| Year |
Citation |
Score |
| 2022 |
Wu H, Tang X, Wang Y, Wang N, Chen Q, Xie J, Liu S, Zhong Z, Qiu Y, Situ P, Zern MA, Wang J, Chen H, Duan Y. Dextran sulfate prevents excess aggregation of human pluripotent stem cells in 3D culture by inhibiting ICAM1 expression coupled with down-regulating E-cadherin through activating the Wnt signaling pathway. Stem Cell Research & Therapy. 13: 218. PMID 35619172 DOI: 10.1186/s13287-022-02890-4 |
0.312 |
|
| 2021 |
Wang N, Li X, Zhong Z, Qiu Y, Liu S, Wu H, Tang X, Chen C, Fu Y, Chen Q, Guo T, Li J, Zhang S, Zern MA, Ma K, et al. 3D hESC exosomes enriched with miR-6766-3p ameliorates liver fibrosis by attenuating activated stellate cells through targeting the TGFβRII-SMADS pathway. Journal of Nanobiotechnology. 19: 437. PMID 34930304 DOI: 10.1186/s12951-021-01138-2 |
0.43 |
|
| 2021 |
Tang X, Wu H, Xie J, Wang N, Chen Q, Zhong Z, Qiu Y, Wang J, Li X, Situ P, Lai L, Zern MA, Chen H, Duan Y. The combination of dextran sulphate and polyvinyl alcohol prevents excess aggregation and promotes proliferation of pluripotent stem cells in suspension culture. Cell Proliferation. e13112. PMID 34390064 DOI: 10.1111/cpr.13112 |
0.32 |
|
| 2017 |
Chen J, Tschudy-Seney B, Ma X, Zern MA, Liu P, Duan Y. Salvianolic acid B enhances hepatic differentiation of human Embryonic Stem cells via upregulation of WNT pathway and inhibition of Notch pathway. Stem Cells and Development. PMID 29256825 DOI: 10.1089/scd.2017.0168 |
0.408 |
|
| 2017 |
Chen J, Chen L, Zern MA, Theise ND, Diehl AM, Liu P, Duan Y. The diversity and plasticity of adult hepatic progenitor cells and their niche. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 28135758 DOI: 10.1111/liv.13377 |
0.44 |
|
| 2016 |
Chen J, Gao W, Zhou P, Ma X, Tschudy-Seney B, Liu C, Zern MA, Liu P, Duan Y. Enhancement of hepatocyte differentiation from human embryonic stem cells by Chinese medicine Fuzhenghuayu. Scientific Reports. 6: 18841. PMID 26733102 DOI: 10.1038/srep18841 |
0.498 |
|
| 2015 |
Zhang X, Du G, Xu Y, Li X, Fan W, Chen J, Liu C, Chen G, Liu C, Zern MA, Mu Y, Liu P. Inhibition of notch signaling pathway prevents cholestatic liver fibrosis by decreasing the differentiation of hepatic progenitor cells into cholangiocytes. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 26692291 DOI: 10.1038/labinvest.2015.149 |
0.37 |
|
| 2015 |
Chen J, Zhang X, Xu Y, Li X, Ren S, Zhou Y, Duan Y, Zern M, Zhang H, Chen G, Liu C, Mu Y, Liu P. Hepatic Progenitor Cells Contribute to the Progression of 2-Acetylaminofluorene/Carbon Tetrachloride-Induced Cirrhosis via the Non-Canonical Wnt Pathway. Plos One. 10: e0130310. PMID 26087010 DOI: 10.1371/journal.pone.0130310 |
0.385 |
|
| 2015 |
Fan YH, Ding J, Nguyen S, Liu XJ, Xu G, Zhou HY, Duan NN, Yang SM, Zern MA, Wu J. Aberrant hedgehog signaling is responsible for the highly invasive behavior of a subpopulation of hepatoma cells. Oncogene. PMID 25772244 DOI: 10.1038/Onc.2015.67 |
0.304 |
|
| 2014 |
Gao W, Zhou P, Ma X, Tschudy-Seney B, Chen J, Magner NL, Revzin A, Nolta JA, Zern MA, Duan Y. Ethanol negatively regulates hepatic differentiation of hESC by inhibition of the MAPK/ERK signaling pathway in vitro. Plos One. 9: e112698. PMID 25393427 DOI: 10.1371/Journal.Pone.0112698 |
0.358 |
|
| 2014 |
Eun JR, Jung YJ, Zhang Y, Zhang Y, Tschudy-Seney B, Ramsamooj R, Wan YJ, Theise ND, Zern MA, Duan Y. Hepatoma SK Hep-1 cells exhibit characteristics of oncogenic mesenchymal stem cells with highly metastatic capacity. Plos One. 9: e110744. PMID 25338121 DOI: 10.1371/journal.pone.0110744 |
0.469 |
|
| 2014 |
Ghaedi M, Duan Y, Zern MA, Revzin A. Hepatic differentiation of human embryonic stem cells on growth factor-containing surfaces. Journal of Tissue Engineering and Regenerative Medicine. 8: 886-95. PMID 23086797 DOI: 10.1002/Term.1595 |
0.446 |
|
| 2013 |
Magner NL, Jung Y, Wu J, Nolta JA, Zern MA, Zhou P. Insulin and IGFs enhance hepatocyte differentiation from human embryonic stem cells via the PI3K/AKT pathway. Stem Cells (Dayton, Ohio). 31: 2095-103. PMID 23836547 DOI: 10.1002/Stem.1478 |
0.353 |
|
| 2013 |
Ma X, Duan Y, Tschudy-Seney B, Roll G, Behbahan IS, Ahuja TP, Tolstikov V, Wang C, McGee J, Khoobyari S, Nolta JA, Willenbring H, Zern MA. Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells. Stem Cells Translational Medicine. 2: 409-19. PMID 23681950 DOI: 10.5966/Sctm.2012-0160 |
0.391 |
|
| 2012 |
Jung CJ, Iyengar S, Blahnik KR, Jiang JX, Tahimic C, Torok NJ, de vere White RW, Farnham PJ, Zern M. Human ESC self-renewal promoting microRNAs induce epithelial-mesenchymal transition in hepatocytes by controlling the PTEN and TGFβ tumor suppressor signaling pathways. Molecular Cancer Research : McR. 10: 979-91. PMID 22622027 DOI: 10.1158/1541-7786.Mcr-11-0421 |
0.601 |
|
| 2011 |
Jung CJ, Iyengar S, Blahnik KR, Ajuha TP, Jiang JX, Farnham PJ, Zern M. Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation. Plos One. 6: e27740. PMID 22140464 DOI: 10.1371/Journal.Pone.0027740 |
0.592 |
|
| 2011 |
Ghaedi M, Tuleuova N, Zern MA, Wu J, Revzin A. Bottom-up signaling from HGF-containing surfaces promotes hepatic differentiation of mesenchymal stem cells. Biochemical and Biophysical Research Communications. 407: 295-300. PMID 21382341 DOI: 10.1016/J.Bbrc.2011.03.005 |
0.407 |
|
| 2011 |
Behbahan IS, Duan Y, Lam A, Khoobyari S, Ma X, Ahuja TP, Zern MA. New approaches in the differentiation of human embryonic stem cells and induced pluripotent stem cells toward hepatocytes. Stem Cell Reviews. 7: 748-59. PMID 21336836 DOI: 10.1007/s12015-010-9216-4 |
0.399 |
|
| 2011 |
Chen X, Lingala S, Khoobyari S, Nolta J, Zern MA, Wu J. Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations. Journal of Hepatology. 55: 838-45. PMID 21334406 DOI: 10.1016/J.Jhep.2010.12.043 |
0.328 |
|
| 2010 |
Tuleuova N, Lee JY, Lee J, Ramanculov E, Zern MA, Revzin A. Using growth factor arrays and micropatterned co-cultures to induce hepatic differentiation of embryonic stem cells. Biomaterials. 31: 9221-31. PMID 20832855 DOI: 10.1016/J.Biomaterials.2010.08.050 |
0.439 |
|
| 2010 |
Lingala S, Cui YY, Chen X, Ruebner BH, Qian XF, Zern MA, Wu J. Immunohistochemical staining of cancer stem cell markers in hepatocellular carcinoma. Experimental and Molecular Pathology. 89: 27-35. PMID 20511115 DOI: 10.1016/J.Yexmp.2010.05.005 |
0.322 |
|
| 2010 |
Duan Y, Ma X, Ma X, Zou W, Wang C, Bahbahan IS, Ahuja TP, Tolstikov V, Zern MA. Differentiation and characterization of metabolically functioning hepatocytes from human embryonic stem cells. Stem Cells (Dayton, Ohio). 28: 674-86. PMID 20135682 DOI: 10.1002/stem.315 |
0.371 |
|
| 2010 |
Yoon S, Kim TH, Natarajan A, Wang SS, Choi J, Wu J, Zern MA, Venugopal SK. Acute liver injury upregulates microRNA-491-5p in mice, and its overexpression sensitizes Hep G2 cells for tumour necrosis factor-alpha-induced apoptosis. Liver International : Official Journal of the International Association For the Study of the Liver. 30: 376-87. PMID 20015148 DOI: 10.1111/J.1478-3231.2009.02181.X |
0.309 |
|
| 2009 |
Lee JY, Tuleuova N, Jones CN, Ramanculov E, Zern MA, Revzin A. Directing hepatic differentiation of embryonic stem cells with protein microarray-based co-cultures. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 460-8. PMID 20023756 DOI: 10.1039/B905757A |
0.466 |
|
| 2009 |
Jones CN, Tuleuova N, Lee JY, Ramanculov E, Reddi AH, Zern MA, Revzin A. Cultivating liver cells on printed arrays of hepatocyte growth factor. Biomaterials. 30: 3733-41. PMID 19375794 DOI: 10.1016/J.Biomaterials.2009.03.039 |
0.311 |
|
| 2008 |
Choi MS, Catana AM, Wu J, Kim YS, Yoon SJ, Borowsky AD, Gambhir SS, Gupta S, Zern MA. Use of bioluminescent imaging to assay the transplantation of immortalized human fetal hepatocytes into mice. Cell Transplantation. 17: 899-909. PMID 19069633 DOI: 10.3727/096368908786576471 |
0.304 |
|
| 2008 |
Ma X, Duan Y, Jung CJ, Wu J, VandeVoort CA, Zern MA. The differentiation of hepatocyte-like cells from monkey embryonic stem cells. Cloning and Stem Cells. 10: 485-93. PMID 18795869 DOI: 10.1089/Clo.2007.0012 |
0.592 |
|
| 2008 |
Jones CN, Lee JY, Zhu J, Stybayeva G, Ramanculov E, Zern MA, Revzin A. Multifunctional protein microarrays for cultivation of cells and immunodetection of secreted cellular products. Analytical Chemistry. 80: 6351-7. PMID 18642875 DOI: 10.1021/Ac8007626 |
0.312 |
|
| 2007 |
Venugopal SK, Wu J, Catana AM, Eisenbud L, He SQ, Duan YY, Follenzi A, Zern MA. Lentivirus-mediated superoxide dismutase1 gene delivery protects against oxidative stress-induced liver injury in mice. Liver International : Official Journal of the International Association For the Study of the Liver. 27: 1311-22. PMID 18036097 DOI: 10.1111/J.1478-3231.2007.01612.X |
0.306 |
|
| 2007 |
Duan Y, Catana A, Meng Y, Yamamoto N, He S, Gupta S, Gambhir SS, Zern MA. Differentiation and enrichment of hepatocyte-like cells from human embryonic stem cells in vitro and in vivo. Stem Cells (Dayton, Ohio). 25: 3058-68. PMID 17885076 DOI: 10.1634/Stemcells.2007-0291 |
0.474 |
|
| 2006 |
Lee JY, Jones C, Zern MA, Revzin A. Analysis of local tissue-specific gene expression in cellular micropatterns. Analytical Chemistry. 78: 8305-12. PMID 17165820 DOI: 10.1021/Ac0613333 |
0.417 |
|
| 2006 |
Zhan SS, Jiang JX, Wu J, Halsted C, Friedman SL, Zern MA, Torok NJ. Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo. Hepatology (Baltimore, Md.). 43: 435-43. PMID 16496318 DOI: 10.1002/Hep.21093 |
0.348 |
|
| 2005 |
Torok N, Wu J, Zern M, Halsted C, French S, Friedman S, Zhan S. Phagocytosis of Apoptotic Bodies by Hepatic Stellate Cells Occurs in Vivo and Is an Important Mechanism in Liver Fibrogenesis Gastroenterology. 129: 1110. DOI: 10.1053/J.Gastro.2005.08.010 |
0.432 |
|
| 2004 |
Shirahashi H, Wu J, Yamamoto N, Catana A, Wege H, Wager B, Okita K, Zern MA. Differentiation of human and mouse embryonic stem cells along a hepatocyte lineage. Cell Transplantation. 13: 197-211. PMID 15191158 DOI: 10.3727/000000004783984016 |
0.451 |
|
| 2003 |
Wege H, Chui MS, Le HT, Strom SC, Zern MA. In vitro expansion of human hepatocytes is restricted by telomere-dependent replicative aging. Cell Transplantation. 12: 897-906. PMID 14763510 |
0.379 |
|
| 2003 |
Zalzman M, Gupta S, Giri RK, Berkovich I, Sappal BS, Karnieli O, Zern MA, Fleischer N, Efrat S. Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 7253-8. PMID 12756298 DOI: 10.1073/pnas.1136854100 |
0.342 |
|
| 2003 |
Wege H, Le HT, Chui MS, Liu L, Wu J, Giri R, Malhi H, Sappal BS, Kumaran V, Gupta S, Zern MA. Telomerase reconstitution immortalizes human fetal hepatocytes without disrupting their differentiation potential. Gastroenterology. 124: 432-44. PMID 12557149 DOI: 10.1053/Gast.2003.50064 |
0.451 |
|
| 2001 |
Wu J, Zern MA. Hepatic stellate cells: a target for the treatment of liver fibrosis. Journal of Gastroenterology. 35: 665-72. PMID 11023037 DOI: 10.1007/S005350070045 |
0.312 |
|
| 1999 |
Zhu J, Wu J, Frizell E, Liu SL, Bashey R, Rubin R, Norton P, Zern MA. Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis. Gastroenterology. 117: 1198-204. PMID 10535884 DOI: 10.1016/S0016-5085(99)70406-3 |
0.302 |
|
| 1997 |
Mirza A, Liu SL, Frizell E, Zhu J, Maddukuri S, Martinez J, Davies P, Schwarting R, Norton P, Zern MA. A role for tissue transglutaminase in hepatic injury and fibrogenesis, and its regulation by NF-kappaB. The American Journal of Physiology. 272: G281-8. PMID 9124352 DOI: 10.1152/ajpgi.1997.272.2.G281 |
0.311 |
|
| 1995 |
Frizell E, Liu S, Abraham A, Ozaki I, Eghbali M, Sage EH, Zern MA. Expression of SPARC in normal and fibrotic livers Hepatology. 21: 847-854. DOI: 10.1002/Hep.1840210335 |
0.369 |
|
| 1993 |
Weiner FR, Esposti SD, Zern MA. A role for cytokines as regulators of hepatic fibrogenesis. Gastroenterologia Japonica. 97-101; discussion 1. PMID 8486236 DOI: 10.1007/BF02782899 |
0.312 |
|
| 1992 |
Weiner FR, Shah A, Biempica L, Zern MA, Czaja MJ. The effects of hepatic fibrosis on Ito cell gene expression. Matrix (Stuttgart, Germany). 12: 36-43. PMID 1560788 DOI: 10.1016/S0934-8832(11)80102-2 |
0.38 |
|
| 1990 |
Weiner FR, Giambrone MA, Czaja MJ, Shah A, Annoni G, Takahashi S, Eghbali M, Zern MA. Ito-cell gene expression and collagen regulation. Hepatology (Baltimore, Md.). 11: 111-7. PMID 2295461 DOI: 10.1002/hep.1840110119 |
0.32 |
|
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