Year |
Citation |
Score |
2023 |
Pan Y, Chen H, Zhang X, Liu W, Ding Y, Huang D, Zhai J, Wei W, Wen J, Chen D, Zhou Y, Liang C, Wong N, Man K, Cheung AH, et al. METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy. Cell Reports. Medicine. 4: 101144. PMID 37586322 DOI: 10.1016/j.xcrm.2023.101144 |
0.372 |
|
2023 |
Song Q, Zhang X, Liu W, Wei H, Liang W, Zhou Y, Ding Y, Ji F, Ho-Kwan Cheung A, Wong N, Yu J. Bifidobacterium pseudolongum-generated acetate suppresses non-alcoholic fatty liver disease-associated hepatocellular carcinoma. Journal of Hepatology. PMID 37459922 DOI: 10.1016/j.jhep.2023.07.005 |
0.334 |
|
2023 |
Yang Z, Gao S, Wong CC, Liu W, Chen H, Shang H, Wu ZY, Xu L, Zhang X, Wong N, Kuang M, Yu J. TUBB4B is a novel therapeutic target in nonalcoholic fatty liver disease-associated hepatocellular carcinoma. The Journal of Pathology. PMID 36787097 DOI: 10.1002/path.6065 |
0.422 |
|
2022 |
Lam YK, Yu J, Huang H, Ding X, Wong AM, Leung HH, Chan AW, Ng KK, Xu M, Wang X, Wong N. TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk. Hepatology (Baltimore, Md.). PMID 36221953 DOI: 10.1002/hep.32802 |
0.404 |
|
2022 |
Xu M, Liu Y, Wan HL, Wong AM, Ding X, You W, Lo WS, Ng KK, Wong N. Overexpression of nucleotide metabolic enzyme DUT in hepatocellular carcinoma potentiates a therapeutic opportunity through targeting its dUTPase activity. Cancer Letters. 548: 215898. PMID 36075487 DOI: 10.1016/j.canlet.2022.215898 |
0.444 |
|
2022 |
Chan SL, Wong N, Lam WKJ, Kuang M. Personalized treatment for hepatocellular carcinoma: Current status and Future perspectives. Journal of Gastroenterology and Hepatology. PMID 35570200 DOI: 10.1111/jgh.15889 |
0.34 |
|
2022 |
Wong AM, Ding X, Wong AM, Xu M, Zhang L, Leung HH, Chan AW, Song QX, Kwong J, Chan LK, Man M, He M, Chen J, Zhang Z, You W, ... ... Wong N, et al. Unique molecular characteristics of NAFLD-associated liver cancer accentuate β-catenin/TNFRSF19-mediated immune evasion. Journal of Hepatology. PMID 35351523 DOI: 10.1016/j.jhep.2022.03.015 |
0.34 |
|
2020 |
Zhang J, Wong CC, Leung KT, Wu F, Zhou Y, Tong JHM, Chan RCK, Li H, Wang Y, Yan H, Liu L, Wu WKK, Chan MWY, Cheng ASL, Yu J, ... Wong N, et al. FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential. Oncogene. PMID 32934314 DOI: 10.1038/S41388-020-01458-X |
0.33 |
|
2020 |
Ding X, He M, Chan AWH, Song QX, Sze SC, Chen H, Man MKH, Man K, Chan SL, Lai PBS, Wang X, Wong N. Genomic and Epigenomic Features of Primary and Recurrent Hepatocellular Carcinomas. Gastroenterology. PMID 32428506 DOI: 10.1053/J.Gastro.2019.09.056 |
0.475 |
|
2020 |
Zhou Y, Zhang J, Li H, Huang T, Wong CC, Wu F, Wu M, Weng N, Liu L, Cheng ASL, Yu J, Wong N, Lo KW, Tang PMK, Kang W, et al. AMOTL1 enhances YAP1 stability and promotes YAP1-driven gastric oncogenesis. Oncogene. PMID 32313226 DOI: 10.1038/S41388-020-1293-5 |
0.31 |
|
2020 |
Wong AMG, Cheung W, Wong M, Wong A, Lam H, Zhang Z, Man M, Chen H, Close D, Johnston P, Chan A, Lai P, Kwong J, Wong N. Abstract 3911: High-throughput screening of patient-derived HCC organoids for drug discovery Clinical Trials. DOI: 10.1158/1538-7445.Am2020-3911 |
0.38 |
|
2019 |
Ding X, He M, Chan AWH, Song QX, Sze SC, Chen H, Man MKH, Man K, Chan SL, Lai PBS, Wang X, Wong N. Genomic and Epigenomic Features of Primary and Recurrent Hepatocellular Carcinomas. Gastroenterology. PMID 31560893 DOI: 10.1053/j.gastro.2019.09.005 |
0.379 |
|
2019 |
Wong N. Frequent Integration of HBV DNA in Genomes of Hepatocellular Carcinoma Cells from Patients with Occult Infections. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 31473360 DOI: 10.1016/J.Cgh.2019.08.045 |
0.413 |
|
2019 |
Chen H, Wong CC, Liu D, Go MYY, Wu B, Peng S, Kuang M, Wong N, Yu J. APLN promotes hepatocellular carcinoma through activating PI3K/Akt pathway and is a druggable target. Theranostics. 9: 5246-5260. PMID 31410213 DOI: 10.7150/Thno.34713 |
0.521 |
|
2019 |
Chan AW, Zhang Z, Chong CC, Tin EK, Chow C, Wong N. Genomic landscape of lymphoepithelioma-like hepatocellular carcinoma. The Journal of Pathology. PMID 31168847 DOI: 10.1002/Path.5313 |
0.525 |
|
2019 |
Chen X, Kost J, Sulovari A, Wong N, Liang W, Cao J, Li D. A virome-wide clonal integration analysis platform for discovering cancer viral etiology. Genome Research. PMID 30872350 DOI: 10.1101/Gr.242529.118 |
0.312 |
|
2019 |
Xiong L, Wu F, Wu Q, Xu L, Cheung OK, Kang W, Mok MT, Szeto LLM, Lun CY, Lung RW, Zhang J, Yu KH, Lee SD, Huang G, Wang CM, ... ... Wong N, et al. Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming. Nature Communications. 10: 335. PMID 30659195 DOI: 10.1038/S41467-018-08245-Z |
0.476 |
|
2019 |
Chen H, Gao F, He M, Ding XF, Wong AM, Sze SC, Yu AC, Sun T, Chan AW, Wang X, Wong N. Long-read RNA Sequencing identifies Novel Splice Variants in Hepatocellular Carcinoma and Tumor-specific Isoforms. Hepatology (Baltimore, Md.). PMID 30637779 DOI: 10.1002/Hep.30500 |
0.525 |
|
2018 |
Liu D, Wong CC, Fu L, Chen H, Zhao L, Li C, Zhou Y, Zhang Y, Xu W, Yang Y, Wu B, Cheng G, Lai PB, Wong N, Sung JJY, et al. Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target. Science Translational Medicine. 10. PMID 29669855 DOI: 10.1126/Scitranslmed.Aap9840 |
0.526 |
|
2017 |
Huang T, Zhou Y, Zhang J, Wong CC, Li W, Kwan JSH, Yang R, Chan AKY, Dong Y, Wu F, Zhang B, Cheung AHK, Wu WKK, Cheng ASL, Yu J, ... Wong N, et al. SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis. Oncogene. PMID 29234151 DOI: 10.1038/S41388-017-0029-7 |
0.33 |
|
2017 |
Xu W, Zhang X, Wu JL, Fu L, Liu K, Liu D, Chen GG, Lai PB, Wong N, Yu J. O-GlcNAc transferase promotes fatty liver-associated liver cancer through inducing palmitic acid and activating endoplasmic reticulum stress. Journal of Hepatology. PMID 28347804 DOI: 10.1016/J.Jhep.2017.03.017 |
0.382 |
|
2017 |
Chai S, Ng K, Tong M, Lau EY, Lee TK, Chan KW, Yuan YF, Cheung TT, Cheung ST, Wang XQ, Wong N, Lo CM, Man K, Guan XY, Ma SK. Abstract 2895: Octamer-4/microRNA-1246 signaling axis drives Wnt/β-catenin activation in liver cancer stem cells Cancer Research. 77: 2895-2895. DOI: 10.1158/1538-7445.Am2017-2895 |
0.45 |
|
2016 |
Chai S, Ng KY, Tong M, Lau EY, Lee TK, Wah Chan K, Yuan YF, Cheung TT, Cheung ST, Wang XQ, Wong N, Lo CM, Man K, Guan XY, Ma S. Oct4/miR-1246 signaling axis drives Wnt/β-catenin activation in liver cancer stem cells. Hepatology (Baltimore, Md.). PMID 27639189 DOI: 10.1002/hep.28821 |
0.315 |
|
2016 |
Tang S, Wu WK, Li X, Wong SH, Wong N, Chan MT, Sung JJ, Yu J. Stratification of Digestive Cancers with Different Pathological Features and Survival Outcomes by MicroRNA Expression. Scientific Reports. 6: 24466. PMID 27080237 DOI: 10.1038/Srep24466 |
0.349 |
|
2016 |
Chan SL, Wong AM, Lee K, Wong N, Chan AK. Personalized therapy for hepatocellular carcinoma: Where are we now? Cancer Treatment Reviews. 45: 77-86. PMID 26995632 DOI: 10.1016/J.Ctrv.2016.02.008 |
0.448 |
|
2016 |
Ng KT, Lo CM, Wong N, Li CX, Qi X, Liu XB, Geng W, Yeung OW, Ma YY, Chan SC, Man K. Early-phase circulating miRNAs predict tumor recurrence and survival of hepatocellular carcinoma patients after liver transplantation. Oncotarget. PMID 26918346 DOI: 10.18632/Oncotarget.7627 |
0.44 |
|
2016 |
Tsang DP, Wu WK, Kang W, Lee YY, Wu F, Yu Z, Xiong L, Chan AW, Tong JH, Yang W, Li MS, Lau SS, Li X, Lee SD, Yang Y, ... ... Wong N, et al. Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates Nuclear Factor-κB in hepatocellular carcinoma. The Journal of Pathology. PMID 26800240 DOI: 10.1002/Path.4688 |
0.516 |
|
2016 |
Wu F, Lee Y, Lee SD, Tan P, Wong N, Yip KY, To KF, Cheng ASL. Abstract 4519: Nanoscale ChIP-seq analysis in primary hepatocellular carcinoma tissues reveals tumor-specific chromatin deregulation for oncogene activation Cancer Research. 76: 4519-4519. DOI: 10.1158/1538-7445.Am2016-4519 |
0.491 |
|
2015 |
Song Y, Pan G, Chen L, Ma S, Zeng T, Chan TH, Li L, Lian Q, Chow R, Cai X, Li Y, Li Y, Liu M, Li Y, Zhu Y, ... Wong N, et al. Loss of ATOH8 Increases Stem Cell Features of Hepatocellular Carcinoma Cells. Gastroenterology. PMID 26099525 DOI: 10.1053/J.Gastro.2015.06.010 |
0.504 |
|
2015 |
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N. Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs. Carcinogenesis. PMID 26054723 DOI: 10.1093/Carcin/Bgv081 |
0.514 |
|
2015 |
Leung WK, He M, Chan AW, Law PT, Wong N. Wnt/β-Catenin activates MiR-183/96/182 expression in hepatocellular carcinoma that promotes cell invasion. Cancer Letters. 362: 97-105. PMID 25813403 DOI: 10.1016/J.Canlet.2015.03.023 |
0.448 |
|
2015 |
Wong N, He M. Abstract LB-030: Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-030 |
0.401 |
|
2014 |
Cheung PF, Yip CW, Ng LW, Lo KW, Wong N, Choy KW, Chow C, Chan KF, Cheung TT, Poon RT, Fan ST, Cheung ST. Establishment and characterization of a novel primary hepatocellular carcinoma cell line with metastatic ability in vivo. Cancer Cell International. 14: 103. PMID 25349534 DOI: 10.1186/S12935-014-0103-Y |
0.501 |
|
2014 |
Chai S, Tong M, Ng KY, Kwan PS, Chan YP, Fung TM, Lee TK, Wong N, Xie D, Yuan YF, Guan XY, Ma S. Regulatory role of miR-142-3p on the functional hepatic cancer stem cell marker CD133. Oncotarget. 5: 5725-35. PMID 25015418 DOI: 10.18632/Oncotarget.2167 |
0.436 |
|
2014 |
Sun T, Co NN, Wong N. PFTK1 interacts with cyclin Y to activate non-canonical Wnt signaling in hepatocellular carcinoma. Biochemical and Biophysical Research Communications. 449: 163-8. PMID 24824184 DOI: 10.1016/J.Bbrc.2014.05.002 |
0.477 |
|
2014 |
Lai KP, Chen J, He M, Ching AK, Lau C, Lai PB, To KF, Wong N. Overexpression of ZFX confers self-renewal and chemoresistance properties in hepatocellular carcinoma. International Journal of Cancer. Journal International Du Cancer. 135: 1790-9. PMID 24585547 DOI: 10.1002/Ijc.28819 |
0.521 |
|
2014 |
Lau CC, Sun T, Ching AK, He M, Li JW, Wong AM, Co NN, Chan AW, Li PS, Lung RW, Tong JH, Lai PB, Chan HL, To KF, Chan TF, ... Wong N, et al. Viral-human chimeric transcript predisposes risk to liver cancer development and progression. Cancer Cell. 25: 335-49. PMID 24582836 DOI: 10.1016/J.Ccr.2014.01.030 |
0.749 |
|
2014 |
Qi YJ, Ward DG, Pang C, Wang QM, Wei W, Ma J, Zhang J, Lou Q, Shimwell NJ, Martin A, Wong N, Chao WX, Wang M, Ma YF, Johnson PJ. Proteomic profiling of N-linked glycoproteins identifies ConA-binding procathepsin D as a novel serum biomarker for hepatocellular carcinoma. Proteomics. 14: 186-95. PMID 24259486 DOI: 10.1002/Pmic.201300226 |
0.484 |
|
2014 |
Ling CC, Ng KT, Shao Y, Geng W, Xiao JW, Liu H, Li CX, Liu XB, Ma YY, Yeung WH, Qi X, Yu J, Wong N, Zhai Y, Chan SC, et al. Post-transplant endothelial progenitor cell mobilization via CXCL10/CXCR3 signaling promotes liver tumor growth. Journal of Hepatology. 60: 103-9. PMID 23994383 DOI: 10.1016/J.Jhep.2013.08.017 |
0.365 |
|
2014 |
Ng KY, Chai S, Tong M, Kwan PS, Chan YP, Lee TKW, Wong N, Guan X, Ma S. Abstract LB-53: Regulatory role of miR-142-3p on the functional hepatic cancer stem cell marker CD133 Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-53 |
0.428 |
|
2013 |
Chung GT, Lung RW, Hui AB, Yip KY, Woo JK, Chow C, Tong CY, Lee SD, Yuen JW, Lun SW, Tso KK, Wong N, Tsao SW, Yip TT, Busson P, et al. Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma. The Journal of Pathology. 231: 158-67. PMID 23878065 DOI: 10.1002/Path.4240 |
0.389 |
|
2013 |
Yu J, Shen J, Sun TT, Zhang X, Wong N. Obesity, insulin resistance, NASH and hepatocellular carcinoma. Seminars in Cancer Biology. 23: 483-91. PMID 23876851 DOI: 10.1016/J.Semcancer.2013.07.003 |
0.384 |
|
2013 |
Law PT, Qin H, Ching AK, Lai KP, Co NN, He M, Lung RW, Chan AW, Chan TF, Wong N. Deep sequencing of small RNA transcriptome reveals novel non-coding RNAs in hepatocellular carcinoma. Journal of Hepatology. 58: 1165-73. PMID 23376363 DOI: 10.1016/J.Jhep.2013.01.032 |
0.409 |
|
2012 |
Cheng IK, Tsang BC, Lai KP, Ching AK, Chan AW, To KF, Lai PB, Wong N. GEF-H1 over-expression in hepatocellular carcinoma promotes cell motility via activation of RhoA signalling. The Journal of Pathology. 228: 575-85. PMID 22847784 DOI: 10.1002/Path.4084 |
0.483 |
|
2012 |
Kang W, Tong JH, Chan AW, Lung RW, Chau SL, Wong QW, Wong N, Yu J, Cheng AS, To KF. Stathmin1 plays oncogenic role and is a target of microRNA-223 in gastric cancer. Plos One. 7: e33919. PMID 22470493 DOI: 10.1371/Journal.Pone.0033919 |
0.325 |
|
2012 |
Law PT, Ching AK, Chan AW, Wong QW, Wong CK, To KF, Wong N. MiR-145 modulates multiple components of the insulin-like growth factor pathway in hepatocellular carcinoma. Carcinogenesis. 33: 1134-41. PMID 22431718 DOI: 10.1093/Carcin/Bgs130 |
0.375 |
|
2012 |
Chow C, Wong N, Pagano M, Lun SW, Nakayama KI, Nakayama K, Lo KW. Regulation of APC/CCdc20 activity by RASSF1A-APC/CCdc20 circuitry. Oncogene. 31: 1975-87. PMID 21874044 DOI: 10.1038/Onc.2011.372 |
0.319 |
|
2012 |
Leung W, He M, Law P, Ching A, Chan A, Wong N. Abstract 4127: MiR-183/96/182 cluster confers cell motile advantages in hepatocellular carcinoma Cancer Research. 72: 4127-4127. DOI: 10.1158/1538-7445.Am2012-4127 |
0.368 |
|
2011 |
Yip WK, Cheng AS, Zhu R, Lung RW, Tsang DP, Lau SS, Chen Y, Sung JG, Lai PB, Ng EK, Yu J, Wong N, To KF, Wong VW, Sung JJ, et al. Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in hepatocellular carcinoma development. Plos One. 6: e22888. PMID 21829663 DOI: 10.1371/Journal.Pone.0022888 |
0.386 |
|
2011 |
Leung WK, Ching AK, Chan AW, Poon TC, Mian H, Wong AS, To KF, Wong N. A novel interplay between oncogenic PFTK1 protein kinase and tumor suppressor TAGLN2 in the control of liver cancer cell motility. Oncogene. 30: 4464-75. PMID 21577206 DOI: 10.1038/Onc.2011.161 |
0.462 |
|
2011 |
Sun CK, Ng KT, Lim ZX, Cheng Q, Lo CM, Poon RT, Man K, Wong N, Fan ST. Proline-rich tyrosine kinase 2 (Pyk2) promotes cell motility of hepatocellular carcinoma through induction of epithelial to mesenchymal transition. Plos One. 6: e18878. PMID 21533080 DOI: 10.1371/Journal.Pone.0018878 |
0.466 |
|
2011 |
Chen J, Zhang B, Wong N, Lo AW, To KF, Chan AW, Ng MH, Ho CY, Cheng SH, Lai PB, Yu J, Ng HK, Ling MT, Huang AL, Cai XF, et al. Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth. Cancer Research. 71: 4138-49. PMID 21527554 DOI: 10.1158/0008-5472.Can-10-4274 |
0.543 |
|
2011 |
Chung KY, Cheng IK, Ching AK, Chu JH, Lai PB, Wong N. Block of proliferation 1 (BOP1) plays an oncogenic role in hepatocellular carcinoma by promoting epithelial-to-mesenchymal transition. Hepatology (Baltimore, Md.). 54: 307-18. PMID 21520196 DOI: 10.1002/Hep.24372 |
0.562 |
|
2011 |
Cheng AS, Lau SS, Chen Y, Kondo Y, Li MS, Feng H, Ching AK, Cheung KF, Wong HK, Tong JH, Jin H, Choy KW, Yu J, To KF, Wong N, et al. EZH2-mediated concordant repression of Wnt antagonists promotes β-catenin-dependent hepatocarcinogenesis. Cancer Research. 71: 4028-39. PMID 21512140 DOI: 10.1158/0008-5472.Can-10-3342 |
0.481 |
|
2011 |
Law PT, Wong N. Emerging roles of microRNA in the intracellular signaling networks of hepatocellular carcinoma. Journal of Gastroenterology and Hepatology. 26: 437-49. PMID 21332540 DOI: 10.1111/J.1440-1746.2010.06512.X |
0.39 |
|
2011 |
Zhou Q, Ching AK, Leung WK, Szeto CY, Ho SM, Chan PK, Yuan YF, Lai PB, Yeo W, Wong N. Novel therapeutic potential in targeting microtubules by nanoparticle albumin-bound paclitaxel in hepatocellular carcinoma. International Journal of Oncology. 38: 721-31. PMID 21240457 DOI: 10.3892/Ijo.2011.902 |
0.485 |
|
2011 |
Leung WK, Ching AK, Wong N. Phosphorylation of Caldesmon by PFTAIRE1 kinase promotes actin binding and formation of stress fibers. Molecular and Cellular Biochemistry. 350: 201-6. PMID 21184254 DOI: 10.1007/S11010-010-0699-8 |
0.335 |
|
2011 |
Tsang DP, Lau SS, Lee TL, Wong N, Cheng AS. Abstract 1185: EZH2-mediated H3K27 trimethylation silencing of microRNAs in hepatocellular carcinoma Cancer Research. 71: 1185-1185. DOI: 10.1158/1538-7445.Am2011-1185 |
0.428 |
|
2010 |
Ma S, Tang KH, Chan YP, Lee TK, Kwan PS, Castilho A, Ng I, Man K, Wong N, To KF, Zheng BJ, Lai PB, Lo CM, Chan KW, Guan XY. miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1. Cell Stem Cell. 7: 694-707. PMID 21112564 DOI: 10.1016/J.Stem.2010.11.010 |
0.402 |
|
2010 |
Wong QW, Ching AK, Chan AW, Choy KW, To KF, Lai PB, Wong N. MiR-222 overexpression confers cell migratory advantages in hepatocellular carcinoma through enhancing AKT signaling. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 867-75. PMID 20103675 DOI: 10.1158/1078-0432.Ccr-09-1840 |
0.447 |
|
2010 |
Cheng IK, Ching AK, Chan TC, Chan AW, Wong CK, Choy KW, Kwan M, Lai PB, Wong N. Reduced CRYL1 expression in hepatocellular carcinoma confers cell growth advantages and correlates with adverse patient prognosis. The Journal of Pathology. 220: 348-60. PMID 19927314 DOI: 10.1002/Path.2644 |
0.554 |
|
2010 |
Leung WK, Ching AK, Chan AW, Poon TC, To K, Wong AS, Wong N. Abstract 5297: A novel role of cdc-family genePFTK1in the control of liver cancer cell motility Cancer Research. 70: 5297-5297. DOI: 10.1158/1538-7445.Am10-5297 |
0.531 |
|
2010 |
Cheng AS, Lau S, Chen Y, Kondo Y, Li M, Feng H, Ching A, Cheung P, Wong K, Jin H, Choy R, Yu J, To KF, Wong N, Huang T, et al. Abstract 4881: Polycomb protein EZH2 activates Wnt/β-catenin signaling to promote hepatocellular carcinoma development Cancer Research. 70: 4881-4881. DOI: 10.1158/1538-7445.Am10-4881 |
0.428 |
|
2010 |
Zhou Q, Ching AK, Leung WK, Szeto C, Ho S, Holmes CC, Yuan Y, Lai PB, Yeo W, Wong N. Abstract 4423: Novel therapeutic potential in targeting the microtubules by nanoparticle albumin-bound paclitaxel in hepatocellular carcinoma Cancer Research. 70: 4423-4423. DOI: 10.1158/1538-7445.Am10-4423 |
0.471 |
|
2010 |
Law PT, Ching AK, Wong QW, Lai PB, Wong N. Abstract 2091: MiR-145 functions as a potential tumor suppressor in hepatocellular carcinoma Cancer Research. 70: 2091-2091. DOI: 10.1158/1538-7445.Am10-2091 |
0.435 |
|
2010 |
Man K, Shao Y, Ng K, Wong N, Liu X, Li C, Fan S, Lo C. The significance of acute-phase small-for-size liver graft injury in mobilization of circulating EPCs/MDSCs/Tregs after LDLT for HCC patients Transplantation. 90: 268. DOI: 10.1097/00007890-201007272-00505 |
0.363 |
|
2009 |
Yin LL, Chung CM, Chen J, Fok KL, Ng CP, Jia RR, Ren X, Zhou J, Zhang T, Zhao XH, Lin M, Zhu H, Zhang XH, Tsang LL, Bi Y, ... ... Wong N, et al. A suppressor of multiple extracellular matrix-degrading proteases and cancer metastasis. Journal of Cellular and Molecular Medicine. 13: 4034-41. PMID 19017363 DOI: 10.1111/J.1582-4934.2008.00576.X |
0.304 |
|
2009 |
Wong N, Yeo W, Wong WL, Wong NL, Chan KY, Mo FK, Koh J, Chan SL, Chan AT, Lai PB, Ching AK, Tong JH, Ng HK, Johnson PJ, To KF. TOP2A overexpression in hepatocellular carcinoma correlates with early age onset, shorter patients survival and chemoresistance. International Journal of Cancer. Journal International Du Cancer. 124: 644-52. PMID 19003983 DOI: 10.1002/Ijc.23968 |
0.525 |
|
2008 |
Gho JW, Ip WK, Chan KY, Law PT, Lai PB, Wong N. Re-expression of transcription factor ATF5 in hepatocellular carcinoma induces G2-M arrest. Cancer Research. 68: 6743-51. PMID 18701499 DOI: 10.1158/0008-5472.Can-07-6469 |
0.552 |
|
2008 |
Wong QW, Lung RW, Law PT, Lai PB, Chan KY, To KF, Wong N. MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1. Gastroenterology. 135: 257-69. PMID 18555017 DOI: 10.1053/J.Gastro.2008.04.003 |
0.387 |
|
2008 |
Cheung YS, Chan HL, Wong J, Lee KF, Poon TC, Wong N, Lai PB. Elevated perioperative transaminase level predicts intrahepatic recurrence in hepatitis B-related hepatocellular carcinoma after curative hepatectomy. Asian Journal of Surgery / Asian Surgical Association. 31: 41-9. PMID 18490213 DOI: 10.1016/S1015-9584(08)60056-1 |
0.412 |
|
2008 |
Lung HL, Lo CC, Wong CC, Cheung AK, Cheong KF, Wong N, Kwong FM, Chan KC, Law EW, Tsao SW, Chua D, Sham JS, Cheng Y, Stanbridge EJ, Robertson GP, et al. Identification of tumor suppressive activity by irradiation microcell-mediated chromosome transfer and involvement of alpha B-crystallin in nasopharyngeal carcinoma. International Journal of Cancer. Journal International Du Cancer. 122: 1288-96. PMID 18027848 DOI: 10.1002/Ijc.23259 |
0.371 |
|
2007 |
Pang EY, Bai AH, To KF, Sy SM, Wong NL, Lai PB, Squire JA, Wong N. Identification of PFTAIRE protein kinase 1, a novel cell division cycle-2 related gene, in the motile phenotype of hepatocellular carcinoma cells. Hepatology (Baltimore, Md.). 46: 436-45. PMID 17559150 DOI: 10.1002/Hep.21691 |
0.55 |
|
2007 |
Cheng AS, Wong N, Tse AM, Chan KY, Chan KK, Sung JJ, Chan HL. RNA interference targeting HBx suppresses tumor growth and enhances cisplatin chemosensitivity in human hepatocellular carcinoma. Cancer Letters. 253: 43-52. PMID 17296261 DOI: 10.1016/J.Canlet.2007.01.004 |
0.51 |
|
2007 |
Ip WK, Lai PB, Wong NL, Sy SM, Beheshti B, Squire JA, Wong N. Identification of PEG10 as a progression related biomarker for hepatocellular carcinoma. Cancer Letters. 250: 284-91. PMID 17126992 DOI: 10.1016/J.Canlet.2006.10.012 |
0.535 |
|
2007 |
Bowles E, Corson TW, Bayani J, Squire JA, Wong N, Lai PB, Gallie BL. Profiling genomic copy number changes in retinoblastoma beyond loss of RB1. Genes, Chromosomes & Cancer. 46: 118-29. PMID 17099872 DOI: 10.1002/Gcc.20383 |
0.407 |
|
2006 |
Lam TW, Tong JH, To KF, Chan A, Liew CT, Lai PB, Wong N. Correlative Analysis of DNA Methyltransferase Expression and Promoter Hypermethylation of Tumor Suppressor Genes in Hepatocellular Carcinoma. Cancer Genomics & Proteomics. 3: 271-277. PMID 31394707 |
0.318 |
|
2006 |
Zee BC, Lee J, Wong N, Yeo W, Lai P, Chan L, Hui P, Wong H, Lam K, Ho W, Chan AT. Wavelet-based prognostic model with comparative genomic hybridization (CGH) data in patients with hepatocellular carcinoma (HCC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 20026. PMID 27952766 DOI: 10.1200/Jco.2006.24.18_Suppl.20026 |
0.433 |
|
2006 |
Poon TC, Wong N, Lai PB, Rattray M, Johnson PJ, Sung JJ. A tumor progression model for hepatocellular carcinoma: bioinformatic analysis of genomic data. Gastroenterology. 131: 1262-70. PMID 17030195 DOI: 10.1053/J.Gastro.2006.08.014 |
0.497 |
|
2006 |
Chan KYY, Lai PBS, Squire JA, Beheshti B, Wong NLY, Sy SMH, Wong N. Positional expression profiling indicates candidate genes in deletion hotspots of hepatocellular carcinoma Modern Pathology. 19: 1546-1554. PMID 16980951 DOI: 10.1038/Modpathol.3800674 |
0.496 |
|
2006 |
Hau PM, Siu WY, Wong N, Lai PB, Poon RY. Polyploidization increases the sensitivity to DNA-damaging agents in mammalian cells. Febs Letters. 580: 4727-36. PMID 16887121 DOI: 10.1016/J.Febslet.2006.07.059 |
0.308 |
|
2006 |
Sy SM, Lai PB, Pang E, Wong NL, To KF, Johnson PJ, Wong N. Novel identification of zyxin upregulations in the motile phenotype of hepatocellular carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 19: 1108-16. PMID 16680155 DOI: 10.1038/Modpathol.3800626 |
0.49 |
|
2005 |
Wong QW, Wong N, Lai PB, To KF, Wong N. Clonal relationship of tumor nodules in hepatocellular carcinoma: a hierarchical clustering analysis of comparative genomic hybridization data. Human Pathology. 36: 893-8. PMID 16112006 DOI: 10.1016/J.Humpath.2005.06.007 |
0.475 |
|
2005 |
Yeo W, Wong N, Wong WL, Lai PB, Zhong S, Johnson PJ. High frequency of promoter hypermethylation of RASSF1A in tumor and plasma of patients with hepatocellular carcinoma. Liver International : Official Journal of the International Association For the Study of the Liver. 25: 266-72. PMID 15780049 DOI: 10.1111/J.1478-3231.2005.01084.X |
0.441 |
|
2005 |
Pang E, Hu Y, Chan KYY, Lai PBS, Squire JA, Macgregor PF, Beheshti B, Albert M, Leung TWT, Wong N. Karyotypic imbalances and differential gene expressions in the acquired doxorubicin resistance of hepatocellular carcinoma cells Laboratory Investigation. 85: 664-674. PMID 15765123 DOI: 10.1038/Labinvest.3700254 |
0.434 |
|
2005 |
Chan KYY, Wong N, Lai PBS, Squire JA, Macgregor PF, Beheshti B, Albert M, To KF, Johnson PJ. Transcriptional profiling on chromosome 19p indicated frequent downregulation of ACP5 expression in hepatocellular carcinoma International Journal of Cancer. 114: 902-908. PMID 15645427 DOI: 10.1002/Ijc.20684 |
0.54 |
|
2005 |
Sy SM, Wong N, Lai PB, To KF, Johnson PJ. Regional over-representations on chromosomes 1q, 3q and 7q in the progression of hepatitis B virus-related hepatocellular carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 18: 686-92. PMID 15605078 DOI: 10.1038/Modpathol.3800345 |
0.441 |
|
2004 |
Hu Y, Pang E, Lai PBS, Squire JA, MacGregor PF, Beheshti B, Albert M, Leung TWT, Wong N. Genetic alterations in doxorubicin-resistant hepatocellular carcinoma cells: a combined study of spectral karyotyping, positional expression profiling and candidate genes International Journal of Oncology. 25: 1357-1364. PMID 15492826 DOI: 10.3892/Ijo.25.5.1357 |
0.454 |
|
2004 |
Sy SM, Fan B, Lee TW, Mok TS, Pang E, Yim A, Wong N. Spectral karyotyping indicates complex rearrangements in lung adenocarcinoma of nonsmokers. Cancer Genetics and Cytogenetics. 153: 57-9. PMID 15325095 DOI: 10.1016/J.Cancergencyto.2003.11.013 |
0.32 |
|
2004 |
Pang RTK, Poon TCW, Wong N, Lai PBS, Wong NLY, Chan CML, Yu JWS, Chan AT, Sung JJY. Comparison of protein expression patterns between hepatocellular carcinoma cell lines and a hepatoblastoma cell line Clinical Proteomics. 1: 313-331. DOI: 10.1385/Cp:1:3-4:313 |
0.455 |
|
2003 |
Zhong S, Yeo W, Tang MW, Wong N, Lai PB, Johnson PJ. Intensive hypermethylation of the CpG island of Ras association domain family 1A in hepatitis B virus-associated hepatocellular carcinomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 3376-82. PMID 12960125 |
0.325 |
|
2003 |
Cheng AS, Chan HL, Leung WK, Wong N, Johnson PJ, Sung JJ. Specific COX-2 inhibitor, NS-398, suppresses cellular proliferation and induces apoptosis in human hepatocellular carcinoma cells. International Journal of Oncology. 23: 113-9. PMID 12792783 DOI: 10.3892/Ijo.23.1.113 |
0.438 |
|
2003 |
Ng MH, Wong N, Lau TT, Tsang KS, Cheng SH, Chan NP, Tang SH, Lei KI, Leung Y. Chromosomal aberrations of multiple myeloma in Chinese patients at diagnosis: a study by combined G-banding and multicolor spectral karyotyping. Oncology Reports. 10: 587-91. PMID 12684628 DOI: 10.3892/Or.10.3.587 |
0.303 |
|
2003 |
Wong N, Hui AB, Fan B, Lo KW, Pang E, Leung SF, Huang DP, Johnson PJ. Molecular cytogenetic characterization of nasopharyngeal carcinoma cell lines and xenografts by comparative genomic hybridization and spectral karyotyping. Cancer Genetics and Cytogenetics. 140: 124-32. PMID 12645650 DOI: 10.1016/S0165-4608(02)00657-X |
0.376 |
|
2003 |
Wong N, Chan A, Lee SW, Lam E, To KF, Lai PB, Li XN, Liew CT, Johnson PJ. Positional mapping for amplified DNA sequences on 1q21-q22 in hepatocellular carcinoma indicates candidate genes over-expression. Journal of Hepatology. 38: 298-306. PMID 12586295 DOI: 10.1016/S0168-8278(02)00412-9 |
0.456 |
|
2002 |
Leung TH, Wong N, Lai PB, Chan A, To KF, Liew CT, Lau WY, Johnson PJ. Identification of four distinct regions of allelic imbalances on chromosome 1 by the combined comparative genomic hybridization and microsatellite analysis on hepatocellular carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 15: 1213-20. PMID 12429801 DOI: 10.1097/01.Mp.0000036347.66943.3C |
0.409 |
|
2002 |
Wong N, Li L, Tsang K, Lai PB, To KF, Johnson PJ. Frequent loss of chromosome 3p and hypermethylation of RASSF1A in cholangiocarcinoma. Journal of Hepatology. 37: 633-9. PMID 12399230 DOI: 10.1016/S0168-8278(02)00269-6 |
0.351 |
|
2002 |
Pang E, Wong N, Lai PB, To KF, Lau WY, Johnson PJ. Consistent chromosome 10 rearrangements in four newly established human hepatocellular carcinoma cell lines. Genes, Chromosomes & Cancer. 33: 150-9. PMID 11793441 DOI: 10.1002/Gcc.1220 |
0.425 |
|
2001 |
Ng MH, Wong N, Tsang KS, Cheng SH, Chung YF, Lo KW. Recurrent chromosomal rearrangements involving breakpoints 3p21 and 19q13 in Chinese IgD multiple myeloma detected by G-banding and multicolor spectral karyotyping: a review of IgD karyotype literature. Human Pathology. 32: 1016-20. PMID 11567234 DOI: 10.1053/Hupa.2001.27122 |
0.302 |
|
2001 |
Wong N, Lam WC, Lai PB, Pang E, Lau WY, Johnson PJ. Hypomethylation of chromosome 1 heterochromatin DNA correlates with q-arm copy gain in human hepatocellular carcinoma. The American Journal of Pathology. 159: 465-71. PMID 11485905 DOI: 10.1016/S0002-9440(10)61718-X |
0.475 |
|
2001 |
Fung LF, Wong N, Tang N, Lau A, Wong V, Pang CP, Suen M, King W, Johnson PJ. Genetic imbalances in pT2 breast cancers of southern Chinese women. Cancer Genetics and Cytogenetics. 124: 56-61. PMID 11165323 DOI: 10.1016/S0165-4608(00)00328-9 |
0.321 |
|
2001 |
Tang JCO, Wan TSK, Wong N, Pang E, Lam KY, Law SY, Chow LMC, Ma ESK, Chan LC, Wong J, Srivastava G. Establishment and characterization of a new xenograft-derived human esophageal squamous cell carcinoma cell line SLMT-1 of Chinese origin Cancer Genetics and Cytogenetics. 124: 36-41. PMID 11165320 DOI: 10.1016/S0165-4608(00)00317-4 |
0.42 |
|
2000 |
Lau WY, Lai PB, Leung MF, Leung BC, Wong N, Chen G, Leung TW, Liew CT. Differential gene expression of hepatocellular carcinoma using cDNA microarray analysis. Oncology Research. 12: 59-69. PMID 11132925 DOI: 10.3727/096504001108747530 |
0.45 |
|
2000 |
Wong N, Lai P, Pang E, Leung TW, Lau JW, Johnson PJ. A comprehensive karyotypic study on human hepatocellular carcinoma by spectral karyotyping. Hepatology. 32: 1060-1068. PMID 11050057 DOI: 10.1053/Jhep.2000.19349 |
0.403 |
|
2000 |
Pang E, Wong N, Lai PB-, To K, Lau JW-, Johnson PJ. A comprehensive karyotypic analysis on a newly developed hepatocellular carcinoma cell line, HKCI-1, by spectral karyotyping and comparative genomic hybridization Cancer Genetics and Cytogenetics. 121: 9-16. PMID 10958934 DOI: 10.1016/S0165-4608(99)00247-2 |
0.41 |
|
2000 |
Wong N, Wong KF, Chan JKC, Johnson PJ. Chromosomal translocations are common in natural killer-cell lymphoma/leukemia as shown by spectral karyotyping Human Pathology. 31: 771-774. PMID 10872675 DOI: 10.1053/Hupa.2000.7625 |
0.325 |
|
2000 |
Fan CS, Wong N, Leung S, To KF, Lo KW, Lee SW, Mok TS, Johnson PJ, Huang DP. Frequent c-myc and Int-2 overrepresentations in nasopharyngeal carcinoma. Human Pathology. 31: 169-178. PMID 10685630 DOI: 10.1016/S0046-8177(00)80216-6 |
0.341 |
|
1999 |
Cheung ST, Huang DP, Hui AB, Lo KW, Ko CW, Tsang YS, Wong N, Whitney BM, Lee JC. Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus. International Journal of Cancer. Journal International Du Cancer. 83: 121-6. PMID 10449618 DOI: 10.1002/(Sici)1097-0215(19990924)83:1<121::Aid-Ijc21>3.0.Co;2-F |
0.37 |
|
1999 |
Hui AB, Lo KW, Leung SF, Teo P, Fung MK, To KF, Wong N, Choi PH, Lee JC, Huang DP. Detection of recurrent chromosomal gains and losses in primary nasopharyngeal carcinoma by comparative genomic hybridisation. International Journal of Cancer. 82: 498-503. PMID 10404061 DOI: 10.1002/(Sici)1097-0215(19990812)82:4<498::Aid-Ijc5>3.0.Co;2-S |
0.359 |
|
1999 |
Su X, Wong N, Cao Q, Yu L, Niu C, Wickham N, Johnson PJ, Chen Z, Chen S. Chromosomal aberrations during progression of chronic myeloid leukemia identified by cytogenetic and molecular cytogenetic tools: implication of 1q12-21. Cancer Genetics and Cytogenetics. 108: 6-12. PMID 9973917 DOI: 10.1016/S0165-4608(98)00120-4 |
0.317 |
|
1999 |
Wong N, Lai P, Lee S, Fan S, Pang E, Liew C, Sheng Z, Lau JW, Johnson PJ. Assessment of Genetic Changes in Hepatocellular Carcinoma by Comparative Genomic Hybridization Analysis: Relationship to Disease Stage, Tumor Size, and Cirrhosis American Journal of Pathology. 154: 37-43. PMID 9916916 DOI: 10.1016/S0002-9440(10)65248-0 |
0.503 |
|
1998 |
Wong N, Chen S, Cao Q, Su X, Niu C, Wu Q, Leung TWT, Wickham N, Johnson PJ, Chen Z. Detection of Chromosome Over- and Underrepresentations in Hyperdiploid Acute Lymphoblastic Leukemia by Comparative Genomic Hybridization Cancer Genetics and Cytogenetics. 103: 20-24. PMID 9595040 DOI: 10.1016/S0165-4608(97)00382-8 |
0.324 |
|
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