Year |
Citation |
Score |
2005 |
Llinás A, Ahmed N, Cordaro M, Laws AP, Frère JM, Delmarcelle M, Silvaggi NR, Kelly JA, Page MI. Inactivation of bacterial DD-peptidase by beta-sultams. Biochemistry. 44: 7738-46. PMID 15909988 DOI: 10.1021/Bi050110O |
0.716 |
|
2005 |
Silvaggi NR, Josephine HR, Kuzin AP, Nagarajan R, Pratt RF, Kelly JA. Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin". Journal of Molecular Biology. 345: 521-33. PMID 15581896 DOI: 10.1016/J.Jmb.2004.10.076 |
0.728 |
|
2004 |
Silvaggi NR, Kaur K, Adediran SA, Pratt RF, Kelly JA. Toward better antibiotics: crystallographic studies of a novel class of DD-peptidase/beta-lactamase inhibitors. Biochemistry. 43: 7046-53. PMID 15170342 DOI: 10.1021/Bi049612C |
0.733 |
|
2003 |
Silvaggi NR, Anderson JW, Brinsmade SR, Pratt RF, Kelly JA. The crystal structure of phosphonate-inhibited D-Ala-D-Ala peptidase reveals an analogue of a tetrahedral transition state. Biochemistry. 42: 1199-208. PMID 12564922 DOI: 10.1021/Bi0268955 |
0.726 |
|
2002 |
McDonough MA, Anderson JW, Silvaggi NR, Pratt RF, Knox JR, Kelly JA. Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins. Journal of Molecular Biology. 322: 111-22. PMID 12215418 DOI: 10.1016/S0022-2836(02)00742-8 |
0.737 |
|
2002 |
Kelly JA, Brinsmade SR, Silvaggi NR. Trapping reaction intermediates: a transition state on the R61 DD-peptidase catalytic pathway Acta Crystallographica Section a Foundations of Crystallography. 58: c103-c103. DOI: 10.1107/S0108767302089146 |
0.612 |
|
2001 |
Lee W, McDonough MA, Kotra LP, Li ZH, Silvaggi NR, Takeda Y, Kelly JA, Mobashery S. A 1.2-Å snapshot of the final step of bacterial cell wall biosynthesis Proceedings of the National Academy of Sciences of the United States of America. 98: 1427-1431. PMID 11171967 DOI: 10.1073/Pnas.98.4.1427 |
0.708 |
|
1999 |
McDonough MA, Klei HE, Kelly JA. Crystal structure of penicillin G acylase from the Brol mutant strain of Providencia rettgeri Protein Science. 8: 1971-1981. PMID 10548042 DOI: 10.1110/Ps.8.10.1971 |
0.479 |
|
1998 |
Kelly JA, Kuzin AP, Charlier P, Fonzé E. X-ray studies of enzymes that interact with penicillins. Cellular and Molecular Life Sciences : Cmls. 54: 353-8. PMID 9614972 DOI: 10.1007/S000180050163 |
0.484 |
|
1995 |
Klei HE, Daumy GO, Kelly JA. Purification and preliminary crystallographic studies of penicillin G acylase from Providencia rettgeri Protein Science. 4: 433-441. PMID 7795527 DOI: 10.1002/Pro.5560040310 |
0.355 |
|
1995 |
Lamotte-Brasseur J, Knox J, Kelly JA, Charlier P, Fonzé E, Dideberg O, Frére JM. The structures and catalytic mechanisms of active-site serine beta-lactamases. Biotechnology & Genetic Engineering Reviews. 12: 189-230. PMID 7727028 DOI: 10.1080/02648725.1994.10647912 |
0.514 |
|
1995 |
Kuzin AP, Liu H, Kelly JA, Knox JR. Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases. Biochemistry. 34: 9532-40. PMID 7626623 DOI: 10.1021/Bi00029A030 |
0.581 |
|
1995 |
Kelly JA, Kuzin AP. The refined crystallographic structure of a DD-peptidase penicillin-target enzyme at 1.6 Å resolution Journal of Molecular Biology. 254: 223-236. PMID 7490745 DOI: 10.1006/Jmbi.1995.0613 |
0.47 |
|
1992 |
Joris B, Ledent P, Dideberg O, Fonzé E, Lamotte-Brasseur J, Kelly JA, Ghuysen JM, Frère JM. Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins. Antimicrobial Agents and Chemotherapy. 35: 2294-301. PMID 1804001 DOI: 10.1128/Aac.35.11.2294 |
0.536 |
|
1992 |
Kelly JA, Waley SG, Adam M, Frère JM. Crystalline enzyme kinetics: activity of the Streptomyces R61 d-alanyl-d-alanine peptidase Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 1119: 256-260. PMID 1547270 DOI: 10.1016/0167-4838(92)90211-U |
0.327 |
|
1990 |
Kelly JA, Knox JR, Zhao H, Frère JM, Ghaysen JM. Crystallographic mapping of beta-lactams bound to a D-alanyl-D-alanine peptidase target enzyme. Journal of Molecular Biology. 209: 281-95. PMID 2585485 DOI: 10.1016/0022-2836(89)90277-5 |
0.6 |
|
1989 |
Kelly JA, Knox JR, Zhao H. Studying enzyme-β-lactam interactions using X-ray diffraction Journal of Molecular Graphics. 7: 87-92. PMID 2488268 DOI: 10.1016/S0263-7855(89)80005-0 |
0.44 |
|
1988 |
Joris B, Ghuysen JM, Dive G, Renard A, Dideberg O, Charlier P, Frère JM, Kelly JA, Boyington JC, Moews PC. The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family. The Biochemical Journal. 250: 313-24. PMID 3128280 DOI: 10.1042/Bj2500313 |
0.489 |
|
1986 |
Kelly JA, Dideberg O, Charlier P, Wery JP, Libert M, Moews PC, Knox JR, Duez C, Fraipont C, Joris B. On the origin of bacterial resistance to penicillin: comparison of a beta-lactamase and a penicillin target. Science (New York, N.Y.). 231: 1429-31. PMID 3082007 DOI: 10.1126/Science.3082007 |
0.597 |
|
1986 |
Kelly JA, Knox JR, Moews PC, Hite GJ, Bartolone JB, Zhao H, Joris B, Frère J, Ghuysen J. 2.8-A Structure of penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase from Streptomyces R61 and complexes with beta-lactams. Journal of Biological Chemistry. 260: 6449-6458. DOI: 10.2210/Pdb1Pte/Pdb |
0.57 |
|
1984 |
Frère J, Klein D, Kelly JA, Ghuysen J. Interaction between monobactams and model d-alanyl-d-alanine-cleaving peptidases Fems Microbiology Letters. 21: 213-217. DOI: 10.1111/J.1574-6968.1984.Tb00213.X |
0.486 |
|
1982 |
Kelly JA, Moews PC, Knox JR, Frère JM, Ghuysen JM. Penicillin target enzyme and the antibiotic binding site. Science (New York, N.Y.). 218: 479-81. PMID 7123246 DOI: 10.1126/Science.7123246 |
0.573 |
|
1982 |
Frère JM, Kelly JA, Klein D, Ghuysen JM, Claes P, Vanderhaeghe H. Delta 2- and delta 3-cephalosporins, penicillinate and 6-unsubstituted penems. Intrinsic reactivity and interaction with beta-lactamases and D-alanyl-D-alanine-cleaving serine peptidases. The Biochemical Journal. 203: 223-34. PMID 6980645 DOI: 10.1042/Bj2030223 |
0.488 |
|
1981 |
Kelly JA, Frere JM, Klein D, Ghuysen JM. Interaction between non-classical β-lactam compounds and the Zn2+-containing G and serine R61 and R39 D-alanyl-D-alanine peptidases Biochemical Journal. 199: 129-136. PMID 6279094 DOI: 10.1042/Bj1990129 |
0.395 |
|
1979 |
Kelly JA, Sielecki AR, Sykes BD, James MN, Phillips DC. X-ray crystallography of the binding of the bacterial cell wall trisaccharide NAM-NAG-NAM to lysozyme. Nature. 282: 875-8. PMID 514367 DOI: 10.1038/282875A0 |
0.51 |
|
1979 |
Knox JR, DeLucia ML, Murthy NS, Kelly JA, Moews PC, Frére JM, Ghuysen JM. Crystallographic data for a penicillin receptor: Exocellular dd-carboxypeptidase-transpeptidase from Streptomyces R61 Journal of Molecular Biology. 127: 217-218. PMID 430564 DOI: 10.1016/0022-2836(79)90241-9 |
0.333 |
|
1976 |
Knox JR, Kelly JA, Moews PC, Murthy NS. 5-5A crystallographic structure of penicillin beta-lactamase and radius of gyration in solution. Journal of Molecular Biology. 104: 865-75. PMID 785016 DOI: 10.1016/0022-2836(76)90187-X |
0.408 |
|
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