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Robert M. Friedlander, MD. MA - Publications

Affiliations: 
Cerebrovascular Neurosurgery  University of Pittsburgh, Pittsburgh, PA, United States 
Website:
http://www.neurosurgery.pitt.edu/research/neuroapoptosis/index.html
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Sinha B, Wu Q, Li W, Tu Y, Sirianni AC, Chen Y, Jiang J, Zhang X, Zhou S, Chen W, Reiter RJ, Manning S, Patel NJ, Aziz-Sultan AM, Inder TE, ... Friedlander RM, et al. Protection of melatonin in experimental models of newborn hypoxic-ischemic brain injury through MT1 receptor. Journal of Pineal Research. PMID 28796402 DOI: 10.1111/Jpi.12443  0.305
2015 Kozai TD, Du Z, Gugel ZV, Smith MA, Chase SM, Bodily LM, Caparosa EM, Friedlander RM, Cui XT. Comprehensive chronic laminar single-unit, multi-unit, and local field potential recording performance with planar single shank electrode arrays. Journal of Neuroscience Methods. 242: 15-40. PMID 25542351 DOI: 10.1016/J.Jneumeth.2014.12.010  0.663
2014 Kozai TD, Li X, Bodily LM, Caparosa EM, Zenonos GA, Carlisle DL, Friedlander RM, Cui XT. Effects of caspase-1 knockout on chronic neural recording quality and longevity: insight into cellular and molecular mechanisms of the reactive tissue response. Biomaterials. 35: 9620-34. PMID 25176060 DOI: 10.1016/J.Biomaterials.2014.08.006  0.703
2014 Zhou H, Wang J, Jiang J, Stavrovskaya IG, Li M, Li W, Wu Q, Zhang X, Luo C, Zhou S, Sirianni AC, Sarkar S, Kristal BS, Friedlander RM, Wang X. N-acetyl-serotonin offers neuroprotection through inhibiting mitochondrial death pathways and autophagic activation in experimental models of ischemic injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2967-78. PMID 24553937 DOI: 10.1523/Jneurosci.1948-13.2014  0.328
2013 Zhang Y, Cook A, Kim J, Baranov SV, Jiang J, Smith K, Cormier K, Bennett E, Browser RP, Day AL, Carlisle DL, Ferrante RJ, Wang X, Friedlander RM. Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobiology of Disease. 55: 26-35. PMID 23537713 DOI: 10.1016/J.Nbd.2013.03.008  0.325
2011 Wang X, Sirianni A, Pei Z, Cormier K, Smith K, Jiang J, Zhou S, Wang H, Zhao R, Yano H, Kim JE, Li W, Kristal BS, Ferrante RJ, Friedlander RM. The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14496-507. PMID 21994366 DOI: 10.1523/Jneurosci.3059-11.2011  0.302
2011 Zhang Y, Wang X, Baranov SV, Zhu S, Huang Z, Fellows-Mayle W, Jiang J, Day AL, Kristal BS, Friedlander RM. Dipyrone inhibits neuronal cell death and diminishes hypoxic/ischemic brain injury. Neurosurgery. 69: 942-56. PMID 21552169 DOI: 10.1227/Neu.0B013E318222Afb2  0.322
2010 Yanamadala V, Friedlander RM. Complement in neuroprotection and neurodegeneration. Trends in Molecular Medicine. 16: 69-76. PMID 20116331 DOI: 10.1016/J.Molmed.2009.12.001  0.315
2009 Wang X, Figueroa BE, Stavrovskaya IG, Zhang Y, Sirianni AC, Zhu S, Day AL, Kristal BS, Friedlander RM. Methazolamide and melatonin inhibit mitochondrial cytochrome C release and are neuroprotective in experimental models of ischemic injury. Stroke; a Journal of Cerebral Circulation. 40: 1877-85. PMID 19299628 DOI: 10.1161/Strokeaha.108.540765  0.334
2008 Zhang WH, Wang H, Wang X, Narayanan MV, Stavrovskaya IG, Kristal BS, Friedlander RM. Nortriptyline protects mitochondria and reduces cerebral ischemia/hypoxia injury. Stroke; a Journal of Cerebral Circulation. 39: 455-62. PMID 18174477 DOI: 10.1161/Strokeaha.107.496810  0.31
2007 Wang H, Guan Y, Wang X, Smith K, Cormier K, Zhu S, Stavrovskaya IG, Huo C, Ferrante RJ, Kristal BS, Friedlander RM. Nortriptyline delays disease onset in models of chronic neurodegeneration. The European Journal of Neuroscience. 26: 633-41. PMID 17686041 DOI: 10.1111/J.1460-9568.2007.05663.X  0.314
2006 Zhang Y, Leavitt BR, van Raamsdonk JM, Dragatsis I, Goldowitz D, MacDonald ME, Hayden MR, Friedlander RM. Huntingtin inhibits caspase-3 activation. The Embo Journal. 25: 5896-906. PMID 17124493 DOI: 10.1038/Sj.Emboj.7601445  0.3
2004 Stavrovskaya IG, Narayanan MV, Zhang W, Krasnikov BF, Heemskerk J, Young SS, Blass JP, Brown AM, Beal MF, Friedlander RM, Kristal BS. Clinically approved heterocyclics act on a mitochondrial target and reduce stroke-induced pathology. The Journal of Experimental Medicine. 200: 211-22. PMID 15263028 DOI: 10.1084/Jem.20032053  0.311
2004 Zhu S, Li M, Figueroa BE, Liu A, Stavrovskaya IG, Pasinelli P, Beal MF, Brown RH, Kristal BS, Ferrante RJ, Friedlander RM. Prophylactic creatine administration mediates neuroprotection in cerebral ischemia in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5909-12. PMID 15229238 DOI: 10.1523/Jneurosci.1278-04.2004  0.359
2003 Zhang WH, Wang X, Narayanan M, Zhang Y, Huo C, Reed JC, Friedlander RM. Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death. Proceedings of the National Academy of Sciences of the United States of America. 100: 16012-7. PMID 14663141 DOI: 10.1073/Pnas.2534856100  0.313
2003 Wang X, Zhu S, Drozda M, Zhang W, Stavrovskaya IG, Cattaneo E, Ferrante RJ, Kristal BS, Friedlander RM. Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 10483-7. PMID 12930891 DOI: 10.1073/Pnas.1832501100  0.314
2003 Friedlander RM. Apoptosis and caspases in neurodegenerative diseases. The New England Journal of Medicine. 348: 1365-75. PMID 12672865 DOI: 10.1056/Nejmra022366  0.307
2002 Guégan C, Vila M, Teismann P, Chen C, Onténiente B, Li M, Friedlander RM, Przedborski S, Teissman P. Instrumental activation of bid by caspase-1 in a transgenic mouse model of ALS. Molecular and Cellular Neurosciences. 20: 553-62. PMID 12213439 DOI: 10.1006/Mcne.2002.1136  0.3
2002 Zhu S, Stavrovskaya IG, Drozda M, Kim BY, Ona V, Li M, Sarang S, Liu AS, Hartley DM, Wu DC, Gullans S, Ferrante RJ, Przedborski S, Kristal BS, Friedlander RM. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature. 417: 74-8. PMID 11986668 DOI: 10.1038/417074A  0.301
2001 Sanchez Mejia RO, Friedlander RM. Caspases in Huntington's disease. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 7: 480-9. PMID 11765125 DOI: 10.1177/107385840100700604  0.328
2001 Sanchez Mejia RO, Ona VO, Li M, Friedlander RM. Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction. Neurosurgery. 48: 1393-9; discussion 1. PMID 11383749 DOI: 10.1097/00006123-200106000-00051  0.334
2000 Fankhauser C, Friedlander RM, Gagliardini V. Prevention of nuclear localization of activated caspases correlates with inhibition of apoptosis. Apoptosis : An International Journal On Programmed Cell Death. 5: 117-32. PMID 11232240 DOI: 10.1023/A:1009672411058  0.303
2000 Friedlander RM. Role of caspase 1 in neurologic disease. Archives of Neurology. 57: 1273-6. PMID 10987893 DOI: 10.1001/Archneur.57.9.1273  0.322
2000 Li M, Ona VO, Chen M, Kaul M, Tenneti L, Zhang X, Stieg PE, Lipton SA, Friedlander RM. Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury. Neuroscience. 99: 333-42. PMID 10938439 DOI: 10.1016/S0306-4522(00)00173-1  0.308
2000 Friedlander RM, Ona V, Stieg PE, Li M, Friedlander RM. 735 Minocycline Reduces Post-traumatic Brain Injury by Inhibition of the Caspase-1 Cell Death Cascade Neurosurgery. 47: 509-510. DOI: 10.1097/00006123-200008000-00083  0.307
1999 Fink KB, Andrews LJ, Butler WE, Ona VO, Li M, Bogdanov M, Endres M, Khan SQ, Namura S, Stieg PE, Beal MF, Moskowitz MA, Yuan J, Friedlander RM. Reduction of post-traumatic brain injury and free radical production by inhibition of the caspase-1 cascade. Neuroscience. 94: 1213-8. PMID 10625061 DOI: 10.1016/S0306-4522(99)00345-0  0.31
1999 Farber A, Connors JP, Friedlander RM, Wagner RJ, Powell RJ, Cronenwett JL. A specific inhibitor of apoptosis decreases tissue injury after intestinal ischemia-reperfusion in mice. Journal of Vascular Surgery. 30: 752-60. PMID 10514215 DOI: 10.1016/S0741-5214(99)70115-1  0.31
1999 Ona VO, Li M, Vonsattel JP, Andrews LJ, Khan SQ, Chung WM, Frey AS, Menon AS, Li XJ, Stieg PE, Yuan J, Penney JB, Young AB, Cha JH, Friedlander RM. Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease. Nature. 399: 263-7. PMID 10353249 DOI: 10.1038/20446  0.303
1998 Friedlander RM, Yuan J. ICE, neuronal apoptosis and neurodegeneration. Cell Death and Differentiation. 5: 823-31. PMID 10203693 DOI: 10.1038/Sj.Cdd.4400433  0.306
1997 Hara H, Friedlander RM, Gagliardini V, Ayata C, Fink K, Huang Z, Shimizu-Sasamata M, Yuan J, Moskowitz MA. Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage. Proceedings of the National Academy of Sciences of the United States of America. 94: 2007-12. PMID 9050895 DOI: 10.1073/Pnas.94.5.2007  0.307
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