Douglas C. Dean - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Molecular Biology, Cell Biology

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lu Q, Scott PA, Vukmanic EV, Kaplan HJ, Dean DC, Li Q. Yap1 is required for maintenance of adult RPE differentiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32223016 DOI: 10.1096/Fj.201903234R  0.364
2020 Chen F, Liu X, Chen Y, Liu JY, Lu H, Wang W, Lu X, Dean KC, Gao L, Kaplan HJ, Dean DC, Peng X, Liu Y. Sphere-induced reprogramming of RPE cells into dual-potential RPE stem-like cells. Ebiomedicine. 52: 102618. PMID 31982829 DOI: 10.1016/J.Ebiom.2019.102618  0.353
2018 Liu Y, Siles L, Postigo A, Dean DC. Epigenetically Distinct Sister Chromatids and Asymmetric Generation of Tumor Initiating Cells. Cell Cycle (Georgetown, Tex.). PMID 30290712 DOI: 10.1080/15384101.2018.1532254  0.358
2018 Liu Y, Siles L, Lu X, Dean KC, Cuatrecasas M, Postigo A, Dean DC. Mitotic polarization of transcription factors during asymmetric division establishes fate of forming cancer cells. Nature Communications. 9: 2424. PMID 29930325 DOI: 10.1038/S41467-018-04663-1  0.358
2017 Cortés M, Sanchez-Moral L, de Barrios O, Fernández-Aceñero MJ, Martínez-Campanario MC, Esteve-Codina A, Darling DS, Győrffy B, Lawrence T, Dean DC, Postigo A. Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles. The Embo Journal. PMID 29038174 DOI: 10.15252/Embj.201797345  0.314
2017 Chen Y, Lu X, Montoya-Durango DE, Liu YH, Dean KC, Darling DS, Kaplan HJ, Dean DC, Gao L, Liu Y. ZEB1 Regulates Multiple Oncogenic Components Involved in Uveal Melanoma Progression. Scientific Reports. 7: 45. PMID 28246385 DOI: 10.1038/S41598-017-00079-X  0.419
2017 Xu N, Chen Y, Dean KC, Lu X, Liu X, Wang W, Dean DC, Kaplan HJ, Gao L, Dong F, Liu Y. Sphere-Induced Rejuvenation of Swine and Human Müller Glia Is Primarily Caused by Telomere Elongation. Stem Cells (Dayton, Ohio). PMID 28152565 DOI: 10.1002/Stem.2585  0.329
2016 Schreck C, Istvánffy R, Ziegenhain C, Sippenauer T, Ruf F, Henkel L, Gärtner F, Vieth B, Florian MC, Mende N, Taubenberger A, Prendergast Á, Wagner A, Pagel C, Grziwok S, ... ... Dean DC, et al. Niche WNT5A regulates the actin cytoskeleton during regeneration of hematopoietic stem cells. The Journal of Experimental Medicine. PMID 27998927 DOI: 10.1084/Jem.20151414  0.365
2015 Sambandam SA, Kasetti RB, Xue L, Dean DC, Lu Q, Li Q. 14-3-3σ regulates keratinocyte proliferation and differentiation by modulating Yap1 cellular localization. The Journal of Investigative Dermatology. 135: 1621-8. PMID 25668240 DOI: 10.1038/Jid.2015.42  0.323
2014 Zhang P, Wei Y, Wang L, Debeb BG, Yuan Y, Zhang J, Yuan J, Wang M, Chen D, Sun Y, Woodward WA, Liu Y, Dean DC, Liang H, Hu Y, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nature Cell Biology. 16: 864-75. PMID 25086746 DOI: 10.1038/Ncb3013  0.351
2014 Liu Y, Sánchez-Tilló E, Lu X, Huang L, Clem B, Telang S, Jenson AB, Cuatrecasas M, Chesney J, Postigo A, Dean DC. The ZEB1 transcription factor acts in a negative feedback loop with miR200 downstream of Ras and Rb1 to regulate Bmi1 expression. The Journal of Biological Chemistry. 289: 4116-25. PMID 24371144 DOI: 10.1074/Jbc.M113.533505  0.371
2014 Wang W, Zhou L, Lee SJ, Liu Y, Fernandez de Castro J, Emery D, Vukmanic E, Kaplan HJ, Dean DC. Swine cone and rod precursors arise sequentially and display sequential and transient integration and differentiation potential following transplantation. Investigative Ophthalmology & Visual Science. 55: 301-9. PMID 24327609 DOI: 10.1167/Iovs.13-12600  0.302
2014 Reynolds MR, Lane AN, Robertson B, Kemp S, Liu Y, Hill BG, Dean DC, Clem BF. Control of glutamine metabolism by the tumor suppressor Rb Oncogene. 33: 556-566. PMID 23353822 DOI: 10.1038/Onc.2012.635  0.405
2013 Liu Y, Sánchez-Tilló E, Lu X, Clem B, Telang S, Jenson AB, Cuatrecasas M, Chesney J, Postigo A, Dean DC. Rb1 family mutation is sufficient for sarcoma initiation. Nature Communications. 4: 2650. PMID 24150016 DOI: 10.1038/Ncomms3650  0.314
2013 Liu Y, Mukhopadhyay P, Pisano MM, Lu X, Huang L, Lu Q, Dean DC. Repression of Zeb1 and hypoxia cause sequential mesenchymal-to-epithelial transition and induction of aid, Oct4, and Dnmt1, leading to immortalization and multipotential reprogramming of fibroblasts in spheres. Stem Cells (Dayton, Ohio). 31: 1350-62. PMID 23554223 DOI: 10.1002/Stem.1382  0.421
2013 Liu Y, Sánchez-Tilló E, Lu X, Huang L, Clem B, Telang S, Jenson AB, Cuatrecasas M, Chesney J, Postigo A, Dean DC. Sequential inductions of the ZEB1 transcription factor caused by mutation of Rb and then Ras proteins are required for tumor initiation and progression. The Journal of Biological Chemistry. 288: 11572-80. PMID 23443660 DOI: 10.1074/Jbc.M112.434951  0.345
2012 Sánchez-Tilló E, Liu Y, de Barrios O, Siles L, Fanlo L, Cuatrecasas M, Darling DS, Dean DC, Castells A, Postigo A. EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness. Cellular and Molecular Life Sciences : Cmls. 69: 3429-56. PMID 22945800 DOI: 10.1007/S00018-012-1122-2  0.37
2011 Zhou L, Wang W, Liu Y, Fernandez de Castro J, Ezashi T, Telugu BP, Roberts RM, Kaplan HJ, Dean DC. Differentiation of induced pluripotent stem cells of swine into rod photoreceptors and their integration into the retina. Stem Cells (Dayton, Ohio). 29: 972-80. PMID 21491544 DOI: 10.1002/Stem.637  0.336
2010 Liu Y, Xin Y, Ye F, Wang W, Lu Q, Kaplan HJ, Dean DC. Taz-tead1 links cell-cell contact to zeb1 expression, proliferation, and dedifferentiation in retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 51: 3372-8. PMID 20207963 DOI: 10.1167/Iovs.09-4321  0.467
2010 Liu Y, Dean DC. Tumor initiation via loss of cell contact inhibition versus Ras mutation: do all roads lead to EMT? Cell Cycle (Georgetown, Tex.). 9: 897-900. PMID 20160473 DOI: 10.4161/Cc.9.5.10933  0.396
2009 El-Naggar S, Liu Y, Dean DC. Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation. Molecular and Cellular Biology. 29: 5710-7. PMID 19703998 DOI: 10.1128/Mcb.00197-09  0.306
2009 Liu Y, Gao L, Zuba-Surma EK, Peng X, Kucia M, Ratajczak MZ, Wang W, Enzmann V, Enzman V, Kaplan HJ, Dean DC. Identification of small Sca-1(+), Lin(-), CD45(-) multipotential cells in the neonatal murine retina. Experimental Hematology. 37: 1096-107, 1107.e1. PMID 19539690 DOI: 10.1016/J.Exphem.2009.05.014  0.329
2009 Liu Y, Ye F, Li Q, Tamiya S, Darling DS, Kaplan HJ, Dean DC. Zeb1 represses Mitf and regulates pigment synthesis, cell proliferation, and epithelial morphology. Investigative Ophthalmology & Visual Science. 50: 5080-8. PMID 19515996 DOI: 10.1167/iovs.08-2911  0.301
2009 Liu Y, Clem B, Zuba-Surma EK, El-Naggar S, Telang S, Jenson AB, Wang Y, Shao H, Ratajczak MZ, Chesney J, Dean DC. Mouse fibroblasts lacking RB1 function form spheres and undergo reprogramming to a cancer stem cell phenotype. Cell Stem Cell. 4: 336-47. PMID 19341623 DOI: 10.1016/J.Stem.2009.02.015  0.404
2008 Liu Y, Peng X, Tan J, Darling DS, Kaplan HJ, Dean DC. Zeb1 mutant mice as a model of posterior corneal dystrophy. Investigative Ophthalmology & Visual Science. 49: 1843-9. PMID 18436818 DOI: 10.1167/Iovs.07-0789  0.331
2008 Liu Y, El-Naggar S, Clem B, Chesney J, Dean DC. The Rb/E2F pathway and Ras activation regulate RecQ helicase gene expression. The Biochemical Journal. 412: 299-306. PMID 18215118 DOI: 10.1042/Bj20070975  0.353
2008 Liu Y, El-Naggar S, Darling DS, Higashi Y, Dean DC. Zeb1 links epithelial-mesenchymal transition and cellular senescence. Development (Cambridge, England). 135: 579-88. PMID 18192284 DOI: 10.1242/Dev.007047  0.414
2007 Liu Y, Costantino ME, Montoya-Durango D, Higashi Y, Darling DS, Dean DC. The zinc finger transcription factor ZFHX1A is linked to cell proliferation by Rb-E2F1. The Biochemical Journal. 408: 79-85. PMID 17655524 DOI: 10.1042/Bj20070344  0.473
2005 Gonzalo S, García-Cao M, Fraga MF, Schotta G, Peters AH, Cotter SE, Eguía R, Dean DC, Esteller M, Jenuwein T, Blasco MA. Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin. Nature Cell Biology. 7: 420-8. PMID 15750587 DOI: 10.1038/Ncb1235  0.309
2002 García-Cao M, Gonzalo S, Dean D, Blasco MA. A role for the Rb family of proteins in controlling telomere length. Nature Genetics. 32: 415-9. PMID 12379853 DOI: 10.1038/Ng1011  0.35
2001 Dahiya A, Wong S, Gonzalo S, Gavin M, Dean DC. Linking the Rb and Polycomb pathways Molecular Cell. 8: 557-568. PMID 11583618 DOI: 10.1016/S1097-2765(01)00346-X  0.708
2001 Zhang HS, Dean DC. Rb-mediated chromatin structure regulation and transcriptional repression. Oncogene. 20: 3134-8. PMID 11420730 DOI: 10.1038/Sj.Onc.1204338  0.352
2001 Yu JT, Foster RG, Dean DC. Transcriptional repression by RB-E2F and regulation of anchorage-independent survival. Molecular and Cellular Biology. 21: 3325-35. PMID 11313458 DOI: 10.1128/Mcb.21.10.3325-3335.2001  0.405
2001 Gavin M, Zhang S, Dahiya A, Luo R, Postigo A, Ma D, Harbour JW, Dean D. Control of exit from G1 and S phases of the cell cycle by histone deacetylase–Rb-hSWI/SNF and Rb-hSWI/SNF repressor complexes Nature Genetics. 27: 55-55. DOI: 10.1038/87088  0.695
2000 Harbour JW, Dean DC. Chromatin remodeling and Rb activity. Current Opinion in Cell Biology. 12: 685-9. PMID 11063932 DOI: 10.1016/S0955-0674(00)00152-6  0.457
2000 Harbour JW, Dean DC. The Rb/E2F pathway: Expanding roles and emerging paradigms Genes and Development. 14: 2393-2409. PMID 11018009 DOI: 10.1101/Gad.813200  0.311
2000 Dahiya A, Gavin MR, Luo RX, Dean DC. Role of the LXCXE binding site in Rb function. Molecular and Cellular Biology. 20: 6799-805. PMID 10958676 DOI: 10.1128/Mcb.20.18.6799-6805.2000  0.691
2000 Postigo AA, Dean DC. Differential expression and function of members of the zfh-1 family of zinc finger/homeodomain repressors. Proceedings of the National Academy of Sciences of the United States of America. 97: 6391-6. PMID 10841546 DOI: 10.1073/Pnas.97.12.6391  0.404
2000 Harbour JW, Dean DC. Rb function in cell-cycle regulation and apoptosis Nature Cell Biology. 2: E65-E67. PMID 10783254 DOI: 10.1038/35008695  0.465
2000 Zhang HS, Gavin M, Dahiya A, Postigo AA, Ma D, Luo RX, Harbour JW, Dean DC. Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell. 101: 79-89. PMID 10778858 DOI: 10.1016/S0092-8674(00)80625-X  0.714
2000 Postigo AA, Dean DC. Independent repressor domains in ZEB regulate muscle and T-cell differentiation. Molecular and Cellular Biology. 19: 7961-71. PMID 10567522 DOI: 10.1128/Mcb.19.12.7961  0.373
1999 Harbour JW, Luo RX, Dei Santi A, Postigo AA, Dean DC. Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1 Cell. 98: 859-869. PMID 10499802 DOI: 10.1016/S0092-8674(00)81519-6  0.368
1999 Postigo AA, Ward E, Skeath JB, Dean DC. zfh-1, the Drosophila homologue of ZEB, is a transcriptional repressor that regulates somatic myogenesis. Molecular and Cellular Biology. 19: 7255-63. PMID 10490660 DOI: 10.1128/Mcb.19.10.7255  0.417
1999 Luo RX, Dean DC. Chromatin remodeling and transcriptional regulation. Journal of the National Cancer Institute. 91: 1288-94. PMID 10433617 DOI: 10.1093/Jnci/91.15.1288  0.361
1999 Postigo AA, Dean DC. ZEB represses transcription through interaction with the corepressor CtBP. Proceedings of the National Academy of Sciences of the United States of America. 96: 6683-8. PMID 10359772 DOI: 10.1073/Pnas.96.12.6683  0.363
1999 Zhang HS, Postigo AA, Dean DC. Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition. Cell. 97: 53-61. PMID 10199402 DOI: 10.1016/S0092-8674(00)80714-X  0.476
1998 Luo RX, Postigo AA, Dean DC. Rb interacts with histone deacetylase to repress transcription. Cell. 92: 463-73. PMID 9491888 DOI: 10.1016/S0092-8674(00)80940-X  0.404
1998 Jesse TL, LaChance R, Iademarco MF, Dean DC. Interferon regulatory factor-2 is a transcriptional activator in muscle where It regulates expression of vascular cell adhesion molecule-1. The Journal of Cell Biology. 140: 1265-76. PMID 9490737 DOI: 10.1083/Jcb.140.5.1265  0.383
1997 Postigo AA, Dean DC. ZEB, a vertebrate homolog of Drosophila Zfh-1, is a negative regulator of muscle differentiation. The Embo Journal. 16: 3935-43. PMID 9233803 DOI: 10.1093/Emboj/16.13.3935  0.373
1997 Postigo AA, Sheppard AM, Mucenski ML, Dean DC. c-Myb and Ets proteins synergize to overcome transcriptional repression by ZEB. The Embo Journal. 16: 3924-34. PMID 9233802 DOI: 10.1093/Emboj/16.13.3924  0.391
1997 Day ML, Foster RG, Day KC, Zhao X, Humphrey P, Swanson P, Postigo AA, Zhang SH, Dean DC. Cell anchorage regulates apoptosis through the retinoblastoma tumor suppressor/E2F pathway. The Journal of Biological Chemistry. 272: 8125-8. PMID 9079623 DOI: 10.1074/Jbc.272.13.8125  0.375
1997 Chow KN, Starostik P, Dean DC. The Rb family contains a conserved cyclin-dependent-kinase-regulated transcriptional repressor motif. Molecular and Cellular Biology. 16: 7173-81. PMID 8943373 DOI: 10.1128/Mcb.16.12.7173  0.422
1996 Chow KN, Dean DC. Domains A and B in the Rb pocket interact to form a transcriptional repressor motif. Molecular and Cellular Biology. 16: 4862-8. PMID 8756645 DOI: 10.1128/Mcb.16.9.4862  0.405
1996 Starostik P, Chow KN, Dean DC. Transcriptional repression and growth suppression by the p107 pocket protein. Molecular and Cellular Biology. 16: 3606-14. PMID 8668177 DOI: 10.1128/Mcb.16.7.3606  0.379
1995 Weintraub SJ, Chow KN, Luo RX, Zhang SH, He S, Dean DC. Mechanism of active transcriptional repression by the retinoblastoma protein. Nature. 375: 812-5. PMID 7596417 DOI: 10.1038/375812A0  0.42
1995 Sheppard AM, McQuillan JJ, Iademarco MF, Dean DC. Control of vascular cell adhesion molecule-1 gene promoter activity during neural differentiation Journal of Biological Chemistry. 270: 3710-3719. PMID 7533155 DOI: 10.1074/Jbc.270.8.3710  0.397
1994 Sheppard AM, Onken MD, Rosen GD, Noakes PG, Dean DC. Expanding roles for alpha 4 integrin and its ligands in development. Cell Adhesion and Communication. 2: 27-43. PMID 7526952 DOI: 10.3109/15419069409014200  0.622
1993 Iademarco MF, Mcquillan JJ, Dean DC. Vascular cell adhesion molecule 1: Contrasting transcriptional control mechanisms in muscle and endothelium Proceedings of the National Academy of Sciences of the United States of America. 90: 3943-3947. PMID 7683412 DOI: 10.1073/Pnas.90.9.3943  0.399
1993 Dean DC, Iademarco MF, Rosen GD, Sheppard AM. The integrin alpha 4 beta 1 and its counter receptor VCAM-1 in development and immune function. The American Review of Respiratory Disease. 148: S43-6. PMID 7504895 DOI: 10.1164/Ajrccm/148.6_Pt_2.S43  0.367
1992 Weintraub SJ, Dean DC. Interaction of a common factor with ATF, Sp1, or TATAA promoter elements is required for these sequences to mediate transactivation by the adenoviral oncogene E1a. Molecular and Cellular Biology. 12: 512-7. PMID 1531085 DOI: 10.1128/Mcb.12.2.512  0.322
1992 Weintraub SJ, Prater CA, Dean DC. Retinoblastoma protein switches the E2F site from positive to negative element. Nature. 358: 259-61. PMID 1321348 DOI: 10.1038/358259A0  0.444
1991 Dean DC, Birkenmeier TM, Rosen GD, Weintraub SJ. Glycoprotein synthesis and secretion. Expression of fibronectin and its cell surface receptors. The American Review of Respiratory Disease. 144: S25-8. PMID 1832529 DOI: 10.1164/Ajrccm/144.3_Pt_2.S25  0.388
1989 Dean DC. Expression of the fibronectin gene American Journal of Respiratory Cell and Molecular Biology. 1: 5-10. PMID 2696510 DOI: 10.1165/Ajrcmb/1.1.5  0.335
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