Michele A. Kutzler - Publications

Affiliations: 
Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
Cell Biology, Microbiology Biology, Molecular Biology

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Connors J, Cusimano G, Mege N, Woloszczuk K, Konopka E, Bell M, Joyner D, Marcy J, Tardif V, Kutzler MA, Muir R, Haddad EK. Using the power of innate immunoprofiling to understand vaccine design, infection, and immunity. Human Vaccines & Immunotherapeutics. 19: 2267295. PMID 37885158 DOI: 10.1080/21645515.2023.2267295  0.519
2023 Gary EN, Tursi NJ, Warner BM, Cuismano G, Connors J, Parzych EM, Griffin BD, Bell MR, Ali AR, Frase D, Hojecki CE, Canziani GA, Chaiken I, Kannan T, Moffat E, ... ... Kutzler MA, et al. Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge. Frontiers in Immunology. 14: 1138609. PMID 36999023 DOI: 10.3389/fimmu.2023.1138609  0.54
2023 Connors J, Joyner D, Mege NJ, Cusimano GM, Bell MR, Marcy J, Taramangalam B, Kim KM, Lin PJC, Tam YK, Weissman D, Kutzler MA, Alameh MG, Haddad EK. Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals. Communications Biology. 6: 188. PMID 36805684 DOI: 10.1038/s42003-023-04555-1  0.387
2022 Connors J, Joyner D, Mege N, Cusimano G, Bell M, Marcy J, Taramangalam B, Lin P, Tam Y, Lin P, Weissman D, Kutzler M, Alameh MG, Haddad E. Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals. Research Square. PMID 36380763 DOI: 10.21203/rs.3.rs-2199652/v1  0.384
2022 Cusimano GM, Gary EN, Bell MR, Warner BM, Connors J, Tursi NJ, Ali AR, Zhang S, Canziani G, Taramangalam B, Gordon EA, Chaiken IM, Wootton SK, Smith T, Ramos S, ... ... Kutzler MA, et al. Improved Durability to SARS-CoV-2 Vaccine Immunity following Coimmunization with Molecular Adjuvant Adenosine Deaminase-1. Journal of Immunology (Baltimore, Md. : 1950). 209: 118-127. PMID 35750334 DOI: 10.4049/jimmunol.2200056  0.501
2022 Bell MR, Kutzler MA. An old problem with new solutions: Strategies to improve vaccine efficacy in the elderly. Advanced Drug Delivery Reviews. 183: 114175. PMID 35202770 DOI: 10.1016/j.addr.2022.114175  0.553
2022 Izmirly AM, Pelletier AN, Connors J, Taramangalam B, Alturki SO, Gordon EA, Alturki SO, Mell JC, Swaminathan G, Karthik V, Kutzler MA, Kallas EG, Sekaly RP, Haddad EK. Pre-vaccination frequency of circulatory Tfh is associated with robust immune response to TV003 dengue vaccine. Plos Pathogens. 18: e1009903. PMID 35061851 DOI: 10.1371/journal.ppat.1009903  0.596
2021 Connors J, Bell MR, Marcy J, Kutzler M, Haddad EK. The impact of immuno-aging on SARS-CoV-2 vaccine development. Geroscience. PMID 33569701 DOI: 10.1007/s11357-021-00323-3  0.467
2020 Alturki SO, Alturki SO, Connors J, Cusimano G, Kutzler MA, Izmirly AM, Haddad EK. The 2020 Pandemic: Current SARS-CoV-2 Vaccine Development. Frontiers in Immunology. 11: 1880. PMID 32973779 DOI: 10.3389/Fimmu.2020.01880  0.427
2020 Mohamed H, Esposito RA, Kutzler MA, Wigdahl B, Krebs FC, Miller V. Nonthermal plasma as part of a novel strategy for vaccination. Plasma Processes and Polymers (Print). e2000051. PMID 32837491 DOI: 10.1002/Ppap.202000051  0.586
2020 Gary E, O'Connor M, Chakhtoura M, Tardif V, Kumova OK, Malherbe DC, Sutton WF, Haigwood NL, Kutzler MA, Haddad EK. Adenosine deaminase-1 enhances germinal center formation and functional antibody responses to HIV-1 Envelope DNA and protein vaccines. Vaccine. PMID 32280045 DOI: 10.1016/J.Vaccine.2020.03.047  0.675
2020 Gary EN, Kathuria N, Makurumidze G, Curatola A, Ramamurthi A, Bernui ME, Myles D, Yan J, Pankhong P, Muthumani K, Haddad E, Humeau L, Weiner DB, Kutzler MA. CCR10 expression is required for the adjuvant activity of the mucosal chemokine CCL28 when delivered in the context of an HIV-1 Env DNA vaccine. Vaccine. PMID 32057572 DOI: 10.1016/J.Vaccine.2020.01.023  0.747
2020 Ang CG, Hossain MA, Rajpara M, Bach H, Acharya K, Dick A, Rashad AA, Kutzler M, Abrams CF, Chaiken I. Metastable HIV-1 Surface Protein Env Sensitizes Cell Membranes to Transformation and Poration by Dual-Acting Virucidal Entry Inhibitors. Biochemistry. PMID 31942789 DOI: 10.1021/Acs.Biochem.9B01008  0.355
2018 Gary EN, Kutzler MA. Defensive Driving: Directing HIV-1 Vaccine-Induced Humoral Immunity to the Mucosa with Chemokine Adjuvants. Journal of Immunology Research. 2018: 3734207. PMID 30648120 DOI: 10.1155/2018/3734207  0.685
2018 Rashad AA, Song LR, Holmes AP, Acharya K, Zhang S, Wang ZL, Gary E, Xie X, Pirrone V, Kutzler MA, Long YQ, Chaiken I. Bifunctional Chimera That Coordinately Targets Human Immunodeficiency Virus 1 (HIV-1) Envelope gp120 and Host Cell CCR5 Co-receptor at the Virus-Cell Interface. Journal of Medicinal Chemistry. PMID 29767965 DOI: 10.1021/Acs.Jmedchem.8B00477  0.371
2017 Vinnard C, Manley I, Scott B, Bernui M, Adams J, Varghese S, Zentner I, Kutzler MA. A Pilot Study of Immune Activation and Rifampin Absorption in HIV-Infected Patients without Tuberculosis Infection: A Short Report. Tuberculosis Research and Treatment. 2017: 2140974. PMID 29430306 DOI: 10.1155/2017/2140974  0.405
2017 Gary EN, Kutzler MA. A Little Help From the Follicles: Understanding the Germinal Center Response to Human Immunodeficiency Virus 1 Infection and Prophylactic Vaccines. Clinical Medicine Insights. Pathology. 10: 1179555717695548. PMID 28469517 DOI: 10.1177/1179555717695548  0.561
2017 Latimer BP, Gary E, Kutzler MA. Developments Towards a Prophylactic Hepatitis C Virus Vaccine Current Immunology Reviews. 12: 83-97. DOI: 10.2174/1877944106999160429155400  0.764
2015 Kutzler MA, Wise MC, Hutnick NA, Moldoveanu Z, Hunter M, Reuter MA, Yuan S, Yan J, Ginsberg AA, Sylvester A, Pahar B, Carnathan DG, Kathuria N, Khan AS, Montefiori D, et al. Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge. Mucosal Immunology. PMID 25943275 DOI: 10.1038/Mi.2015.31  0.773
2014 Latimer B, Toporovski R, Yan J, Pankhong P, Morrow MP, Khan AS, Sardesai NY, Welles SL, Jacobson JM, Weiner DB, Kutzler MA. Strong HCV NS3/4a, NS4b, NS5a, NS5b-specific cellular immune responses induced in Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine. Human Vaccines & Immunotherapeutics. 10: 2357-65. PMID 25424943 DOI: 10.4161/Hv.29590  0.777
2014 Baliban SM, Michael A, Shammassian B, Mudakha S, Khan AS, Cocklin S, Zentner I, Latimer BP, Bouillaut L, Hunter M, Marx P, Sardesai NY, Welles SL, Jacobson JM, Weiner DB, ... Kutzler MA, et al. An optimized, synthetic DNA vaccine encoding the toxin A and toxin B receptor binding domains of Clostridium difficile induces protective antibody responses in vivo. Infection and Immunity. 82: 4080-91. PMID 25024365 DOI: 10.1128/Iai.01950-14  0.76
2012 Kathuria N, Kraynyak KA, Carnathan D, Betts M, Weiner DB, Kutzler MA. Generation of antigen-specific immunity following systemic immunization with DNA vaccine encoding CCL25 chemokine immunoadjuvant. Human Vaccines & Immunotherapeutics. 8: 1607-19. PMID 23151454 DOI: 10.4161/Hv.22574  0.77
2012 Reuter MA, Yuan S, Marx PA, Kutzler MA, Weiner DB, Betts MR. DNA-based HIV vaccines do not induce generalized activation in mucosal tissue T cells. Human Vaccines & Immunotherapeutics. 8: 1648-53. PMID 23111167 DOI: 10.4161/Hv.22247  0.591
2012 Connolly RJ, Chapman T, Hoff AM, Kutzler MA, Jaroszeski MJ, Ugen KE. Non-contact helium-based plasma for delivery of DNA vaccines. Enhancement of humoral and cellular immune responses. Human Vaccines & Immunotherapeutics. 8: 1729-33. PMID 22894954 DOI: 10.4161/Hv.21624  0.644
2012 Hutnick N, Myles D, Ginsberg A, Khan A, Yan J, Moldoveanu Z, Mestecky J, Marx P, Kutzler M, Weiner D. Improved systemic and mucosal antibody responses with a CCR10 ligand adjuvant Retrovirology. 9: 203. DOI: 10.1186/1742-4690-9-S2-P203  0.673
2011 Belisle SE, Yin J, Shedlock DJ, Dai A, Yan J, Hirao L, Kutzler MA, Lewis MG, Andersen H, Lank SM, Karl JA, O'Connor DH, Khan A, Sardesai N, Chang J, et al. Long-term programming of antigen-specific immunity from gene expression signatures in the PBMC of rhesus macaques immunized with an SIV DNA vaccine. Plos One. 6: e19681. PMID 21701683 DOI: 10.1371/Journal.Pone.0019681  0.669
2011 Chertov O, Zhang N, Chen X, Oppenheim JJ, Lubkowski J, McGrath C, Sowder RC, Crise BJ, Malyguine A, Kutzler MA, Steele AD, Henderson EE, Rogers TJ. Novel peptides based on HIV-1 gp120 sequence with homology to chemokines inhibit HIV infection in cell culture. Plos One. 6: e14474. PMID 21264298 DOI: 10.1371/Journal.Pone.0014474  0.361
2011 Yin J, Dai A, Lecureux J, Arango T, Kutzler MA, Yan J, Lewis MG, Khan A, Sardesai NY, Montefiore D, Ruprecht R, Weiner DB, Boyer JD. High antibody and cellular responses induced to HIV-1 clade C envelope following DNA vaccines delivered by electroporation. Vaccine. 29: 6763-70. PMID 21195801 DOI: 10.1016/J.Vaccine.2010.12.055  0.727
2011 Happel C, Kutzler M, Rogers TJ. Opioid-induced chemokine expression requires NF-κB activity: the role of PKCζ. Journal of Leukocyte Biology. 89: 301-9. PMID 20952659 DOI: 10.1189/Jlb.0710402  0.302
2010 Kraynyak KA, Kutzler MA, Cisper NJ, Khan AS, Draghia-Akli R, Sardesal NY, Lewis MG, Yan J, Weiner DB. Systemic immunization with CCL27/CTACK modulates immune responses at mucosal sites in mice and macaques. Vaccine. 28: 1942-51. PMID 20188250 DOI: 10.1016/J.Vaccine.2009.10.095  0.673
2010 Daley LP, Kutzler MA, Bennett BW, Smith MC, Glaser AL, Appleton JA. Effector functions of camelid heavy-chain antibodies in immunity to West Nile virus. Clinical and Vaccine Immunology : Cvi. 17: 239-46. PMID 19955323 DOI: 10.1128/CVI.00421-09  0.439
2010 Kutzler MA, Kraynyak KA, Nagle SJ, Parkinson RM, Zharikova D, Chattergoon M, Maguire H, Muthumani K, Ugen K, Weiner DB. Plasmids encoding the mucosal chemokines CCL27 and CCL28 are effective adjuvants in eliciting antigen-specific immunity in vivo. Gene Therapy. 17: 72-82. PMID 19847203 DOI: 10.1038/Gt.2009.112  0.698
2009 Yin J, Dai A, Laddy DJ, Yan J, Arango T, Khan AS, Lewis MG, Andersen H, Kutzler MA, Draghia-Akli R, Weiner DB, Boyer JD. High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model. Virology. 393: 49-55. PMID 19683780 DOI: 10.1016/J.Virol.2009.07.017  0.427
2009 Kraynyak KA, Kutzler MA, Cisper NJ, Laddy DJ, Morrow MP, Waldmann TA, Weiner DB. Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo. Human Gene Therapy. 20: 1143-56. PMID 19530914 DOI: 10.1089/Hum.2009.025  0.528
2009 Ramanathan MP, Kutzler MA, Kuo YC, Yan J, Liu H, Shah V, Bawa A, Selling B, Sardesai NY, Kim JJ, Weiner DB. Coimmunization with an optimized IL15 plasmid adjuvant enhances humoral immunity via stimulating B cells induced by genetically engineered DNA vaccines expressing consensus JEV and WNV E DIII. Vaccine. 27: 4370-80. PMID 19497647 DOI: 10.1016/J.Vaccine.2009.01.137  0.649
2009 Kraynyak KA, Kutzler MA, Pahar B, Sylvester A, Yan J, Carnathan D, Khan AS, Sardesai N, Moldoveanu Z, Mestecky J, Betts MR, Marx P, Weiner DB. P19-46. Co-delivery of mucosal chemokine plasmids in a systemically delivered DNA vaccine elicits systemic and mucosal immune responses in mice and macaques Retrovirology. 6: P366. DOI: 10.1186/1742-4690-6-S3-P366  0.668
2008 Kutzler MA, Jacobson JM. Treatment interruption as a tool to measure changes in immunologic response to HIV-1. Current Opinion in Hiv and Aids. 3: 131-5. PMID 19372954 DOI: 10.1097/Coh.0B013E3282F54Cde  0.466
2008 Kutzler MA, Weiner DB. DNA vaccines: ready for prime time? Nature Reviews. Genetics. 9: 776-88. PMID 18781156 DOI: 10.1038/Nrg2432  0.599
2008 Yin J, Dai A, Kutzler MA, Shen A, Lecureux J, Lewis MG, Waldmann T, Weiner DB, Boyer JD. Sustained suppression of SHIV89.6P replication in macaques by vaccine-induced CD8+ memory T cells. Aids (London, England). 22: 1739-48. PMID 18753858 DOI: 10.1097/Qad.0B013E32830Efdae  0.53
2008 Laddy DJ, Yan J, Kutzler M, Kobasa D, Kobinger GP, Khan AS, Greenhouse J, Sardesai NY, Draghia-Akli R, Weiner DB. Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens. Plos One. 3: e2517. PMID 18575608 DOI: 10.1371/Journal.Pone.0002517  0.615
2007 Boyer JD, Robinson TM, Kutzler MA, Vansant G, Hokey DA, Kumar S, Parkinson R, Wu L, Sidhu MK, Pavlakis GN, Felber BK, Brown C, Silvera P, Lewis MG, Monforte J, et al. Protection against simian/human immunodeficiency virus (SHIV) 89.6P in macaques after coimmunization with SHIV antigen and IL-15 plasmid. Proceedings of the National Academy of Sciences of the United States of America. 104: 18648-53. PMID 18000037 DOI: 10.1073/Pnas.0709198104  0.666
2007 McMurry JA, Kimball S, Lee JH, Rivera D, Martin W, Weiner DB, Kutzler M, Sherman DR, Kornfeld H, De Groot AS. Epitope-driven TB vaccine development: a streamlined approach using immuno-informatics, ELISpot assays, and HLA transgenic mice. Current Molecular Medicine. 7: 351-68. PMID 17584075 DOI: 10.2174/156652407780831584  0.604
2007 Chong SY, Egan MA, Kutzler MA, Megati S, Masood A, Roopchard V, Garcia-Hand D, Montefiori DC, Quiroz J, Rosati M, Schadeck EB, Boyer JD, Pavlakis GN, Weiner DB, Sidhu M, et al. Comparative ability of plasmid IL-12 and IL-15 to enhance cellular and humoral immune responses elicited by a SIVgag plasmid DNA vaccine and alter disease progression following SHIV(89.6P) challenge in rhesus macaques. Vaccine. 25: 4967-82. PMID 17335943 DOI: 10.1016/J.Vaccine.2006.11.070  0.521
2007 Yan J, Yoon H, Kumar S, Ramanathan MP, Corbitt N, Kutzler M, Dai A, Boyer JD, Weiner DB. Enhanced cellular immune responses elicited by an engineered HIV-1 subtype B consensus-based envelope DNA vaccine. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 411-21. PMID 17235321 DOI: 10.1038/Sj.Mt.6300036  0.678
2006 Kutzler MA, Cao C, Bai Y, Dong H, Choe PY, Saulino V, McLaughlin L, Whelan A, Choo AY, Weiner DB, Ugen KE. Mapping of immune responses following wild-type and mutant ABeta42 plasmid or peptide vaccination in different mouse haplotypes and HLA Class II transgenic mice. Vaccine. 24: 4630-9. PMID 16157426 DOI: 10.1016/J.Vaccine.2005.08.036  0.535
2006 Kutzler MA, Schoenly KA, Muthumani K, Parkinson RM, Maquire H, Ugen K, Weiner D. Novel strategy for generation of mucosal immune responses against HIV-1 following systemic vaccination Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-S30  0.691
2005 Boyer JD, Robinson TM, Kutzler MA, Parkinson R, Calarota SA, Sidhu MK, Muthumani K, Lewis M, Pavlakis G, Felber B, Weiner D. SIV DNA vaccine co-administered with IL-12 expression plasmid enhances CD8 SIV cellular immune responses in cynomolgus macaques. Journal of Medical Primatology. 34: 262-70. PMID 16128921 DOI: 10.1111/J.1600-0684.2005.00124.X  0.658
2005 Kutzler MA, Robinson TM, Chattergoon MA, Choo DK, Choo AY, Choe PY, Ramanathan MP, Parkinson R, Kudchodkar S, Tamura Y, Sidhu M, Roopchand V, Kim JJ, Pavlakis GN, Felber BK, et al. Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help. Journal of Immunology (Baltimore, Md. : 1950). 175: 112-23. PMID 15972637 DOI: 10.4049/Jimmunol.175.1.112  0.514
2005 De Groot AS, Marcon L, Bishop EA, Rivera D, Kutzler M, Weiner DB, Martin W. HIV vaccine development by computer assisted design: the GAIA vaccine. Vaccine. 23: 2136-48. PMID 15755584 DOI: 10.1016/J.Vaccine.2005.01.097  0.567
2005 Groot ASD, McMurry J, Marcon L, Franco J, Rivera D, Kutzler M, Weiner D, Martin B. Developing an epitope-driven tuberculosis (TB) vaccine Vaccine. 23: 2121-2131. PMID 15755582 DOI: 10.1016/J.Vaccine.2005.01.059  0.578
2004 Kutzler MA, Weiner DB. Developing DNA vaccines that call to dendritic cells. The Journal of Clinical Investigation. 114: 1241-4. PMID 15520855 DOI: 10.1172/Jci23467  0.675
2003 Boyer JD, Kutzler MA, Chattergoon MA, Calarota SA, Pavlakis G, Sekaly RP, MacGregor RR, Weiner DB. Engineering DNA vaccination as an approach to HIV immune therapy Clinical and Applied Immunology Reviews. 3: 183-197. DOI: 10.1016/S1529-1049(02)00158-7  0.695
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