Rajendra G. Mehta - Publications

Affiliations: 
Illinois Institute of Technology, Chicago, IL, United States 
Area:
Biochemistry, Cell Biology, Biomedical Engineering
Website:
https://science.iit.edu/people/faculty/rajendra-mehta

142 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Singh S, Murillo G, Richner J, Singh SP, Berleth E, Kumar V, Mehta R, Ramiya V, Parihar AS. A Broad-Based Characterization of a Cell-Penetrating, Single Domain Camelid Bi-Specific Antibody Monomer That Targets STAT3 and KRAS Dependent Cancers. International Journal of Molecular Sciences. 23. PMID 35886918 DOI: 10.3390/ijms23147565  0.329
2020 Gupta A, Gupta G, Mehta RR, Ivancic DZ, Walker RR, Patel JR, Gallegos KM, Davidson AM, Khan SA, Mehta RG, Tilghman SL. A novel and cost-effective ex vivo orthotopic model for the study of human breast cancer in mouse mammary gland organ culture. Biology Open. PMID 34004720 DOI: 10.1242/bio.051649  0.673
2020 Gupta A, Gupta G, Mehta RR, Ivancic DZ, Walker RR, Patel JR, Gallegos KM, Davidson AM, Khan SA, Mehta RG, Tilghman SL. A novel and cost-effective orthotopic model for the study of human breast cancer in mouse mammary gland organ culture. Biology Open. PMID 32366373 DOI: 10.1242/Bio.051649  0.701
2019 Singh S, Murillo G, Singh A, Singh S, Parihar M, Singh A, Mehta R, Parihar A. Abstract 1544: Cell penetrating single domain antibody (sdAb) SBT-100 binds KRAS and inhibits growth of human cancers with KRAS activating mutations Cancer Research. 79: 1544-1544. DOI: 10.1158/1538-7445.Am2019-1544  0.409
2018 Kaur P, Robin, Mehta RG, Arora S, Singh B. Progression of conventional hepatic cell culture models to bioengineered HepG2 cells for evaluation of herbal bioactivities. Biotechnology Letters. PMID 29616383 DOI: 10.1007/S10529-018-2547-Y  0.44
2018 Singh S, Murillo G, Singh A, Singh S, Parihar M, Mehta R, Singh A, Parihar A. Abstract 5436: Novel single-domain antibody (sdAb), SBT-100, localizes in the cytoplasm to inhibit IL-6 mediated P-STAT3 nuclear translocation in cancer cells Cancer Research. 78: 5436-5436. DOI: 10.1158/1538-7445.Am2018-5436  0.395
2017 Singh S, Murillo G, Singh A, Singh S, Parihar MS, Singh AH, Mehta R, Parihar AS. Effect of KRAS and P-STAT3 inhibition by SBT-100 on gemcitabine and pancreatic cancer growth in vivo. Journal of Clinical Oncology. 35. DOI: 10.1200/Jco.2017.35.15_Suppl.E15727  0.418
2017 Singh S, Murillo G, Singh A, Singh S, Parihar MS, Singh AH, Mehta R, Parihar AS. Single domain antibody (SBT-100) crosses the blood brain barrier (BBB) and inhibits human glioblastoma by selectively targeting KRAS and P-STAT3. Journal of Clinical Oncology. 35. DOI: 10.1200/Jco.2017.35.15_Suppl.E13547  0.323
2017 Singh S, Murillo G, Chen D, Singh A, Mehta R, Parihar A. Abstract P6-12-13: Single domain antibody (SBT-100) inhibits growth of human HER2+ and triple negative breast cancers (TNBC) in xenografts by binding STAT3 and P-STAT3 Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P6-12-13  0.494
2017 Singh S, Murillo G, Rom A, Singh A, Singh S, Parihar M, Chen D, Mehta R, Baker R, Singh A, Parihar AS. Abstract 4699: Single domain antibody (sdAb) localizes in cancer cells to inhibit signal transducer and activator of transcription 3 (STAT3) resulting in therapeutic inhibition of multiple cancers Cancer Research. 77: 4699-4699. DOI: 10.1158/1538-7445.Am2017-4699  0.469
2016 Alimirah F, Peng X, Gupta A, Yuan L, Welsh J, Cleary M, Mehta RG. Crosstalk between the vitamin D receptor (VDR) and miR-214 in regulating SuFu, a hedgehog pathway inhibitor in breast cancer cells. Experimental Cell Research. PMID 27693451 DOI: 10.1016/J.Yexcr.2016.08.012  0.767
2016 Mehta R, Montembault M, Warren F, Gupta A, Brealey N, Moore A. Systemic Exposures of Fluticasone Propionate and Salmeterol Following Inhalation via Metered Dose Inhaler with the Mini Spacer Compared with the Aerochamber Plus Spacer. Journal of Aerosol Medicine and Pulmonary Drug Delivery. PMID 26824933 DOI: 10.1089/jamp.2015.1236  0.478
2016 Singh S, Murillo G, Mehta R, Chen D, Singh A, Singh S, Singh A, Parihar AS. A novel single domain antibody (sdAb) SBT-100 targeting intracellular STAT3 to inhibit major subtypes of human breast cancer. Journal of Clinical Oncology. 34. DOI: 10.1200/Jco.2016.34.15_Suppl.E14000  0.472
2016 Singh S, Murillo G, Mehta R, Chen D, Singh A, Singh S, Singh A, Parihar AS. A novel single domain antibody (sdAb) SBT-100 to target intracellular STAT3 to affect growth and regression of human triple negative breast cancer (TNBC) cells. Journal of Clinical Oncology. 34: 1083-1083. DOI: 10.1200/Jco.2016.34.15_Suppl.1083  0.431
2015 Brealey N, Gupta A, Renaux J, Mehta R, Allen A, Henderson A. Pharmacokinetics of fluticasone furoate, umeclidinium, and vilanterol as a triple therapy in healthy volunteers. International Journal of Clinical Pharmacology and Therapeutics. PMID 26227101 DOI: 10.5414/CP202390  0.477
2015 Mehta R, Riddell K, Gupta A, Louey MD, Chan RH. Comparison of the Pharmacokinetics of Salmeterol and Fluticasone Propionate 50/100 µg Delivered in Combination as a Dry Powder Via a Capsule-Based Inhaler and a Multi-Dose Inhaler. Clinical Drug Investigation. 35: 319-26. PMID 25805608 DOI: 10.1007/s40261-015-0282-x  0.478
2014 Mehta RG, Hawthorne M, Mehta RR, Torres KE, Peng X, McCormick DL, Kopelovich L. Differential roles of ERα and ERβ in normal and neoplastic development in the mouse mammary gland. Plos One. 9: e113175. PMID 25405629 DOI: 10.1371/Journal.Pone.0113175  0.367
2014 Mehta RG. Current paradigms of cancer chemoprevention Turkish Journal of Biology. 38: 839-847. DOI: 10.3906/Biy-1405-42  0.343
2014 Mehta RG, Hawthorne M, Mehta RR, Torres KEO, Peng X, McCormick DL, Kopelovich L. Effects of pretreatment with EGF and progesterone on the mammary gland development in MMOC. Plos One. DOI: 10.1371/Journal.Pone.0113175.G002  0.319
2013 Peng X, Li W, Yuan L, Mehta RG, Kopelovich L, McCormick DL. Inhibition of proliferation and induction of autophagy by atorvastatin in PC3 prostate cancer cells correlate with downregulation of Bcl2 and upregulation of miR-182 and p21. Plos One. 8: e70442. PMID 23936432 DOI: 10.1371/Journal.Pone.0070442  0.347
2013 Mehta R, Katta H, Alimirah F, Patel R, Murillo G, Peng X, Muzzio M, Mehta RG. Deguelin action involves c-Met and EGFR signaling pathways in triple negative breast cancer cells. Plos One. 8: e65113. PMID 23762292 DOI: 10.1371/Journal.Pone.0065113  0.76
2013 Mehta RR, Katta H, Kalra A, Patel R, Gupta A, Alimirah F, Murillo G, Peng X, Unni A, Muzzio M, Mehta RG. Efficacy and mechanism of action of Deguelin in suppressing metastasis of 4T1 cells. Clinical & Experimental Metastasis. 30: 855-66. PMID 23645347 DOI: 10.1007/S10585-013-9585-6  0.799
2013 Mehta RG, Peng X, Alimirah F, Murillo G, Mehta R. Vitamin D and breast cancer: emerging concepts. Cancer Letters. 334: 95-100. PMID 23142286 DOI: 10.1016/J.Canlet.2012.10.034  0.74
2013 Mehta RG, Peng X, Roy S, Hawthorne M, Kalra A, Alimirah F, Mehta RR, Kopelovich L. PPARγ antagonist GW9662 induces functional estrogen receptor in mouse mammary organ culture: Potential translational significance Molecular and Cellular Biochemistry. 372: 249-256. PMID 23001870 DOI: 10.1007/S11010-012-1466-9  0.759
2013 Gupta A, Mehta R, Alimirah F, Peng X, Murillo G, Wiehle R, Mehta RG. Efficacy and mechanism of action of Proellex, an antiprogestin in aromatase overexpressing and Letrozole resistant T47D breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 133: 30-42. PMID 22939887 DOI: 10.1016/J.Jsbmb.2012.08.004  0.785
2012 Alimirah F, Peng X, Yuan L, Mehta RR, von Knethen A, Choubey D, Mehta RG. Crosstalk between the peroxisome proliferator-activated receptor γ (PPARγ) and the vitamin D receptor (VDR) in human breast cancer cells: PPARγ binds to VDR and inhibits 1α,25-dihydroxyvitamin D3 mediated transactivation. Experimental Cell Research. 318: 2490-7. PMID 22884583 DOI: 10.1016/J.Yexcr.2012.07.020  0.746
2012 Saleiro D, Murillo G, Benya RV, Bissonnette M, Hart J, Mehta RG. Estrogen receptor-β protects against colitis-associated neoplasia in mice. International Journal of Cancer. Journal International Du Cancer. 131: 2553-61. PMID 22488198 DOI: 10.1002/Ijc.27578  0.723
2012 Peng X, Tiwari N, Roy S, Yuan L, Murillo G, Mehta RR, Benya RV, Mehta RG. Regulation of CYP24 splicing by 1,25-dihydroxyvitamin D₃ in human colon cancer cells. The Journal of Endocrinology. 212: 207-15. PMID 22068926 DOI: 10.1530/Joe-11-0305  0.403
2012 Peng X, Yuan L, Fatouma A, Mehta R, Kopelovich L, McCormick DL. Abstract 613: Synergistic antiproliferative activity of combined administration of atorvastatin and zoledronic acid in LNCaP and PC3 prostate cancer cells Cancer Research. 72: 613-613. DOI: 10.1158/1538-7445.Am2012-613  0.422
2012 Alimirah F, Mehta RR, Peng X, Mehta RG. Abstract 573: Deguelin inhibits the expression of estrogen receptor alpha in human breast cancer cells Cancer Research. 72: 573-573. DOI: 10.1158/1538-7445.Am2012-573  0.779
2012 Kalra AP, Gupta A, Patel R, Katta H, Hawthorne M, Murillo G, Mehta R, Mehta R. Abstract 3829: Inhibition of breast cancer metastasis by deguelin in an experimental model Cancer Research. 72: 3829-3829. DOI: 10.1158/1538-7445.Am2012-3829  0.679
2012 Mehta R, Alimirah F, Gupta A, Kalra A, Mehta R. Abstract 3812: Deguelin as a novel therapeutic agent for Herceptin resistant breast cancers Cancer Research. 72: 3812-3812. DOI: 10.1158/1538-7445.Am2012-3812  0.808
2012 Gupta A, Mehta RR, Wiehle R, Hawthorne M, Mehta RG. Abstract 3275: Development of a newex-vivoorthotopic model-Human breast cancer cells in mouse mammary gland organ culture Cancer Research. 72: 3275-3275. DOI: 10.1158/1538-7445.Am2012-3275  0.705
2012 Mehta RG, Peng X, Roy S, Mehta R, Kopelovich L. Abstract 2580: Induction of estrogen receptor alpha by GW9662 sensitizes mammary glands to tamoxifen treatment in organ culture Cancer Research. 72: 2580-2580. DOI: 10.1158/1538-7445.Am2012-2580  0.468
2012 Saleiro D, Murillo G, Hawthorne M, Mehta R. Abstract 1631: Protection of colon carcinogenesis by estrogen receptor-beta may involve regulation of angiogenesis and invasion specific signaling molecules Cancer Research. 72: 1631-1631. DOI: 10.1158/1538-7445.Am2012-1631  0.733
2011 Swarup VP, Huang Y, Murillo G, Saleiro D, Mehta RG, Bishnoi SW. Modeling the cellular impact of nanoshell-based biosensors using mouse alveolar macrophage cultures. Metallomics : Integrated Biometal Science. 3: 1218-26. PMID 21858295 DOI: 10.1039/C1Mt00089F  0.681
2011 Alimirah F, Peng X, Murillo G, Mehta RG. Functional significance of vitamin D receptor FokI polymorphism in human breast cancer cells. Plos One. 6: e16024. PMID 21283672 DOI: 10.1371/Journal.Pone.0016024  0.74
2011 Saleiro D, Murillo G, Mutreja K, Hawthorne M, Mehta RG. Abstract 5590: Role of estrogen receptor-beta in colitis-associated cancer Cancer Research. 71: 5590-5590. DOI: 10.1158/1538-7445.Am2011-5590  0.733
2011 Peng X, Alimirah F, Roy S, Yuan L, Murillo G, Mehta RR, Mehta RG. Abstract 456: 25-Hydroxyvitamin D3 inhibits clonogenic growth and regulates expression of multiple cytokines/chemokines in co-culture of colon cancer and macrophage-like THP-1 cells Cancer Research. 71: 456-456. DOI: 10.1158/1538-7445.Am2011-456  0.752
2011 Kakarala M, Dubey SK, Dobry CJ, Peng X, Murillo G, Parikh SR, Amarasinghe C, Mehta R, Brenner DE. Abstract 1842: Vitamin D compounds induce BRCA1 expression and inhibit breast stem cells Cancer Research. 71: 1842-1842. DOI: 10.1158/1538-7445.Am2011-1842  0.448
2010 Mehta RR, Hawthorne M, Peng X, Shilkaitis A, Mehta RG, Beattie CW, Das Gupta TK. A 28-amino-acid peptide fragment of the cupredoxin azurin prevents carcinogen-induced mouse mammary lesions. Cancer Prevention Research (Philadelphia, Pa.). 3: 1351-60. PMID 20841487 DOI: 10.1158/1940-6207.Capr-10-0024  0.417
2010 Saleiro D, Murillo G, Lubahn DB, Kopelovich L, Korach KS, Mehta RG. Enhanced induction of mucin-depleted foci in estrogen receptor {beta} knockout mice. Cancer Prevention Research (Philadelphia, Pa.). 3: 1198-204. PMID 20716634 DOI: 10.1158/1940-6207.Capr-10-0044  0.714
2010 Peng X, Vaishnav A, Murillo G, Alimirah F, Torres KE, Mehta RG. Protection against cellular stress by 25-hydroxyvitamin D3 in breast epithelial cells. Journal of Cellular Biochemistry. 110: 1324-33. PMID 20564226 DOI: 10.1002/Jcb.22646  0.726
2010 Alimirah F, Vaishnav A, McCormick M, Echchgadda I, Chatterjee B, Mehta RG, Peng X. Functionality of unliganded VDR in breast cancer cells: repressive action on CYP24 basal transcription. Molecular and Cellular Biochemistry. 342: 143-50. PMID 20440542 DOI: 10.1007/S11010-010-0478-6  0.75
2010 Mehta RG, Murillo G, Naithani R, Peng X. Cancer chemoprevention by natural products: how far have we come? Pharmaceutical Research. 27: 950-61. PMID 20238150 DOI: 10.1007/S11095-010-0085-Y  0.356
2010 Thoennissen NH, O'Kelly J, Lu D, Iwanski GB, La DT, Abbassi S, Leiter A, Karlan B, Mehta R, Koeffler HP. Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway. Oncogene. 29: 285-96. PMID 19855437 DOI: 10.1038/Onc.2009.335  0.526
2010 Saleiro D, Murillo G, Kopelovich L, Mehta RG. Abstract 940: Mucin depleted foci as a biomarker for colon precancerous lesions in estrogen receptor β knockout mice Cancer Research. 70: 940-940. DOI: 10.1158/1538-7445.Am10-940  0.727
2010 Alimirah F, Mehta RG, Peng X. Abstract 5718: Convergence of vitamin D and PPARγ signaling in human breast cancer cell lines Cancer Research. 70: 5718-5718. DOI: 10.1158/1538-7445.Am10-5718  0.768
2010 Kanade GG, Nathani R, Huma L, Mehta RG, Murillo G. Abstract 5694: Zapotin mediates its action by inducing p53 in wild-type p53 positive human lung cancer cells Cancer Research. 70: 5694-5694. DOI: 10.1158/1538-7445.Am10-5694  0.409
2010 Gupta A, Peng X, Murillo G, Mehta RR, Wiehle R, Mehta RG. Abstract 5691: Significance of combination treatment of antiprogestin and aromatase inhibitors in aromatase overexpressing T47D breast cancer cells Cancer Research. 70: 5691-5691. DOI: 10.1158/1538-7445.Am10-5691  0.669
2009 Murillo G, Peng X, Torres KE, Mehta RG. Deguelin inhibits growth of breast cancer cells by modulating the expression of key members of the Wnt signaling pathway. Cancer Prevention Research (Philadelphia, Pa.). 2: 942-50. PMID 19861542 DOI: 10.1158/1940-6207.Capr-08-0232  0.494
2009 Hussain-Hakimjee EA, Mehta RG. Regulation of steroid receptor expression by 1alpha-hydroxyvitamin D5 in hormone-responsive breast cancer cells. Anticancer Research. 29: 3555-61. PMID 19667148  0.337
2009 Peng X, Hawthorne M, Vaishnav A, St-Arnaud R, Mehta RG. 25-Hydroxyvitamin D3 is a natural chemopreventive agent against carcinogen induced precancerous lesions in mouse mammary gland organ culture. Breast Cancer Research and Treatment. 113: 31-41. PMID 18205042 DOI: 10.1007/S10549-008-9900-0  0.413
2008 Mehta RG, Naithani R, Huma L, Hawthorne M, Moriarty RM, McCormick DL, Steele VE, Kopelovich L. Efficacy of chemopreventive agents in mouse mammary gland organ culture (MMOC) model: a comprehensive review. Current Medicinal Chemistry. 15: 2785-825. PMID 18991637 DOI: 10.2174/092986708786242787  0.41
2008 Naithani R, Huma LC, Moriarty RM, McCormick DL, Mehta RG. Comprehensive review of cancer chemopreventive agents evaluated in experimental carcinogenesis models and clinical trials. Current Medicinal Chemistry. 15: 1044-71. PMID 18473802 DOI: 10.2174/092986708784221403  0.398
2008 Murillo G, Naithani R, Mehta RG. Efficacy of herbal products in colorectal cancer prevention Current Colorectal Cancer Reports. 4: 34-42. DOI: 10.1007/S11888-008-0007-0  0.369
2007 Whyte L, Huang YY, Torres K, Mehta RG. Molecular mechanisms of resveratrol action in lung cancer cells using dual protein and microarray analyses. Cancer Research. 67: 12007-17. PMID 18089832 DOI: 10.1158/0008-5472.Can-07-2464  0.399
2007 Wiehle RD, Christov K, Mehta R. Anti-progestins suppress the growth of established tumors induced by 7,12-dimethylbenz(a)anthracene: comparison between RU486 and a new 21-substituted-19-nor-progestin. Oncology Reports. 18: 167-74. PMID 17549364  0.777
2007 Murillo G, Hirschelman WH, Ito A, Moriarty RM, Kinghorn AD, Pezzuto JM, Mehta RG. Zapotin, a phytochemical present in a Mexican fruit, prevents colon carcinogenesis. Nutrition and Cancer. 57: 28-37. PMID 17516860 DOI: 10.1080/01635580701268097  0.406
2007 Murillo G, Matusiak D, Benya RV, Mehta RG. Chemopreventive efficacy of 25-hydroxyvitamin D3 in colon cancer. The Journal of Steroid Biochemistry and Molecular Biology. 103: 763-7. PMID 17257827 DOI: 10.1016/J.Jsbmb.2006.12.074  0.413
2007 Peng X, Mehta RG. Differential expression of prohibitin is correlated with dual action of Vitamin D as a proliferative and antiproliferative hormone in breast epithelial cells. The Journal of Steroid Biochemistry and Molecular Biology. 103: 446-50. PMID 17207617 DOI: 10.1016/J.Jsbmb.2006.11.017  0.415
2007 Peng X, Jhaveri P, Hussain-Hakimjee EA, Mehta RG. Overexpression of ER and VDR is not sufficient to make ER-negative MDA-MB231 breast cancer cells responsive to 1alpha-hydroxyvitamin D5. Carcinogenesis. 28: 1000-7. PMID 17130524 DOI: 10.1093/carcin/bgl230  0.349
2007 Zhang X, Mehta RG, Lantvit DD, Coschigano KT, Kopchick JJ, Green JE, Hedayat S, Christov KT, Ray VH, Unterman TG, Swanson SM. Inhibition of estrogen-independent mammary carcinogenesis by disruption of growth hormone signaling. Carcinogenesis. 28: 143-50. PMID 16916863 DOI: 10.1093/Carcin/Bgl138  0.363
2007 Wiehle RD, Christov K, Mehta R. Anti-progestins suppress the growth of established tumors induced by 7,12-dimethylbenz(a)anthracene: Comparison between RU486 and a new 21-substituted-19-nor-progestin Oncology Reports. 18: 167-174. DOI: 10.3892/Or.18.1.167  0.372
2006 Choi JK, Murillo G, Su BN, Pezzuto JM, Kinghorn AD, Mehta RG. Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells. The Febs Journal. 273: 5714-23. PMID 17212786 DOI: 10.1111/J.1742-4658.2006.05560.X  0.43
2006 Vijayakumar S, Boerner PS, Mehta RR, Packianathan S, Mehta RG, Das Gupta TK. Clinical trials using chemopreventive vitamin D analogs in breast cancer. Cancer Journal (Sudbury, Mass.). 12: 445-50. PMID 17207311 DOI: 10.1097/00130404-200611000-00001  0.44
2006 Peng X, Mehta R, Wang S, Chellappan S, Mehta RG. Prohibitin is a novel target gene of vitamin D involved in its antiproliferative action in breast cancer cells. Cancer Research. 66: 7361-9. PMID 16849588 DOI: 10.1158/0008-5472.Can-06-1004  0.447
2006 Jung HA, Su BN, Keller WJ, Mehta RG, Kinghorn AD. Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen) Journal of Agricultural and Food Chemistry. 54: 2077-2082. PMID 16536578 DOI: 10.1021/Jf052649Z  0.313
2006 Hussain-Hakimjee EA, Peng X, Mehta RR, Mehta RG. Growth inhibition of carcinogen-transformed MCF-12F breast epithelial cells and hormone-sensitive BT-474 breast cancer cells by 1alpha-hydroxyvitamin D5. Carcinogenesis. 27: 551-9. PMID 16195238 DOI: 10.1093/Carcin/Bgi231  0.46
2005 Vijayakumar S, Mehta RR, Boerner PS, Packianathan S, Mehta RG. Clinical trials involving vitamin D analogs in prostate cancer. Cancer Journal (Sudbury, Mass.). 11: 362-73. PMID 16259866 DOI: 10.1097/00130404-200509000-00002  0.346
2005 Murillo G, Mehta RG. Chemoprevention of chemically-induced mammary and colon carcinogenesis by 1alpha-hydroxyvitamin D5. The Journal of Steroid Biochemistry and Molecular Biology. 97: 129-36. PMID 16051482 DOI: 10.1016/J.Jsbmb.2005.06.008  0.375
2005 Chow AW, Murillo G, Yu C, Van Breemen RB, Boddie AW, Pezzuto JM, Das Gupta TK, Mehta RG. Resveratrol inhibits rhabdomyosarcoma cell proliferation European Journal of Cancer Prevention. 14: 351-356. PMID 16030425 DOI: 10.1097/00008469-200508000-00007  0.396
2005 Peng X, Mehta RG, Tonetti DA, Christov K. Identification of novel RARbeta2 transcript variants with short 5'-UTRs in normal and cancerous breast epithelial cells. Oncogene. 24: 1296-301. PMID 15558014 DOI: 10.1038/Sj.Onc.1208284  0.41
2004 Packianathan S, Mehta RG, Mehta RR, Hall WH, Boerner PS, Beckett LA, Vijayakumar S. Designing a randomized phase I/II prostate cancer chemoprevention trial using 1alpha-hydroxy-24-ethyl-cholecalciferol, an analogue of vitamin D3. Cancer Journal (Sudbury, Mass.). 10: 357-67. PMID 15701267 DOI: 10.1097/00130404-200411000-00005  0.323
2004 Swamy N, Chen TC, Peleg S, Dhawan P, Christakos S, Stewart LV, Weigel NL, Mehta RG, Holick MF, Ray R. Inhibition of proliferation and induction of apoptosis by 25-hydroxyvitamin D3-3beta-(2)-Bromoacetate, a nontoxic and vitamin D receptor-alkylating analog of 25-hydroxyvitamin D3 in prostate cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8018-27. PMID 15585637 DOI: 10.1158/1078-0432.Ccr-04-0881  0.38
2004 Mehta R, Lansky EP. Breast cancer chemopreventive properties of pomegranate (Punica granatum) fruit extracts in a mouse mammary organ culture. European Journal of Cancer Prevention. 13: 345-348. PMID 15554563 DOI: 10.1097/01.Cej.0000136571.70998.5A  0.449
2004 Gafner S, Lee SK, Cuendet M, Barthélémy S, Vergnes L, Labidalle S, Mehta RG, Boone CW, Pezzuto JM. Biologic evaluation of curcumin and structural derivatives in cancer chemoprevention model systems Phytochemistry. 65: 2849-2859. PMID 15501252 DOI: 10.1016/J.Phytochem.2004.08.008  0.336
2004 Mehta RG. Stage-specific inhibition of mammary carcinogenesis by 1alpha-hydroxyvitamin D5. European Journal of Cancer (Oxford, England : 1990). 40: 2331-7. PMID 15454260 DOI: 10.1016/J.Ejca.2004.05.025  0.365
2003 Jang DS, Park EJ, Kang YH, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Potential cncer chemopreventive flavonoids from the stems of Tephrosia toxicaria. Journal of Natural Products. 66: 1166-70. PMID 14510590 DOI: 10.1021/Np0302100  0.329
2003 Jang DS, Park EJ, Kang YH, Su BN, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Compounds obtained from sida acuta with the potential to induce quinone reductase and to inhibit 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesions in a mouse mammary organ culture model. Archives of Pharmacal Research. 26: 585-90. PMID 12967190 DOI: 10.1007/Bf02976704  0.304
2003 Hussain EA, Mehta RR, Ray R, Das Gupta TK, Mehta RG. Efficacy and mechanism of action of 1alpha-hydroxy-24-ethyl-cholecalciferol (1alpha[OH]D5) in breast cancer prevention and therapy. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 164: 393-411. PMID 12899538 DOI: 10.1007/978-3-642-55580-0_29  0.447
2003 Jang DS, Park EJ, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Santarsiero BD, Mesecar AD, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Potential cancer chemopreventive constituents of the seeds of Dipteryx odorata (tonka bean). Journal of Natural Products. 66: 583-7. PMID 12762787 DOI: 10.1021/Np020522N  0.306
2003 Mehta RG, Hussain EA, Mehta RR, Das Gupta TK. Chemoprevention of mammary carcinogenesis by 1alpha-hydroxyvitamin D5, a synthetic analog of Vitamin D. Mutation Research. 523: 253-64. PMID 12628523 DOI: 10.1016/S0027-5107(02)00341-X  0.437
2003 Murillo G, Kosmeder JW, Pezzuto JM, Mehta RG. Deguelin suppresses the formation of carcinogen-induced aberrant crypt foci in the colon of CF-1 mice. International Journal of Cancer. 104: 7-11. PMID 12532413 DOI: 10.1002/Ijc.10901  0.335
2003 Murillo G, Salti GI, Kosmeder JW, Pezzuto JM, Mehta RG. Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest. European Journal of Cancer (Oxford, England : 1990). 38: 2446-54. PMID 12460790 DOI: 10.1016/S0959-8049(02)00192-2  0.415
2002 Chatterton RT, Lydon JP, Mehta RG, Mateo ET, Pletz A, Jordan VC. Role of the progesterone receptor (PR) in susceptibility of mouse mammary gland to 7,12-dimethylbenz[a]anthracene-induced hormone-independent preneoplastic lesions in vitro. Cancer Letters. 188: 47-52. PMID 12406547 DOI: 10.1016/S0304-3835(02)00461-5  0.345
2002 Jang DS, Park EJ, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Santarsiero BD, Mesecar AD, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Constituents of Musa x paradisiaca cultivar with the potential to induce the phase II enzyme, quinone reductase. Journal of Agricultural and Food Chemistry. 50: 6330-4. PMID 12381112 DOI: 10.1021/Jf0206670  0.305
2002 Mehta RG, Pezzuto JM. Discovery of cancer preventive agents from natural products: from plants to prevention. Current Oncology Reports. 4: 478-86. PMID 12354359 DOI: 10.1007/S11912-002-0059-2  0.39
2002 Su BN, Chang LC, Park EJ, Cuendet M, Santarsiero BD, Mesecar AD, Mehta RG, Fong HH, Pezzuto JM, Kinghorn AD. Bioactive constituents of the seeds of Brucea javanica. Planta Medica. 68: 730-3. PMID 12221597 DOI: 10.1055/S-2002-33798  0.306
2002 Rimando AM, Cuendet M, Desmarchelier C, Mehta RG, Pezzuto JM, Duke SO. Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol. Journal of Agricultural and Food Chemistry. 50: 3453-7. PMID 12033810 DOI: 10.1021/Jf0116855  0.309
2002 Mehta RG, Mehta RR. Vitamin D and cancer. The Journal of Nutritional Biochemistry. 13: 252-264. PMID 12015155 DOI: 10.1016/S0955-2863(02)00183-3  0.383
2002 Kim ND, Mehta R, Yu W, Neeman I, Livney T, Amichay A, Poirier D, Nicholls P, Kirby A, Jiang W, Mansel R, Ramachandran C, Rabi T, Kaplan B, Lansky E. Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer. Breast Cancer Research and Treatment. 71: 203-17. PMID 12002340 DOI: 10.1023/A:1014405730585  0.442
2002 Gu JQ, Gills JJ, Park EJ, Mata-Greenwood E, Hawthorne ME, Axelrod F, Chavez PI, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Sesquiterpenoids from Tithonia diversifolia with potential cancer chemopreventive activity. Journal of Natural Products. 65: 532-6. PMID 11975495 DOI: 10.1021/Np010545M  0.337
2002 Mehta RR, Bratescu L, Graves JM, Shilkaitis A, Green A, Mehta RG, Gupta TKD. In vitro transformation of human congenital naevus to malignant melanoma. Melanoma Research. 12: 27-33. PMID 11828255 DOI: 10.1097/00008390-200202000-00005  0.347
2002 Hawthorne M, Steele V, Mehta RG. Evaluation of Selected Chemopreventive Agents Present in Common Foods in Mouse Mammary Gland Organ Culture Pharmaceutical Biology. 40: 70-74. DOI: 10.1076/Phbi.40.7.70.9175  0.359
2001 Murillo G, Mehta RG. Cruciferous Vegetables and Cancer Prevention Nutrition and Cancer. 41: 17-28. PMID 12094621 DOI: 10.1080/01635581.2001.9680607  0.367
2001 Waffo-Téguo P, Hawthorne ME, Cuendet M, Mérillon JM, Kinghorn AD, Pezzuto JM, Mehta RG. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutrition and Cancer. 40: 173-9. PMID 11962253 DOI: 10.1207/S15327914Nc402_14  0.345
2001 Mata-Greenwood E, Daeuble JF, Grieco PA, Dou J, McChesney JD, Mehta RG, Kinghorn AD, Pezzuto JM. Novel esters of glaucarubolone as inducers of terminal differentiation of promyelocytic HL-60 cells and inhibitors of 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesion formation in mouse mammary organ culture. Journal of Natural Products. 64: 1509-13. PMID 11754601 DOI: 10.1021/Np010212P  0.39
2001 Gu JQ, Park EJ, Luyengi L, Hawthorne ME, Mehta RG, Farnsworth NR, Pezzuto JM, Kinghorn AD. Constituents of Eugenia sandwicensis with potential cancer chemopreventive activity Phytochemistry. 58: 121-127. PMID 11524121 DOI: 10.1016/S0031-9422(01)00180-7  0.306
2001 Mehta RG, Bhat KP, Hawthorne ME, Kopelovich L, Mehta RR, Christov K, Kelloff GJ, Steele VE, Pezzuto JM. Induction of atypical ductal hyperplasia in mouse mammary gland organ culture. Journal of the National Cancer Institute. 93: 1103-6. PMID 11459872 DOI: 10.1093/Jnci/93.14.1103  0.373
2001 Salti GI, Kichina JV, Das Gupta TK, Uddin S, Bratescu L, Pezzuto JM, Mehta RG, Constantinou AI. Betulinic acid reduces ultraviolet-C-induced DNA breakage in congenital melanocytic naeval cells: evidence for a potential role as a chemopreventive agent. Melanoma Research. 11: 99-104. PMID 11333133 DOI: 10.1097/00008390-200104000-00003  0.338
2000 Mehta R, Hawthorne M, Uselding L, Albinescu D, Moriarty R, Christov K. Prevention of N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats by 1α-hydroxyvitamin D5 Journal of the National Cancer Institute. 92: 1836-1840. PMID 11078761 DOI: 10.1093/Jnci/92.22.1836  0.356
2000 Mehta RG. Experimental basis for the prevention of breast cancer. European Journal of Cancer. 36: 1275-1282. PMID 10882866 DOI: 10.1016/S0959-8049(00)00100-3  0.421
2000 Christov K, Shilkaitis A, Green A, Mehta RG, Grubbs C, Kelloff G, Lubet R. Cellular responses of mammary carcinomas to aromatase inhibitors: effects of vorozole. Breast Cancer Research and Treatment. 60: 117-128. PMID 10845274 DOI: 10.1023/A:1006384026252  0.413
2000 Lazzaro G, Agadir A, Qing W, Poria M, Mehta RR, Moriarty RM, Das Gupta TK, Zhang XK, Mehta RG. Induction of differentiation by 1alpha-hydroxyvitamin D(5) in T47D human breast cancer cells and its interaction with vitamin D receptors. European Journal of Cancer (Oxford, England : 1990). 36: 780-6. PMID 10762752 DOI: 10.1016/S0959-8049(00)00016-2  0.406
2000 Mehta RG, Williamson E, Patel MK, Koeffler HP. A Ligand of Peroxisome Proliferator-Activated Receptor γ, Retinoids, and Prevention of Preneoplastic Mammary Lesions Journal of the National Cancer Institute. 92: 418-423. PMID 10699072 DOI: 10.1093/Jnci/92.5.418  0.392
2000 Steele VE, Kelloff GJ, Balentine D, Boone CW, Mehta R, Bagheri D, Sigman CC, Zhu S, Sharma S. Comparative chemopreventive mechanisms of green tea, black tea and selected polyphenol extracts measured by in vitro bioassays. Carcinogenesis. 21: 63-7. PMID 10607735 DOI: 10.1093/Carcin/21.1.63  0.363
2000 Mehta RR, Bratescu L, Graves JM, Green A, Mehta RG. Differentiation of human breast carcinoma cells by a novel vitamin D analog: 1alpha-hydroxyvitamin D5. International Journal of Oncology. 16: 65-138. PMID 10601550 DOI: 10.3892/Ijo.16.1.65  0.42
1999 Mehta R, Gupta A, Dewan S, Chellani H. Hodgkin's disease presenting with bone involvement. Indian Pediatrics. 36: 925-7. PMID 10744874  0.449
1999 Chung HS, Chang LC, Lee SK, Shamon LA, Van Breemen RB, Mehta RG, Farnsworth NR, Pezzuto JM, Kinghorn AD. Flavonoid constituents of Chorizanthe diffusa with potential cancer chemopreventive activity Journal of Agricultural and Food Chemistry. 47: 36-41. PMID 10563845 DOI: 10.1021/Jf980784O  0.354
1999 Agadir A, Lazzaro G, Zheng Y, Zhang X, Mehta R. Resistance of HBL100 human breast epithelial cells to vitamin D action Carcinogenesis. 20: 577-582. PMID 10223184 DOI: 10.1093/Carcin/20.4.577  0.468
1999 Lee SK, Luyengi L, Gerhäuser C, Mar W, Lee K, Mehta RG, Kinghorn AD, Pezzuto JM. Inhibitory effect of munetone, an isoflavonoid, on 12-O-tetradecanoylphorbol 13-acetate-induced ornithine decarboxylase activity. Cancer Letters. 136: 59-65. PMID 10211940 DOI: 10.1016/S0304-3835(98)00309-7  0.379
1999 Jinno H, Steiner MG, Mehta RG, Osborne MP, Telang NT. Inhibition of aberrant proliferation and induction of apoptosis in HER-2/neu oncogene transformed human mammary epithelial cells by N-(4-hydroxyphenyl)retinamide Carcinogenesis. 20: 229-236. PMID 10069458 DOI: 10.1093/Carcin/20.2.229  0.428
1998 Mehta RR, Hawthorne ME, Graves JM, Mehta RG. Metabolism of N-[4-hydroxyphenyl]retinamide (4-HPR) to N-[4-methoxyphenyl]retinamide (4-MPR) may serve as a biomarker for its efficacy against human breast cancer and melanoma cells European Journal of Cancer. 34: 902-907. PMID 9797705 DOI: 10.1016/S0959-8049(98)00032-X  0.463
1998 Lee SK, Qing WG, Mar W, Luyengi L, Mehta RG, Kawanishi K, Fong HH, Beecher CW, Kinghorn AD, Pezzuto JM. Angoline and chelerythrine, benzophenanthridine alkaloids that do not inhibit protein kinase C. The Journal of Biological Chemistry. 273: 19829-33. PMID 9677417 DOI: 10.1074/Jbc.273.31.19829  0.32
1998 Ito A, Shamon LA, Yu B, Mata-Greenwood E, Lee SK, Van Breemen RB, Mehta RG, Farnsworth NR, Fong HHS, Pezzuto JM, Kinghorn AD. Antimutagenic Constituents of Casimiroa edulis with Potential Cancer Chemopreventive Activity Journal of Agricultural and Food Chemistry. 46: 3509-3516. DOI: 10.1021/Jf9802373  0.318
1997 Lazzaro G, Mehta R, Shilkaitis A, DasGupta T. Transformation of human breast epithelial cells by 7, 12, dimethylbenz(a)anthracene, but not by N-methyl-N-nitrosourea, is accompanied by up-regulation of basic fibroblast growth factor. Oncology Reports. 4: 1175-1180. PMID 21590217 DOI: 10.3892/Or.4.6.1175  0.379
1997 Lazzaro G, Sharpless S, Qing W, Mehta R, DasGupta T. Study of nm23 gene expression in an N-methyl-N-nitrosourea transformed human breast epithelial cell line. International Journal of Oncology. 11: 765-769. PMID 21528272 DOI: 10.3892/Ijo.11.4.765  0.371
1997 Mehta RG, Moriarty RM, Mehta RR, Penmasta R, Lazzaro G, Constantinou A, Guo L. Prevention of preneoplastic mammary lesion development by a novel vitamin D analogue, 1alpha-hydroxyvitamin D5. Journal of the National Cancer Institute. 89: 212-8. PMID 9017001 DOI: 10.1093/Jnci/89.3.212  0.376
1997 Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science (New York, N.Y.). 275: 218-20. PMID 8985016 DOI: 10.1126/Science.275.5297.218  0.413
1997 Sharpless SM, Lazzaro G, Marler K, Gupta TKD, Mehta RG. Retinoid-induced apoptosis in human metastatic melanoma cells: a possible treatment role? Melanoma Research. 7. DOI: 10.1097/00008390-199706001-00140  0.322
1996 Steele VE, Sharma S, Mehta R, Elmore E, Redpath L, Rudd C, Bagheri D, Sigman CC, Kelloff GJ. Use of in vitro assays to predict the efficacy of chemopreventive agents in whole animals. Journal of Cellular Biochemistry. Supplement. 26: 29-53. PMID 9154167 DOI: 10.1002/Jcb.240630704  0.382
1995 Mehta RG, Liu J, Constantinou A, Thomas CF, Hawthorne M, You M, Gerhüser C, Pezzuto JM, Moon RC, Moriarty RM. Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage. Carcinogenesis. 16: 399-404. PMID 7859373 DOI: 10.1093/Carcin/16.2.399  0.39
1995 Gerhäuser C, Mar W, Lee SK, Suh N, Luo Y, Kosmeder J, Luyengi L, Fong HHS, KingHorn AD, Moriarty RM, Mehta RG, Constantinou A, Moon RC, Pezzuto JM. Rotenoids mediate potent cancer chemopreventive activity through transcriptional regulation of ornithine decarboxylase. Nature Medicine. 1: 260-266. PMID 7585044 DOI: 10.1038/Nm0395-260  0.368
1991 Mehta RG, Moon RC, Hawthorne M, Formelli F, Costa A. Distribution of fenretinide in the mammary gland of breast cancer patients European Journal of Cancer and Clinical Oncology. 27: 138-141. PMID 1827276 DOI: 10.1016/0277-5379(91)90471-O  0.396
1990 Moon RC, Mehta RG. Chemoprevention of Mammary Cancer by Retinoids Basic Life Sciences. 52: 213-224. PMID 2109594 DOI: 10.1007/978-1-4615-9561-8_18  0.401
1990 Moon RC, Mehta RG. Cancer chemoprevention by retinoids: animal models. Methods in Enzymology. 190: 395-406. PMID 2087191 DOI: 10.1016/0076-6879(90)90045-3  0.408
1989 Moon RC, Mehta RG. Chemoprevention of experimental carcinogenesis in animals. Preventive Medicine. 18: 576-591. PMID 2694156 DOI: 10.1016/0091-7435(89)90031-5  0.412
1989 Moon RC, Pritchard JF, Mehta RG, Nomides CT, Thomas CF, Dinger NM. Suppression of rat mammary cancer development by N-(4-hydroxy-phenyDretinamide (4-HPR) following surgical removal of first palpable tumor Carcinogenesis. 10: 1645-1649. PMID 2527636 DOI: 10.1093/Carcin/10.9.1645  0.321
1986 Mehta RG, Schiff LJ, Moore SJ, Buckley AM, Dawson MI. Cellular retinoic acid-binding protein and its relationship to the biological activity of four synthetic retinoids in hamster tracheal organ culture. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 22: 164-8. PMID 2419303 DOI: 10.1007/Bf02623504  0.301
1985 Kute TE, Linville C, Mehta RG, Moon RC. Cell kinetics in normal and neoplastic mammary tissues by flow cytometric analyses Cytometry. 6: 362-367. PMID 4017801 DOI: 10.1002/Cyto.990060414  0.405
1985 Mehta RG, Moon RC. Role of hormones on the induction of retinoic acid binding protein in mouse mammary gland organ culture Carcinogenesis. 6: 1103-1107. PMID 2990755 DOI: 10.1093/Carcin/6.8.1103  0.36
1984 Dowlatshahi K, Mehta RG, Levin B, Cerny WL, Skinner DB, Moon RC. Retinoic-acid-binding protein in normal and neoplastic human esophagus. Cancer. 54: 308-311. PMID 6327007 DOI: 10.1002/1097-0142(19840715)54:2<308::Aid-Cncr2820540221>3.0.Co;2-4  0.393
1983 Mehta RG, Cerny WL, Moon RC. Retinoids inhibit prolactin-induced development of the mammary gland in vitro Carcinogenesis. 4: 23-26. PMID 6821885 DOI: 10.1093/Carcin/4.1.23  0.358
1982 Moon RC, Mehta RG. Retinoid Binding in Normal and Neoplastic Mammary Tissue Advances in Experimental Medicine and Biology. 138: 231-249. PMID 7200717 DOI: 10.1007/978-1-4615-7192-6_14  0.318
1982 Mehta RG, Kute TE, Hopkins M, Moon RC. Retinoic acid binding proteins and steroid receptor levels in human breast cancer European Journal of Cancer and Clinical Oncology. 18: 221-226. PMID 6284515 DOI: 10.1016/0277-5379(82)90040-2  0.387
1982 Mehta RG, McCormick DL, Cerny WL, Moon RC. Correlation between retinoid inhibition of N-methyl-N-nitrosourea-induced mammary carcinogenesis and levels of retinoic acid binding proteins Carcinogenesis. 3: 89-91. PMID 6279325 DOI: 10.1093/Carcin/3.1.89  0.359
1980 Mehta RG, Fricks CM, Moon RC. Androgen receptors in chemically‐induced colon carcinogenesis Cancer. 45: 1085-1089. PMID 7357503 DOI: 10.1002/1097-0142(19800315)45:5+<1085::Aid-Cncr2820451309>3.0.Co;2-M  0.306
1975 Mehta RG, Banerjee MR. Action of growth-promoting hormones on macromolecular biosynthesis during lobulo-alveolar development of the entire mammary gland in organ culture. Acta Endocrinologica. 80: 501-16. PMID 1242565 DOI: 10.1530/Acta.0.0800501  0.599
1974 Mehta RG, Washburn LL, Young PN, Banerjee MR, Bern HA. Proliferation of preneoplastic mammary nodule outgrowth in mammary fat pads of BALB-c mice in organ culture. Journal of the National Cancer Institute. 52: 1013-7. PMID 4826552 DOI: 10.1093/Jnci/52.3.1013  0.593
1973 Banerjee MR, Mehta RG, Wagner JE. DNA polymerase activity and DNA synthesis in preneoplastic nodule outgrowths of BALB/c and C3H mouse mammary gland Journal of the National Cancer Institute. 50: 339-345. PMID 4349763 DOI: 10.1093/Jnci/50.2.339  0.566
1973 Banerjee DN, Banerjee MR, Mehta RG. Hormonal regulation of rapidly labeled rna in normal preneoplastic and neoplastic tissues of mouse mammary gland Journal of the National Cancer Institute. 51: 843-849. PMID 4200597 DOI: 10.1093/Jnci/51.3.843  0.569
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