Year |
Citation |
Score |
2024 |
Altman PX, Ozorowski G, Stanfield RL, Haakenson J, Appel M, Parren M, Lee WH, Sang H, Woehl J, Saye-Francisco K, Joyce C, Song G, Porter K, Landais E, Andrabi R, ... Wilson IA, et al. Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Biorxiv : the Preprint Server For Biology. PMID 38405899 DOI: 10.1101/2024.02.13.580058 |
0.309 |
|
2023 |
Martin GM, Torres JL, Pholcharee T, Oyen D, Flores-Garcia Y, Gibson G, Moskovitz R, Beutler N, Jung DD, Copps J, Lee WH, Gonzalez-Paez G, Emerling D, MacGill RS, Locke E, ... ... Wilson IA, et al. Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection. Nature Communications. 14: 4546. PMID 37507365 DOI: 10.1038/s41467-023-40151-x |
0.316 |
|
2023 |
Joyce C, Murrell S, Murrell B, Omorodion O, Ver LS, Carrico N, Bastidas R, Nedellec R, Bick M, Woehl J, Zhao F, Burns A, Barman S, Appel M, Ramos A, ... ... Wilson IA, et al. Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathogens. 19: e1011416. PMID 37384622 DOI: 10.1371/journal.ppat.1011416 |
0.354 |
|
2023 |
Misson Mindrebo L, Liu H, Ozorowski G, Tran Q, Woehl J, Khalek I, Smith JM, Barman S, Zhao F, Keating C, Limbo O, Verma M, Liu J, Stanfield RL, Zhu X, ... ... Wilson IA, et al. Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216612120. PMID 37276407 DOI: 10.1073/pnas.2216612120 |
0.32 |
|
2023 |
Caniels TG, Medina-Ramírez M, Zhang J, Sarkar A, Kumar S, LaBranche A, Derking R, Allen JD, Snitselaar JL, Capella-Pujol J, Sánchez IDM, Yasmeen A, Diaz M, Aldon Y, Bijl TPL, ... ... Wilson IA, et al. Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions. Cell Reports. Medicine. 101003. PMID 37044090 DOI: 10.1016/j.xcrm.2023.101003 |
0.778 |
|
2023 |
Changrob S, Halfmann PJ, Liu H, Torres JL, McGrath JJC, Ozorowski G, Li L, Wilbanks GD, Kuroda M, Maemura T, Huang M, Zheng NY, Turner HL, Erickson SA, Fu Y, ... ... Wilson IA, et al. Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody to antigenically distinct Omicron subvariants. The Journal of Clinical Investigation. PMID 36862518 DOI: 10.1172/JCI166844 |
0.317 |
|
2022 |
van Schooten J, Schorcht A, Farokhi E, Umotoy JC, Gao H, van den Kerkhof TLGM, Dorning J, Rijkhold Meesters TG, van der Woude P, Burger JA, Bijl T, Ghalaiyini R, Torrents de la Peña A, Turner HL, Labranche CC, ... ... Wilson IA, et al. Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer. Plos Pathogens. 18: e1010945. PMID 36395347 DOI: 10.1371/journal.ppat.1010945 |
0.809 |
|
2022 |
Dacon C, Peng L, Lin TH, Tucker C, Lee CD, Cong Y, Wang L, Purser L, Cooper AJR, Williams JK, Pyo CW, Yuan M, Kosik I, Hu Z, Zhao M, ... ... Wilson IA, et al. Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses. Cell Host & Microbe. PMID 36347257 DOI: 10.1016/j.chom.2022.10.010 |
0.301 |
|
2022 |
He L, Chaudhary A, Lin X, Sou C, Alkutkar T, Kumar S, Ngo T, Kosviner E, Ozorowski G, Stanfield RL, Ward AB, Wilson IA, Zhu J. Author Correction: Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines. Nature Communications. 13: 6343. PMID 36284102 DOI: 10.1038/s41467-022-34108-9 |
0.444 |
|
2022 |
Willis JR, Berndsen ZT, Ma KM, Steichen JM, Schiffner T, Landais E, Liguori A, Kalyuzhniy O, Allen JD, Baboo S, Omorodion O, Diedrich JK, Hu X, Georgeson E, Phelps N, ... ... Wilson IA, et al. Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors. Immunity. PMID 36179689 DOI: 10.1016/j.immuni.2022.09.001 |
0.31 |
|
2022 |
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, ... ... Wilson IA, et al. Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques. Science Translational Medicine. 14: eabl9605. PMID 35947674 DOI: 10.1126/scitranslmed.abl9605 |
0.335 |
|
2022 |
van Schooten J, Farokhi E, Schorcht A, van den Kerkhof TLGM, Gao H, van der Woude P, Burger JA, Meesters TGR, Bijl T, Ghalaiyini R, Turner HL, Dorning J, van Schaik BDC, van Kampen AHC, Labranche CC, ... ... Wilson IA, et al. Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein. Nature Communications. 13: 4515. PMID 35922441 DOI: 10.1038/s41467-022-32208-0 |
0.812 |
|
2022 |
Liu H, Kaku CI, Song G, Yuan M, Andrabi R, Burton DR, Walker LM, Wilson IA. Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron. Communications Biology. 5: 766. PMID 35906394 DOI: 10.1038/s42003-022-03700-6 |
0.324 |
|
2022 |
Yuan M, Zhu X, He WT, Zhou P, Kaku CI, Capozzola T, Zhu CY, Yu X, Liu H, Yu W, Hua Y, Tien H, Peng L, Song G, Cottrell CA, ... ... Wilson IA, et al. A broad and potent neutralization epitope in SARS-related coronaviruses. Proceedings of the National Academy of Sciences of the United States of America. 119: e2205784119. PMID 35767670 DOI: 10.1073/pnas.2205784119 |
0.313 |
|
2022 |
Xiang Y, Huang W, Liu H, Sang Z, Nambulli S, Tubiana J, Williams KL, Duprex WP, Schneidman-Duhovny D, Wilson IA, Taylor DJ, Shi Y. Superimmunity by pan-sarbecovirus nanobodies. Cell Reports. 111004. PMID 35738279 DOI: 10.1016/j.celrep.2022.111004 |
0.346 |
|
2022 |
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schäfer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, ... ... Wilson IA, et al. Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses. Nature Immunology. 23: 960-970. PMID 35654851 DOI: 10.1038/s41590-022-01222-1 |
0.306 |
|
2022 |
Torres JL, Ozorowski G, Andreano E, Liu H, Copps J, Piccini G, Donnici L, Conti M, Planchais C, Planas D, Manganaro N, Pantano E, Paciello I, Pileri P, Bruel T, ... ... Wilson IA, et al. Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. Proceedings of the National Academy of Sciences of the United States of America. 119: e2120976119. PMID 35549549 DOI: 10.1073/pnas.2120976119 |
0.333 |
|
2022 |
Beutler N, Pholcharee T, Oyen D, Flores-Garcia Y, MacGill RS, Garcia E, Calla J, Parren M, Yang L, Volkmuth W, Locke E, Regules JA, Dutta S, Emerling D, Early AM, ... ... Wilson IA, et al. A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum. Plos Pathogens. 18: e1010409. PMID 35344575 DOI: 10.1371/journal.ppat.1010409 |
0.303 |
|
2022 |
Cao L, Coventry B, Goreshnik I, Huang B, Park JS, Jude KM, Marković I, Kadam RU, Verschueren KHG, Verstraete K, Walsh STR, Bennett N, Phal A, Yang A, Kozodoy L, ... ... Wilson IA, et al. Design of protein binding proteins from target structure alone. Nature. PMID 35332283 DOI: 10.1038/s41586-022-04654-9 |
0.435 |
|
2022 |
Yuan M, Zhu X, He WT, Zhou P, Kaku CI, Capozzola T, Zhu CY, Yu X, Liu H, Yu W, Hua Y, Tien H, Peng L, Song G, Cottrell CA, ... ... Wilson IA, et al. A broad and potent neutralization epitope in SARS-related coronaviruses. Biorxiv : the Preprint Server For Biology. PMID 35313576 DOI: 10.1101/2022.03.13.484037 |
0.318 |
|
2022 |
Spruit CM, Zhu X, Tomris I, Carrasco MR, Han AX, Broszeit F, van der Woude R, Bouwman KM, Luu MMT, Matsuno K, Sakoda Y, Russell CA, Wilson IA, Boons GJ, de Vries RP. N-glycolylneuraminic acid binding of avian and equine H7 influenza A viruses. Journal of Virology. jvi0212021. PMID 35044215 DOI: 10.1128/jvi.02120-21 |
0.663 |
|
2021 |
Omorodion O, Wilson IA. Structural and Biochemical Characterization of Cysteinylation in Broadly Neutralizing Antibodies to HIV-1. Journal of Molecular Biology. 167303. PMID 34666044 DOI: 10.1016/j.jmb.2021.167303 |
0.309 |
|
2021 |
Kumar S, Lin X, Ngo T, Shapero B, Sou C, Allen JD, Copps J, Zhang L, Ozorowski G, He L, Crispin M, Ward AB, Wilson IA, Zhu J. Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles. Mbio. e0042921. PMID 34156262 DOI: 10.1128/mBio.00429-21 |
0.529 |
|
2021 |
Yuan M, Huang D, Lee CD, Wu NC, Jackson AM, Zhu X, Liu H, Peng L, van Gils MJ, Sanders RW, Burton DR, Reincke SM, Prüss H, Kreye J, Nemazee D, ... ... Wilson IA, et al. Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants. Science (New York, N.Y.). PMID 34016740 DOI: 10.1126/science.abh1139 |
0.308 |
|
2021 |
He L, Chaudhary A, Lin X, Sou C, Alkutkar T, Kumar S, Ngo T, Kosviner E, Ozorowski G, Stanfield RL, Ward AB, Wilson IA, Zhu J. Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines. Nature Communications. 12: 2633. PMID 33976149 DOI: 10.1038/s41467-021-22867-w |
0.515 |
|
2021 |
Zhou X, Ma F, Xie J, Yuan M, Li Y, Shaabani N, Zhao F, Huang D, Wu NC, Lee CD, Liu H, Li J, Chen Z, Hong Y, Liu WH, ... ... Wilson IA, et al. Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2. Cell Reports. 109109. PMID 33932326 DOI: 10.1016/j.celrep.2021.109109 |
0.317 |
|
2021 |
Lee CD, Watanabe Y, Wu NC, Han J, Kumar S, Pholcharee T, Seabright GE, Allen JD, Lin CW, Yang JR, Liu MT, Wu CY, Ward AB, Crispin M, Wilson IA. A cross-neutralizing antibody between HIV-1 and influenza virus. Plos Pathogens. 17: e1009407. PMID 33750987 DOI: 10.1371/journal.ppat.1009407 |
0.539 |
|
2021 |
Pholcharee T, Oyen D, Flores-Garcia Y, Gonzalez-Paez G, Han Z, Williams KL, Volkmuth W, Emerling D, Locke E, Richter King C, Zavala F, Wilson IA. Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum. Nature Communications. 12: 1063. PMID 33594061 DOI: 10.1038/s41467-021-21221-4 |
0.305 |
|
2020 |
Liu H, Wu NC, Yuan M, Bangaru S, Torres JL, Caniels TG, van Schooten J, Zhu X, Lee CD, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity. Immunity. PMID 33242394 DOI: 10.1016/j.immuni.2020.10.023 |
0.339 |
|
2020 |
Wu NC, Yuan M, Liu H, Lee CD, Zhu X, Bangaru S, Torres JL, Caniels TG, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain. Cell Reports. 108274. PMID 33027617 DOI: 10.1016/j.celrep.2020.108274 |
0.306 |
|
2020 |
Kumar S, Ju B, Shapero B, Lin X, Ren L, Zhang L, Li D, Zhou Z, Feng Y, Sou C, Mann CJ, Hao Y, Sarkar A, Hou J, Nunnally C, ... ... Wilson IA, et al. A V1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite. Science Advances. 6. PMID 32938661 DOI: 10.1126/Sciadv.Abb1328 |
0.811 |
|
2020 |
Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, ... ... Wilson IA, et al. Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. Plos Pathogens. 16: e1008753. PMID 32866207 DOI: 10.1371/Journal.Ppat.1008753 |
0.409 |
|
2020 |
Liu H, Wu NC, Yuan M, Bangaru S, Torres JL, Caniels TG, van Schooten J, Zhu X, Lee CD, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity. Biorxiv : the Preprint Server For Biology. PMID 32793906 DOI: 10.1101/2020.08.02.233536 |
0.338 |
|
2020 |
Thai E, Costa G, Weyrich A, Murugan R, Oyen D, Flores-Garcia Y, Prieto K, Bosch A, Valleriani A, Wu NC, Pholcharee T, Scally SW, Wilson IA, Wardemann H, Julien JP, et al. A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity. The Journal of Experimental Medicine. 217. PMID 32790871 DOI: 10.1084/Jem.20200061 |
0.387 |
|
2020 |
Tzarum N, Giang E, Kadam RU, Chen F, Nagy K, Augestad EH, Velázquez-Moctezuma R, Keck ZY, Hua Y, Stanfield RL, Dreux M, Prentoe J, Foung SKH, Bukh J, Wilson IA, et al. An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. Science Advances. 6: eabb5642. PMID 32754640 DOI: 10.1126/Sciadv.Abb5642 |
0.371 |
|
2020 |
Wu NC, Yuan M, Liu H, Lee CD, Zhu X, Bangaru S, Torres JL, Caniels TG, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain. Biorxiv : the Preprint Server For Biology. PMID 32743580 DOI: 10.1101/2020.07.26.222232 |
0.306 |
|
2020 |
Yao Y, Kadam RU, Lee CD, Woehl JL, Wu NC, Zhu X, Kitamura S, Wilson IA, Wolan DW. An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen. Proceedings of the National Academy of Sciences of the United States of America. PMID 32690700 DOI: 10.1073/Pnas.2006893117 |
0.671 |
|
2020 |
Yuan M, Liu H, Wu NC, Lee CD, Zhu X, Zhao F, Huang D, Yu W, Hua Y, Tien H, Rogers TF, Landais E, Sok D, Jardine JG, Burton DR, ... Wilson IA, et al. Structural basis of a shared antibody response to SARS-CoV-2. Science (New York, N.Y.). PMID 32661058 DOI: 10.1126/Science.Abd2321 |
0.45 |
|
2020 |
Yan NL, Santos-Martins D, Rennella E, Sanchez BB, Chen JS, Kay LE, Wilson IA, Morgan GJ, Forli S, Kelly JW. Structural basis for the stabilization of amyloidogenic immunoglobulin light chains by hydantoins. Bioorganic & Medicinal Chemistry Letters. 30: 127356. PMID 32631553 DOI: 10.1016/J.Bmcl.2020.127356 |
0.352 |
|
2020 |
Wu NC, Andrews SF, Raab JE, O'Connell S, Schramm CA, Ding X, Chambers MJ, Leung K, Wang L, Zhang Y, Mascola JR, Douek DC, Ledgerwood JE, McDermott AB, Wilson IA. Convergent Evolution in Breadth of Two V6-1-Encoded Influenza Antibody Clonotypes from a Single Donor. Cell Host & Microbe. PMID 32619441 DOI: 10.1016/J.Chom.2020.06.003 |
0.381 |
|
2020 |
Yuan M, Liu H, Wu NC, Lee CD, Zhu X, Zhao F, Huang D, Yu W, Hua Y, Tien H, Rogers TF, Landais E, Sok D, Jardine JG, Burton DR, ... Wilson IA, et al. Structural basis of a public antibody response to SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 32577642 DOI: 10.1101/2020.06.08.141267 |
0.34 |
|
2020 |
Wu NC, Thompson AJ, Lee JM, Su W, Arlian BM, Xie J, Lerner RA, Yen HL, Bloom JD, Wilson IA. Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses. Science (New York, N.Y.). 368: 1335-1340. PMID 32554590 DOI: 10.1126/Science.Aaz5143 |
0.316 |
|
2020 |
Rogers TF, Zhao F, Huang D, Beutler N, Burns A, He WT, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, ... ... Wilson IA, et al. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model. Science (New York, N.Y.). PMID 32540903 DOI: 10.1126/Science.Abc7520 |
0.383 |
|
2020 |
Stanfield RL, Berndsen ZT, Huang R, Sok D, Warner G, Torres JL, Burton DR, Ward AB, Wilson IA, Smider VV. Structural basis of broad HIV neutralization by a vaccine-induced cow antibody. Science Advances. 6: eaba0468. PMID 32518821 DOI: 10.1126/Sciadv.Aba0468 |
0.427 |
|
2020 |
Meng B, Lan K, Xie J, Lerner RA, Wilson IA, Yang B. Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 32467165 DOI: 10.1073/Pnas.1918844117 |
0.363 |
|
2020 |
Watanabe Y, Berndsen ZT, Raghwani J, Seabright GE, Allen JD, Pybus OG, McLellan JS, Wilson IA, Bowden TA, Ward AB, Crispin M. Vulnerabilities in coronavirus glycan shields despite extensive glycosylation. Nature Communications. 11: 2688. PMID 32461612 DOI: 10.1038/S41467-020-16567-0 |
0.359 |
|
2020 |
Lv H, Wu NC, Tak-Yin Tsang O, Yuan M, Perera RAPM, Leung WS, So RTY, Chun Chan JM, Yip GK, Hong Chik TS, Wang Y, Chung Choi CY, Lin Y, Ng WW, Zhao J, ... ... Wilson IA, et al. Cross-reactive antibody response between SARS-CoV-2 and SARS-CoV infections. Cell Reports. 107725. PMID 32426212 DOI: 10.1016/J.Celrep.2020.107725 |
0.361 |
|
2020 |
Ward AB, Wilson IA. Innovations in structure-based antigen design and immune monitoring for next generation vaccines. Current Opinion in Immunology. 65: 50-56. PMID 32387642 DOI: 10.1016/J.Coi.2020.03.013 |
0.363 |
|
2020 |
Rantalainen K, Berndsen ZT, Antanasijevic A, Schiffner T, Zhang X, Lee WH, Torres JL, Zhang L, Irimia A, Copps J, Zhou KH, Kwon YD, Law WH, Schramm CA, Verardi R, ... ... Wilson IA, et al. HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies. Cell Reports. 31: 107583. PMID 32348769 DOI: 10.1016/J.Celrep.2020.107583 |
0.417 |
|
2020 |
Perera RA, Mok CK, Tsang OT, Lv H, Ko RL, Wu NC, Yuan M, Leung WS, Chan JM, Chik TS, Choi CY, Leung K, Chan KH, Chan KC, Li KC, ... ... Wilson IA, et al. Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020. Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin. 25. PMID 32347204 DOI: 10.2807/1560-7917.Es.2020.25.16.2000421 |
0.31 |
|
2020 |
Yuan M, Wu NC, Zhu X, Lee CD, So RTY, Lv H, Mok CKP, Wilson IA. A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV. Science (New York, N.Y.). PMID 32245784 DOI: 10.1126/Science.Abb7269 |
0.439 |
|
2020 |
Oyen D, Torres JL, Aoto PC, Flores-Garcia Y, Binter S, Pholcharee T, Carroll S, Reponen S, Wash R, Liang Q, Lemiale F, Locke E, Bradley A, King CR, Emerling D, ... ... Wilson IA, et al. Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein. Plos Pathogens. 16: e1008373. PMID 32150583 DOI: 10.1371/Journal.Ppat.1008373 |
0.412 |
|
2020 |
Wu NC, Otwinowski J, Thompson AJ, Nycholat CM, Nourmohammad A, Wilson IA. Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape. Nature Communications. 11: 1233. PMID 32144244 DOI: 10.1038/S41467-020-15102-5 |
0.359 |
|
2020 |
Nguyen DN, Redman RL, Horiya S, Bailey JK, Xu B, Stanfield RL, Temme JS, LaBranche CC, Wang S, Rodal AA, Montefiori DC, Wilson IA, Krauss IJ. The impact of sustained immunization regimens on the antibody response to oligomannose glycans. Acs Chemical Biology. PMID 32109354 DOI: 10.1021/Acschembio.0C00053 |
0.39 |
|
2020 |
Yang YR, McCoy LE, van Gils MJ, Andrabi R, Turner HL, Yuan M, Cottrell CA, Ozorowski G, Voss J, Pauthner M, Polveroni TM, Messmer T, Wilson IA, Sanders RW, Burton DR, et al. Autologous neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened in rabbits. Journal of Virology. PMID 31941772 DOI: 10.1128/Jvi.01861-19 |
0.376 |
|
2019 |
Pholcharee T, Oyen D, Torres JL, Flores-Garcia Y, Martin GM, Gonzalez-Paez G, Emerling D, Volkmuth W, Locke E, King CR, Zavala F, Ward AB, Wilson IA. Diverse antibody responses to conserved structural motifs in Plasmodium falciparum circumsporozoite protein. Journal of Molecular Biology. PMID 31883801 DOI: 10.1016/J.Jmb.2019.12.029 |
0.408 |
|
2019 |
Zost SJ, Lee J, Gumina ME, Parkhouse K, Henry C, Wu NC, Lee CD, Wilson IA, Wilson PC, Bloom JD, Hensley SE. Identification of Antibodies Targeting the H3N2 Hemagglutinin Receptor Binding Site following Vaccination of Humans. Cell Reports. 29: 4460-4470.e8. PMID 31875553 DOI: 10.1016/J.Celrep.2019.11.084 |
0.403 |
|
2019 |
Wu NC, Wilson IA. Influenza Hemagglutinin Structures and Antibody Recognition. Cold Spring Harbor Perspectives in Medicine. PMID 31871236 DOI: 10.1101/Cshperspect.A038778 |
0.401 |
|
2019 |
Ringe RP, Cruz Portillo VM, Dosenovic P, Ketas TJ, Ozorowski G, Nogal B, Perez L, LaBranche CC, Lim J, Francomano E, Wilson IA, Sanders RW, Ward AB, Montefiori DC, Nussenzweig MC, et al. Neutralizing antibody induction by HIV-1 Envelope glycoprotein SOSIP trimers on iron oxide nanoparticles may be impaired by mannose binding lectin. Journal of Virology. PMID 31852794 DOI: 10.1128/Jvi.01883-19 |
0.352 |
|
2019 |
Zhang L, Irimia A, He L, Landais E, Rantalainen K, Leaman DP, Vollbrecht T, Stano A, Sands DI, Kim AS, Poignard P, Burton DR, Murrell B, Ward AB, ... ... Wilson IA, et al. An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nature Communications. 10: 5389. PMID 31772165 DOI: 10.1038/S41467-019-12973-1 |
0.424 |
|
2019 |
Gilchuk IM, Bangaru S, Gilchuk P, Irving RP, Kose N, Bombardi RG, Thornburg NJ, Creech CB, Edwards KM, Li S, Turner HL, Yu W, Zhu X, Wilson IA, Ward AB, et al. Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral Egress and Protect from Lethal Influenza Infection in Mice. Cell Host & Microbe. PMID 31757769 DOI: 10.1016/J.Chom.2019.10.003 |
0.372 |
|
2019 |
Zhu X, Turner HL, Lang S, McBride R, Bangaru S, Gilchuk IM, Yu W, Paulson JC, Crowe JE, Ward AB, Wilson IA. Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host & Microbe. PMID 31757767 DOI: 10.1016/J.Chom.2019.10.002 |
0.412 |
|
2019 |
Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, ... ... Wilson IA, et al. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science (New York, N.Y.). PMID 31672916 DOI: 10.1126/Science.Aax4380 |
0.41 |
|
2019 |
Stadlbauer D, Zhu X, McMahon M, Turner JS, Wohlbold TJ, Schmitz AJ, Strohmeier S, Yu W, Nachbagauer R, Mudd PA, Wilson IA, Ellebedy AH, Krammer F. Broadly protective human antibodies that target the active site of influenza virus neuraminidase. Science (New York, N.Y.). 366: 499-504. PMID 31649200 DOI: 10.1126/Science.Aay0678 |
0.39 |
|
2019 |
Adhikary R, Zimmermann J, Stanfield RL, Wilson IA, Yu W, Oda M, Romesberg FE. Structure and Dynamics of Stacking Interactions in an Antibody Binding Site. Biochemistry. PMID 31243995 DOI: 10.1021/acs.biochem.9b00119 |
0.377 |
|
2019 |
Yuan M, Cottrell CA, Ozorowski G, van Gils MJ, Kumar S, Wu NC, Sarkar A, Torres JL, de Val N, Copps J, Moore JP, Sanders RW, Ward AB, Wilson IA. Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host & Microbe. 25: 873-883.e5. PMID 31194940 DOI: 10.1016/J.Chom.2019.04.011 |
0.813 |
|
2019 |
Broszeit F, Tzarum N, Zhu X, Nemanichvili N, Eggink D, Leenders T, Li Z, Liu L, Wolfert MA, Papanikolaou A, Martínez-Romero C, Gagarinov IA, Yu W, García-Sastre A, Wennekes T, ... ... Wilson IA, et al. N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses. Cell Reports. 27: 3284-3294.e6. PMID 31189111 DOI: 10.1016/J.Celrep.2019.05.048 |
0.657 |
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2019 |
Wu NC, Lv H, Thompson AJ, Wu DC, Ng WWS, Kadam RU, Lin CW, Nycholat CM, McBride R, Liang W, Paulson JC, Mok CKP, Wilson IA. Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility. Cell Host & Microbe. PMID 31151913 DOI: 10.1016/J.Chom.2019.04.013 |
0.301 |
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2019 |
Sliepen K, Han BW, Bontjer I, Mooij P, Garces F, Behrens AJ, Rantalainen K, Kumar S, Sarkar A, Brouwer PJM, Hua Y, Tolazzi M, Schermer E, Torres JL, Ozorowski G, ... ... Wilson IA, et al. Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence. Nature Communications. 10: 2355. PMID 31142746 DOI: 10.1038/S41467-019-10262-5 |
0.817 |
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2019 |
Watanabe Y, Bowden TA, Wilson IA, Crispin M. Exploitation of glycosylation in enveloped virus pathobiology. Biochimica Et Biophysica Acta. General Subjects. PMID 31121217 DOI: 10.1016/J.Bbagen.2019.05.012 |
0.341 |
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2019 |
Andrabi R, Pallesen J, Allen JD, Song G, Zhang J, de Val N, Gegg G, Porter K, Su CY, Pauthner M, Newman A, Bouton-Verville H, Garces F, Wilson IA, Crispin M, et al. The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template. Cell Reports. 27: 2426-2441.e6. PMID 31116986 DOI: 10.1016/J.Celrep.2019.04.082 |
0.37 |
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2019 |
Bangaru S, Lang S, Schotsaert M, Vanderven HA, Zhu X, Kose N, Bombardi R, Finn JA, Kent SJ, Gilchuk P, Gilchuk I, Turner HL, García-Sastre A, Li S, Ward AB, ... Wilson IA, et al. A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface. Cell. 177: 1136-1152.e18. PMID 31100268 DOI: 10.1016/J.Cell.2019.04.011 |
0.353 |
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2019 |
Hong S, Shi Y, Wu NC, Grande G, Douthit L, Wang H, Zhou W, Sharpless KB, Wilson IA, Xie J, Wu P. Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification. Nature Communications. 10: 1799. PMID 30996301 DOI: 10.1038/S41467-019-09608-W |
0.306 |
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2019 |
Xia S, Yan L, Xu W, Agrawal AS, Algaissi A, Tseng CK, Wang Q, Du L, Tan W, Wilson IA, Jiang S, Yang B, Lu L. A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Science Advances. 5: eaav4580. PMID 30989115 DOI: 10.1126/Sciadv.Aav4580 |
0.349 |
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2019 |
Morgan GJ, Yan NL, Mortenson DE, Rennella E, Blundon JM, Gwin RM, Lin CY, Stanfield RL, Brown SJ, Rosen H, Spicer TP, Fernandez-Vega V, Merlini G, Kay LE, Wilson IA, et al. Stabilization of amyloidogenic immunoglobulin light chains by small molecules. Proceedings of the National Academy of Sciences of the United States of America. PMID 30971495 DOI: 10.1073/Pnas.1817567116 |
0.335 |
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2019 |
Murin CD, Wilson IA, Ward AB. Antibody responses to viral infections: a structural perspective across three different enveloped viruses. Nature Microbiology. PMID 30886356 DOI: 10.1038/S41564-019-0392-Y |
0.392 |
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2019 |
Chen F, Tzarum N, Wilson IA, Law M. V1-69 antiviral broadly neutralizing antibodies: genetics, structures, and relevance to rational vaccine design. Current Opinion in Virology. 34: 149-159. PMID 30884330 DOI: 10.1016/J.Coviro.2019.02.004 |
0.413 |
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2019 |
van Dongen MJP, Kadam RU, Juraszek J, Lawson E, Brandenburg B, Schmitz F, Schepens WBG, Stoops B, van Diepen HA, Jongeneelen M, Tang C, Vermond J, van Eijgen-Obregoso Real A, Blokland S, Garg D, ... ... Wilson IA, et al. A small-molecule fusion inhibitor of influenza virus is orally active in mice. Science (New York, N.Y.). 363. PMID 30846569 DOI: 10.1126/Science.Aar6221 |
0.362 |
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2019 |
Nguyen DN, Xu B, Stanfield RL, Bailey JK, Horiya S, Temme JS, Leon DR, LaBranche CC, Montefiori DC, Costello CE, Wilson IA, Krauss IJ. Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities. Acs Central Science. 5: 237-249. PMID 30834312 DOI: 10.1021/Acscentsci.8B00588 |
0.433 |
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2019 |
Kumar S, Sarkar A, Pugach P, Sanders RW, Moore JP, Ward AB, Wilson IA. Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide. Nature Communications. 10: 763. PMID 30770829 DOI: 10.1038/s41467-019-08738-5 |
0.805 |
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2019 |
de Taeye SW, Go EP, Sliepen K, Torrents de la Peña A, Badal K, Medina-Ramirez M, Lee WH, Desaire H, Wilson IA, Moore JP, Ward AB, Sanders RW. Stabilization of the V2 loop improves the presentation of V2 loop-associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers. The Journal of Biological Chemistry. PMID 30728245 DOI: 10.1074/Jbc.Ra118.005396 |
0.389 |
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2019 |
Turner HL, Pallesen J, Lang S, Bangaru S, Urata S, Li S, Cottrell CA, Bowman CA, Crowe JE, Wilson IA, Ward AB. Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains. Plos Biology. 17: e3000139. PMID 30716060 DOI: 10.1371/Journal.Pbio.3000139 |
0.418 |
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2019 |
Sevy AM, Wu NC, Gilchuk IM, Parrish EH, Burger S, Yousif D, Nagel MBM, Schey KL, Wilson IA, Crowe JE, Meiler J. Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 30642961 DOI: 10.1073/pnas.1806004116 |
0.41 |
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2019 |
Tzarum N, Giang E, Kong L, He L, Prentoe J, Augestad E, Hua Y, Castillo S, Lauer GM, Bukh J, Zhu J, Wilson IA, Law M. Genetic and structural insights into broad neutralization of hepatitis C virus by human V1-69 antibodies. Science Advances. 5: eaav1882. PMID 30613781 DOI: 10.1126/Sciadv.Aav1882 |
0.332 |
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2019 |
Kumar S, Sarkar A, Pugach P, Sanders RW, Moore JP, Ward AB, Wilson IA. Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide. Nature Communications. 10: 763-763. DOI: 10.2210/Pdb6Mco/Pdb |
0.81 |
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2018 |
Pauthner MG, Nkolola JP, Havenar-Daughton C, Murrell B, Reiss SM, Bastidas R, Prévost J, Nedellec R, von Bredow B, Abbink P, Cottrell CA, Kulp DW, Tokatlian T, Nogal B, Bianchi M, ... ... Wilson IA, et al. Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers. Immunity. PMID 30552025 DOI: 10.1016/J.Immuni.2018.11.011 |
0.373 |
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2018 |
Zost SJ, Wu NC, Hensley SE, Wilson IA. Immunodominance and antigenic variation of influenza virus hemagglutinin: implications for design of universal vaccine immunogens. The Journal of Infectious Diseases. PMID 30535315 DOI: 10.1093/Infdis/Jiy696 |
0.407 |
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2018 |
Ringe RP, Pugach P, Cottrell CA, LaBranche CC, Seabright GE, Ketas TJ, Ozorowski G, Kumar S, Schorcht A, van Gils MJ, Crispin M, Montefiori DC, Wilson IA, Ward AB, Sanders RW, et al. Closing and opening holes in the glycan shield of HIV-1 envelope glycoprotein SOSIP trimers can redirect the neutralizing antibody response to the newly unmasked epitopes. Journal of Virology. PMID 30487280 DOI: 10.1128/Jvi.01656-18 |
0.609 |
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2018 |
He L, Kumar S, Allen JD, Huang D, Lin X, Mann CJ, Saye-Francisco KL, Copps J, Sarkar A, Blizard GS, Ozorowski G, Sok D, Crispin M, Ward AB, Nemazee D, ... ... Wilson IA, et al. HIV-1 vaccine design through minimizing envelope metastability. Science Advances. 4: eaau6769. PMID 30474059 DOI: 10.1126/Sciadv.Aau6769 |
0.792 |
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2018 |
Laursen NS, Friesen RHE, Zhu X, Jongeneelen M, Blokland S, Vermond J, van Eijgen A, Tang C, van Diepen H, Obmolova G, van der Neut Kolfschoten M, Zuijdgeest D, Straetemans R, Hoffman RMB, Nieusma T, ... ... Wilson IA, et al. Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science (New York, N.Y.). 362: 598-602. PMID 30385580 DOI: 10.1126/Science.Aaq0620 |
0.392 |
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2018 |
Credille CV, Dick B, Morrison CN, Stokes RW, Adamek R, Wu NC, Wilson IA, Cohen SM. Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease. Journal of Medicinal Chemistry. PMID 30351002 DOI: 10.1021/acs.jmedchem.8b01363 |
0.316 |
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2018 |
Oyen D, Torres JL, Cottrell CA, Richter King C, Wilson IA, Ward AB. Cryo-EM structure of circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts. Science Advances. 4: eaau8529. PMID 30324137 DOI: 10.1126/sciadv.aau8529 |
0.3 |
|
2018 |
Zhang H, Zhu X, Pascual G, Wadia JS, Keogh E, Hoozemans JJ, Siregar B, Inganäs H, Stoop EJM, Goudsmit J, Apetri A, Koudstaal W, Wilson IA. Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody. Structure (London, England : 1993). PMID 30318466 DOI: 10.1016/J.Str.2018.08.012 |
0.349 |
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2018 |
Wu NC, Yamayoshi S, Ito M, Uraki R, Kawaoka Y, Wilson IA. Recurring and Adaptable Binding Motifs in Broadly Neutralizing Antibodies to Influenza Virus Are Encoded on the D3-9 Segment of the Ig Gene. Cell Host & Microbe. 24: 569-578.e4. PMID 30308159 DOI: 10.1016/J.Chom.2018.09.010 |
0.357 |
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2018 |
Yang K, Stanfield RL, Martinez-Yamout MA, Dyson HJ, Wilson IA, Wright PE. Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 30232260 DOI: 10.1073/pnas.1810397115 |
0.352 |
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2018 |
Yan L, Meng B, Xiang J, Wilson IA, Yang B. Crystal structure of the post-fusion core of the Human coronavirus 229E spike protein at 1.86 Å resolution. Acta Crystallographica. Section D, Structural Biology. 74: 841-851. PMID 30198895 DOI: 10.1107/S2059798318008318 |
0.368 |
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2018 |
Bianchi M, Turner HL, Nogal B, Cottrell CA, Oyen D, Pauthner M, Bastidas R, Nedellec R, McCoy LE, Wilson IA, Burton DR, Ward AB, Hangartner L. Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization. Immunity. PMID 30097292 DOI: 10.1016/J.Immuni.2018.07.009 |
0.376 |
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2018 |
Bangaru S, Zhang H, Gilchuk IM, Voss TG, Irving RP, Gilchuk P, Matta P, Zhu X, Lang S, Nieusma T, Richt JA, Albrecht RA, Vanderven HA, Bombardi R, Kent SJ, ... ... Wilson IA, et al. A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nature Communications. 9: 2669. PMID 29991715 DOI: 10.1038/S41467-018-04704-9 |
0.412 |
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2018 |
Havenar-Daughton C, Sarkar A, Kulp DW, Toy L, Hu X, Deresa I, Kalyuzhniy O, Kaushik K, Upadhyay AA, Menis S, Landais E, Cao L, Diedrich JK, Kumar S, Schiffner T, ... ... Wilson IA, et al. The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen. Science Translational Medicine. 10. PMID 29973404 DOI: 10.1126/Scitranslmed.Aat0381 |
0.784 |
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2018 |
Aleman F, Tzarum N, Kong L, Nagy K, Zhu J, Wilson IA, Law M. Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors. Proceedings of the National Academy of Sciences of the United States of America. PMID 29954862 DOI: 10.1073/Pnas.1802378115 |
0.362 |
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2018 |
Tzarum N, Wilson IA, Law M. The Neutralizing Face of Hepatitis C Virus E2 Envelope Glycoprotein. Frontiers in Immunology. 9: 1315. PMID 29951061 DOI: 10.3389/Fimmu.2018.01315 |
0.385 |
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2018 |
Rantalainen K, Berndsen ZT, Murrell S, Cao L, Omorodion O, Torres JL, Wu M, Umotoy J, Copps J, Poignard P, Landais E, Paulson JC, Wilson IA, Ward AB. Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design. Cell Reports. 23: 3249-3261. PMID 29898396 DOI: 10.1016/J.Celrep.2018.05.046 |
0.418 |
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2018 |
Oyen D, Torres JL, Wille-Reece U, Ockenhouse CF, Emerling D, Glanville J, Volkmuth W, Flores-Garcia Y, Zavala F, Ward AB, King CR, Wilson IA. Erratum: Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein (Proceedings of the National Academy of Sciences of the United States of America (2017) 114 (E10438–E10445) DOI: 10.1073/pnas.1715812114) Proceedings of the National Academy of Sciences of the United States of America. 115. PMID 29891667 DOI: 10.1073/Pnas.1808460115 |
0.335 |
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2018 |
Apetri A, Crespo R, Juraszek J, Pascual G, Janson R, Zhu X, Zhang H, Keogh E, Holland T, Wadia J, Verveen H, Siregar B, Mrosek M, Taggenbrock R, Ameijde J, ... ... Wilson IA, et al. A common antigenic motif recognized by naturally occurring human V5-51/V4-1 anti-tau antibodies with distinct functionalities. Acta Neuropathologica Communications. 6: 43. PMID 29855358 DOI: 10.1186/S40478-018-0543-Z |
0.361 |
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2018 |
Sarkar A, Bale S, Behrens AJ, Kumar S, Sharma SK, de Val N, Pallesen J, Irimia A, Diwanji DC, Stanfield RL, Ward AB, Crispin M, Wyatt RT, Wilson IA. Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer. Nature Communications. 9: 1956. PMID 29769533 DOI: 10.1038/S41467-018-04272-Y |
0.82 |
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2018 |
Kadam RU, Wilson IA. A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin. Proceedings of the National Academy of Sciences of the United States of America. PMID 29610325 DOI: 10.2210/Pdb6Cf5/Pdb |
0.402 |
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2018 |
Gunn RJ, Herrin BR, Acharya S, Cooper MD, Wilson IA. VLR recognition of TLR5 expands the molecular characterization of protein antigen binding by non-Ig-based antibodies. Journal of Molecular Biology. PMID 29596914 DOI: 10.1016/J.Jmb.2018.03.016 |
0.408 |
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2018 |
Crispin M, Ward AB, Wilson IA. Structure and Immune Recognition of the HIV Glycan Shield. Annual Review of Biophysics. PMID 29595997 DOI: 10.1146/Annurev-Biophys-060414-034156 |
0.418 |
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2018 |
Wu NC, Thompson AJ, Xie J, Lin CW, Nycholat CM, Zhu X, Lerner RA, Paulson JC, Wilson IA. A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nature Communications. 9: 1264. PMID 29593268 DOI: 10.1038/S41467-018-03663-5 |
0.363 |
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2018 |
Tan J, Sack BK, Oyen D, Zenklusen I, Piccoli L, Barbieri S, Foglierini M, Fregni CS, Marcandalli J, Jongo S, Abdulla S, Perez L, Corradin G, Varani L, Sallusto F, ... ... Wilson IA, et al. A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein. Nature Medicine. PMID 29554084 DOI: 10.1038/Nm.4513 |
0.407 |
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2018 |
Klasse PJ, Ketas TJ, Cottrell CA, Ozorowski G, Debnath G, Camara D, Francomano E, Pugach P, Ringe RP, LaBranche CC, van Gils MJ, Bricault CA, Barouch DH, Crotty S, Silvestri G, ... ... Wilson IA, et al. Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques. Plos Pathogens. 14: e1006913. PMID 29474444 DOI: 10.1371/Journal.Ppat.1006913 |
0.417 |
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2018 |
Stanfield RL, Haakenson J, Deiss TC, Criscitiello MF, Wilson IA, Smider VV. The Unusual Genetics and Biochemistry of Bovine Immunoglobulins. Advances in Immunology. 137: 135-164. PMID 29455846 DOI: 10.1016/Bs.Ai.2017.12.004 |
0.403 |
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2018 |
Behrens AJ, Kumar A, Medina-Ramirez M, Cupo A, Marshall K, Cruz Portillo VM, Harvey DJ, Ozorowski G, Zitzmann N, Wilson IA, Ward AB, Struwe WB, Moore JP, Sanders RW, Crispin M. Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages. Journal of Proteome Research. PMID 29420040 DOI: 10.1021/Acs.Jproteome.7B00639 |
0.368 |
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2018 |
Wu NC, Wilson IA. Structural insights into the design of novel anti-influenza therapies. Nature Structural & Molecular Biology. PMID 29396418 DOI: 10.1038/S41594-018-0025-9 |
0.383 |
|
2018 |
Oyen D, Torres JL, Cottrell CA, King CR, Wilson IA, Ward AB. Cryo-EM structure ofP. falciparumcircumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts. Science Advances. 4. DOI: 10.2210/Pdb6Mhg/Pdb |
0.413 |
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2018 |
Wu NC, Yamayoshi S, Ito M, Uraki R, Kawaoka Y, Wilson IA. The D3-9 gene segment encodes for recurring and adaptable binding motifs in broadly neutralizing antibodies to influenza virus Cell Host & Microbe. DOI: 10.2210/Pdb6E3H/Pdb |
0.353 |
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2018 |
Wilson IA. Structure-assisted design of universal vaccines and therapeutics against influenza virus Acta Crystallographica Section a Foundations and Advances. 74: a114-a114. DOI: 10.1107/S0108767318098859 |
0.321 |
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2018 |
Stanfield RL, Nguyen DN, Krauss IJ, Wilson IA. Synthetic glycopeptide selected by directed evolution in complex with anti-HIV-1 Fab 2G12 Acta Crystallographica Section a Foundations and Advances. 74: a178-a178. DOI: 10.1107/S0108767318098215 |
0.303 |
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2017 |
Mortenson DE, Brighty GJ, Plate L, Bare G, Chen W, Li S, Wang H, Cravatt BF, Forli S, Powers ET, Sharpless KB, Wilson IA, Kelly JW. "Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates. Journal of the American Chemical Society. PMID 29265822 DOI: 10.1021/Jacs.7B08366 |
0.313 |
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2017 |
Gopal R, Jackson K, Tzarum N, Kong L, Ettenger A, Guest J, Pfaff JM, Barnes T, Honda A, Giang E, Davidson E, Wilson IA, Doranz BJ, Law M. Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis. Plos Pathogens. 13: e1006735. PMID 29253863 DOI: 10.1371/Journal.Ppat.1006735 |
0.376 |
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2017 |
de Taeye SW, Torrents de la Peña A, Vecchione A, Scutigliani E, Sliepen K, Burger JA, van der Woude P, Schorcht A, Schermer EE, van Gils MJ, LaBranche CC, Montefiori DC, Wilson IA, Moore JP, Ward AB, et al. Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers. The Journal of Biological Chemistry. PMID 29222332 DOI: 10.1074/Jbc.Ra117.000709 |
0.375 |
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2017 |
Collins BC, Nakahara H, Acharya S, Cooper MD, Herrin BR, Wilson IA. Crystal structure of an anti-idiotype variable lymphocyte receptor. Acta Crystallographica. Section F, Structural Biology Communications. 73: 682-687. PMID 29199989 DOI: 10.1107/S2053230X1701620X |
0.412 |
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2017 |
Landais E, Murrell B, Briney B, Murrell S, Rantalainen K, Berndsen ZT, Ramos A, Wickramasinghe L, Smith ML, Eren K, de Val N, Wu M, Cappelletti A, Umotoy J, Lie Y, ... ... Wilson IA, et al. HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage. Immunity. 47: 990-1003.e9. PMID 29166592 DOI: 10.1016/J.Immuni.2017.11.002 |
0.389 |
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2017 |
Dey AK, Cupo A, Ozorowski G, Sharma VK, Behrens AJ, Go EP, Ketas TJ, Yasmeen A, Klasse PJ, Sayeed E, Desaire H, Crispin M, Wilson IA, Sanders RW, Hassell T, et al. cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate. Biotechnology and Bioengineering. PMID 29150937 DOI: 10.1002/Bit.26498 |
0.378 |
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2017 |
Pantophlet R, Trattnig N, Murrell S, Lu N, Chau D, Rempel C, Wilson IA, Kosma P. Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity. Nature Communications. 8: 1601. PMID 29150603 DOI: 10.1038/S41467-017-01640-Y |
0.424 |
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2017 |
Oyen D, Torres JL, Wille-Reece U, Ockenhouse CF, Emerling D, Glanville J, Volkmuth W, Flores-Garcia Y, Zavala F, Ward AB, King CR, Wilson IA. Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein. Proceedings of the National Academy of Sciences of the United States of America. PMID 29138320 DOI: 10.1073/Pnas.1715812114 |
0.42 |
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2017 |
Wu NC, Zost SJ, Thompson AJ, Oyen D, Nycholat CM, McBride R, Paulson JC, Hensley SE, Wilson IA. A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. Plos Pathogens. 13: e1006682. PMID 29059230 DOI: 10.1371/Journal.Ppat.1006682 |
0.382 |
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2017 |
Collins BC, Gunn RJ, McKitrick TR, Cummings RD, Cooper MD, Herrin BR, Wilson IA. Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates. Structure (London, England : 1993). PMID 28988747 DOI: 10.1016/J.Str.2017.09.003 |
0.372 |
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2017 |
Voss JE, Andrabi R, McCoy LE, de Val N, Fuller RP, Messmer T, Su CY, Sok D, Khan SN, Garces F, Pritchard LK, Wyatt RT, Ward AB, Crispin M, Wilson IA, et al. Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model. Cell Reports. 21: 222-235. PMID 28978475 DOI: 10.1016/J.Celrep.2017.09.024 |
0.405 |
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2017 |
Kadam RU, Juraszek J, Brandenburg B, Buyck C, Schepens WBG, Kesteleyn B, Stoops B, Vreeken R, Vermond J, Goutier W, Tang C, Vogels R, Friesen RHE, Goudsmit J, van Dongen MJP, ... Wilson IA, et al. Potent peptidic fusion inhibitors of influenza virus. Science (New York, N.Y.). PMID 28971971 DOI: 10.1126/Science.Aan0516 |
0.346 |
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2017 |
Chevalier A, Silva DA, Rocklin GJ, Hicks DR, Vergara R, Murapa P, Bernard SM, Zhang L, Lam KH, Yao G, Bahl CD, Miyashita SI, Goreshnik I, Fuller JT, Koday MT, ... ... Wilson IA, et al. Massively parallel de novo protein design for targeted therapeutics. Nature. PMID 28953867 DOI: 10.1038/Nature23912 |
0.335 |
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2017 |
Lang S, Xie J, Zhu X, Wu NC, Lerner RA, Wilson IA. Antibody 27F3 Broadly Targets Influenza A Group 1 and 2 Hemagglutinins through a Further Variation in VH1-69 Antibody Orientation on the HA Stem. Cell Reports. 20: 2935-2943. PMID 28930686 DOI: 10.1016/J.Celrep.2017.08.084 |
0.365 |
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2017 |
Medina-Ramírez M, Garces F, Escolano A, Skog P, de Taeye SW, Del Moral-Sanchez I, McGuire AT, Yasmeen A, Behrens AJ, Ozorowski G, van den Kerkhof TLGM, Freund NT, Dosenovic P, Hua Y, Gitlin AD, ... ... Wilson IA, et al. Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. The Journal of Experimental Medicine. PMID 28847869 DOI: 10.1084/Jem.20161160 |
0.471 |
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2017 |
Torrents de la Peña A, Julien JP, de Taeye SW, Garces F, Guttman M, Ozorowski G, Pritchard LK, Behrens AJ, Go EP, Burger JA, Schermer EE, Sliepen K, Ketas TJ, Pugach P, Yasmeen A, ... ... Wilson IA, et al. Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization. Cell Reports. 20: 1805-1817. PMID 28834745 DOI: 10.1016/J.Celrep.2017.07.077 |
0.414 |
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2017 |
Koch K, Kalusche S, Torres JL, Stanfield RL, Danquah W, Khazanehdari K, von Briesen H, Geertsma ER, Wilson IA, Wernery U, Koch-Nolte F, Ward AB, Dietrich U. Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers. Scientific Reports. 7: 8390. PMID 28827559 DOI: 10.1038/S41598-017-08273-7 |
0.382 |
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2017 |
Wu NC, Xie J, Zheng T, Nycholat CM, Grande G, Paulson JC, Lerner RA, Wilson IA. Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin. Cell Host & Microbe. 22: 247-248. PMID 28799910 DOI: 10.1016/J.Chom.2017.07.001 |
0.322 |
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2017 |
Sok D, Le KM, Vadnais M, Saye-Francisco K, Jardine JG, Torres J, Berndsen ZT, Kong L, Stanfield R, Ruiz J, Ramos A, Liang CH, Chen PL, Criscitiello MF, Mwangi W, ... Wilson IA, et al. Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows. Nature. PMID 28726771 DOI: 10.1038/Nature23301 |
0.389 |
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2017 |
Ozorowski G, Pallesen J, de Val N, Lyumkis D, Cottrell CA, Torres JL, Copps J, Stanfield RL, Cupo A, Pugach P, Moore JP, Wilson IA, Ward AB. Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike. Nature. PMID 28700571 DOI: 10.1038/Nature23010 |
0.437 |
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2017 |
de Vries RP, Tzarum N, Peng W, Thompson AJ, Ambepitiya Wickramasinghe IN, de la Pena ATT, van Breemen MJ, Bouwman KM, Zhu X, McBride R, Yu W, Sanders RW, Verheije MH, Wilson IA, Paulson JC. A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors. Embo Molecular Medicine. PMID 28694323 DOI: 10.15252/Emmm.201707726 |
0.68 |
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2017 |
Wright ZVF, Wu NC, Kadam RU, Wilson IA, Wolan DW. Structure-based optimization and synthesis of antiviral drug Arbidol analogues with significantly improved affinity to influenza hemagglutinin. Bioorganic & Medicinal Chemistry Letters. PMID 28689973 DOI: 10.1016/J.Bmcl.2017.06.074 |
0.676 |
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2017 |
Wu NC, Wilson IA. A perspective on the structural and functional constraints for immune evasion: Insights from the influenza virus. Journal of Molecular Biology. PMID 28648617 DOI: 10.1016/J.Jmb.2017.06.015 |
0.386 |
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2017 |
Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, ... ... Wilson IA, et al. Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches. Immunity. 46: 1073-1088.e6. PMID 28636956 DOI: 10.1016/J.Immuni.2017.05.007 |
0.347 |
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2017 |
Park S, Stanfield RL, Martinez-Yamout MA, Dyson HJ, Wilson IA, Wright PE. Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630323 DOI: 10.1073/Pnas.1703105114 |
0.318 |
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2017 |
Connelly S, Mortenson DE, Choi S, Wilson IA, Powers ET, Kelly JW, Johnson SM. Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 28625364 DOI: 10.1016/J.Bmcl.2017.05.080 |
0.312 |
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2017 |
Wu NC, Xie J, Zheng T, Nycholat CM, Grande G, Paulson JC, Lerner RA, Wilson IA. Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin. Cell Host & Microbe. 21: 742-753.e8. PMID 28618270 DOI: 10.1016/J.Chom.2017.05.011 |
0.365 |
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2017 |
de Vries RP, Peng W, Grant OC, Thompson AJ, Zhu X, Bouwman KM, de la Pena ATT, van Breemen MJ, Ambepitiya Wickramasinghe IN, de Haan CAM, Yu W, McBride R, Sanders RW, Woods RJ, Verheije MH, ... Wilson IA, et al. Three mutations switch H7N9 influenza to human-type receptor specificity. Plos Pathogens. 13: e1006390. PMID 28617868 DOI: 10.1371/Journal.Ppat.1006390 |
0.659 |
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2017 |
Luo X, Fu G, Wang RE, Zhu X, Zambaldo C, Liu R, Liu T, Lyu X, Du J, Xuan W, Yao A, Reed SA, Kang M, Zhang Y, Guo H, ... ... Wilson IA, et al. Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria. Nature Chemical Biology. PMID 28604693 DOI: 10.1038/Nchembio.2405 |
0.329 |
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2017 |
Strauch EM, Bernard SM, La D, Bohn AJ, Lee PS, Anderson CE, Nieusma T, Holstein CA, Garcia NK, Hooper KA, Ravichandran R, Nelson JW, Sheffler W, Bloom JD, Lee KK, ... ... Wilson IA, et al. Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site. Nature Biotechnology. PMID 28604661 DOI: 10.1038/Nbt.3907 |
0.368 |
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2017 |
Ringe RP, Ozorowski G, Rantalainen K, Struwe WB, Matthews K, Torres JL, Yasmeen A, Cottrell CA, Ketas TJ, LaBranche CC, Montefiori DC, Cupo A, Crispin M, Wilson IA, Ward AB, et al. Reducing V3 antigenicity and immunogenicity on soluble, native-like HIV-1 Env SOSIP trimers. Journal of Virology. PMID 28539451 DOI: 10.1128/Jvi.00677-17 |
0.429 |
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2017 |
Guenaga J, Garces F, de Val N, Stanfield RL, Dubrovskaya V, Higgins B, Carrette B, Ward AB, Wilson IA, Wyatt RT. Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein. Immunity. 46: 792-803.e3. PMID 28514686 DOI: 10.1016/J.Immuni.2017.04.014 |
0.419 |
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2017 |
Wu NC, Grande G, Turner HL, Ward AB, Xie J, Lerner RA, Wilson IA. In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity. Nature Communications. 8: 15371. PMID 28504265 DOI: 10.1038/Ncomms15371 |
0.4 |
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2017 |
Lee JH, Andrabi R, Su CY, Yasmeen A, Julien JP, Kong L, Wu NC, McBride R, Sok D, Pauthner M, Cottrell CA, Nieusma T, Blattner C, Paulson JC, Klasse PJ, ... Wilson IA, et al. A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure. Immunity. 46: 690-702. PMID 28423342 DOI: 10.1016/J.Immuni.2017.03.017 |
0.441 |
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2017 |
Tzarum N, McBride R, Nycholat CM, Paulson JC, Wilson IA. Unique structural features of influenza H15 HA. Journal of Virology. PMID 28404848 DOI: 10.1128/Jvi.00046-17 |
0.307 |
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2017 |
Tzarum N, de Vries RP, Peng W, Thompson AJ, Bouwman KM, McBride R, Yu W, Zhu X, Verheije MH, Paulson JC, Wilson IA. The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus. Cell Reports. 19: 235-245. PMID 28402848 DOI: 10.1016/J.Celrep.2017.03.054 |
0.673 |
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2017 |
Ringe RP, Ozorowski G, Yasmeen A, Cupo A, Cruz Portillo VM, Pugach P, Golabek M, Rantalainen K, Holden LG, Cottrell CA, Wilson IA, Sanders RW, Ward AB, Klasse PJ, Moore JP. Improving the expression and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers by targeted sequence changes. Journal of Virology. PMID 28381572 DOI: 10.1128/Jvi.00264-17 |
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2017 |
Pascual G, Wadia JS, Zhu X, Keogh E, Kükrer B, van Ameijde J, Inganäs H, Siregar B, Perdok G, Diefenbach O, Nahar T, Sprengers I, Koldijk MH, der Linden EC, Peferoen LA, ... ... Wilson IA, et al. Immunological memory to hyperphosphorylated tau in asymptomatic individuals. Acta Neuropathologica. PMID 28341999 DOI: 10.1007/S00401-017-1705-Y |
0.363 |
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2017 |
Polonskaya Z, Deng S, Sarkar A, Kain L, Comellas-Aragones M, McKay CS, Kaczanowska K, Holt M, McBride R, Palomo V, Self KM, Taylor S, Irimia A, Mehta SR, Dan JM, ... ... Wilson IA, et al. T cells control the generation of nanomolar-affinity anti-glycan antibodies. The Journal of Clinical Investigation. PMID 28287405 DOI: 10.1172/Jci91192 |
0.746 |
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2017 |
Irimia A, Serra AM, Sarkar A, Jacak R, Kalyuzhniy O, Sok D, Saye-Francisco KL, Schiffner T, Tingle R, Kubitz M, Adachi Y, Stanfield RL, Deller MC, Burton DR, Schief WR, ... Wilson IA, et al. Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design. Plos Pathogens. 13: e1006212. PMID 28225819 DOI: 10.1371/Journal.Ppat.1006212 |
0.752 |
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2017 |
Ward AB, Wilson IA. The HIV-1 envelope glycoprotein structure: nailing down a moving target. Immunological Reviews. 275: 21-32. PMID 28133813 DOI: 10.1111/Imr.12507 |
0.456 |
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2016 |
Peng W, de Vries RP, Grant OC, Thompson AJ, McBride R, Tsogtbaatar B, Lee PS, Razi N, Wilson IA, Woods RJ, Paulson JC. Recent H3N2 Viruses Have Evolved Specificity for Extended, Branched Human-type Receptors, Conferring Potential for Increased Avidity. Cell Host & Microbe. PMID 28017661 DOI: 10.1016/J.Chom.2016.11.004 |
0.664 |
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2016 |
Kadam RU, Wilson IA. Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol. Proceedings of the National Academy of Sciences of the United States of America. PMID 28003465 DOI: 10.1073/Pnas.1617020114 |
0.391 |
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2016 |
van Gils MJ, van den Kerkhof TL, Ozorowski G, Cottrell CA, Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye SW, Schorcht A, Gumbs S, Johanna I, Saye-Francisco K, Liang CH, ... ... Wilson IA, et al. An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability. Nature Microbiology. 2: 16199. PMID 27841852 DOI: 10.1038/Nmicrobiol.2016.199 |
0.424 |
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2016 |
Kong L, Lee DE, Kadam RU, Liu T, Giang E, Nieusma T, Garces F, Tzarum N, Woods VL, Ward AB, Li S, Wilson IA, Law M. Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791120 DOI: 10.1073/Pnas.1609780113 |
0.341 |
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2016 |
Das N, Dewan V, Grace PM, Gunn RJ, Tamura R, Tzarum N, Watkins LR, Wilson IA, Yin H. HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia. Cell Reports. 17: 1128-1140. PMID 27760316 DOI: 10.1016/J.Celrep.2016.09.076 |
0.497 |
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2016 |
Jardine JG, Sok D, Julien JP, Briney B, Sarkar A, Liang CH, Scherer EM, Henry Dunand CJ, Adachi Y, Diwanji D, Hsueh J, Jones M, Kalyuzhniy O, Kubitz M, Spencer S, ... ... Wilson IA, et al. Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. Plos Pathogens. 12: e1005905. PMID 27627763 DOI: 10.1371/Journal.Ppat.1005905 |
0.746 |
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2016 |
Klasse PJ, LaBranche CC, Ketas TJ, Ozorowski G, Cupo A, Pugach P, Ringe RP, Golabek M, van Gils MJ, Guttman M, Lee KK, Wilson IA, Butera ST, Ward AB, Montefiori DC, et al. Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C. Plos Pathogens. 12: e1005864. PMID 27627672 DOI: 10.1371/Journal.Ppat.1005864 |
0.347 |
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2016 |
Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O, Briney B, Schiffner T, Garces F, Freund NT, Gitlin AD, ... ... Wilson IA, et al. HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies. Immunity. PMID 27617678 DOI: 10.1016/J.Immuni.2016.08.016 |
0.387 |
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2016 |
Briney B, Sok D, Jardine JG, Kulp DW, Skog P, Menis S, Jacak R, Kalyuzhniy O, de Val N, Sesterhenn F, Le KM, Ramos A, Jones M, Saye-Francisco KL, Blane TR, ... ... Wilson IA, et al. Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies. Cell. 166: 1459-1470.e11. PMID 27610570 DOI: 10.1016/J.Cell.2016.08.005 |
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2016 |
Stanfield RL, Wilson IA, Smider VV. Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies. Science Immunology. 1. PMID 27574710 DOI: 10.1126/Sciimmunol.Aaf7962 |
0.381 |
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2016 |
Jardine JG, Sok D, Julien JP, Briney B, Sarkar A, Liang CH, Scherer EA, Henry Dunand CJ, Adachi Y, Diwanji D, Hsueh J, Jones M, Kalyuzhniy O, Kubitz M, Spencer S, ... ... Wilson IA, et al. Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. Plos Pathogens. 12: e1005815. PMID 27560183 DOI: 10.1371/Journal.Ppat.1005815 |
0.758 |
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2016 |
McCoy LE, van Gils MJ, Ozorowski G, Messmer T, Briney B, Voss JE, Kulp DW, Macauley MS, Sok D, Pauthner M, Menis S, Cottrell CA, Torres JL, Hsueh J, Schief WR, ... Wilson IA, et al. Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies. Cell Reports. PMID 27545891 DOI: 10.1016/J.Celrep.2016.07.074 |
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2016 |
Sok D, Pauthner M, Briney B, Lee JH, Saye-Francisco KL, Hsueh J, Ramos A, Le KM, Jones M, Jardine JG, Bastidas R, Sarkar A, Liang CH, Shivatare SS, Wu CY, ... ... Wilson IA, et al. A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans. Immunity. 45: 31-45. PMID 27438765 DOI: 10.1016/J.Immuni.2016.06.026 |
0.783 |
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2016 |
He L, de Val N, Morris CD, Vora N, Thinnes TC, Kong L, Azadnia P, Sok D, Zhou B, Burton DR, Wilson IA, Nemazee D, Ward AB, Zhu J. Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles. Nature Communications. 7: 12041. PMID 27349934 DOI: 10.1038/Ncomms12041 |
0.35 |
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2016 |
Kong L, He L, de Val N, Vora N, Morris CD, Azadnia P, Sok D, Zhou B, Burton DR, Ward AB, Wilson IA, Zhu J. Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability. Nature Communications. 7: 12040. PMID 27349805 DOI: 10.1038/Ncomms12040 |
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2016 |
MacLeod DT, Choi NM, Briney B, Garces F, Ver LS, Landais E, Murrell B, Wrin T, Kilembe W, Liang CH, Ramos A, Bian CB, Wickramasinghe L, Kong L, Eren K, ... ... Wilson IA, et al. Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch. Immunity. 44: 1215-1226. PMID 27192579 DOI: 10.1016/J.Immuni.2016.04.016 |
0.372 |
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2016 |
Chen W, Dong J, Plate L, Mortenson DE, Brighty GJ, Li S, Liu Y, Galmozzi A, Lee PS, Hulce JJ, Cravatt BF, Saez E, Powers ET, Wilson IA, Sharpless KB, et al. Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding-site Tyr Residue. Journal of the American Chemical Society. PMID 27191344 DOI: 10.1021/Jacs.6B02960 |
0.387 |
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2016 |
Serrano P, Dutta SK, Proudfoot A, Mohanty B, Susac L, Martin B, Geralt M, Jaroszewski L, Godzik A, Elsliger M, Wilson IA, Wüthrich K. NMR in structural genomics to increase structural coverage of the protein universe: Delivered by Prof. Kurt Wüthrich on 7 July 2013 at the 38th FEBS Congress in St. Petersburg, Russia. The Febs Journal. 283: 3870-3881. PMID 27154589 DOI: 10.1111/Febs.13751 |
0.344 |
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2016 |
Chen W, Kong L, Connelly S, Dendle JM, Liu Y, Wilson IA, Powers ET, Kelly JW. Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon. Acs Chemical Biology. PMID 27128252 DOI: 10.1021/Acschembio.5B01035 |
0.4 |
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2016 |
Kong L, Ju B, Chen Y, He L, Ren L, Liu J, Hong K, Su B, Wang Z, Ozorowski G, Ji X, Hua Y, Chen Y, Deller MC, Hao Y, ... ... Wilson IA, et al. Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor. Immunity. PMID 27067056 DOI: 10.1016/J.Immuni.2016.03.006 |
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2016 |
Xu Q, Shoji M, Shibata S, Naito M, Sato K, Elsliger MA, Grant JC, Axelrod HL, Chiu HJ, Farr CL, Jaroszewski L, Knuth MW, Deacon AM, Godzik A, Lesley SA, ... ... Wilson IA, et al. A Distinct Type of Pilus from the Human Microbiome. Cell. PMID 27062925 DOI: 10.1016/J.Cell.2016.03.016 |
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2016 |
Stepanyuk GA, Serrano P, Peralta E, Farr CL, Axelrod HL, Geralt M, Das D, Chiu HJ, Jaroszewski L, Deacon AM, Lesley SA, Elsliger MA, Godzik A, Wilson IA, Wüthrich K, et al. UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex. Acta Crystallographica. Section D, Structural Biology. 72: 497-511. PMID 27050129 DOI: 10.1107/S2059798316001248 |
0.6 |
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2016 |
Jardine JG, Kulp DW, Havenar-Daughton C, Sarkar A, Briney B, Sok D, Sesterhenn F, Ereño-Orbea J, Kalyuzhniy O, Deresa I, Hu X, Spencer S, Jones M, Georgeson E, Adachi Y, ... ... Wilson IA, et al. HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen. Science (New York, N.Y.). 351: 1458-63. PMID 27013733 DOI: 10.1126/Science.Aad9195 |
0.767 |
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2016 |
Behrens AJ, Vasiljevic S, Pritchard LK, Harvey DJ, Andev RS, Krumm SA, Struwe WB, Cupo A, Kumar A, Zitzmann N, Seabright GE, Kramer HB, Spencer DI, Royle L, Lee JH, ... ... Wilson IA, et al. Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein. Cell Reports. PMID 26972002 DOI: 10.1016/J.Celrep.2016.02.058 |
0.405 |
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2016 |
Thornburg NJ, Zhang H, Bangaru S, Sapparapu G, Kose N, Lampley RM, Bombardi RG, Yu Y, Graham S, Branchizio A, Yoder SM, Rock MT, Creech CB, Edwards KM, Lee D, ... ... Wilson IA, et al. H7N9 influenza virus neutralizing antibodies that possess few somatic mutations. The Journal of Clinical Investigation. PMID 26950424 DOI: 10.1172/Jci85317 |
0.378 |
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2016 |
McLuskey K, Grewal JS, Das D, Godzik A, Lesley SA, Deacon AM, Coombs GH, Elsliger MA, Wilson IA, Mottram JC. Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome. The Journal of Biological Chemistry. PMID 26940874 DOI: 10.1074/Jbc.M115.706143 |
0.605 |
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2016 |
Koday MT, Nelson J, Chevalier A, Koday M, Kalinoski H, Stewart L, Carter L, Nieusma T, Lee PS, Ward AB, Wilson IA, Dagley A, Smee DF, Baker D, Fuller DH. A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response. Plos Pathogens. 12: e1005409. PMID 26845438 DOI: 10.1371/Journal.Ppat.1005409 |
0.335 |
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2016 |
Irimia A, Sarkar A, Stanfield RL, Wilson IA. Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10. Immunity. 44: 21-31. PMID 26777395 DOI: 10.1016/J.Immuni.2015.12.001 |
0.756 |
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2016 |
Kong L, Ju B, Ren L, Chen Y, Liu J, He L, Hong K, Su B, Wang Z, Ozorowski G, Ji X, Hua Y, Deller MC, Hao Y, Feng Y, ... ... Wilson IA, et al. Critical determinants in the emergence of broadly neutralizing CD4-binding site antibodies from an HIV-1-infected Chinese donor Immunity. DOI: 10.2210/Pdb5Cd3/Pdb |
0.358 |
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2015 |
de Taeye SW, Ozorowski G, Torrents de la Peña A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, ... ... Wilson IA, et al. Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes. Cell. 163: 1702-15. PMID 26687358 DOI: 10.1016/J.Cell.2015.11.056 |
0.392 |
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2015 |
Garces F, Lee JH, de Val N, Torrents de la Pena A, Kong L, Puchades C, Hua Y, Stanfield RL, Burton DR, Moore JP, Sanders RW, Ward AB, Wilson IA. Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans. Immunity. 43: 1053-63. PMID 26682982 DOI: 10.1016/J.Immuni.2015.11.007 |
0.436 |
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2015 |
Zhu X, Viswanathan K, Raman R, Yu W, Sasisekharan R, Wilson IA. Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants. Cell Reports. PMID 26586437 DOI: 10.1016/J.Celrep.2015.10.027 |
0.364 |
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2015 |
Kong L, Torrents de la Peña A, Deller MC, Garces F, Sliepen K, Hua Y, Stanfield RL, Sanders RW, Wilson IA. Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer. Acta Crystallographica. Section D, Biological Crystallography. 71: 2099-108. PMID 26457433 DOI: 10.1107/S1399004715013917 |
0.453 |
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2015 |
Lee JH, Leaman DP, Kim AS, Torrents de la Peña A, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G, Klein F, Burton DR, Nussenzweig MC, Poignard P, Moore JP, ... ... Wilson IA, et al. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nature Communications. 6: 8167. PMID 26404402 DOI: 10.1038/Ncomms9167 |
0.414 |
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2015 |
Xu Q, Mengin-Lecreulx D, Liu XW, Patin D, Farr CL, Grant JC, Chiu HJ, Jaroszewski L, Knuth MW, Godzik A, Lesley SA, Elsliger MA, Deacon AM, Wilson IA. Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains. Mbio. 6. PMID 26374125 DOI: 10.1128/Mbio.02327-14 |
0.333 |
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2015 |
Julien JP, Lee JH, Ozorowski G, Hua Y, Torrents de la Peña A, de Taeye SW, Nieusma T, Cupo A, Yasmeen A, Golabek M, Pugach P, Klasse PJ, Moore JP, Sanders RW, Ward AB, ... Wilson IA, et al. Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens. Proceedings of the National Academy of Sciences of the United States of America. PMID 26372963 DOI: 10.1073/Pnas.1507793112 |
0.43 |
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2015 |
Ringe RP, Yasmeen A, Ozorowski G, Go EP, Pritchard LK, Guttman M, Ketas TA, Cottrell CA, Wilson IA, Sanders RW, Cupo A, Crispin M, Lee KK, Desaire H, Ward AB, et al. Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers. Journal of Virology. PMID 26311893 DOI: 10.1128/Jvi.01768-15 |
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2015 |
Impagliazzo A, Milder F, Kuipers H, Wagner MV, Zhu X, Hoffman RM, van Meersbergen R, Huizingh J, Wanningen P, Verspuij J, de Man M, Ding Z, Apetri A, Kükrer B, Sneekes-Vriese E, ... ... Wilson IA, et al. A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen. Science (New York, N.Y.). 349: 1301-6. PMID 26303961 DOI: 10.1126/Science.Aac7263 |
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2015 |
Peng Y, Zeng W, Ye H, Han KH, Dharmarajan V, Novick S, Wilson IA, Griffin PR, Friedman JM, Lerner RA. A General Method for Insertion of Functional Proteins within Proteins via Combinatorial Selection of Permissive Junctions. Chemistry & Biology. 22: 1134-43. PMID 26278185 DOI: 10.1016/J.Chembiol.2015.07.011 |
0.308 |
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2015 |
He L, Cheng Y, Kong L, Azadnia P, Giang E, Kim J, Wood MR, Wilson IA, Law M, Zhu J. Approaching rational epitope vaccine design for hepatitis C virus with meta-server and multivalent scaffolding. Scientific Reports. 5: 12501. PMID 26238798 DOI: 10.1038/Srep12501 |
0.367 |
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2015 |
Dutta SK, Serrano P, Geralt M, Axelrod HL, Xu Q, Lesley SA, Godzik A, Deacon AM, Elsliger MA, Wilson IA, Wüthrich K. Cofactor-induced reversible folding of Flavodoxin-4 from Lactobacillus acidophilus. Protein Science : a Publication of the Protein Society. 24: 1600-8. PMID 26177955 DOI: 10.1002/Pro.2743 |
0.359 |
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2015 |
Kong L, Kadam RU, Giang E, Ruwona TB, Nieusma T, Culhane JC, Stanfield RL, Dawson PE, Wilson IA, Law M. Structure of hepatitis C virus envelope glycoprotein E1 antigenic site 314-324 in complex with antibody IGH526. Journal of Molecular Biology. PMID 26135247 DOI: 10.1016/J.Jmb.2015.06.012 |
0.377 |
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2015 |
Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L, Arendt H, Kim HJ, Lee JH, Pugach P, Williams M, ... ... Wilson IA, et al. HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers. Science (New York, N.Y.). 349: aac4223. PMID 26089353 DOI: 10.1126/Science.Aac4223 |
0.399 |
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2015 |
Pritchard LK, Vasiljevic S, Ozorowski G, Seabright GE, Cupo A, Ringe R, Kim HJ, Sanders RW, Doores KJ, Burton DR, Wilson IA, Ward AB, Moore JP, Crispin M. Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers. Cell Reports. 11: 1604-13. PMID 26051934 DOI: 10.1016/J.Celrep.2015.05.017 |
0.448 |
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2015 |
Willis JR, Sapparapu G, Murrell S, Julien JP, Singh V, King HG, Xia Y, Pickens JA, LaBranche CC, Slaughter JC, Montefiori DC, Wilson IA, Meiler J, Crowe JE. Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth. The Journal of Clinical Investigation. 125: 2523-31. PMID 25985274 DOI: 10.1172/Jci80693 |
0.407 |
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2015 |
Lee PS, Zhu X, Yu W, Wilson IA. Design and Structure of an Engineered Disulfide-Stabilized Influenza Virus Hemagglutinin Trimer. Journal of Virology. 89: 7417-20. PMID 25926650 DOI: 10.1128/Jvi.00808-15 |
0.343 |
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2015 |
Deller MC, Johnson HA, Miller MD, Spraggon G, Elsliger MA, Wilson IA, Lesley SA. Crystal structure of a two-subunit TrkA octameric gating ring assembly. Plos One. 10: e0122512. PMID 25826626 DOI: 10.1371/Journal.Pone.0122512 |
0.325 |
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2015 |
Hayashi Y, Caboni L, Das D, Yumoto F, Clayton T, Deller MC, Nguyen P, Farr CL, Chiu HJ, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Tomoda K, ... ... Wilson IA, et al. Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 4666-71. PMID 25825768 DOI: 10.1073/Pnas.1502855112 |
0.567 |
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2015 |
Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien JP, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, et al. Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer. Plos Pathogens. 11: e1004767. PMID 25807248 DOI: 10.1371/Journal.Ppat.1004767 |
0.435 |
|
2015 |
Zhang H, de Vries RP, Tzarum N, Zhu X, Yu W, McBride R, Paulson JC, Wilson IA. A human-infecting H10N8 influenza virus retains a strong preference for avian-type receptors. Cell Host & Microbe. 17: 377-84. PMID 25766296 DOI: 10.1016/J.Chom.2015.02.006 |
0.67 |
|
2015 |
Tzarum N, de Vries RP, Zhu X, Yu W, McBride R, Paulson JC, Wilson IA. Structure and receptor binding of the hemagglutinin from a human H6N1 influenza virus. Cell Host & Microbe. 17: 369-76. PMID 25766295 DOI: 10.1016/J.Chom.2015.02.005 |
0.676 |
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2015 |
Adhikary R, Yu W, Oda M, Walker RC, Chen T, Stanfield RL, Wilson IA, Zimmermann J, Romesberg FE. Adaptive mutations alter antibody structure and dynamics during affinity maturation. Biochemistry. 54: 2085-93. PMID 25756188 DOI: 10.1021/Bi501417Q |
0.358 |
|
2015 |
Lee PS, Arnell AJ, Wilson IA. Structure of the apo anti-influenza CH65 Fab. Acta Crystallographica. Section F, Structural Biology Communications. 71: 145-8. PMID 25664786 DOI: 10.1107/S2053230X14027599 |
0.413 |
|
2015 |
Guttman M, Cupo A, Julien JP, Sanders RW, Wilson IA, Moore JP, Lee KK. Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env. Nature Communications. 6: 6144. PMID 25652336 DOI: 10.1038/Ncomms7144 |
0.446 |
|
2015 |
Ward AB, Wilson IA. Insights into the trimeric HIV-1 envelope glycoprotein structure. Trends in Biochemical Sciences. 40: 101-7. PMID 25600289 DOI: 10.1016/J.Tibs.2014.12.006 |
0.429 |
|
2015 |
Pugach P, Ozorowski G, Cupo A, Ringe R, Yasmeen A, de Val N, Derking R, Kim HJ, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, Julien JP, Burton DR, Wilson IA, et al. A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene. Journal of Virology. 89: 3380-95. PMID 25589637 DOI: 10.1128/Jvi.03473-14 |
0.431 |
|
2015 |
Kong L, Wilson IA, Kwong PD. Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262. Proteins. 83: 590-6. PMID 25546301 DOI: 10.1002/Prot.24747 |
0.401 |
|
2015 |
Stanfield RL, De Castro C, Marzaioli AM, Wilson IA, Pantophlet R. Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose. Glycobiology. 25: 412-9. PMID 25380763 DOI: 10.1093/Glycob/Cwu123 |
0.428 |
|
2015 |
Doores KJ, Kong L, Krumm SA, Le KM, Sok D, Laserson U, Garces F, Poignard P, Wilson IA, Burton DR. Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope. Journal of Virology. 89: 1105-18. PMID 25378488 DOI: 10.1128/Jvi.02905-14 |
0.446 |
|
2015 |
Lee PS, Wilson IA. Structural characterization of viral epitopes recognized by broadly cross-reactive antibodies. Current Topics in Microbiology and Immunology. 386: 323-41. PMID 25037260 DOI: 10.1007/82_2014_413 |
0.424 |
|
2015 |
Jiménez-Dalmaroni MJ, Radcliffe CM, Harvey DJ, Wormald MR, Verdino P, Ainge GD, Larsen DS, Painter GF, Ulevitch R, Beutler B, Rudd PM, Dwek RA, Wilson IA. Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids. Innate Immunity. 21: 175-93. PMID 24591200 DOI: 10.1177/1753425914524077 |
0.328 |
|
2014 |
Stanfield RL, Wilson IA. Antibody Structure. Microbiology Spectrum. 2. PMID 26105818 DOI: 10.1128/microbiolspec.AID-0012-2013 |
0.305 |
|
2014 |
Xu Q, Mengin-Lecreulx D, Patin D, Grant JC, Chiu HJ, Jaroszewski L, Knuth MW, Godzik A, Lesley SA, Elsliger MA, Deacon AM, Wilson IA. Structure-guided functional characterization of DUF1460 reveals a highly specific NlpC/P60 amidase family. Structure (London, England : 1993). 22: 1799-809. PMID 25465128 DOI: 10.1016/J.Str.2014.09.018 |
0.379 |
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2014 |
Sok D, van Gils MJ, Pauthner M, Julien JP, Saye-Francisco KL, Hsueh J, Briney B, Lee JH, Le KM, Lee PS, Hua Y, Seaman MS, Moore JP, Ward AB, Wilson IA, et al. Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex. Proceedings of the National Academy of Sciences of the United States of America. 111: 17624-9. PMID 25422458 DOI: 10.1073/Pnas.1415789111 |
0.404 |
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2014 |
Bird GH, Irimia A, Ofek G, Kwong PD, Wilson IA, Walensky LD. Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies. Nature Structural & Molecular Biology. 21: 1058-67. PMID 25420104 DOI: 10.1038/Nsmb.2922 |
0.417 |
|
2014 |
Bowers PM, Verdino P, Wang Z, da Silva Correia J, Chhoa M, Macondray G, Do M, Neben TY, Horlick RA, Stanfield RL, Wilson IA, King DJ. Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. The Journal of Biological Chemistry. 289: 33557-67. PMID 25320089 DOI: 10.1074/Jbc.M114.607176 |
0.368 |
|
2014 |
Chiu HJ, Grant JC, Farr CL, Jaroszewski L, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA. Structural analysis of arabinose-5-phosphate isomerase from Bacteroides fragilis and functional implications. Acta Crystallographica. Section D, Biological Crystallography. 70: 2640-51. PMID 25286848 DOI: 10.1107/S1399004714017052 |
0.357 |
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2014 |
Garces F, Sok D, Kong L, McBride R, Kim HJ, Saye-Francisco KF, Julien JP, Hua Y, Cupo A, Moore JP, Paulson JC, Ward AB, Burton DR, Wilson IA. Structural evolution of glycan recognition by a family of potent HIV antibodies. Cell. 159: 69-79. PMID 25259921 DOI: 10.1016/J.Cell.2014.09.009 |
0.421 |
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2014 |
Tan GS, Lee PS, Hoffman RM, Mazel-Sanchez B, Krammer F, Leon PE, Ward AB, Wilson IA, Palese P. Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin. Journal of Virology. 88: 13580-92. PMID 25210195 DOI: 10.1128/Jvi.02289-14 |
0.379 |
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2014 |
Xu Q, Deller MC, Nielsen TK, Grant JC, Lesley SA, Elsliger MA, Deacon AM, Wilson IA. Structural insights into the recognition of phosphopeptide by the FHA domain of kanadaptin. Plos One. 9: e107309. PMID 25197798 DOI: 10.1371/Journal.Pone.0107309 |
0.394 |
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2014 |
Kumar A, Punta M, Axelrod HL, Das D, Farr CL, Grant JC, Chiu HJ, Miller MD, Coggill PC, Klock HE, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA. Crystal structures of three representatives of a new Pfam family PF14869 (DUF4488) suggest they function in sugar binding/uptake. Protein Science : a Publication of the Protein Society. 23: 1380-91. PMID 25044324 DOI: 10.1002/Pro.2522 |
0.62 |
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2014 |
Murin CD, Julien JP, Sok D, Stanfield RL, Khayat R, Cupo A, Moore JP, Burton DR, Wilson IA, Ward AB. Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy. Journal of Virology. 88: 10177-88. PMID 24965454 DOI: 10.1128/Jvi.01229-14 |
0.412 |
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2014 |
Guttman M, Garcia NK, Cupo A, Matsui T, Julien JP, Sanders RW, Wilson IA, Moore JP, Lee KK. CD4-induced activation in a soluble HIV-1 Env trimer. Structure (London, England : 1993). 22: 974-84. PMID 24931470 DOI: 10.1016/J.Str.2014.05.001 |
0.33 |
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2014 |
Collins B, Wilson IA. Crystal structure of the C-terminal domain of mouse TLR9. Proteins. 82: 2874-8. PMID 24888966 DOI: 10.1002/Prot.24616 |
0.325 |
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2014 |
Fleischman NM, Das D, Kumar A, Xu Q, Chiu HJ, Jaroszewski L, Knuth MW, Klock HE, Miller MD, Elsliger MA, Godzik A, Lesley SA, Deacon AM, Wilson IA, Toney MD. Molecular characterization of novel pyridoxal-5'-phosphate-dependent enzymes from the human microbiome. Protein Science : a Publication of the Protein Society. 23: 1060-76. PMID 24888348 DOI: 10.1002/Pro.2493 |
0.558 |
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2014 |
Yasmeen A, Ringe R, Derking R, Cupo A, Julien JP, Burton DR, Ward AB, Wilson IA, Sanders RW, Moore JP, Klasse PJ. Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits. Retrovirology. 11: 41. PMID 24884783 DOI: 10.1186/1742-4690-11-41 |
0.413 |
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2014 |
Sok D, Doores KJ, Briney B, Le KM, Saye-Francisco KL, Ramos A, Kulp DW, Julien JP, Menis S, Wickramasinghe L, Seaman MS, Schief WR, Wilson IA, Poignard P, Burton DR. Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV. Science Translational Medicine. 6: 236ra63. PMID 24828077 DOI: 10.1126/Scitranslmed.3008104 |
0.384 |
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2014 |
Blattner C, Lee JH, Sliepen K, Derking R, Falkowska E, de la Peña AT, Cupo A, Julien JP, van Gils M, Lee PS, Peng W, Paulson JC, Poignard P, Burton DR, Moore JP, ... ... Wilson IA, et al. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers. Immunity. 40: 669-80. PMID 24768348 DOI: 10.1016/J.Immuni.2014.04.008 |
0.422 |
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2014 |
Falkowska E, Le KM, Ramos A, Doores KJ, Lee JH, Blattner C, Ramirez A, Derking R, van Gils MJ, Liang CH, Mcbride R, von Bredow B, Shivatare SS, Wu CY, Chan-Hui PY, ... ... Wilson IA, et al. Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers. Immunity. 40: 657-68. PMID 24768347 DOI: 10.1016/J.Immuni.2014.04.009 |
0.407 |
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2014 |
Chung NP, Matthews K, Kim HJ, Ketas TJ, Golabek M, de Los Reyes K, Korzun J, Yasmeen A, Sanders RW, Klasse PJ, Wilson IA, Ward AB, Marozsan AJ, Moore JP, Cupo A. Stable 293Â T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies. Retrovirology. 11: 33. PMID 24767177 DOI: 10.1186/1742-4690-11-33 |
0.359 |
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2014 |
Wyrzucki A, Dreyfus C, Kohler I, Steck M, Wilson IA, Hangartner L. Alternative recognition of the conserved stem epitope in influenza A virus hemagglutinin by a VH3-30-encoded heterosubtypic antibody. Journal of Virology. 88: 7083-92. PMID 24719426 DOI: 10.1128/Jvi.00178-14 |
0.402 |
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2014 |
Lee PS, Ohshima N, Stanfield RL, Yu W, Iba Y, Okuno Y, Kurosawa Y, Wilson IA. Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nature Communications. 5: 3614. PMID 24717798 DOI: 10.1038/Ncomms4614 |
0.395 |
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2014 |
Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJ, van de Winkel JG, Wilson IA, Koster AJ, Taylor RP, Saphire EO, et al. Complement is activated by IgG hexamers assembled at the cell surface. Science (New York, N.Y.). 343: 1260-3. PMID 24626930 DOI: 10.1126/Science.1248943 |
0.603 |
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2014 |
Doria-Rose NA, Schramm CA, Gorman J, Moore PL, Bhiman JN, DeKosky BJ, Ernandes MJ, Georgiev IS, Kim HJ, Pancera M, Staupe RP, Altae-Tran HR, Bailer RT, Crooks ET, Cupo A, ... ... Wilson IA, et al. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature. 509: 55-62. PMID 24590074 DOI: 10.1038/Nature13036 |
0.41 |
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2014 |
Tran K, Poulsen C, Guenaga J, de Val N, de Val Alda N, Wilson R, Sundling C, Li Y, Stanfield RL, Wilson IA, Ward AB, Karlsson Hedestam GB, Wyatt RT. Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proceedings of the National Academy of Sciences of the United States of America. 111: E738-47. PMID 24550318 DOI: 10.1073/Pnas.1319512111 |
0.406 |
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2014 |
Grover RK, Zhu X, Nieusma T, Jones T, Boero I, MacLeod AS, Mark A, Niessen S, Kim HJ, Kong L, Assad-Garcia N, Kwon K, Chesi M, Smider VV, Salomon DR, ... ... Wilson IA, et al. A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union. Science (New York, N.Y.). 343: 656-61. PMID 24503852 DOI: 10.1126/Science.1246135 |
0.402 |
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2014 |
Friesen RH, Lee PS, Stoop EJ, Hoffman RM, Ekiert DC, Bhabha G, Yu W, Juraszek J, Koudstaal W, Jongeneelen M, Korse HJ, Ophorst C, Brinkman-van der Linden EC, Throsby M, Kwakkenbos MJ, ... ... Wilson IA, et al. A common solution to group 2 influenza virus neutralization. Proceedings of the National Academy of Sciences of the United States of America. 111: 445-50. PMID 24335589 DOI: 10.1073/Pnas.1319058110 |
0.38 |
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2014 |
Das D, Chiu HJ, Farr CL, Grant JC, Jaroszewski L, Knuth MW, Miller MD, Tien HJ, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA. Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family. Proteins. 82: 1086-92. PMID 24174223 DOI: 10.1002/Prot.24455 |
0.578 |
|
2014 |
de Vries RP, Zhu X, McBride R, Rigter A, Hanson A, Zhong G, Hatta M, Xu R, Yu W, Kawaoka Y, de Haan CA, Wilson IA, Paulson JC. Hemagglutinin receptor specificity and structural analyses of respiratory droplet-transmissible H5N1 viruses. Journal of Virology. 88: 768-73. PMID 24173215 DOI: 10.1128/Jvi.02690-13 |
0.696 |
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2014 |
Xu Q, Chiu HJ, Farr CL, Jaroszewski L, Knuth MW, Miller MD, Lesley SA, Godzik A, Elsliger MA, Deacon AM, Wilson IA. Structures of a bifunctional cell wall hydrolase CwlT containing a novel bacterial lysozyme and an NlpC/P60 DL-endopeptidase. Journal of Molecular Biology. 426: 169-84. PMID 24051416 DOI: 10.1016/J.Jmb.2013.09.011 |
0.353 |
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2014 |
Xu Q, Grant J, Chiu HJ, Farr CL, Jaroszewski L, Knuth MW, Miller MD, Lesley SA, Godzik A, Elsliger MA, Deacon AM, Wilson IA. Crystal structure of a member of a novel family of dioxygenases (PF10014) reveals a conserved cupin fold and active site. Proteins. 82: 164-70. PMID 23852666 DOI: 10.1002/Prot.24362 |
0.364 |
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2014 |
Wilson I. Broad Neutralization of Viral Pathogens Acta Crystallographica Section a Foundations and Advances. 70: C245-C245. DOI: 10.1107/S205327331409754X |
0.465 |
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2014 |
Stanfield R, Smider V, Wilson I. Bovine antibodies with ultra long H3 Complementarity Determining Regions Acta Crystallographica Section a Foundations and Advances. 70: C255-C255. DOI: 10.1107/S2053273314097447 |
0.36 |
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2014 |
Elsliger M, Deacon A, Godzik A, Lesley S, Hodgson K, Wooley J, Wüthrich K, Wilson I. JCSG – Adapting Structural Genomics to Eukaryotic Complexes Acta Crystallographica Section a Foundations and Advances. 70: C1148-C1148. DOI: 10.1107/S2053273314088512 |
0.321 |
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2014 |
Das D, Yumoto F, Kuchenbecker K, Deacon A, Fletterick R, Wilson I. Understanding disease mutations from the crystal structure of SOX9 with DNA Acta Crystallographica Section a Foundations and Advances. 70: C1398-C1398. DOI: 10.1107/S205327331408601X |
0.572 |
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2014 |
Lee K, Guttman M, Julien J, Cupo A, Sanders R, Wilson I, Moore J. D-102 The potency of broadly neutralizing antibodies directly relates to their ability to recognize the closed pre-fusion form of HIV Env Jaids Journal of Acquired Immune Deficiency Syndromes. 67: 55. DOI: 10.1097/01.Qai.0000456127.20795.54 |
0.359 |
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2013 |
Xu R, de Vries RP, Zhu X, Nycholat CM, McBride R, Yu W, Paulson JC, Wilson IA. Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science (New York, N.Y.). 342: 1230-5. PMID 24311689 DOI: 10.1126/Science.1243761 |
0.667 |
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2013 |
Kong L, Giang E, Nieusma T, Kadam RU, Cogburn KE, Hua Y, Dai X, Stanfield RL, Burton DR, Ward AB, Wilson IA, Law M. Hepatitis C virus E2 envelope glycoprotein core structure. Science (New York, N.Y.). 342: 1090-4. PMID 24288331 DOI: 10.1126/Science.1243876 |
0.342 |
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2013 |
Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, ... ... Wilson IA, et al. The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies. Plos Pathogens. 9: e1003754. PMID 24278016 DOI: 10.1371/Journal.Ppat.1003754 |
0.434 |
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2013 |
Suh EH, Liu Y, Connelly S, Genereux JC, Wilson IA, Kelly JW. Stilbene vinyl sulfonamides as fluorogenic sensors of and traceless covalent kinetic stabilizers of transthyretin that prevent amyloidogenesis. Journal of the American Chemical Society. 135: 17869-80. PMID 24180271 DOI: 10.1021/Ja408230K |
0.322 |
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2013 |
Lyumkis D, Julien JP, de Val N, Cupo A, Potter CS, Klasse PJ, Burton DR, Sanders RW, Moore JP, Carragher B, Wilson IA, Ward AB. Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer. Science (New York, N.Y.). 342: 1484-90. PMID 24179160 DOI: 10.1126/Science.1245627 |
0.436 |
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2013 |
Julien JP, Cupo A, Sok D, Stanfield RL, Lyumkis D, Deller MC, Klasse PJ, Burton DR, Sanders RW, Moore JP, Ward AB, Wilson IA. Crystal structure of a soluble cleaved HIV-1 envelope trimer. Science (New York, N.Y.). 342: 1477-83. PMID 24179159 DOI: 10.1126/Science.1245625 |
0.428 |
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2013 |
Xu R, Palmer SG, Porotto M, Palermo LM, Niewiesk S, Wilson IA, Moscona A. Interaction between the hemagglutinin-neuraminidase and fusion glycoproteins of human parainfluenza virus type III regulates viral growth in vivo. Mbio. 4: e00803-13. PMID 24149514 DOI: 10.1128/Mbio.00803-13 |
0.34 |
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2013 |
Ringe RP, Sanders RW, Yasmeen A, Kim HJ, Lee JH, Cupo A, Korzun J, Derking R, van Montfort T, Julien JP, Wilson IA, Klasse PJ, Ward AB, Moore JP. Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation. Proceedings of the National Academy of Sciences of the United States of America. 110: 18256-61. PMID 24145402 DOI: 10.1073/Pnas.1314351110 |
0.384 |
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2013 |
Tong S, Zhu X, Li Y, Shi M, Zhang J, Bourgeois M, Yang H, Chen X, Recuenco S, Gomez J, Chen LM, Johnson A, Tao Y, Dreyfus C, Yu W, ... ... Wilson IA, et al. New world bats harbor diverse influenza A viruses. Plos Pathogens. 9: e1003657. PMID 24130481 DOI: 10.1371/Journal.Ppat.1003657 |
0.301 |
|
2013 |
Das D, Hervé M, Elsliger MA, Kadam RU, Grant JC, Chiu HJ, Knuth MW, Klock HE, Miller MD, Godzik A, Lesley SA, Deacon AM, Mengin-Lecreulx D, Wilson IA. Structure and function of a novel LD-carboxypeptidase a involved in peptidoglycan recycling. Journal of Bacteriology. 195: 5555-66. PMID 24123814 DOI: 10.1128/Jb.00900-13 |
0.612 |
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2013 |
Bhabha G, Ekiert DC, Jennewein M, Zmasek CM, Tuttle LM, Kroon G, Dyson HJ, Godzik A, Wilson IA, Wright PE. Divergent evolution of protein conformational dynamics in dihydrofolate reductase. Nature Structural & Molecular Biology. 20: 1243-9. PMID 24077226 DOI: 10.1038/Nsmb.2676 |
0.304 |
|
2013 |
Sanders RW, Derking R, Cupo A, Julien JP, Yasmeen A, de Val N, Kim HJ, Blattner C, de la Peña AT, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, van Gils MJ, King CR, ... Wilson IA, et al. A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies. Plos Pathogens. 9: e1003618. PMID 24068931 DOI: 10.1371/Journal.Ppat.1003618 |
0.434 |
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2013 |
Zhu X, Guo YH, Jiang T, Wang YD, Chan KH, Li XF, Yu W, McBride R, Paulson JC, Yuen KY, Qin CF, Che XY, Wilson IA. A unique and conserved neutralization epitope in H5N1 influenza viruses identified by an antibody against the A/Goose/Guangdong/1/96 hemagglutinin. Journal of Virology. 87: 12619-35. PMID 24049169 DOI: 10.1128/Jvi.01577-13 |
0.412 |
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2013 |
Hong M, Lee PS, Hoffman RM, Zhu X, Krause JC, Laursen NS, Yoon SI, Song L, Tussey L, Crowe JE, Ward AB, Wilson IA. Antibody recognition of the pandemic H1N1 Influenza virus hemagglutinin receptor binding site. Journal of Virology. 87: 12471-80. PMID 24027321 DOI: 10.1128/Jvi.01388-13 |
0.411 |
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2013 |
Szent-Gyorgyi C, Stanfield RL, Andreko S, Dempsey A, Ahmed M, Capek S, Waggoner AS, Wilson IA, Bruchez MP. Malachite green mediates homodimerization of antibody VL domains to form a fluorescent ternary complex with singular symmetric interfaces. Journal of Molecular Biology. 425: 4595-613. PMID 23978698 DOI: 10.1016/J.Jmb.2013.08.014 |
0.369 |
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2013 |
Talekar A, DeVito I, Salah Z, Palmer SG, Chattopadhyay A, Rose JK, Xu R, Wilson IA, Moscona A, Porotto M. Identification of a region in the stalk domain of the nipah virus receptor binding protein that is critical for fusion activation. Journal of Virology. 87: 10980-96. PMID 23903846 DOI: 10.1128/Jvi.01646-13 |
0.362 |
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2013 |
Connelly S, DeMartino JK, Boger DL, Wilson IA. Biological and structural evaluation of 10R- and 10S-methylthio-DDACTHF reveals a new role for sulfur in inhibition of glycinamide ribonucleotide transformylase. Biochemistry. 52: 5133-44. PMID 23869564 DOI: 10.1021/Bi4005182 |
0.352 |
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2013 |
Bale S, Julien JP, Bornholdt ZA, Krois AS, Wilson IA, Saphire EO. Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism. Journal of Virology. 87: 10385-8. PMID 23824825 DOI: 10.1128/Jvi.01452-13 |
0.574 |
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2013 |
Klasse PJ, Depetris RS, Pejchal R, Julien JP, Khayat R, Lee JH, Marozsan AJ, Cupo A, Cocco N, Korzun J, Yasmeen A, Ward AB, Wilson IA, Sanders RW, Moore JP. Influences on trimerization and aggregation of soluble, cleaved HIV-1 SOSIP envelope glycoprotein. Journal of Virology. 87: 9873-85. PMID 23824824 DOI: 10.1128/Jvi.01226-13 |
0.405 |
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2013 |
Khayat R, Lee JH, Julien JP, Cupo A, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB. Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers. Journal of Virology. 87: 9865-72. PMID 23824817 DOI: 10.1128/Jvi.01222-13 |
0.43 |
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2013 |
Wang F, Ekiert DC, Ahmad I, Yu W, Zhang Y, Bazirgan O, Torkamani A, Raudsepp T, Mwangi W, Criscitiello MF, Wilson IA, Schultz PG, Smider VV. Reshaping antibody diversity. Cell. 153: 1379-93. PMID 23746848 DOI: 10.1016/J.Cell.2013.04.049 |
0.396 |
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2013 |
Kong L, Lee JH, Doores KJ, Murin CD, Julien JP, McBride R, Liu Y, Marozsan A, Cupo A, Klasse PJ, Hoffenberg S, Caulfield M, King CR, Hua Y, Le KM, ... ... Wilson IA, et al. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nature Structural & Molecular Biology. 20: 796-803. PMID 23708606 DOI: 10.1038/Nsmb.2594 |
0.437 |
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2013 |
Zhang H, Yea K, Xie J, Ruiz D, Wilson IA, Lerner RA. Selecting agonists from single cells infected with combinatorial antibody libraries. Chemistry & Biology. 20: 734-41. PMID 23706638 DOI: 10.1016/J.Chembiol.2013.04.012 |
0.342 |
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2013 |
Julien JP, Sok D, Khayat R, Lee JH, Doores KJ, Walker LM, Ramos A, Diwanji DC, Pejchal R, Cupo A, Katpally U, Depetris RS, Stanfield RL, McBride R, Marozsan AJ, ... ... Wilson IA, et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. Plos Pathogens. 9: e1003342. PMID 23658524 DOI: 10.1371/Journal.Ppat.1003342 |
0.451 |
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2013 |
Laursen NS, Wilson IA. Broadly neutralizing antibodies against influenza viruses. Antiviral Research. 98: 476-83. PMID 23583287 DOI: 10.1016/J.Antiviral.2013.03.021 |
0.353 |
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2013 |
Das D, Lee WS, Grant JC, Chiu HJ, Farr CL, Vance J, Klock HE, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Kornfeld S, Wilson IA. Structure and function of the DUF2233 domain in bacteria and in the human mannose 6-phosphate uncovering enzyme. The Journal of Biological Chemistry. 288: 16789-99. PMID 23572527 DOI: 10.1074/Jbc.M112.434977 |
0.6 |
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2013 |
Dreyfus C, Ekiert DC, Wilson IA. Structure of a classical broadly neutralizing stem antibody in complex with a pandemic H2 influenza virus hemagglutinin. Journal of Virology. 87: 7149-54. PMID 23552413 DOI: 10.1128/Jvi.02975-12 |
0.405 |
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2013 |
Jardine J, Julien JP, Menis S, Ota T, Kalyuzhniy O, McGuire A, Sok D, Huang PS, MacPherson S, Jones M, Nieusma T, Mathison J, Baker D, Ward AB, Burton DR, ... ... Wilson IA, et al. Rational HIV immunogen design to target specific germline B cell receptors. Science (New York, N.Y.). 340: 711-6. PMID 23539181 DOI: 10.1126/Science.1234150 |
0.395 |
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2013 |
Wang F, Sen S, Zhang Y, Ahmad I, Zhu X, Wilson IA, Smider VV, Magliery TJ, Schultz PG. Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation. Proceedings of the National Academy of Sciences of the United States of America. 110: 4261-6. PMID 23440204 DOI: 10.1073/Pnas.1301810110 |
0.379 |
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2013 |
Ward AB, Sali A, Wilson IA. Biochemistry. Integrative structural biology. Science (New York, N.Y.). 339: 913-5. PMID 23430643 DOI: 10.1126/Science.1228565 |
0.301 |
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2013 |
Julien JP, Lee JH, Cupo A, Murin CD, Derking R, Hoffenberg S, Caulfield MJ, King CR, Marozsan AJ, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB. Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9. Proceedings of the National Academy of Sciences of the United States of America. 110: 4351-6. PMID 23426631 DOI: 10.1073/Pnas.1217537110 |
0.459 |
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2013 |
Xu R, Krause JC, McBride R, Paulson JC, Crowe JE, Wilson IA. A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin. Nature Structural & Molecular Biology. 20: 363-70. PMID 23396351 DOI: 10.1038/Nsmb.2500 |
0.415 |
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2013 |
Grimster NP, Connelly S, Baranczak A, Dong J, Krasnova LB, Sharpless KB, Powers ET, Wilson IA, Kelly JW. Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate. Journal of the American Chemical Society. 135: 5656-68. PMID 23350654 DOI: 10.1021/Ja311729D |
0.33 |
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2013 |
Zhu X, Yu W, McBride R, Li Y, Chen LM, Donis RO, Tong S, Paulson JC, Wilson IA. Hemagglutinin homologue from H17N10 bat influenza virus exhibits divergent receptor-binding and pH-dependent fusion activities. Proceedings of the National Academy of Sciences of the United States of America. 110: 1458-63. PMID 23297216 DOI: 10.1073/Pnas.1218509110 |
0.389 |
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2013 |
Lee JY, Kim HS, Baek IW, Back JM, Han MR, Kong SY, Kim JH, Kirchdoerfer RN, Kim JO, Cooper MD, Wilson IA, Kim HJ, Han BW. Overexpression, crystallization and preliminary X-ray crystallographic analysis of the variable lymphocyte receptor 2913 ectodomain fused with internalin B. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 39-41. PMID 23295483 DOI: 10.1107/S1744309112045484 |
0.603 |
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2012 |
Tsibane T, Ekiert DC, Krause JC, Martinez O, Crowe JE, Wilson IA, Basler CF. Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity in H1N1 viruses. Plos Pathogens. 8: e1003067. PMID 23236279 DOI: 10.1371/Journal.Ppat.1003067 |
0.369 |
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2012 |
Moeller A, Kirchdoerfer RN, Potter CS, Carragher B, Wilson IA. Organization of the influenza virus replication machinery. Science (New York, N.Y.). 338: 1631-4. PMID 23180774 DOI: 10.1126/Science.1227270 |
0.32 |
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2012 |
Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath MJ, Nussenzweig MC, Pulendran B, Scanlan CN, Schief WR, Silvestri G, Streeck H, Walker BD, ... ... Wilson IA, et al. A Blueprint for HIV Vaccine Discovery. Cell Host & Microbe. 12: 396-407. PMID 23084910 DOI: 10.1016/J.Chom.2012.09.008 |
0.35 |
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2012 |
Julien JP, Lee PS, Wilson IA. Structural insights into key sites of vulnerability on HIV-1 Env and influenza HA. Immunological Reviews. 250: 180-98. PMID 23046130 DOI: 10.1111/Imr.12005 |
0.433 |
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2012 |
Bale S, Julien JP, Bornholdt ZA, Kimberlin CR, Halfmann P, Zandonatti MA, Kunert J, Kroon GJ, Kawaoka Y, MacRae IJ, Wilson IA, Saphire EO. Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism. Plos Pathogens. 8: e1002916. PMID 23028316 DOI: 10.1371/Journal.Ppat.1002916 |
0.617 |
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2012 |
Lee PS, Yoshida R, Ekiert DC, Sakai N, Suzuki Y, Takada A, Wilson IA. Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity. Proceedings of the National Academy of Sciences of the United States of America. 109: 17040-5. PMID 23027945 DOI: 10.1073/Pnas.1212371109 |
0.41 |
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2012 |
Zhang H, Wilson IA, Lerner RA. Selection of antibodies that regulate phenotype from intracellular combinatorial antibody libraries. Proceedings of the National Academy of Sciences of the United States of America. 109: 15728-33. PMID 23019357 DOI: 10.1073/Pnas.1214275109 |
0.384 |
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2012 |
Zhu X, McBride R, Nycholat CM, Yu W, Paulson JC, Wilson IA. Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. Journal of Virology. 86: 13371-83. PMID 23015718 DOI: 10.1128/Jvi.01426-12 |
0.358 |
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2012 |
Zhu X, Yang H, Guo Z, Yu W, Carney PJ, Li Y, Chen LM, Paulson JC, Donis RO, Tong S, Stevens J, Wilson IA. Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site. Proceedings of the National Academy of Sciences of the United States of America. 109: 18903-8. PMID 23012478 DOI: 10.1073/Pnas.1212579109 |
0.356 |
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2012 |
Kumar A, Möcklinghoff S, Yumoto F, Jaroszewski L, Farr CL, Grzechnik A, Nguyen P, Weichenberger CX, Chiu HJ, Klock HE, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Conklin BR, ... ... Wilson IA, et al. Structure of a novel winged-helix like domain from human NFRKB protein. Plos One. 7: e43761. PMID 22984442 DOI: 10.1371/Journal.Pone.0043761 |
0.36 |
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2012 |
Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, Khayat R, Lee JH, Dillon MA, O'Neil RE, Faynboym AM, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, ... ... Wilson IA, et al. Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature. 489: 526-32. PMID 22982990 DOI: 10.1038/Nature11414 |
0.443 |
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2012 |
Kong L, Giang E, Nieusma T, Robbins JB, Deller MC, Stanfield RL, Wilson IA, Law M. Structure of hepatitis C virus envelope glycoprotein E2 antigenic site 412 to 423 in complex with antibody AP33. Journal of Virology. 86: 13085-8. PMID 22973046 DOI: 10.1128/Jvi.01939-12 |
0.368 |
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2012 |
Buck-Koehntop BA, Stanfield RL, Ekiert DC, Martinez-Yamout MA, Dyson HJ, Wilson IA, Wright PE. Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso. Proceedings of the National Academy of Sciences of the United States of America. 109: 15229-34. PMID 22949637 DOI: 10.1073/Pnas.1213726109 |
0.313 |
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2012 |
Schneemann A, Speir JA, Tan GS, Khayat R, Ekiert DC, Matsuoka Y, Wilson IA. A virus-like particle that elicits cross-reactive antibodies to the conserved stem of influenza virus hemagglutinin. Journal of Virology. 86: 11686-97. PMID 22896619 DOI: 10.1128/Jvi.01694-12 |
0.39 |
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2012 |
Dreyfus C, Laursen NS, Kwaks T, Zuijdgeest D, Khayat R, Ekiert DC, Lee JH, Metlagel Z, Bujny MV, Jongeneelen M, van der Vlugt R, Lamrani M, Korse HJ, Geelen E, Sahin Ö, ... ... Wilson IA, et al. Highly conserved protective epitopes on influenza B viruses. Science (New York, N.Y.). 337: 1343-8. PMID 22878502 DOI: 10.1126/Science.1222908 |
0.358 |
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2012 |
Xu Q, van Wezel GP, Chiu HJ, Jaroszewski L, Klock HE, Knuth MW, Miller MD, Lesley SA, Godzik A, Elsliger MA, Deacon AM, Wilson IA. Structure of an MmyB-like regulator from C. aurantiacus, member of a new transcription factor family linked to antibiotic metabolism in actinomycetes. Plos One. 7: e41359. PMID 22844465 DOI: 10.1371/Journal.Pone.0041359 |
0.307 |
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2012 |
Burton DR, Poignard P, Stanfield RL, Wilson IA. Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses. Science (New York, N.Y.). 337: 183-6. PMID 22798606 DOI: 10.1126/Science.1225416 |
0.414 |
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2012 |
Xu R, Zhu X, McBride R, Nycholat CM, Yu W, Paulson JC, Wilson IA. Functional balance of the hemagglutinin and neuraminidase activities accompanies the emergence of the 2009 H1N1 influenza pandemic. Journal of Virology. 86: 9221-32. PMID 22718832 DOI: 10.1128/Jvi.00697-12 |
0.315 |
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2012 |
Bulawa CE, Connelly S, Devit M, Wang L, Weigel C, Fleming JA, Packman J, Powers ET, Wiseman RL, Foss TR, Wilson IA, Kelly JW, Labaudinière R. Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. Proceedings of the National Academy of Sciences of the United States of America. 109: 9629-34. PMID 22645360 DOI: 10.1073/Pnas.1121005109 |
0.331 |
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2012 |
Depetris RS, Julien JP, Khayat R, Lee JH, Pejchal R, Katpally U, Cocco N, Kachare M, Massi E, David KB, Cupo A, Marozsan AJ, Olson WC, Ward AB, Wilson IA, et al. Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers. The Journal of Biological Chemistry. 287: 24239-54. PMID 22645128 DOI: 10.1074/Jbc.M112.371898 |
0.497 |
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2012 |
Whitehead TA, Chevalier A, Song Y, Dreyfus C, Fleishman SJ, De Mattos C, Myers CA, Kamisetty H, Blair P, Wilson IA, Baker D. Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing. Nature Biotechnology. 30: 543-8. PMID 22634563 DOI: 10.1038/Nbt.2214 |
0.357 |
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2012 |
Kong L, Giang E, Robbins JB, Stanfield RL, Burton DR, Wilson IA, Law M. Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1. Proceedings of the National Academy of Sciences of the United States of America. 109: 9499-504. PMID 22623528 DOI: 10.1073/Pnas.1202924109 |
0.313 |
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2012 |
Nycholat CM, McBride R, Ekiert DC, Xu R, Rangarajan J, Peng W, Razi N, Gilbert M, Wakarchuk W, Wilson IA, Paulson JC. Recognition of sialylated poly-N-acetyllactosamine chains on N- and O-linked glycans by human and avian influenza A virus hemagglutinins. Angewandte Chemie (International Ed. in English). 51: 4860-3. PMID 22505324 DOI: 10.1002/Anie.201200596 |
0.309 |
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2012 |
Ekiert DC, Wilson IA. Broadly neutralizing antibodies against influenza virus and prospects for universal therapies Current Opinion in Virology. 2: 134-141. PMID 22482710 DOI: 10.1016/J.Coviro.2012.02.005 |
0.373 |
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2012 |
Xu Q, Göhler AK, Kosfeld A, Carlton D, Chiu HJ, Klock HE, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Jahreis K, Wilson IA. The structure of Mlc titration factor A (MtfA/YeeI) reveals a prototypical zinc metallopeptidase related to anthrax lethal factor. Journal of Bacteriology. 194: 2987-99. PMID 22467785 DOI: 10.1128/Jb.00038-12 |
0.379 |
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2012 |
Porotto M, Salah Z, DeVito I, Talekar A, Palmer SG, Xu R, Wilson IA, Moscona A. The second receptor binding site of the globular head of the newcastle disease virus hemagglutinin-neuraminidase activates the stalk of multiple paramyxovirus receptor binding proteins to trigger fusion Journal of Virology. 86: 5730-5741. PMID 22438532 DOI: 10.1128/Jvi.06793-11 |
0.344 |
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2012 |
Levisson M, Han GW, Deller MC, Xu Q, Biely P, Hendriks S, Ten Eyck LF, Flensburg C, Roversi P, Miller MD, McMullan D, von Delft F, Kreusch A, Deacon AM, van der Oost J, ... ... Wilson IA, et al. Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima. Proteins. 80: 1545-59. PMID 22411095 DOI: 10.1002/Prot.24041 |
0.343 |
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2012 |
Kirchdoerfer RN, Herrin BR, Han BW, Turnbough CL, Cooper MD, Wilson IA. Variable lymphocyte receptor recognition of the immunodominant glycoprotein of Bacillus anthracis spores. Structure (London, England : 1993). 20: 479-86. PMID 22405006 DOI: 10.1016/J.Str.2012.01.009 |
0.587 |
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2012 |
Hong M, Yoon SI, Wilson IA. Structure and functional characterization of the RNA-binding element of the NLRX1 innate immune modulator. Immunity. 36: 337-47. PMID 22386589 DOI: 10.1016/J.Immuni.2011.12.018 |
0.352 |
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2012 |
Yoon SI, Kurnasov O, Natarajan V, Hong M, Gudkov AV, Osterman AL, Wilson IA. Structural basis of TLR5-flagellin recognition and signaling. Science (New York, N.Y.). 335: 859-64. PMID 22344444 DOI: 10.1126/Science.1215584 |
0.309 |
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2012 |
Fernandes RA, Shore DA, Vuong MT, Yu C, Zhu X, Pereira-Lopes S, Brouwer H, Fennelly JA, Jessup CM, Evans EJ, Wilson IA, Davis SJ. T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements. The Journal of Biological Chemistry. 287: 13324-35. PMID 22262845 DOI: 10.1074/Jbc.M111.332783 |
0.382 |
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2012 |
Xu Q, Christen B, Chiu HJ, Jaroszewski L, Klock HE, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Figurski DH, Shapiro L, Wilson IA. Structure of the pilus assembly protein TadZ from Eubacterium rectale: implications for polar localization. Molecular Microbiology. 83: 712-27. PMID 22211578 DOI: 10.1111/J.1365-2958.2011.07954.X |
0.348 |
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2012 |
Xu R, McBride R, Nycholat CM, Paulson JC, Wilson IA. Structural characterization of the hemagglutinin receptor specificity from the 2009 H1N1 influenza pandemic. Journal of Virology. 86: 982-90. PMID 22072785 DOI: 10.1128/Jvi.06322-11 |
0.392 |
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2012 |
Julien J, Kong L, Pejchal R, Khayat R, Lee J, Stanfield R, Walker L, Doores K, Folkowska E, Poignard P, Depetris R, Sanders R, Koff W, Moore J, Ward A, ... ... Wilson I, et al. Recognition and penetration of the HIV-1 Env glycan shield by potent broadly neutralizing antibodies Retrovirology. 9: P48. DOI: 10.1186/1742-4690-9-S2-P48 |
0.44 |
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2012 |
Castro CD, Clark B, Auyeung K, Marzaioli A, Stanfield R, Wilson I, Pantophlet R. Antigenic mimicry of mammalian oligomannose by a naturally occurring bacterial oligosaccharide and its implications for HIV vaccine design Retrovirology. 9: 337. DOI: 10.1186/1742-4690-9-S2-P337 |
0.395 |
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2012 |
Yu X, Tsibane T, McGraw PA, House FS, Keefer CJ, Hicar MD, Tumpey TM, Pappas C, Perrone LA, Martinez O, Stevens J, Wilson IA, Aguilar PV, Altschuler EL, Basler CF, et al. Erratum: Corrigendum: Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors Nature. 490: 570-570. DOI: 10.1038/Nature11235 |
0.3 |
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2011 |
Soundararajan V, Zheng S, Patel N, Warnock K, Raman R, Wilson IA, Raguram S, Sasisekharan V, Sasisekharan R. Networks link antigenic and receptor-binding sites of influenza hemagglutinin: mechanistic insight into fitter strain propagation. Scientific Reports. 1: 200. PMID 22355715 DOI: 10.1038/Srep00200 |
0.382 |
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2011 |
Walker LM, Sok D, Nishimura Y, Donau O, Sadjadpour R, Gautam R, Shingai M, Pejchal R, Ramos A, Simek MD, Geng Y, Wilson IA, Poignard P, Martin MA, Burton DR. Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque. Proceedings of the National Academy of Sciences of the United States of America. 108: 20125-9. PMID 22123961 DOI: 10.1073/Pnas.1117531108 |
0.357 |
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2011 |
McLellan JS, Pancera M, Carrico C, Gorman J, Julien JP, Khayat R, Louder R, Pejchal R, Sastry M, Dai K, O'Dell S, Patel N, Shahzad-ul-Hussan S, Yang Y, Zhang B, ... ... Wilson IA, et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature. 480: 336-43. PMID 22113616 DOI: 10.1038/Nature10696 |
0.391 |
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2011 |
Stanfield RL, Julien JP, Pejchal R, Gach JS, Zwick MB, Wilson IA. Structure-based design of a protein immunogen that displays an HIV-1 gp41 neutralizing epitope. Journal of Molecular Biology. 414: 460-76. PMID 22033480 DOI: 10.1016/J.Jmb.2011.10.014 |
0.403 |
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2011 |
Pejchal R, Doores KJ, Walker LM, Khayat R, Huang PS, Wang SK, Stanfield RL, Julien JP, Ramos A, Crispin M, Depetris R, Katpally U, Marozsan A, Cupo A, Maloveste S, ... ... Wilson IA, et al. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science (New York, N.Y.). 334: 1097-103. PMID 21998254 DOI: 10.1126/Science.1213256 |
0.457 |
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2011 |
Alhamadsheh MM, Connelly S, Cho A, Reixach N, Powers ET, Pan DW, Wilson IA, Kelly JW, Graef IA. Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity. Science Translational Medicine. 3: 97ra81. PMID 21865539 DOI: 10.1126/Scitranslmed.3002473 |
0.315 |
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2011 |
Walker LM, Huber M, Doores KJ, Falkowska E, Pejchal R, Julien JP, Wang SK, Ramos A, Chan-Hui PY, Moyle M, Mitcham JL, Hammond PW, Olsen OA, Phung P, Fling S, ... ... Wilson IA, et al. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature. 477: 466-70. PMID 21849977 DOI: 10.1038/Nature10373 |
0.405 |
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2011 |
Xu Q, Rawlings ND, Chiu HJ, Jaroszewski L, Klock HE, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA. Structural analysis of papain-like NlpC/P60 superfamily enzymes with a circularly permuted topology reveals potential lipid binding sites. Plos One. 6: e22013. PMID 21799766 DOI: 10.1371/Journal.Pone.0022013 |
0.37 |
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2011 |
Xu Q, Rawlings ND, Farr CL, Chiu HJ, Grant JC, Jaroszewski L, Klock HE, Knuth MW, Miller MD, Weekes D, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA. Structural and sequence analysis of Imelysin-Like proteins implicated in bacterial iron uptake Plos One. 6. PMID 21799754 DOI: 10.1371/Journal.Pone.0021875 |
0.367 |
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2011 |
Ekiert DC, Friesen RH, Bhabha G, Kwaks T, Jongeneelen M, Yu W, Ophorst C, Cox F, Korse HJ, Brandenburg B, Vogels R, Brakenhoff JP, Kompier R, Koldijk MH, Cornelissen LA, ... ... Wilson IA, et al. A highly conserved neutralizing epitope on group 2 influenza A viruses. Science (New York, N.Y.). 333: 843-50. PMID 21737702 DOI: 10.1126/Science.1204839 |
0.374 |
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2011 |
Harris A, Borgnia MJ, Shi D, Bartesaghi A, He H, Pejchal R, Kang Y, Depetris R, Marozsan AJ, Sanders RW, Klasse PJ, Milne JLS, Wilson IA, Olson WC, Moore JP, et al. Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures Proceedings of the National Academy of Sciences of the United States of America. 108: 11440-11445. PMID 21709254 DOI: 10.1073/Pnas.1101414108 |
0.375 |
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2011 |
Hothorn M, Belkhadir Y, Dreux M, Dabi T, Noel JP, Wilson IA, Chory J. Structural basis of steroid hormone perception by the receptor kinase BRI1. Nature. 474: 467-71. PMID 21666665 DOI: 10.1038/Nature10153 |
0.333 |
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2011 |
Verdino P, Witherden DA, Podshivalova K, Rieder SE, Havran WL, Wilson IA. CDNA sequence and Fab crystal structure of HL4E10, a hamster igG lambda light chain antibody stimulatory for γδ T cells Plos One. 6. PMID 21629689 DOI: 10.1371/Journal.Pone.0019828 |
0.399 |
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2011 |
Fleishman SJ, Whitehead TA, Ekiert DC, Dreyfus C, Corn JE, Strauch EM, Wilson IA, Baker D. Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science (New York, N.Y.). 332: 816-21. PMID 21566186 DOI: 10.1126/Science.1202617 |
0.358 |
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2011 |
Han GW, Ko J, Farr CL, Deller MC, Xu Q, Chiu HJ, Miller MD, Sefcikova J, Somarowthu S, Beuning PJ, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA, et al. Crystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity. Proteins. 79: 2146-60. PMID 21538547 DOI: 10.1002/Prot.23035 |
0.322 |
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2011 |
Kirchdoerfer RN, Garner AL, Flack CE, Mee JM, Horswill AR, Janda KD, Kaufmann GF, Wilson IA. Structural basis for ligand recognition and discrimination of a quorum-quenching antibody. The Journal of Biological Chemistry. 286: 17351-8. PMID 21454495 DOI: 10.1074/Jbc.M111.231258 |
0.387 |
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2011 |
Das D, Hervé M, Feuerhelm J, Farr CL, Chiu HJ, Elsliger MA, Knuth MW, Klock HE, Miller MD, Godzik A, Lesley SA, Deacon AM, Mengin-Lecreulx D, Wilson IA. Structure and function of the first full-length murein peptide ligase (Mpl) cell wall recycling protein. Plos One. 6: e17624. PMID 21445265 DOI: 10.1371/Journal.Pone.0017624 |
0.591 |
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2011 |
Xu R, Wilson IA. Structural characterization of an early fusion intermediate of influenza virus hemagglutinin Journal of Virology. 85: 5172-5182. PMID 21367895 DOI: 10.1128/Jvi.02430-10 |
0.372 |
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2011 |
Krause JC, Ekiert DC, Tumpey TM, Smith PB, Wilson IA, Crowe JE. An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody Mbio. 2. PMID 21304166 DOI: 10.1128/Mbio.00345-10 |
0.412 |
|
2011 |
Hwang J, Kim Y, Kang HB, Jaroszewski L, Deacon AM, Lee H, Choi WC, Kim KJ, Kim CH, Kang BS, Lee JO, Oh TK, Kim JW, Wilson IA, Kim MH. Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor. The Journal of Biological Chemistry. 286: 12450-60. PMID 21247902 DOI: 10.1074/Jbc.M110.170803 |
0.374 |
|
2011 |
Verdino P, Witherden DA, Ferguson MS, Corper AL, Schiefner A, Havran WL, Wilson IA. Molecular Insights into γδ T Cell Costimulation by an Anti-JAML Antibody Structure. 19: 80-89. PMID 21220118 DOI: 10.1016/J.Str.2010.10.007 |
0.395 |
|
2011 |
Verdino P, Witherden DA, Ferguson, Corper AL, Schiefner A, Havran WL, Wilson IA. Molecular Insights into gamma delta T Cell Costimulation by an Anti-JAML Antibody Structure. 19: 80-89. DOI: 10.2210/Pdb3Mj9/Pdb |
0.31 |
|
2011 |
Hwang J, Kim Y, Kang HB, Jaroszewski L, Deacon A, Lee H, Choi W, Kim K, Kim C, Kang BS, Lee J, Oh T, Kim JW, Wilson IA, Kim MH. Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor Journal of Biological Chemistry. 286: 12450. DOI: 10.2210/Pdb2Xmq/Pdb |
0.346 |
|
2011 |
Wilson I. The Joint Center for Structural Genomics: exploration of the human gut microbiome Genome Biology. 12: 1-25. DOI: 10.1186/Gb-2011-12-S1-I18 |
0.317 |
|
2011 |
Das D, Hervé M, Mengin-Lecreulx D, Deacon A, Wilson IA. Crystal structures of an enzyme duo involved in bacterial cell wall recycling Acta Crystallographica Section a Foundations of Crystallography. 67: C588-C588. DOI: 10.1107/S0108767311085126 |
0.571 |
|
2010 |
Pejchal R, Wilson IA. Structure-based vaccine design in HIV: blind men and the elephant? Current Pharmaceutical Design. 16: 3744-53. PMID 21128885 DOI: 10.2174/138161210794079173 |
0.42 |
|
2010 |
Garcia KC, Degano M, Stanfield RL, Brunmark A, Jackson MR, Peterson PA, Teyton L, Wilson IA. An αß T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science. 1996. 274: 209-219. Journal of Immunology (Baltimore, Md. : 1950). 185: 6402-12. PMID 21084669 |
0.391 |
|
2010 |
Wang TT, Tan GS, Hai R, Pica N, Ngai L, Ekiert DC, Wilson IA, García-Sastre A, Moran TM, Palese P. Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes. Proceedings of the National Academy of Sciences of the United States of America. 107: 18979-84. PMID 20956293 DOI: 10.1073/Pnas.1013387107 |
0.36 |
|
2010 |
Serrano P, Pedrini B, Geralt M, Jaudzems K, Mohanty B, Horst R, Herrmann T, Elsliger MA, Wilson IA, Wüthrich K. Comparison of NMR and crystal structures highlights conformational isomerism in protein active sites. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1393-405. PMID 20944236 DOI: 10.1107/S1744309110033658 |
0.379 |
|
2010 |
Mohanty B, Serrano P, Pedrini B, Jaudzems K, Geralt M, Horst R, Herrmann T, Elsliger MA, Wilson IA, Wüthrich K. Comparison of NMR and crystal structures for the proteins TM1112 and TM1367. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1381-92. PMID 20944235 DOI: 10.1107/S1744309110020956 |
0.351 |
|
2010 |
Jaudzems K, Geralt M, Serrano P, Mohanty B, Horst R, Pedrini B, Elsliger MA, Wilson IA, Wüthrich K. NMR structure of the protein NP_247299.1: comparison with the crystal structure. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1367-80. PMID 20944234 DOI: 10.1107/S1744309110005890 |
0.349 |
|
2010 |
Xu Q, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Cai X, Carlton D, Chen C, Chiu HJ, Chiu M, Clayton T, Das D, Deller MC, Duan L, Ellrott K, ... ... Wilson IA, et al. Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1354-64. PMID 20944232 DOI: 10.1107/S1744309110021214 |
0.579 |
|
2010 |
Axelrod HL, Kozbial P, McMullan D, Krishna SS, Miller MD, Abdubek P, Acosta C, Astakhova T, Carlton D, Caruthers J, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, ... ... Wilson IA, et al. Conformational changes associated with the binding of zinc acetate at the putative active site of XcTcmJ, a cupin from Xanthomonas campestris pv. campestris. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1347-53. PMID 20944231 DOI: 10.1107/S1744309109021988 |
0.376 |
|
2010 |
Axelrod HL, Das D, Abdubek P, Astakhova T, Bakolitsa C, Carlton D, Chen C, Chiu HJ, Clayton T, Deller MC, Duan L, Ellrott K, Farr CL, Feuerhelm J, Grant JC, ... ... Wilson IA, et al. Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved α+β core domain and an auxiliary C-terminal treble-clef zinc finger. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1335-46. PMID 20944230 DOI: 10.1107/S1744309110020166 |
0.595 |
|
2010 |
Chiu HJ, Abdubek P, Astakhova T, Axelrod HL, Carlton D, Clayton T, Das D, Deller MC, Duan L, Feuerhelm J, Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, ... ... Wilson IA, et al. The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1317-25. PMID 20944228 DOI: 10.1107/S1744309110021688 |
0.628 |
|
2010 |
Kumar A, Chiu HJ, Axelrod HL, Morse A, Elsliger MA, Wilson IA, Deacon A. Ligands in PSI structures. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1309-16. PMID 20944227 DOI: 10.1107/S1744309110008092 |
0.332 |
|
2010 |
Xu Q, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Cai X, Carlton D, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Ellrott K, Farr CL, ... ... Wilson IA, et al. Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1297-305. PMID 20944225 DOI: 10.1107/S1744309110023055 |
0.577 |
|
2010 |
Yeh AP, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Cai X, Carlton D, Chen C, Chiu HJ, Chiu M, Clayton T, Das D, Deller MC, Duan L, Ellrott K, ... ... Wilson IA, et al. Structure of Bacteroides thetaiotaomicron BT2081 at 2.05 Å resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1287-96. PMID 20944224 DOI: 10.1107/S1744309110028228 |
0.615 |
|
2010 |
Xu Q, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Cai X, Carlton D, Chen C, Chiu HJ, Chiu M, Clayton T, Das D, Deller MC, Duan L, Ellrott K, ... ... Wilson IA, et al. A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolution. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1281-6. PMID 20944223 DOI: 10.1107/S1744309110006548 |
0.584 |
|
2010 |
Bakolitsa C, Xu Q, Rife CL, Abdubek P, Astakhova T, Axelrod HL, Carlton D, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Ellrott K, Farr CL, ... ... Wilson IA, et al. Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1274-80. PMID 20944222 DOI: 10.1107/S1744309110032999 |
0.623 |
|
2010 |
Das D, Finn RD, Carlton D, Miller MD, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Chen C, Chiu HJ, Chiu M, Clayton T, Deller MC, Duan L, Ellrott K, ... ... Wilson IA, et al. The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1265-73. PMID 20944221 DOI: 10.1107/S1744309109046788 |
0.572 |
|
2010 |
Das D, Kozbial P, Han GW, Carlton D, Jaroszewski L, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Chen C, Chiu HJ, Chiu M, Clayton T, Deller MC, Duan L, ... ... Wilson IA, et al. The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1254-60. PMID 20944219 DOI: 10.1107/S1744309109018168 |
0.6 |
|
2010 |
Kumar A, Lomize A, Jin KK, Carlton D, Miller MD, Jaroszewski L, Abdubek P, Astakhova T, Axelrod HL, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Feuerhelm J, ... ... Wilson IA, et al. Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1245-53. PMID 20944218 DOI: 10.1107/S1744309109042481 |
0.597 |
|
2010 |
Han GW, Elsliger MA, Yeates TO, Xu Q, Murzin AG, Krishna SS, Jaroszewski L, Abdubek P, Astakhova T, Axelrod HL, Carlton D, Chen C, Chiu HJ, Clayton T, Das D, ... ... Wilson IA, et al. Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1237-44. PMID 20944217 DOI: 10.1107/S1744309110025534 |
0.625 |
|
2010 |
Xu Q, McMullan D, Jaroszewski L, Krishna SS, Elsliger MA, Yeh AP, Abdubek P, Astakhova T, Axelrod HL, Carlton D, Chiu HJ, Clayton T, Duan L, Feuerhelm J, Grant J, ... ... Wilson IA, et al. Structure of an essential bacterial protein YeaZ (TM0874) from Thermotoga maritima at 2.5 Å resolution. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1230-6. PMID 20944216 DOI: 10.1107/S1744309109022192 |
0.358 |
|
2010 |
Han GW, Bakolitsa C, Miller MD, Kumar A, Carlton D, Najmanovich RJ, Abdubek P, Astakhova T, Axelrod HL, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, ... ... Wilson IA, et al. Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1218-25. PMID 20944214 DOI: 10.1107/S1744309109050416 |
0.607 |
|
2010 |
Bakolitsa C, Kumar A, McMullan D, Krishna SS, Miller MD, Carlton D, Najmanovich R, Abdubek P, Astakhova T, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Feuerhelm J, ... ... Wilson IA, et al. The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1211-7. PMID 20944213 DOI: 10.1107/S1744309109022684 |
0.35 |
|
2010 |
Bakolitsa C, Bateman A, Jin KK, McMullan D, Krishna SS, Miller MD, Abdubek P, Acosta C, Astakhova T, Axelrod HL, Burra P, Carlton D, Chiu HJ, Clayton T, Das D, ... ... Wilson IA, et al. The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45 Å resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1198-204. PMID 20944211 DOI: 10.1107/S1744309109025196 |
0.58 |
|
2010 |
Bakolitsa C, Kumar A, Jin KK, McMullan D, Krishna SS, Miller MD, Abdubek P, Acosta C, Astakhova T, Axelrod HL, Burra P, Carlton D, Chen C, Chiu HJ, Clayton T, ... ... Wilson IA, et al. Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1182-9. PMID 20944209 DOI: 10.1107/S1744309109050647 |
0.597 |
|
2010 |
Das D, Grishin NV, Kumar A, Carlton D, Bakolitsa C, Miller MD, Abdubek P, Astakhova T, Axelrod HL, Burra P, Chen C, Chiu HJ, Chiu M, Clayton T, Deller MC, ... ... Wilson IA, et al. The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1174-81. PMID 20944208 DOI: 10.1107/S1744309109022672 |
0.58 |
|
2010 |
Miller MD, Aravind L, Bakolitsa C, Rife CL, Carlton D, Abdubek P, Astakhova T, Axelrod HL, Chiu HJ, Clayton T, Deller MC, Duan L, Feuerhelm J, Grant JC, Han GW, ... ... Wilson IA, et al. Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1167-73. PMID 20944207 DOI: 10.1107/S1744309110007517 |
0.381 |
|
2010 |
Krishna SS, Aravind L, Bakolitsa C, Caruthers J, Carlton D, Miller MD, Abdubek P, Astakhova T, Axelrod HL, Chiu HJ, Clayton T, Deller MC, Duan L, Feuerhelm J, Grant JC, ... ... Wilson IA, et al. The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1160-6. PMID 20944206 DOI: 10.1107/S1744309110002514 |
0.357 |
|
2010 |
Chiu HJ, Bakolitsa C, Skerra A, Lomize A, Carlton D, Miller MD, Krishna SS, Abdubek P, Astakhova T, Axelrod HL, Clayton T, Deller MC, Duan L, Feuerhelm J, Grant JC, ... ... Wilson IA, et al. Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1153-9. PMID 20944205 DOI: 10.1107/S1744309109037749 |
0.319 |
|
2010 |
Krishna SS, Weekes D, Bakolitsa C, Elsliger MA, Wilson IA, Godzik A, Wooley J. TOPSAN: use of a collaborative environment for annotating, analyzing and disseminating data on JCSG and PSI structures. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1143-7. PMID 20944203 DOI: 10.1107/S1744309110035736 |
0.325 |
|
2010 |
Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wooley J, Wüthrich K, Wilson IA. The JCSG high-throughput structural biology pipeline. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1137-42. PMID 20944202 DOI: 10.1107/S1744309110038212 |
0.322 |
|
2010 |
Xu Q, Eguchi T, Mathews II, Rife CL, Chiu HJ, Farr CL, Feuerhelm J, Jaroszewski L, Klock HE, Knuth MW, Miller MD, Weekes D, Elsliger MA, Deacon AM, Godzik A, ... ... Wilson IA, et al. Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids. Journal of Molecular Biology. 404: 403-17. PMID 20869368 DOI: 10.1016/J.Jmb.2010.09.032 |
0.356 |
|
2010 |
Doores KJ, Fulton Z, Hong V, Patel MK, Scanlan CN, Wormald MR, Finn MG, Burton DR, Wilson IA, Davis BG. A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity. Proceedings of the National Academy of Sciences of the United States of America. 107: 17107-12. PMID 20852065 DOI: 10.1073/Pnas.1002717107 |
0.421 |
|
2010 |
Das D, Finn RD, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Cai X, Carlton D, Chen C, Chiu HJ, Chiu M, Clayton T, Deller MC, Duan L, Ellrott K, ... ... Wilson IA, et al. The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu. Protein Science : a Publication of the Protein Society. 19: 2131-40. PMID 20836087 DOI: 10.1002/Pro.497 |
0.592 |
|
2010 |
Verdino P, Witherden DA, Havran WL, Wilson IA. The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K. Science (New York, N.Y.). 329: 1210-4. PMID 20813955 DOI: 10.1126/Science.1187996 |
0.321 |
|
2010 |
Huber M, Le KM, Doores KJ, Fulton Z, Stanfield RL, Wilson IA, Burton DR. Very few substitutions in a germ line antibody are required to initiate significant domain exchange. Journal of Virology. 84: 10700-7. PMID 20702640 DOI: 10.1128/Jvi.01111-10 |
0.345 |
|
2010 |
Doores KJ, Fulton Z, Huber M, Wilson IA, Burton DR. Antibody 2G12 recognizes di-mannose equivalently in domain- and nondomain-exchanged forms but only binds the HIV-1 glycan shield if domain exchanged. Journal of Virology. 84: 10690-9. PMID 20702629 DOI: 10.1128/Jvi.01110-10 |
0.405 |
|
2010 |
Pejchal R, Walker LM, Stanfield RL, Phogat SK, Koff WC, Poignard P, Burton DR, Wilson IA. Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1. Proceedings of the National Academy of Sciences of the United States of America. 107: 11483-8. PMID 20534513 DOI: 10.1073/Pnas.1004600107 |
0.467 |
|
2010 |
Dermoun Z, Foulon A, Miller MD, Harrington DJ, Deacon AM, Sebban-Kreuzer C, Roche P, Lafitte D, Bornet O, Wilson IA, Dolla A. TM0486 from the hyperthermophilic anaerobe Thermotoga maritima is a thiamin-binding protein involved in response of the cell to oxidative conditions. Journal of Molecular Biology. 400: 463-76. PMID 20471400 DOI: 10.1016/J.Jmb.2010.05.014 |
0.33 |
|
2010 |
Yoshida K, Corper AL, Herro R, Jabri B, Wilson IA, Teyton L. The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity. The Journal of Clinical Investigation. 120: 1578-90. PMID 20407212 DOI: 10.1172/Jci41502 |
0.322 |
|
2010 |
Matsumoto Y, Xu Q, Miyazaki S, Kaito C, Farr CL, Axelrod HL, Chiu HJ, Klock HE, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Sekimizu K, ... Wilson IA, et al. Structure of a virulence regulatory factor CvfB reveals a novel winged helix RNA binding module. Structure (London, England : 1993). 18: 537-47. PMID 20399190 DOI: 10.1016/J.Str.2010.02.007 |
0.317 |
|
2010 |
Xu R, Ekiert DC, Krause JC, Hai R, Crowe JE, Wilson IA. Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus. Science (New York, N.Y.). 328: 357-60. PMID 20339031 DOI: 10.1126/Science.1186430 |
0.365 |
|
2010 |
Connelly S, Choi S, Johnson SM, Kelly JW, Wilson IA. Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses. Current Opinion in Structural Biology. 20: 54-62. PMID 20133122 DOI: 10.1016/J.Sbi.2009.12.009 |
0.326 |
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2010 |
Das D, Moiani D, Axelrod HL, Miller MD, McMullan D, Jin KK, Abdubek P, Astakhova T, Burra P, Carlton D, Chiu HJ, Clayton T, Deller MC, Duan L, Ernst D, ... ... Wilson IA, et al. Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair. Journal of Molecular Biology. 397: 647-63. PMID 20122942 DOI: 10.1016/J.Jmb.2010.01.049 |
0.568 |
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2010 |
Choi S, Connelly S, Reixach N, Wilson IA, Kelly JW. Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma. Nature Chemical Biology. 6: 133-9. PMID 20081815 DOI: 10.1038/Nchembio.281 |
0.344 |
|
2010 |
Scheeff ED, Axelrod HL, Miller MD, Chiu HJ, Deacon AM, Wilson IA, Manning G. Genomics, evolution, and crystal structure of a new family of bacterial spore kinases. Proteins. 78: 1470-82. PMID 20077512 DOI: 10.1002/Prot.22663 |
0.346 |
|
2010 |
Choi S, Reixach N, Connelly S, Johnson SM, Wilson IA, Kelly JW. A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity. Journal of the American Chemical Society. 132: 1359-70. PMID 20043671 DOI: 10.1021/Ja908562Q |
0.33 |
|
2010 |
Xu R, McBride R, Paulson JC, Basler CF, Wilson IA. Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic. Journal of Virology. 84: 1715-21. PMID 20007271 DOI: 10.1128/Jvi.02162-09 |
0.42 |
|
2010 |
Xu Q, Bateman A, Finn RD, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Carlton D, Chen C, Chiu HJ, Chiu M, Clayton T, Das D, Deller MC, Duan L, ... ... Wilson IA, et al. Bacterial pleckstrin homology domains: a prokaryotic origin for the PH domain. Journal of Molecular Biology. 396: 31-46. PMID 19913036 DOI: 10.1016/J.Jmb.2009.11.006 |
0.57 |
|
2010 |
Schiefner A, Wilson IA. Presentation of lipid antigens by CD1 glycoproteins. Current Pharmaceutical Design. 15: 3311-7. PMID 19860680 DOI: 10.2174/138161209789105108 |
0.363 |
|
2010 |
Garcia KC, Degano M, Stanfield RL, Brunmark A, Jackson MR, Peterson PA, Teyton L, Wilson IA. An αβ T cell receptor structure at 2.5 Å and its orientation in the TCR-MHC complex Journal of Immunology. 185: 209-219. DOI: 10.1126/science.274.5285.209 |
0.406 |
|
2009 |
Zhu X, Tanaka F, Lerner RA, Barbas CF, Wilson IA. Direct observation of an enamine intermediate in amine catalysis. Journal of the American Chemical Society. 131: 18206-7. PMID 19968282 DOI: 10.1021/Ja907271A |
0.383 |
|
2009 |
Landais E, Romagnoli PA, Corper AL, Shires J, Altman JD, Wilson IA, Garcia KC, Teyton L. New design of MHC class II tetramers to accommodate fundamental principles of antigen presentation. Journal of Immunology (Baltimore, Md. : 1950). 183: 7949-57. PMID 19923463 DOI: 10.4049/Jimmunol.0902493 |
0.488 |
|
2009 |
Debler EW, Müller R, Hilvert D, Wilson IA. An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket. Proceedings of the National Academy of Sciences of the United States of America. 106: 18539-44. PMID 19846764 DOI: 10.1073/Pnas.0902700106 |
0.715 |
|
2009 |
Schiefner A, Fujio M, Wu D, Wong CH, Wilson IA. Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. Journal of Molecular Biology. 394: 71-82. PMID 19732779 DOI: 10.1016/J.Jmb.2009.08.061 |
0.318 |
|
2009 |
Xu Q, Traag BA, Willemse J, McMullan D, Miller MD, Elsliger MA, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Carlton D, Chen C, Chiu HJ, Chruszcz M, Clayton T, ... ... Wilson IA, et al. Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes. The Journal of Biological Chemistry. 284: 25268-79. PMID 19567872 DOI: 10.1074/Jbc.M109.018564 |
0.616 |
|
2009 |
Pejchal R, Gach JS, Brunel FM, Cardoso RM, Stanfield RL, Dawson PE, Burton DR, Zwick MB, Wilson IA. A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies. Journal of Virology. 83: 8451-62. PMID 19515770 DOI: 10.1128/Jvi.00685-09 |
0.452 |
|
2009 |
Xu Q, Carlton D, Miller MD, Elsliger MA, Krishna SS, Abdubek P, Astakhova T, Burra P, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Feuerhelm J, Grant JC, ... ... Wilson IA, et al. Crystal structure of histidine phosphotransfer protein ShpA, an essential regulator of stalk biogenesis in Caulobacter crescentus. Journal of Molecular Biology. 390: 686-98. PMID 19450606 DOI: 10.1016/J.Jmb.2009.05.023 |
0.34 |
|
2009 |
Kwong PD, Wilson IA. HIV-1 and influenza antibodies: Seeing antigens in new ways Nature Immunology. 10: 573-578. PMID 19448659 DOI: 10.1038/Ni.1746 |
0.38 |
|
2009 |
An Y, Chen CY, Moyer B, Rotkiewicz P, Elsliger MA, Godzik A, Wilson IA, Balch WE. Structural and functional analysis of the globular head domain of p115 provides insight into membrane tethering. Journal of Molecular Biology. 391: 26-41. PMID 19414022 DOI: 10.1016/J.Jmb.2009.04.062 |
0.33 |
|
2009 |
Zheng M, Cooper DR, Grossoehme NE, Yu M, Hung LW, Cieslik M, Derewenda U, Lesley SA, Wilson IA, Giedroc DP, Derewenda ZS. Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains. Acta Crystallographica. Section D, Biological Crystallography. 65: 356-65. PMID 19307717 DOI: 10.1107/S0907444909004727 |
0.35 |
|
2009 |
Ekiert DC, Bhabha G, Elsliger MA, Friesen RH, Jongeneelen M, Throsby M, Goudsmit J, Wilson IA. Antibody recognition of a highly conserved influenza virus epitope. Science (New York, N.Y.). 324: 246-51. PMID 19251591 DOI: 10.1126/Science.1171491 |
0.383 |
|
2009 |
Xu Q, Sudek S, McMullan D, Miller MD, Geierstanger B, Jones DH, Krishna SS, Spraggon G, Bursalay B, Abdubek P, Acosta C, Ambing E, Astakhova T, Axelrod HL, Carlton D, ... ... Wilson IA, et al. Structural basis of murein peptide specificity of a gamma-D-glutamyl-l-diamino acid endopeptidase. Structure (London, England : 1993). 17: 303-13. PMID 19217401 DOI: 10.1016/J.Str.2008.12.008 |
0.344 |
|
2009 |
Schwede T, Sali A, Honig B, Levitt M, Berman HM, Jones D, Brenner SE, Burley SK, Das R, Dokholyan NV, Dunbrack RL, Fidelis K, Fiser A, Godzik A, Huang YJ, ... ... Wilson IA, et al. Outcome of a workshop on applications of protein models in biomedical research. Structure (London, England : 1993). 17: 151-9. PMID 19217386 DOI: 10.1016/J.Str.2008.12.014 |
0.454 |
|
2009 |
Das D, Kozbial P, Axelrod HL, Miller MD, McMullan D, Krishna SS, Abdubek P, Acosta C, Astakhova T, Burra P, Carlton D, Chen C, Chiu HJ, Clayton T, Deller MC, ... ... Wilson IA, et al. Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 A resolution. Proteins. 75: 296-307. PMID 19173316 DOI: 10.1002/Prot.22360 |
0.602 |
|
2009 |
Das D, Krishna SS, McMullan D, Miller MD, Xu Q, Abdubek P, Acosta C, Astakhova T, Axelrod HL, Burra P, Carlton D, Chiu HJ, Clayton T, Deller MC, Duan L, ... ... Wilson IA, et al. Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution. Proteins. 75: 264-71. PMID 19127588 DOI: 10.1002/Prot.22338 |
0.594 |
|
2009 |
Xu Q, Rife CL, Carlton D, Miller MD, Krishna SS, Elsliger MA, Abdubek P, Astakhova T, Chiu HJ, Clayton T, Duan L, Feuerhelm J, Grzechnik SK, Hale J, Han GW, ... ... Wilson IA, et al. Crystal structure of a novel archaeal AAA+ ATPase SSO1545 from Sulfolobus solfataricus. Proteins. 74: 1041-9. PMID 19089981 DOI: 10.1002/Prot.22325 |
0.368 |
|
2009 |
Xu Q, McMullan D, Abdubek P, Astakhova T, Carlton D, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Elsliger MA, Feuerhelm J, Hale J, Han GW, ... ... Wilson IA, et al. A structural basis for the regulatory inactivation of DnaA. Journal of Molecular Biology. 385: 368-80. PMID 19000695 DOI: 10.1016/J.Jmb.2008.10.059 |
0.614 |
|
2009 |
Fulton Z, Doores KJ, Scanlan CN, Wormald MR, Dwek RA, Wilson IA, Davis BG. P19-03. Molecular mechanisms for enhancing the antigenicity of the carbohydrate epitope of the broadly neutralizing anti-HIV-1 antibody 2G12 Retrovirology. 6: P323. DOI: 10.1186/1742-4690-6-S3-P323 |
0.314 |
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2009 |
Doores KJ, Fulton Z, Scanlan CN, Wormald MR, Dwek RA, Wilson IA, Burton DR, Davis BG. P12-06. A 'non-self' mimic of the natural epitope of anti-HIV antibody 2G12 shows enhanced antigenicity Retrovirology. 6: P172. DOI: 10.1186/1742-4690-6-S3-P172 |
0.35 |
|
2008 |
Zajonc DM, Striegl H, Dascher CC, Wilson IA. The crystal structure of avian CD1 reveals a smaller, more primordial antigen-binding pocket compared to mammalian CD1 Proceedings of the National Academy of Sciences of the United States of America. 105: 17925-17930. PMID 19004781 DOI: 10.1073/Pnas.0809814105 |
0.365 |
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2008 |
Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure (London, England : 1993). 16: 1659-67. PMID 19000818 DOI: 10.1016/J.Str.2008.08.018 |
0.317 |
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2008 |
Shore DA, Issafras H, Landais E, Teyton L, Wilson IA. The Crystal Structure of CD8 in Complex with YTS156.7.7 Fab and Interaction with Other CD8 Antibodies Define the Binding Mode of CD8 αβ to MHC Class I Journal of Molecular Biology. 384: 1190-1202. PMID 18929574 DOI: 10.1016/J.Jmb.2008.09.069 |
0.4 |
|
2008 |
Han BW, Herrin BR, Cooper MD, Wilson IA. Antigen recognition by variable lymphocyte receptors. Science (New York, N.Y.). 321: 1834-7. PMID 18818359 DOI: 10.1126/Science.1162484 |
0.605 |
|
2008 |
Yu X, Tsibane T, McGraw PA, House FS, Keefer CJ, Hicar MD, Tumpey TM, Pappas C, Perrone LA, Martinez O, Stevens J, Wilson IA, Aguilar PV, Altschuler EL, Basler CF, et al. Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. Nature. 455: 532-6. PMID 18716625 DOI: 10.1038/Nature07231 |
0.374 |
|
2008 |
Xu X, Zhu X, Dwek RA, Stevens J, Wilson IA. Structural characterization of the 1918 influenza virus H1N1 neuraminidase. Journal of Virology. 82: 10493-501. PMID 18715929 DOI: 10.1128/Jvi.00959-08 |
0.34 |
|
2008 |
Verdino P, Aldag C, Hilvert D, Wilson IA. Closely related antibody receptors exploit fundamentally different strategies for steroid recognition Proceedings of the National Academy of Sciences of the United States of America. 105: 11725-11730. PMID 18689687 DOI: 10.1073/Pnas.0801783105 |
0.405 |
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2008 |
Stevens J, Blixt O, Chen LM, Donis RO, Paulson JC, Wilson IA. Recent Avian H5N1 Viruses Exhibit Increased Propensity for Acquiring Human Receptor Specificity Journal of Molecular Biology. 381: 1382-1394. PMID 18672252 DOI: 10.1016/J.Jmb.2008.04.016 |
0.332 |
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2008 |
Zhu X, Xu X, Wilson IA. Structure determination of the 1918 H1N1 neuraminidase from a crystal with lattice-translocation defects Acta Crystallographica Section D: Biological Crystallography. 64: 843-850. PMID 18645233 DOI: 10.1107/S0907444908016648 |
0.349 |
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2008 |
Dhillon AK, Stanfield RL, Gorny MK, Williams C, Zolla-Pazner S, Wilson IA. Structure determination of an anti-HIV-1 Fab 447-52D-peptide complex from an epitaxially twinned data set Acta Crystallographica Section D: Biological Crystallography. 64: 792-802. PMID 18566514 DOI: 10.1107/S0907444908013978 |
0.43 |
|
2008 |
Astronomo RD, Lee HK, Scanlan CN, Pantophlet R, Huang CY, Wilson IA, Blixt O, Dwek RA, Wong CH, Burton DR. A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120. Journal of Virology. 82: 6359-68. PMID 18434393 DOI: 10.1128/Jvi.00293-08 |
0.424 |
|
2008 |
Wei CJ, Xu L, Kong WP, Shi W, Canis K, Stevens J, Yang ZY, Dell A, Haslam SM, Wilson IA, Nabel GJ. Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus. Journal of Virology. 82: 6200-8. PMID 18417563 DOI: 10.1128/Jvi.00187-08 |
0.385 |
|
2008 |
Debler EW, Müller R, Hilvert D, Wilson IA. Conformational isomerism can limit antibody catalysis. The Journal of Biological Chemistry. 283: 16554-60. PMID 18417480 DOI: 10.1074/Jbc.M710256200 |
0.74 |
|
2008 |
Kozbial P, Xu Q, Chiu HJ, McMullan D, Krishna SS, Miller MD, Abdubek P, Acosta C, Astakhova T, Axelrod HL, Carlton D, Clayton T, Deller M, Duan L, Elias Y, ... ... Wilson IA, et al. Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold. Proteins. 71: 1589-96. PMID 18324683 DOI: 10.1002/Prot.22020 |
0.331 |
|
2008 |
Debler EW, Kaufmann GF, Meijler MM, Heine A, Mee JM, Pljevaljcic G, Di Bilio AJ, Schultz PG, Millar DP, Janda KD, Wilson IA, Gray HB, Lerner RA. Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex. Science (New York, N.Y.). 319: 1232-5. PMID 18309081 DOI: 10.1126/Science.1153445 |
0.709 |
|
2008 |
Zajonc DM, Savage PB, Bendelac A, Wilson IA, Teyton L. Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Vα14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids Journal of Molecular Biology. 377: 1104-1116. PMID 18295796 DOI: 10.1016/J.Jmb.2008.01.061 |
0.342 |
|
2008 |
Xu Q, Kozbial P, McMullan D, Krishna SS, Brittain SM, Ficarro SB, DiDonato M, Miller MD, Abdubek P, Axelrod HL, Chiu HJ, Clayton T, Duan L, Elsliger MA, Feuerhelm J, ... ... Wilson IA, et al. Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 A resolution. Proteins. 71: 1546-52. PMID 18275082 DOI: 10.1002/Prot.21992 |
0.349 |
|
2008 |
Axelrod HL, McMullan D, Krishna SS, Miller MD, Elsliger MA, Abdubek P, Ambing E, Astakhova T, Carlton D, Chiu HJ, Clayton T, Duan L, Feuerhelm J, Grzechnik SK, Hale J, ... ... Wilson IA, et al. Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 A resolution. Proteins. 71: 1042-9. PMID 18260100 DOI: 10.1002/Prot.21967 |
0.331 |
|
2008 |
Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, ... ... Wilson IA, et al. Protein production and purification. Nature Methods. 5: 135-46. PMID 18235434 DOI: 10.1038/Nmeth.F.202 |
0.466 |
|
2008 |
Menendez A, Calarese DA, Stanfield RL, Chow KC, Scanlan CN, Kunert R, Katinger H, Burton DR, Wilson IA, Scott JK. A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1380-92. PMID 18198210 DOI: 10.1096/Fj.07-8983Com |
0.806 |
|
2008 |
Burley SK, Joachimiak A, Montelione GT, Wilson IA. Contributions to the NIH-NIGMS Protein Structure Initiative from the PSI Production Centers Structure. 16: 5-11. PMID 18184575 DOI: 10.1016/J.Str.2007.12.002 |
0.511 |
|
2008 |
Johnson SM, Connelly S, Wilson IA, Kelly JW. Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors. Journal of Medicinal Chemistry. 51: 260-70. PMID 18095641 DOI: 10.1021/Jm0708735 |
0.31 |
|
2008 |
Bell CH, Pantophlet R, Schiefner A, Cavacini LA, Stanfield RL, Burton DR, Wilson IA. Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization. Journal of Molecular Biology. 375: 969-78. PMID 18068724 DOI: 10.1016/J.Jmb.2007.11.013 |
0.437 |
|
2008 |
Mathews II, McMullan D, Miller MD, Canaves JM, Elsliger MA, Floyd R, Grzechnik SK, Jaroszewski L, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, McPhillips TM, Morse AT, ... ... Wilson IA, et al. Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 A resolution. Proteins. 70: 603-8. PMID 18004772 DOI: 10.1002/Prot.21842 |
0.304 |
|
2007 |
Slabinski L, Jaroszewski L, Rodrigues APC, Rychlewski L, Wilson IA, Lesley SA, Godzik A. The challenge of protein structure determination - Lessons from structural genomics Protein Science. 16: 2472-2482. PMID 17962404 DOI: 10.1110/Ps.073037907 |
0.344 |
|
2007 |
Huang CC, Lam SN, Acharya P, Tang M, Xiang SH, Hussan SS, Stanfield RL, Robinson J, Sodroski J, Wilson IA, Wyatt R, Bewley CA, Kwong PD. Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. Science (New York, N.Y.). 317: 1930-4. PMID 17901336 DOI: 10.1126/Science.1145373 |
0.407 |
|
2007 |
Burton DR, Wilson IA. Immunology: Square-dancing antibodies Science. 317: 1507-1508. PMID 17872431 DOI: 10.1126/Science.1148905 |
0.321 |
|
2007 |
Stoll R, Lee BM, Debler EW, Laity JH, Wilson IA, Dyson HJ, Wright PE. Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA. Journal of Molecular Biology. 372: 1227-45. PMID 17716689 DOI: 10.1016/J.Jmb.2007.07.017 |
0.714 |
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2007 |
Huang S, Romanchuk G, Pattridge K, Lesley SA, Wilson IA, Matthews RG, Ludwig M. Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269. Protein Science : a Publication of the Protein Society. 16: 1588-95. PMID 17656578 DOI: 10.1110/Ps.072936307 |
0.348 |
|
2007 |
Xu Q, Saikatendu KS, Krishna SS, McMullan D, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL, Carlton D, Chiu HJ, Clayton T, DiDonato M, Duan L, Elsliger MA, ... ... Wilson IA, et al. Crystal structure of MtnX phosphatase from Bacillus subtilis at 2.0 angstroms resolution provides a structural basis for bipartite phosphomonoester hydrolysis of 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate. Proteins. 69: 433-9. PMID 17654724 DOI: 10.1002/Prot.21602 |
0.349 |
|
2007 |
Zubieta C, Joseph R, Krishna SS, McMullan D, Kapoor M, Axelrod HL, Miller MD, Abdubek P, Acosta C, Astakhova T, Carlton D, Chiu HJ, Clayton T, Deller MC, Duan L, ... ... Wilson IA, et al. Identification and structural characterization of heme binding in a novel dye-decolorizing peroxidase, TyrA. Proteins. 69: 234-43. PMID 17654547 DOI: 10.1002/Prot.21673 |
0.368 |
|
2007 |
Zubieta C, Krishna SS, Kapoor M, Kozbial P, McMullan D, Axelrod HL, Miller MD, Abdubek P, Ambing E, Astakhova T, Carlton D, Chiu HJ, Clayton T, Deller MC, Duan L, ... ... Wilson IA, et al. Crystal structures of two novel dye-decolorizing peroxidases reveal a beta-barrel fold with a conserved heme-binding motif. Proteins. 69: 223-33. PMID 17654545 DOI: 10.1002/Prot.21550 |
0.398 |
|
2007 |
Krishna SS, Tautz L, Xu Q, McMullan D, Miller MD, Abdubek P, Ambing E, Astakhova T, Axelrod HL, Carlton D, Chiu HJ, Clayton T, DiDonato M, Duan L, Elsliger MA, ... ... Wilson IA, et al. Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 angstroms resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases. Proteins. 69: 415-21. PMID 17636569 DOI: 10.1002/Prot.21314 |
0.353 |
|
2007 |
Zajonc DM, Wilson IA. Architecture of CD1 proteins Current Topics in Microbiology and Immunology. 314: 27-50. PMID 17593656 DOI: 10.1007/978-3-540-69511-0_2 |
0.348 |
|
2007 |
Sanguineti S, Centeno Crowley JM, Lodeiro Merlo MF, Cerutti ML, Wilson IA, Goldbaum FA, Stanfield RL, de Prat-Gay G. Specific Recognition of a DNA Immunogen by its Elicited Antibody Journal of Molecular Biology. 370: 183-195. PMID 17512945 DOI: 10.1016/J.Jmb.2007.04.046 |
0.389 |
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2007 |
Saphire EO, Montero M, Menendez A, van Houten NE, Irving MB, Pantophlet R, Zwick MB, Parren PW, Burton DR, Scott JK, Wilson IA. Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies. Journal of Molecular Biology. 369: 696-709. PMID 17445828 DOI: 10.1016/J.Jmb.2007.01.060 |
0.633 |
|
2007 |
Premkumar L, Rife CL, Sri Krishna S, McMullan D, Miller MD, Abdubek P, Ambing E, Astakhova T, Axelrod HL, Canaves JM, Carlton D, Chiu HJ, Clayton T, DiDonato M, Duan L, ... ... Wilson IA, et al. Crystal structure of TM1030 from Thermotoga maritima at 2.3 A resolution reveals molecular details of its transcription repressor function. Proteins. 68: 418-24. PMID 17444523 DOI: 10.1002/Prot.21436 |
0.324 |
|
2007 |
Debler EW, Kaufmann GF, Kirchdoerfer RN, Mee JM, Janda KD, Wilson IA. Crystal structures of a quorum-quenching antibody. Journal of Molecular Biology. 368: 1392-402. PMID 17400249 DOI: 10.1016/J.Jmb.2007.02.081 |
0.752 |
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2007 |
Xu L, Chong Y, Hwang I, D'Onofrio A, Amore K, Beardsley GP, Li C, Olson AJ, Boger DL, Wilson IA. Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase. The Journal of Biological Chemistry. 282: 13033-46. PMID 17324932 DOI: 10.1074/Jbc.M607293200 |
0.357 |
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2007 |
Nelson JD, Brunel FM, Jensen R, Crooks ET, Cardoso RM, Wang M, Hessell A, Wilson IA, Binley JM, Dawson PE, Burton DR, Zwick MB. An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10. Journal of Virology. 81: 4033-43. PMID 17287272 DOI: 10.1128/Jvi.02588-06 |
0.407 |
|
2007 |
Law M, Cardoso RM, Wilson IA, Burton DR. Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy. Journal of Virology. 81: 4272-85. PMID 17267498 DOI: 10.1128/Jvi.02536-06 |
0.409 |
|
2007 |
Stanfield RL, Dooley H, Verdino P, Flajnik MF, Wilson IA. Maturation of shark single-domain (IgNAR) antibodies: evidence for induced-fit binding. Journal of Molecular Biology. 367: 358-72. PMID 17258766 DOI: 10.1016/J.Jmb.2006.12.045 |
0.388 |
|
2007 |
Weekes D, Miller MD, Krishna SS, McMullan D, McPhillips TM, Acosta C, Canaves JM, Elsliger MA, Floyd R, Grzechnik SK, Jaroszewski L, Klock HE, Koesema E, Kovarik JS, Kreusch A, ... ... Wilson IA, et al. Crystal structure of a transcription regulator (TM1602) from Thermotoga maritima at 2.3 A resolution. Proteins. 67: 247-52. PMID 17256761 DOI: 10.1002/Prot.21221 |
0.309 |
|
2007 |
Müller R, Debler EW, Steinmann M, Seebeck FP, Wilson IA, Hilvert D. Bifunctional catalysis of proton transfer at an antibody active site. Journal of the American Chemical Society. 129: 460-1. PMID 17226987 DOI: 10.1021/Ja066578B |
0.739 |
|
2007 |
Cardoso RM, Brunel FM, Ferguson S, Zwick M, Burton DR, Dawson PE, Wilson IA. Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. Journal of Molecular Biology. 365: 1533-44. PMID 17125793 DOI: 10.1016/J.Jmb.2006.10.088 |
0.373 |
|
2007 |
Lazoura E, Lodding J, Farrugia W, Ramsland PA, Stevens J, Wilson IA, Pietersz GA, Apostolopoulos V. Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide. Immunology. 119: 306-16. PMID 17067310 DOI: 10.1111/J.1365-2567.2006.02434.X |
0.331 |
|
2007 |
Wilson IA. High throughput structural genomics and its general applicability to structural biology Acta Crystallographica Section a Foundations of Crystallography. 63: s13-s13. DOI: 10.1107/S0108767307099734 |
0.322 |
|
2006 |
Tian F, Debler EW, Millar DP, Deniz AA, Wilson IA, Schultz PG. The effects of antibodies on stilbene excited-state energetics. Angewandte Chemie (International Ed. in English). 45: 7763-5. PMID 17089439 DOI: 10.1002/Anie.200602720 |
0.694 |
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2006 |
Kosloff M, Han GW, Krishna SS, Schwarzenbacher R, Fasnacht M, Elsliger MA, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL, Canaves JM, Carlton D, Chiu HJ, Clayton T, ... ... Wilson IA, et al. Comparative structural analysis of a novel glutathioneS-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 A resolution. Proteins. 65: 527-37. PMID 16988933 DOI: 10.1002/Prot.21130 |
0.357 |
|
2006 |
Zajonc DM, Ainge GD, Painter GF, Severn WB, Wilson IA. Structural characterization of mycobacterial phosphatidylinositol mannoside binding to mouse CD1d. Journal of Immunology (Baltimore, Md. : 1950). 177: 4577-83. PMID 16982895 DOI: 10.4049/Jimmunol.177.7.4577 |
0.336 |
|
2006 |
Cooper ZD, Narasimhan D, Sunahara RK, Mierzejewski P, Jutkiewicz EM, Larsen NA, Wilson IA, Landry DW, Woods JH. Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase. Molecular Pharmacology. 70: 1885-91. PMID 16968810 DOI: 10.1124/Mol.106.025999 |
0.558 |
|
2006 |
Xu Q, Krishna SS, McMullan D, Schwarzenbacher R, Miller MD, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL, Canaves JM, Carlton D, Chiu HJ, Clayton T, DiDonato M, ... ... Wilson IA, et al. Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 A resolution reveals a fold similar to the Ran-binding protein Mog1p. Proteins. 65: 777-82. PMID 16948158 DOI: 10.1002/Prot.21015 |
0.369 |
|
2006 |
Mathews II, Krishna SS, Schwarzenbacher R, McMullan D, Jaroszewski L, Miller MD, Abdubek P, Agarwalla S, Ambing E, Axelrod HL, Canaves JM, Carlton D, Chiu HJ, Clayton T, DiDonato M, ... ... Wilson IA, et al. Crystal structure of phosphoribosylformyl-glycinamidine synthase II, PurS subunit (TM1244) from Thermotoga maritima at 1.90 A resolution. Proteins. 65: 249-54. PMID 16865708 DOI: 10.1002/Prot.21024 |
0.321 |
|
2006 |
Schwarzenbacher R, McMullan D, Krishna SS, Xu Q, Miller MD, Canaves JM, Elsliger MA, Floyd R, Grzechnik SK, Jaroszewski L, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, ... ... Wilson IA, et al. Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 A resolution reveals a new fold. Proteins. 65: 243-8. PMID 16865707 DOI: 10.1002/Prot.21058 |
0.316 |
|
2006 |
Binley JM, Ngo-Abdalla S, Moore P, Bobardt M, Chatterji U, Gallay P, Burton DR, Wilson IA, Elder JH, de Parseval A. Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120. Retrovirology. 3: 39. PMID 16817962 DOI: 10.1186/1742-4690-3-39 |
0.396 |
|
2006 |
Xu Q, Schwarzenbacher R, Krishna SS, McMullan D, Agarwalla S, Quijano K, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Elsliger MA, Grittini C, Grzechnik SK, ... ... Wilson IA, et al. Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 angstrom resolution. Proteins. 64: 808-13. PMID 16783794 DOI: 10.1002/Prot.20947 |
0.328 |
|
2006 |
Han GW, Sri Krishna S, Schwarzenbacher R, McMullan D, Ginalski K, Elsliger MA, Brittain SM, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod H, Canaves JM, Chiu HJ, DiDonato M, ... ... Wilson IA, et al. Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 A resolution. Proteins. 64: 1083-90. PMID 16779835 DOI: 10.1002/Prot.20950 |
0.34 |
|
2006 |
Stanfield RL, Gorny MK, Zolla-Pazner S, Wilson IA. Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity. Journal of Virology. 80: 6093-105. PMID 16731948 DOI: 10.1128/Jvi.00205-06 |
0.409 |
|
2006 |
Johnson MA, Peti W, Herrmann T, Wilson IA, Wüthrich K. Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence. Protein Science : a Publication of the Protein Society. 15: 1030-41. PMID 16597827 DOI: 10.1110/Ps.051964606 |
0.33 |
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2006 |
Rudolph MG, Stanfield RL, Wilson IA. How TCRs bind MHCs, peptides, and coreceptors. Annual Review of Immunology. 24: 419-66. PMID 16551255 DOI: 10.1146/Annurev.Immunol.23.021704.115658 |
0.394 |
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2006 |
Mathews II, Krishna SS, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, Hale J, ... ... Wilson IA, et al. Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution. Proteins. 63: 1106-11. PMID 16544324 DOI: 10.1002/Prot.20650 |
0.312 |
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2006 |
Jin KK, Krishna SS, Schwarzenbacher R, McMullan D, Abdubek P, Agarwalla S, Ambing E, Axelrod H, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Feuerhelm J, Godzik A, ... ... Wilson IA, et al. Crystal structure of TM1367 from Thermotoga maritima at 1.90 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold. Proteins. 63: 1112-8. PMID 16544291 DOI: 10.1002/Prot.20894 |
0.35 |
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2006 |
Stevens J, Blixt O, Tumpey TM, Taubenberger JK, Paulson JC, Wilson IA. Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus Science. 312: 404-410. PMID 16543414 DOI: 10.1126/Science.1124513 |
0.335 |
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2006 |
Wu D, Zajonc DM, Fujio M, Sullivan BA, Kinjo Y, Kronenberg M, Wilson IA, Wong CH. Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d. Proceedings of the National Academy of Sciences of the United States of America. 103: 3972-7. PMID 16537470 DOI: 10.1073/Pnas.0600285103 |
0.349 |
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2006 |
Zhu X, Wentworth P, Kyle RA, Lerner RA, Wilson IA. Cofactor-containing antibodies: crystal structure of the original yellow antibody. Proceedings of the National Academy of Sciences of the United States of America. 103: 3581-5. PMID 16537445 DOI: 10.1073/Pnas.0600251103 |
0.431 |
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2006 |
Shore DA, Teyton L, Dwek RA, Rudd PM, Wilson IA. Crystal Structure of the TCR Co-receptor CD8αα in Complex with Monoclonal Antibody YTS 105.18 Fab Fragment at 2.88 Å Resolution Journal of Molecular Biology. 358: 347-354. PMID 16530222 DOI: 10.1016/J.Jmb.2006.02.016 |
0.419 |
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2006 |
Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA. Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor. Proceedings of the National Academy of Sciences of the United States of America. 103: 2788-93. PMID 16477002 DOI: 10.1073/Pnas.0511161103 |
0.667 |
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2006 |
Zhu X, Dickerson TJ, Rogers CJ, Kaufmann GF, Mee JM, McKenzie KM, Janda KD, Wilson IA. Complete reaction cycle of a cocaine catalytic antibody at atomic resolution. Structure (London, England : 1993). 14: 205-16. PMID 16472740 DOI: 10.1016/J.Str.2005.10.014 |
0.323 |
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2006 |
Brunel FM, Zwick MB, Cardoso RM, Nelson JD, Wilson IA, Burton DR, Dawson PE. Structure-function analysis of the epitope for 4E10, a broadly neutralizing human immunodeficiency virus type 1 antibody. Journal of Virology. 80: 1680-7. PMID 16439525 DOI: 10.1128/Jvi.80.4.1680-1687.2006 |
0.411 |
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2006 |
DiDonato M, Krishna SS, Schwarzenbacher R, McMullan D, Jaroszewski L, Miller MD, Abdubek P, Agarwalla S, Ambing E, Axelrod H, Biorac T, Chiu HJ, Deacon AM, Elsliger MA, Feuerhelm J, ... ... Wilson IA, et al. Crystal structure of a single-stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 A resolution. Proteins. 63: 256-60. PMID 16435371 DOI: 10.1002/Prot.20841 |
0.344 |
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2006 |
Scanlan C, Calarese D, Lee HK, Blixt O, Wong CH, Wilson I, Burton D, Dwek R, Rudd P. Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design. Advances in Experimental Medicine and Biology. 564: 7-8. PMID 16400800 DOI: 10.1007/0-387-25515-X_4 |
0.806 |
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2006 |
Stevens J, Blixt O, Glaser L, Taubenberger JK, Palese P, Paulson JC, Wilson IA. Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities. Journal of Molecular Biology. 355: 1143-55. PMID 16343533 DOI: 10.1016/J.Jmb.2005.11.002 |
0.337 |
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2006 |
Xu Q, Schwarzenbacher R, McMullan D, Abdubek P, Agarwalla S, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Wilson IA, et al. Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 A resolution reveals a new fold. Proteins. 62: 292-6. PMID 16287129 DOI: 10.1002/Prot.20611 |
0.324 |
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2006 |
Lesley SA, Wilson IA. Protein production and crystallization at the joint center for structural genomics. Journal of Structural and Functional Genomics. 6: 71-9. PMID 16211502 DOI: 10.1007/S10969-005-2897-2 |
0.315 |
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2006 |
Stanfield RL, Wilson IA. Structural studies of human HIV-1 V3 antibodies Human Antibodies. 14: 73-80. DOI: 10.3233/Hab-2005-143-404 |
0.393 |
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2006 |
Verdino P, Aldag C, Hilvert D, Wilson IA. Antibodies: specificity and promiscuity of ligand recognition Acta Crystallographica Section a Foundations of Crystallography. 62: s38-s38. DOI: 10.1107/S0108767306099247 |
0.43 |
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2005 |
Zajonc DM, Maricic I, Wu D, Halder R, Roy K, Wong CH, Kumar V, Wilson IA. Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity. The Journal of Experimental Medicine. 202: 1517-26. PMID 16314439 DOI: 10.1084/Jem.20051625 |
0.352 |
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2005 |
Huang CC, Tang M, Zhang MY, Majeed S, Montabana E, Stanfield RL, Dimitrov DS, Korber B, Sodroski J, Wilson IA, Wyatt R, Kwong PD. Structural biology: Structure of a V3-containing HIV-1 gp120 core Science. 310: 1025-1028. PMID 16284180 DOI: 10.1126/Science.1118398 |
0.401 |
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2005 |
Klock HE, Schwarzenbacher R, Xu Q, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Wilson IA, et al. Crystal structure of a conserved hypothetical protein (gi: 13879369) from Mouse at 1.90 A resolution reveals a new fold. Proteins. 61: 1132-6. PMID 16224779 DOI: 10.1002/Prot.20610 |
0.354 |
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2005 |
Burton DR, Stanfield RL, Wilson IA. Antibody vs. HIV in a clash of evolutionary titans. Proceedings of the National Academy of Sciences of the United States of America. 102: 14943-8. PMID 16219699 DOI: 10.1073/Pnas.0505126102 |
0.425 |
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