| Year |
Citation |
Score |
| 2023 |
Anwar T, Sinnett-Smith J, Jin YP, Reed EF, Rozengurt E. Lipophilic Statins Inhibit YAP Nuclear Localization, Coactivator Activity, and Migration in Response to Ligation of HLA Class I Molecules in Endothelial Cells: Role of YAP Multisite Phosphorylation. Journal of Immunology (Baltimore, Md. : 1950). PMID 36881871 DOI: 10.4049/jimmunol.2200568 |
0.306 |
|
| 2023 |
Sinnett-Smith J, Torres-Marquez ME, Chang JK, Shimizu Y, Hao F, Martin MG, Rozengurt E. Statins inhibit protein kinase D (PKD) activation in intestinal cells and prevent PKD1-induced growth of murine enteroids. American Journal of Physiology. Cell Physiology. PMID 36779664 DOI: 10.1152/ajpcell.00286.2022 |
0.452 |
|
| 2022 |
Sinnet-Smith J, Anwar T, Reed EF, Teper Y, Eibl G, Rozengurt E. Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy. Molecular Cancer Therapeutics. PMID 35999654 DOI: 10.1158/1535-7163.MCT-21-0964 |
0.435 |
|
| 2020 |
Anwar T, Sinnett-Smith J, Jin YP, Reed EF, Rozengurt E. Ligation of HLA Class I Molecules Induces YAP Activation through Src in Human Endothelial Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 32848033 DOI: 10.4049/Jimmunol.2000535 |
0.414 |
|
| 2020 |
Amable G, Martínez-León E, Picco ME, Nemirovsky SI, Rozengurt E, Rey O. Metformin inhibition of colorectal cancer cell migration is associated with rebuilt adherens junctions and FAK downregulation. Journal of Cellular Physiology. PMID 32239671 DOI: 10.1002/Jcp.29677 |
0.397 |
|
| 2020 |
Shimizu Y, Sinnett-Smith J, Michelle T, Martin MG, Rozengurt E. Protein kinase D1 (PKD1) signaling induces growth-promoting effects in murine enteroids. Cellular and Molecular Gastroenterology and Hepatology. PMID 32234448 DOI: 10.1016/J.Jcmgh.2020.03.005 |
0.463 |
|
| 2019 |
Hao F, Xu Q, Wang J, Yu S, Chang HH, Sinnett-Smith J, Eibl G, Rozengurt E. Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in KrasG12D mice. Plos One. 14: e0216603. PMID 31100067 DOI: 10.1371/Journal.Pone.0216603 |
0.458 |
|
| 2019 |
Amable G, Martínez-León E, Picco ME, Di Siervi N, Davio C, Rozengurt E, Rey O. Metformin INHIBITS β-Catenin PHOSPHORYLATION ON SER-552 through an AMPK/PI3K/AKT Pathway in colorectal cancer cells. The International Journal of Biochemistry & Cell Biology. PMID 31082618 DOI: 10.1016/J.Biocel.2019.05.004 |
0.395 |
|
| 2019 |
Rozengurt E, Eibl G. Central role of Yes-associated protein and WW-domain-containing transcriptional co-activator with PDZ-binding motif in pancreatic cancer development. World Journal of Gastroenterology. 25: 1797-1816. PMID 31057295 DOI: 10.3748/Wjg.V25.I15.1797 |
0.358 |
|
| 2019 |
León EM, Amable G, Jácamo R, Picco ME, Anaya L, Rozengurt E, Rey O. Protein kinase D1 inhibition interferes with mitosis progression. Journal of Cellular Physiology. PMID 30997696 DOI: 10.1002/Jcp.28651 |
0.467 |
|
| 2019 |
Yu S, Wang J, Sinnett-Smith J, Rozengurt E. Mo1387 – Statins Inhibit Yap Activation in Response to Crosstalk Between Insulin/Igf-1 Receptor and G Protein-Coupled Receptor Signaling Pathways in Pancreatic Ductal Adenocarcinoma Cancer Cells Gastroenterology. 156: S-760. DOI: 10.1016/S0016-5085(19)38839-0 |
0.421 |
|
| 2019 |
Sinnett-Smith J, Chang J, Shimizu Y, Rozengurt E. Su1016 – Protein Kinase D Regulates the Nuclear Import of Erk in Intestinal Epithelial Cells Gastroenterology. 156: S-486. DOI: 10.1016/S0016-5085(19)38075-8 |
0.47 |
|
| 2019 |
Hao F, Xu Q, Wang J, Yu S, Chang H, Sinnett-Smith J, Eibl G, Rozengurt E. Sa2010 – Lipophilic Statins Inhibit Yap Nuclear Localization, Coactivator Activity and Colony Formation in Pancreatic Cancer Cells and Prevent the Initial Stages of Pancreatic Ductal Adenocarcinoma in Kras Mice Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)38033-3 |
0.331 |
|
| 2018 |
Rozengurt E, Sinnett-Smith J, Eibl G. Yes-associated protein (YAP) in pancreatic cancer: at the epicenter of a targetable signaling network associated with patient survival. Signal Transduction and Targeted Therapy. 3: 11. PMID 29682330 DOI: 10.1038/S41392-017-0005-2 |
0.353 |
|
| 2018 |
Jin YP, Valenzuela NM, Zhang X, Rozengurt E, Reed EF. HLA Class II-Triggered Signaling Cascades Cause Endothelial Cell Proliferation and Migration: Relevance to Antibody-Mediated Transplant Rejection. Journal of Immunology (Baltimore, Md. : 1950). PMID 29475988 DOI: 10.4049/Jimmunol.1701259 |
0.416 |
|
| 2018 |
Shimizu Y, Sinnett-Smith J, Wang J, Martin MG, Rozengurt E. Tu1260 - Protein Kinase D Promotes Intestinal Stem Cell Proliferation and Enteroid Growth Gastroenterology. 154: S-917-S-918. DOI: 10.1016/S0016-5085(18)33086-5 |
0.439 |
|
| 2018 |
Hao F, Sinnett-Smith J, Rozengurt E. Sa1378 - Role of Pi3K and Pkd in Mediating Yap Activation in Response to Crosstalk Between Insulin/Igf-1 Receptor and G Protein-Coupled Receptor Signaling Pathways in Pancreatic Ductal Adenocarcinoma Cancer Cells Gastroenterology. 154: S-284. DOI: 10.1016/S0016-5085(18)31309-X |
0.422 |
|
| 2018 |
Hao F, Sinnett-Smith J, Rozengurt E. Sa1374 - Statins Potently Inhibit Yap Nuclear Localization, Function and Proliferation of Human and Mouse Pancreatic Ductal Adenocarcinoma Cancer (PDAC) Cells Gastroenterology. 154: S-283. DOI: 10.1016/S0016-5085(18)31305-2 |
0.353 |
|
| 2018 |
Chang J, Sinnett-Smith J, Rozengurt E. 911 - The P21-Activated Kinase (PAK) I and II Phosphorylate PKD1 at a Novel Site and Regulate PKD1 Intracellular Distribution in Intestinal Epithelial Cells Gastroenterology. 154: S-180. DOI: 10.1016/S0016-5085(18)31013-8 |
0.457 |
|
| 2018 |
Li F, Valenzuela N, Sosa R, Rozengurt E, Reed EF. OR2 Ligation of HLA class II molecules promotes endothelial cell permeability through activated Src and ERK signals Human Immunology. 79: 9. DOI: 10.1016/J.Humimm.2018.07.007 |
0.351 |
|
| 2017 |
Salehi S, Sosa RA, Jin YP, Kageyama S, Fishbein MC, Rozengurt E, Kupiec-Weglinski JW, Reed EF. Outside-in HLA class I signaling regulates ICAM-1 clustering and endothelial-monocyte interactions via mTOR in transplant antibody-mediated rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 29045076 DOI: 10.1111/Ajt.14544 |
0.355 |
|
| 2017 |
Chang JK, Ni Y, Han L, Sinnett-Smith J, Jacamo R, Rey O, Young SH, Rozengurt E. Protein kinase D1 (PKD1) phosphorylation on Ser(203) by type I p21-activated kinase (PAK) regulates PKD1 localization. The Journal of Biological Chemistry. PMID 28408623 DOI: 10.1074/Jbc.M116.771394 |
0.508 |
|
| 2017 |
Hao F, Xu Q, Zhao Y, Stevens JV, Young SH, Sinnett-Smith J, Rozengurt E. Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells. Molecular Cancer Research : McR. PMID 28360038 DOI: 10.1158/1541-7786.Mcr-17-0023 |
0.462 |
|
| 2017 |
Schmidt A, Sinnett-Smith J, Young S, Chang HH, Hines OJ, Dawson DW, Rozengurt E, Eibl G. Direct growth-inhibitory effects of prostaglandin E2 in pancreatic cancer cells in vitro through an EP4/PKA-mediated mechanism. Surgery. PMID 28222855 DOI: 10.1016/J.Surg.2016.12.037 |
0.363 |
|
| 2017 |
Chang J, Sinnett-Smith J, Jacamo R, Young SH, Rey O, Rozengurt E. P21-Activated Kinase (PAK)-Mediated Phosphorylation of Protein Kinase D1 (PKD1) Triggers Membrane Dissociation of PKD1 in Intestinal Epithelial Cells: Identification of a Novel Mechanism in the Regulation of PKD1 Localization Gastroenterology. 152: S1037. DOI: 10.1016/S0016-5085(17)33504-7 |
0.489 |
|
| 2017 |
Sinnett-Smith J, Chang J, Rozengurt E. Crosstalk Between Protein Kinase D1 (PKD1) and P21-Activated Kinase (PAK) in Intestinal Epithelial Cells: Identification of a Novel Phosphorylation Site within the N-Terminal Region of PKD1 Gastroenterology. 152: S1036-S1037. DOI: 10.1016/S0016-5085(17)33501-1 |
0.469 |
|
| 2017 |
Hao F, Xu Q, Zhao Y, Sinnett-Smith J, Young SH, Stevens JV, Rozengurt E. Statins Potently Inhibit YAP Function and Proliferation of Pancreatic Ductal Adenocarcinoma Cancer (PDAC) Cells Gastroenterology. 152: S837-S838. DOI: 10.1016/S0016-5085(17)32892-5 |
0.362 |
|
| 2017 |
Hao F, Chang J, Sinnett-Smith J, Eibl G, Chang H, Rozengurt E. Statins Potently Inhibit YAP Activity and Proliferation of Mouse Pancreatic Cells Isolated From KC and KPC Mice Gastroenterology. 152: S837. DOI: 10.1016/S0016-5085(17)32891-3 |
0.348 |
|
| 2017 |
Xu Q, Hao F, Zhao Y, Sinnett-Smith J, Rozengurt E. Statins Inhibit Proliferation of Pancreatic Ductal Adenocarcinoma Cancer (PDAC) Cells Acting Synergistically with Metformin and Inhibitors of MEK and MTOR Gastroenterology. 152: S837. DOI: 10.1016/S0016-5085(17)32890-1 |
0.396 |
|
| 2017 |
Hao F, Xu Q, Stevens JV, Sinnett-Smith J, Rozengurt E. Crosstalk between INSULIN/IGF-1 Receptor and G Protein-Coupled Receptor (GPCR) Signaling Pathways Stimulates Yap Function in Pancreatic Ductal Adenocarcinoma Cancer (PDAC) Cells Gastroenterology. 152: S802. DOI: 10.1016/S0016-5085(17)32773-7 |
0.403 |
|
| 2017 |
Wang J, Sinnett-Smith J, Rozengurt E. Protein Kinase D (PKD) Mediates Yes-Associated Protein (YAP) Activation in Response to G Protein-Coupled Receptor Activation in Intestinal Epithelial Cells: Identification of a Novel Crosstalk Between PKD and YAP Gastroenterology. 152: S737-S738. DOI: 10.1016/S0016-5085(17)32562-3 |
0.454 |
|
| 2016 |
Wang J, Sinnett-Smith J, Stevens JV, Young SH, Rozengurt E. Biphasic regulation of Yes-associated Protein (YAP) cellular localization, phosphorylation and activity by G protein-coupled receptor agonists in intestinal epithelial cells: a novel role for protein kinase D (PKD). The Journal of Biological Chemistry. PMID 27369082 DOI: 10.1074/Jbc.M115.711275 |
0.55 |
|
| 2016 |
Wang J, Han L, Sinnett-Smith J, Han LL, Stevens JV, Rozengurt N, Young SH, Rozengurt E. Crosstalk between protein kinase D (PKD) and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552. American Journal of Physiology. Cell Physiology. ajpcell.00302.2015. PMID 26739494 DOI: 10.1152/Ajpcell.00302.2015 |
0.426 |
|
| 2016 |
Wang J, Han L, Sinnett-Smith J, Rozengurt E. Sa2047 Regulation of YAP Localization and Phosphorylation in Intestinal Epithelial Cells: Identification of a Novel Crosstalk Between YAP and PKD Signaling Gastroenterology. 150: S439. DOI: 10.1016/S0016-5085(16)31524-4 |
0.433 |
|
| 2016 |
Xu Q, Soares H, Young SH, Sinnett-Smith J, Rozengurt E. Sa1520 Potent Suppression of the Growth of Human Pancreatic Cancer Cells by Combinations of Inhibitors of the PI3K/mTOR and MEK/ERK Pathways Gastroenterology. 150: S330. DOI: 10.1016/S0016-5085(16)31163-5 |
0.437 |
|
| 2016 |
Sinnett-Smith J, Wang J, Rozengurt E. 673 Identification of a Novel Crosstalk Mechanism Between Protein Kinase D1 (PKD1) and p21-Activated Kinase (PAK) in Intestinal Epithelial Cells Gastroenterology. 150: S138. DOI: 10.1016/S0016-5085(16)30564-9 |
0.49 |
|
| 2016 |
Xu Q, Zhao Y, Hao F, Wang J, Sinnett-Smith J, Rozengurt E. 557 Statins Inhibit YAP Function and Potently Restrain the Proliferation of Pancreatic Ductal Adenocarcinoma Cancer Cells Gastroenterology. 150: S118. DOI: 10.1016/S0016-5085(16)30502-9 |
0.364 |
|
| 2016 |
Sinnett-Smith J, Wang J, Rozengurt N, Young SH, Rozengurt E. 99 Positive Crosstalk Between PKD1 and β-Catenin Signaling Pathways in Intestinal Epithelial Cells Gastroenterology. 150: S25. DOI: 10.1016/S0016-5085(16)30210-4 |
0.316 |
|
| 2015 |
Zhou G, Yu J, Wang A, Liu SH, Sinnett-Smith J, Wu J, Sanchez R, Nemunaitis J, Ricordi C, Rozengurt E, Brunicardi FC. Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma. Current Molecular Medicine. PMID 26695692 DOI: 10.2174/1566524016666151222145551 |
0.524 |
|
| 2015 |
Chang HH, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G. Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1. American Journal of Physiology. Cell Physiology. ajpcell.00417.2014. PMID 26310818 DOI: 10.1152/Ajpcell.00417.2014 |
0.435 |
|
| 2015 |
Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2. Molecular Cancer Therapeutics. 14: 1014-23. PMID 25673820 DOI: 10.1158/1535-7163.Mct-14-0669 |
0.515 |
|
| 2015 |
Soares HP, Ming M, Sinnett-Smith J, Mellon M, Rozengurt E. Abstract A109: Dual mTOR/PI3K inhibitors induce compensatory MEK/ERK activation in human pancreatic cancer cells: A mechanism contributing to drug resistance Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A109 |
0.521 |
|
| 2015 |
Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E. Abstract 670: Targeting PI3K/mTOR leads to MEK/ERK over-activation in pancreatic cancer through suppression of mTORC2 Cancer Research. 75: 670-670. DOI: 10.1158/1538-7445.Am2015-670 |
0.502 |
|
| 2015 |
Chang H, Young S, Sinnett-Smith J, Chou CEN, Hines OJ, Rozengurt E, Eibl G. Abstract 1028: Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA and EP1/calcium-mediated mechanisms in human pancreatic carcinoma cells Cancer Research. 75: 1028-1028. DOI: 10.1158/1538-7445.Am2015-1028 |
0.376 |
|
| 2015 |
Ming M, Wang J, Sinnett-Smith J, Young SH, Soares HP, Rozengurt E. Tu1988 Role of AMPK in the Inhibitory Effects of Metformin and Berberine on mTORC1, ERK, DNA Synthesis and Proliferation in Human Pancreatic Cancer Cells Gastroenterology. 148: S-953. DOI: 10.1016/S0016-5085(15)33254-6 |
0.394 |
|
| 2015 |
Soares HP, Ming M, Young SH, Sinnett-Smith J, Rozengurt E. Tu1972 Dual PI3K/mTOR Inhibitors Induce Rapid Over-Activation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells Through Suppression of mTORC2 Gastroenterology. 148. DOI: 10.1016/S0016-5085(15)33239-X |
0.452 |
|
| 2015 |
Wang J, Sinnett-Smith J, Ni Y, Rozengurt E. Mo1885 Role of the Hippo-YAP Pathway in the Regulation of DNA Synthesis by cAMP in Intestinal Epithelial Cells and Swiss 3T3 Fibroblasts Gastroenterology. 148: S-735. DOI: 10.1016/S0016-5085(15)32514-2 |
0.505 |
|
| 2015 |
Wang J, Sinnett-Smith J, Rozengurt E. Mo1884 Regulation of YAP Localization and Phosphorylation in Intestinal Epithelial Cells Gastroenterology. 148: S-735. DOI: 10.1016/S0016-5085(15)32513-0 |
0.499 |
|
| 2015 |
Sinnett-Smith J, Ni Y, Rozengurt E. Mo1882 N-Terminal Phosphorylation of Protein Kinase D1 (PKD1) in Intestinal Epithelial Cells: A New Input in PKD1 Regulation Gastroenterology. 148: S-734. DOI: 10.1016/S0016-5085(15)32511-7 |
0.452 |
|
| 2015 |
Sinnett-Smith J, Ni Y, Rozengurt N, Young SH, Rozengurt E. 252 Crosstalk Between PKD1 and β-Catenin Signaling Pathways in PKD1 Transgenic Mice and Cultures of Intestinal Epithelial Cells Gastroenterology. 148: S-57. DOI: 10.1016/S0016-5085(15)30197-9 |
0.305 |
|
| 2014 |
Ming M, Sinnett-Smith J, Wang J, Soares HP, Young SH, Eibl G, Rozengurt E. Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. Plos One. 9: e114573. PMID 25493642 DOI: 10.1371/Journal.Pone.0114573 |
0.489 |
|
| 2014 |
Rozengurt E, Soares HP, Sinnet-Smith J. Suppression of feedback loops mediated by PI3K/mTOR induces multiple overactivation of compensatory pathways: an unintended consequence leading to drug resistance. Molecular Cancer Therapeutics. 13: 2477-88. PMID 25323681 DOI: 10.1158/1535-7163.Mct-14-0330 |
0.417 |
|
| 2014 |
Rozengurt E. Mechanistic target of rapamycin (mTOR): a point of convergence in the action of insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer cells. Frontiers in Physiology. 5: 357. PMID 25295009 DOI: 10.3389/Fphys.2014.00357 |
0.382 |
|
| 2014 |
Zhou G, Sinnett-Smith J, Liu SH, Yu J, Wu J, Sanchez R, Pandol SJ, Abrol R, Nemunaitis J, Rozengurt E, Brunicardi FC. Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin. Frontiers in Physiology. 5: 226. PMID 25009500 DOI: 10.3389/Fphys.2014.00226 |
0.39 |
|
| 2014 |
Sinnett-Smith J, Ni Y, Wang J, Ming M, Young SH, Rozengurt E. Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling. American Journal of Physiology. Cell Physiology. 306: C961-71. PMID 24647541 DOI: 10.1152/Ajpcell.00048.2014 |
0.504 |
|
| 2014 |
Jin YP, Valenzuela NM, Ziegler ME, Rozengurt E, Reed EF. Everolimus inhibits anti-HLA I antibody-mediated endothelial cell signaling, migration and proliferation more potently than sirolimus. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 806-19. PMID 24580843 DOI: 10.1111/Ajt.12669 |
0.425 |
|
| 2014 |
Young SH, Rey O, Sinnett-Smith J, Rozengurt E. Intracellular Ca2+ oscillations generated via the Ca2+-sensing receptor are mediated by negative feedback by PKCα at Thr888. American Journal of Physiology. Cell Physiology. 306: C298-306. PMID 24336654 DOI: 10.1152/Ajpcell.00194.2013 |
0.303 |
|
| 2014 |
Ni Y, Sinnett-Smith J, Young SH, Rozengurt E. Correction: PKD1 Mediates Negative Feedback of PI3K/Akt Activation in Response to G Protein-Coupled Receptors Plos One. 9. DOI: 10.1371/Annotation/70D3C7B0-9718-4Bb1-Abed-D0Defc3B7Fc4 |
0.428 |
|
| 2014 |
Soares HP, Ming M, Mellon M, Sinnet-Smith J, Rozengurt E. Abstract 5453: Dual mTOR/PI3K inhibitors induce ERK pathway overactivation in pancreatic cell lines: Rationale for combinatory therapy Cancer Research. 74: 5453-5453. DOI: 10.1158/1538-7445.Am2014-5453 |
0.395 |
|
| 2014 |
Ming M, Wang J, Sinnett-Smith J, Young SH, Rozengurt E. Tu1916 Berberine Potently Activates AMPK and Inhibits mTORC1, ERK and Cell Cycle Progression of Human Pancreatic Cancer Cells In Vitro and Reduces the Growth of Human Pancreatic Cancer Xenografts In Vivo Gastroenterology. 146: S-872. DOI: 10.1016/S0016-5085(14)63171-1 |
0.396 |
|
| 2014 |
Soares HP, Ming M, Mellon M, Sinnett-Smith J, Rozengurt E. Tu1915 Suppression of the mTOR/PI3K Pathway Promotes ERK Pathway Activation in Human Pancreatic Cancer Cells Gastroenterology. 146: S-872. DOI: 10.1016/S0016-5085(14)63170-X |
0.529 |
|
| 2014 |
Guha S, Sinnett-Smith J, Rozengurt E. Tu1914 Identification of a Novel Protein Kinase D1 (PKD1)/ RIN1 Axis in Pancreatic Cancer Cells Gastroenterology. 146: S-871. DOI: 10.1016/S0016-5085(14)63169-3 |
0.625 |
|
| 2014 |
Sinnett-Smith J, Ni Y, Ming M, Young SH, Rozengurt E. Tu1212 PKD1-Mediates Class Iia Histone Deacetylase Phosphorylation and Nuclear/Cytoplasmic Shuttling in Intestinal Epithelial Cells Gastroenterology. 146: S-785. DOI: 10.1016/S0016-5085(14)62833-X |
0.38 |
|
| 2014 |
Wang J, Ming M, Ni Y, Sinnett-Smith J, Rozengurt E. Mo1780 Dissociation of GPCR-Stimulated DNA Synthesis From Dephosphorylation of YAP at Ser-127 Gastroenterology. 146: S-658. DOI: 10.1016/S0016-5085(14)62396-9 |
0.335 |
|
| 2014 |
Ni Y, Sinnett-Smith J, Young SH, Soares HP, Rozengurt E. 402 Protein Kinase D1 (PKD1) Regulates the Accumulation of the Second Messenger Phosphatidylinositol (3,4,5)-Trisphosphate in Intestinal Epithelial Cells Gastroenterology. 146: S-86. DOI: 10.1016/S0016-5085(14)60310-3 |
0.477 |
|
| 2014 |
Sinnett-Smith J, Ni Y, Young SH, Rozengurt E. 136 PKD1 Functions Upstream of PKA in a Novel Pathway That Links GPCR Activation to β-Catenin Phosphorylation At Ser552 in Intestinal Epithelial Cells Gastroenterology. 146: S-38. DOI: 10.1016/S0016-5085(14)60131-1 |
0.416 |
|
| 2014 |
Zhou G, Liu S, Yu J, Wu J, Sanchez R, Rozengurt E, Brunicardi F. Caspase-Dependent Down-Regulation Receptor Substrate of Insulin 1 by Protein Phosphatase 4 Journal of Surgical Research. 186: 639. DOI: 10.1016/J.Jss.2013.11.659 |
0.337 |
|
| 2013 |
Ni Y, Sinnett-Smith J, Young SH, Rozengurt E. PKD1 mediates negative feedback of PI3K/Akt activation in response to G protein-coupled receptors. Plos One. 8: e73149. PMID 24039875 DOI: 10.1371/Journal.Pone.0073149 |
0.532 |
|
| 2013 |
Yoo J, Rodriguez Perez CE, Nie W, Sinnett-Smith J, Rozengurt E. TNF-α and LPA promote synergistic expression of COX-2 in human colonic myofibroblasts: role of LPA-mediated transactivation of upregulated EGFR. Bmc Gastroenterology. 13: 90. PMID 23688423 DOI: 10.1186/1471-230X-13-90 |
0.382 |
|
| 2013 |
Soares HP, Ni Y, Kisfalvi K, Sinnett-Smith J, Rozengurt E. Different patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells. Plos One. 8: e57289. PMID 23437362 DOI: 10.1371/Journal.Pone.0057289 |
0.507 |
|
| 2013 |
Giovinazzo F, Malpeli G, Zanini S, Parenti M, Piemonti L, Colombatti M, Valenti MT, Dalle Carbonare L, Scarpa A, Sinnett-Smith J, Rozengurt E, Bassi C, Innamorati G. Ectopic expression of the heterotrimeric G15 protein in pancreatic carcinoma and its potential in cancer signal transduction. Cellular Signalling. 25: 651-9. PMID 23200847 DOI: 10.1016/J.Cellsig.2012.11.018 |
0.42 |
|
| 2013 |
Sinnett-Smith J, Kisfalvi K, Kui R, Rozengurt E. Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK. Biochemical and Biophysical Research Communications. 430: 352-7. PMID 23159620 DOI: 10.1016/J.Bbrc.2012.11.010 |
0.412 |
|
| 2013 |
Soares HP, Yang N, Sinnett-Smith J, Kui R, Rozengurt E. Abstract 4007: Different patterns of Akt and ERK feedback activation in response to allosteric and active-site mTOR inhibitors in comparison to metformin in pancreatic cancer cells. Cancer Research. 73: 4007-4007. DOI: 10.1158/1538-7445.Am2013-4007 |
0.493 |
|
| 2013 |
Sinnett-Smith J, Kisfalvi K, Young SH, Hines OJ, Eibl G, Rozengurt E. Tu1889 The Isoquinoline Alkaloid Berberine Inhibits the Growth of Human Pancreatic Cancer Cells In Vitro and In Vivo Gastroenterology. 144: S-873. DOI: 10.1016/S0016-5085(13)63246-1 |
0.361 |
|
| 2013 |
Ni Y, Sinnett-Smith J, Rozengurt E. Sa1743 Identification of Protein Kinase D1 As a Mediator of Feedback Inhibition of PI3K/AKT Activation in Intestinal Epithelial Cells Stimulated With G Protein-Coupled Receptor Agonists Gastroenterology. 144: S-296. DOI: 10.1016/S0016-5085(13)61055-0 |
0.513 |
|
| 2013 |
Ni Y, Sinnett-Smith J, Young SH, Rozengurt E. Sa1738 Crosstalk Between PKD1 and β-Catenin Signaling Pathways in Intestinal Epithelial Cells Gastroenterology. 144: S-295. DOI: 10.1016/S0016-5085(13)61050-1 |
0.391 |
|
| 2013 |
Young SH, Rey O, Sinnett-Smith J, Rozengurt E. Sa1737 Intracellular CA2+ Oscillations Produced by the CA2+-Sensing Receptor Are Mediated by Negative Feedback by Protein Kinase C At Thr888 Gastroenterology. 144: S-295. DOI: 10.1016/S0016-5085(13)61049-5 |
0.403 |
|
| 2013 |
Young SH, Sinnett-Smith J, Rozengurt E. Sa1736 Protein Kinase D1 (PKD1) Promotes Migration of Intestinal Epithelial Cells Gastroenterology. 144: S-295. DOI: 10.1016/S0016-5085(13)61048-3 |
0.463 |
|
| 2013 |
Sinnett-Smith J, Kui RK, Rozengurt E. Sa1729 Protein Kinase D1 Is an Upstream Kinase for Class II Histone Deacetylases (HDAC) 4, 5 and 7 in Intestinal Epithelial Cells Gastroenterology. 144: S-293. DOI: 10.1016/S0016-5085(13)61041-0 |
0.455 |
|
| 2012 |
Ziegler ME, Jin YP, Young SH, Rozengurt E, Reed EF. HLA class I-mediated stress fiber formation requires ERK1/2 activation in the absence of an increase in intracellular Ca2+ in human aortic endothelial cells. American Journal of Physiology. Cell Physiology. 303: C872-82. PMID 22914643 DOI: 10.1152/Ajpcell.00199.2012 |
0.408 |
|
| 2012 |
Young SH, Rozengurt N, Sinnett-Smith J, Rozengurt E. Rapid protein kinase D1 signaling promotes migration of intestinal epithelial cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G356-66. PMID 22595992 DOI: 10.1152/Ajpgi.00025.2012 |
0.472 |
|
| 2012 |
Yoo J, Rodriguez Perez CE, Nie W, Edwards RA, Sinnett-Smith J, Rozengurt E. TNF-α induces upregulation of EGFR expression and signaling in human colonic myofibroblasts. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G805-14. PMID 22301110 DOI: 10.1152/Ajpgi.00522.2011 |
0.379 |
|
| 2012 |
Waldron RT, Innamorati G, Torres-Marquez ME, Sinnett-Smith J, Rozengurt E. Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq. Cellular Signalling. 24: 914-21. PMID 22227248 DOI: 10.1016/J.Cellsig.2011.12.014 |
0.529 |
|
| 2012 |
Rey O, Chang W, Bikle D, Rozengurt N, Young SH, Rozengurt E. Negative cross-talk between calcium-sensing receptor and β-catenin signaling systems in colonic epithelium. The Journal of Biological Chemistry. 287: 1158-67. PMID 22094462 DOI: 10.1074/Jbc.M111.274589 |
0.387 |
|
| 2012 |
Kisfalvi K, Sinnett-Smith J, Young SH, Eibl G, Rozengurt E. Tu2034 Berberine Inhibits the Growth of Human Pancreatic Cancer Cells In Vitro and In Vivo Gastroenterology. 142: S-907. DOI: 10.1016/S0016-5085(12)63521-5 |
0.362 |
|
| 2012 |
Yoo J, Perez CER, Nie W, Sinnett-Smith J, Rozengurt E. Tu1824 TNF-a Induces Up-Regulation of EGFR Expression and Signaling in Human Colonic Myofibroblasts Gastroenterology. 142: S-855. DOI: 10.1016/S0016-5085(12)63311-3 |
0.352 |
|
| 2012 |
Young SH, Sinnett-Smith J, Rozengurt E. Mo2043 Protein Kinase D1 (Pkd1) Activation is an Early Event in Wounded Monolayers of Intestinal Epithelial Cells Gastroenterology. 142: S-727. DOI: 10.1016/S0016-5085(12)62822-4 |
0.378 |
|
| 2012 |
Sinnett-Smith J, Kui RK, Rozengurt E. Mo1648 Protein Kinase D1 Mediates Mitogenic Signaling in Intestinal Epithelial Cells Gastroenterology. 142: S-649. DOI: 10.1016/S0016-5085(12)62503-7 |
0.489 |
|
| 2012 |
Sinnett-Smith J, Young SH, Rozengurt N, Kui RK, Rey O, Rozengurt E. Mo1644 Protein Kinase D1 (Pkd1) Mediates β-Catenin Signaling and Phosphorylation at Ser552 in Intestinal Epithelial Cells Gastroenterology. 142: S-648. DOI: 10.1016/S0016-5085(12)62499-8 |
0.464 |
|
| 2012 |
Sinnett-Smith J, Young SH, Soares HP, Kui RK, Rozengurt E. 1062 The Direct AMPK Activator a-769662 Inhibits Mitogenic Signaling in Pancreatic Cancer Cells Gastroenterology. 142: S-188. DOI: 10.1016/S0016-5085(12)60705-7 |
0.417 |
|
| 2012 |
Sinnett-Smith J, Kisfalvi K, Kui RK, Young SH, Rozengurt E. 649 Synergistic Inhibition of Pancreatic Cancer Cell Proliferation by Metformin and Rapamycin: Identification of a Novel Combinatorial Drug Strategy Gastroenterology. 142: S-129. DOI: 10.1016/S0016-5085(12)60489-2 |
0.336 |
|
| 2012 |
Sinnett-Smith J, Kui RK, Rozengurt E. 299 Identification of Protein Kinase D1 as an Upstream Kinase of Class II Histone Deacetylases (HDAC) 4 and 7 in Intestinal Epithelial Cells Gastroenterology. 142: S-67. DOI: 10.1016/S0016-5085(12)60260-1 |
0.454 |
|
| 2012 |
Vegezzi G, Sinnett-Smith J, Koon HW, Barocelli E, Pothoulakis C, Rozengurt E, Sternini C. 198 Bitter Stimuli Induce ERK Activation in Mouse and Human Cell Lines Gastroenterology. 142: S-49. DOI: 10.1016/S0016-5085(12)60187-5 |
0.384 |
|
| 2011 |
Yoo J, Rodriguez Perez CE, Nie W, Sinnett-Smith J, Rozengurt E. Protein kinase D1 mediates synergistic MMP-3 expression induced by TNF-α and bradykinin in human colonic myofibroblasts. Biochemical and Biophysical Research Communications. 413: 30-5. PMID 21867693 DOI: 10.1016/J.Bbrc.2011.08.029 |
0.337 |
|
| 2011 |
Rozengurt E. Neurokinin 1 receptor desensitization and resensitization: is it all happening at the membrane? Focus on "Protein phosphatase 2A mediates resensitization of the neurokinin 1 receptor". American Journal of Physiology. Cell Physiology. 301: C772-4. PMID 21832247 DOI: 10.1152/Ajpcell.00274.2011 |
0.307 |
|
| 2011 |
Rozengurt E. Protein kinase D signaling: multiple biological functions in health and disease. Physiology (Bethesda, Md.). 26: 23-33. PMID 21357900 DOI: 10.1152/Physiol.00037.2010 |
0.442 |
|
| 2011 |
Rodriguez Perez CE, Nie W, Sinnett-Smith J, Rozengurt E, Yoo J. TNF-α potentiates lysophosphatidic acid-induced COX-2 expression via PKD in human colonic myofibroblasts. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G637-46. PMID 21292998 DOI: 10.1152/Ajpgi.00381.2010 |
0.422 |
|
| 2011 |
Sinnett-Smith J, Rozengurt N, Kui R, Huang C, Rozengurt E. Protein kinase D1 mediates stimulation of DNA synthesis and proliferation in intestinal epithelial IEC-18 cells and in mouse intestinal crypts. The Journal of Biological Chemistry. 286: 511-20. PMID 21051537 DOI: 10.1074/Jbc.M110.167528 |
0.503 |
|
| 2011 |
Ochi N, Tanasanvimon S, Matsuo Y, Tong Z, Sung B, Aggarwal BB, Sinnett-Smith J, Rozengurt E, Guha S. Protein kinase D1 promotes anchorage-independent growth, invasion, and angiogenesis by human pancreatic cancer cells. Journal of Cellular Physiology. 226: 1074-81. PMID 20857418 DOI: 10.1002/Jcp.22421 |
0.625 |
|
| 2011 |
Sinnett-Smith J, Guha S, Kisfalvi K, Rozengurt E. Protein Kinase D1 Mediates Mitogenic Signaling in Human Pancreatic Carcinoma PANC-1 Cells Gastroenterology. 140: S-713. DOI: 10.1016/S0016-5085(11)62961-2 |
0.642 |
|
| 2011 |
Sinnett-Smith J, Kisfalvi K, Young SH, Rozengurt E. Metformin Inhibits Mitogenic Signaling in Pancreatic Cancer Cells Through AMP-Stimulated Kinase Gastroenterology. 140: S-683. DOI: 10.1016/S0016-5085(11)62835-7 |
0.498 |
|
| 2011 |
Kisfalvi K, Sinnett-Smith J, Eibl G, Rozengurt E. Metformin Inhibits the Growth of Human Pancreatic Cancer Cells Implanted in Nu/Nu Mice Gastroenterology. 140: S-682. DOI: 10.1016/S0016-5085(11)62831-X |
0.318 |
|
| 2011 |
Sinnett-Smith J, Kui RK, Rozengurt E. Protein Kinase D1 Mediates Mitogenic Signaling in Intestinal Epithelial IEC-6 and IEC-18 Cells Gastroenterology. 140: S-632. DOI: 10.1016/S0016-5085(11)62612-7 |
0.491 |
|
| 2011 |
Rey O, Chang W, Bikle D, Rozengurt N, Moyer MP, Rozengurt E. The Extracellular Calcium-Sensing Receptor Regulates the Proliferation of Colonic Epithelial Cells In Vitro and In Vivo Gastroenterology. 140: S-482. DOI: 10.1016/S0016-5085(11)61987-2 |
0.36 |
|
| 2010 |
Zhang X, Rozengurt E, Reed EF. HLA class I molecules partner with integrin β4 to stimulate endothelial cell proliferation and migration. Science Signaling. 3: ra85. PMID 21098729 DOI: 10.1126/Scisignal.2001158 |
0.378 |
|
| 2010 |
Young SH, Rozengurt E. Crosstalk between insulin receptor and G protein-coupled receptor signaling systems leads to Ca²+ oscillations in pancreatic cancer PANC-1 cells. Biochemical and Biophysical Research Communications. 401: 154-8. PMID 20849815 DOI: 10.1016/J.Bbrc.2010.09.036 |
0.397 |
|
| 2010 |
Rey O, Young SH, Jacamo R, Moyer MP, Rozengurt E. Extracellular calcium sensing receptor stimulation in human colonic epithelial cells induces intracellular calcium oscillations and proliferation inhibition. Journal of Cellular Physiology. 225: 73-83. PMID 20648625 DOI: 10.1002/Jcp.22198 |
0.412 |
|
| 2010 |
Guha S, Tanasanvimon S, Sinnett-Smith J, Rozengurt E. Role of protein kinase D signaling in pancreatic cancer. Biochemical Pharmacology. 80: 1946-54. PMID 20621068 DOI: 10.1016/J.Bcp.2010.07.002 |
0.64 |
|
| 2010 |
Harikumar KB, Kunnumakkara AB, Ochi N, Tong Z, Deorukhkar A, Sung B, Kelland L, Jamieson S, Sutherland R, Raynham T, Charles M, Bagherzadeh A, Bagherazadeh A, Foxton C, Boakes A, ... ... Rozengurt E, et al. A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo. Molecular Cancer Therapeutics. 9: 1136-46. PMID 20442301 DOI: 10.1158/1535-7163.Mct-09-1145 |
0.616 |
|
| 2010 |
Rozengurt E, Sinnett-Smith J, Kisfalvi K. Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 2505-11. PMID 20388847 DOI: 10.1158/1078-0432.Ccr-09-2229 |
0.396 |
|
| 2010 |
Kisfalvi K, Hurd C, Guha S, Rozengurt E. Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells. Journal of Cellular Physiology. 223: 309-16. PMID 20082306 DOI: 10.1002/Jcp.22036 |
0.709 |
|
| 2010 |
Torres-Marquez E, Sinnett-Smith J, Guha S, Kui R, Waldron RT, Rey O, Rozengurt E. CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway. Biochemical and Biophysical Research Communications. 391: 63-8. PMID 19896460 DOI: 10.1016/J.Bbrc.2009.11.002 |
0.692 |
|
| 2010 |
Rey O, Chang W, Bikle D, Rozengurt N, Rozengurt E. Abstract A105: The extracellular calcium sensing receptor regulates the proliferation of colonic epithelial cells Cancer Epidemiology, Biomarkers & Prevention. 19. DOI: 10.1158/1055-9965.Disp-10-A105 |
0.394 |
|
| 2010 |
Rey O, Chang W, Bikle D, Rozengurt N, Rozengurt E. W1744 The Extracellular Calcium-Sensing Receptor Regulates the Proliferation of Normal Colonic Epithelial Cells and Reverses the Malignant Phenotype of Colon Cancer Cells Gastroenterology. 138: S-731. DOI: 10.1016/S0016-5085(10)63364-1 |
0.485 |
|
| 2010 |
Kisfalvi K, Sinnett-Smith J, Guha S, Rozengurt E. M1969 Induced Overexpression of Protein Kinase D1 Stimulates Mitogenic Signaling in Human Pancreatic Carcinoma PANC-1 Cells Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)62079-3 |
0.644 |
|
| 2010 |
Waldron RT, Peterson LB, Blagg B, Rozengurt E. M1705 Curcumin and Curcumin Analogues Inhibit Mitogenic Signaling in Normal Intestinal Epithelial Cells Gastroenterology. 138: S-402. DOI: 10.1016/S0016-5085(10)61848-3 |
0.371 |
|
| 2010 |
Sinnett-Smith J, Rozengurt E. S1710 Carbachol Induces P70s6k1 Activation Through an ERK-Dependent but AKT-Independent Pathway in Human Colonic Epithelial Cells Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)61180-8 |
0.453 |
|
| 2010 |
Sinnett-Smith J, Kui RK, Young SH, Rozengurt E. S1709 Sustained PKD Activation by Gq-Coupled Receptors is Mediated by PKC-Independent Regulation of Activation Loop Ser744 and Ser748 Phosphorylation Gastroenterology. 138: S-258. DOI: 10.1016/S0016-5085(10)61179-1 |
0.426 |
|
| 2010 |
Sinnett-Smith J, Kui RK, Rozengurt E. S1708 PKD Selectively Prolongs ERK Signaling and Potentiates DNA Synthesis in Response to Gq-Coupled Receptor Agonists Through a PKC-Independent but EGFR-Dependent Pathway Gastroenterology. 138: S-258. DOI: 10.1016/S0016-5085(10)61178-X |
0.407 |
|
| 2010 |
Torres-Marquez E, Sinnett-Smith J, Guha S, Rey O, Waldron RT, Rozengurt E. S1700 Cid755673 Enhances Mitogenic Signaling by Bombesin and EGF Through a Protein Kinase D-Independent Pathway Gastroenterology. 138: S-256. DOI: 10.1016/S0016-5085(10)61170-5 |
0.631 |
|
| 2010 |
Sinnett-Smith J, Kui RK, Young SH, Huang C, Rozengurt N, Rozengurt E. 751 Transgenic Protein Kinase D1 Stimulates the Rate of Epithelial Cell Proliferation in Intestinal Crypts Gastroenterology. 138: S-103. DOI: 10.1016/S0016-5085(10)60472-6 |
0.408 |
|
| 2010 |
Ireson CR, Harikumar KB, Kunnumakkara AB, Deorukhkar A, Tong Z, Maru D, Diagaradjane P, Ochi N, Krishnan S, Aggarwal BB, Rozengurt E, Guha S. 414 A Novel Small Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth Both In Vitro and In Vivo Gastroenterology. 138: S-62. DOI: 10.1016/S0016-5085(10)60282-X |
0.618 |
|
| 2009 |
Yoo J, Chung C, Slice L, Sinnett-Smith J, Rozengurt E. Protein kinase D mediates synergistic expression of COX-2 induced by TNF-{alpha} and bradykinin in human colonic myofibroblasts. American Journal of Physiology. Cell Physiology. 297: C1576-87. PMID 19794144 DOI: 10.1152/Ajpcell.00184.2009 |
0.399 |
|
| 2009 |
Kisfalvi K, Eibl G, Sinnett-Smith J, Rozengurt E. Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer Research. 69: 6539-45. PMID 19679549 DOI: 10.1158/0008-5472.Can-09-0418 |
0.456 |
|
| 2009 |
Jiang X, Sinnett-Smith J, Rozengurt E. Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. Biochemical and Biophysical Research Communications. 387: 521-4. PMID 19615971 DOI: 10.1016/J.Bbrc.2009.07.060 |
0.548 |
|
| 2009 |
Amadesi S, Grant AD, Cottrell GS, Vaksman N, Poole DP, Rozengurt E, Bunnett NW. Protein kinase D isoforms are expressed in rat and mouse primary sensory neurons and are activated by agonists of protease-activated receptor 2. The Journal of Comparative Neurology. 516: 141-56. PMID 19575452 DOI: 10.1002/Cne.22104 |
0.406 |
|
| 2009 |
Sinnett-Smith J, Jacamo R, Kui R, Wang YM, Young SH, Rey O, Waldron RT, Rozengurt E. Protein kinase D mediates mitogenic signaling by Gq-coupled receptors through protein kinase C-independent regulation of activation loop Ser744 and Ser748 phosphorylation. The Journal of Biological Chemistry. 284: 13434-45. PMID 19289471 DOI: 10.1074/Jbc.M806554200 |
0.539 |
|
| 2009 |
Sinnett-Smith J, Young SH, Jiang X, Rozengurt E. W1590 Protein Kinase D Activation and Function in Wounded Monolayers of Rat Intestinal IEC-18 and IEC-6 Cells Gastroenterology. 136: A-698. DOI: 10.1016/S0016-5085(09)63215-7 |
0.423 |
|
| 2009 |
Sinnett-Smith J, Kui RK, Young SH, Rozengurt N, Rozengurt E. M1604 Transgenic Expression of PKD Stimulates Intestinal Epithelial Cell Proliferation Gastroenterology. 136: A-393. DOI: 10.1016/S0016-5085(09)61804-7 |
0.392 |
|
| 2009 |
Lunn JA, Rozengurt E. M1600 Focal Adhesion Kinase (FAK) Plays a Critical Role in Early Cell Migration By Affecting the Microtubular Cytoskeleton Gastroenterology. 136: A-392. DOI: 10.1016/S0016-5085(09)61800-X |
0.392 |
|
| 2009 |
Kisfalvi K, Sinnett-Smith J, Eibl G, Rozengurt E. S2011 Metformin Inhibits the Growth of Human Pancreatic Cancer Cells In Vitro and In Vivo Gastroenterology. 136: A-312-A-313. DOI: 10.1016/S0016-5085(09)61427-X |
0.359 |
|
| 2009 |
Waldron RT, Rozengurt E. S1630 Curcumin Inhibition of PKD Family Kinases Gastroenterology. 136: A-238. DOI: 10.1016/S0016-5085(09)61076-3 |
0.375 |
|
| 2009 |
Jacamo R, Sinnett-Smith J, Rey O, Waldron RT, Innamorati G, Rozengurt E. S1629 Sequential PKC-Dependent and PKC-Independent Protein Kinase D Catalytic Activation via Gq-Coupled Receptors Gastroenterology. 136: A-238. DOI: 10.1016/S0016-5085(09)61075-1 |
0.457 |
|
| 2009 |
Sinnett-Smith J, Jacamo R, Kui RK, Rey O, Waldron RT, Rozengurt E. S1628 Protein Kinase D Mediates Mitogenic Signaling By Gq-Coupled Receptors Through PKC-Independent Regulation of Activation Loop Ser744 and Ser748 Phosphorylation Gastroenterology. 136: A-237-A-238. DOI: 10.1016/S0016-5085(09)61074-X |
0.489 |
|
| 2009 |
Jiang X, Sinnett-Smith J, Lunn JA, Rozengurt E. S1627 Carbachol Induces mTOR/S6k Activation Through An EGFR/AKT-Independent But ERK-Dependent Pathway in Human T84 Intestinal Epithelial Cells Gastroenterology. 136: A-237. DOI: 10.1016/S0016-5085(09)61073-8 |
0.462 |
|
| 2008 |
Yuan J, Lugea A, Zheng L, Gukovsky I, Edderkaoui M, Rozengurt E, Pandol SJ. Protein kinase D1 mediates NF-kappaB activation induced by cholecystokinin and cholinergic signaling in pancreatic acinar cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G1190-201. PMID 18845574 DOI: 10.1152/Ajpgi.90452.2008 |
0.448 |
|
| 2008 |
Papazyan R, Doche M, Waldron RT, Rozengurt E, Moyer MP, Rey O. Protein kinase D isozymes activation and localization during mitosis. Experimental Cell Research. 314: 3057-68. PMID 18692497 DOI: 10.1016/J.Yexcr.2008.07.014 |
0.478 |
|
| 2008 |
Jacamo R, Sinnett-Smith J, Rey O, Waldron RT, Rozengurt E. Sequential protein kinase C (PKC)-dependent and PKC-independent protein kinase D catalytic activation via Gq-coupled receptors: differential regulation of activation loop Ser(744) and Ser(748) phosphorylation. The Journal of Biological Chemistry. 283: 12877-87. PMID 18337243 DOI: 10.1074/Jbc.M800442200 |
0.518 |
|
| 2008 |
Jindra PT, Jin YP, Jacamo R, Rozengurt E, Reed EF. MHC class I and integrin ligation induce ERK activation via an mTORC2-dependent pathway. Biochemical and Biophysical Research Communications. 369: 781-7. PMID 18312854 DOI: 10.1016/J.Bbrc.2008.02.093 |
0.406 |
|
| 2008 |
Poole DP, Amadesi S, Rozengurt E, Thacker M, Bunnett NW, Furness JB. Stimulation of the neurokinin 3 receptor activates protein kinase C epsilon and protein kinase D in enteric neurons. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G1245-56. PMID 18308856 DOI: 10.1152/Ajpgi.00521.2007 |
0.447 |
|
| 2008 |
Sternini C, Anselmi L, Rozengurt E. Enteroendocrine cells: a site of 'taste' in gastrointestinal chemosensing. Current Opinion in Endocrinology, Diabetes, and Obesity. 15: 73-8. PMID 18185066 DOI: 10.1097/Med.0B013E3282F43A73 |
0.308 |
|
| 2008 |
Yuan J, Rozengurt E. PKD, PKD2, and p38 MAPK mediate Hsp27 serine-82 phosphorylation induced by neurotensin in pancreatic cancer PANC-1 cells. Journal of Cellular Biochemistry. 103: 648-62. PMID 17570131 DOI: 10.1002/Jcb.21439 |
0.488 |
|
| 2008 |
Wu SS, Vong SK, Rozengurt E. W1765 Protein Kinase C Mediates Feedback Inhibition of ERK Through EGFR Transactivation in Intestinal Epithelial Cells Gastroenterology. 134: A-711. DOI: 10.1016/S0016-5085(08)63319-3 |
0.491 |
|
| 2008 |
Pham H, Wu SS, Vincenti R, Rozengurt E, Slice LW. W1762 Basal Prostaglandin Levels Are Required for Pyk2 Expression and Ang II-Dependent MAPK Phosphorylation in Intestinal Epithelial Cells Gastroenterology. 134: A-710. DOI: 10.1016/S0016-5085(08)63316-8 |
0.412 |
|
| 2008 |
Jiang X, Sinnett-Smith J, Rozengurt E. W1760 Rapid FAK Phosphorylation On Ser-910 and Ser-843 in Intestinal Epithelial Cells Gastroenterology. 134: A-710. DOI: 10.1016/S0016-5085(08)63314-4 |
0.442 |
|
| 2008 |
Sinnett-Smith J, Young SH, Rozengurt E. W1759 Rapid Activation of Protein Kinase D in Response to Wounding of IEC-18 and IEC-6 Monolayers Gastroenterology. 134: A-709-A-710. DOI: 10.1016/S0016-5085(08)63313-2 |
0.407 |
|
| 2008 |
Kisfalvi K, Rozengurt E. M2021 Metformin Inhibits the Synergistic Effect of Insulin On Early and Late Cellular Events Induced By G-Protein Coupled Receptor Agonists in Human Pancreatic Cancer Cells Gastroenterology. 134: A-452. DOI: 10.1016/S0016-5085(08)62114-9 |
0.384 |
|
| 2008 |
Young SH, Sinnett-Smith J, Rozengurt E. S1693 Translocation of Phosphorylated Protein Kinase D (PKD) to the Plasma Membrane and Nucleus of Agonist Stimulated Iec18 and IEC6 Cells Monitored By Quantum Dot Conjugated Secondary Antibodies Gastroenterology. 134: A-251. DOI: 10.1016/S0016-5085(08)61164-6 |
0.398 |
|
| 2008 |
Sinnett-Smith J, Jacamo RO, Kui RK, Wang YM, Rozengurt E. S1691 Endogenous Protein Kinase D Contributes to Gq-Coupled Receptor Induction of DNA Synthesis in Swiss 3T3 Cells Gastroenterology. 134: A-251. DOI: 10.1016/S0016-5085(08)61162-2 |
0.497 |
|
| 2008 |
Waldron RT, Vincenti R, Pham H, Wu SS, Rozengurt E, Slice LW. S1690 Pyk2-Mediated, Direct Upstream Phosphorylation of FAK Tyr397 As a Novel Initiating Event for FAK Signal Transduction Responses to Prostaglandins in Intestinal Epithelial Cells Gastroenterology. 134: A-250-A-251. DOI: 10.1016/S0016-5085(08)61161-0 |
0.445 |
|
| 2008 |
Wu SS, Pham H, Vincenti R, Rozengurt E, Slice LW. S1689 Basal Prostaglandin Levels Are Necessary for Pyk2 Expression and Constitutive FAK Tyr-397 Phosphorylation in Intestinal Epithelial Cells Gastroenterology. 134: A-250. DOI: 10.1016/S0016-5085(08)61160-9 |
0.407 |
|
| 2008 |
De Giorgio R, Mazzoni M, Lalatta-Costerbosa G, Chiocchetti R, Barbara G, Bosi P, Gionchetti P, Rizzello F, Corinaldesi R, Stanghellini V, Campieri M, Rozengurt E, Sternini C, Clavenzani P. S1667 A-Transducin, a Signaling Molecule of the Chemoreceptive Cascade, Is Expressed in Endocrine and Non-Endocrine Cells of the Pig Gastrointestinal Mucosa Gastroenterology. 134: A-246. DOI: 10.1016/S0016-5085(08)61138-5 |
0.334 |
|
| 2008 |
Chen MC, Sternini C, Rozengurt E. S1658 Bitter Taste Receptor Agonists Denatonium Benzoate (DB) and Phenylthiocarbamide (PTC) Activate ERK Pathway Through Different Mechanisms in Enteroendocrine STC-1 Cells Gastroenterology. 134: A-243-A-244. DOI: 10.1016/S0016-5085(08)61129-4 |
0.402 |
|
| 2008 |
Hao S, Sharp JW, Chen MC, Rozengurt E, Sternini C, Raybould HE. 633 Agonists of Bitter Taste Receptors Activate Cellular Signaling in Endocrine Cells and Extrinsic Afferent Neurons in the Rat Gastroenterology. 134: A-90. DOI: 10.1016/S0016-5085(08)60423-0 |
0.344 |
|
| 2008 |
Lunn JA, Jacamo RO, Lee KG, Rozengurt E. 97 Focal Adhesion Kinase (FAK) Plays a Fundamental Role in Early Polarizing Events in Wound Healing: Elucidating the Requirement of FAK Serine 843 Phosphorylation Gastroenterology. 134: A-16. DOI: 10.1016/S0016-5085(08)60086-4 |
0.37 |
|
| 2008 |
Yoo J, Chung C, Sinnett-Smith J, Rozengurt E. 134. TNF-αPotentiates Bradykinin-Induced PKD Activation in Colonic Myofibroblasts Journal of Surgical Research. 144: 235. DOI: 10.1016/J.Jss.2007.12.152 |
0.306 |
|
| 2007 |
Rozengurt E, Sternini C. Taste receptor signaling in the mammalian gut. Current Opinion in Pharmacology. 7: 557-62. PMID 18024184 DOI: 10.1016/J.Coph.2007.10.002 |
0.388 |
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| 2007 |
Rozengurt E. Mitogenic signaling pathways induced by G protein-coupled receptors. Journal of Cellular Physiology. 213: 589-602. PMID 17786953 DOI: 10.1002/Jcp.21246 |
0.512 |
|
| 2007 |
Jin YP, Korin Y, Zhang X, Jindra PT, Rozengurt E, Reed EF. RNA interference elucidates the role of focal adhesion kinase in HLA class I-mediated focal adhesion complex formation and proliferation in human endothelial cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 7911-22. PMID 17548629 DOI: 10.4049/Jimmunol.178.12.7911 |
0.443 |
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| 2007 |
Kisfalvi K, Rey O, Young SH, Sinnett-Smith J, Rozengurt E. Insulin potentiates Ca2+ signaling and phosphatidylinositol 4,5-bisphosphate hydrolysis induced by Gq protein-coupled receptor agonists through an mTOR-dependent pathway. Endocrinology. 148: 3246-57. PMID 17379645 DOI: 10.1210/En.2006-1711 |
0.405 |
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| 2007 |
Waldron RT, Whitelegge JP, Faull KF, Rozengurt E. Identification of a novel phosphorylation site in c-jun directly targeted in vitro by protein kinase D. Biochemical and Biophysical Research Communications. 356: 361-7. PMID 17359934 DOI: 10.1016/J.Bbrc.2007.02.142 |
0.418 |
|
| 2007 |
Santiskulvong C, Rozengurt E. Protein kinase Calpha mediates feedback inhibition of EGF receptor transactivation induced by Gq-coupled receptor agonists. Cellular Signalling. 19: 1348-57. PMID 17307332 DOI: 10.1016/J.Cellsig.2007.01.006 |
0.787 |
|
| 2007 |
Lu YC, Rozengurt E, Zhukova E. Transgenic insulin released from G cells preferentially signals in the liver. Biochemical and Biophysical Research Communications. 355: 23-7. PMID 17291451 DOI: 10.1016/J.Bbrc.2007.01.059 |
0.36 |
|
| 2007 |
Lunn JA, Jacamo R, Rozengurt E. Preferential phosphorylation of focal adhesion kinase tyrosine 861 is critical for mediating an anti-apoptotic response to hyperosmotic stress. The Journal of Biological Chemistry. 282: 10370-9. PMID 17289681 DOI: 10.1074/Jbc.M607780200 |
0.474 |
|
| 2007 |
Jiang X, Sinnett-Smith J, Rozengurt E. Differential FAK phosphorylation at Ser-910, Ser-843 and Tyr-397 induced by angiotensin II, LPA and EGF in intestinal epithelial cells. Cellular Signalling. 19: 1000-10. PMID 17240116 DOI: 10.1016/J.Cellsig.2006.11.004 |
0.557 |
|
| 2007 |
Sinnett-Smith J, Zhukova E, Rey O, Rozengurt E. Protein kinase D2 potentiates MEK/ERK/RSK signaling, c-Fos accumulation and DNA synthesis induced by bombesin in Swiss 3T3 cells. Journal of Cellular Physiology. 211: 781-90. PMID 17226786 DOI: 10.1002/Jcp.20984 |
0.53 |
|
| 2007 |
Jacamo R, Jiang X, Lunn JA, Rozengurt E. FAK phosphorylation at Ser-843 inhibits Tyr-397 phosphorylation, cell spreading and migration. Journal of Cellular Physiology. 210: 436-44. PMID 17096371 DOI: 10.1002/Jcp.20870 |
0.474 |
|
| 2007 |
Chiu TT, Leung WY, Moyer MP, Strieter RM, Rozengurt E. Protein kinase D2 mediates lysophosphatidic acid-induced interleukin 8 production in nontransformed human colonic epithelial cells through NF-kappaB. American Journal of Physiology. Cell Physiology. 292: C767-77. PMID 16928771 DOI: 10.1152/Ajpcell.00308.2006 |
0.689 |
|
| 2006 |
Rey O, Young SH, Papazyan R, Shapiro MS, Rozengurt E. Requirement of the TRPC1 cation channel in the generation of transient Ca2+ oscillations by the calcium-sensing receptor. The Journal of Biological Chemistry. 281: 38730-7. PMID 17046820 DOI: 10.1074/Jbc.M605956200 |
0.323 |
|
| 2006 |
Rozengurt N, Wu SV, Chen MC, Huang C, Sternini C, Rozengurt E. Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G792-802. PMID 16728727 DOI: 10.1152/Ajpgi.00074.2006 |
0.396 |
|
| 2006 |
Rozengurt E. Taste receptors in the gastrointestinal tract. I. Bitter taste receptors and alpha-gustducin in the mammalian gut. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G171-7. PMID 16710053 DOI: 10.1152/Ajpgi.00073.2006 |
0.346 |
|
| 2006 |
Wu SS, Jácamo RO, Vong SK, Rozengurt E. Differential regulation of Pyk2 phosphorylation at Tyr-402 and Tyr-580 in intestinal epithelial cells: roles of calcium, Src, Rho kinase, and the cytoskeleton. Cellular Signalling. 18: 1932-40. PMID 16574377 DOI: 10.1016/J.Cellsig.2006.02.013 |
0.485 |
|
| 2006 |
Jiang X, Jacamo R, Zhukova E, Sinnett-Smith J, Rozengurt E. RNA interference reveals a differential role of FAK and Pyk2 in cell migration, leading edge formation and increase in focal adhesions induced by LPA in intestinal epithelial cells. Journal of Cellular Physiology. 207: 816-28. PMID 16508947 DOI: 10.1002/Jcp.20629 |
0.463 |
|
| 2006 |
Papazyan R, Rozengurt E, Rey O. The C-terminal tail of protein kinase D2 and protein kinase D3 regulates their intracellular distribution. Biochemical and Biophysical Research Communications. 342: 685-9. PMID 16494840 DOI: 10.1016/J.Bbrc.2006.02.013 |
0.407 |
|
| 2006 |
Rey O, Papazyan R, Waldron RT, Young SH, Lippincott-Schwartz J, Jacamo R, Rozengurt E. The nuclear import of protein kinase D3 requires its catalytic activity. The Journal of Biological Chemistry. 281: 5149-57. PMID 16380377 DOI: 10.1074/Jbc.M508014200 |
0.398 |
|
| 2006 |
Young SH, Rozengurt E. Qdot nanocrystal conjugates conjugated to bombesin or ANG II label the cognate G protein-coupled receptor in living cells. American Journal of Physiology. Cell Physiology. 290: C728-32. PMID 16236822 DOI: 10.1152/Ajpcell.00310.2005 |
0.366 |
|
| 2006 |
Yuan J, Rey O, Rozengurt E. Activation of protein kinase D3 by signaling through Rac and the alpha subunits of the heterotrimeric G proteins G12 and G13. Cellular Signalling. 18: 1051-62. PMID 16198087 DOI: 10.1016/J.Cellsig.2005.08.017 |
0.485 |
|
| 2005 |
Yuan J, Rey O, Rozengurt E. Protein kinase D3 activation and phosphorylation by signaling through G alpha q. Biochemical and Biophysical Research Communications. 335: 270-6. PMID 16081049 DOI: 10.1016/J.Bbrc.2005.06.209 |
0.354 |
|
| 2005 |
Jácamo RO, Rozengurt E. A truncated FAK lacking the FERM domain displays high catalytic activity but retains responsiveness to adhesion-mediated signals. Biochemical and Biophysical Research Communications. 334: 1299-304. PMID 16039608 DOI: 10.1016/J.Bbrc.2005.07.034 |
0.435 |
|
| 2005 |
Krysan K, Reckamp KL, Dalwadi H, Sharma S, Rozengurt E, Dohadwala M, Dubinett SM. Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner. Cancer Research. 65: 6275-81. PMID 16024629 DOI: 10.1158/0008-5472.Can-05-0216 |
0.551 |
|
| 2005 |
Wu SV, Chen MC, Rozengurt E. Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat. Physiological Genomics. 22: 139-49. PMID 15886333 DOI: 10.1152/Physiolgenomics.00030.2005 |
0.31 |
|
| 2005 |
Fan RS, Jácamo RO, Jiang X, Sinnett-Smith J, Rozengurt E. G protein-coupled receptor activation rapidly stimulates focal adhesion kinase phosphorylation at Ser-843. Mediation by Ca2+, calmodulin, and Ca2+/calmodulin-dependent kinase II. The Journal of Biological Chemistry. 280: 24212-20. PMID 15845548 DOI: 10.1074/Jbc.M500716200 |
0.496 |
|
| 2005 |
Rey O, Young SH, Yuan J, Slice L, Rozengurt E. Amino acid-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor are mediated by a phospholipase C/inositol 1,4,5-trisphosphate-independent pathway that requires G12, Rho, filamin-A, and the actin cytoskeleton. The Journal of Biological Chemistry. 280: 22875-82. PMID 15837785 DOI: 10.1074/Jbc.M503455200 |
0.34 |
|
| 2005 |
Guha S, Eibl G, Kisfalvi K, Fan RS, Burdick M, Reber H, Hines OJ, Strieter R, Rozengurt E. Broad-spectrum G protein-coupled receptor antagonist, [D-Arg1,D-Trp5,7,9,Leu11]SP: a dual inhibitor of growth and angiogenesis in pancreatic cancer. Cancer Research. 65: 2738-45. PMID 15805273 DOI: 10.1158/0008-5472.Can-04-3197 |
0.601 |
|
| 2005 |
Rozengurt E, Rey O, Waldron RT. Protein kinase D signaling. The Journal of Biological Chemistry. 280: 13205-8. PMID 15701647 DOI: 10.1036/1097-8542.Yb100018 |
0.449 |
|
| 2005 |
Slice LW, Chiu T, Rozengurt E. Angiotensin II and epidermal growth factor induce cyclooxygenase-2 expression in intestinal epithelial cells through small GTPases using distinct signaling pathways. The Journal of Biological Chemistry. 280: 1582-93. PMID 15525649 DOI: 10.1074/Jbc.M408172200 |
0.679 |
|
| 2005 |
Wu SS, Yamauchi K, Rozengurt E. Bombesin and angiotensin II rapidly stimulate Src phosphorylation at Tyr-418 in fibroblasts and intestinal epithelial cells through a PP2-insensitive pathway. Cellular Signalling. 17: 93-102. PMID 15451029 DOI: 10.1016/J.Cellsig.2004.06.001 |
0.533 |
|
| 2005 |
Kisfalvi K, Guha S, Rozengurt E. Neurotensin and EGF induce synergistic stimulation of DNA synthesis by increasing the duration of ERK signaling in ductal pancreatic cancer cells. Journal of Cellular Physiology. 202: 880-90. PMID 15389644 DOI: 10.1002/Jcp.20187 |
0.696 |
|
| 2005 |
Chiu T, Santiskulvong C, Rozengurt E. EGF receptor transactivation mediates ANG II-stimulated mitogenesis in intestinal epithelial cells through the PI3-kinase/Akt/mTOR/p70S6K1 signaling pathway. American Journal of Physiology. Gastrointestinal and Liver Physiology. 288: G182-94. PMID 15358595 DOI: 10.1152/Ajpgi.00200.2004 |
0.833 |
|
| 2004 |
Lepin EJ, Jin YP, Barwe SP, Rozengurt E, Reed EF. HLA class I signal transduction is dependent on Rho GTPase and ROK. Biochemical and Biophysical Research Communications. 323: 213-7. PMID 15351723 DOI: 10.1016/J.Bbrc.2004.08.082 |
0.418 |
|
| 2004 |
Lunn JA, Rozengurt E. Hyperosmotic stress induces rapid focal adhesion kinase phosphorylation at tyrosines 397 and 577. Role of Src family kinases and Rho family GTPases. The Journal of Biological Chemistry. 279: 45266-78. PMID 15302877 DOI: 10.1074/Jbc.M314132200 |
0.457 |
|
| 2004 |
Rey O, Reeve JR, Zhukova E, Sinnett-Smith J, Rozengurt E. G protein-coupled receptor-mediated phosphorylation of the activation loop of protein kinase D: dependence on plasma membrane translocation and protein kinase Cepsilon. The Journal of Biological Chemistry. 279: 34361-72. PMID 15190080 DOI: 10.1074/Jbc.M403265200 |
0.45 |
|
| 2004 |
Hunger-Glaser I, Fan RS, Perez-Salazar E, Rozengurt E. PDGF and FGF induce focal adhesion kinase (FAK) phosphorylation at Ser-910: dissociation from Tyr-397 phosphorylation and requirement for ERK activation. Journal of Cellular Physiology. 200: 213-22. PMID 15174091 DOI: 10.1002/Jcp.20018 |
0.514 |
|
| 2004 |
Santiskulvong C, Sinnett-Smith J, Rozengurt E. Insulin reduces the requirement for EGFR transactivation in bombesin-induced DNA synthesis. Biochemical and Biophysical Research Communications. 318: 826-32. PMID 15147945 DOI: 10.1016/J.Bbrc.2004.04.100 |
0.76 |
|
| 2004 |
Zhang L, Keane MP, Zhu LX, Sharma S, Rozengurt E, Strieter RM, Dubinett SM, Huang M. Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis. The Journal of Biological Chemistry. 279: 28315-9. PMID 15133032 DOI: 10.1074/Jbc.C400115200 |
0.324 |
|
| 2004 |
Jin YP, Fishbein MC, Said JW, Jindra PT, Rajalingam R, Rozengurt E, Reed EF. Anti-HLA class I antibody-mediated activation of the PI3K/Akt signaling pathway and induction of Bcl-2 and Bcl-xL expression in endothelial cells. Human Immunology. 65: 291-302. PMID 15120184 DOI: 10.1016/J.Humimm.2004.01.002 |
0.423 |
|
| 2004 |
Waldron RT, Rey O, Zhukova E, Rozengurt E. Oxidative stress induces protein kinase C-mediated activation loop phosphorylation and nuclear redistribution of protein kinase D. The Journal of Biological Chemistry. 279: 27482-93. PMID 15084589 DOI: 10.1074/Jbc.M402875200 |
0.461 |
|
| 2004 |
Sinnett-Smith J, Zhukova E, Hsieh N, Jiang X, Rozengurt E. Protein kinase D potentiates DNA synthesis induced by Gq-coupled receptors by increasing the duration of ERK signaling in swiss 3T3 cells. The Journal of Biological Chemistry. 279: 16883-93. PMID 14963034 DOI: 10.1074/Jbc.M313225200 |
0.556 |
|
| 2004 |
Kisfalvi K, Guha S, Rozengurt E. EFFECT OF NEUROTENSIN, BRADYKININ AND VASO-PRESSIN IN COMBINATION WITH EGF ON ERK SIGNALING, AND GROWTH OF HUMAN PANCREATIC CANCER. Pancreas. 29: 361. DOI: 10.1097/00006676-200411000-00134 |
0.569 |
|
| 2003 |
Santiskulvong C, Rozengurt E. Galardin (GM 6001), a broad-spectrum matrix metalloproteinase inhibitor, blocks bombesin- and LPA-induced EGF receptor transactivation and DNA synthesis in rat-1 cells. Experimental Cell Research. 290: 437-46. PMID 14568001 DOI: 10.1016/S0014-4827(03)00355-0 |
0.768 |
|
| 2003 |
Rey O, Zhukova E, Sinnett-Smith J, Rozengurt E. Vasopressin-induced intracellular redistribution of protein kinase D in intestinal epithelial cells. Journal of Cellular Physiology. 196: 483-92. PMID 12891705 DOI: 10.1002/Jcp.10323 |
0.526 |
|
| 2003 |
Guha S, Lunn JA, Santiskulvong C, Rozengurt E. Neurotensin stimulates protein kinase C-dependent mitogenic signaling in human pancreatic carcinoma cell line PANC-1. Cancer Research. 63: 2379-87. PMID 12750255 |
0.823 |
|
| 2003 |
Hunger-Glaser I, Salazar EP, Sinnett-Smith J, Rozengurt E. Bombesin, lysophosphatidic acid, and epidermal growth factor rapidly stimulate focal adhesion kinase phosphorylation at Ser-910: requirement for ERK activation. The Journal of Biological Chemistry. 278: 22631-43. PMID 12692126 DOI: 10.1074/Jbc.M210876200 |
0.521 |
|
| 2003 |
Rey O, Yuan J, Young SH, Rozengurt E. Protein kinase C nu/protein kinase D3 nuclear localization, catalytic activation, and intracellular redistribution in response to G protein-coupled receptor agonists. The Journal of Biological Chemistry. 278: 23773-85. PMID 12676944 DOI: 10.1074/Jbc.M300226200 |
0.505 |
|
| 2003 |
Rey O, Yuan J, Rozengurt E. Intracellular redistribution of protein kinase D2 in response to G-protein-coupled receptor agonists. Biochemical and Biophysical Research Communications. 302: 817-24. PMID 12646243 DOI: 10.1016/S0006-291X(03)00269-9 |
0.512 |
|
| 2003 |
Hurd C, Rozengurt E. Uncoupling of protein kinase D from suppression of EGF-dependent c-Jun phosphorylation in cancer cells. Biochemical and Biophysical Research Communications. 302: 800-4. PMID 12646240 DOI: 10.1016/S0006-291X(03)00268-7 |
0.512 |
|
| 2003 |
Chiu T, Santiskulvong C, Rozengurt E. ANG II stimulates PKC-dependent ERK activation, DNA synthesis, and cell division in intestinal epithelial cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G1-11. PMID 12620889 DOI: 10.1152/Ajpgi.00419.2002 |
0.835 |
|
| 2003 |
Salazar EP, Hunger-Glaser I, Rozengurt E. Dissociation of focal adhesion kinase and paxillin tyrosine phosphorylation induced by bombesin and lysophosphatidic acid from epidermal growth factor receptor transactivation in Swiss 3T3 cells. Journal of Cellular Physiology. 194: 314-24. PMID 12548551 DOI: 10.1002/Jcp.10204 |
0.52 |
|
| 2003 |
Yuan J, Slice LW, Gu J, Rozengurt E. Cooperation of Gq, Gi, and G12/13 in protein kinase D activation and phosphorylation induced by lysophosphatidic acid Journal of Biological Chemistry. 278: 4882-4891. PMID 12477719 DOI: 10.1074/Jbc.M211175200 |
0.532 |
|
| 2003 |
Waldron RT, Rozengurt E. Protein kinase C phosphorylates protein kinase D activation loop Ser744 and Ser748 and releases autoinhibition by the pleckstrin homology domain. The Journal of Biological Chemistry. 278: 154-63. PMID 12407104 DOI: 10.1074/Jbc.M208075200 |
0.459 |
|
| 2003 |
Chiu T, Santiskulvong C, Rozengurt E. Angiotensin II stimulates PKC-dependent ERK activation, DNA synthesis and cell division in intestinal epithelial cells Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)83088-3 |
0.81 |
|
| 2003 |
Guha S, Santiskulvong C, Rozengurt E. Neurotensin stimulates PKC-dependent and EGFR-independent ERK activation in human pancreatic cancer Gastroenterology. 124: A467. DOI: 10.1016/S0016-5085(03)82363-6 |
0.778 |
|
| 2003 |
Zhukova E, Sinnett-Smith J, Rozengurt E. Protein kinase D overexpression increases the duration of ERK signaling and potentiates DNA synthesis induced by bombesin in Swiss 3T3 cells Gastroenterology. 124: A466. DOI: 10.1016/S0016-5085(03)82356-9 |
0.489 |
|
| 2003 |
Wu SS, Rozengurt E. Phosphorylation of the focal adhesion-related kinase Pyk2 is Src-independent in intestinal epithelial cells Gastroenterology. 124: A465. DOI: 10.1016/S0016-5085(03)82351-X |
0.464 |
|
| 2003 |
Yuan J, Slice LW, Gu J, Rozengurt E. Cooperation of GQ, GI and G12/13 in pretem kinase D activation and phosphorylation induced by lysophosphatidic acid Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)80382-7 |
0.432 |
|
| 2002 |
Rozengurt E, Guha S, Sinnett-Smith J. Gastrointestinal peptide signalling in health and disease. The European Journal of Surgery. Supplement. : = Acta Chirurgica. Supplement. 23-38. PMID 16144198 |
0.649 |
|
| 2002 |
Young SH, Wu SV, Rozengurt E. Ca2+-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor require negative feedback by protein kinase C. The Journal of Biological Chemistry. 277: 46871-6. PMID 12356761 DOI: 10.1074/Jbc.M207083200 |
0.346 |
|
| 2002 |
Chen MC, Solomon TE, Perez Salazar E, Kui R, Rozengurt E, Soll AH. Secretin regulates paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G893-9. PMID 12223349 DOI: 10.1152/Ajpgi.00429.2001 |
0.477 |
|
| 2002 |
Jin YP, Singh RP, Du ZY, Rajasekaran AK, Rozengurt E, Reed EF. Ligation of HLA class I molecules on endothelial cells induces phosphorylation of Src, paxillin, and focal adhesion kinase in an actin-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 168: 5415-23. PMID 12023334 DOI: 10.4049/Jimmunol.168.11.5415 |
0.487 |
|
| 2002 |
Tangkijvanich P, Santiskulvong C, Melton AC, Rozengurt E, Yee HF. p38 MAP kinase mediates platelet-derived growth factor-stimulated migration of hepatic myofibroblasts. Journal of Cellular Physiology. 191: 351-61. PMID 12012331 DOI: 10.1002/Jcp.10112 |
0.771 |
|
| 2002 |
Wu SS, Chiu T, Rozengurt E. ANG II and LPA induce Pyk2 tyrosine phosphorylation in intestinal epithelial cells: Role of Ca2+, PKC, and Rho kinase American Journal of Physiology - Cell Physiology. 282. PMID 11997258 DOI: 10.1152/Ajpcell.00323.2001 |
0.711 |
|
| 2002 |
Hurd C, Waldron RT, Rozengurt E. Protein kinase D complexes with C-Jun N-terminal kinase via activation loop phosphorylation and phosphorylates the C-Jun N-terminus. Oncogene. 21: 2154-60. PMID 11948398 DOI: 10.1038/Sj.Onc.1205290 |
0.467 |
|
| 2002 |
Guha S, Rey O, Rozengurt E. Neurotensin induces protein kinase C-dependent protein kinase D activation and DNA synthesis in human pancreatic carcinoma cell line PANC-1. Cancer Research. 62: 1632-40. PMID 11912133 |
0.659 |
|
| 2002 |
Rozengurt E. Neuropeptides as growth factors for normal and cancerous cells. Trends in Endocrinology and Metabolism: Tem. 13: 128-34. PMID 11893527 DOI: 10.1016/S1043-2760(01)00544-6 |
0.475 |
|
| 2002 |
Yuan J, Bae D, Cantrell D, Nel AE, Rozengurt E. Protein kinase D is a downstream target of protein kinase Ctheta. Biochemical and Biophysical Research Communications. 291: 444-52. PMID 11855809 DOI: 10.1006/Bbrc.2002.6469 |
0.517 |
|
| 2002 |
Wu SV, Rozengurt N, Yang M, Young SH, Sinnett-Smith J, Rozengurt E. Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 2392-7. PMID 11854532 DOI: 10.1073/Pnas.042617699 |
0.381 |
|
| 2002 |
Chiu T, Wu SS, Santiskulvong C, Tangkijvanich P, Yee HF, Rozengurt E. Vasopressin-mediated mitogenic signaling in intestinal epithelial cells. American Journal of Physiology. Cell Physiology. 282: C434-50. PMID 11832328 DOI: 10.1152/Ajpcell.00240.2001 |
0.842 |
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| 2002 |
Wang Y, Waldron RT, Dhaka A, Patel A, Riley MM, Rozengurt E, Colicelli J. The RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins. Molecular and Cellular Biology. 22: 916-26. PMID 11784866 DOI: 10.1128/Mcb.22.3.916-926.2001 |
0.324 |
|
| 2002 |
Zhukova E, Sinnett-Smith J, Wong H, Chiu T, Rozengurt E. CCK(B)/gastrin receptor mediates synergistic stimulation of DNA synthesis and cyclin D1, D3, and E expression in Swiss 3T3 cells. Journal of Cellular Physiology. 189: 291-305. PMID 11748587 DOI: 10.1002/Jcp.10018 |
0.712 |
|
| 2001 |
Rey O, Sinnett-Smith J, Zhukova E, Rozengurt E. Regulated nucleocytoplasmic transport of protein kinase D in response to G protein-coupled receptor activation. The Journal of Biological Chemistry. 276: 49228-35. PMID 11641411 DOI: 10.1074/Jbc.M109395200 |
0.532 |
|
| 2001 |
Thomas W, Ascott ZK, Harmey D, Slice LW, Rozengurt E, Lax AJ. Cytotoxic necrotizing factor from Escherichia coli induces RhoA-dependent expression of the cyclooxygenase-2 Gene. Infection and Immunity. 69: 6839-45. PMID 11598057 DOI: 10.1128/Iai.69.11.6839-6845.2001 |
0.434 |
|
| 2001 |
Rey O, Rozengurt E. Protein kinase D interacts with Golgi via its cysteine-rich domain. Biochemical and Biophysical Research Communications. 287: 21-6. PMID 11549247 DOI: 10.1006/Bbrc.2001.5530 |
0.397 |
|
| 2001 |
Zhukova E, Sinnett-Smith J, Rozengurt E. Protein kinase D potentiates DNA synthesis and cell proliferation induced by bombesin, vasopressin, or phorbol esters in Swiss 3T3 cells. The Journal of Biological Chemistry. 276: 40298-305. PMID 11514571 DOI: 10.1074/Jbc.M106512200 |
0.537 |
|
| 2001 |
Yuan J, Slice LW, Rozengurt E. Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13. The Journal of Biological Chemistry. 276: 38619-27. PMID 11507098 DOI: 10.1074/Jbc.M105530200 |
0.512 |
|
| 2001 |
Santiskulvong C, Sinnett-Smith J, Rozengurt E. EGF receptor function is required in late G(1) for cell cycle progression induced by bombesin and bradykinin. American Journal of Physiology. Cell Physiology. 281: C886-98. PMID 11502566 DOI: 10.1152/Ajpcell.2001.281.3.C886 |
0.785 |
|
| 2001 |
Thomas W, Pullinger GD, Lax AJ, Rozengurt E. Escherichia coli cytotoxic necrotizing factor and Pasteurella multocida toxin induce focal adhesion kinase autophosphorylation and Src association. Infection and Immunity. 69: 5931-5. PMID 11500476 DOI: 10.1128/Iai.69.9.5931-5935.2001 |
0.46 |
|
| 2001 |
Young SH, Walsh JH, Rozengurt E, Slice LW. Agonist-dependent immobilization of chimeric bombesin/GRP receptors: dependence on c-Src activity and dissociation from internalization. Experimental Cell Research. 267: 37-44. PMID 11412036 DOI: 10.1006/Excr.2001.5245 |
0.374 |
|
| 2001 |
Rey O, Young SH, Cantrell D, Rozengurt E. Rapid protein kinase D translocation in response to G protein-coupled receptor activation. Dependence on protein kinase C. The Journal of Biological Chemistry. 276: 32616-26. PMID 11410587 DOI: 10.1074/Jbc.M101649200 |
0.481 |
|
| 2001 |
Waldron RT, Rey O, Iglesias T, Tugal T, Cantrell D, Rozengurt E. Activation loop Ser744 and Ser748 in protein kinase D are transphosphorylated in vivo. The Journal of Biological Chemistry. 276: 32606-15. PMID 11410586 DOI: 10.1074/Jbc.M101648200 |
0.499 |
|
| 2001 |
Hurd C, Rozengurt E. Protein kinase D is sufficient to suppress EGF-induced c-Jun Ser 63 phosphorylation. Biochemical and Biophysical Research Communications. 282: 404-8. PMID 11401472 DOI: 10.1006/Bbrc.2001.4591 |
0.493 |
|
| 2001 |
Sinnett-Smith J, Lunn JA, Leopoldt D, Rozengurt E. Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: dissociation from tyrosine phosphorylation of p130(CAS). Experimental Cell Research. 266: 292-302. PMID 11399057 DOI: 10.1006/Excr.2001.5219 |
0.485 |
|
| 2001 |
Leopoldt D, Yee HF, Rozengurt E. Calyculin-A induces focal adhesion assembly and tyrosine phosphorylation of p125(Fak), p130(Cas), and paxillin in Swiss 3T3 cells. Journal of Cellular Physiology. 188: 106-19. PMID 11382927 DOI: 10.1002/Jcp.1102 |
0.463 |
|
| 2001 |
Salazar EP, Rozengurt E. Src family kinases are required for integrin-mediated but not for G protein-coupled receptor stimulation of focal adhesion kinase autophosphorylation at Tyr-397. The Journal of Biological Chemistry. 276: 17788-95. PMID 11279163 DOI: 10.1074/Jbc.M100984200 |
0.541 |
|
| 2001 |
Chiu T, Rozengurt E. PKD in intestinal epithelial cells: rapid activation by phorbol esters, LPA, and angiotensin through PKC. American Journal of Physiology. Cell Physiology. 280: C929-42. PMID 11245610 DOI: 10.1152/Ajpcell.2001.280.4.C929 |
0.739 |
|
| 2001 |
Chiu T, Rozengurt E. CCK2 (CCKB/gastrin) receptor mediates rapid protein kinase D (PKD) activation through a protein kinase C-dependent pathway Febs Letters. 489: 101-106. PMID 11231022 DOI: 10.1016/S0014-5793(01)02076-2 |
0.726 |
|
| 2001 |
Rozengurt E, Walsh JH. Gastrin, CCK, signaling, and cancer. Annual Review of Physiology. 63: 49-76. PMID 11181948 DOI: 10.1146/Annurev.Physiol.63.1.49 |
0.533 |
|
| 2001 |
Ryder NM, Guha S, Hines OJ, Reber HA, Rozengurt E. G protein-coupled receptor signaling in human ductal pancreatic cancer cells: neurotensin responsiveness and mitogenic stimulation. Journal of Cellular Physiology. 186: 53-64. PMID 11147814 DOI: 10.1002/1097-4652(200101)186:1<53::Aid-Jcp1004>3.0.Co;2-Q |
0.647 |
|
| 2001 |
Iglesias T, Cabrera-Poch N, Mitchell MP, Naven TJ, Rozengurt E, Schiavo G. Identification and cloning of Kidins220, a novel neuronal substrate of protein kinase D. The Journal of Biological Chemistry. 275: 40048-56. PMID 10998417 DOI: 10.1074/Jbc.M005261200 |
0.479 |
|
| 2001 |
Chiu TT, Santiskulvong C, Rozengurt E. Angiotensin II is a potent growth factor for IEC-18 cells Gastroenterology. 120: A508. DOI: 10.1016/S0016-5085(08)82522-X |
0.772 |
|
| 2001 |
Zhukova E, Sinnett-Smith J, Bolles A, Wong H, Young S, Walsh JH, Rozengurt E. Activation of CCKb/gastrin receptor induces cell cycle progression in swiss 3T3 cells Gastroenterology. 120: A508. DOI: 10.1016/S0016-5085(08)82520-6 |
0.412 |
|
| 2001 |
Waldron RT, Cantrell D, Rozengurt E. Bombesin/GRP induces activation loop ser 748 phosphorylation in protein kinase D (PKD) Gastroenterology. 120: A500. DOI: 10.1016/S0016-5085(08)82481-X |
0.46 |
|
| 2001 |
Yuan J, Slice L, Rozengurt E. Activation of protein kinase D (PKD) by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13 Gastroenterology. 120: A499. DOI: 10.1016/S0016-5085(08)82478-X |
0.381 |
|
| 2001 |
Lunn JA, Wong H, Rozengurt E, Walsh JH. Cortical actin organization is required for internalization of bombesin/GRP and EGF receptors, and ERK activation in Swiss 3T3 cells Gastroenterology. 120: A310-A311. DOI: 10.1016/S0016-5085(08)81542-9 |
0.375 |
|
| 2001 |
Slice LW, Young SH, Rozengurt E. Agonist-induced immobilization of GRP receptors: Dependence on c-src and dissociation from internalization Gastroenterology. 120: A309. DOI: 10.1016/S0016-5085(08)81536-3 |
0.328 |
|
| 2001 |
Guha S, Rozengurt E. Protein kinase C (PKC) plays a pivotal role in neurotensin (NT) mediated signaling in human ductal pancreatic cancer cells Gastroenterology. 120: A309. DOI: 10.1016/S0016-5085(08)81535-1 |
0.642 |
|
| 2001 |
Wu SS, Rozengurt E. Angiotensin II and lysophosphatidic acid rapidly activate the cytosolic tyrosine kinase Pyk2 in intestinal epithelial cells Gastroenterology. 120: A308. DOI: 10.1016/S0016-5085(08)81531-4 |
0.459 |
|
| 2001 |
Chen MC, Perez-Salazar E, Kui R, Rozengurt E, Soll AH. Modulation of gastric mucosal paracellular permeability by secretin: Role of src family tyrosine kinase Gastroenterology. 120: A308. DOI: 10.1016/S0016-5085(08)81527-2 |
0.496 |
|
| 2000 |
Lunn JA, Wong H, Rozengurt E, Walsh JH. Requirement of cortical actin organization for bombesin, endothelin, and EGF receptor internalization. American Journal of Physiology. Cell Physiology. 279: C2019-27. PMID 11078719 DOI: 10.1152/Ajpcell.2000.279.6.C2019 |
0.424 |
|
| 2000 |
Haworth RS, Goss MW, Rozengurt E, Avkiran M. Expression and activity of protein kinase D/protein kinase C mu in myocardium: evidence for alpha1-adrenergic receptor- and protein kinase C-mediated regulation. Journal of Molecular and Cellular Cardiology. 32: 1013-23. PMID 10888254 DOI: 10.1006/Jmcc.2000.1143 |
0.431 |
|
| 2000 |
Sinnett-Smith J, Santiskulvong C, Duque J, Rozengurt E. [D-Arg(1),D-Trp(5,7,9),Leu(11)]Substance P inhibits bombesin-induced mitogenic signal transduction mediated by both G(q) and G(12) in Swiss 3T3cells. The Journal of Biological Chemistry. 275: 30644-52. PMID 10880515 DOI: 10.1074/Jbc.M003702200 |
0.747 |
|
| 2000 |
Matthews SA, Rozengurt E, Cantrell D. Protein kinase D. A selective target for antigen receptors and a downstream target for protein kinase C in lymphocytes. The Journal of Experimental Medicine. 191: 2075-82. PMID 10859332 DOI: 10.1084/Jem.191.12.2075 |
0.487 |
|
| 2000 |
Matthews SA, Iglesias T, Rozengurt E, Cantrell D. Spatial and temporal regulation of protein kinase D (PKD). The Embo Journal. 19: 2935-45. PMID 10856238 DOI: 10.1093/Emboj/19.12.2935 |
0.428 |
|
| 2000 |
Waldron RT, Rozengurt E. Oxidative stress induces protein kinase D activation in intact cells. Involvement of Src and dependence on protein kinase C. The Journal of Biological Chemistry. 275: 17114-21. PMID 10748111 DOI: 10.1074/Jbc.M908959199 |
0.483 |
|
| 2000 |
Leopoldt D, Yee HF, Saab S, Rozengurt E. Tyrosine phosphorylation of p125(Fak), p130(Cas), and paxillin does not require extracellular signal-regulated kinase activation in Swiss 3T3 cells stimulated by bombesin or platelet-derived growth factor. Journal of Cellular Physiology. 183: 208-20. PMID 10737896 DOI: 10.1002/(Sici)1097-4652(200005)183:2<208::Aid-Jcp7>3.0.Co;2-5 |
0.537 |
|
| 2000 |
Paolucci L, Sinnett-Smith J, Rozengurt E. Lysophosphatidic acid rapidly induces protein kinase D activation through a pertussis toxin-sensitive pathway. American Journal of Physiology. Cell Physiology. 278: C33-9. PMID 10644509 DOI: 10.1152/Ajpcell.2000.278.1.C33 |
0.528 |
|
| 2000 |
Yuan J, Slice L, Walsh JH, Rozengurt E. Activation of protein kinase D by signaling through the alpha subunit of the heterotrimeric G protein G(q). The Journal of Biological Chemistry. 275: 2157-64. PMID 10636921 DOI: 10.1074/jbc.275.3.2157 |
0.348 |
|
| 2000 |
Zhukova E, Sinnett-Smith J, Afshar AR, Young S, Wong H, Walsh JH, Rozengurt E. Synergistic proliferative effects of human CCKB receptor in Swiss 3T3 cells Regulatory Peptides. 94: 68. DOI: 10.1016/S0167-0115(00)80137-8 |
0.349 |
|
| 2000 |
Wu SV, Yang M, Walsh JH, Rozengurt E. Inhibition of cholecystokinin (CCK) binding and signaling by broad-spectrum substance P analogues is at the receptor level Gastroenterology. 118: A310-A311. DOI: 10.1016/S0016-5085(00)83330-2 |
0.314 |
|
| 2000 |
Chen MC, Kui R, Rozengurt E, Soll AH. Distinct signal transduction pathways mediate synergistic regulation of gastric mucosal paracellular permeability by EGF and secretin Gastroenterology. 118: A233. DOI: 10.1016/S0016-5085(00)83006-1 |
0.328 |
|
| 2000 |
Chiu TT, Rozengurt E. Lysophosphatidic acid rapidly induces protein kinase D activation through a pertussis toxin-sensitive pathway in IEC-6 cells Gastroenterology. 118: A179. DOI: 10.1016/S0016-5085(00)82793-6 |
0.482 |
|
| 2000 |
Waldron RT, Rozengurt E. Oxidative stress-mediated protein kinase D activation in GI tract model cell lines Gastroenterology. 118: A1140. DOI: 10.1016/S0016-5085(00)80373-X |
0.405 |
|
| 1999 |
Haworth RS, Sinnett-Smith J, Rozengurt E, Avkiran M. Protein kinase D inhibits plasma membrane Na/Hexchanger activity. American Journal of Physiology. Cell Physiology. 277: C1202-C1209. PMID 29591100 DOI: 10.1152/Ajpcell.1999.277.6.C1202 |
0.456 |
|
| 1999 |
Salazar EP, Rozengurt E. Bombesin and platelet-derived growth factor induce association of endogenous focal adhesion kinase with Src in intact Swiss 3T3 cells. The Journal of Biological Chemistry. 274: 28371-8. PMID 10497197 DOI: 10.1074/Jbc.274.40.28371 |
0.525 |
|
| 1999 |
Slice LW, Walsh JH, Rozengurt E. Galpha(13) stimulates Rho-dependent activation of the cyclooxygenase-2 promoter. The Journal of Biological Chemistry. 274: 27562-6. PMID 10488092 DOI: 10.1074/Jbc.274.39.27562 |
0.467 |
|
| 1999 |
Matthews SA, Rozengurt E, Cantrell D. Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/Protein kinase Cmu. The Journal of Biological Chemistry. 274: 26543-9. PMID 10473617 DOI: 10.1074/Jbc.274.37.26543 |
0.507 |
|
| 1999 |
Matthews S, Iglesias T, Cantrell D, Rozengurt E. Dynamic re-distribution of protein kinase D (PKD) as revealed by a GFP-PKD fusion protein: dissociation from PKD activation. Febs Letters. 457: 515-21. PMID 10471840 DOI: 10.1016/S0014-5793(99)01090-X |
0.452 |
|
| 1999 |
Iglesias T, Rozengurt E. Protein kinase D activation by deletion of its cysteine-rich motifs. Febs Letters. 454: 53-6. PMID 10413094 DOI: 10.1016/S0014-5793(99)00772-3 |
0.441 |
|
| 1999 |
Waldron RT, Iglesias T, Rozengurt E. Phosphorylation-dependent protein kinase D activation. Electrophoresis. 20: 382-90. PMID 10197446 DOI: 10.1002/(Sici)1522-2683(19990201)20:2<382::Aid-Elps382>3.0.Co;2-N |
0.513 |
|
| 1999 |
Rozengurt E. Autocrine loops, signal transduction, and cell cycle abnormalities in the molecular biology of lung cancer. Current Opinion in Oncology. 11: 116-22. PMID 10188076 DOI: 10.1097/00001622-199903000-00007 |
0.397 |
|
| 1999 |
Waldron RT, Iglesias T, Rozengurt E. The pleckstrin homology domain of protein kinase D interacts preferentially with the eta isoform of protein kinase C. The Journal of Biological Chemistry. 274: 9224-30. PMID 10092595 DOI: 10.1074/Jbc.274.14.9224 |
0.413 |
|
| 1999 |
Rozengurt E. Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists. Journal of Cellular Physiology. 177: 507-17. PMID 10092204 DOI: 10.1002/(Sici)1097-4652(199812)177:4<507::Aid-Jcp2>3.0.Co;2-K |
0.492 |
|
| 1998 |
Rozengurt E. V. Gastrointestinal peptide signaling through tyrosine phosphorylation of focal adhesion proteins. American Journal of Physiology. Gastrointestinal and Liver Physiology. 275: G177-G182. PMID 29585518 DOI: 10.1152/Ajpgi.1998.275.2.G177 |
0.451 |
|
| 1998 |
Iglesias T, Matthews S, Rozengurt E. Dissimilar phorbol ester binding properties of the individual cysteine-rich motifs of protein kinase D. Febs Letters. 437: 19-23. PMID 9804164 DOI: 10.1016/S0014-5793(98)01189-2 |
0.393 |
|
| 1998 |
Iglesias T, Waldron RT, Rozengurt E. Identification of in vivo phosphorylation sites required for protein kinase D activation. The Journal of Biological Chemistry. 273: 27662-7. PMID 9765302 DOI: 10.1074/Jbc.273.42.27662 |
0.497 |
|
| 1998 |
Casamassima A, Rozengurt E. Insulin-like growth factor I stimulates tyrosine phosphorylation of p130(Cas), focal adhesion kinase, and paxillin. Role of phosphatidylinositol 3'-kinase and formation of a p130(Cas).Crk complex. The Journal of Biological Chemistry. 273: 26149-56. PMID 9748296 DOI: 10.1074/Jbc.273.40.26149 |
0.435 |
|
| 1998 |
Rodríguez-Fernández JL, Rozengurt E. Bombesin, vasopressin, lysophosphatidic acid, and sphingosylphosphorylcholine induce focal adhesion kinase activation in intact Swiss 3T3 cells. The Journal of Biological Chemistry. 273: 19321-8. PMID 9668122 DOI: 10.1074/Jbc.273.30.19321 |
0.518 |
|
| 1998 |
Abedi H, Rozengurt E, Zachary I. Rapid activation of the novel serine/threonine protein kinase, protein kinase D by phorbol esters, angiotensin II and PDGF-BB in vascular smooth muscle cells. Febs Letters. 427: 209-12. PMID 9607313 DOI: 10.1016/S0014-5793(98)00427-X |
0.502 |
|
| 1998 |
Needham LK, Rozengurt E. Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate. The Journal of Biological Chemistry. 273: 14626-32. PMID 9603980 DOI: 10.1074/Jbc.273.23.14626 |
0.493 |
|
| 1998 |
Iglesias T, Rozengurt E. Protein kinase D activation by mutations within its pleckstrin homology domain. The Journal of Biological Chemistry. 273: 410-6. PMID 9417097 DOI: 10.1074/Jbc.273.1.410 |
0.387 |
|
| 1998 |
Seckl MJ, Rozengurt E. Substance P analogues act as broad-spectrum neuropeptide antagonists Letters in Peptide Science. 5: 199-204. DOI: 10.1007/Bf02443469 |
0.374 |
|
| 1997 |
Zugaza JL, Waldron RT, Sinnett-Smith J, Rozengurt E. Bombesin, vasopressin, endothelin, bradykinin, and platelet-derived growth factor rapidly activate protein kinase D through a protein kinase C-dependent signal transduction pathway. The Journal of Biological Chemistry. 272: 23952-60. PMID 9295346 DOI: 10.1074/Jbc.272.38.23952 |
0.569 |
|
| 1997 |
Tobias ES, Rozengurt E, Connell JM, Houslay MD. Co-transfection with protein kinase D confers phorbol-ester-mediated inhibition on glucagon-stimulated cAMP accumulation in COS cells transfected to overexpress glucagon receptors. The Biochemical Journal. 326: 545-51. PMID 9291130 DOI: 10.1042/Bj3260545 |
0.512 |
|
| 1997 |
Brooks G, Goss MW, Rozengurt E, Galiñanes M. Phorbol ester, but not ischemic preconditioning, activates protein kinase D in the rat heart. Journal of Molecular and Cellular Cardiology. 29: 2273-83. PMID 9281458 DOI: 10.1006/Jmcc.1997.0466 |
0.347 |
|
| 1997 |
Matthews SA, Pettit GR, Rozengurt E. Bryostatin 1 induces biphasic activation of protein kinase D in intact cells. The Journal of Biological Chemistry. 272: 20245-50. PMID 9242703 DOI: 10.1074/Jbc.272.32.20245 |
0.537 |
|
| 1997 |
Rozengurt E, Sinnett-Smith J, Zugaza JL. Protein kinase D: a novel target for diacylglycerol and phorbol esters. Biochemical Society Transactions. 25: 565-71. PMID 9191157 DOI: 10.1042/Bst0250565 |
0.4 |
|
| 1997 |
Charlesworth A, Rozengurt E. Bombesin and neuromedin B stimulate the activation of p42(mapk) and p74(raf-1) via a protein kinase C-independent pathway in Rat-1 cells. Oncogene. 14: 2323-9. PMID 9178908 DOI: 10.1038/Sj.Onc.1201075 |
0.502 |
|
| 1997 |
Mann DJ, Higgins T, Jones NC, Rozengurt E. Differential control of cyclins D1 and D3 and the cdk inhibitor p27Kip1 by diverse signalling pathways in Swiss 3T3 cells. Oncogene. 14: 1759-66. PMID 9150381 DOI: 10.1038/Sj.Onc.1201134 |
0.489 |
|
| 1997 |
Lacerda HM, Pullinger GD, Lax AJ, Rozengurt E. Cytotoxic necrotizing factor 1 from Escherichia coli and dermonecrotic toxin from Bordetella bronchiseptica induce p21(rho)-dependent tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 cells. The Journal of Biological Chemistry. 272: 9587-96. PMID 9083104 DOI: 10.1074/Jbc.272.14.9587 |
0.511 |
|
| 1997 |
Casamassima A, Rozengurt E. Tyrosine phosphorylation of p130(cas) by bombesin, lysophosphatidic acid, phorbol esters, and platelet-derived growth factor. Signaling pathways and formation of a p130(cas)-Crk complex. The Journal of Biological Chemistry. 272: 9363-70. PMID 9083073 DOI: 10.1074/Jbc.272.14.9363 |
0.409 |
|
| 1997 |
Withers DJ, Seufferlein T, Mann D, Garcia B, Jones N, Rozengurt E. Rapamycin dissociates p70(S6K) activation from DNA synthesis stimulated by bombesin and insulin in Swiss 3T3 cells. The Journal of Biological Chemistry. 272: 2509-14. PMID 8999966 DOI: 10.1074/Jbc.272.4.2509 |
0.509 |
|
| 1997 |
Seufferlein T, Withers DJ, Mann D, Rozengurt E. Dissociation of mitogen-activated protein kinase activation from p125 focal adhesion kinase tyrosine phosphorylation in Swiss 3T3 cells stimulated by bombesin, lysophosphatidic acid, and platelet-derived growth factor. Molecular Biology of the Cell. 7: 1865-75. PMID 8970151 DOI: 10.1091/Mbc.7.12.1865 |
0.546 |
|
| 1997 |
Seckl MJ, Higgins T, Rozengurt E. [D-Arg1,D-Trp5,7,9,Leu11]Substance P coordinately and reversibly inhibits bombesin- and vasopressin-induced signal transduction pathways in Swiss 3T3 cells. The Journal of Biological Chemistry. 271: 29453-60. PMID 8910612 DOI: 10.1074/Jbc.271.46.29453 |
0.421 |
|
| 1997 |
Rozengurt E. Neuropeptides, signal transduction and small cell lung cancer Lung Cancer. 18: 7. DOI: 10.1016/S0169-5002(97)83857-3 |
0.348 |
|
| 1996 |
Rodríguez-Fernández JL, Rozengurt E. Bombesin, bradykinin, vasopressin, and phorbol esters rapidly and transiently activate Src family tyrosine kinases in Swiss 3T3 cells. Dissociation from tyrosine phosphorylation of p125 focal adhesion kinase. The Journal of Biological Chemistry. 271: 27895-901. PMID 8910389 DOI: 10.1074/Jbc.271.44.27895 |
0.501 |
|
| 1996 |
Seufferlein T, Withers DJ, Rozengurt E. Reduced requirement of mitogen-activated protein kinase (MAPK) activity for entry into the S phase of the cell cycle in Swiss 3T3 fibroblasts stimulated by bombesin and insulin. The Journal of Biological Chemistry. 271: 21471-7. PMID 8702930 DOI: 10.1074/Jbc.271.35.21471 |
0.525 |
|
| 1996 |
Seckl MJ, Rozengurt E. Effect of tyrphostin combined with a substance P related antagonist on small cell lung cancer cell growth in vitro. European Journal of Cancer (Oxford, England : 1990). 342-5. PMID 8664052 DOI: 10.1016/0959-8049(95)00536-6 |
0.439 |
|
| 1996 |
Rankin S, Hooshmand-Rad R, Claesson-Welsh L, Rozengurt E. Requirement for phosphatidylinositol 3'-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin. The Journal of Biological Chemistry. 271: 7829-34. PMID 8631827 DOI: 10.1074/Jbc.271.13.7829 |
0.51 |
|
| 1996 |
Jones DA, Cummings J, Langdon SP, Maclellan AJ, Higgins T, Rozengurt E, Smyth JF. Metabolism of the broad-spectrum neuropeptide growth factor antagonist: [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-substance P. British Journal of Cancer. 73: 715-20. PMID 8611370 DOI: 10.1038/Bjc.1996.126 |
0.303 |
|
| 1996 |
Cummings J, MacLellan AJ, Jones DA, Langdon SP, Rozengurt E, Ritchie AA, Smyth JF. Pharmacokinetics, metabolism, tissue and tumour distribution of the neuropeptide growth factor antagonist [Arg6, D-Trp7,9, NmePhe8]- substance P(6-11) in nude mice bearing the H69 small-cell lung cancer xenograft. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 6: 595-602. PMID 8573540 DOI: 10.1093/Oxfordjournals.Annonc.A059250 |
0.32 |
|
| 1996 |
Lacerda HM, Lax AJ, Rozengurt E. Pasteurella multocida toxin, a potent intracellularly acting mitogen, induces p125FAK and paxillin tyrosine phosphorylation, actin stress fiber formation, and focal contact assembly in Swiss 3T3 cells. The Journal of Biological Chemistry. 271: 439-45. PMID 8550600 DOI: 10.1074/Jbc.271.1.439 |
0.479 |
|
| 1996 |
Withers DJ, Coppock HA, Seufferlein T, Smith DM, Bloom SR, Rozengurt E. Adrenomedullin stimulates DNA synthesis and cell proliferation via elevation of cAMP in Swiss 3T3 cells. Febs Letters. 378: 83-7. PMID 8549809 DOI: 10.1016/0014-5793(95)01427-6 |
0.527 |
|
| 1996 |
Rozengurt E, Sinnett-Smith J, Van Lint J, Valverde AM. Protein kinase D (PKD): a novel target for diacylglycerol and phorbol esters. Mutation Research. 333: 153-60. PMID 8538623 DOI: 10.1016/0027-5107(95)00141-7 |
0.477 |
|
| 1996 |
Withers D, Rozengurt E, Bloom S. Dissociation of Camp-Stimulated Mitogenesis from Activation of the Mitogen-Activated Protein Kinase (MAPK) Cascade Clinical Science. 91: 18P-18P. DOI: 10.1042/cs091018pa |
0.371 |
|
| 1996 |
Zugaza JL, Sinnett-Smith J, Van Lint J, Rozengurt E. Protein kinase D (PKD) activation in intact cells through a protein kinase C-dependent signal transduction pathway. The Embo Journal. 15: 6220-6230. DOI: 10.1002/J.1460-2075.1996.Tb01012.X |
0.559 |
|
| 1995 |
Seckl MJ, Morii N, Narumiya S, Rozengurt E. Guanosine 5'-3-O-(thio)triphosphate stimulates tyrosine phosphorylation of p125FAK and paxillin in permeabilized Swiss 3T3 cells. Role of p21rho. The Journal of Biological Chemistry. 270: 6984-90. PMID 7896849 DOI: 10.1074/Jbc.270.12.6984 |
0.459 |
|
| 1995 |
Van Lint JV, Sinnett-Smith J, Rozengurt E. Expression and characterization of PKD, a phorbol ester and diacylglycerol-stimulated serine protein kinase. The Journal of Biological Chemistry. 270: 1455-61. PMID 7836415 DOI: 10.1074/Jbc.270.3.1455 |
0.49 |
|
| 1995 |
Withers DJ, Bloom SR, Rozengurt E. Dissociation of cAMP-stimulated mitogenesis from activation of the mitogen-activated protein kinase cascade in Swiss 3T3 cells. The Journal of Biological Chemistry. 270: 21411-9. PMID 7673177 DOI: 10.1074/Jbc.270.36.21411 |
0.532 |
|
| 1995 |
Seufferlein T, Rozengurt E. Sphingosylphosphorylcholine rapidly induces tyrosine phosphorylation of p125FAK and paxillin, rearrangement of the actin cytoskeleton and focal contact assembly. Requirement of p21rho in the signaling pathway. The Journal of Biological Chemistry. 270: 24343-51. PMID 7592646 DOI: 10.1074/Jbc.270.41.24343 |
0.457 |
|
| 1995 |
Seufferlein T, Rozengurt E. Sphingosylphosphorylcholine activation of mitogen-activated protein kinase in Swiss 3T3 cells requires protein kinase C and a pertussis toxin-sensitive G protein. The Journal of Biological Chemistry. 270: 24334-42. PMID 7592645 DOI: 10.1074/Jbc.270.41.24334 |
0.537 |
|
| 1995 |
Herget T, Oehrlein SA, Pappin DJ, Rozengurt E, Parker PJ. The myristoylated alanine-rich C-kinase substrate (MARCKS) is sequentially phosphorylated by conventional, novel and atypical isotypes of protein kinase C. European Journal of Biochemistry. 233: 448-57. PMID 7588787 DOI: 10.1111/J.1432-1033.1995.448_2.X |
0.433 |
|
| 1995 |
Cummings J, MacLellan AJ, Langdon SP, Jones DA, Rozengurt E, Smyth JF. Processing of the neuropeptide growth factor antagonist [Arg6, D-Trp7.9, NmePhe8]-substance P (6-11) by a small cell lung cancer cell line (H69). Biochemical Pharmacology. 49: 1709-12. PMID 7540393 DOI: 10.1016/0006-2952(95)00074-A |
0.374 |
|
| 1995 |
Seckl MJ, Newman RH, Freemont PS, Rozengurt E. Substance P-related antagonists inhibit vasopressin and bombesin but not 5'-3-O-(thio)triphosphate-stimulated inositol phosphate production in Swiss 3T3 cells. Journal of Cellular Physiology. 163: 87-95. PMID 7534771 DOI: 10.1002/Jcp.1041630110 |
0.413 |
|
| 1995 |
Kiehne K, Rozengurt E. Down-regulation of bradykinin receptors and bradykinin-induced Ca2+ mobilization, tyrosine phosphorylation, and DNA synthesis by autocrine factors, tumor necrosis factor alpha, and interferon beta in Swiss 3T3 cells. Journal of Cellular Physiology. 162: 367-77. PMID 7532178 DOI: 10.1002/Jcp.1041620309 |
0.442 |
|
| 1994 |
Herget T, Sethi T, Wu SV, Walsh JH, Rozengurt E. Cholecystokinin stimulates Ca2+ mobilization and clonal growth in small cell lung cancer through CCKA and CCKB/gastrin receptors. Annals of the New York Academy of Sciences. 713: 283-97. PMID 8185170 DOI: 10.1111/J.1749-6632.1994.Tb44076.X |
0.352 |
|
| 1994 |
Ward PN, Higgins TE, Murphy AC, Mullan PB, Rozengurt E, Lax AJ. Mutation of a putative ADP-ribosylation motif in the Pasteurella multocida toxin does not affect mitogenic activity Febs Letters. 342: 81-84. PMID 8143855 DOI: 10.1016/0014-5793(94)80589-X |
0.354 |
|
| 1994 |
Valverde AM, Sinnett-Smith J, Van Lint J, Rozengurt E. Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain. Proceedings of the National Academy of Sciences of the United States of America. 91: 8572-6. PMID 8078925 DOI: 10.1073/Pnas.91.18.8572 |
0.435 |
|
| 1994 |
Kiehne K, Rozengurt E. Synergistic stimulation of DNA synthesis by bradykinin and vasopressin in Swiss 3T3 cells. Journal of Cellular Physiology. 160: 502-10. PMID 8077288 DOI: 10.1002/Jcp.1041600313 |
0.519 |
|
| 1994 |
Herget T, Broad S, Rozengurt E. Overexpression of the myristoylated alanine-rich C-kinase substrate in Rat1 cells increases sensitivity to calmodulin antagonists. European Journal of Biochemistry. 225: 549-56. PMID 7957169 DOI: 10.1111/J.1432-1033.1994.T01-1-00549.X |
0.433 |
|
| 1994 |
Herget T, Rozengurt E. Bombesin, endothelin and platelet-derived growth factor induce rapid translocation of the myristoylated alanine-rich C-kinase substrate in Swiss 3T3 cells. European Journal of Biochemistry. 225: 539-48. PMID 7957168 DOI: 10.1111/J.1432-1033.1994.00539.X |
0.52 |
|
| 1994 |
Rankin S, Morii N, Narumiya S, Rozengurt E. Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin. Febs Letters. 354: 315-9. PMID 7525357 DOI: 10.1016/0014-5793(94)01148-6 |
0.497 |
|
| 1993 |
Zachary I, Sinnett-Smith J, Rozengurt E. Vasopressin regulation of cell growth in Swiss 3T3 cells. Regulatory Peptides. 45: 231-6. PMID 8511348 DOI: 10.1016/0167-0115(93)90211-P |
0.38 |
|
| 1993 |
Herget T, Brooks SF, Broad S, Rozengurt E. Expression of the major protein kinase C substrate, the acidic 80-kilodalton myristoylated alanine-rich C kinase substrate, increases sharply when Swiss 3T3 cells move out of cycle and enter G0. Proceedings of the National Academy of Sciences of the United States of America. 90: 2945-9. PMID 8464911 DOI: 10.1073/Pnas.90.7.2945 |
0.47 |
|
| 1993 |
Walsh JH, Bouzyk M, Rozengurt E. Homologous desensitization of bombesin-induced increases in intracellular Ca2+ in quiescent Swiss 3T3 cells involves a protein kinase C-independent mechanism. Journal of Cellular Physiology. 156: 333-40. PMID 8393879 DOI: 10.1002/Jcp.1041560216 |
0.413 |
|
| 1993 |
Civan MM, Robbins J, Broad S, Rozengurt E, Brown DA. Whole-cell recording of neuroblastoma x glioma cells during downregulation of a major substrate, 80K/MARCKS, of protein kinase C. The Journal of Membrane Biology. 133: 51-9. PMID 8320719 DOI: 10.1007/Bf00231877 |
0.446 |
|
| 1993 |
Civan MM, Sinnett-Smith J, Bouzyk M, Rozengurt E. Bombesin treatment enhances vasopressin receptors in Swiss 3T3 cells. The American Journal of Physiology. 265: C1658-62. PMID 8279527 DOI: 10.1152/Ajpcell.1993.265.6.C1658 |
0.367 |
|
| 1993 |
Zachary I, Rozengurt E. Focal adhesion kinase (p125FAK): a point of convergence in the action of neuropeptides, integrins, and oncogenes. Cell. 71: 891-4. PMID 1458538 DOI: 10.1016/0092-8674(92)90385-P |
0.405 |
|
| 1993 |
Zachary I, Sinnett-Smith J, Rozengurt E. Characterization of the Bombesin/Gastrin-Releasing Peptide Receptor in Swiss 3T3 Fibroblasts Methods in Neurosciences. 11: 267-282. DOI: 10.1016/B978-0-12-185271-9.50021-6 |
0.418 |
|
| 1992 |
Higgins TE, Murphy AC, Staddon JM, Lax AJ, Rozengurt E. Pasteurella multocida toxin is a potent inducer of anchorage-independent cell growth Proceedings of the National Academy of Sciences of the United States of America. 89: 4240-4244. PMID 1584759 DOI: 10.1073/Pnas.89.10.4240 |
0.494 |
|
| 1992 |
Herget T, Brooks SF, Broad S, Rozengurt E. Relationship between the major protein kinase C substrates acidic 80-kDa protein-kinase-C substrate (80K) and myristoylated alanine-rich C-kinase substrate (MARCKS). Members of a gene family or equivalent genes in different species. European Journal of Biochemistry. 209: 7-14. PMID 1396720 DOI: 10.1111/J.1432-1033.1992.Tb17255.X |
0.327 |
|
| 1992 |
Rozengurt E. Growth factors and cell proliferation. Current Opinion in Cell Biology. 4: 161-5. PMID 1318056 DOI: 10.1016/0955-0674(92)90027-A |
0.494 |
|
| 1992 |
Albert DA, Rozengurt E. Synergistic and coordinate expression of the genes encoding ribonucleotide reductase subunits in Swiss 3T3 cells: effect of multiple signal-transduction pathways. Proceedings of the National Academy of Sciences of the United States of America. 89: 1597-601. PMID 1311843 DOI: 10.1073/Pnas.89.5.1597 |
0.449 |
|
| 1991 |
Lax AJ, Chanter N, Pullinger GD, Higgins T, Staddon JM, Rozengurt E. Sequence analysis of the potent mitogenic toxin of Pasteurella multocida. Febs Letters. 277: 59-64. PMID 2269370 DOI: 10.1016/0014-5793(90)80809-W |
0.37 |
|
| 1991 |
Coffer A, Sinnett-Smith J, Rozengurt E. Bombesin receptor from Swiss 3T3 cells. Affinity chromatography and reconstitution into phospholipid vesicles. Febs Letters. 275: 159-64. PMID 2175713 DOI: 10.1016/0014-5793(90)81462-W |
0.389 |
|
| 1991 |
Rozengurt E. Bombesin stimulation of mitogenesis. Specific receptors, signal transduction, and early events. The American Review of Respiratory Disease. 142: S11-5. PMID 2174658 DOI: 10.1164/Ajrccm/142.6_Pt_2.S11 |
0.508 |
|
| 1991 |
Stirpe F, Higgins T, Tazzari PL, Rozengurt E. Stimulation by xanthine oxidase of 3T3 Swiss fibroblasts and human lymphocytes. Experimental Cell Research. 192: 635-8. PMID 1988299 DOI: 10.1016/0014-4827(91)90086-A |
0.346 |
|
| 1991 |
Rozengurt E, Fabregat I, Coffer A, Gil J, Sinnett-Smith J. Mitogenic signalling through the bombesin receptor: role of a guanine nucleotide regulatory protein. Journal of Cell Science. Supplement. 13: 43-56. PMID 1964686 DOI: 10.1242/Jcs.1990.Supplement_13.6 |
0.417 |
|
| 1991 |
Staddon JM, Bouzyk MM, Rozengurt E. A novel approach to detect toxin-catalyzed ADP-ribosylation in intact cells: its use to study the action of Pasteurella multocida toxin. The Journal of Cell Biology. 115: 949-58. PMID 1835459 DOI: 10.1083/Jcb.115.4.949 |
0.335 |
|
| 1991 |
Gil J, Higgins T, Rozengurt E. Mastoparan, a novel mitogen for Swiss 3T3 cells, stimulates pertussis toxin-sensitive arachidonic acid release without inositol phosphate accumulation. The Journal of Cell Biology. 113: 943-50. PMID 1709171 DOI: 10.1083/Jcb.113.4.943 |
0.47 |
|
| 1991 |
Huschtscha L, Rozengurt E, Bodmer WF. Growth factor requirements of human colorectal tumour cells: relations to cellular differentiation. European Journal of Cancer (Oxford, England : 1990). 27: 1680-4. PMID 1664222 DOI: 10.1016/0277-5379(91)90445-J |
0.327 |
|
| 1991 |
Zachary I, Gil J, Lehmann W, Sinnett-Smith J, Rozengurt E. Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation in intact Swiss 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 4577-81. PMID 1647010 DOI: 10.1073/Pnas.88.11.4577 |
0.529 |
|
| 1991 |
Brooks S, Herget T, Erusalimsky J, Rozengurt E. Protein kinase C activation potently down-regulates the expression of its major substrate, 80K, in Swiss 3T3 cells. The Embo Journal. 10: 2497-2505. DOI: 10.1002/J.1460-2075.1991.Tb07789.X |
0.337 |
|
| 1990 |
Rozengurt E. Signal transduction pathways in mitogenesis. British Medical Bulletin. 45: 515-28. PMID 2557118 DOI: 10.1093/Oxfordjournals.Bmb.A072339 |
0.465 |
|
| 1990 |
Brooks SF, Erusalimsky JD, Totty NF, Rozengurt E. Purification and internal amino acid sequence of the 80 kDa protein kinase C substrate from Swiss 3T3 fibroblasts. Homology with substrates from brain. Febs Letters. 268: 291-5. PMID 2384168 DOI: 10.1016/0014-5793(90)81030-R |
0.34 |
|
| 1990 |
Mehmet H, Millar JB, Lehmann W, Higgins T, Rozengurt E. Bombesin stimulation of c-fos expression and mitogenesis in Swiss 3T3 cells: the role of prostaglandin E2-mediated cyclic AMP accumulation. Experimental Cell Research. 190: 265-70. PMID 2170155 DOI: 10.1016/0014-4827(90)90195-G |
0.465 |
|
| 1990 |
Mehmet H, Nånberg E, Lehmann W, Murray MJ, Rozengurt E. Early signals in the mitogenic response of Swiss 3T3 cells: a comparative study of purified PDGF homodimers. Growth Factors (Chur, Switzerland). 3: 83-95. PMID 2169773 DOI: 10.3109/08977199009108271 |
0.444 |
|
| 1990 |
Nånberg E, Morris C, Higgins T, Vara F, Rozengurt E. Fibroblast growth factor stimulates protein kinase C in quiescent 3T3 cells without Ca2+ mobilization or inositol phosphate accumulation. Journal of Cellular Physiology. 143: 232-42. PMID 2159012 DOI: 10.1002/Jcp.1041430206 |
0.508 |
|
| 1990 |
Coffer A, Fabregat I, Sinnett-Smith J, Rozengurt E. Solubilization of the bombesin receptor from Swiss 3T3 cell membranes. Functional association to a guanine nucleotide regulatory protein. Febs Letters. 263: 80-4. PMID 2158908 DOI: 10.1016/0014-5793(90)80710-Z |
0.346 |
|
| 1990 |
Fabregat I, Rozengurt E. Vasoactive intestinal contractor, a novel peptide, shares a common receptor with endothelin-1 and stimulates Ca2+ mobilization and DNA synthesis in Swiss 3T3 cells. Biochemical and Biophysical Research Communications. 167: 161-7. PMID 2155611 DOI: 10.1016/0006-291X(90)91745-E |
0.374 |
|
| 1990 |
Sinnett-Smith J, Lehmann W, Rozengurt E. Bombesin receptor in membranes from Swiss 3T3 cells. Binding characteristics, affinity labelling and modulation by guanine nucleotides. The Biochemical Journal. 265: 485-93. PMID 2154190 DOI: 10.1042/Bj2650485 |
0.361 |
|
| 1990 |
Rozengurt E, Higgins T, Chanter N, Lax AJ, Staddon JM. Pasteurella multocida toxin: potent mitogen for cultured fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 87: 123-7. PMID 2153282 DOI: 10.1073/Pnas.87.1.123 |
0.441 |
|
| 1990 |
Rozengurt E, Sinnett-Smith J. Bombesin stimulation of fibroblast mitogenesis: specific receptors, signal transduction and early events. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 327: 209-21. PMID 1969660 DOI: 10.1098/rstb.1990.0055 |
0.386 |
|
| 1990 |
Fabregat I, Rozengurt E. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, a neuropeptide antagonist, blocks binding, Ca2(+)-mobilizing, and mitogenic effects of endothelin and vasoactive intestinal contractor in mouse 3T3 cells. Journal of Cellular Physiology. 145: 88-94. PMID 1698796 DOI: 10.1002/Jcp.1041450113 |
0.348 |
|
| 1989 |
Rozengurt E, Sinnett-Smith J. Early signals underlying the induction of the c-fos and c-myc genes in quiescent fibroblasts: studies with bombesin and other growth factors. Progress in Nucleic Acid Research and Molecular Biology. 35: 261-95. PMID 3065825 DOI: 10.1016/S0079-6603(08)60616-9 |
0.442 |
|
| 1989 |
Sinnett-Smith J, Zachary I, Rozengurt E. Characterization of a bombesin receptor on Swiss mouse 3T3 cells by affinity cross-linking. Journal of Cellular Biochemistry. 38: 237-49. PMID 2853712 DOI: 10.1002/Jcb.240380403 |
0.323 |
|
| 1989 |
Rozengurt E. Bombesin-induction of cell proliferation in 3T3 cells. Specific receptors and early signaling events. Annals of the New York Academy of Sciences. 547: 277-92. PMID 2853592 DOI: 10.1111/J.1749-6632.1988.Tb23896.X |
0.404 |
|
| 1989 |
Gonzalez FA, Rozengurt E, Heppel LA. Extracellular ATP induces the release of calcium from intracellular stores without the activation of protein kinase C in Swiss 3T6 mouse fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 86: 4530-4534. PMID 2734303 DOI: 10.1073/Pnas.86.12.4530 |
0.38 |
|
| 1989 |
Mehmet H, Taylor-Papadimitriou J, Rozengurt E. Interferon inhibition of bombesin-stimulated mitogenesis in Swiss 3T3 cells occurs without blocking c-fos and c-myc expression. Journal of Interferon Research. 9: 205-13. PMID 2715673 DOI: 10.1089/Jir.1989.9.205 |
0.452 |
|
| 1989 |
Erusalimsky JD, Morris C, Perks K, Brown R, Brooks S, Rozengurt E. Internal amino acid sequence analysis of the 80 kDa protein kinase C substrate from rat brain: relationship to the 87 kDa substrate from bovine brain. Febs Letters. 255: 149-53. PMID 2676596 DOI: 10.1016/0014-5793(89)81079-8 |
0.327 |
|
| 1989 |
Issandou M, Rozengurt E. Diacylglycerols, unlike phorbol esters, do not induce homologous desensitization or down-regulation of protein kinase C in Swiss 3T3 cells. Biochemical and Biophysical Research Communications. 163: 201-8. PMID 2673235 DOI: 10.1016/0006-291X(89)92121-9 |
0.525 |
|
| 1989 |
Woll PJ, Rozengurt E. Neuropeptides as growth regulators British Medical Bulletin. 45: 492-505. PMID 2557117 DOI: 10.1093/Oxfordjournals.Bmb.A072337 |
0.426 |
|
| 1989 |
Rozengurt E, Ober SS. Mitogenic signalling in murine 3T3 cells: the cyclic AMP pathway. Biochemical Society Transactions. 17: 629-32. PMID 2548903 DOI: 10.1042/Bst0170629 |
0.401 |
|
| 1989 |
Millar JB, Rozengurt E. Heterologous desensitization of bombesin-induced mitogenesis by prolonged exposure to vasopressin: a post-receptor signal transduction block. Proceedings of the National Academy of Sciences of the United States of America. 86: 3204-8. PMID 2541435 DOI: 10.1073/Pnas.86.9.3204 |
0.394 |
|
| 1989 |
Erusalimsky JD, Rozengurt E. Vasopressin rapidly stimulates protein kinase C in digitonin-permeabilized Swiss 3T3 cells: involvement of a pertussis toxin-insensitive guanine nucleotide binding protein. Journal of Cellular Physiology. 141: 253-61. PMID 2530240 DOI: 10.1002/Jcp.1041410204 |
0.514 |
|
| 1989 |
Woll PJ, Rozengurt E. Multiple neuropeptides mobilise calcium in small cell lung cancer: Effects of vasopressin, bradykinin, cholecystokinin, galanin and neurotensin Biochemical and Biophysical Research Communications. 164: 66-73. PMID 2478133 DOI: 10.1016/0006-291X(89)91683-5 |
0.351 |
|
| 1989 |
Woll PJ, Rozengurt E. Therapeutic implications of growth factors in small cell lung cancer Lung Cancer. 5: 287-295. DOI: 10.1016/0169-5002(89)90179-7 |
0.369 |
|
| 1988 |
Morris C, Rozengurt E. Purification of a phosphoprotein from rat brain closely related to the 80 kDa substrate of protein kinase C identified in Swiss 3T3 fibroblasts. Febs Letters. 231: 311-6. PMID 3360139 DOI: 10.1016/0014-5793(88)80840-8 |
0.384 |
|
| 1988 |
Morris C, Rice P, Rozengurt E. The diacylglycerol kinase inhibitor R 59022 potentiates bombesin stimulation of protein kinase C activity and DNA synthesis in Swiss 3T3 cells. Biochemical and Biophysical Research Communications. 155: 561-8. PMID 3262339 DOI: 10.1016/S0006-291X(88)80531-X |
0.494 |
|
| 1988 |
Millar JB, Rozengurt E. Bombesin enhancement of cAMP accumulation in Swiss 3T3 cells: evidence of a dual mechanism of action. Journal of Cellular Physiology. 137: 214-22. PMID 2848040 DOI: 10.1002/Jcp.1041370203 |
0.508 |
|
| 1988 |
Woll PJ, Coy DH, Rozengurt E. [Leu13-ψ(CH2NH)Leu14]bombesin is a specific bombesin receptor antagonist in Swiss 3T3 cells Biochemical and Biophysical Research Communications. 155: 359-365. PMID 2843183 DOI: 10.1016/S0006-291X(88)81093-3 |
0.443 |
|
| 1988 |
Woll PJ, Rozengurt E. Bombesin and bombesin antagonists: Studies in swiss 3T3 cells and human small cell lung cancer British Journal of Cancer. 57: 579-586. PMID 2841962 DOI: 10.1038/Bjc.1988.132 |
0.404 |
|
| 1988 |
Zurier RB, Kozma M, Sinnett-Smith J, Rozengurt E. Vasoactive intestinal peptide synergistically stimulates DNA synthesis in mouse 3T3 cells: role of cAMP, Ca2+, and protein kinase C. Experimental Cell Research. 176: 155-61. PMID 2836226 DOI: 10.1016/0014-4827(88)90129-2 |
0.493 |
|
| 1988 |
Millar J, Rozengurt E. Protein kinase C and cyclic AMP pathways cross-talk. Nature. 331: 492. PMID 2829027 DOI: 10.1038/331492B0 |
0.416 |
|
| 1988 |
Woll PJ, Rozengurt E. Two classes of antagonist interact with receptors for the mitogenic neuropeptides bombesin, bradykinin, and vasopressin Growth Factors. 1: 75-83. PMID 2483337 DOI: 10.3109/08977198809000249 |
0.39 |
|
| 1988 |
Escribano J, Rozengurt E. Cyclic AMP increasing agents rapidly stimulate vimentin phosphorylation in quiescent cultures of Swiss 3T3 cells. Journal of Cellular Physiology. 137: 223-34. PMID 2461373 DOI: 10.1002/jcp.1041370204 |
0.377 |
|
| 1988 |
Woll PJ, Rozengurt E. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro Proceedings of the National Academy of Sciences of the United States of America. 85: 1859-1863. PMID 2450349 DOI: 10.1073/Pnas.85.6.1859 |
0.359 |
|
| 1988 |
Nånberg E, Rozengurt E. Temporal relationship between inositol polyphosphate formation and increases in cytosolic Ca2+ in quiescent 3T3 cells stimulated by platelet-derived growth factor, bombesin and vasopressin. The Embo Journal. 7: 2741-2747. DOI: 10.1002/J.1460-2075.1988.Tb03128.X |
0.365 |
|
| 1987 |
Stabel S, Rodriguez-Pena A, Young S, Rozengurt E, Parker PJ. Quantitation of protein kinase C by immunoblot--expression in different cell lines and response to phorbol esters. Journal of Cellular Physiology. 130: 111-7. PMID 3543027 DOI: 10.1002/Jcp.1041300116 |
0.477 |
|
| 1987 |
Mehmet H, Morris CM, Taylor-Papadimitriou J, Rozengurt E. Interferon inhibition of DNA synthesis in Swiss 3T3 cells: Dissociation from protein kinase C activation Biochemical and Biophysical Research Communications. 145: 1026-1032. PMID 3496878 DOI: 10.1016/0006-291X(87)91538-5 |
0.511 |
|
| 1987 |
Rozengurt E, Sinnett-Smith JW. Bombesin induction of c-fos and c-myc proto-oncogenes in Swiss 3T3 cells: significance for the mitogenic response. Journal of Cellular Physiology. 131: 218-25. PMID 3108267 DOI: 10.1002/Jcp.1041310211 |
0.406 |
|
| 1987 |
Zachary I, Millar J, Nånberg E, Higgins T, Rozengurt E. Inhibition of bombesin-induced mitogenesis by pertussis toxin: dissociation from phospholipase C pathway. Biochemical and Biophysical Research Communications. 146: 456-63. PMID 3039979 DOI: 10.1016/0006-291X(87)90551-1 |
0.448 |
|
| 1987 |
Lopez-Rivas A, Mendoza SA, Nånberg E, Sinnett-Smith J, Rozengurt E. Ca2+-mobilizing actions of platelet-derived growth factor differ from those of bombesin and vasopressin in Swiss 3T3 mouse cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 5768-72. PMID 3039507 DOI: 10.1073/Pnas.84.16.5768 |
0.345 |
|
| 1987 |
Rozengurt E, Murray M, Zachary I, Collins M. Protein kinase C activation enhances cAMP accumulation in Swiss 3T3 cells: inhibition by pertussis toxin. Proceedings of the National Academy of Sciences of the United States of America. 84: 2282-6. PMID 3031676 DOI: 10.1073/Pnas.84.8.2282 |
0.496 |
|
| 1987 |
Zachary I, Woll PJ, Rozengurt E. A role for neuropeptides in the control of cell proliferation Developmental Biology. 124: 295-308. PMID 2824251 DOI: 10.1016/0012-1606(87)90483-0 |
0.332 |
|
| 1986 |
Civan MM, Williams SR, Gadian DG, Rozengurt E. 31P NMR analysis of intracellular pH of Swiss Mouse 3T3 cells: effects of extracellular Na+ and K+ and mitogenic stimulation. The Journal of Membrane Biology. 94: 55-64. PMID 3543375 DOI: 10.1007/Bf01901013 |
0.401 |
|
| 1986 |
Rodriguez-Pena A, Zachary I, Rozengurt E. Rapid dephosphorylation of a Mr 80,000 protein, a specific substrate of protein kinase C upon removal of phorbol esters, bombesin and vasopressin. Biochemical and Biophysical Research Communications. 140: 379-85. PMID 3465323 DOI: 10.1016/0006-291X(86)91101-0 |
0.458 |
|
| 1986 |
Mendoza SA, Lopez-Rivas A, Sinnett-Smith JW, Rozengurt E. Phorbol esters and diacylglycerol inhibit vasopressin-induced increases in cytoplasmic-free Ca2+ and 45Ca2+ efflux in Swiss 3T3 cells. Experimental Cell Research. 164: 536-45. PMID 3458589 DOI: 10.1016/0014-4827(86)90051-0 |
0.397 |
|
| 1986 |
Zachary I, Sinnett-Smith JW, Rozengurt E. Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. I. Activation of protein kinase C and inhibition of epidermal growth factor binding. The Journal of Cell Biology. 102: 2211-22. PMID 3011811 DOI: 10.1083/Jcb.102.6.2211 |
0.474 |
|
| 1986 |
Rozengurt E, Rodriguez-Peña A, Sinnett-Smith J. Signalling mitogenesis in 3T3 cells: role of Ca2+-sensitive, phospholipid-dependent protein kinase. Ciba Foundation Symposium. 116: 66-86. PMID 3000709 DOI: 10.1002/9780470720974.ch5 |
0.471 |
|
| 1986 |
Rodriguez-Pena A, Rozengurt E. Vasopressin rapidly stimulates protein kinase C in quiescent Swiss 3T3 cells. Journal of Cellular Physiology. 129: 124-30. PMID 2944907 DOI: 10.1002/Jcp.1041290117 |
0.477 |
|
| 1986 |
Ebsworth N, Rozengurt E, Taylor-Papadimitriou J. Measurement of the antiproliferative effect of interferon: influence of growth factors. Methods in Enzymology. 119: 643-9. PMID 2429160 DOI: 10.1016/0076-6879(86)19086-0 |
0.401 |
|
| 1986 |
Zachary I, Rozengurt E. A substance P antagonist also inhibits specific binding and mitogenic effects of vasopressin and bombesin-related peptides in Swiss 3T3 cells. Biochemical and Biophysical Research Communications. 137: 135-41. PMID 2424443 DOI: 10.1016/0006-291X(86)91186-1 |
0.342 |
|
| 1986 |
Mendoza SA, Schneider JA, Lopez-Rivas A, Sinnett-Smith JW, Rozengurt E. Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. II. Changes in Na+ and Ca2+ fluxes, Na+/K+ pump activity, and intracellular pH. The Journal of Cell Biology. 102: 2223-33. PMID 2423536 DOI: 10.1083/Jcb.102.6.2223 |
0.354 |
|
| 1986 |
Ebsworth N, Rozengurt E, Taylor-Papadimitriou J. Microtubule-disrupting agents reverse the inhibitory effect of interferon on mitogenesis in 3T3 cells. Experimental Cell Research. 165: 255-9. PMID 2423352 DOI: 10.1016/0014-4827(86)90549-5 |
0.382 |
|
| 1986 |
Taylor-Papadimitriou J, Balkwill F, Ebsworth N, Rozengurt E. Antiviral and antiproliferative effects of interferons in quiescent fibroblasts are dissociable. Virology. 147: 405-12. PMID 2416119 DOI: 10.1016/0042-6822(85)90142-4 |
0.393 |
|
| 1986 |
Rozengurt E, Mendoza SA. Chapter 5 Early Stimulation of Na+-H+Antiport, Na+-K+Pump Activity, and Ca2+Fluxes in Fibroblast Mitogenesis Current Topics in Membranes and Transport. 27: 163-191. DOI: 10.1016/S0070-2161(08)60356-1 |
0.386 |
|
| 1986 |
Rodriguez-Pena A, Rozengurt E. Phosphorylation of an acidic mol. wt. 80 000 cellular protein in a cell-free system and intact Swiss 3T3 cells: a specific marker of protein kinase C activity. The Embo Journal. 5: 77-83. DOI: 10.1002/j.1460-2075.1986.tb04180.x |
0.376 |
|
| 1985 |
Rozengurt E, Mendoza SA. Synergistic signals in mitogenesis: role of ion fluxes, cyclic nucleotides and protein kinase C in Swiss 3T3 cells. Journal of Cell Science. Supplement. 3: 229-42. PMID 3011824 DOI: 10.1242/Jcs.1985.Supplement_3.20 |
0.423 |
|
| 1985 |
Zachary I, Rozengurt E. High-affinity receptors for peptides of the bombesin family in Swiss 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 82: 7616-20. PMID 2999772 DOI: 10.1073/Pnas.82.22.7616 |
0.381 |
|
| 1985 |
Sinnett-Smith JW, Rozengurt E. Diacylglycerol treatment rapidly decreases the affinity of the epidermal growth factor receptors of Swiss 3T3 cells. Journal of Cellular Physiology. 124: 81-6. PMID 2995413 DOI: 10.1002/Jcp.1041240114 |
0.465 |
|
| 1985 |
Vara F, Rozengurt E. Stimulation of Na+/H+ antiport activity by epidermal growth factor and insulin occurs without activation of protein kinase C. Biochemical and Biophysical Research Communications. 130: 646-53. PMID 2992479 DOI: 10.1016/0006-291X(85)90466-8 |
0.493 |
|
| 1985 |
Rozengurt E, Sinnett-Smith J, Taylor-Papadimitriou J. Production of PDGF-like growth factor by breast cancer cell lines. International Journal of Cancer. 36: 247-52. PMID 2991148 DOI: 10.1002/Ijc.2910360218 |
0.363 |
|
| 1985 |
O'Neill C, Riddle P, Rozengurt E. Stimulating the proliferation of quiescent 3T3 fibroblasts by peptide growth factors or by agents which elevate cellular cyclic AMP level has opposite effects on motility. Experimental Cell Research. 156: 65-78. PMID 2981176 DOI: 10.1016/0014-4827(85)90262-9 |
0.419 |
|
| 1985 |
Vara F, Schneider JA, Rozengurt E. Ionic responses rapidly elicited by activation of protein kinase C in quiescent Swiss 3T3 cells Proceedings of the National Academy of Sciences of the United States of America. 82: 2384-2388. PMID 2581246 DOI: 10.1073/Pnas.82.8.2384 |
0.441 |
|
| 1985 |
Stroobant P, Gullick W, Waterfield M, Rozengurt E. Highly purified fibroblast-derived growth factor, an SV40-transformed fibroblast-secreted mitogen, is closely related to platelet-derived growth factor. The Embo Journal. 4: 1945-1949. DOI: 10.1002/J.1460-2075.1985.Tb03875.X |
0.382 |
|
| 1985 |
Rodriguez-Pena A, Rozengurt E. Serum, like phorbol esters, rapidly activates protein kinase C in intact quiescent fibroblasts. The Embo Journal. 4: 71-76. DOI: 10.1002/j.1460-2075.1985.tb02319.x |
0.323 |
|
| 1984 |
Burns CP, Rozengurt E. Serum, platelet-derived growth factor, vasopressin and phorbol esters increase intracellular pH in Swiss 3T3 cells. Biochemical and Biophysical Research Communications. 116: 931-8. PMID 6580905 DOI: 10.1016/S0006-291X(83)80231-9 |
0.346 |
|
| 1984 |
Rozengurt E, Collins M. Molecular aspects of growth factor action: receptors and intracellular signals. The Journal of Pathology. 141: 309-31. PMID 6363650 DOI: 10.1002/Path.1711410310 |
0.347 |
|
| 1984 |
Collins MK, Rozengurt E. Insulin induces a selective heterologous desensitization of the mitogenic response of Swiss 3T3 cells to vasopressin. Experimental Cell Research. 151: 396-407. PMID 6323200 DOI: 10.1016/0014-4827(84)90390-2 |
0.351 |
|
| 1984 |
Collins MK, Rozengurt E. Homologous and heterologous mitogenic desensitization of Swiss 3T3 cells to phorbol esters and vasopressin: role of receptor and postreceptor steps. Journal of Cellular Physiology. 118: 133-42. PMID 6319436 DOI: 10.1002/Jcp.1041180205 |
0.445 |
|
| 1984 |
Rozengurt E, Rodriguez-Pena M, Smith KA. Phorbol esters, phospholipase C, and growth factors rapidly stimulate the phosphorylation of a Mr 80,000 protein in intact quiescent 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 80: 7244-8. PMID 6316349 DOI: 10.1073/pnas.80.23.7244 |
0.414 |
|
| 1984 |
Rozengurt E, Rodriguez-Pena A, Coombs M, Sinnett-Smith J. Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 cells: role of Ca2+-sensitive phospholipid-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 81: 5748-52. PMID 6237364 DOI: 10.1073/Pnas.81.18.5748 |
0.543 |
|
| 1984 |
Rodriguez-Pena A, Rozengurt E. Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells. Biochemical and Biophysical Research Communications. 120: 1053-9. PMID 6233972 DOI: 10.1016/S0006-291X(84)80213-2 |
0.486 |
|
| 1984 |
Ebsworth NM, Taylor-Papadimitriou J, Rozengurt E. Cyclic AMP does not mediate inhibition of DNA synthesis by interferon in mouse Swiss 3T3 cells. Journal of Cellular Physiology. 120: 146-50. PMID 6204998 DOI: 10.1002/Jcp.1041200206 |
0.449 |
|
| 1984 |
Lopez-Rivas A, Stroobant P, Waterfield M, Rozengurt E. Ionic responses rapidly elicited by porcine platelet-derived growth factor in Swiss 3T3 cells. The Embo Journal. 3: 939-944. DOI: 10.1002/J.1460-2075.1984.Tb01911.X |
0.419 |
|
| 1983 |
Greenberg PL, Rozengurt E. Role of intracellular degradation of epidermal growth factor in mitogenesis. Experimental Cell Research. 142: 111-7. PMID 6982826 DOI: 10.1016/0014-4827(82)90415-3 |
0.425 |
|
| 1983 |
Lopez-Rivas A, Rozengurt E. Serum rapidly mobilizes calcium from an intracellular pool in quiescent fibroblastic cells. Biochemical and Biophysical Research Communications. 114: 240-7. PMID 6882425 DOI: 10.1016/0006-291X(83)91619-4 |
0.323 |
|
| 1983 |
Rozengurt E, Sinnett-Smith J. Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 80: 2936-40. PMID 6344074 DOI: 10.1073/Pnas.80.10.2936 |
0.426 |
|
| 1983 |
McKay I, Collins M, Taylor-Papadimitriou J, Rozengurt E. An inhibitory effect of tumour promoters on human epithelial cell growth can be dissociated from an effect on junctional communication. Experimental Cell Research. 145: 245-54. PMID 6305686 DOI: 10.1016/0014-4827(83)90003-4 |
0.38 |
|
| 1983 |
Collins MK, Rozengurt E. Vasopressin induces selective desensitization of its mitogenic response in Swiss 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 80: 1924-8. PMID 6300880 DOI: 10.1073/Pnas.80.7.1924 |
0.444 |
|
| 1983 |
Rozengurt E, Courtenay-Luck N. Signalling mitogenesis in 3T3 cells: role of monovalent ion fluxes and cyclic nucleotides. Bioscience Reports. 2: 589-95. PMID 6291663 DOI: 10.1007/Bf01314220 |
0.419 |
|
| 1983 |
Rozengurt E, Collins MK, Keehan M. Mitogenic effect of prostaglandin E1 in Swiss 3T3 cells: role of cyclic AMP. Journal of Cellular Physiology. 116: 379-84. PMID 6193130 DOI: 10.1002/Jcp.1041160316 |
0.451 |
|
| 1983 |
Rozengurt E, Stroobant P, Waterfield MD, Deuel TF, Keehan M. Platelet-derived growth factor elicits cyclic AMP accumulation in Swiss 3T3 cells: role of prostaglandin production. Cell. 34: 265-72. PMID 6192934 DOI: 10.1016/0092-8674(83)90157-5 |
0.426 |
|
| 1983 |
Becker MA, Dicker P, Rozengurt E. Mitogenic enhancement of purine base phosphoribosylation in Swiss mouse 3T3 cells. The American Journal of Physiology. 244: C288-96. PMID 6187219 DOI: 10.1152/Ajpcell.1983.244.3.C288 |
0.395 |
|
| 1982 |
Rozengurt E. Stimulation of Na influx, Na-K pump activity and DNA synthesis in quiescent cultured cells. Advances in Enzyme Regulation. 19: 61-85. PMID 7337035 DOI: 10.1016/0065-2571(81)90009-1 |
0.409 |
|
| 1982 |
Friedkin M, Rozengurt E. The role of cytoplasmic microtubules in the regulation of the activity of peptide growth factors. Advances in Enzyme Regulation. 19: 39-59. PMID 7039258 DOI: 10.1016/0065-2571(81)90008-X |
0.412 |
|
| 1982 |
Schuldiner S, Rozengurt E. Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization. Proceedings of the National Academy of Sciences of the United States of America. 79: 7778-82. PMID 6961450 DOI: 10.1073/Pnas.79.24.7778 |
0.372 |
|
| 1982 |
Collins M, Rozengurt E. Stimulation of DNA synthesis in murine fibroblasts by the tumour promoter teleocidin: relationship to phorbol esters and vasopressin. Biochemical and Biophysical Research Communications. 104: 1159-66. PMID 6803796 DOI: 10.1016/0006-291X(82)91372-9 |
0.453 |
|
| 1982 |
Dicker P, Rozengurt E. Stimulation of DNA synthesis by transient exposure of cell cultures to TPA or polypeptide mitogens: induction of competence or incomplete removal? Journal of Cellular Physiology. 109: 99-109. PMID 6460041 DOI: 10.1002/Jcp.1041090112 |
0.338 |
|
| 1982 |
Rozengurt E. Synergistic stimulation of DNA synthesis by cyclic AMP derivatives and growth factors in mouse 3T3 cells. Journal of Cellular Physiology. 112: 243-50. PMID 6288743 DOI: 10.1002/Jcp.1041120213 |
0.435 |
|
| 1982 |
Collins MK, Rozengurt E. Binding of phorbol esters to high-affinity sites on murine fibroblastic cells elicits a mitogenic response. Journal of Cellular Physiology. 112: 42-50. PMID 6286693 DOI: 10.1002/Jcp.1041120108 |
0.361 |
|
| 1982 |
Rozengurt E. Adenosine receptor activation in quiescent Swiss 3T3 cells. Enhancement of cAMP levels, DNA synthesis and cell division. Experimental Cell Research. 139: 71-8. PMID 6282602 DOI: 10.1016/0014-4827(82)90319-6 |
0.442 |
|
| 1982 |
Becker MA, Rozengurt E. Inorganic phosphate is necessary for the stimulation of DNA synthesis in swiss 3T3 cells by pure mitogenic agents. Experimental Cell Research. 139: 431-6. PMID 6211364 DOI: 10.1016/0014-4827(82)90273-7 |
0.352 |
|
| 1982 |
Paris S, Rozengurt E. Cyclic AMP stimulation of Na-K pump activity in quiescent swiss 3T3 cells. Journal of Cellular Physiology. 112: 273-80. PMID 6181081 DOI: 10.1002/Jcp.1041120217 |
0.378 |
|
| 1982 |
Taylor-Papadimitriou J, Shearer M, Rozengurt E. Inhibitory effect of interferon on cellular DNA synthesis: modulation by pure mitogenic factors. Journal of Interferon Research. 1: 401-9. PMID 6180072 DOI: 10.1089/Jir.1981.1.401 |
0.348 |
|
| 1981 |
Dicker P, Rozengurt E. Tumour promoter induces proliferation of 3T6 cells in serum-free medium, as do polypeptide growth factors. Experimental Cell Research. 130: 474-7. PMID 7449865 DOI: 10.1016/0014-4827(80)90030-0 |
0.364 |
|
| 1981 |
Dicker P, Pohjanpelto P, Pettican P, Rozengurt E. Similarities between fibroblast-derived growth factor and platelet-derived growth factor. Experimental Cell Research. 135: 221-7. PMID 6456922 DOI: 10.1016/0014-4827(81)90314-1 |
0.385 |
|
| 1981 |
Friedkin M, Legg A, Rozengurt E. Enhancement of DNA synthesis by colchicine in 3T3 mouse fibroblasts stimulated with growth factors. Experimental Cell Research. 129: 23-30. PMID 6448749 DOI: 10.1016/0014-4827(80)90327-4 |
0.386 |
|
| 1981 |
Rozengurt E, Legg A, Strang G, Courtenay-Luck N. Cyclic AMP: a mitogenic signal for Swiss 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 4392-6. PMID 6270677 DOI: 10.1073/Pnas.78.7.4392 |
0.445 |
|
| 1981 |
Dicker P, Rozengurt E. Phorbol ester stimulation of Na influx and Na-K pump activity in Swiss 3T3 cells. Biochemical and Biophysical Research Communications. 100: 433-41. PMID 6266407 DOI: 10.1016/S0006-291X(81)80115-5 |
0.345 |
|
| 1981 |
Rozengurt E, Gelehrter TD, Legg A, Pettican P. Melittin stimulates Na entry, Na-K pump activity and DNA synthesis in quiescent cultures of mouse cells. Cell. 23: 781-8. PMID 6261955 DOI: 10.1016/0092-8674(81)90442-6 |
0.423 |
|
| 1981 |
Gelehrter TD, Rozengurt E. Stimulation of monovalent ion fluxes and DNA synthesis in 3T3 cells by melittin and vasopressin is not mediated by phospholipid deacylation. Biochemical and Biophysical Research Communications. 97: 716-24. PMID 6258594 DOI: 10.1016/0006-291X(80)90323-X |
0.366 |
|
| 1981 |
Rozengurt E. Stimulation of DNA synthesis in quiescent cultured cells: exogenous agents, internal signals, and early events. Current Topics in Cellular Regulation. 17: 59-88. PMID 6254731 DOI: 10.1016/B978-0-12-152817-1.50007-9 |
0.397 |
|
| 1981 |
Sreevalsan T, Rozengurt E, Taylor-Papadimitriou J, Burchell J. Differential effect of interferon on DNA synthesis, 2-deoxyglucose uptake and ornithine decarboxylase activity in 3T3 cells stimulated by polypeptide growth factors and tumor promotors. Journal of Cellular Physiology. 104: 1-9. PMID 6160162 DOI: 10.1002/Jcp.1041040102 |
0.409 |
|
| 1980 |
Mendoza SA, Wigglesworth NM, Rozengurt E. Vasopressin rapidly stimulates Na entry and Na-K pump activity in quiescent cultures of mouse 3T3 cells. Journal of Cellular Physiology. 105: 153-62. PMID 7430263 DOI: 10.1002/Jcp.1041050117 |
0.353 |
|
| 1980 |
Dicker P, Heppel LA, Rozengurt E. Control of membrane permeability by external and internal ATP in 3T6 cells grown in serum-free medium Proceedings of the National Academy of Sciences of the United States of America. 77: 2103-2107. PMID 6929541 DOI: 10.1073/Pnas.77.4.2103 |
0.348 |
|
| 1980 |
Mendoza SA, Wigglesworth NM, Pohjanpelto P, Rozengurt E. Na entry and Na-K pump activity in murine, hamster, and human cells--effect of monensin, serum, platelet extract, and viral transformation. Journal of Cellular Physiology. 103: 17-27. PMID 6253505 DOI: 10.1002/Jcp.1041030104 |
0.333 |
|
| 1980 |
Brown KD, Friedkin M, Rozengurt E. Colchicine inhibits epidermal growth factor degradation in 3T3 cells Proceedings of the National Academy of Sciences of the United States of America. 77: 480-484. PMID 6244563 DOI: 10.1073/Pnas.77.1.480 |
0.39 |
|
| 1980 |
Dicker P, Rozengurt E. Synergistic stimulation of early events and DNA synthesis by phorbol esters, polypeptide growth factors, and retinoids in cultured fibroblasts. Journal of Supramolecular Structure. 11: 79-93. PMID 522485 DOI: 10.1002/Jss.400110109 |
0.433 |
|
| 1980 |
Dicker P, Rozengurt E. Retinoids enhance mitogenesis by tumour promotor and polypeptide growth factors. Biochemical and Biophysical Research Communications. 91: 1203-10. PMID 316701 DOI: 10.1016/0006-291X(79)91195-1 |
0.381 |
|
| 1979 |
Smith JB, Rozengurt E. Lithium transport by fibroblastic mouse cells: characterization and stimulation by serum and growth factors in quiescent cultures. Journal of Cellular Physiology. 97: 441-9. PMID 730779 DOI: 10.1002/Jcp.1040970319 |
0.365 |
|
| 1979 |
Sreevalsan T, Taylor-Papadimitriou J, Rozengurt E. Selective inhibition by interferon of serum-stimulated biochemical events in 3T3 cells. Biochemical and Biophysical Research Communications. 87: 679-85. PMID 454417 DOI: 10.1016/0006-291X(79)92012-6 |
0.417 |
|
| 1979 |
Taylor-Papadimitriou J, Rozengurt E. The role of thymidine uptake in the control of cell proliferation. Experimental Cell Research. 119: 393-6. PMID 428467 DOI: 10.1016/0014-4827(79)90369-0 |
0.418 |
|
| 1979 |
Friedkin M, Legg A, Rozengurt E. Antitubulin agents enhance the stimulation of DNA synthesis by polypeptide growth factors in 3T3 mouse fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 76: 3909-12. PMID 315067 DOI: 10.1073/Pnas.76.8.3909 |
0.376 |
|
| 1979 |
Rozengurt E, Legg A, Pettican P. Vasopressin stimulation of mouse 3T3 cell growth. Proceedings of the National Academy of Sciences of the United States of America. 76: 1284-7. PMID 312501 DOI: 10.1073/Pnas.76.3.1284 |
0.408 |
|
| 1979 |
Brown KD, Dicker P, Rozengurt E. Inhibition of epidermal growth factor binding to surface receptors by tumor promotors Biochemical and Biophysical Research Communications. 86: 1037-1043. PMID 312103 DOI: 10.1016/0006-291X(79)90221-3 |
0.389 |
|
| 1979 |
Dicker P, Rozengurt E. Stimulation of DNA synthesis by tumour promoter and pure mitogenic factors. Nature. 276: 723-6. PMID 310518 DOI: 10.1038/276723A0 |
0.393 |
|
| 1978 |
Rozengurt E, Mierzejewski K, Wigglesworth N. Uridine transport and phosphorylation in mouse cells in culture: effect of growth-promoting factors, cell cycle transit and oncogenic transformation. Journal of Cellular Physiology. 97: 241-51. PMID 701389 DOI: 10.1002/Jcp.1040970213 |
0.454 |
|
| 1978 |
Mierzejewski K, Rozengurt E. A partially purified serum fraction synergistically enhances the mitogenic activity of epidermal growth factor and insulin in quiescent cultures of 3T3 cells. Biochemical and Biophysical Research Communications. 83: 874-80. PMID 309333 DOI: 10.1016/0006-291X(78)91476-6 |
0.375 |
|
| 1977 |
Mierzejewski K, Rozengurt E. Stimulation of DNA synthesis and cell division in a chemically defined medium: effect of epidermal growth factor, insulin and vitamin B12 on resting cultures of 3T6 cells. Biochemical and Biophysical Research Communications. 73: 271-8. PMID 999711 DOI: 10.1016/0006-291X(76)90703-8 |
0.408 |
|
| 1977 |
Rozengurt E, Stein WD, Wigglesworth NM. Uptake of nucleosides in density-inhibited cultures of 3T3 cells [25] Nature. 267: 442-444. PMID 876360 DOI: 10.1038/267442A0 |
0.468 |
|
| 1977 |
Rozengurt E, Stein WD. Regulation of uridine uptake by serum and insulin in density-inhibited 3T3 cells Bba - Biomembranes. 464: 417-432. PMID 831802 DOI: 10.1016/0005-2736(77)90015-3 |
0.335 |
|
| 1977 |
Mierzejewski K, Rozengurt E. Vitamin B12 enhances the stimulation of DNA synthesis by serum in resting cultures of 3T6 cells. Experimental Cell Research. 106: 394-7. PMID 558888 DOI: 10.1016/0014-4827(77)90187-2 |
0.317 |
|
| 1977 |
Mierzejewski K, Rozengurt E. Density-dependent inhibition of fibroblast growth is overcome by pure mitogenic factors. Nature. 269: 155-6. PMID 302916 DOI: 10.1038/269155A0 |
0.403 |
|
| 1977 |
Rozengurt E, Schneider JA, Diamond I, Legg A. The high rate of aerobic glycolysis of transformed 3T3 cells persists after cell homogenization. Biochemical and Biophysical Research Communications. 78: 83-90. PMID 199175 DOI: 10.1016/0006-291X(77)91224-4 |
0.336 |
|
| 1976 |
Rozengurt E, Po CC. Selective cytotoxicity for transformed 3T3 cells. Nature. 261: 701-2. PMID 180420 DOI: 10.1038/261701A0 |
0.365 |
|
| 1975 |
Jimenez de Asua L, Rozengurt E. Multiple control mechanisms underlie initiation of growth in animal cells. Nature. 251: 624-6. PMID 4371147 DOI: 10.1038/251624A0 |
0.402 |
|
| 1975 |
Brownstein BL, Rozengurt E, Jimenez de Asua L, Stoker M. Dissociation by cytochalasin B of movement, DNA synthesis and transport in 3T3 cells. Journal of Cellular Physiology. 85: 579-85. PMID 1170181 DOI: 10.1002/Jcp.1040850309 |
0.338 |
|
| 1975 |
Rozengurt E, Heppel LA. Serum rapidly stimulates ouabain sensitive 86Rb+ influx in quiescent 3T3 cells Proceedings of the National Academy of Sciences of the United States of America. 72: 4492-4495. PMID 1060129 DOI: 10.1073/Pnas.72.11.4492 |
0.368 |
|
| 1975 |
Epstein CJ, de Asua LJ, Rozengurt E. The role of cyclic AMP in myogenesis. Journal of Cellular Physiology. 86: 83-90. PMID 170293 DOI: 10.1002/Jcp.1040860110 |
0.356 |
|
| 1975 |
Rozengurt E, Heppel LA. A specific effect of external ATP on the permeability of transformed 3T3 cells Biochemical and Biophysical Research Communications. 67: 1581-1588. PMID 1039 DOI: 10.1016/0006-291X(75)90207-7 |
0.341 |
|
| 1974 |
de Asua LJ, Rozengurt E, Dulbecco R. Kinetics of early changes in phosphate and uridine transport and cyclic AMP levels stimulated by serum in density-inhibited 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 71: 96-8. PMID 4359335 DOI: 10.1073/Pnas.71.1.96 |
0.317 |
|
| 1969 |
Jimenez de Asua L, Rozengurt E, Carminatti H. Estradiol induction of pyruvate kinase in the rat uterus. Biochimica Et Biophysica Acta. 170: 254-62. PMID 5751124 DOI: 10.1016/0304-4165(68)90005-6 |
0.406 |
|
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