| Year |
Citation |
Score |
| 2023 |
Morgan MAJ, Mohammad Parast S, Iwanaszko M, Aoi Y, Yoo D, Dumar ZJ, Howard BC, Helmin KA, Liu Q, Thakur WR, Zeidner JM, Singer BD, Eichler EE, Shilatifard A. : A primate-specific RNA polymerase II elongation factor encoded by a tandem repeat gene cluster. Science Advances. 9: eadj1261. PMID 37992162 DOI: 10.1126/sciadv.adj1261 |
0.32 |
|
| 2023 |
Aoi Y, Shilatifard A. Transcriptional elongation control in developmental gene expression, aging, and disease. Molecular Cell. PMID 37922911 DOI: 10.1016/j.molcel.2023.10.004 |
0.382 |
|
| 2023 |
Zheng B, Gold S, Iwanaszko M, Howard BC, Wang L, Shilatifard A. Distinct layers of BRD4-PTEFb reveal bromodomain-independent function in transcriptional regulation. Molecular Cell. PMID 37442129 DOI: 10.1016/j.molcel.2023.06.032 |
0.433 |
|
| 2023 |
Morgan MAJ, Shilatifard A. Epigenetic moonlighting: Catalytic-independent functions of histone modifiers in regulating transcription. Science Advances. 9: eadg6593. PMID 37083523 DOI: 10.1126/sciadv.adg6593 |
0.352 |
|
| 2023 |
Soliman SHA, Cisneros WJ, Iwanaszko M, Aoi Y, Ganesan S, Walter M, Zeidner JM, Mishra RK, Kim EY, Wolinsky SM, Hultquist JF, Shilatifard A. Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C. Science Advances. 9: eadf2468. PMID 36888719 DOI: 10.1126/sciadv.adf2468 |
0.335 |
|
| 2023 |
Forte E, Li M, Ayaloglu Butun F, Hu Q, Borst EM, Schipma MJ, Piunti A, Shilatifard A, Terhune SS, Abecassis M, Meier JL, Hummel M. Critical Role for the Human Cytomegalovirus Major Immediate Early Proteins in Recruitment of RNA Polymerase II and H3K27Ac To an Enhancer-Like Element in Ori. Microbiology Spectrum. e0314422. PMID 36645269 DOI: 10.1128/spectrum.03144-22 |
0.417 |
|
| 2022 |
Zhao Z, Rendleman EJ, Szczepanski AP, Morgan MA, Wang L, Shilatifard A. CARM1-mediated methylation of ASXL2 impairs tumor-suppressive function of MLL3/COMPASS. Science Advances. 8: eadd3339. PMID 36197977 DOI: 10.1126/sciadv.add3339 |
0.358 |
|
| 2022 |
Aoi Y, Shah AP, Ganesan S, Soliman SHA, Cho BK, Goo YA, Kelleher NL, Shilatifard A. SPT6 functions in transcriptional pause/release via PAF1C recruitment. Molecular Cell. PMID 35973425 DOI: 10.1016/j.molcel.2022.06.037 |
0.383 |
|
| 2022 |
Cenik BK, Sze CC, Ryan CA, Das S, Cao K, Douillet D, Rendleman EJ, Zha D, Khan NH, Bartom E, Shilatifard A. A synthetic lethality screen reveals ING5 as a genetic dependency of catalytically dead Set1A/COMPASS in mouse embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 119: e2118385119. PMID 35500115 DOI: 10.1073/pnas.2118385119 |
0.349 |
|
| 2022 |
Morgan M, Shiekhattar R, Shilatifard A, Lauberth SM. It's a DoG-eat-DoG world-altered transcriptional mechanisms drive downstream-of-gene (DoG) transcript production. Molecular Cell. 82: 1981-1991. PMID 35487209 DOI: 10.1016/j.molcel.2022.04.008 |
0.368 |
|
| 2022 |
Ishi Y, Zhang Y, Zhang A, Sasaki T, Piunti A, Suri A, Watanabe J, Abe K, He X, Katagi H, Bhalla P, Natsumeda M, Zou L, Shilatifard A, Hashizume R. Therapeutic Targeting of EZH2 and BET BRD4 in Pediatric Rhabdoid Tumor. Molecular Cancer Therapeutics. PMID 35247919 DOI: 10.1158/1535-7163.MCT-21-0646 |
0.311 |
|
| 2021 |
Morgan MAJ, Popova IK, Vaidya A, Burg JM, Marunde MR, Rendleman EJ, Dumar ZJ, Watson R, Meiners MJ, Howard SA, Khalatyan N, Vaughan RM, Rothbart SB, Keogh MC, Shilatifard A. A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer. Genes & Development. PMID 34819353 DOI: 10.1101/gad.348766.121 |
0.304 |
|
| 2021 |
Aoi Y, Takahashi YH, Shah AP, Iwanaszko M, Rendleman EJ, Khan NH, Cho BK, Goo YA, Ganesan S, Kelleher NL, Shilatifard A. SPT5 stabilization of promoter-proximal RNA polymerase II. Molecular Cell. PMID 34480849 DOI: 10.1016/j.molcel.2021.08.006 |
0.41 |
|
| 2021 |
Piunti A, Shilatifard A. The roles of Polycomb repressive complexes in mammalian development and cancer. Nature Reviews. Molecular Cell Biology. PMID 33723438 DOI: 10.1038/s41580-021-00341-1 |
0.366 |
|
| 2021 |
Katagi H, Takata N, Aoi Y, Zhang Y, Rendleman EJ, Blyth GT, Eckerdt FD, Tomita Y, Sasaki T, Saratsis AM, Kondo A, Goldman S, Becher OJ, Smith E, Zou L, ... Shilatifard A, et al. Therapeutic targeting of transcriptional elongation in diffuse intrinsic pontine glioma. Neuro-Oncology. PMID 33471107 DOI: 10.1093/neuonc/noab009 |
0.347 |
|
| 2021 |
Zheng B, Aoi Y, Shah AP, Iwanaszko M, Das S, Rendleman EJ, Zha D, Khan N, Smith ER, Shilatifard A. Acute perturbation strategies in interrogating RNA polymerase II elongation factor function in gene expression. Genes & Development. PMID 33446572 DOI: 10.1101/gad.346106.120 |
0.412 |
|
| 2020 |
Morgan MAJ, Shilatifard A. Reevaluating the roles of histone-modifying enzymes and their associated chromatin modifications in transcriptional regulation. Nature Genetics. 52: 1271-1281. PMID 33257899 DOI: 10.1038/s41588-020-00736-4 |
0.373 |
|
| 2020 |
Cao K, Ugarenko M, Ozark PA, Wang J, Marshall SA, Rendleman EJ, Liang K, Wang L, Zou L, Smith ER, Yue F, Shilatifard A. DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 33077595 DOI: 10.1073/pnas.2001075117 |
0.369 |
|
| 2020 |
Cenik BK, Shilatifard A. COMPASS and SWI/SNF complexes in development and disease. Nature Reviews. Genetics. PMID 32958894 DOI: 10.1038/S41576-020-0278-0 |
0.444 |
|
| 2020 |
Shilatifard A. COVID-19: Rescue by transcriptional inhibition. Science Advances. 6. PMID 32937442 DOI: 10.1126/Sciadv.Abc6891 |
0.431 |
|
| 2020 |
Liu S, Yin P, Xu J, Dotts AJ, Kujawa SA, Coon V JS, Zhao H, Hilatifard AS, Dai Y, Bulun SE. Targeting DNA methylation depletes uterine leiomyoma stem-cell enriched population by stimulating their differentiation. Endocrinology. PMID 32812024 DOI: 10.1210/Endocr/Bqaa143 |
0.335 |
|
| 2020 |
Beckedorff F, Blumenthal E, daSilva LF, Aoi Y, Cingaram PR, Yue J, Zhang A, Dokaneheifard S, Valencia MG, Gaidosh G, Shilatifard A, Shiekhattar R. The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts. Cell Reports. 32: 107917. PMID 32697989 DOI: 10.1016/J.Celrep.2020.107917 |
0.524 |
|
| 2020 |
Sze CC, Ozark PA, Cao K, Ugarenko M, Das S, Wang L, Marshall SA, Rendleman EJ, Ryan CA, Zha D, Douillet D, Chen FX, Shilatifard A. Coordinated regulation of cellular identity-associated H3K4me3 breadth by the COMPASS family. Science Advances. 6: eaaz4764. PMID 32637595 DOI: 10.1126/Sciadv.Aaz4764 |
0.454 |
|
| 2020 |
Douillet D, Sze CC, Ryan C, Piunti A, Shah AP, Ugarenko M, Marshall SA, Rendleman EJ, Zha D, Helmin KA, Zhao Z, Cao K, Morgan MA, Singer BD, Bartom ET, ... ... Shilatifard A, et al. Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation. Nature Genetics. PMID 32393859 DOI: 10.1038/S41588-020-0618-1 |
0.457 |
|
| 2020 |
Aoi Y, Smith ER, Shah AP, Rendleman EJ, Marshall SA, Woodfin AR, Chen FX, Shiekhattar R, Shilatifard A. NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release. Molecular Cell. PMID 32155413 DOI: 10.1016/J.Molcel.2020.02.014 |
0.48 |
|
| 2020 |
Viéitez C, Martínez-Cebrián G, Solé C, Böttcher R, Potel CM, Savitski MM, Onnebo S, Fabregat M, Shilatifard A, Posas F, de Nadal E. A genetic analysis reveals novel histone residues required for transcriptional reprogramming upon stress. Nucleic Acids Research. PMID 32064518 DOI: 10.1093/Nar/Gkaa081 |
0.422 |
|
| 2020 |
Birch NW, Shilatifard A. The role of histone modifications in leukemogenesis. Journal of Biosciences. 45. PMID 31965984 DOI: 10.1007/S12038-019-9969-0 |
0.41 |
|
| 2020 |
Piunti A, Smith E, Morgan M, Ugarenko M, Khaltyan N, Helmin K, Ryan C, Murray D, Rickels R, Yilmaz B, Rendleman E, Savas J, Singer B, Bulun S, Shilatifard A. Abstract B46: CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb Repressive complex 2 via a H3K27M-like mechanism Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-B46 |
0.495 |
|
| 2019 |
Zhao Z, Shilatifard A. Epigenetic modifications of histones in cancer. Genome Biology. 20: 245. PMID 31747960 DOI: 10.1186/S13059-019-1870-5 |
0.367 |
|
| 2019 |
Yang Y, Joshi M, Takahashi YH, Ning Z, Qu Q, Brunzelle JS, Skiniotis G, Figeys D, Shilatifard A, Couture JF. A non-canonical monovalent zinc finger stabilizes the integration of Cfp1 into the H3K4 methyltransferase complex COMPASS. Nucleic Acids Research. PMID 31724694 DOI: 10.1093/Nar/Gkz1037 |
0.45 |
|
| 2019 |
LeRoy G, Oksuz O, Descostes N, Aoi Y, Ganai RA, Kara HO, Yu JR, Lee CH, Stafford J, Shilatifard A, Reinberg D. LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells. Science Advances. 5: eaay3068. PMID 31616795 DOI: 10.1126/Sciadv.Aay3068 |
0.525 |
|
| 2019 |
Zhao Z, Wang L, Bartom E, Marshall S, Rendleman E, Ryan C, Shilati A, Savas J, Chandel N, Shilatifard A. β-Catenin/Tcf7l2-dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer. Science Advances. 5: eaax0698. PMID 31392276 DOI: 10.1126/Sciadv.Aax0698 |
0.37 |
|
| 2019 |
Piunti A, Smith ER, Morgan MAJ, Ugarenko M, Khaltyan N, Helmin KA, Ryan CA, Murray DC, Rickels RA, Yilmaz BD, Rendleman EJ, Savas JN, Singer BD, Bulun SE, Shilatifard A. CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism. Science Advances. 5: eaax2887. PMID 31281901 DOI: 10.1126/Sciadv.Aax2887 |
0.465 |
|
| 2019 |
Pan J, McKenzie ZM, D'Avino AR, Mashtalir N, Lareau CA, St Pierre R, Wang L, Shilatifard A, Kadoch C. The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting. Nature Genetics. PMID 30858614 DOI: 10.1038/S41588-019-0363-5 |
0.446 |
|
| 2019 |
Wang L, Shilatifard A. UTX Mutations in Human Cancer. Cancer Cell. 35: 168-176. PMID 30753822 DOI: 10.1016/J.Ccell.2019.01.001 |
0.397 |
|
| 2019 |
Chung CY, Berson A, Kennerdell JR, Sartoris A, Unger T, Porta S, Kim HJ, Smith ER, Shilatifard A, Van Deerlin V, Lee VM, Chen-Plotkin A, Bonini NM. Author Correction: Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity. Nature Communications. 10: 555. PMID 30696825 DOI: 10.1038/S41467-019-08562-X |
0.338 |
|
| 2019 |
Zhao Z, Wang L, Volk AG, Birch NW, Stoltz KL, Bartom ET, Marshall SA, Rendleman EJ, Nestler CM, Shilati J, Schiltz GE, Crispino JD, Shilatifard A. Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia. Genes & Development. 33: 61-74. PMID 30573454 DOI: 10.1101/Gad.319830.118 |
0.382 |
|
| 2019 |
Huang T, Piunti A, Ozark P, Barton E, Qi J, Hashizume R, Shilatifard A, Saratsis A. PDTM-31. INVESTIGATING THE EFFECT OF H3G34V MUTATION ON DISTINCT GENOMIC H3K36 METHYLATION PATTERNS IN PEDIATRIC GLIOMA Neuro-Oncology. 21: vi194-vi194. DOI: 10.1093/Neuonc/Noz175.807 |
0.355 |
|
| 2019 |
Huang T, Piunti A, Ozark P, Bartom E, Qi J, Hashizume R, Shilatifard A, Saratsis A. HGG-10. HISTONE H3G34V MUTATION IS SUFFICIENT TO DRIVE DISTINCT GENOMIC H3K36 METHYLATION PATTERNS IN PEDIATRIC GLIOMA Neuro-Oncology. 21: ii88-ii89. DOI: 10.1093/Neuonc/Noz036.104 |
0.316 |
|
| 2018 |
Huang T, Garcia R, Qi J, Lulla R, Horbinski C, Behdad A, Wadhwani N, Shilatifard A, James C, Saratsis A. Detection of histone H3 K27M mutation and post-translational modifications in pediatric diffuse midline glioma via tissue immunohistochemistry informs diagnosis and clinical outcomes. Oncotarget. 9: 37112-37124. PMID 30647848 DOI: 10.18632/Oncotarget.26430 |
0.321 |
|
| 2018 |
Volk A, Liang K, Suraneni P, Li X, Zhao J, Bulic M, Marshall S, Pulakanti K, Malinge S, Taub J, Ge Y, Rao S, Bartom E, Shilatifard A, Crispino JD. A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis. Cancer Cell. 34: 707-723.e7. PMID 30423293 DOI: 10.1016/J.Ccell.2018.10.004 |
0.447 |
|
| 2018 |
Wang L, Ozark PA, Smith ER, Zhao Z, Marshall SA, Rendleman EJ, Piunti A, Ryan C, Whelan AL, Helmin KA, Morgan MA, Zou L, Singer BD, Shilatifard A. TET2 coactivates gene expression through demethylation of enhancers. Science Advances. 4: eaau6986. PMID 30417100 DOI: 10.1126/Sciadv.Aau6986 |
0.378 |
|
| 2018 |
Chung CY, Berson A, Kennerdell JR, Sartoris A, Unger T, Porta S, Kim HJ, Smith ER, Shilatifard A, Van Deerlin V, Lee VM, Chen-Plotkin A, Bonini NM. Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity. Nature Communications. 9: 4406. PMID 30353006 DOI: 10.1038/S41467-018-06543-0 |
0.439 |
|
| 2018 |
Liang K, Smith ER, Aoi Y, Stoltz KL, Katagi H, Woodfin AR, Rendleman EJ, Marshall SA, Murray DC, Wang L, Ozark PA, Mishra RK, Hashizume R, Schiltz GE, Shilatifard A. Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy. Cell. 175: 766-779.e17. PMID 30340042 DOI: 10.1016/J.Cell.2018.09.027 |
0.474 |
|
| 2018 |
Haddad JF, Yang Y, Takahashi YH, Joshi M, Chaudhary N, Woodfin A, Benyoucef A, Yeung S, Brunzelle JS, Skiniotis G, Brand M, Shilatifard A, Couture JF. Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation. Structure (London, England : 1993). PMID 30270175 DOI: 10.1016/J.Str.2018.08.004 |
0.446 |
|
| 2018 |
Hong SH, Fang S, Lu BC, Nofsinger R, Kawakami Y, Castro GL, Yin Y, Lin C, Yu RT, Downes M, Izpisúa Belmonte JC, Shilatifard A, Evans RM. Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30254164 DOI: 10.1073/Pnas.1809480115 |
0.428 |
|
| 2018 |
Mas G, Blanco E, Ballaré C, Sansó M, Spill YG, Hu D, Aoi Y, Le Dily F, Shilatifard A, Marti-Renom MA, Di Croce L. Promoter bivalency favors an open chromatin architecture in embryonic stem cells. Nature Genetics. PMID 30224650 DOI: 10.1038/S41588-018-0218-5 |
0.417 |
|
| 2018 |
Qu Q, Takahashi YH, Yang Y, Hu H, Zhang Y, Brunzelle JS, Couture JF, Shilatifard A, Skiniotis G. Structure and Conformational Dynamics of a COMPASS Histone H3K4 Methyltransferase Complex. Cell. 174: 1117-1126.e12. PMID 30100186 DOI: 10.1016/J.Cell.2018.07.020 |
0.391 |
|
| 2018 |
Morgan MA, Shilatifard A. Epigenetic ConFUSION: SS18-SSX Fusion Rewires BAF Complex to Activate Bivalent Genes in Synovial Sarcoma. Cancer Cell. 33: 951-953. PMID 29894696 DOI: 10.1016/J.Ccell.2018.05.011 |
0.427 |
|
| 2018 |
Dhar SS, Zhao D, Lin T, Gu B, Pal K, Wu SJ, Alam H, Lv J, Yun K, Gopalakrishnan V, Flores ER, Northcott PA, Rajaram V, Li W, Shilatifard A, et al. MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes. Molecular Cell. PMID 29861161 DOI: 10.1016/J.Molcel.2018.04.028 |
0.36 |
|
| 2018 |
Wang L, Zhao Z, Ozark PA, Fantini D, Marshall SA, Rendleman EJ, Cozzolino KA, Louis N, He X, Morgan MA, Takahashi YH, Collings CK, Smith ER, Ntziachristos P, Savas JN, ... ... Shilatifard A, et al. Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy. Nature Medicine. PMID 29785026 DOI: 10.1038/S41591-018-0034-6 |
0.397 |
|
| 2018 |
Frankowski KJ, Wang C, Patnaik S, Schoenen FJ, Southall N, Li D, Teper Y, Sun W, Kandela I, Hu D, Dextras C, Knotts Z, Bian Y, Norton J, Titus S, ... ... Shilatifard A, et al. Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis. Science Translational Medicine. 10. PMID 29769289 DOI: 10.1126/Scitranslmed.Aap8307 |
0.32 |
|
| 2018 |
Rickels R, Shilatifard A. Enhancer Logic and Mechanics in Development and Disease. Trends in Cell Biology. PMID 29759817 DOI: 10.1016/J.Tcb.2018.04.003 |
0.348 |
|
| 2018 |
Chen FX, Smith ER, Shilatifard A. Born to run: control of transcription elongation by RNA polymerase II. Nature Reviews. Molecular Cell Biology. PMID 29740129 DOI: 10.1038/S41580-018-0010-5 |
0.501 |
|
| 2018 |
Cao K, Collings CK, Morgan MA, Marshall SA, Rendleman EJ, Ozark PA, Smith ER, Shilatifard A. An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells. Science Advances. 4: eaap8747. PMID 29404406 DOI: 10.1126/Sciadv.Aap8747 |
0.427 |
|
| 2018 |
Shilatifard A. Myoediting for Duchenne muscular dystrophy Science. 359: 530.1-530. DOI: 10.1126/Science.359.6375.530-A |
0.306 |
|
| 2018 |
Saratsis A, Huang T, Piunti A, A. Ozark P, Bartom E, Marshall S, Hashizume R, David James C, Shilatifard A. PDTM-39. HISTONE H3 MUTATION EFFECTS ON CHROMATIN STRUCTURE AND REGULATION OF GENE TRANSCRIPTION IN PEDIATRIC GLIOMA Neuro-Oncology. 20: vi212-vi212. DOI: 10.1093/Neuonc/Noy148.879 |
0.431 |
|
| 2018 |
Saratsis A, Piunti A, Huang T, Bartom E, Ozark P, Marshall S, Qi J, Hashizume R, Lulla R, David James C, Shilatifard A. DIPG-14. INTEGRATED DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) NEXT-GENERATION SEQUENCING REVEALS EPIGENETIC DYSREGULATION OF GENE EXPRESSION AND BROMODOMAIN INHIBITION AS A NOVEL THERAPEUTIC TARGET Neuro-Oncology. 20: i51-i51. DOI: 10.1093/Neuonc/Noy059.107 |
0.324 |
|
| 2017 |
Wang L, Collings CK, Zhao Z, Cozzolino KA, Ma Q, Liang K, Marshall SA, Sze CC, Hashizume R, Savas JN, Shilatifard A. A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism. Genes & Development. PMID 29138278 DOI: 10.1101/Gad.306092.117 |
0.391 |
|
| 2017 |
Morgan MAJ, Rickels RA, Collings CK, He X, Cao K, Herz HM, Cozzolino KA, Abshiru NA, Marshall SA, Rendleman EJ, Sze CC, Piunti A, Kelleher NL, Savas JN, Shilatifard A. A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation. Genes & Development. 31: 2003-2014. PMID 29089422 DOI: 10.1101/Gad.305201.117 |
0.475 |
|
| 2017 |
Rickels R, Herz HM, Sze CC, Cao K, Morgan MA, Collings CK, Gause M, Takahashi YH, Wang L, Rendleman EJ, Marshall SA, Krueger A, Bartom ET, Piunti A, Smith ER, ... ... Shilatifard A, et al. Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability. Nature Genetics. PMID 28967912 DOI: 10.1038/Ng.3965 |
0.446 |
|
| 2017 |
Sze CC, Cao K, Collings CK, Marshall SA, Rendleman EJ, Ozark PA, Chen FX, Morgan MA, Wang L, Shilatifard A. Histone H3K4 methylation-dependent and -independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation. Genes & Development. PMID 28939616 DOI: 10.1101/Gad.303768.117 |
0.397 |
|
| 2017 |
Chen FX, Xie P, Collings CK, Cao K, Aoi Y, Marshall SA, Rendleman EJ, Ugarenko M, Ozark PA, Zhang A, Shiekhattar R, Smith ER, Zhang MQ, Shilatifard A. PAF1 regulation of promoter-proximal pause release via enhancer activation. Science (New York, N.Y.). PMID 28860207 DOI: 10.1126/Science.Aan3269 |
0.449 |
|
| 2017 |
Ebmeier CC, Erickson B, Allen BL, Allen MA, Kim H, Fong N, Jacobsen JR, Liang K, Shilatifard A, Dowell RD, Old WM, Bentley DL, Taatjes DJ. Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications. Cell Reports. 20: 1173-1186. PMID 28768201 DOI: 10.1016/J.Celrep.2017.07.021 |
0.486 |
|
| 2017 |
Cao K, Collings CK, Marshall SA, Morgan MA, Rendleman EJ, Wang L, Sze CC, Sun T, Bartom ET, Shilatifard A. SET1A/COMPASS and shadow enhancers in the regulation of homeotic gene expression. Genes & Development. PMID 28487406 DOI: 10.1101/Gad.294744.116 |
0.455 |
|
| 2017 |
Vo BT, Li C, Morgan MA, Theurillat I, Finkelstein D, Wright S, Hyle J, Smith SM, Fan Y, Wang YD, Wu G, Orr BA, Northcott PA, Shilatifard A, Sherr CJ, et al. Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma. Cell Reports. 18: 2907-2917. PMID 28329683 DOI: 10.1016/J.Celrep.2017.02.073 |
0.345 |
|
| 2017 |
Piunti A, Hashizume R, Morgan MA, Bartom ET, Horbinski CM, Marshall SA, Rendleman EJ, Ma Q, Takahashi YH, Woodfin AR, Misharin AV, Abshiru NA, Lulla RR, Saratsis AM, Kelleher NL, ... ... Shilatifard A, et al. Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas. Nature Medicine. PMID 28263307 DOI: 10.1038/Nm.4296 |
0.439 |
|
| 2017 |
Hu D, Gao X, Cao K, Morgan MA, Mas G, Smith ER, Volk AG, Bartom ET, Crispino JD, Di Croce L, Shilatifard A. Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification. Molecular Cell. 65: 460-475.e6. PMID 28157506 DOI: 10.1016/J.Molcel.2017.01.013 |
0.467 |
|
| 2017 |
Liang K, Volk AG, Haug JS, Marshall SA, Woodfin AR, Bartom ET, Gilmore JM, Florens L, Washburn MP, Sullivan KD, Espinosa JM, Cannova J, Zhang J, Smith ER, Crispino JD, ... Shilatifard A, et al. Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia. Cell. PMID 28065413 DOI: 10.1016/J.Cell.2016.12.011 |
0.371 |
|
| 2016 |
Hu D, Shilatifard A. Epigenetics of hematopoiesis and hematological malignancies. Genes & Development. 30: 2021-2041. PMID 27798847 DOI: 10.1101/Gad.284109.116 |
0.371 |
|
| 2016 |
Swain A, Misulovin Z, Pherson M, Gause M, Mihindukulasuriya K, Rickels RA, Shilatifard A, Dorsett D. Drosophila TDP-43 RNA-Binding Protein Facilitates Association of Sister Chromatid Cohesion Proteins with Genes, Enhancers and Polycomb Response Elements. Plos Genetics. 12: e1006331. PMID 27662615 DOI: 10.1371/Journal.Pgen.1006331 |
0.442 |
|
| 2016 |
Sze CC, Shilatifard A. MLL3/MLL4/COMPASS Family on Epigenetic Regulation of Enhancer Function and Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 27638352 DOI: 10.1101/Cshperspect.A026427 |
0.405 |
|
| 2016 |
Rickels R, Hu D, Collings CK, Woodfin AR, Piunti A, Mohan M, Herz HM, Kvon E, Shilatifard A. An Evolutionary Conserved Epigenetic Mark of Polycomb Response Elements Implemented by Trx/MLL/COMPASS. Molecular Cell. 63: 318-28. PMID 27447986 DOI: 10.1016/J.Molcel.2016.06.018 |
0.451 |
|
| 2016 |
D'Urso A, Takahashi YH, Xiong B, Marone J, Coukos R, Randise-Hinchliff C, Wang JP, Shilatifard A, Brickner JH. Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory. Elife. 5. PMID 27336723 DOI: 10.7554/Elife.16691 |
0.439 |
|
| 2016 |
Piunti A, Shilatifard A. Epigenetic balance of gene expression by Polycomb and COMPASS families. Science (New York, N.Y.). 352: aad9780. PMID 27257261 DOI: 10.1126/Science.Aad9780 |
0.478 |
|
| 2016 |
Wang Q, Trevino LS, Wong RL, Medvedovic M, Chen J, Ho SM, Shen J, Foulds CE, Coarfa C, O'Malley BW, Shilatifard A, Walker CL. Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk. Molecular Endocrinology (Baltimore, Md.). 30: 856-71. PMID 27219490 DOI: 10.1210/Me.2015-1310 |
0.309 |
|
| 2016 |
Luo Z, Lin C, Woodfin AR, Bartom ET, Gao X, Smith ER, Shilatifard A. Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity. Genes & Development. 30: 92-101. PMID 26728555 DOI: 10.1101/Gad.270413.115 |
0.459 |
|
| 2016 |
D'Urso A, Takahashi Y, Xiong B, Marone J, Coukos R, Randise-Hinchliff C, Wang J, Shilatifard A, Brickner JH. Author response: Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory Elife. DOI: 10.7554/Elife.16691.020 |
0.338 |
|
| 2016 |
Saratsis A, Huang T, Piunti A, Hashizume R, Bartom E, Tomita T, James CD, Shilatifard A. PDTB-14. INVESTIGATING HISTONE H3 POST-TRANSLATIONAL MODIFICATIONS USING PARAFFIN-EMBEDDED PEDIATRIC GLIOMA TISSUE SAMPLES Neuro-Oncology. 18: vi152-vi153. DOI: 10.1093/Neuonc/Now212.634 |
0.313 |
|
| 2016 |
Ma Q, Plunti A, Saratsis A, Lulla R, Fangusaro JR, Horbinski C, Goldman S, James CD, Shilatifard A, Hashizume R. PDTB-10. INHIBITION OF RADIATION-INDUCED DNA DAMAGE REPAIR MEDIATED CHROMATIN MODIFICATION BY HISTONE H3 DEMETHYLASE INHIBITOR IN PEDIATRIC BRAINSTEM GLIOMA Neuro-Oncology. 18: vi151-vi152. DOI: 10.1093/Neuonc/Now212.630 |
0.313 |
|
| 2015 |
Liang K, Woodfin AR, Slaughter BD, Unruh JR, Box AC, Rickels RA, Gao X, Haug JS, Jaspersen SL, Shilatifard A. Mitotic Transcriptional Activation: Clearance of Actively Engaged Pol II via Transcriptional Elongation Control in Mitosis. Molecular Cell. 60: 435-45. PMID 26527278 DOI: 10.1016/J.Molcel.2015.09.021 |
0.522 |
|
| 2015 |
Ortega-Molina A, Boss IW, Canela A, Pan H, Jiang Y, Zhao C, Jiang M, Hu D, Agirre X, Niesvizky I, Lee JE, Chen HT, Ennishi D, Scott DW, Mottok A, ... ... Shilatifard A, et al. The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development. Nature Medicine. PMID 26366710 DOI: 10.1038/Nm.3943 |
0.39 |
|
| 2015 |
Zhu J, Sammons MA, Donahue G, Dou Z, Vedadi M, Getlik M, Barsyte-Lovejoy D, Al-awar R, Katona BW, Shilatifard A, Huang J, Hua X, Arrowsmith CH, Berger SL. Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth. Nature. 525: 206-11. PMID 26331536 DOI: 10.1038/Nature15251 |
0.353 |
|
| 2015 |
Chen FX, Woodfin AR, Gardini A, Rickels RA, Marshall SA, Smith ER, Shiekhattar R, Shilatifard A. PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II. Cell. PMID 26279188 DOI: 10.1016/J.Cell.2015.07.042 |
0.498 |
|
| 2015 |
De Kumar B, Parrish ME, Slaughter BD, Unruh JR, Gogol M, Seidel C, Paulson A, Li H, Gaudenz K, Peak A, McDowell W, Fleharty B, Ahn Y, Lin C, Smith E, ... Shilatifard A, et al. Analysis of dynamic changes in retinoid-induced transcription and epigenetic profiles of murine Hox clusters in ES cells. Genome Research. PMID 26025802 DOI: 10.1101/Gr.184978.114 |
0.456 |
|
| 2015 |
Fowler T, Ghatak P, Price DH, Conaway R, Conaway J, Chiang CM, Bradner JE, Shilatifard A, Roy AL. Correction: Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells. Plos One. 10: e0126328. PMID 25902070 DOI: 10.1371/Journal.Pone.0126328 |
0.553 |
|
| 2015 |
Luo Z, Gao X, Lin C, Smith ER, Marshall SA, Swanson SK, Florens L, Washburn MP, Shilatifard A. Zic2 is an enhancer-binding factor required for embryonic stem cell specification. Molecular Cell. 57: 685-94. PMID 25699711 DOI: 10.1016/J.Molcel.2015.01.007 |
0.444 |
|
| 2015 |
Morgan MA, Shilatifard A. Chromatin signatures of cancer. Genes & Development. 29: 238-49. PMID 25644600 DOI: 10.1101/Gad.255182.114 |
0.443 |
|
| 2015 |
Zhang P, Chaturvedi CP, Tremblay V, Cramet M, Brunzelle JS, Skiniotis G, Brand M, Shilatifard A, Couture JF. A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation. Genes & Development. 29: 123-8. PMID 25593305 DOI: 10.1101/Gad.254870.114 |
0.429 |
|
| 2015 |
Chen F, Gao X, Shilatifard A. Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide. Genes & Development. 29: 39-47. PMID 25561494 DOI: 10.1101/Gad.246173.114 |
0.477 |
|
| 2015 |
Liang K, Gao X, Gilmore JM, Florens L, Washburn MP, Smith E, Shilatifard A. Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing. Molecular and Cellular Biology. 35: 928-38. PMID 25561469 DOI: 10.1128/Mcb.01426-14 |
0.424 |
|
| 2015 |
Ortega-Molina A, Boss I, Pan H, Jiang Y, Hu D, Gao X, Shaknovich R, Shilatifard A, Melnick AM, Wendel H. Abstract LB-064: Characterization of the tumor suppressor function of the lysine-specific methyltransferase KMT2D in follicular lymphoma Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-064 |
0.404 |
|
| 2015 |
Shilatifard A. Amalgamated regulators of gene expression Science. 349: 1066-1068. DOI: 10.1126/Science.349.6252.1066-R |
0.356 |
|
| 2015 |
Baylin SB, Roberts C, Shilatifard A. Part 4: Targeting cancer pathways: The epigenetics question Science. 349. DOI: 10.1126/Science.349.6248.656-C |
0.3 |
|
| 2014 |
Tremblay V, Zhang P, Chaturvedi CP, Thornton J, Brunzelle JS, Skiniotis G, Shilatifard A, Brand M, Couture JF. Molecular basis for DPY-30 association to COMPASS-like and NURF complexes. Structure (London, England : 1993). 22: 1821-30. PMID 25456412 DOI: 10.1016/J.Str.2014.10.002 |
0.419 |
|
| 2014 |
Gardini A, Baillat D, Cesaroni M, Hu D, Marinis JM, Wagner EJ, Lazar MA, Shilatifard A, Shiekhattar R. Integrator regulates transcriptional initiation and pause release following activation. Molecular Cell. 56: 128-39. PMID 25201415 DOI: 10.1016/J.Molcel.2014.08.004 |
0.465 |
|
| 2014 |
Herz HM, Morgan M, Gao X, Jackson J, Rickels R, Swanson SK, Florens L, Washburn MP, Eissenberg JC, Shilatifard A. Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling. Science (New York, N.Y.). 345: 1065-70. PMID 25170156 DOI: 10.1126/Science.1255104 |
0.419 |
|
| 2014 |
Cao K, Shilatifard A. Inhibit globally, act locally: CDK7 inhibitors in cancer therapy. Cancer Cell. 26: 158-9. PMID 25117707 DOI: 10.1016/J.Ccr.2014.07.020 |
0.325 |
|
| 2014 |
Cheng J, Blum R, Bowman C, Hu D, Shilatifard A, Shen S, Dynlacht BD. A role for H3K4 monomethylation in gene repression and partitioning of chromatin readers. Molecular Cell. 53: 979-92. PMID 24656132 DOI: 10.1016/J.Molcel.2014.02.032 |
0.449 |
|
| 2014 |
Herz HM, Hu D, Shilatifard A. Enhancer malfunction in cancer. Molecular Cell. 53: 859-66. PMID 24656127 DOI: 10.1016/J.Molcel.2014.02.033 |
0.361 |
|
| 2014 |
Smith E, Shilatifard A. Enhancer biology and enhanceropathies. Nature Structural & Molecular Biology. 21: 210-9. PMID 24599251 DOI: 10.1038/Nsmb.2784 |
0.523 |
|
| 2014 |
Fowler T, Ghatak P, Price DH, Conaway R, Conaway J, Chiang CM, Bradner JE, Shilatifard A, Roy AL. Regulation of MYC expression and differential JQ1 sensitivity in cancer cells. Plos One. 9: e87003. PMID 24466310 DOI: 10.1371/Journal.Pone.0087003 |
0.614 |
|
| 2014 |
Thornton JL, Westfield GH, Takahashi YH, Cook M, Gao X, Woodfin AR, Lee JS, Morgan MA, Jackson J, Smith ER, Couture JF, Skiniotis G, Shilatifard A. Context dependency of Set1/COMPASS-mediated histone H3 Lys4 trimethylation. Genes & Development. 28: 115-20. PMID 24402317 DOI: 10.1101/Gad.232215.113 |
0.404 |
|
| 2013 |
Herz HM, Garruss A, Shilatifard A. SET for life: biochemical activities and biological functions of SET domain-containing proteins. Trends in Biochemical Sciences. 38: 621-39. PMID 24148750 DOI: 10.1016/J.Tibs.2013.09.004 |
0.404 |
|
| 2013 |
Hu D, Gao X, Morgan MA, Herz HM, Smith ER, Shilatifard A. The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers. Molecular and Cellular Biology. 33: 4745-54. PMID 24081332 DOI: 10.1128/Mcb.01181-13 |
0.449 |
|
| 2013 |
Hu D, Garruss AS, Gao X, Morgan MA, Cook M, Smith ER, Shilatifard A. The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells. Nature Structural & Molecular Biology. 20: 1093-7. PMID 23934151 DOI: 10.1038/Nsmb.2653 |
0.403 |
|
| 2013 |
Hu D, Smith ER, Garruss AS, Mohaghegh N, Varberg JM, Lin C, Jackson J, Gao X, Saraf A, Florens L, Washburn MP, Eissenberg JC, Shilatifard A. The little elongation complex functions at initiation and elongation phases of snRNA gene transcription. Molecular Cell. 51: 493-505. PMID 23932780 DOI: 10.1016/J.Molcel.2013.07.003 |
0.529 |
|
| 2013 |
Rickels R, Shilatifard A. A histone modifier's ill-gotten copy gains. Cell. 154: 477-9. PMID 23911314 DOI: 10.1016/J.Cell.2013.07.010 |
0.345 |
|
| 2013 |
Smith E, Shilatifard A. Transcriptional elongation checkpoint control in development and disease. Genes & Development. 27: 1079-88. PMID 23699407 DOI: 10.1101/Gad.215137.113 |
0.469 |
|
| 2013 |
Morgan MA, Shilatifard A. Medicine. (Poly)combing the pediatric cancer genome for answers. Science (New York, N.Y.). 340: 823-4. PMID 23687038 DOI: 10.1126/Science.1239223 |
0.362 |
|
| 2013 |
Morgan MA, Shilatifard A. Drosophila SETs its sights on cancer: Trr/MLL3/4 COMPASS-like complexes in development and disease. Molecular and Cellular Biology. 33: 1698-701. PMID 23459940 DOI: 10.1128/Mcb.00203-13 |
0.474 |
|
| 2013 |
Tarayrah L, Herz HM, Shilatifard A, Chen X. Histone demethylase dUTX antagonizes JAK-STAT signaling to maintain proper gene expression and architecture of the Drosophila testis niche. Development (Cambridge, England). 140: 1014-23. PMID 23364332 DOI: 10.1242/Dev.089433 |
0.392 |
|
| 2013 |
Lin C, Garruss AS, Luo Z, Guo F, Shilatifard A. The RNA Pol II elongation factor Ell3 marks enhancers in ES cells and primes future gene activation. Cell. 152: 144-56. PMID 23273992 DOI: 10.1016/J.Cell.2012.12.015 |
0.517 |
|
| 2013 |
Shilatifard A. Abstract IA5: Chromosomal translocations and transcriptional elongation control in epigenetics and cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Ia5 |
0.53 |
|
| 2012 |
Herz HM, Mohan M, Garruss AS, Liang K, Takahashi YH, Mickey K, Voets O, Verrijzer CP, Shilatifard A. Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4. Genes & Development. 26: 2604-20. PMID 23166019 DOI: 10.1101/Gad.201327.112 |
0.472 |
|
| 2012 |
Luo Z, Lin C, Shilatifard A. The super elongation complex (SEC) family in transcriptional control. Nature Reviews. Molecular Cell Biology. 13: 543-7. PMID 22895430 DOI: 10.1038/Nrm3417 |
0.514 |
|
| 2012 |
Shilatifard A. The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis. Annual Review of Biochemistry. 81: 65-95. PMID 22663077 DOI: 10.1146/Annurev-Biochem-051710-134100 |
0.432 |
|
| 2012 |
Lee JS, Garrett AS, Yen K, Takahashi YH, Hu D, Jackson J, Seidel C, Pugh BF, Shilatifard A. Codependency of H2B monoubiquitination and nucleosome reassembly on Chd1. Genes & Development. 26: 914-9. PMID 22549955 DOI: 10.1101/Gad.186841.112 |
0.427 |
|
| 2012 |
Luo Z, Lin C, Guest E, Garrett AS, Mohaghegh N, Swanson S, Marshall S, Florens L, Washburn MP, Shilatifard A. The super elongation complex family of RNA polymerase II elongation factors: gene target specificity and transcriptional output. Molecular and Cellular Biology. 32: 2608-17. PMID 22547686 DOI: 10.1128/Mcb.00182-12 |
0.497 |
|
| 2012 |
Mohan M, Herz HM, Shilatifard A. SnapShot: Histone lysine methylase complexes. Cell. 149: 498-498.e1. PMID 22500810 DOI: 10.1016/J.Cell.2012.03.025 |
0.419 |
|
| 2012 |
Herz HM, Mohan M, Garrett AS, Miller C, Casto D, Zhang Y, Seidel C, Haug JS, Florens L, Washburn MP, Yamaguchi M, Shiekhattar R, Shilatifard A. Polycomb repressive complex 2-dependent and -independent functions of Jarid2 in transcriptional regulation in Drosophila. Molecular and Cellular Biology. 32: 1683-93. PMID 22354997 DOI: 10.1128/Mcb.06503-11 |
0.5 |
|
| 2011 |
Smith ER, Lin C, Garrett AS, Thornton J, Mohaghegh N, Hu D, Jackson J, Saraf A, Swanson SK, Seidel C, Florens L, Washburn MP, Eissenberg JC, Shilatifard A. The little elongation complex regulates small nuclear RNA transcription. Molecular Cell. 44: 954-65. PMID 22195968 DOI: 10.1016/J.Molcel.2011.12.008 |
0.517 |
|
| 2011 |
Takahashi YH, Westfield GH, Oleskie AN, Trievel RC, Shilatifard A, Skiniotis G. Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human. Proceedings of the National Academy of Sciences of the United States of America. 108: 20526-31. PMID 22158900 DOI: 10.1073/Pnas.1109360108 |
0.415 |
|
| 2011 |
Schulze JM, Hentrich T, Nakanishi S, Gupta A, Emberly E, Shilatifard A, Kobor MS. Splitting the task: Ubp8 and Ubp10 deubiquitinate different cellular pools of H2BK123. Genes & Development. 25: 2242-7. PMID 22056669 DOI: 10.1101/Gad.177220.111 |
0.375 |
|
| 2011 |
Mohan M, Herz HM, Smith ER, Zhang Y, Jackson J, Washburn MP, Florens L, Eissenberg JC, Shilatifard A. The COMPASS family of H3K4 methylases in Drosophila. Molecular and Cellular Biology. 31: 4310-8. PMID 21875999 DOI: 10.1128/Mcb.06092-11 |
0.433 |
|
| 2011 |
Lin C, Garrett AS, De Kumar B, Smith ER, Gogol M, Seidel C, Krumlauf R, Shilatifard A. Dynamic transcriptional events in embryonic stem cells mediated by the super elongation complex (SEC). Genes & Development. 25: 1486-98. PMID 21764852 DOI: 10.1101/Gad.2059211 |
0.499 |
|
| 2011 |
Henikoff S, Shilatifard A. Histone modification: cause or cog? Trends in Genetics : Tig. 27: 389-96. PMID 21764166 DOI: 10.1016/J.Tig.2011.06.006 |
0.417 |
|
| 2011 |
Takahashi H, Parmely TJ, Sato S, Tomomori-Sato C, Banks CA, Kong SE, Szutorisz H, Swanson SK, Martin-Brown S, Washburn MP, Florens L, Seidel CW, Lin C, Smith ER, Shilatifard A, et al. Human mediator subunit MED26 functions as a docking site for transcription elongation factors. Cell. 146: 92-104. PMID 21729782 DOI: 10.1016/J.Cell.2011.06.005 |
0.788 |
|
| 2011 |
Takahashi YH, Schulze JM, Jackson J, Hentrich T, Seidel C, Jaspersen SL, Kobor MS, Shilatifard A. Dot1 and histone H3K79 methylation in natural telomeric and HM silencing. Molecular Cell. 42: 118-26. PMID 21474073 DOI: 10.1016/J.Molcel.2011.03.006 |
0.397 |
|
| 2011 |
Smith E, Lin C, Shilatifard A. The super elongation complex (SEC) and MLL in development and disease. Genes & Development. 25: 661-72. PMID 21460034 DOI: 10.1101/Gad.2015411 |
0.495 |
|
| 2011 |
Yu Y, Srinivasan M, Nakanishi S, Leatherwood J, Shilatifard A, Sternglanz R. A conserved patch near the C terminus of histone H4 is required for genome stability in budding yeast. Molecular and Cellular Biology. 31: 2311-25. PMID 21444721 DOI: 10.1128/Mcb.01432-10 |
0.355 |
|
| 2011 |
Shilatifard A, Verrijzer P. Chromosomes and gene expression mechanisms: peeling away the many layers of transcriptional control. Current Opinion in Genetics & Development. 21: 121-3. PMID 21377351 DOI: 10.1016/J.Gde.2011.02.004 |
0.346 |
|
| 2010 |
Smith E, Shilatifard A. The chromatin signaling pathway: diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes. Molecular Cell. 40: 689-701. PMID 21145479 DOI: 10.1016/J.Molcel.2010.11.031 |
0.407 |
|
| 2010 |
Mohan M, Lin C, Guest E, Shilatifard A. Licensed to elongate: a molecular mechanism for MLL-based leukaemogenesis. Nature Reviews. Cancer. 10: 721-8. PMID 20844554 DOI: 10.1038/Nrc2915 |
0.505 |
|
| 2010 |
Lee JS, Smith E, Shilatifard A. The language of histone crosstalk. Cell. 142: 682-5. PMID 20813257 DOI: 10.1016/J.Cell.2010.08.011 |
0.363 |
|
| 2010 |
Herz HM, Shilatifard A. The JARID2-PRC2 duality. Genes & Development. 24: 857-61. PMID 20439426 DOI: 10.1101/Gad.1921610 |
0.475 |
|
| 2010 |
Herz HM, Madden LD, Chen Z, Bolduc C, Buff E, Gupta R, Davuluri R, Shilatifard A, Hariharan IK, Bergmann A. The H3K27me3 demethylase dUTX is a suppressor of Notch- and Rb-dependent tumors in Drosophila. Molecular and Cellular Biology. 30: 2485-97. PMID 20212086 DOI: 10.1128/Mcb.01633-09 |
0.355 |
|
| 2010 |
Mohan M, Herz HM, Takahashi YH, Lin C, Lai KC, Zhang Y, Washburn MP, Florens L, Shilatifard A. Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom). Genes & Development. 24: 574-89. PMID 20203130 DOI: 10.1101/Gad.1898410 |
0.439 |
|
| 2010 |
Lin C, Smith ER, Takahashi H, Lai KC, Martin-Brown S, Florens L, Washburn MP, Conaway JW, Conaway RC, Shilatifard A. AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Molecular Cell. 37: 429-37. PMID 20159561 DOI: 10.1016/J.Molcel.2010.01.026 |
0.782 |
|
| 2010 |
Takahashi YH, Shilatifard A. Structural basis for H3K4 trimethylation by yeast Set1/COMPASS. Advances in Enzyme Regulation. 50: 104-10. PMID 20005892 DOI: 10.1016/J.Advenzreg.2009.12.005 |
0.375 |
|
| 2010 |
Eissenberg JC, Shilatifard A. Histone H3 lysine 4 (H3K4) methylation in development and differentiation. Developmental Biology. 339: 240-9. PMID 19703438 DOI: 10.1016/J.Ydbio.2009.08.017 |
0.432 |
|
| 2009 |
Camahort R, Shivaraju M, Mattingly M, Li B, Nakanishi S, Zhu D, Shilatifard A, Workman JL, Gerton JL. Cse4 is part of an octameric nucleosome in budding yeast. Molecular Cell. 35: 794-805. PMID 19782029 DOI: 10.1016/J.Molcel.2009.07.022 |
0.402 |
|
| 2009 |
Herz HM, Nakanishi S, Shilatifard A. The curious case of bivalent marks. Developmental Cell. 17: 301-3. PMID 19758552 DOI: 10.1016/J.Devcel.2009.08.014 |
0.374 |
|
| 2009 |
Wang P, Lin C, Smith ER, Guo H, Sanderson BW, Wu M, Gogol M, Alexander T, Seidel C, Wiedemann LM, Ge K, Krumlauf R, Shilatifard A. Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II. Molecular and Cellular Biology. 29: 6074-85. PMID 19703992 DOI: 10.1128/Mcb.00924-09 |
0.496 |
|
| 2009 |
Schulze JM, Jackson J, Nakanishi S, Gardner JM, Hentrich T, Haug J, Johnston M, Jaspersen SL, Kobor MS, Shilatifard A. Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation. Molecular Cell. 35: 626-41. PMID 19682934 DOI: 10.1016/J.Molcel.2009.07.017 |
0.454 |
|
| 2009 |
Nakanishi S, Lee JS, Gardner KE, Gardner JM, Takahashi YH, Chandrasekharan MB, Sun ZW, Osley MA, Strahl BD, Jaspersen SL, Shilatifard A. Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1. The Journal of Cell Biology. 186: 371-7. PMID 19667127 DOI: 10.1083/Jcb.200906005 |
0.418 |
|
| 2009 |
Trievel RC, Shilatifard A. WDR5, a complexed protein. Nature Structural & Molecular Biology. 16: 678-80. PMID 19578375 DOI: 10.1038/Nsmb0709-678 |
0.449 |
|
| 2009 |
Jackson J, Shilatifard A. Global proteomic analysis of Saccharomyces cerevisiae identifies molecular pathways of histone modifications. Methods in Molecular Biology (Clifton, N.J.). 548: 175-86. PMID 19521825 DOI: 10.1007/978-1-59745-540-4_10 |
0.424 |
|
| 2009 |
Dang W, Steffen KK, Perry R, Dorsey JA, Johnson FB, Shilatifard A, Kaeberlein M, Kennedy BK, Berger SL. Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature. 459: 802-7. PMID 19516333 DOI: 10.1038/Nature08085 |
0.448 |
|
| 2009 |
Kim J, Guermah M, McGinty RK, Lee JS, Tang Z, Milne TA, Shilatifard A, Muir TW, Roeder RG. RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell. 137: 459-71. PMID 19410543 DOI: 10.1016/J.Cell.2009.02.027 |
0.49 |
|
| 2009 |
Takahashi YH, Lee JS, Swanson SK, Saraf A, Florens L, Washburn MP, Trievel RC, Shilatifard A. Regulation of H3K4 trimethylation via Cps40 (Spp1) of COMPASS is monoubiquitination independent: implication for a Phe/Tyr switch by the catalytic domain of Set1. Molecular and Cellular Biology. 29: 3478-86. PMID 19398585 DOI: 10.1128/Mcb.00013-09 |
0.416 |
|
| 2009 |
Berger SL, Kouzarides T, Shiekhattar R, Shilatifard A. An operational definition of epigenetics. Genes & Development. 23: 781-3. PMID 19339683 DOI: 10.1101/Gad.1787609 |
0.345 |
|
| 2009 |
Li B, Jackson J, Simon MD, Fleharty B, Gogol M, Seidel C, Workman JL, Shilatifard A. Histone H3 lysine 36 dimethylation (H3K36me2) is sufficient to recruit the Rpd3s histone deacetylase complex and to repress spurious transcription. The Journal of Biological Chemistry. 284: 7970-6. PMID 19155214 DOI: 10.1074/Jbc.M808220200 |
0.434 |
|
| 2009 |
Smith E, Shilatifard A. Developmental biology. Histone cross-talk in stem cells. Science (New York, N.Y.). 323: 221-2. PMID 19131622 DOI: 10.1126/Science.1168660 |
0.367 |
|
| 2008 |
Wu M, Wang PF, Lee JS, Martin-Brown S, Florens L, Washburn M, Shilatifard A. Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS. Molecular and Cellular Biology. 28: 7337-44. PMID 18838538 DOI: 10.1128/Mcb.00976-08 |
0.418 |
|
| 2008 |
Nakanishi S, Sanderson BW, Delventhal KM, Bradford WD, Staehling-Hampton K, Shilatifard A. A comprehensive library of histone mutants identifies nucleosomal residues required for H3K4 methylation. Nature Structural & Molecular Biology. 15: 881-8. PMID 18622391 DOI: 10.1038/Nsmb.1454 |
0.389 |
|
| 2008 |
Smith ER, Winter B, Eissenberg JC, Shilatifard A. Regulation of the transcriptional activity of poised RNA polymerase II by the elongation factor ELL. Proceedings of the National Academy of Sciences of the United States of America. 105: 8575-9. PMID 18562276 DOI: 10.1073/Pnas.0804379105 |
0.513 |
|
| 2008 |
Shilatifard A. Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation. Current Opinion in Cell Biology. 20: 341-8. PMID 18508253 DOI: 10.1016/J.Ceb.2008.03.019 |
0.419 |
|
| 2008 |
Wang P, Bowl MR, Bender S, Peng J, Farber L, Chen J, Ali A, Zhang Z, Alberts AS, Thakker RV, Shilatifard A, Williams BO, Teh BT. Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice. Molecular and Cellular Biology. 28: 2930-40. PMID 18212049 DOI: 10.1128/Mcb.00654-07 |
0.391 |
|
| 2008 |
Smith ER, Lee MG, Winter B, Droz NM, Eissenberg JC, Shiekhattar R, Shilatifard A. Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II. Molecular and Cellular Biology. 28: 1041-6. PMID 18039863 DOI: 10.1128/Mcb.01504-07 |
0.513 |
|
| 2007 |
Lee JS, Shukla A, Schneider J, Swanson SK, Washburn MP, Florens L, Bhaumik SR, Shilatifard A. Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS. Cell. 131: 1084-96. PMID 18083099 DOI: 10.1016/J.Cell.2007.09.046 |
0.426 |
|
| 2007 |
Bhaumik SR, Smith E, Shilatifard A. Covalent modifications of histones during development and disease pathogenesis. Nature Structural & Molecular Biology. 14: 1008-16. PMID 17984963 DOI: 10.1038/Nsmb1337 |
0.415 |
|
| 2007 |
Ingvarsdottir K, Edwards C, Lee MG, Lee JS, Schultz DC, Shilatifard A, Shiekhattar R, Berger SL. Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae. Molecular and Cellular Biology. 27: 7856-64. PMID 17875926 DOI: 10.1128/Mcb.00801-07 |
0.436 |
|
| 2007 |
Smith E, Shilatifard A. The A, B, Gs of silencing. Genes & Development. 21: 1141-4. PMID 17504932 DOI: 10.1101/Gad.1559407 |
0.423 |
|
| 2007 |
Eissenberg JC, Lee MG, Schneider J, Ilvarsonn A, Shiekhattar R, Shilatifard A. The trithorax-group gene in Drosophila little imaginal discs encodes a trimethylated histone H3 Lys4 demethylase. Nature Structural & Molecular Biology. 14: 344-6. PMID 17351630 DOI: 10.1038/Nsmb1217 |
0.443 |
|
| 2007 |
Lee JS, Shilatifard A. A site to remember: H3K36 methylation a mark for histone deacetylation. Mutation Research. 618: 130-4. PMID 17346757 DOI: 10.1016/J.Mrfmmm.2006.08.014 |
0.511 |
|
| 2007 |
Lee MG, Norman J, Shilatifard A, Shiekhattar R. Physical and functional association of a trimethyl H3K4 demethylase and Ring6a/MBLR, a polycomb-like protein. Cell. 128: 877-87. PMID 17320162 DOI: 10.1016/J.Cell.2007.02.004 |
0.523 |
|
| 2007 |
Wood A, Shukla A, Schneider J, Lee JS, Stanton JD, Dzuiba T, Swanson SK, Florens L, Washburn MP, Wyrick J, Bhaumik SR, Shilatifard A. Ctk complex-mediated regulation of histone methylation by COMPASS. Molecular and Cellular Biology. 27: 709-20. PMID 17088385 DOI: 10.1128/Mcb.01627-06 |
0.485 |
|
| 2007 |
Eissenberg JC, Shilatifard A, Dorokhov N, Michener DE. Cdk9 is an essential kinase in Drosophila that is required for heat shock gene expression, histone methylation and elongation factor recruitment. Molecular Genetics and Genomics : Mgg. 277: 101-14. PMID 17001490 DOI: 10.1007/S00438-006-0164-2 |
0.503 |
|
| 2006 |
Schneider J, Shilatifard A. Histone demethylation by hydroxylation: chemistry in action. Acs Chemical Biology. 1: 75-81. PMID 17163647 DOI: 10.1021/Cb600030B |
0.388 |
|
| 2006 |
Schneider J, Bajwa P, Johnson FC, Bhaumik SR, Shilatifard A. Rtt109 is required for proper H3K56 acetylation: a chromatin mark associated with the elongating RNA polymerase II. The Journal of Biological Chemistry. 281: 37270-4. PMID 17046836 DOI: 10.1074/Jbc.C600265200 |
0.499 |
|
| 2006 |
Wendt KD, Shilatifard A. Packing for the germy: the role of histone H4 Ser1 phosphorylation in chromatin compaction and germ cell development. Genes & Development. 20: 2487-91. PMID 16980578 DOI: 10.1101/Gad.1477706 |
0.441 |
|
| 2006 |
Steward MM, Lee JS, O'Donovan A, Wyatt M, Bernstein BE, Shilatifard A. Molecular regulation of H3K4 trimethylation by ASH2L, a shared subunit of MLL complexes. Nature Structural & Molecular Biology. 13: 852-4. PMID 16892064 DOI: 10.1038/Nsmb1131 |
0.423 |
|
| 2006 |
Tenney K, Gerber M, Ilvarsonn A, Schneider J, Gause M, Dorsett D, Eissenberg JC, Shilatifard A. Drosophila Rtf1 functions in histone methylation, gene expression, and Notch signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 11970-4. PMID 16882721 DOI: 10.1073/Pnas.0603620103 |
0.772 |
|
| 2006 |
Shilatifard A. Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annual Review of Biochemistry. 75: 243-69. PMID 16756492 DOI: 10.1146/Annurev.Biochem.75.103004.142422 |
0.459 |
|
| 2006 |
Wood A, Shilatifard A. Bur1/Bur2 and the Ctk complex in yeast: the split personality of mammalian P-TEFb. Cell Cycle (Georgetown, Tex.). 5: 1066-8. PMID 16721054 DOI: 10.4161/Cc.5.10.2769 |
0.495 |
|
| 2006 |
Pavri R, Zhu B, Li G, Trojer P, Mandal S, Shilatifard A, Reinberg D. Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. Cell. 125: 703-17. PMID 16713563 DOI: 10.1016/J.Cell.2006.04.029 |
0.529 |
|
| 2006 |
Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, PeregrÃn-Alvarez JM, Shales M, Zhang X, Davey M, ... ... Shilatifard A, et al. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 440: 637-43. PMID 16554755 DOI: 10.1038/Nature04670 |
0.311 |
|
| 2006 |
Wood A, Shilatifard A. Transcriptional blackjack with p21. Genes & Development. 20: 643-7. PMID 16543217 DOI: 10.1101/Gad.1414506 |
0.456 |
|
| 2006 |
Eissenberg JC, Shilatifard A. Leaving a mark: the many footprints of the elongating RNA polymerase II. Current Opinion in Genetics & Development. 16: 184-90. PMID 16503129 DOI: 10.1016/J.Gde.2006.02.004 |
0.527 |
|
| 2006 |
SHILATIFARD A. Chromatin and transcriptional regulation Methods. 40: 295-295. DOI: 10.1016/J.Ymeth.2006.10.003 |
0.454 |
|
| 2005 |
Wood A, Schneider J, Dover J, Johnston M, Shilatifard A. The Bur1/Bur2 complex is required for histone H2B monoubiquitination by Rad6/Bre1 and histone methylation by COMPASS. Molecular Cell. 20: 589-99. PMID 16307922 DOI: 10.1016/J.Molcel.2005.09.010 |
0.454 |
|
| 2005 |
Baillat D, Hakimi MA, Näär AM, Shilatifard A, Cooch N, Shiekhattar R. Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. Cell. 123: 265-76. PMID 16239144 DOI: 10.1016/J.Cell.2005.08.019 |
0.479 |
|
| 2005 |
Wynder C, Hakimi MA, Epstein JA, Shilatifard A, Shiekhattar R. Recruitment of MLL by HMG-domain protein iBRAF promotes neural differentiation. Nature Cell Biology. 7: 1113-7. PMID 16227968 DOI: 10.1038/Ncb1312 |
0.419 |
|
| 2005 |
Wood A, Shilatifard A. Guided by COMPASS on a journey through chromosome segregation. Nature Structural & Molecular Biology. 12: 839-40. PMID 16205707 DOI: 10.1038/Nsmb1005-839 |
0.351 |
|
| 2005 |
Schneider J, Wood A, Lee JS, Schuster R, Dueker J, Maguire C, Swanson SK, Florens L, Washburn MP, Shilatifard A. Molecular regulation of histone H3 trimethylation by COMPASS and the regulation of gene expression. Molecular Cell. 19: 849-56. PMID 16168379 DOI: 10.1016/J.Molcel.2005.07.024 |
0.455 |
|
| 2005 |
Gerber MA, Shilatifard A, Eissenberg JC. Mutational analysis of an RNA polymerase II elongation factor in Drosophila melanogaster. Molecular and Cellular Biology. 25: 7803-11. PMID 16107725 DOI: 10.1128/Mcb.25.17.7803-7811.2005 |
0.779 |
|
| 2005 |
Wood A, Schneider J, Shilatifard A. Cross-talking histones: implications for the regulation of gene expression and DNA repair. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 83: 460-7. PMID 16094449 DOI: 10.1139/O05-116 |
0.478 |
|
| 2005 |
Kong SE, Banks CA, Shilatifard A, Conaway JW, Conaway RC. ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL. Proceedings of the National Academy of Sciences of the United States of America. 102: 10094-8. PMID 16006523 DOI: 10.1073/Pnas.0503017102 |
0.677 |
|
| 2005 |
Wiederschain D, Kawai H, Shilatifard A, Yuan ZM. Multiple mixed lineage leukemia (MLL) fusion proteins suppress p53-mediated response to DNA damage. The Journal of Biological Chemistry. 280: 24315-21. PMID 15851483 DOI: 10.1074/Jbc.M412237200 |
0.342 |
|
| 2005 |
Tenney K, Shilatifard A. A COMPASS in the voyage of defining the role of trithorax/MLL-containing complexes: linking leukemogensis to covalent modifications of chromatin. Journal of Cellular Biochemistry. 95: 429-36. PMID 15786493 DOI: 10.1002/Jcb.20421 |
0.46 |
|
| 2005 |
Emre NC, Ingvarsdottir K, Wyce A, Wood A, Krogan NJ, Henry KW, Li K, Marmorstein R, Greenblatt JF, Shilatifard A, Berger SL. Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. Molecular Cell. 17: 585-94. PMID 15721261 DOI: 10.1016/J.Molcel.2005.01.007 |
0.427 |
|
| 2005 |
Gerber M, Tenney K, Conaway JW, Conaway RC, Eissenberg JC, Shilatifard A. Regulation of heat shock gene expression by RNA polymerase II elongation factor, Elongin A. The Journal of Biological Chemistry. 280: 4017-20. PMID 15611125 DOI: 10.1074/Jbc.C400487200 |
0.8 |
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| 2004 |
Gerber M, Eissenberg JC, Kong S, Tenney K, Conaway JW, Conaway RC, Shilatifard A. In vivo requirement of the RNA polymerase II elongation factor elongin A for proper gene expression and development. Molecular and Cellular Biology. 24: 9911-9. PMID 15509793 DOI: 10.1128/Mcb.24.22.9911-9919.2004 |
0.826 |
|
| 2004 |
Shilatifard A. Transcriptional elongation control by RNA polymerase II: a new frontier. Biochimica Et Biophysica Acta. 1677: 79-86. PMID 15020049 DOI: 10.1016/J.Bbaexp.2003.11.013 |
0.516 |
|
| 2004 |
Schneider J, Dover J, Johnston M, Shilatifard A. Global proteomic analysis of S. cerevisiae (GPS) to identify proteins required for histone modifications. Methods in Enzymology. 377: 227-34. PMID 14979028 DOI: 10.1016/S0076-6879(03)77013-X |
0.352 |
|
| 2004 |
Wood A, Shilatifard A. Posttranslational modifications of histones by methylation. Advances in Protein Chemistry. 67: 201-22. PMID 14969729 DOI: 10.1016/S0065-3233(04)67008-2 |
0.483 |
|
| 2003 |
Kong SE, Shilatifard A, Conaway RC, Conaway JW. Preparation and Assay of RNA Polymerase II Elongation Factors Elongin and ELL Methods in Enzymology. 371: 276-283. PMID 14712707 DOI: 10.1016/S0076-6879(03)71020-9 |
0.65 |
|
| 2003 |
Henry KW, Wyce A, Lo WS, Duggan LJ, Emre NC, Kao CF, Pillus L, Shilatifard A, Osley MA, Berger SL. Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes & Development. 17: 2648-63. PMID 14563679 DOI: 10.1101/Gad.1144003 |
0.507 |
|
| 2003 |
Wood A, Schneider J, Dover J, Johnston M, Shilatifard A. The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p. The Journal of Biological Chemistry. 278: 34739-42. PMID 12876294 DOI: 10.1074/Jbc.C300269200 |
0.509 |
|
| 2003 |
Wiederschain D, Kawai H, Gu J, Shilatifard A, Yuan ZM. Molecular basis of p53 functional inactivation by the leukemic protein MLL-ELL. Molecular and Cellular Biology. 23: 4230-46. PMID 12773566 DOI: 10.1128/Mcb.23.12.4230-4246.2003 |
0.309 |
|
| 2003 |
Krogan NJ, Kim M, Tong A, Golshani A, Cagney G, Canadien V, Richards DP, Beattie BK, Emili A, Boone C, Shilatifard A, Buratowski S, Greenblatt J. Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Molecular and Cellular Biology. 23: 4207-18. PMID 12773564 DOI: 10.1128/Mcb.23.12.4207-4218.2003 |
0.459 |
|
| 2003 |
Gerber M, Shilatifard A. Transcriptional elongation by RNA polymerase II and histone methylation. The Journal of Biological Chemistry. 278: 26303-6. PMID 12764140 DOI: 10.1074/Jbc.R300014200 |
0.8 |
|
| 2003 |
Shilatifard A, Conaway RC, Conaway JW. The RNA polymerase II elongation complex. Annual Review of Biochemistry. 72: 693-715. PMID 12676794 DOI: 10.1146/Annurev.Biochem.72.121801.161551 |
0.663 |
|
| 2003 |
Krogan NJ, Dover J, Wood A, Schneider J, Heidt J, Boateng MA, Dean K, Ryan OW, Golshani A, Johnston M, Greenblatt JF, Shilatifard A. The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Molecular Cell. 11: 721-9. PMID 12667454 DOI: 10.1016/S1097-2765(03)00091-1 |
0.503 |
|
| 2003 |
Wood A, Krogan NJ, Dover J, Schneider J, Heidt J, Boateng MA, Dean K, Golshani A, Zhang Y, Greenblatt JF, Johnston M, Shilatifard A. Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Molecular Cell. 11: 267-74. PMID 12535539 DOI: 10.1016/S1097-2765(02)00802-X |
0.457 |
|
| 2002 |
Krogan NJ, Kim M, Ahn SH, Zhong G, Kobor MS, Cagney G, Emili A, Shilatifard A, Buratowski S, Greenblatt JF. RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach. Molecular and Cellular Biology. 22: 6979-92. PMID 12242279 DOI: 10.1128/Mcb.22.20.6979-6992.2002 |
0.494 |
|
| 2002 |
Eissenberg JC, Ma J, Gerber MA, Christensen A, Kennison JA, Shilatifard A. dELL is an essential RNA polymerase II elongation factor with a general role in development. Proceedings of the National Academy of Sciences of the United States of America. 99: 9894-9. PMID 12096188 DOI: 10.1073/Pnas.152193699 |
0.795 |
|
| 2002 |
Dover J, Schneider J, Tawiah-Boateng MA, Wood A, Dean K, Johnston M, Shilatifard A. Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6. The Journal of Biological Chemistry. 277: 28368-71. PMID 12070136 DOI: 10.1074/Jbc.C200348200 |
0.417 |
|
| 2002 |
Krogan NJ, Dover J, Khorrami S, Greenblatt JF, Schneider J, Johnston M, Shilatifard A. COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression. The Journal of Biological Chemistry. 277: 10753-5. PMID 11805083 DOI: 10.1074/Jbc.C200023200 |
0.472 |
|
| 2001 |
Gerber M, Ma J, Dean K, Eissenberg JC, Shilatifard A. Drosophila ELL is associated with actively elongating RNA polymerase II on transcriptionally active sites in vivo. The Embo Journal. 20: 6104-14. PMID 11689450 DOI: 10.1093/Emboj/20.21.6104 |
0.783 |
|
| 2001 |
Miller T, Krogan NJ, Dover J, Erdjument-Bromage H, Tempst P, Johnston M, Greenblatt JF, Shilatifard A. COMPASS: a complex of proteins associated with a trithorax-related SET domain protein. Proceedings of the National Academy of Sciences of the United States of America. 98: 12902-7. PMID 11687631 DOI: 10.1073/Pnas.231473398 |
0.427 |
|
| 2001 |
Kamura T, Burian D, Yan Q, Schmidt SL, Lane WS, Querido E, Branton PE, Shilatifard A, Conaway RC, Conaway JW. Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase. The Journal of Biological Chemistry. 276: 29748-53. PMID 11384984 DOI: 10.1074/Jbc.M103093200 |
0.783 |
|
| 2001 |
Kamura T, Burian D, Khalili H, Schmidt SL, Sato S, Liu WJ, Conrad MN, Conaway RC, Conaway JW, Shilatifard A. Cloning and characterization of ELL-associated proteins EAP45 and EAP20. a role for yeast EAP-like proteins in regulation of gene expression by glucose. The Journal of Biological Chemistry. 276: 16528-33. PMID 11278625 DOI: 10.1074/Jbc.M010142200 |
0.794 |
|
| 2001 |
Elmendorf BJ, Shilatifard A, Yan Q, Conaway JW, Conaway RC. Transcription Factors TFIIF, ELL, and Elongin Negatively Regulate SII-induced Nascent Transcript Cleavage by Non-arrested RNA Polymerase II Elongation Intermediates Journal of Biological Chemistry. 276: 23109-23114. PMID 11259417 DOI: 10.1074/Jbc.M101445200 |
0.667 |
|
| 2001 |
Johnstone RW, Gerber M, Landewe T, Tollefson A, Wold WS, Shilatifard A. Functional analysis of the leukemia protein ELL: Evidence for a role in the regulation of cell growth and survival Molecular and Cellular Biology. 21: 1672-1681. PMID 11238904 DOI: 10.1128/Mcb.21.5.1672-1681.2001 |
0.758 |
|
| 2000 |
Conaway JW, Shilatifard A, Dvir A, Conaway RC. Control of elongation by RNA polymerase II Trends in Biochemical Sciences. 25: 375-380. PMID 10916156 DOI: 10.1016/S0968-0004(00)01615-7 |
0.669 |
|
| 2000 |
Miller T, Williams K, Johnstone RW, Shilatifard A. Identification, cloning, expression, and biochemical characterization of the testis-specific RNA polymerase II elongation factor ELL3. The Journal of Biological Chemistry. 275: 32052-6. PMID 10882741 DOI: 10.1074/Jbc.M005175200 |
0.504 |
|
| 2000 |
Schang LM, Hwang GJ, Dynlacht BD, Speicher DW, Bantly A, Schaffer PA, Shilatifard A, Ge H, Shiekhattar R. Human PC4 is a substrate-specific inhibitor of RNA polymerase II phosphorylation. The Journal of Biological Chemistry. 275: 6071-4. PMID 10692395 DOI: 10.1074/Jbc.275.9.6071 |
0.346 |
|
| 2000 |
Caslini C, Shilatifard A, Yang L, Hess JL. The amino terminus of the mixed lineage leukemia protein (MLL) promotes cell cycle arrest and monocytic differentiation. Proceedings of the National Academy of Sciences of the United States of America. 97: 2797-802. PMID 10688900 DOI: 10.1073/Pnas.040574897 |
0.341 |
|
| 2000 |
DiMartino JF, Miller T, Ayton PM, Landewe T, Hess JL, Cleary ML, Shilatifard A. A carboxy-terminal domain of ELL is required and sufficient for immortalization of myeloid progenitors by MLL-ELL Blood. 96: 3887-3893. DOI: 10.1182/Blood.V96.12.3887.H8003887_3887_3893 |
0.469 |
|
| 1999 |
Schmidt AE, Miller T, Schmidt SL, Shiekhattar R, Shilatifard A. Cloning and characterization of the EAP30 subunit of the ELL complex that confers derepression of transcription by RNA polymerase II. The Journal of Biological Chemistry. 274: 21981-5. PMID 10419521 DOI: 10.1074/Jbc.274.31.21981 |
0.536 |
|
| 1999 |
Brower CS, Shilatifard A, Mather T, Kamura T, Takagi Y, Haque D, Treharne A, Foundling SI, Conaway JW, Conaway RC. The Elongin B ubiquitin homology domain. Identification of Elongin B sequences important for interaction with Elongin C Journal of Biological Chemistry. 274: 13629-13636. PMID 10224134 DOI: 10.1074/Jbc.274.19.13629 |
0.764 |
|
| 1999 |
Bochar DA, Pan ZQ, Knights R, Fisher RP, Shilatifard A, Shiekhattar R. Inhibition of transcription by the trimeric cyclin-dependent kinase 7 complex. The Journal of Biological Chemistry. 274: 13162-6. PMID 10224071 DOI: 10.1074/Jbc.274.19.13162 |
0.491 |
|
| 1998 |
Shilatifard A. Factors regulating the transcriptional elongation activity of RNA polymerase II. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 1437-46. PMID 9806752 DOI: 10.1096/Fasebj.12.14.1437 |
0.512 |
|
| 1998 |
Shilatifard A. Identification and purification of the Holo-ELL complex. Evidence for the presence of ELL-associated proteins that suppress the transcriptional inhibitory activity of ELL. The Journal of Biological Chemistry. 273: 11212-7. PMID 9556611 DOI: 10.1074/Jbc.273.18.11212 |
0.547 |
|
| 1998 |
Shilatifard A. The RNA polymerase II general elongation complex. Biological Chemistry. 379: 27-31. PMID 9504713 DOI: 10.1515/Bchm.1998.379.1.27 |
0.514 |
|
| 1997 |
Shilatifard A, Haque D, Conaway RC, Conaway JW. Structure and function of RNA polymerase II elongation factor ELL: Identification of two overlapping ell functional domains that govern its interaction with polymerase and the ternary elongation complex Journal of Biological Chemistry. 272: 22355-22363. PMID 9268387 DOI: 10.1074/Jbc.272.35.22355 |
0.681 |
|
| 1997 |
Shilatifard A, Conaway JW, Conaway RC. Mechanism and regulation of transcriptional elongation and termination by RNA polymerase II Current Opinion in Genetics and Development. 7: 199-204. PMID 9115429 DOI: 10.1016/S0959-437X(97)80129-3 |
0.664 |
|
| 1997 |
Shilatifard A, Duan DR, Haque D, Florence C, Schubach WH, Conaway JW, Conaway RC. ELL2, a new member of an ELL family of RNA polymerase II elongation factors Proceedings of the National Academy of Sciences of the United States of America. 94: 3639-3643. PMID 9108030 DOI: 10.1073/pnas.94.8.3639 |
0.644 |
|
| 1997 |
Prieto PA, Larsen RD, Cho M, Rivera HN, Shilatifard A, Lowe JB, Cummings RD, Smith DF. Expression of human H-type alpha1,2-fucosyltransferase encoding for blood group H(O) antigen in Chinese hamster ovary cells. Evidence for preferential fucosylation and truncation of polylactosamine sequences. The Journal of Biological Chemistry. 272: 2089-97. PMID 8999907 DOI: 10.1074/Jbc.272.4.2089 |
0.468 |
|
| 1996 |
Aso T, Shilatifard A, Conaway JW, Conaway RC. Transcription syndromes and the role of RNA polymerase II general transcription factors in human disease Journal of Clinical Investigation. 97: 1561-1569. PMID 8601619 DOI: 10.1172/Jci118580 |
0.822 |
|
| 1996 |
Shilatifard A, Lane WS, Jackson KW, Conaway RC, Conaway JW. An RNA polymerase II elongation factor encoded by the human ELL gene Science. 271: 1873-1876. PMID 8596958 DOI: 10.1126/Science.271.5257.1873 |
0.682 |
|
| 1995 |
Shilatifard A, Cummings RD. Sulphate release from keratan sulphate and heparan sulphate by bovine N-acetylglucosamine-6-sulphate sulphatase. Glycobiology. 5: 291-7. PMID 7655166 DOI: 10.1093/Glycob/5.3.291 |
0.458 |
|
| 1993 |
Shilatifard A, Merkle RK, Helland DE, Welles JL, Haseltine WA, Cummings RD. Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine. Journal of Virology. 67: 943-52. PMID 8419650 DOI: 10.1128/Jvi.67.2.943-952.1993 |
0.445 |
|
| 1991 |
Merkle RK, Helland DE, Welles JL, Shilatifard A, Haseltine WA, Cummings RD. gp160 of HIV-I synthesized by persistently infected Molt-3 cells is terminally glycosylated: evidence that cleavage of gp160 occurs subsequent to oligosaccharide processing. Archives of Biochemistry and Biophysics. 290: 248-57. PMID 1898096 DOI: 10.1016/0003-9861(91)90616-Q |
0.436 |
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