| Year |
Citation |
Score |
| 2021 |
Xiong M, Jiang H, Serrano JR, Gonzales ER, Wang C, Gratuze M, Hoyle R, Bien-Ly N, Silverman AP, Sullivan PM, Watts RJ, Ulrich JD, Zipfel GJ, Holtzman DM. APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function. Science Translational Medicine. 13. PMID 33597265 DOI: 10.1126/scitranslmed.abd7522 |
0.59 |
|
| 2018 |
Liao F, Li A, Xiong M, Bien-Ly N, Jiang H, Zhang Y, Finn MB, Hoyle R, Keyser J, Lefton KB, Robinson GO, Serrano JR, Silverman AP, Guo JL, Getz J, et al. Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation. The Journal of Clinical Investigation. PMID 29600961 DOI: 10.1172/Jci96429 |
0.609 |
|
| 2016 |
Rajapaksa KS, Huang T, Sharma N, Liu S, Solon M, Reyes A, Paul S, Yee A, Tao J, Chalasani S, Bien-Ly N, Barck K, Carano RA, Wang J, Rangell L, et al. Preclinical safety profile of a depleting antibody against CRTh2 for asthma: Well tolerated despite unexpected CRTh2 expression on vascular pericytes in the central nervous system and gastric mucosa. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27103662 DOI: 10.1093/Toxsci/Kfw067 |
0.367 |
|
| 2015 |
Zuchero YJ, Chen X, Bien-Ly N, Bumbaca D, Tong RK, Gao X, Zhang S, Hoyte K, Luk W, Huntley MA, Phu L, Tan C, Kallop D, Weimer RM, Lu Y, et al. Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies. Neuron. PMID 26687840 DOI: 10.1016/J.Neuron.2015.11.024 |
0.628 |
|
| 2015 |
Bien-Ly N, Boswell CA, Jeet S, Beach TG, Hoyte K, Luk W, Shihadeh V, Ulufatu S, Foreman O, Lu Y, DeVoss J, van der Brug M, Watts RJ. Lack of Widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies. Neuron. 88: 289-97. PMID 26494278 DOI: 10.1016/J.Neuron.2015.09.036 |
0.641 |
|
| 2014 |
Huntley MA, Bien-Ly N, Daneman R, Watts RJ. Dissecting gene expression at the blood-brain barrier. Frontiers in Neuroscience. 8: 355. PMID 25414634 DOI: 10.3389/Fnins.2014.00355 |
0.562 |
|
| 2014 |
Bien-Ly N, Watts RJ. The blood-brain barrier's gut check. Science Translational Medicine. 6: 263fs46. PMID 25411469 DOI: 10.1126/Scitranslmed.Aaa2543 |
0.536 |
|
| 2014 |
Yu YJ, Atwal JK, Zhang Y, Tong RK, Wildsmith KR, Tan C, Bien-Ly N, Hersom M, Maloney JA, Meilandt WJ, Bumbaca D, Gadkar K, Hoyte K, Luk W, Lu Y, et al. Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates. Science Translational Medicine. 6: 261ra154. PMID 25378646 DOI: 10.1126/Scitranslmed.3009835 |
0.644 |
|
| 2014 |
Bien-Ly N, Yu YJ, Bumbaca D, Elstrott J, Boswell CA, Zhang Y, Luk W, Lu Y, Dennis MS, Weimer RM, Chung I, Watts RJ. Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants. The Journal of Experimental Medicine. 211: 233-44. PMID 24470444 DOI: 10.1084/Jem.20131660 |
0.615 |
|
| 2012 |
Bien-Ly N, Gillespie AK, Walker D, Yoon SY, Huang Y. Reducing human apolipoprotein E levels attenuates age-dependent Aβ accumulation in mutant human amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4803-11. PMID 22492035 DOI: 10.1523/Jneurosci.0033-12.2012 |
0.364 |
|
| 2011 |
Bien-Ly N, Andrews-Zwilling Y, Xu Q, Bernardo A, Wang C, Huang Y. C-terminal-truncated apolipoprotein (apo) E4 inefficiently clears amyloid-beta (Abeta) and acts in concert with Abeta to elicit neuronal and behavioral deficits in mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 4236-41. PMID 21368138 DOI: 10.1073/Pnas.1018381108 |
0.32 |
|
| 2007 |
Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu GQ, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron. 55: 697-711. PMID 17785178 DOI: 10.1016/J.Neuron.2007.07.025 |
0.347 |
|
| 2007 |
Chin J, Massaro CM, Palop JJ, Thwin MT, Yu GQ, Bien-Ly N, Bender A, Mucke L. Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2727-33. PMID 17360894 DOI: 10.1523/Jneurosci.3758-06.2007 |
0.393 |
|
| 2006 |
Esposito L, Raber J, Kekonius L, Yan F, Yu GQ, Bien-Ly N, Puoliväli J, Scearce-Levie K, Masliah E, Mucke L. Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5167-79. PMID 16687508 DOI: 10.1523/Jneurosci.0482-06.2006 |
0.378 |
|
| 2005 |
Chin J, Palop JJ, Puoliväli J, Massaro C, Bien-Ly N, Gerstein H, Scearce-Levie K, Masliah E, Mucke L. Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9694-703. PMID 16237174 DOI: 10.1523/Jneurosci.2980-05.2005 |
0.302 |
|
| 2005 |
Palop JJ, Chin J, Bien-Ly N, Massaro C, Yeung BZ, Yu GQ, Mucke L. Vulnerability of dentate granule cells to disruption of arc expression in human amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9686-93. PMID 16237173 DOI: 10.1523/Jneurosci.2829-05.2005 |
0.303 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
| 2004 |
Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1 |
0.373 |
|
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