell penetrating peptide library. Acs Nano. 7: 8616-26. PMID 24047542 DOI: 10.1021/Nn4027382  0.783
2013 Mieszawska AJ, Kim Y, Gianella A, van Rooy I, Priem B, Labarre MP, Ozcan C, Cormode DP, Petrov A, Langer R, Farokhzad OC, Fayad ZA, Mulder WJ. Synthesis of polymer-lipid nanoparticles for image-guided delivery of dual modality therapy. Bioconjugate Chemistry. 24: 1429-34. PMID 23957728 DOI: 10.1021/Bc400166J  0.563
2013 Chertok B, Webber MJ, Succi MD, Langer R. Drug delivery interfaces in the 21st century: from science fiction ideas to viable technologies. Molecular Pharmaceutics. 10: 3531-43. PMID 23915375 DOI: 10.1021/Mp4003283  0.796
2013 Lim DK, Barhoumi A, Wylie RG, Reznor G, Langer RS, Kohane DS. Enhanced photothermal effect of plasmonic nanoparticles coated with reduced graphene oxide. Nano Letters. 13: 4075-9. PMID 23899267 DOI: 10.1021/Nl4014315  0.63
2013 Alabi CA, Love KT, Sahay G, Yin H, Luly KM, Langer R, Anderson DG. Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery. Proceedings of the National Academy of Sciences of the United States of America. 110: 12881-6. PMID 23882076 DOI: 10.1073/Pnas.1306529110  0.789
2013 Gianella A, Mieszawska AJ, Hoeben FJM, Janssen HM, Jarzyna PA, Cormode DP, Costa KD, Rao S, Farokhzad OC, Langer R, Fayad ZA, Mulder WJM. Synthesis and in vitro evaluation of a multifunctional and surface-switchable nanoemulsion platform Chemical Communications. 49: 9392-9394. PMID 23877789 DOI: 10.1039/C3Cc43618G  0.533
2013 Sahay G, Querbes W, Alabi C, Eltoukhy A, Sarkar S, Zurenko C, Karagiannis E, Love K, Chen D, Zoncu R, Buganim Y, Schroeder A, Langer R, Anderson DG. Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling. Nature Biotechnology. 31: 653-8. PMID 23792629 DOI: 10.1038/Nbt.2614  0.794
2013 Langer R. Biomaterials and biotechnology: From the discovery of the first angiogenesis inhibitors to the development of controlled drug delivery systems and the foundation of tissue engineering Journal of Biomedical Materials Research - Part A. 101: 2449-2455. PMID 23723136 DOI: 10.1002/Jbm.A.34811  0.326
2013 Gu M, Vegas AJ, Anderson DG, Langer RS, Kilduff JE, Belfort G. Combinatorial synthesis with high throughput discovery of protein-resistant membrane surfaces. Biomaterials. 34: 6133-8. PMID 23706542 DOI: 10.1016/J.Biomaterials.2013.04.051  0.767
2013 Johnstone TC, Kulak N, Pridgen EM, Farokhzad OC, Langer R, Lippard SJ. Nanoparticle encapsulation of mitaplatin and the effect thereof on in vivo properties. Acs Nano. 7: 5675-83. PMID 23697579 DOI: 10.1021/Nn401905G  0.562
2013 Mizrahi B, Shankarappa SA, Hickey JM, Dohlman JC, Timko BP, Whitehead KA, Lee JJ, Langer R, Anderson DG, Kohane DS. A Stiff Injectable Biodegradable Elastomer. Advanced Functional Materials. 23: 1527-1533. PMID 23667350 DOI: 10.1002/Adfm.201202433  0.777
2013 Dang TT, Thai AV, Cohen J, Slosberg JE, Siniakowicz K, Doloff JC, Ma M, Hollister-Lock J, Tang KM, Gu Z, Cheng H, Weir GC, Langer R, Anderson DG. Enhanced function of immuno-isolated islets in diabetes therapy by co-encapsulation with an anti-inflammatory drug. Biomaterials. 34: 5792-801. PMID 23660251 DOI: 10.1016/J.Biomaterials.2013.04.016  0.765
2013 Gu Z, Aimetti AA, Wang Q, Dang TT, Zhang Y, Veiseh O, Cheng H, Langer RS, Anderson DG. Injectable nano-network for glucose-mediated insulin delivery. Acs Nano. 7: 4194-201. PMID 23638642 DOI: 10.1021/Nn400630X  0.7
2013 Kamaly N, Fredman G, Subramanian M, Gadde S, Pesic A, Cheung L, Fayad ZA, Langer R, Tabas I, Farokhzad OC. Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles. Proceedings of the National Academy of Sciences of the United States of America. 110: 6506-11. PMID 23533277 DOI: 10.1073/Pnas.1303377110  0.548
2013 Wang J, Boutin KG, Abdulhadi O, Personnat LD, Shazly T, Langer R, Channick CL, Borenstein JT. Fully biodegradable airway stents using amino alcohol-based poly(ester amide) elastomers. Advanced Healthcare Materials. 2: 1329-36. PMID 23526787 DOI: 10.1002/Adhm.201200348  0.703
2013 Hook AL, Scurr DJ, Anderson DG, Langer R, Williams P, Davies M, Alexander M. High throughput discovery of thermo-responsive materials using water contact angle measurements and time-of-flight secondary ion mass spectrometry. Surface and Interface Analysis : Sia. 45: 181-184. PMID 23450147 DOI: 10.1002/Sia.4910  0.534
2013 Haq R, Yokoyama S, Hawryluk EB, Jönsson GB, Frederick DT, McHenry K, Porter D, Tran TN, Love KT, Langer R, Anderson DG, Garraway LA, Duncan LM, Morton DL, Hoon DS, et al. BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition. Proceedings of the National Academy of Sciences of the United States of America. 110: 4321-6. PMID 23447565 DOI: 10.1073/Pnas.1205575110  0.522
2013 Hook AL, Chang CY, Yang J, Atkinson S, Langer R, Anderson DG, Davies MC, Williams P, Alexander MR. Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays. Advanced Materials (Deerfield Beach, Fla.). 25: 2542-7. PMID 23417823 DOI: 10.1002/Adma.201204936  0.529
2013 Jiang S, Eltoukhy AA, Love KT, Langer R, Anderson DG. Lipidoid-coated iron oxide nanoparticles for efficient DNA and siRNA delivery. Nano Letters. 13: 1059-64. PMID 23394319 DOI: 10.1021/Nl304287A  0.555
2013 Sharei A, Zoldan J, Adamo A, Sim WY, Cho N, Jackson E, Mao S, Schneider S, Han MJ, Lytton-Jean A, Basto PA, Jhunjhunwala S, Lee J, Heller DA, Kang JW, ... ... Langer R, et al. A vector-free microfluidic platform for intracellular delivery. Proceedings of the National Academy of Sciences of the United States of America. 110: 2082-7. PMID 23341631 DOI: 10.1073/Pnas.1218705110  0.798
2013 Ma M, Guo L, Anderson DG, Langer R. Bio-inspired polymer composite actuator and generator driven by water gradients. Science (New York, N.Y.). 339: 186-9. PMID 23307738 DOI: 10.1126/Science.1230262  0.632
2013 Eltoukhy AA, Chen D, Alabi CA, Langer R, Anderson DG. Degradable terpolymers with alkyl side chains demonstrate enhanced gene delivery potency and nanoparticle stability. Advanced Materials (Deerfield Beach, Fla.). 25: 1487-93. PMID 23293063 DOI: 10.1002/Adma.201204346  0.741
2013 Heller DA, Levi Y, Pelet JM, Doloff JC, Wallas J, Pratt GW, Jiang S, Sahay G, Schroeder A, Schroeder JE, Chyan Y, Zurenko C, Querbes W, Manzano M, Kohane DS, ... Langer R, et al. Modular 'click-in-emulsion' bone-targeted nanogels. Advanced Materials (Deerfield Beach, Fla.). 25: 1449-54. PMID 23280931 DOI: 10.1002/Adma.201202881  0.758
2013 Pereira MJ, Ouyang B, Sundback CA, Lang N, Friehs I, Mureli S, Pomerantseva I, McFadden J, Mochel MC, Mwizerwa O, Del Nido P, Sarkar D, Masiakos PT, Langer R, Ferreira LS, et al. A highly tunable biocompatible and multifunctional biodegradable elastomer. Advanced Materials (Deerfield Beach, Fla.). 25: 1209-15. PMID 23239051 DOI: 10.1002/Adma.201203824  0.568
2013 Hashimoto M, Langer R, Kohane DS. Benchtop fabrication of microfluidic systems based on curable polymers with improved solvent compatibility. Lab On a Chip. 13: 252-9. PMID 23192674 DOI: 10.1039/C2Lc40888K  0.75
2013 Neal RA, Jean A, Park H, Wu PB, Hsiao J, Engelmayr GC, Langer R, Freed LE. Three-dimensional elastomeric scaffolds designed with cardiac-mimetic structural and mechanical features Tissue Engineering - Part A. 19: 793-807. PMID 23190320 DOI: 10.1089/Ten.Tea.2012.0330  0.307
2013 Khoo X, Simons EJ, Chiang HH, Hickey JM, Sabharwal V, Pelton SI, Rosowski JJ, Langer R, Kohane DS. Formulations for trans-tympanic antibiotic delivery. Biomaterials. 34: 1281-8. PMID 23146430 DOI: 10.1016/J.Biomaterials.2012.10.025  0.799
2013 Valencia PM, Pridgen EM, Perea B, Gadde S, Sweeney C, Kantoff PW, Bander NH, Lippard SJ, Langer R, Karnik R, Farokhzad OC. Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles. Nanomedicine (London, England). 8: 687-98. PMID 23075285 DOI: 10.2217/Nnm.12.134  0.703
2013 Alabi CA, Sahay G, Langer R, Anderson DG. Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 224-30. PMID 23014672 DOI: 10.1039/C2Ib20155K  0.778
2013 Bonner DK, Zhao X, Buss H, Langer R, Hammond PT. Crosslinked linear polyethylenimine enhances delivery of DNA to the cytoplasm. Journal of Controlled Release : Official Journal of the Controlled Release Society. 167: 101-7. PMID 22995755 DOI: 10.1016/J.Jconrel.2012.09.004  0.62
2013 Xu X, Zhang X, Xie K, Pridgen E, Langer R, Walker G, Farokhzad O. Abstract 5616: Enhancing tumor cell response to chemotherapy by simultaneous delivery of siRNA and cisplatin using polymeric nanoparticles. Cancer Research. 73: 5616-5616. DOI: 10.1158/1538-7445.Am2013-5616  0.307
2013 Shi J, Xu Y, Xu X, Votruba A, Zhu X, Pridgen E, Xiao Z, Langer R, Zetter BR, Farokhzad OC. Abstract 4529: Self-assembled lipid-polymer hybrid nanoparticles for the sustained delivery of siRNA and the treatment of drug-resistant cancers. Cancer Research. 73: 4529-4529. DOI: 10.1158/1538-7445.Am2013-4529  0.344
2013 Karnik R, Langer RS. Rebuilding OurselvesUshering in an Age of Synthetic Organs and Targeted Medicine Mechanical Engineering. 135: 30-35. DOI: 10.1115/1.2013-Feb-1  0.56
2013 Lang N, Pereira MN, Friehs I, Vasilyev NV, Feins EN, Fabozzo A, Lee Y, Langer R, Karp JM, Del Nido PJ. The use of a biocompatible photo-curable adhesive for intra- and extracardiac applications in acquired and congenital heart disease European Heart Journal. 34: P2153-P2153. DOI: 10.1093/Eurheartj/Eht308.P2153  0.704
2013 Levenberg S, Khademhosseini A, Langer R. Embryonic Stem Cells in Tissue Engineering Handbook of Stem Cells. 1: 427-437. DOI: 10.1016/B978-0-12-385942-6.00037-8  0.473
2013 Celiz AD, Hook AL, Scurr DJ, Anderson DG, Langer R, Davies MC, Alexander MR. ToF-SIMS imaging of a polymer microarray prepared using ink-jet printing of acrylate monomers Surface and Interface Analysis. 45: 202-205. DOI: 10.1002/Sia.5042  0.553
2012 Epa VC, Yang J, Mei Y, Hook AL, Langer R, Anderson DG, Davies MC, Alexander MR, Winkler DA. Modelling human embryoid body cell adhesion to a combinatorial library of polymer surfaces. Journal of Materials Chemistry. 22: 20902-20906. PMID 24092955 DOI: 10.1039/C2Jm34782B  0.572
2012 Siegwart DJ, Leiendecker M, Langer R, Anderson DG. Automated ARGET ATRP Accelerates Catalyst Optimization for the Synthesis of Thiol-Functionalized Polymers. Macromolecules. 45: 1254-1261. PMID 23599541 DOI: 10.1021/Ma3000219  0.538
2012 Kang SM, Hwang NS, Yeom J, Park SY, Messersmith PB, Choi IS, Langer R, Anderson DG, Lee H. One-Step Multipurpose Surface Functionalization by Adhesive Catecholamine. Advanced Functional Materials. 22: 2949-2955. PMID 23580891 DOI: 10.1002/Adfm.201200177  0.605
2012 Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, ... ... Langer R, et al. Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells. Molecular Therapy. Nucleic Acids. 1: e4. PMID 23344621 DOI: 10.1038/Mtna.2011.3  0.564
2012 Kastrup CJ, Nahrendorf M, Figueiredo JL, Lee H, Kambhampati S, Lee T, Cho SW, Gorbatov R, Iwamoto Y, Dang TT, Dutta P, Yeon JH, Cheng H, Pritchard CD, Vegas AJ, ... ... Langer R, et al. Painting blood vessels and atherosclerotic plaques with an adhesive drug depot. Proceedings of the National Academy of Sciences of the United States of America. 109: 21444-9. PMID 23236189 DOI: 10.1073/Pnas.1217972110  0.793
2012 Cho WK, Ankrum JA, Guo D, Chester SA, Yang SY, Kashyap A, Campbell GA, Wood RJ, Rijal RK, Karnik R, Langer R, Karp JM. Microstructured barbs on the North American porcupine quill enable easy tissue penetration and difficult removal. Proceedings of the National Academy of Sciences of the United States of America. 109: 21289-94. PMID 23236138 DOI: 10.1073/Pnas.1216441109  0.686
2012 Bratlie KM, York RL, Invernale MA, Langer R, Anderson DG. Materials for diabetes therapeutics. Advanced Healthcare Materials. 1: 267-84. PMID 23184741 DOI: 10.1002/Adhm.201200037  0.754
2012 Lee J, Sharei A, Sim WY, Adamo A, Langer R, Jensen KF, Bawendi MG. Nonendocytic delivery of functional engineered nanoparticles into the cytoplasm of live cells using a novel, high-throughput microfluidic device. Nano Letters. 12: 6322-7. PMID 23145796 DOI: 10.1021/Nl303421H  0.33
2012 Laulicht B, Langer R, Karp JM. Quick-release medical tape. Proceedings of the National Academy of Sciences of the United States of America. 109: 18803-8. PMID 23112196 DOI: 10.1073/Pnas.1216071109  0.511
2012 Shankarappa SA, Tsui JH, Kim KN, Reznor G, Dohlman JC, Langer R, Kohane DS. Prolonged nerve blockade delays the onset of neuropathic pain. Proceedings of the National Academy of Sciences of the United States of America. 109: 17555-60. PMID 23045676 DOI: 10.1073/Pnas.1214634109  0.761
2012 Valencia PM, Farokhzad OC, Karnik R, Langer R. Microfluidic technologies for accelerating the clinical translation of nanoparticles. Nature Nanotechnology. 7: 623-9. PMID 23042546 DOI: 10.1038/Nnano.2012.168  0.699
2012 Smith RS, Zhang Z, Bouchard M, Li J, Lapp HS, Brotske GR, Lucchino DL, Weaver D, Roth LA, Coury A, Biggerstaff J, Sukavaneshvar S, Langer R, Loose C. Vascular catheters with a nonleaching poly-sulfobetaine surface modification reduce thrombus formation and microbial attachment. Science Translational Medicine. 4: 153ra132. PMID 23019657 DOI: 10.1126/Scitranslmed.3004120  0.309
2012 Tekin H, Sanchez JG, Landeros C, Dubbin K, Langer R, Khademhosseini A. Controlling spatial organization of multiple cell types in defined 3D geometries. Advanced Materials (Deerfield Beach, Fla.). 24: 5543-7, 5542. PMID 22941804 DOI: 10.1002/Adma.201201805  0.532
2012 Schoellhammer CM, Polat BE, Mendenhall J, Maa R, Jones B, Hart DP, Langer R, Blankschtein D. Rapid skin permeabilization by the simultaneous application of dual-frequency, high-intensity ultrasound. Journal of Controlled Release : Official Journal of the Controlled Release Society. 163: 154-60. PMID 22940128 DOI: 10.1016/J.Jconrel.2012.08.019  0.507
2012 Cohen-Karni T, Jeong KJ, Tsui JH, Reznor G, Mustata M, Wanunu M, Graham A, Marks C, Bell DC, Langer R, Kohane DS. Nanocomposite gold-silk nanofibers. Nano Letters. 12: 5403-6. PMID 22928701 DOI: 10.1021/Nl302810C  0.674
2012 Tian B, Liu J, Dvir T, Jin L, Tsui JH, Qing Q, Suo Z, Langer R, Kohane DS, Lieber CM. Macroporous nanowire nanoelectronic scaffolds for synthetic tissues. Nature Materials. 11: 986-94. PMID 22922448 DOI: 10.1038/Nmat3404  0.783
2012 Vacanti NM, Cheng H, Hill PS, Guerreiro JD, Dang TT, Ma M, Watson S, Hwang NS, Langer R, Anderson DG. Localized delivery of dexamethasone from electrospun fibers reduces the foreign body response. Biomacromolecules. 13: 3031-8. PMID 22920794 DOI: 10.1021/Bm300520U  0.568
2012 Hook AL, Chang CY, Yang J, Luckett J, Cockayne A, Atkinson S, Mei Y, Bayston R, Irvine DJ, Langer R, Anderson DG, Williams P, Davies MC, Alexander MR. Combinatorial discovery of polymers resistant to bacterial attachment. Nature Biotechnology. 30: 868-75. PMID 22885723 DOI: 10.1038/Nbt.2316  0.551
2012 Cohen-Karni T, Langer R, Kohane DS. The smartest materials: the future of nanoelectronics in medicine. Acs Nano. 6: 6541-5. PMID 22850578 DOI: 10.1021/Nn302915S  0.669
2012 Kim Y, Lee Chung B, Ma M, Mulder WJ, Fayad ZA, Farokhzad OC, Langer R. Mass production and size control of lipid-polymer hybrid nanoparticles through controlled microvortices. Nano Letters. 12: 3587-91. PMID 22716029 DOI: 10.1021/Nl301253V  0.555
2012 Alabi CA, Love KT, Sahay G, Stutzman T, Young WT, Langer R, Anderson DG. FRET-labeled siRNA probes for tracking assembly and disassembly of siRNA nanocomplexes. Acs Nano. 6: 6133-41. PMID 22693946 DOI: 10.1021/Nn3013838  0.784
2012 Lee H, Lytton-Jean AK, Chen Y, Love KT, Park AI, Karagiannis ED, Sehgal A, Querbes W, Zurenko CS, Jayaraman M, Peng CG, Charisse K, Borodovsky A, Manoharan M, Donahoe JS, ... ... Langer R, et al. Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery. Nature Nanotechnology. 7: 389-93. PMID 22659608 DOI: 10.1038/Nnano.2012.73  0.575
2012 Masi BC, Tyler BM, Bow H, Wicks RT, Xue Y, Brem H, Langer R, Cima MJ. Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model. Biomaterials. 33: 5768-75. PMID 22591609 DOI: 10.1016/J.Biomaterials.2012.04.048  0.352
2012 Li J, Song JS, Bell RJ, Tran TN, Haq R, Liu H, Love KT, Langer R, Anderson DG, Larue L, Fisher DE. YY1 regulates melanocyte development and function by cooperating with MITF. Plos Genetics. 8: e1002688. PMID 22570637 DOI: 10.1371/Journal.Pgen.1002688  0.504
2012 Fisher OZ, Larson BL, Hill PS, Graupner D, Nguyen-Kim MT, Kehr NS, De Cola L, Langer R, Anderson DG. Melanin-like hydrogels derived from gallic macromers. Advanced Materials (Deerfield Beach, Fla.). 24: 3032-6. PMID 22566290 DOI: 10.1002/Adma.201104437  0.526
2012 Mieszawska AJ, Gianella A, Cormode DP, Zhao Y, Meijerink A, Langer R, Farokhzad OC, Fayad ZA, Mulder WJ. Engineering of lipid-coated PLGA nanoparticles with a tunable payload of diagnostically active nanocrystals for medical imaging. Chemical Communications (Cambridge, England). 48: 5835-7. PMID 22555311 DOI: 10.1039/C2Cc32149A  0.556
2012 Cheng H, Byrska-Bishop M, Zhang CT, Kastrup CJ, Hwang NS, Tai AK, Lee WW, Xu X, Nahrendorf M, Langer R, Anderson DG. Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell-selectin interaction kinetics. Biomaterials. 33: 5004-12. PMID 22494889 DOI: 10.1016/J.Biomaterials.2012.03.065  0.55
2012 Hrkach J, Von Hoff D, Mukkaram Ali M, Andrianova E, Auer J, Campbell T, De Witt D, Figa M, Figueiredo M, Horhota A, Low S, McDonnell K, Peeke E, Retnarajan B, Sabnis A, ... ... Langer R, et al. Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile. Science Translational Medicine. 4: 128ra39. PMID 22491949 DOI: 10.1126/Scitranslmed.3003651  0.543
2012 Urbanska AM, Karagiannis ED, Guajardo G, Langer RS, Anderson DG. Therapeutic effect of orally administered microencapsulated oxaliplatin for colorectal cancer. Biomaterials. 33: 4752-61. PMID 22472433 DOI: 10.1016/J.Biomaterials.2012.03.023  0.538
2012 Radovic-Moreno AF, Lu TK, Puscasu VA, Yoon CJ, Langer R, Farokhzad OC. Surface charge-switching polymeric nanoparticles for bacterial cell wall-targeted delivery of antibiotics. Acs Nano. 6: 4279-87. PMID 22471841 DOI: 10.1021/Nn3008383  0.553
2012 Stevenson CL, Santini JT, Langer R. Reservoir-based drug delivery systems utilizing microtechnology. Advanced Drug Delivery Reviews. 64: 1590-602. PMID 22465783 DOI: 10.1016/J.Addr.2012.02.005  0.344
2012 Cho SW, Yang F, Son SM, Park HJ, Green JJ, Bogatyrev S, Mei Y, Park S, Langer R, Anderson DG. Therapeutic angiogenesis using genetically engineered human endothelial cells. Journal of Controlled Release : Official Journal of the Controlled Release Society. 160: 515-24. PMID 22450331 DOI: 10.1016/J.Jconrel.2012.03.006  0.555
2012 Schroeder A, Goldberg MS, Kastrup C, Wang Y, Jiang S, Joseph BJ, Levins CG, Kannan ST, Langer R, Anderson DG. Remotely activated protein-producing nanoparticles. Nano Letters. 12: 2685-9. PMID 22432731 DOI: 10.1021/Nl2036047  0.548
2012 Nguyen DN, Mahon KP, Chikh G, Kim P, Chung H, Vicari AP, Love KT, Goldberg M, Chen S, Krieg AM, Chen J, Langer R, Anderson DG. Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery. Proceedings of the National Academy of Sciences of the United States of America. 109: E797-803. PMID 22421433 DOI: 10.1073/Pnas.1121423109  0.549
2012 Tong R, Hemmati HD, Langer R, Kohane DS. Photoswitchable nanoparticles for triggered tissue penetration and drug delivery. Journal of the American Chemical Society. 134: 8848-55. PMID 22385538 DOI: 10.1021/Ja211888A  0.679
2012 Farra R, Sheppard NF, McCabe L, Neer RM, Anderson JM, Santini JT, Cima MJ, Langer R. First-in-human testing of a wirelessly controlled drug delivery microchip. Science Translational Medicine. 4: 122ra21. PMID 22344516 DOI: 10.1126/Scitranslmed.3003276  0.33
2012 Eltoukhy AA, Siegwart DJ, Alabi CA, Rajan JS, Langer R, Anderson DG. Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity. Biomaterials. 33: 3594-603. PMID 22341939 DOI: 10.1016/J.Biomaterials.2012.01.046  0.75
2012 Shichor I, Shomron N, Lawlor MW, Bae SA, Zoldan J, Langer R, Kohane DS. Toxicogenomic analysis of a sustained release local anesthetic delivery system. Biomaterials. 33: 3586-93. PMID 22341215 DOI: 10.1016/J.Biomaterials.2012.01.043  0.644
2012 Hook AL, Chang CY, Yang J, Scurr DJ, Langer R, Anderson DG, Atkinson S, Williams P, Davies MC, Alexander MR. Polymer microarrays for high throughput discovery of biomaterials. Journal of Visualized Experiments : Jove. e3636. PMID 22314927 DOI: 10.3791/3636  0.564
2012 Xiao Z, Levy-Nissenbaum E, Alexis F, Lupták A, Teply BA, Chan JM, Shi J, Digga E, Cheng J, Langer R, Farokhzad OC. Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection. Acs Nano. 6: 696-704. PMID 22214176 DOI: 10.1021/Nn204165V  0.548
2012 Salvador-Morales C, Valencia PM, Thakkar AB, Swanson EW, Langer R. Recent developments in multifunctional hybrid nanoparticles: opportunities and challenges in cancer therapy. Frontiers in Bioscience (Elite Edition). 4: 529-45. PMID 22201893 DOI: 10.2741/398  0.316
2012 Schroeder A, Heller DA, Winslow MM, Dahlman JE, Pratt GW, Langer R, Jacks T, Anderson DG. Treating metastatic cancer with nanotechnology. Nature Reviews. Cancer. 12: 39-50. PMID 22193407 DOI: 10.1038/Nrc3180  0.659
2012 Sun S, Wang M, Knupp SA, Soto-Feliciano Y, Hu X, Kaplan DL, Langer R, Anderson DG, Xu Q. Combinatorial library of lipidoids for in vitro DNA delivery. Bioconjugate Chemistry. 23: 135-40. PMID 22148515 DOI: 10.1021/Bc200572W  0.546
2012 Polat BE, Deen WM, Langer R, Blankschtein D. A physical mechanism to explain the delivery of chemical penetration enhancers into skin during transdermal sonophoresis - Insight into the observed synergism. Journal of Controlled Release : Official Journal of the Controlled Release Society. 158: 250-60. PMID 22100440 DOI: 10.1016/J.Jconrel.2011.11.008  0.512
2012 Seto JE, Polat BE, VanVeller B, Lopez RF, Langer R, Blankschtein D. Fluorescent penetration enhancers for transdermal applications. Journal of Controlled Release : Official Journal of the Controlled Release Society. 158: 85-92. PMID 22062691 DOI: 10.1016/J.Jconrel.2011.10.018  0.508
2012 Wang AZ, Langer R, Farokhzad OC. Nanoparticle delivery of cancer drugs Annual Review of Medicine. 63: 185-198. PMID 21888516 DOI: 10.1146/Annurev-Med-040210-162544  0.553
2012 Freed LE, Marquis JC, Langer R, Vunjak-Novakovic G, Emmanual J. Composition of cell-polymer cartilage implants. Biotechnology and Bioengineering. 43: 605-14. PMID 18615760 DOI: 10.1002/Bit.260430710  0.506
2012 Freed LE, Marquis JC, Langer R, Vunjak-Novakovic G. Kinetics of chondrocyte growth in cell-polymer implants. Biotechnology and Bioengineering. 43: 597-604. PMID 18615759 DOI: 10.1002/Bit.260430709  0.5
2012 Shi J, Votruba AR, Xu X, Langer R, Zetter BR, Farokhzad OC. Abstract 2896: Nanoparticle co-delivery of RNAi and chemotherapy for the treatment of drug-resistant cancers Cancer Research. 72: 2896-2896. DOI: 10.1158/1538-7445.Am2012-2896  0.336
2012 Xu X, Xie K, Zhang X, Pridgen E, Langer R, Walker G, Farokhzad O. Abstract 1955: Simultaneous delivery of siRNA and cisplatin by polymer-lipid hybrid nanoparticles sensitizes resistant cancer to chemotherapy Cancer Research. 72: 1955-1955. DOI: 10.1158/1538-7445.Am2012-1955  0.304
2012 Mizrahi B, Stefanescu CF, Yang C, Lawlor MW, Ko D, Langer R, Kohane DS. Corrigendum to “Elasticity and safety of alkoxyethyl cyanoacrylate tissue adhesives” [Acta Biomater. 7 (2011) 3150–3157] Acta Biomaterialia. 8: 458. DOI: 10.1016/J.Actbio.2011.10.015  0.626
2012 Cho WK, Pereira MJMN, Lang N, Lee K, Mureli S, Zumbuehl A, Sundback C, Masiakos PT, Carter DJD, Borenstein J, Ferreira L, Langer R, Karp JM. Gecko-inspired tape-based adhesives Engineering Biomaterials For Regenerative Medicine: Novel Technologies For Clinical Applications. 195-223. DOI: 10.1007/978-1-4614-1080-5_8  0.441
2012 Tekin H, Sanchez JG, Landeros C, Dubbin K, Langer R, Khademhosseini A. Tissue Engineering: Controlling Spatial Organization of Multiple Cell Types in Defined 3D Geometries (Adv. Mater. 41/2012) Advanced Materials. 24: 5542-5542. DOI: 10.1002/Adma.201290252  0.528
2011 Zhou M, Liu H, Venkiteshwaran A, Kilduff J, Anderson DG, Langer R, Belfort G. High throughput discovery of new fouling-resistant surfaces. Journal of Materials Chemistry. 21: 693-704. PMID 28210070 DOI: 10.1039/C0Jm01266A  0.534
2011 Kohane DS, Langer R. Drug delivery and translation. Drug Delivery and Translational Research. 1: 4-6. PMID 25787888 DOI: 10.1007/S13346-010-0002-2  0.655
2011 Gubskaya AV, Bonates TO, Kholodovych V, Hammer P, Welsh WJ, Langer R, Kohn J. Logical Analysis of Data in Structure-Activity Investigation of Polymeric Gene Delivery. Macromolecular Theory and Simulations. 20: 275-285. PMID 25663794 DOI: 10.1002/Mats.201000087  0.507
2011 Hook AL, Yang J, Chen X, Roberts CJ, Mei Y, Anderson DG, Langer R, Alexander MR, Davies MC. Polymers with hydro-responsive topography identified using high throughput AFM of an acrylate microarray. Soft Matter. 7: 7194-7197. PMID 23259005 DOI: 10.1039/C1Sm06063E  0.537
2011 Tekin H, Sanchez JG, Tsinman T, Langer R, Khademhosseini A. Thermoresponsive Platforms for Tissue Engineering and Regenerative Medicine. Aiche Journal. American Institute of Chemical Engineers. 57: 3249-3258. PMID 23105146 DOI: 10.1002/Aic.12801  0.571
2011 Whitehead KA, Dahlman JE, Langer RS, Anderson DG. Silencing or stimulation? siRNA delivery and the immune system. Annual Review of Chemical and Biomolecular Engineering. 2: 77-96. PMID 22432611 DOI: 10.1146/Annurev-Chembioeng-061010-114133  0.734
2011 Cao Y, Arbiser J, D'Amato RJ, D'Amore PA, Ingber DE, Kerbel R, Klagsbrun M, Lim S, Moses MA, Zetter B, Dvorak H, Langer R. Forty-year journey of angiogenesis translational research. Science Translational Medicine. 3: 114rv3. PMID 22190240 DOI: 10.1126/Scitranslmed.3003149  0.749
2011 Chan JM, Rhee JW, Drum CL, Bronson RT, Golomb G, Langer R, Farokhzad OC. In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid-polymeric nanoparticles. Proceedings of the National Academy of Sciences of the United States of America. 108: 19347-52. PMID 22087004 DOI: 10.1073/Pnas.1115945108  0.529
2011 Saha K, Mei Y, Reisterer CM, Pyzocha NK, Yang J, Muffat J, Davies MC, Alexander MR, Langer R, Anderson DG, Jaenisch R. Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions. Proceedings of the National Academy of Sciences of the United States of America. 108: 18714-9. PMID 22065768 DOI: 10.1073/Pnas.1114854108  0.549
2011 Leuschner F, Dutta P, Gorbatov R, Novobrantseva TI, Donahoe JS, Courties G, Lee KM, Kim JI, Markmann JF, Marinelli B, Panizzi P, Lee WW, Iwamoto Y, Milstein S, Epstein-Barash H, ... ... Langer R, et al. Therapeutic siRNA silencing in inflammatory monocytes in mice. Nature Biotechnology. 29: 1005-10. PMID 21983520 DOI: 10.1038/Nbt.1989  0.532
2011 Zoldan J, Karagiannis ED, Lee CY, Anderson DG, Langer R, Levenberg S. The influence of scaffold elasticity on germ layer specification of human embryonic stem cells. Biomaterials. 32: 9612-21. PMID 21963156 DOI: 10.1016/J.Biomaterials.2011.09.012  0.529
2011 Dvir T, Timko BP, Brigham MD, Naik SR, Karajanagi SS, Levy O, Jin H, Parker KK, Langer R, Kohane DS. Nanowired three-dimensional cardiac patches. Nature Nanotechnology. 6: 720-5. PMID 21946708 DOI: 10.1038/Nnano.2011.160  0.781
2011 Dvir T, Bauer M, Schroeder A, Tsui JH, Anderson DG, Langer R, Liao R, Kohane DS. Nanoparticles targeting the infarcted heart. Nano Letters. 11: 4411-4. PMID 21899318 DOI: 10.1021/Nl2025882  0.712
2011 Karp JM, Langer R. Materials science: Dry solution to a sticky problem. Nature. 477: 42-3. PMID 21886155 DOI: 10.1038/477042A  0.503
2011 Malavia NK, Zurakowski D, Schroeder A, Princiotto AM, Laury AR, Barash HE, Sodroski J, Langer R, Madani N, Kohane DS. Liposomes for HIV prophylaxis. Biomaterials. 32: 8663-8. PMID 21862123 DOI: 10.1016/J.Biomaterials.2011.07.068  0.629
2011 Wang L, Jeong KJ, Chiang HH, Zurakowski D, Behlau I, Chodosh J, Dohlman CH, Langer R, Kohane DS. Hydroxyapatite for keratoprosthesis biointegration. Investigative Ophthalmology & Visual Science. 52: 7392-9. PMID 21849419 DOI: 10.1167/Iovs.11-7601  0.647
2011 Zoldan J, Lytton-Jean AK, Karagiannis ED, Deiorio-Haggar K, Bellan LM, Langer R, Anderson DG. Directing human embryonic stem cell differentiation by non-viral delivery of siRNA in 3D culture. Biomaterials. 32: 7793-800. PMID 21835461 DOI: 10.1016/J.Biomaterials.2011.06.057  0.538
2011 Mizrahi B, Irusta S, McKenna M, Stefanescu C, Yedidsion L, Myint M, Langer R, Kohane DS. Microgels for efficient protein purification. Advanced Materials (Deerfield Beach, Fla.). 23: H258-62. PMID 21805505 DOI: 10.1002/Adma.201101258  0.639
2011 Siegwart DJ, Whitehead KA, Nuhn L, Sahay G, Cheng H, Jiang S, Ma M, Lytton-Jean A, Vegas A, Fenton P, Levins CG, Love KT, Lee H, Cortez C, Collins SP, ... ... Langer R, et al. Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery. Proceedings of the National Academy of Sciences of the United States of America. 108: 12996-3001. PMID 21784981 DOI: 10.1073/Pnas.1106379108  0.787
2011 Tekin H, Tsinman T, Sanchez JG, Jones BJ, Camci-Unal G, Nichol JW, Langer R, Khademhosseini A. Responsive micromolds for sequential patterning of hydrogel microstructures. Journal of the American Chemical Society. 133: 12944-7. PMID 21766872 DOI: 10.1021/Ja204266A  0.795
2011 Bonner DK, Leung C, Chen-Liang J, Chingozha L, Langer R, Hammond PT. Intracellular trafficking of polyamidoamine-poly(ethylene glycol) block copolymers in DNA delivery. Bioconjugate Chemistry. 22: 1519-25. PMID 21761838 DOI: 10.1021/Bc200059V  0.625
2011 Whitehead KA, Sahay G, Li GZ, Love KT, Alabi CA, Ma M, Zurenko C, Querbes W, Langer RS, Anderson DG. Synergistic silencing: combinations of lipid-like materials for efficacious siRNA delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1688-94. PMID 21750531 DOI: 10.1038/Mt.2011.141  0.788
2011 Vuorimaa E, Ketola TM, Green JJ, Hanzlíková M, Lemmetyinen H, Langer R, Anderson DG, Urtti A, Yliperttula M. Poly(β-amino ester)-DNA complexes: time-resolved fluorescence and cellular transfection studies. Journal of Controlled Release : Official Journal of the Controlled Release Society. 154: 171-6. PMID 21699928 DOI: 10.1016/J.Jconrel.2011.06.016  0.557
2011 Lytton-Jean AK, Langer R, Anderson DG. Five years of siRNA delivery: spotlight on gold nanoparticles. Small (Weinheim An Der Bergstrasse, Germany). 7: 1932-7. PMID 21681985 DOI: 10.1002/Smll.201100761  0.544
2011 Valencia PM, Hanewich-Hollatz MH, Gao W, Karim F, Langer R, Karnik R, Farokhzad OC. Effects of ligands with different water solubilities on self-assembly and properties of targeted nanoparticles. Biomaterials. 32: 6226-33. PMID 21658757 DOI: 10.1016/J.Biomaterials.2011.04.078  0.701
2011 Chung HJ, Lee H, Bae KH, Lee Y, Park J, Cho SW, Hwang JY, Park H, Langer R, Anderson D, Park TG. Facile synthetic route for surface-functionalized magnetic nanoparticles: cell labeling and magnetic resonance imaging studies. Acs Nano. 5: 4329-36. PMID 21619063 DOI: 10.1021/Nn201198F  0.747
2011 Mizrahi B, Stefanescu CF, Yang C, Lawlor MW, Ko D, Langer R, Kohane DS. Elasticity and safety of alkoxyethyl cyanoacrylate tissue adhesives. Acta Biomaterialia. 7: 3150-7. PMID 21569875 DOI: 10.1016/J.Actbio.2011.04.022  0.671
2011 Karajanagi SS, Lopez-Guerra G, Park H, Kobler JB, Galindo M, Aanestad J, Mehta DD, Kumai Y, Giordano N, d'Almeida A, Heaton JT, Langer R, Herrera VL, Faquin W, Hillman RE, et al. Assessment of canine vocal fold function after injection of a new biomaterial designed to treat phonatory mucosal scarring. The Annals of Otology, Rhinology, and Laryngology. 120: 175-84. PMID 21510143 DOI: 10.1177/000348941112000306  0.305
2011 Hwang NS, Im SG, Wu PB, Bichara DA, Zhao X, Randolph MA, Langer R, Anderson DG. Chondrogenic priming adipose-mesenchymal stem cells for cartilage tissue regeneration. Pharmaceutical Research. 28: 1395-405. PMID 21494923 DOI: 10.1007/S11095-011-0445-2  0.542
2011 Tekin H, Ozaydin-Ince G, Tsinman T, Gleason KK, Langer R, Khademhosseini A, Demirel MC. Responsive microgrooves for the formation of harvestable tissue constructs. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 5671-9. PMID 21449596 DOI: 10.1021/La200183X  0.574
2011 Rhee M, Valencia PM, Rodriguez MI, Langer R, Farokhzad OC, Karnik R. Synthesis of size-tunable polymeric nanoparticles enabled by 3D hydrodynamic flow focusing in single-layer microchannels. Advanced Materials (Deerfield Beach, Fla.). 23: H79-83. PMID 21433105 DOI: 10.1002/Adma.201004333  0.714
2011 Dang TT, Bratlie KM, Bogatyrev SR, Chen XY, Langer R, Anderson DG. Spatiotemporal effects of a controlled-release anti-inflammatory drug on the cellular dynamics of host response. Biomaterials. 32: 4464-70. PMID 21429573 DOI: 10.1016/J.Biomaterials.2011.02.048  0.545
2011 Cheng H, Hill PS, Siegwart DJ, Vacanti N, Lytton-Jean AK, Cho SW, Ye A, Langer R, Anderson DG. A novel family of biodegradable poly(ester amide) elastomers. Advanced Materials (Deerfield Beach, Fla.). 23: H95-100. PMID 21394790 DOI: 10.1002/Adma.201003482  0.579
2011 Hoare T, Timko BP, Santamaria J, Goya GF, Irusta S, Lau S, Stefanescu CF, Lin D, Langer R, Kohane DS. Magnetically triggered nanocomposite membranes: a versatile platform for triggered drug release. Nano Letters. 11: 1395-400. PMID 21344911 DOI: 10.1021/Nl200494T  0.785
2011 Karajanagi SS, Yoganathan R, Mammucari R, Park H, Cox J, Zeitels SM, Langer R, Foster NR. Application of a dense gas technique for sterilizing soft biomaterials. Biotechnology and Bioengineering. 108: 1716-25. PMID 21337339 DOI: 10.1002/Bit.23105  0.316
2011 Chan EP, Karp JM, Langer RS. A "Self-Pinning" Adhesive Based on Responsive Surface Wrinkles. Journal of Polymer Science. Part B, Polymer Physics. 49: 40-44. PMID 21293787 DOI: 10.1002/Polb.22165  0.514
2011 Polat BE, Hart D, Langer R, Blankschtein D. Ultrasound-mediated transdermal drug delivery: mechanisms, scope, and emerging trends. Journal of Controlled Release : Official Journal of the Controlled Release Society. 152: 330-48. PMID 21238514 DOI: 10.1016/J.Jconrel.2011.01.006  0.54
2011 Polat BE, Lin S, Mendenhall JD, VanVeller B, Langer R, Blankschtein D. Experimental and molecular dynamics investigation into the amphiphilic nature of sulforhodamine B. The Journal of Physical Chemistry. B. 115: 1394-402. PMID 21222449 DOI: 10.1021/Jp109866Q  0.516
2011 Scott AW, Tyler BM, Masi BC, Upadhyay UM, Patta YR, Grossman R, Basaldella L, Langer RS, Brem H, Cima MJ. Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model. Biomaterials. 32: 2532-9. PMID 21220172 DOI: 10.1016/J.Biomaterials.2010.12.020  0.329
2011 Dvir T, Timko BP, Kohane DS, Langer R. Nanotechnological strategies for engineering complex tissues. Nature Nanotechnology. 6: 13-22. PMID 21151110 DOI: 10.1038/Nnano.2010.246  0.775
2011 Liu WF, Ma M, Bratlie KM, Dang TT, Langer R, Anderson DG. Real-time in vivo detection of biomaterial-induced reactive oxygen species. Biomaterials. 32: 1796-801. PMID 21146868 DOI: 10.1016/J.Biomaterials.2010.11.029  0.541
2011 Lopez RF, Seto JE, Blankschtein D, Langer R. Enhancing the transdermal delivery of rigid nanoparticles using the simultaneous application of ultrasound and sodium lauryl sulfate. Biomaterials. 32: 933-41. PMID 20971504 DOI: 10.1016/J.Biomaterials.2010.09.060  0.537
2011 Polat BE, Seto JE, Blankschtein D, Langer R. Application of the aqueous porous pathway model to quantify the effect of sodium lauryl sulfate on ultrasound-induced skin structural perturbation. Journal of Pharmaceutical Sciences. 100: 1387-97. PMID 20963845 DOI: 10.1002/Jps.22361  0.497
2011 Pritchard CD, O'Shea TM, Siegwart DJ, Calo E, Anderson DG, Reynolds FM, Thomas JA, Slotkin JR, Woodard EJ, Langer R. An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate. Biomaterials. 32: 587-97. PMID 20880573 DOI: 10.1016/J.Biomaterials.2010.08.106  0.581
2011 Polat BE, Figueroa PL, Blankschtein D, Langer R. Transport pathways and enhancement mechanisms within localized and non-localized transport regions in skin treated with low-frequency sonophoresis and sodium lauryl sulfate. Journal of Pharmaceutical Sciences. 100: 512-29. PMID 20740667 DOI: 10.1002/Jps.22280  0.501
2011 Kaji H, Camci-Unal G, Langer R, Khademhosseini A. Engineering systems for the generation of patterned co-cultures for controlling cell-cell interactions. Biochimica Et Biophysica Acta. 1810: 239-50. PMID 20655984 DOI: 10.1016/J.Bbagen.2010.07.002  0.785
2011 Langer R, Vacanti JP, Vacanti CA, Atala A, Freed LE, Vunjak-Novakovic G. Tissue engineering: biomedical applications. Tissue Engineering. 1: 151-61. PMID 19877924 DOI: 10.1089/Ten.1995.1.151  0.647
2011 Wang J, Kniazeva T, Campbell CF, Langer R, Ustin JS, Borenstein JT. Biodegradable Microfluidic Scaffolds with Tunable Degradation Properties from Amino Alcohol-based Poly(ester amide) Elastomers Mrs Proceedings. 1299. DOI: 10.1557/Opl.2011.377  0.603
2011 Jeong KJ, Wang L, Stefanescu CF, Lawlor MW, Polat J, Dohlman CH, Langer RS, Kohane DS. Polydopamine coatings enhance biointegration of a model polymeric implant Soft Matter. 7: 8305-8312. DOI: 10.1039/C1Sm05918A  0.674
2011 Zhou M, Liu H, Venkiteshwaran A, Kilduff J, Anderson DG, Langer R, Belfort G. High throughput discovery of new fouling-resistant surfaces Journal of Materials Chemistry. 21: 693-704. DOI: 10.1039/c0jm01266a  0.425
2011 Rhee M, Valencia PM, Rodriguez MI, Langer R, Farokhzad OC, Karnik R. MICROFLUIDICS: Synthesis of Size‐Tunable Polymeric Nanoparticles Enabled by 3D Hydrodynamic Flow Focusing in Single‐Layer Microchannels (Adv. Mater. 12/2011) Advanced Materials. 23. DOI: 10.1002/Adma.201190043  0.587
2010 De Sousa FB, Guerreiro JD, Ma M, Anderson DG, Drum CL, Sinisterra RD, Langer R. Photo-response behavior of electrospun nanofibers based on spiropyran-cyclodextrin modified polymer. Journal of Materials Chemistry. 20: 9910-9917. PMID 28210069 DOI: 10.1039/C0Jm01903H  0.558
2010 Park H, Yip MC, Chertok B, Kost J, Kobler JB, Langer R, Zeitels SM. Indirect low-intensity ultrasonic stimulation for tissue engineering. Journal of Tissue Engineering. 2010: 973530. PMID 21350648 DOI: 10.4061/2010/973530  0.658
2010 Wang J, Bettinger CJ, Langer RS, Borenstein JT. Biodegradable microfluidic scaffolds for tissue engineering from amino alcohol-based poly(ester amide) elastomers. Organogenesis. 6: 212-6. PMID 21220957 DOI: 10.4161/Org.6.4.12909  0.725
2010 Burgess P, Hutt PB, Farokhzad OC, Langer R, Minick S, Zale S. On firm ground: IP protection of therapeutic nanoparticles Nature Biotechnology. 28: 1267-1270. PMID 21139609 DOI: 10.1038/Nbt.1725  0.526
2010 Polat BE, Blankschtein D, Langer R. Low-frequency sonophoresis: application to the transdermal delivery of macromolecules and hydrophilic drugs. Expert Opinion On Drug Delivery. 7: 1415-32. PMID 21118031 DOI: 10.1517/17425247.2010.538679  0.561
2010 Maloney JM, Nikova D, Lautenschläger F, Clarke E, Langer R, Guck J, Van Vliet KJ. Mesenchymal stem cell mechanics from the attached to the suspended state. Biophysical Journal. 99: 2479-87. PMID 20959088 DOI: 10.1016/J.Bpj.2010.08.052  0.725
2010 Davies MC, Alexander MR, Hook AL, Yang J, Mei Y, Taylor M, Urquhart AJ, Langer R, Anderson DG. High throughput surface characterization: A review of a new tool for screening prospective biomedical material arrays. Journal of Drug Targeting. 18: 741-51. PMID 20945971 DOI: 10.3109/1061186X.2010.521941  0.534
2010 Kolishetti N, Dhar S, Valencia PM, Lin LQ, Karnik R, Lippard SJ, Langer R, Farokhzad OC. Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. Proceedings of the National Academy of Sciences of the United States of America. 107: 17939-44. PMID 20921363 DOI: 10.1073/Pnas.1011368107  0.791
2010 Yang J, Mei Y, Hook AL, Taylor M, Urquhart AJ, Bogatyrev SR, Langer R, Anderson DG, Davies MC, Alexander MR. Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays. Biomaterials. 31: 8827-38. PMID 20832108 DOI: 10.1016/J.Biomaterials.2010.08.028  0.556
2010 Mei Y, Hollister-Lock J, Bogatyrev SR, Cho SW, Weir GC, Langer R, Anderson DG. A high throughput micro-array system of polymer surfaces for the manipulation of primary pancreatic islet cells. Biomaterials. 31: 8989-95. PMID 20828808 DOI: 10.1016/J.Biomaterials.2010.08.029  0.569
2010 Elman NM, Masi BC, Cima MJ, Langer R. Electro-thermally induced structural failure actuator (ETISFA) for implantable controlled drug delivery devices based on Micro-Electro-Mechanical- Systems Lab On a Chip - Miniaturisation For Chemistry and Biology. 10: 2796-2804. PMID 20820485 DOI: 10.1039/C005135G  0.317
2010 Huang YH, Cozzitorto JA, Richards NG, Eltoukhy AA, Yeo CJ, Langer R, Anderson DG, Brody JR, Sawicki JA. CanScript, an 18-Base pair DNA sequence, boosts tumor cell-specific promoter activity: implications for targeted gene therapy. Cancer Biology & Therapy. 10: 878-84. PMID 20798601 DOI: 10.4161/Cbt.10.9.13234  0.528
2010 Mei Y, Saha K, Bogatyrev SR, Yang J, Hook AL, Kalcioglu ZI, Cho SW, Mitalipova M, Pyzocha N, Rojas F, Van Vliet KJ, Davies MC, Alexander MR, Langer R, Jaenisch R, et al. Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells. Nature Materials. 9: 768-78. PMID 20729850 DOI: 10.1038/Nmat2812  0.532
2010 Shi J, Votruba AR, Farokhzad OC, Langer R. Nanotechnology in drug delivery and tissue engineering: from discovery to applications. Nano Letters. 10: 3223-30. PMID 20726522 DOI: 10.1021/Nl102184C  0.56
2010 Mahon KP, Love KT, Whitehead KA, Qin J, Akinc A, Leshchiner E, Leshchiner I, Langer R, Anderson DG. Combinatorial approach to determine functional group effects on lipidoid-mediated siRNA delivery. Bioconjugate Chemistry. 21: 1448-54. PMID 20715849 DOI: 10.1021/Bc100041R  0.761
2010 Gao W, Langer R, Farokhzad OC. Poly(ethylene glycol) with observable shedding. Angewandte Chemie (International Ed. in English). 49: 6567-71. PMID 20677297 DOI: 10.1002/Anie.201001868  0.528
2010 Tekin H, Anaya M, Brigham MD, Nauman C, Langer R, Khademhosseini A. Stimuli-responsive microwells for formation and retrieval of cell aggregates. Lab On a Chip. 10: 2411-8. PMID 20664846 DOI: 10.1039/C004732E  0.562
2010 Yang F, Cho SW, Son SM, Hudson SP, Bogatyrev S, Keung L, Kohane DS, Langer R, Anderson DG. Combinatorial extracellular matrices for human embryonic stem cell differentiation in 3D. Biomacromolecules. 11: 1909-14. PMID 20614932 DOI: 10.1021/Bm100357T  0.727
2010 Bruggeman JP, Bettinger CJ, Langer R. Biodegradable xylitol-based elastomers: in vivo behavior and biocompatibility. Journal of Biomedical Materials Research. Part A. 95: 92-104. PMID 20540093 DOI: 10.1002/Jbm.A.32733  0.608
2010 Wang AZ, Yuet K, Zhang L, Gu FX, Huynh-Le M, Radovic-Moreno AF, Kantoff PW, Bander NH, Langer R, Farokhzad OC. ChemoRad nanoparticles: a novel multifunctional nanoparticle platform for targeted delivery of concurrent chemoradiation. Nanomedicine (London, England). 5: 361-8. PMID 20394530 DOI: 10.2217/Nnm.10.6  0.54
2010 Gao W, Xiao Z, Radovic-Moreno A, Shi J, Langer R, Farokhzad OC. Progress in siRNA delivery using multifunctional nanoparticles. Methods in Molecular Biology (Clifton, N.J.). 629: 53-67. PMID 20387142 DOI: 10.1007/978-1-60761-657-3_4  0.568
2010 Bratlie KM, Dang TT, Lyle S, Nahrendorf M, Weissleder R, Langer R, Anderson DG. Rapid biocompatibility analysis of materials via in vivo fluorescence imaging of mouse models. Plos One. 5: e10032. PMID 20386609 DOI: 10.1371/Journal.Pone.0010032  0.551
2010 Epstein-Barash H, Orbey G, Polat BE, Ewoldt RH, Feshitan J, Langer R, Borden MA, Kohane DS. A microcomposite hydrogel for repeated on-demand ultrasound-triggered drug delivery. Biomaterials. 31: 5208-17. PMID 20347484 DOI: 10.1016/J.Biomaterials.2010.03.008  0.678
2010 Seto JE, Polat BE, Lopez RF, Blankschtein D, Langer R. Effects of ultrasound and sodium lauryl sulfate on the transdermal delivery of hydrophilic permeants: Comparative in vitro studies with full-thickness and split-thickness pig and human skin. Journal of Controlled Release : Official Journal of the Controlled Release Society. 145: 26-32. PMID 20346994 DOI: 10.1016/J.Jconrel.2010.03.013  0.535
2010 Chan JM, Valencia PM, Zhang L, Langer R, Farokhzad OC. Polymeric nanoparticles for drug delivery. Methods in Molecular Biology (Clifton, N.J.). 624: 163-75. PMID 20217595 DOI: 10.1007/978-1-60761-609-2_11  0.575
2010 Alexis F, Pridgen EM, Langer R, Farokhzad OC. Nanoparticle Technologies for Cancer Therapy Handbook of Experimental Pharmacology. 197: 55-86. PMID 20217526 DOI: 10.1007/978-3-642-00477-3_2  0.555
2010 Shapiro MG, Westmeyer GG, Romero PA, Szablowski JO, Küster B, Shah A, Otey CR, Langer R, Arnold FH, Jasanoff A. Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine. Nature Biotechnology. 28: 264-70. PMID 20190737 DOI: 10.1038/Nbt.1609  0.759
2010 Valencia PM, Basto PA, Zhang L, Rhee M, Langer R, Farokhzad OC, Karnik R. Single-step assembly of homogenous lipid-polymeric and lipid-quantum dot nanoparticles enabled by microfluidic rapid mixing. Acs Nano. 4: 1671-9. PMID 20166699 DOI: 10.1021/Nn901433U  0.695
2010 Luo Y, Kobler JB, Heaton JT, Jia X, Zeitels SM, Langer R. Injectable hyaluronic acid-dextran hydrogels and effects of implantation in ferret vocal fold. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 93: 386-93. PMID 20151459 DOI: 10.1002/Jbm.B.31593  0.339
2010 Mamo T, Moseman EA, Kolishetti N, Salvador-Morales C, Shi J, Kuritzkes DR, Langer R, von Andrian U, Farokhzad OC. Emerging nanotechnology approaches for HIV/AIDS treatment and prevention. Nanomedicine (London, England). 5: 269-85. PMID 20148638 DOI: 10.2217/Nnm.10.1  0.721
2010 Chan JM, Zhang L, Tong R, Ghosh D, Gao W, Liao G, Yuet KP, Gray D, Rhee JW, Cheng J, Golomb G, Libby P, Langer R, Farokhzad OC. Spatiotemporal controlled delivery of nanoparticles to injured vasculature. Proceedings of the National Academy of Sciences of the United States of America. 107: 2213-8. PMID 20133865 DOI: 10.1073/Pnas.0914585107  0.581
2010 Cheng H, Kastrup CJ, Ramanathan R, Siegwart DJ, Ma M, Bogatyrev SR, Xu Q, Whitehead KA, Langer R, Anderson DG. Nanoparticulate cellular patches for cell-mediated tumoritropic delivery. Acs Nano. 4: 625-31. PMID 20121215 DOI: 10.1021/Nn901319Y  0.762
2010 Love KT, Mahon KP, Levins CG, Whitehead KA, Querbes W, Dorkin JR, Qin J, Cantley W, Qin LL, Racie T, Frank-Kamenetsky M, Yip KN, Alvarez R, Sah DW, de Fougerolles A, ... ... Langer R, et al. Lipid-like materials for low-dose, in vivo gene silencing. Proceedings of the National Academy of Sciences of the United States of America. 107: 1864-9. PMID 20080679 DOI: 10.1073/Pnas.0910603106  0.739
2010 Schroeder A, Levins CG, Cortez C, Langer R, Anderson DG. Lipid-based nanotherapeutics for siRNA delivery. Journal of Internal Medicine. 267: 9-21. PMID 20059641 DOI: 10.1111/J.1365-2796.2009.02189.X  0.565
2010 Fisher OZ, Khademhosseini A, Langer R, Peppas NA. Bioinspired materials for controlling stem cell fate. Accounts of Chemical Research. 43: 419-28. PMID 20043634 DOI: 10.1021/Ar900226Q  0.678
2010 Pritchard CD, Arnér KM, Neal RA, Neeley WL, Bojo P, Bachelder E, Holz J, Watson N, Botchwey EA, Langer RS, Ghosh FK. The use of surface modified poly(glycerol-co-sebacic acid) in retinal transplantation. Biomaterials. 31: 2153-62. PMID 19962754 DOI: 10.1016/J.Biomaterials.2009.11.074  0.612
2010 Hudson SP, Langer R, Fink GR, Kohane DS. Injectable in situ cross-linking hydrogels for local antifungal therapy. Biomaterials. 31: 1444-52. PMID 19942285 DOI: 10.1016/J.Biomaterials.2009.11.016  0.679
2010 Dvir T, Banghart MR, Timko BP, Langer R, Kohane DS. Photo-targeted nanoparticles. Nano Letters. 10: 250-4. PMID 19904979 DOI: 10.1021/Nl903411S  0.786
2010 Harris TJ, Green JJ, Fung PW, Langer R, Anderson DG, Bhatia SN. Tissue-specific gene delivery via nanoparticle coating. Biomaterials. 31: 998-1006. PMID 19850333 DOI: 10.1016/J.Biomaterials.2009.10.012  0.659
2010 Hook AL, Anderson DG, Langer R, Williams P, Davies MC, Alexander MR. High throughput methods applied in biomaterial development and discovery. Biomaterials. 31: 187-98. PMID 19815273 DOI: 10.1016/J.Biomaterials.2009.09.037  0.572
2010 Yang F, Cho SW, Son SM, Bogatyrev SR, Singh D, Green JJ, Mei Y, Park S, Bhang SH, Kim BS, Langer R, Anderson DG. Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles. Proceedings of the National Academy of Sciences of the United States of America. 107: 3317-22. PMID 19805054 DOI: 10.1073/Pnas.0905432106  0.565
2010 Park H, Karajanagi S, Wolak K, Aanestad J, Daheron L, Kobler JB, Lopez-Guerra G, Heaton JT, Langer RS, Zeitels SM. Three-dimensional hydrogel model using adipose-derived stem cells for vocal fold augmentation. Tissue Engineering. Part A. 16: 535-43. PMID 19728785 DOI: 10.1089/Ten.Tea.2009.0029  0.31
2010 Hoare T, Zurakowski D, Langer R, Kohane DS. Rheological blends for drug delivery. I. Characterization in vitro. Journal of Biomedical Materials Research. Part A. 92: 575-85. PMID 19235215 DOI: 10.1002/Jbm.A.32392  0.68
2010 Leckband D, Langer R. An approach for the stable immobilization of proteins. Biotechnology and Bioengineering. 37: 227-37. PMID 18597360 DOI: 10.1002/Bit.260370305  0.531
2010 Sawicki JA, Huang Y, Cozzitorto J, Langer R, Anderson DG, Brody JR. Abstract 2: Naked CanScript, an 18-base pair sequence, has tumor cell-specific promoter activity in vivo: Implications for targeted gene therapy Cancer Research. 70: 2-2. DOI: 10.1158/1538-7445.Am10-2  0.537
2010 Kohane DS, Langer R. Biocompatibility and drug delivery systems Chemical Science. 1: 441-446. DOI: 10.1039/C0Sc00203H  0.673
2010 De Sousa FB, Guerreiro JDT, Ma M, Anderson DG, Drum CL, Sinisterra RD, Langer R. Photo-response behavior of electrospun nanofibers based on spiropyran-cyclodextrin modified polymer Journal of Materials Chemistry. 20: 9910-9917. DOI: 10.1039/c0jm01903h  0.473
2010 Whitehead KA, Langer R, Anderson DG. Knocking down barriers: Advances in siRNA delivery (Nature Reviews Drug Discovery (2009) 8 (129-138) DOI:10.1038/nrd2742) Nature Reviews Drug Discovery. 9: 412. DOI: 10.1038/nrd3182  0.726
2010 Khademhosseini A, Rajalingam B, Jinno S, Langer R. Nanoengineered Systems for Tissue Engineering and Regeneration Nanotechnology. DOI: 10.1002/9783527628155.Nanotech061  0.567
2010 Zoldan J, Kraehenbuehl TP, Lytton-Jean AKR, Langer RS, Anderson DG. Tissue Engineering for Stem Cell Mediated Regenerative Medicine Human Stem Cell Technology and Biology: a Research Guide and Laboratory Manual. 377-399. DOI: 10.1002/9780470889909.ch31  0.473
2009 Mei Y, Gerecht S, Taylor M, Urquhart AJ, Bogatyrev SR, Cho SW, Davies MC, Alexander MR, Langer RS, Anderson DG. Mapping the Interactions among Biomaterials, Adsorbed Proteins, and Human Embryonic Stem Cells. Advanced Materials (Deerfield Beach, Fla.). 21: 2781-2786. PMID 28794580 DOI: 10.1002/Adma.200803184  0.549
2009 Taylor M, Urquhart AJ, Anderson DG, Langer R, Davies MC, Alexander MR. Partial least squares regression as a powerful tool for investigating large combinatorial polymer libraries. Surface and Interface Analysis : Sia. 41: 127-135. PMID 25414534 DOI: 10.1002/Sia.2969  0.516
2009 Sunshine J, Green JJ, Mahon KP, Yang F, Eltoukhy AA, Nguyen DN, Langer R, Anderson DG. Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy. Advanced Materials (Deerfield Beach, Fla.). 21: 4947-4951. PMID 25165411 DOI: 10.1002/Adma.200901718  0.575
2009 Cho SW, Goldberg M, Son SM, Xu Q, Yang F, Mei Y, Bogatyrev S, Langer R, Anderson DG. Lipid-like Nanoparticles for Small Interfering RNA Delivery to Endothelial Cells. Advanced Functional Materials. 19: 3112-3118. PMID 23393492 DOI: 10.1002/Adfm.200900519  0.566
2009 Stone GW, Barzee S, Snarsky V, Santucci C, Tran B, Langer R, Zugates GT, Anderson DG, Kornbluth RS. Nanoparticle-delivered multimeric soluble CD40L DNA combined with Toll-Like Receptor agonists as a treatment for melanoma. Plos One. 4: e7334. PMID 19812695 DOI: 10.1371/Journal.Pone.0007334  0.538
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