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Sergey A. Kozmin - Publications

Affiliations: 
Chemistry University of Chicago, Chicago, IL 
Area:
Chemical Biology - Natural Products - Drug Discovery
Website:
http://chemistry.uchicago.edu/faculty/faculty/person/member/sergey-a-kozmin.html
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69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Efimova EV, Takahashi S, Shamsi NA, Wu D, Labay E, Ulanovskaya OA, Weichselbaum RR, Kozmin SA, Kron SJ. Linking Cancer Metabolism to DNA Repair and Accelerated Senescence. Molecular Cancer Research : McR. PMID 26538285 DOI: 10.1158/1541-7786.Mcr-15-0263  0.722
2015 Takeuchi T, Schumacker PT, Kozmin SA. Identification of fumarate hydratase inhibitors with nutrient-dependent cytotoxicity. Journal of the American Chemical Society. 137: 564-7. PMID 25469852 DOI: 10.1021/Ja5101257  0.327
2013 Cabrera-Pardo JR, Chai DI, Kozmin SA. Silver-Promoted Benzannulations of Siloxy Alkynes with Pyridinium and Isoquinolinium Salts. Advanced Synthesis & Catalysis. 355: 2495-2498. PMID 24653670 DOI: 10.1002/Adsc.201300443  0.446
2013 Montavon TJ, Türkmen YE, Shamsi NA, Miller C, Sumaria CS, Rawal VH, Kozmin SA. [2+2+2] Cycloadditions of siloxy alkynes with 1,2-diazines: from reaction discovery to identification of an antiglycolytic chemotype. Angewandte Chemie (International Ed. in English). 52: 13576-9. PMID 24346942 DOI: 10.1002/Anie.201305711  0.799
2013 Liu S, Scotti JS, Kozmin SA. Emulating the logic of monoterpenoid alkaloid biogenesis to access a skeletally diverse chemical library. The Journal of Organic Chemistry. 78: 8645-54. PMID 23937288 DOI: 10.1021/Jo401262V  0.518
2013 Cabrera-Pardo JR, Chai DI, Liu S, Mrksich M, Kozmin SA. Label-assisted mass spectrometry for the acceleration of reaction discovery and optimization. Nature Chemistry. 5: 423-7. PMID 23609094 DOI: 10.1038/Nchem.1612  0.488
2012 Cui J, Chai DI, Miller C, Hao J, Thomas C, Wang J, Scheidt KA, Kozmin SA. Assembly of four diverse heterocyclic libraries enabled by Prins cyclization, Au-catalyzed enyne cycloisomerization, and automated amide synthesis. The Journal of Organic Chemistry. 77: 7435-70. PMID 22860634 DOI: 10.1021/Jo301061R  0.612
2012 Türkmen YE, Montavon TJ, Kozmin SA, Rawal VH. Silver-catalyzed formal inverse electron-demand Diels-Alder reaction of 1,2-diazines and siloxy alkynes. Journal of the American Chemical Society. 134: 9062-5. PMID 22607029 DOI: 10.1021/Ja302537J  0.789
2012 Montavon TJ, Li J, Cabrera-Pardo JR, Mrksich M, Kozmin SA. Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayers. Nature Chemistry. 4: 45-51. PMID 22169871 DOI: 10.1038/Nchem.1212  0.394
2012 Efimova EV, Labay E, Mauceri HJ, Darga TE, Ulanovskaya OA, Kozmin SA, Weichselbaum RR, Kron SJ. Abstract LB-162: DNA-damage foci persistence and accelerated senescence as determinants of radiosensitization by glycolysis inhibitors Molecular and Cellular Biology. DOI: 10.1158/1538-7445.Am2012-Lb-162  0.71
2012 Rawal VH, Kozmin SA. ChemInform Abstract: Introduction to the Synthesis of 1,3-Dienes Cheminform. 43: no-no. DOI: 10.1002/chin.201222225  0.608
2011 Pronin SV, Martinez A, Kuznedelov K, Severinov K, Shuman HA, Kozmin SA. Chemical synthesis enables biochemical and antibacterial evaluation of streptolydigin antibiotics. Journal of the American Chemical Society. 133: 12172-84. PMID 21714556 DOI: 10.1021/Ja2041964  0.657
2011 Cui J, Hao J, Ulanovskaya OA, Dundas J, Liang J, Kozmin SA. Creation and manipulation of common functional groups en route to a skeletally diverse chemical library. Proceedings of the National Academy of Sciences of the United States of America. 108: 6763-8. PMID 21383124 DOI: 10.1073/Pnas.1015253108  0.775
2011 Ulanovskaya OA, Cui J, Kron SJ, Kozmin SA. A pairwise chemical genetic screen identifies new inhibitors of glucose transport. Chemistry & Biology. 18: 222-30. PMID 21338919 DOI: 10.1016/J.Chembiol.2010.12.015  0.764
2011 Pronin SV, Kozmin SA. Synthesis of Streptolydigin Synfacts. 2011: 246-246. DOI: 10.1055/S-0030-1259408  0.682
2011 Shubinets V, Schramm MP, Kozmin SA. Preparation and [2+2] Cycloaddition of 1‐Triisopropylsiloxy‐1‐Hexyne with Methyl Crotonate: 3‐Butyl‐4‐Methyl‐2‐Triisopropylsiloxy‐Cyclobut‐2‐Enecarboxylic Acid Methyl Ester Organic Syntheses. 253-262. DOI: 10.1002/0471264229.Os087.28  0.642
2010 Sun J, Keller VA, Meyer ST, Kozmin SA. Silver-Catalyzed Aldehyde Olefination Using Siloxy Alkynes. Advanced Synthesis & Catalysis. 352. PMID 24273478 DOI: 10.1002/Adsc.200900835  0.642
2010 Pronin SV, Kozmin SA. Synthesis of streptolydigin, a potent bacterial RNA polymerase inhibitor. Journal of the American Chemical Society. 132: 14394-6. PMID 20879772 DOI: 10.1021/Ja107190W  0.673
2010 Cui J, Matsumoto K, Wang CY, Peter ME, Kozmin SA. Synthesis of a high-purity chemical library reveals a potent inducer of oxidative stress. Chembiochem : a European Journal of Chemical Biology. 11: 1224-7. PMID 20461745 DOI: 10.1002/Cbic.201000193  0.51
2010 Rizvi SA, Liu S, Chen Z, Skau C, Pytynia M, Kovar DR, Chmura SJ, Kozmin SA. Rationally simplified bistramide analog reversibly targets actin polymerization and inhibits cancer progression in vitro and in vivo. Journal of the American Chemical Society. 132: 7288-90. PMID 20455580 DOI: 10.1021/Ja101811X  0.564
2010 Lee H, Suzuki M, Cui J, Kozmin SA. Synthesis of an azide-tagged library of 2,3-dihydro-4-quinolones. The Journal of Organic Chemistry. 75: 1756-9. PMID 20141224 DOI: 10.1021/Jo9025447  0.556
2010 Kozmin SA, Janey JM, Rawal VH. ChemInform Abstract: 1-Amino-3-siloxy-1,3-butadienes: Highly Reactive Dienes for the Diels-Alder Reaction. Cheminform. 30: no-no. DOI: 10.1002/chin.199939041  0.607
2010 Shubinets V, Schramm MP, Kozmin SA, Briones JFB, Davies HML. Preparation and [2+2] cycloaddition of 1-triisopropylsiloxy-1-hexyne with methyl crotonate: 3-Butyl-4-methyl-2-triisopropylsiloxy-cyclobut-2-enecarboxylic acid methyl ester Organic Syntheses. 87: 253-262.  0.591
2009 Rizvi SA, Neidt EM, Cui J, Feiger Z, Skau CT, Gardel ML, Kozmin SA, Kovar DR. Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly. Chemistry & Biology. 16: 1158-68. PMID 19942139 DOI: 10.1016/J.Chembiol.2009.10.006  0.605
2008 Ulanovskaya OA, Janjic J, Suzuki M, Sabharwal SS, Schumacker PT, Kron SJ, Kozmin SA. Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide. Nature Chemical Biology. 4: 418-24. PMID 18516048 DOI: 10.1038/Nchembio.94  0.753
2008 Rizvi SA, Courson DS, Keller VA, Rock RS, Kozmin SA. The dual mode of action of bistramide A entails severing of filamentous actin and covalent protein modification. Proceedings of the National Academy of Sciences of the United States of America. 105: 4088-92. PMID 18334642 DOI: 10.1073/Pnas.0710727105  0.694
2008 Matsumoto K, Kozmin SA. ChemInform Abstract: Eight-Step Synthesis of Routiennocin. Cheminform. 39. DOI: 10.1002/chin.200827203  0.309
2008 Matsumoto K, Kozmin S. Eight-Step Synthesis of Routiennocin Advanced Synthesis & Catalysis. 350: 557-560. DOI: 10.1002/Adsc.200700537  0.412
2007 Marjanovic J, Kozmin SA. Spirofungin A: stereoselective synthesis and inhibition of isoleucyl-tRNA synthetase. Angewandte Chemie (International Ed. in English). 46: 8854-7. PMID 17929337 DOI: 10.1002/Anie.200702440  0.734
2006 Sun J, Conley MP, Zhang L, Kozmin SA. Au- and pt-catalyzed cycloisomerizations of 1,5-enynes to cyclohexadienes with a broad alkyne scope. Journal of the American Chemical Society. 128: 9705-10. PMID 16866525 DOI: 10.1021/Ja063384N  0.633
2006 Sun J, Kozmin SA. Silver-catalyzed hydroamination of siloxy alkynes. Angewandte Chemie (International Ed. in English). 45: 4991-3. PMID 16810653 DOI: 10.1002/Anie.200601276  0.579
2006 Rizvi SA, Tereshko V, Kossiakoff AA, Kozmin SA. Structure of bistramide A-actin complex at a 1.35 angstroms resolution. Journal of the American Chemical Society. 128: 3882-3. PMID 16551075 DOI: 10.1021/Ja058319C  0.495
2006 Zhang L, Sun J, Kozmin SA. Brønsted acid-promoted cyclizations of siloxy alkynes with unactivated arenes, alkenes, and alkynes Tetrahedron. 62: 11371-11380. DOI: 10.1016/J.Tet.2006.06.037  0.597
2006 Zhang L, Sun J, Kozmin SA. Gold and platinum catalysis of enyne cycloisomerization Advanced Synthesis and Catalysis. 348: 2271-2296. DOI: 10.1002/Adsc.200600368  0.559
2005 Sun J, Kozmin SA. Brønsted acid-promoted cyclizations of 1-siloxy-1,5-diynes. Journal of the American Chemical Society. 127: 13512-3. PMID 16190711 DOI: 10.1021/Ja055054T  0.584
2005 Zhang L, Kozmin SA. Gold-catalyzed assembly of heterobicyclic systems. Journal of the American Chemical Society. 127: 6962-3. PMID 15884934 DOI: 10.1021/Ja051110E  0.47
2005 Wang Y, Janjic J, Kozmin SA. Synthesis of leucascandrolide A Pure and Applied Chemistry. 77: 1161-1169. DOI: 10.1351/Pac200577071161  0.396
2004 Zhang L, Kozmin SA. Gold-catalyzed cycloisomerization of siloxy enynes to cyclohexadienes. Journal of the American Chemical Society. 126: 11806-7. PMID 15382911 DOI: 10.1021/Ja046112Y  0.458
2004 Zhang L, Kozmin SA. Brønsted acid-promoted cyclizations of siloxyalkynes with arenes and alkenes. Journal of the American Chemical Society. 126: 10204-5. PMID 15315407 DOI: 10.1021/Ja046586X  0.456
2004 Statsuk AV, Liu D, Kozmin SA. Synthesis of bistramide A. Journal of the American Chemical Society. 126: 9546-7. PMID 15291551 DOI: 10.1021/Ja046588H  0.401
2004 Reddy DS, Kozmin SA. Efficient and general approach to eremophilanes using siloxyalkyne-alkene metathesis. The Journal of Organic Chemistry. 69: 4860-2. PMID 15230618 DOI: 10.1021/Jo049431G  0.578
2004 Sweis RF, Schramm MP, Kozmin SA. Silver-catalyzed [2 + 2] cycloadditions of siloxy alkynes. Journal of the American Chemical Society. 126: 7442-3. PMID 15198582 DOI: 10.1021/Ja048251L  0.718
2004 Kozmin SA, Liu D. Chapter 3 Breaking the symmetry of silacyclic templates to assemble pinolidoxin and herbarumin I Strategies and Tactics in Organic Synthesis. 5: 89-110. DOI: 10.1016/S1874-6004(04)80026-1  0.412
2003 Kozmin SA, Wang Y. A three-dimensional array for multiparallel synthesis. Angewandte Chemie (International Ed. in English). 42: 903-5. PMID 12596172 DOI: 10.1002/Anie.200390238  0.318
2003 Kozmin SA, He S, Rawal VH. [4 + 2] Cycloaddition of 1‐Dimethylamino‐3‐tert‐Butyldimethylsiloxy‐1,3‐Butadiene with Methyl Acrylate: 4‐Hydroxymethyl‐2‐Cyclohexen‐1‐One Organic Syntheses. 160-160. DOI: 10.1002/0471264180.Os078.18  0.704
2003 Kozmin SA, He S, Rawal VH. Preparation of (E)‐1‐Dimethylamino‐3‐tert‐Butyldimethylsiloxy‐1,3‐Butadiene Organic Syntheses. 152-152. DOI: 10.1002/0471264180.Os078.17  0.669
2002 Smith AB, Pitram SM, Gaunt MJ, Kozmin SA. Dithiane additions to vinyl epoxides: steric control over the SN2 and SN2' manifolds. Journal of the American Chemical Society. 124: 14516-7. PMID 12465944 DOI: 10.1021/Ja0283100  0.774
2002 Wang Y, Janjic J, Kozmin SA. Synthesis of leucascandrolide A via a spontaneous macrolactolization. Journal of the American Chemical Society. 124: 13670-1. PMID 12431085 DOI: 10.1021/Ja028428G  0.396
2002 Liu D, Kozmin SA. Synthesis of (-)-pinolidoxin: divergent synthetic strategy exploiting a common silacyclic precursor. Organic Letters. 4: 3005-7. PMID 12182610 DOI: 10.1021/Ol026433J  0.466
2002 Kozmin SA, Iwama T, Huang Y, Rawal VH. An efficient approach to Aspidosperma alkaloids via [4 + 2] cycloadditions of aminosiloxydienes: stereocontrolled total synthesis of (+/-)-tabersonine. Gram-scale catalytic asymmetric syntheses of (+)-tabersonine and (+)-16-methoxytabersonine. Asymmetric syntheses of (+)-aspidospermidine and (-)-quebrachamine. Journal of the American Chemical Society. 124: 4628-41. PMID 11971711 DOI: 10.1021/Ja017863S  0.712
2001 Schramm MP, Reddy DS, Kozmin SA. Siloxyalkyne-Alkene Metathesis: Rapid Access to Highly Functionalized Enones. Angewandte Chemie (International Ed. in English). 40: 4274-4277. PMID 29712103 DOI: 10.1002/1521-3773(20011119)40:22<4274::Aid-Anie4274>3.0.Co;2-#  0.727
2001 Smith AB, Adams CM, Kozmin SA. On the reversible nature of the olefin cross metathesis reaction. Journal of the American Chemical Society. 123: 990-1. PMID 11456640 DOI: 10.1021/Ja003745D  0.578
2001 Smith AB, Adams CM, Kozmin SA, Paone DV. Total synthesis of (-)-cylindrocyclophanes A and F exploiting the reversible nature of the olefin cross metathesis reaction. Journal of the American Chemical Society. 123: 5925-37. PMID 11414825 DOI: 10.1021/Ja0106164  0.57
2001 Kozmin SA. Efficient stereochemical relay en route to leucascandrolide A. Organic Letters. 3: 755-8. PMID 11259054 DOI: 10.1021/Ol015514X  0.33
2001 Schramm MP, Srinivasa Reddy D, Kozmin SA. Siloxyalkyne - Alkene metathesis: Rapid access to highly functionalized enones Angewandte Chemie - International Edition. 40: 4274-4277. DOI: 10.1002/1521-3773(20011119)40:22<4274::AID-ANIE4274>3.0.CO;2-#  0.623
2001 Kozmin SA, He S, Rawal VH. Preparation of (E)-1-dimethylamino-3-tert-butyldimethylsiloxy-1,3-butadiene Organic Syntheses. 78: 152-158.  0.49
2001 Kozmin SA, He S, Rawal VH. [4+2] Cycloaddition of 1-dimethylamino-3-tert-butyldimethylsiloxy-1,3- butadiene with methyl acrylate: 4-hydroxymethyl-2-cyclohexen-1-one Organic Syntheses. 78: 160-168.  0.515
2000 Janey JM, Iwama T, Kozmin SA, Rawal VH. Racemic and asymmetric Diels-Alder reactions of 1-(2-oxazolidinon-3-yl)-3-siloxy-1,3-butadienes. The Journal of Organic Chemistry. 65: 9059-68. PMID 11149852 DOI: 10.1021/Jo005619Y  0.657
2000 He S, Kozmin SA, Rawal VH. Highly diastereoselective asymmetric thio-Claisen rearrangements Journal of the American Chemical Society. 122: 190-191. DOI: 10.1021/Ja992959W  0.672
2000 Smith AB, Kozmin SA, Adams CM, Paone DV. Assembly of (-)-cylindrocyclophanes A and F via remarkable olefin metathesis dimerizations [3] Journal of the American Chemical Society. 122: 4984-4985. DOI: 10.1021/Ja000430P  0.495
1999 Kozmin SA, Janey JM, Rawal VH. 1-Amino-3-siloxy-1,3-butadienes: Highly Reactive Dienes for the Diels-Alder Reaction. The Journal of Organic Chemistry. 64: 3039-3052. PMID 11674400 DOI: 10.1021/Jo981563K  0.674
1999 Iwama T, Birman VB, Kozmin SA, Rawal VH. Regiocontrolled synthesis of carbocycle-fused indoles via arylation of silyl enol ethers with o-nitrophenylphenyliodonium fluoride. Organic Letters. 1: 673-6. PMID 10823199 DOI: 10.1021/Ol990759J  0.763
1999 Kozmin SA, Green MT, Rawal VH. On the reactivity of 1-amino-3-siloxy-1,3-dienes: Kinetics investigation and theoretical interpretation Journal of Organic Chemistry. 64: 8045-8047. DOI: 10.1021/Jo990923G  0.563
1999 Kozmin SA, Janey JM, Rawal VH. 1-amino-3-siloxy-1,3-butadienes: Highly reactive dienes for the Diels- Alder reaction Journal of Organic Chemistry. 64: 3039-3052. DOI: 10.1021/jo981563k  0.601
1999 Kozmin SA, Rawal VH. Chiral amino siloxy dienes in the Diels-Alder reaction: Applications to the asymmetric synthesis of 4-substituted and 4,5-disubstituted cyclohexenones and the total synthesis of (-)-α-elemene Journal of the American Chemical Society. 121: 9562-9573. DOI: 10.1021/Ja9921930  0.687
1998 Kozmin SA, Rawal VH. A general strategy to Aspidosperma alkaloids: Efficient, stereocontrolled synthesis of tabersonine [6] Journal of the American Chemical Society. 120: 13523-13524. DOI: 10.1021/Ja983198K  0.62
1998 Kozmin SA, Rawal VH. Asymmetric Diels-Alder reaction of chiral I-amino-3-siloxy-I,3-butadiene: Application to the enantioselective synthesis of (-)-α-elemene Chemtracts. 11: 41-45.  0.619
1997 Kozmin SA, Rawal VH. Preparation and Diels-Alder Reactivity of 1-Amino-3-siloxy-1,3-butadienes Journal of Organic Chemistry. 62: 5252-5253. DOI: 10.1021/Jo970438Q  0.602
1997 Kozmin SA, Rawal VH. Asymmetric Diels-Alder reactions of chiral 1-amino-3-siloxy-1,3- butadiene: Application to the enantioselective synthesis of (-)-α-elemene [5] Journal of the American Chemical Society. 119: 7165-7166. DOI: 10.1021/Ja971272D  0.654
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