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Patrick John Fleming - Publications

Affiliations: 
Georgetown University Medical Center, Washington, DC, United States 
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Devlin T, Fleming PJ, Loza N, Fleming KG. Generation of unfolded outer membrane protein ensembles defined by hydrodynamic properties. European Biophysics Journal : Ebj. PMID 36899114 DOI: 10.1007/s00249-023-01639-y  0.678
2023 Fleming PJ, Correia JJ, Fleming KG. Revisiting macromolecular hydration with HullRadSAS. European Biophysics Journal : Ebj. PMID 36602579 DOI: 10.1007/s00249-022-01627-8  0.526
2021 Alford RF, Fleming PJ, Fleming KG, Gray JJ. Protein Structure Prediction and Design in a Biologically Realistic Implicit Membrane. Biophysical Journal. 120: 4635. PMID 34534449 DOI: 10.1016/j.bpj.2021.09.019  0.67
2020 Marx DC, Plummer AM, Faustino AM, Devlin T, Roskopf MA, Leblanc MJ, Lessen HJ, Amann BT, Fleming PJ, Krueger S, Fried SD, Fleming KG. SurA is a cryptically grooved chaperone that expands unfolded outer membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 33093201 DOI: 10.1073/pnas.2008175117  0.749
2020 Alford RF, Fleming PJ, Fleming KG, Gray JJ. Protein Structure Prediction and Design in a Biologically Realistic Implicit Membrane. Biophysical Journal. PMID 32224301 DOI: 10.1016/J.Bpj.2020.03.006  0.698
2019 Chum AP, Shoemaker SR, Fleming PJ, Fleming KG. Plasticity and transient binding are key ingredients of the periplasmic chaperone network. Protein Science : a Publication of the Protein Society. PMID 31074917 DOI: 10.1002/Pro.3641  0.613
2019 Alford RF, Fleming P, Fleming KG, Gray JJ. A Thermodynamically-Rigorous, Biologically-Driven Energy Function for Membrane Protein Modeling and Design Biophysical Journal. 116: 58a. DOI: 10.1016/J.Bpj.2018.11.358  0.674
2019 Lessen HJ, Fleming P, Fleming KG, Sodt AJ. Transmembrane Beta-Barrel Proteins Rigidify the Bacterial Outer Membrane Biophysical Journal. 116: 327a. DOI: 10.1016/J.Bpj.2018.11.1774  0.643
2018 Lessen HJ, Fleming PJ, Fleming KG, Sodt AJ. Building Blocks of the Outer Membrane: Calculating a general elastic energy model for β-barrel membrane proteins. Journal of Chemical Theory and Computation. PMID 29979594 DOI: 10.1021/Acs.Jctc.8B00377  0.694
2018 Fleming PJ, Fleming KG. HullRad: Fast Calculations of Folded and Disordered Protein and Nucleic Acid Hydrodynamic Properties. Biophysical Journal. 114: 856-869. PMID 29490246 DOI: 10.1016/J.Bpj.2018.01.002  0.595
2018 Alford RF, Fleming P, Fleming KG, Gray JJ. Fast Implicit Potentials for Accurate Prediction and Design of Membrane Protein Structures Biophysical Journal. 114: 345a. DOI: 10.1016/J.Bpj.2017.11.1923  0.665
2016 Costello SM, Plummer AM, Fleming PJ, Fleming KG. Dynamic periplasmic chaperone reservoir facilitates biogenesis of outer membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 27482090 DOI: 10.1073/Pnas.1601002113  0.688
2016 Fleming PJ, Patel DS, Wu EL, Qi Y, Yeom MS, Sousa MC, Fleming KG, Im W. BamA POTRA Domain Interacts with a Native Lipid Membrane Surface. Biophysical Journal. 110: 2698-709. PMID 27332128 DOI: 10.1016/J.Bpj.2016.05.010  0.685
2016 Zaccai NR, Sandlin CW, Hoopes JT, Curtis JE, Fleming PJ, Fleming KG, Krueger S. Deuterium Labeling Together with Contrast Variation Small-Angle Neutron Scattering Suggests How Skp Captures and Releases Unfolded Outer Membrane Proteins. Methods in Enzymology. 566: 159-210. PMID 26791979 DOI: 10.1016/Bs.Mie.2015.06.041  0.676
2016 Costello SM, Plummer AM, Fleming PJ, Fleming KG. A Computational Model for Membrane Protein Flux across the Bacterial Periplasm Biophysical Journal. 110: 58a. DOI: 10.1016/J.Bpj.2015.11.379  0.68
2015 Zaccai NR, Sandlin CW, Hoopes JT, Curtis JE, Fleming PJ, Fleming KG, Krueger S. Deuterium Labeling Together with Contrast Variation Small-Angle Neutron Scattering Suggests How Skp Captures and Releases Unfolded Outer Membrane Proteins Methods in Enzymology. DOI: 10.1016/bs.mie.2015.06.041  0.622
2014 Wu EL, Fleming PJ, Yeom MS, Widmalm G, Klauda JB, Fleming KG, Im W. E. coli outer membrane and interactions with OmpLA. Biophysical Journal. 106: 2493-502. PMID 24896129 DOI: 10.1016/J.Bpj.2014.04.024  0.668
2014 Wu EL, Fleming PJ, Klauda JB, Fleming KG, Im W. A Molecular Dynamics Simulation Study of Outer Membrane Phospholipase a (OMPLA) Structure and Dynamics in an Asymmetric Lipopolysaccharide Membrane Biophysical Journal. 106: 656a. DOI: 10.1016/J.Bpj.2013.11.3632  0.673
2013 Moon CP, Zaccai NR, Fleming PJ, Gessmann D, Fleming KG. Membrane protein thermodynamic stability may serve as the energy sink for sorting in the periplasm. Proceedings of the National Academy of Sciences of the United States of America. 110: 4285-90. PMID 23440211 DOI: 10.1073/Pnas.1212527110  0.776
2012 Fleming PJ, Freites JA, Moon CP, Tobias DJ, Fleming KG. Outer membrane phospholipase A in phospholipid bilayers: a model system for concerted computational and experimental investigations of amino acid side chain partitioning into lipid bilayers. Biochimica Et Biophysica Acta. 1818: 126-34. PMID 21816133 DOI: 10.1016/J.Bbamem.2011.07.016  0.761
2006 Rose GD, Fleming PJ, Banavar JR, Maritan A. A backbone-based theory of protein folding. Proceedings of the National Academy of Sciences of the United States of America. 103: 16623-33. PMID 17075053 DOI: 10.1073/Pnas.0606843103  0.302
2000 Eilers M, Shekar SC, Shieh T, Smith SO, Fleming PJ. Internal packing of helical membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 97: 5796-801. PMID 10823938 DOI: 10.1073/Pnas.97.11.5796  0.494
1995 Pattabiraman N, Ward KB, Fleming PJ. Occluded molecular surface: Analysis of protein packing Journal of Molecular Recognition. 8: 334-344. PMID 9052974 DOI: 10.1002/Jmr.300080603  0.659
1990 Oyarce AM, Fleming PJ. Deglycosylated membranous and soluble dopamine beta-hydroxylase have identical apparent molecular weights. Journal of Molecular Neuroscience : Mn. 1: 171-5. PMID 2642066 DOI: 10.1007/BF02918903  0.335
1990 Kent UM, Fleming PJ. Cytochrome b561 is fatty acylated and oriented in the chromaffin granule membrane with its carboxyl terminus cytoplasmically exposed. Journal of Biological Chemistry. 265: 16422-16427. DOI: 10.1016/s0021-9258(17)46239-9  0.32
1984 Duong LT, Fleming PJ. The asymmetric orientation of cytochrome b561 in bovine chromaffin granule membranes. Archives of Biochemistry and Biophysics. 228: 332-41. PMID 6364990 DOI: 10.1016/0003-9861(84)90074-2  0.374
1979 Fleming PJ, Koppel DE, Lau AL, Strittmatter P. Intramembrane position of the fluorescent tryptophanyl residue in membrane-bound cytochrome b5. Biochemistry. 18: 5458-64. PMID 518849 DOI: 10.1021/BI00591A031  0.333
1979 Enoch HG, Fleming PJ, Strittmatter P. The binding of cytochrome b5 to phospholipid vesicles and biological membranes. Effect of orientation on intermembrane transfer and digestion by carboxypeptidase Y. Journal of Biological Chemistry. 254: 6483-6488. DOI: 10.1016/s0021-9258(18)50393-8  0.318
1977 Fleming PJ, Hajra AK. 1-Alkyl-sn-glycero-3-phosphate: acyl-CoA acyltransferase in rat brain microsomes. The Journal of Biological Chemistry. 252: 1663-72. PMID 838734  0.522
1973 Fleming PJ, Hajra AK. Biosynthesis and characterization of a phosphatidic acid analog containing beta-hydroxy fatty acid. Biochemical and Biophysical Research Communications. 55: 743-51. PMID 4357430 DOI: 10.1016/0006-291X(73)91207-2  0.569
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