Boris Bastian - Publications

Affiliations: 
Pathology and Laboratory Medicine University of California, San Francisco, San Francisco, CA 

122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Cloutier JM, Wang M, Vemula SS, Mirza S, Weier J, Aquino JD, McCalmont TH, LeBoit PE, Bastian BC, Yeh I. Amplification of mutant NRAS in melanocytic tumors with features of Spitz tumors. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 100469. PMID 38467248 DOI: 10.1016/j.modpat.2024.100469  0.621
2024 Lorbeer FK, Rieser G, Goel A, Wang M, Oh A, Yeh I, Bastian BC, Hockemeyer D. Distinct senescence mechanisms restrain progression of dysplastic nevi. Pnas Nexus. 3: pgae041. PMID 38371417 DOI: 10.1093/pnasnexus/pgae041  0.624
2023 Chen L, Chang D, Tandukar B, Deivendran D, Pozniak J, Cruz-Pacheco N, Cho RJ, Cheng J, Yeh I, Marine C, Bastian BC, Ji AL, Shain AH. STmut: a framework for visualizing somatic alterations in spatial transcriptomics data of cancer. Genome Biology. 24: 273. PMID 38037084 DOI: 10.1186/s13059-023-03121-6  0.51
2023 Erdmann-Pham DD, Batra SS, Turkalo TK, Durbin J, Blanchette M, Yeh I, Shain H, Bastian BC, Song YS, Rokhsar DS, Hockemeyer D. Tracing cancer evolution and heterogeneity using Hi-C. Nature Communications. 14: 7111. PMID 37932252 DOI: 10.1038/s41467-023-42651-2  0.524
2023 Wang M, Fukushima S, Sheen YS, Ramelyte E, Pacheco NC, Shi C, Liu S, Banik I, Aquino JD, Acosta MS, Levesque M, Dummer R, Liau JY, Chu CY, Shain AH, ... ... Bastian BC, et al. The genetic evolution of acral melanoma. Biorxiv : the Preprint Server For Biology. PMID 37904969 DOI: 10.1101/2023.10.18.562802  0.654
2023 Lorbeer FK, Rieser G, Goel A, Wang M, Oh A, Yeh I, Bastian BC, Hockemeyer D. Distinct senescence mechanisms restrain progression of dysplastic nevi. Biorxiv : the Preprint Server For Biology. PMID 37503286 DOI: 10.1101/2023.07.14.548818  0.624
2023 Perkins IU, Tan SY, McCalmont TH, Chou PM, Mully TW, Gerami P, Pomerantz JH, Reyes-Múgica M, Balkin DM, Kruse LL, Huang B, Reichek JL, Gangopadhyay N, Chiosea S, Green JR, ... ... Bastian BC, et al. Melanoma in infants, caused by a gene fusion involving the anaplastic lymphoma kinase (ALK). Pigment Cell & Melanoma Research. PMID 37475109 DOI: 10.1111/pcmr.13115  0.627
2023 Fouchardiere A, Pissaloux D, Houlier A, Paindavoine S, Tirode F, LeBoit PE, Bastian BC, Yeh I. Histological and genetic features of 51 Melanocytic Neoplasms with Protein Kinase C fusion genes. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 100286. PMID 37474004 DOI: 10.1016/j.modpat.2023.100286  0.63
2023 Roy SF, Milante R, Pissaloux D, Tirode F, Bastian BC, Fouchardière A, Yeh I. Spectrum of Melanocytic Tumors Harboring BRAF Gene Fusions: 58 Cases With Histomorphologic and Genetic Correlations. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 36: 100149. PMID 36841436 DOI: 10.1016/j.modpat.2023.100149  0.597
2023 Barnhill RL, Elder DE, Piepkorn MW, Knezevich SR, Reisch LM, Eguchi MM, Bastian BC, Blokx W, Bosenberg M, Busam KJ, Carr R, Cochran A, Cook MG, Duncan LM, Elenitsas R, et al. Revision of the Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis Classification Schema for Melanocytic Lesions: A Consensus Statement. Jama Network Open. 6: e2250613. PMID 36630138 DOI: 10.1001/jamanetworkopen.2022.50613  0.485
2022 Wang M, Banik I, Shain AH, Yeh I, Bastian BC. Integrated genomic analyses of acral and mucosal melanomas nominate novel driver genes. Genome Medicine. 14: 65. PMID 35706047 DOI: 10.1186/s13073-022-01068-0  0.599
2021 Robertson SJ, Orme L, Teixeira R, Shamassi M, Newell F, Patch AM, Yeh I, Gard G, Wilmott J, Jackett L, LeBoit P, Fellowes A, MacArthur G, Fox S, Hayward NK, ... Bastian B, et al. Evaluation of Crizotinib Treatment in a Patient With Unresectable GOPC-ROS1 Fusion Agminated Spitz Nevi. Jama Dermatology. PMID 34076666 DOI: 10.1001/jamadermatol.2021.0025  0.543
2021 Roy SF, Bastian BC, Maguiness S, Giubellino A, Vemula S, McCalmont TH, Yeh I. Multiple desmoplastic Spitz nevi with BRAF fusions in a patient with ring chromosome 7 syndrome. Pigment Cell & Melanoma Research. PMID 33522711 DOI: 10.1111/pcmr.12963  0.479
2021 Tang J, Fewings E, Chang D, Zeng H, Liu S, Jorapur A, Belote RL, McNeal AS, Tan TM, Yeh I, Arron ST, Judson-Torres RL, Bastian BC, Shain AH. Publisher Correction: The genomic landscapes of individual melanocytes from human skin. Nature. PMID 33469220 DOI: 10.1038/s41586-020-03105-7  0.488
2020 Ma J, Weng L, Bastian BC, Chen X. Functional characterization of uveal melanoma oncogenes. Oncogene. PMID 33262460 DOI: 10.1038/s41388-020-01569-5  0.317
2020 Tang J, Fewings E, Chang D, Zeng H, Liu S, Jorapur A, Belote RL, McNeal AS, Tan TM, Yeh I, Arron ST, Judson-Torres RL, Bastian BC, Shain AH. The genomic landscapes of individual melanocytes from human skin. Nature. PMID 33029006 DOI: 10.1038/s41586-020-2785-8  0.57
2020 Raghavan SS, Kapler ES, Dinges MM, Bastian BC, Yeh I. Eruptive Spitz nevus, a striking example of benign metastasis. Scientific Reports. 10: 16216. PMID 33004920 DOI: 10.1038/s41598-020-73264-0  0.576
2020 de la Fouchardière A, Tee MK, Peternel S, Valdebran M, Pissaloux D, Tirode F, Busam KJ, LeBoit PE, McCalmont TH, Bastian BC, Yeh I. Fusion partners of NTRK3 affect subcellular localization of the fusion kinase and cytomorphology of melanocytes. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 32968185 DOI: 10.1038/s41379-020-00678-6  0.565
2020 Lee HJ, Pham T, Chang MT, Barnes D, Cai AG, Noubade R, Totpal K, Chen X, Tran C, Hagenbeek T, Wu X, Eastham-Anderson J, Tao J, Lee W, Bastian BC, et al. The tumor suppressor BAP1 regulates the Hippo pathway in pancreatic ductal adenocarcinoma. Cancer Research. PMID 31988076 DOI: 10.1158/0008-5472.Can-19-1704  0.307
2020 Raghavan SS, Peternel S, Mully TW, North JP, Pincus LB, LeBoit PE, McCalmont TH, Bastian BC, Yeh I. Spitz melanoma is a distinct subset of spitzoid melanoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 31900433 DOI: 10.1038/S41379-019-0445-Z  0.667
2020 Natesan D, Martell H, Devine P, Stohr BA, Grenert JP, Van Ziffle J, Joseph NM, Bastian BC, Umetsu SE, Onodera C, Chan E, Desai A, Wong AC, Porten SP, Chou J, et al. Correlation of tumor mutational burden (TMB) with molecular profiling and clinical characteristics in patients with bladder cancer. Journal of Clinical Oncology. 38: e17025-e17025. DOI: 10.1200/Jco.2020.38.15_Suppl.E17025  0.385
2019 Houlier A, Pissaloux D, Masse I, Tirode F, Karanian M, Pincus LB, McCalmont TH, LeBoit PE, Bastian BC, Yeh I, de la Fouchardière A. Melanocytic tumors with MAP3K8 fusions: report of 33 cases with morphological-genetic correlations. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 31719662 DOI: 10.1038/S41379-019-0384-8  0.607
2019 Botton T, Talevich E, Mishra VK, Zhang T, Shain AH, Berquet C, Gagnon A, Judson RL, Ballotti R, Ribas A, Herlyn M, Rocchi S, Brown KM, Hayward NK, Yeh I, ... Bastian BC, et al. Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses. Cell Reports. 29: 573-588.e7. PMID 31618628 DOI: 10.1016/J.Celrep.2019.09.009  0.566
2019 Torres R, Lang UE, Hejna M, Shelton SJ, Joseph NM, Shain AH, Yeh I, Wei ML, Oldham MC, Bastian BC, Judson-Torres RL. MicroRNA ratios distinguish melanomas from nevi. The Journal of Investigative Dermatology. PMID 31580842 DOI: 10.1016/J.Jid.2019.06.126  0.564
2019 Rotow JK, Gui P, Wu W, Raymond VM, Lanman RB, Kaye FJ, Peled N, Fece de la Cruz F, Nadres B, Corcoran RB, Yeh I, Bastian BC, Starostik P, Newsom K, Olivas V, et al. Co-occurring alterations in the RAS-MAPK pathway limit response to MET inhibitor treatment in MET exon 14 skipping mutation-positive lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31548343 DOI: 10.1158/1078-0432.Ccr-19-1667  0.544
2019 Newell F, Kong Y, Wilmott JS, Johansson PA, Ferguson PM, Cui C, Li Z, Kazakoff SH, Burke H, Dodds TJ, Patch AM, Nones K, Tembe V, Shang P, van der Weyden L, ... ... Bastian BC, et al. Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets. Nature Communications. 10: 3163. PMID 31320640 DOI: 10.1038/S41467-019-11107-X  0.662
2019 Tsai KK, Khurana N, McCalmont T, Daud A, Bastian B, Yeh I. PTCH1 Mutation in a Patient With Metastatic Undifferentiated Carcinoma With Clear Cell Change. Journal of the National Comprehensive Cancer Network : Jnccn. 17: 778-783. PMID 31319387 DOI: 10.6004/Jnccn.2019.7313  0.629
2019 Shain AH, Bagger MM, Yu R, Chang D, Liu S, Vemula S, Weier JF, Wadt K, Heegaard S, Bastian BC, Kiilgaard JF. The genetic evolution of metastatic uveal melanoma. Nature Genetics. PMID 31253977 DOI: 10.1038/s41588-019-0440-9  0.42
2019 Yeh I, Busam KJ, McCalmont TH, LeBoit PE, Pissaloux D, Alberti L, de la Fouchardière A, Bastian BC. Filigree-like Rete Ridges, Lobulated Nests, Rosette-like Structures, and Exaggerated Maturation Characterize Spitz Tumors With NTRK1 Fusion. The American Journal of Surgical Pathology. PMID 30844834 DOI: 10.1097/Pas.0000000000001235  0.58
2019 Wong K, van der Weyden L, Schott CR, Foote A, Constantino-Casas F, Smith S, Dobson JM, Murchison EP, Wu H, Yeh I, Fullen DR, Joseph N, Bastian BC, Patel RM, Martincorena I, et al. Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma. Nature Communications. 10: 353. PMID 30664638 DOI: 10.1038/S41467-018-08081-1  0.619
2019 Yeh I, Jorgenson E, Shen L, Xu M, North JP, Shain AH, Reuss D, Wu H, Robinson WA, Olshen A, von Deimling A, Kwok PY, Bastian BC, Asgari MM. Targeted genomic profiling of acral melanoma. Journal of the National Cancer Institute. PMID 30657954 DOI: 10.1093/Jnci/Djz005  0.622
2019 Torres R, Lang U, Joseph N, Shain A, Yeh I, Wei M, Oldham M, Bastian B, Judson-Torres R. 786 A machine-learning classifier trained with microRNA ratios to distinguish melanomas from nevi Journal of Investigative Dermatology. 139: S136. DOI: 10.1016/J.Jid.2019.03.862  0.494
2018 Ablain J, Xu M, Rothschild H, Jordan RC, Mito JK, Daniels BH, Bell CF, Joseph NM, Wu H, Bastian BC, Zon LI, Yeh I. Human tumor genomics and zebrafish modeling identify loss as a driver of mucosal melanoma. Science (New York, N.Y.). PMID 30385465 DOI: 10.1126/Science.Aau6509  0.652
2018 López GY, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Clarke J, Oberheim Bush NA, Taylor J, Chang S, Butowski N, Banerjee A, Mueller S, Kline C, Torkildson J, et al. The genetic landscape of gliomas arising after therapeutic radiation. Acta Neuropathologica. PMID 30196423 DOI: 10.1007/S00401-018-1906-Z  0.606
2018 Stevers M, Rabban JT, Garg K, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Zaloudek C, Solomon DA. Well-differentiated papillary mesothelioma of the peritoneum is genetically defined by mutually exclusive mutations in TRAF7 and CDC42. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 30171198 DOI: 10.1038/S41379-018-0127-2  0.629
2018 Webster JD, Pham TH, Wu X, Hughes NW, Li Z, Totpal K, Lee HJ, Calses PC, Chaurushiya MS, Stawiski EW, Modrusan Z, Chang MT, Tran C, Lee WP, Chalasani S, ... ... Bastian BC, et al. The tumor suppressor BAP1 cooperates with BRAFV600E to promote tumor formation in cutaneous melanoma. Pigment Cell & Melanoma Research. PMID 30156010 DOI: 10.1111/Pcmr.12735  0.362
2018 Phillips JJ, Gong H, Chen K, Joseph NM, van Ziffle J, Bastian BC, Grenert JP, Kline CN, Mueller S, Banerjee A, Nicolaides T, Gupta N, Berger MS, Lee HS, Pekmezci M, et al. The genetic landscape of anaplastic pleomorphic xanthoastrocytoma. Brain Pathology (Zurich, Switzerland). PMID 30051528 DOI: 10.1111/Bpa.12639  0.439
2018 Zeng H, Jorapur A, Shain AH, Lang UE, Torres R, Zhang Y, McNeal AS, Botton T, Lin J, Donne M, Bastian IN, Yu R, North JP, Pincus L, Ruben BS, ... ... Bastian BC, et al. Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation. Cancer Cell. 34: 56-68.e9. PMID 29990501 DOI: 10.1016/J.Ccell.2018.05.014  0.57
2018 Shain AH, Joseph NM, Yu R, Benhamida J, Liu S, Prow T, Ruben B, North J, Pincus L, Yeh I, Judson R, Bastian BC. Genomic and Transcriptomic Analysis Reveals Incremental Disruption of Key Signaling Pathways during Melanoma Evolution. Cancer Cell. 34: 45-55.e4. PMID 29990500 DOI: 10.1016/J.Ccell.2018.06.005  0.621
2018 Pekmezci M, Villanueva-Meyer JE, Goode B, Van Ziffle J, Onodera C, Grenert JP, Bastian BC, Chamyan G, Maher OM, Khatib Z, Kleinschmidt-DeMasters BK, Samuel D, Mueller S, Banerjee A, Clarke JL, et al. The genetic landscape of ganglioglioma. Acta Neuropathologica Communications. 6: 47. PMID 29880043 DOI: 10.1186/S40478-018-0551-Z  0.407
2018 Goode B, Mondal G, Hyun M, Ruiz DG, Lin YH, Van Ziffle J, Joseph NM, Onodera C, Talevich E, Grenert JP, Hewedi IH, Snuderl M, Brat DJ, Kleinschmidt-DeMasters BK, Rodriguez FJ, ... ... Bastian BC, et al. A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. Nature Communications. 9: 810. PMID 29476136 DOI: 10.1038/S41467-018-02826-8  0.624
2018 Torres R, Lang U, Shelton S, Yeniay Y, Joseph N, Shain A, Yeh I, Oldham M, Wei M, Bastian B, Judson R. 1220 MicroRNA signature distinguishing nevi from primary melanoma Journal of Investigative Dermatology. 138: S207. DOI: 10.1016/J.Jid.2018.03.1235  0.563
2017 Goode B, Joseph NM, Stevers M, Van Ziffle J, Onodera C, Talevich E, Grenert JP, Yeh I, Bastian BC, Phillips JJ, Garg K, Rabban JT, Zaloudek C, Solomon DA. Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 29148537 DOI: 10.1038/Modpathol.2017.153  0.607
2017 Foley N, Van Ziffle J, Yu J, Qi Z, Grenert JP, Yeh I, Bastian B, Kogan S, Mannis GN. Acute myeloid leukemia with t(14;21) involving RUNX1 and SYNE2: A novel favorable-risk translocation? Cancer Genetics. 216: 74-78. PMID 29025598 DOI: 10.1016/J.Cancergen.2017.07.002  0.548
2017 Yeh I, Lang UE, Durieux E, Tee MK, Jorapur A, Shain AH, Haddad V, Pissaloux D, Chen X, Cerroni L, Judson RL, LeBoit PE, McCalmont TH, Bastian BC, de la Fouchardière A. Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi. Nature Communications. 8: 644. PMID 28935960 DOI: 10.1038/S41467-017-00758-3  0.58
2017 Shain AH, Bastian BC. Filling the gaps in the genomic catalogue of melanoma subtypes. Pigment Cell & Melanoma Research. PMID 28656717 DOI: 10.1111/pcmr.12612  0.322
2017 Chen X, Wu Q, Depeille P, Chen P, Thornton S, Kalirai H, Coupland SE, Roose JP, Bastian BC. RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma. Cancer Cell. 31: 685-696.e6. PMID 28486107 DOI: 10.1016/j.ccell.2017.04.002  0.309
2017 Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Bloomer M, Campomanes AGA, Banerjee A, ... ... Bastian BC, et al. Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy. Neuro-Oncology. 19: 699-709. PMID 28453743 DOI: 10.1093/Neuonc/Now254  0.541
2017 Korn WM, Yey I, Van Ziffle J, Grenert JP, Joseph N, Solomon DA, Laurance M, Talevich E, Onodera C, Krings G, Stohr BA, Blanco A, Bastian BC. Targeted next-generation DNA sequencing of paired tumor and normal DNA to reveal frequent actionable germline alterations. Journal of Clinical Oncology. 35: 11575-11575. DOI: 10.1200/Jco.2017.35.15_Suppl.11575  0.343
2016 Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Bloomer M, Campomanes AG, Banerjee A, ... ... Bastian BC, et al. Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy. Neuro-Oncology. PMID 27978508 DOI: 10.1093/neuonc/now254  0.541
2016 Joseph NM, Chen YY, Nasr A, Yeh I, Talevich E, Onodera C, Bastian BC, Rabban JT, Garg K, Zaloudek C, Solomon DA. Genomic profiling of malignant peritoneal mesothelioma reveals recurrent alterations in epigenetic regulatory genes BAP1, SETD2, and DDX3X. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 27813512 DOI: 10.1038/Modpathol.2016.188  0.619
2016 Yeh I, Tee MK, Botton T, Hunter Shain A, Sparatta AJ, Gagnon A, Vemula SS, Garrido MC, Nakamaru K, Isoyama T, McCalmont TH, LeBoit PE, Bastian BC. NTRK3 kinase fusions in Spitz tumours. The Journal of Pathology. PMID 27477320 DOI: 10.1002/Path.4775  0.538
2016 Liu SY, Joseph NM, Ravindranathan A, Stohr BA, Greenland NY, Vohra P, Hosfield E, Yeh I, Talevich E, Onodera C, Van Ziffle JA, Grenert JP, Bastian BC, Chen YY, Krings G. Genomic profiling of malignant phyllodes tumors reveals aberrations in FGFR1 and PI-3 kinase/RAS signaling pathways and provides insights into intratumoral heterogeneity. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 27255162 DOI: 10.1038/Modpathol.2016.97  0.637
2016 Kline CN, Joseph NM, Grenert JP, van Ziffle J, Yeh I, Bastian BC, Mueller S, Solomon DA. Inactivating MUTYH germline mutations in pediatric patients with high-grade midline gliomas. Neuro-Oncology. PMID 26902849 DOI: 10.1093/Neuonc/Now013  0.569
2016 Shain AH, Yu R, Yeh I, Benhamida J, Kovalyshyn I, Sriharan A, Talevich E, Dummer R, North J, Pincus L, Ruben B, Rickaby W, D’Arrigo C, Robson A, Judson R, ... ... Bastian B, et al. Abstract 2372: The genetic evolution of melanoma Cancer Research. 76: 2372-2372. DOI: 10.1158/1538-7445.Am2016-2372  0.67
2016 Kline C, Solomon D, Perry A, Bastian B, Joseph N, Phillips J, Tihan T, Yeh I, Van Ziffle J, Grenert J, Bollen A, Mueller S, Banerjee A, Gupta N, Raffel C, et al. TB-02UPFRONT, REAL-TIME TUMOR AND GERMLINE SEQUENCING OF PEDIATRIC BRAIN TUMOR PATIENTS: THE UCSF EXPERIENCE Neuro-Oncology. 18: iii169.2-iii169. DOI: 10.1093/Neuonc/Now084.02  0.571
2015 Shain AH, Yeh I, Kovalyshyn I, Sriharan A, Talevich E, Gagnon A, Dummer R, North J, Pincus L, Ruben B, Rickaby W, D'Arrigo C, Robson A, Bastian BC. The Genetic Evolution of Melanoma from Precursor Lesions. The New England Journal of Medicine. 373: 1926-36. PMID 26559571 DOI: 10.1056/Nejmoa1502583  0.578
2015 Shain AH, Garrido M, Botton T, Talevich E, Yeh I, Sanborn JZ, Chung J, Wang NJ, Kakavand H, Mann GJ, Thompson JF, Wiesner T, Roy R, Olshen AB, Gagnon A, ... ... Bastian BC, et al. Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway. Nature Genetics. PMID 26343386 DOI: 10.1038/Ng.3382  0.637
2015 Sanborn JZ, Chung J, Purdom E, Wang NJ, Kakavand H, Wilmott JS, Butler T, Thompson JF, Mann GJ, Haydu LE, Saw RP, Busam KJ, Lo RS, Collisson EA, Hur JS, ... ... Bastian BC, et al. Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination. Proceedings of the National Academy of Sciences of the United States of America. PMID 26286987 DOI: 10.1073/Pnas.1508074112  0.342
2015 Menzies AM, Yeh I, Botton T, Bastian BC, Scolyer RA, Long GV. Clinical activity of the MEK inhibitor trametinib in metastatic melanoma containing BRAF kinase fusion. Pigment Cell & Melanoma Research. 28: 607-10. PMID 26072686 DOI: 10.1111/Pcmr.12388  0.546
2015 Yeh I, Botton T, Talevich E, Shain AH, Sparatta AJ, de la Fouchardiere A, Mully TW, North JP, Garrido MC, Gagnon A, Vemula SS, McCalmont TH, LeBoit PE, Bastian BC. Activating MET kinase rearrangements in melanoma and Spitz tumours. Nature Communications. 6: 7174. PMID 26013381 DOI: 10.1038/Ncomms8174  0.574
2015 Yeh I, de la Fouchardiere A, Pissaloux D, Mully TW, Garrido MC, Vemula SS, Busam KJ, LeBoit PE, McCalmont TH, Bastian BC. Clinical, histopathologic, and genomic features of Spitz tumors with ALK fusions. The American Journal of Surgical Pathology. 39: 581-91. PMID 25602801 DOI: 10.1097/Pas.0000000000000387  0.597
2015 Shain AH, Garrido M, Botton T, Talevich E, Yeh I, Sanborn Z, Chung J, Wang N, Kakavand H, Mann G, Thompson J, Wiesner T, Roy R, Olshen A, Gagnon A, ... ... Bastian B, et al. Abstract 2968: Exome sequencing of desmoplastic melanoma reveals recurrent NFKBIE promoter mutations and diverse MAPK/PI3K pathway activating mutations Cancer Research. 75: 2968-2968. DOI: 10.1158/1538-7445.Am2015-2968  0.525
2015 Shain AH, Garrido M, Botton T, Talevich E, Yeh I, Sanborn JZ, Chung J, Wang NJ, Kakavand H, Mann GJ, Thompson JF, Wiesner T, Roy R, Olshen AB, Gagnon A, ... ... Bastian BC, et al. Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway Nature Genetics. DOI: 10.1038/ng.3382  0.602
2015 Yeh I, Botton T, Talevich E, Shain AH, Sparatta AJ, De La Fouchardiere A, Mully TW, North JP, Garrido MC, Gagnon A, Vemula SS, McCalmont TH, Leboit PE, Bastian BC. Activating MET kinase rearrangements in melanoma and Spitz tumours Nature Communications. 6. DOI: 10.1038/ncomms8174  0.532
2014 Carvajal R, Lawrence D, Weber JS, Gajewski TF, Gonzalez R, Lutzky J, O'Day S, Hamid O, Wolchok JD, Chapman P, Sullivan RJ, Teitcher JB, Antonescu C, Heinrich MC, Bastian B, et al. 1112PPHASE II STUDY OF NILOTINIB IN MELANOMA HARBORING KIT ALTERATIONS FOLLOWING PROGRESSION OR INTOLERANCE TO PRIOR KIT INHIBITION. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 25: iv385-iv386. PMID 28171268 DOI: 10.1093/Annonc/Mdu344.28  0.315
2014 Botton T, Yeh I, Bastian BC. Melanoma BRAF fusions--letter. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 6631. PMID 25512635 DOI: 10.1158/1078-0432.Ccr-14-0058  0.57
2014 Esteve-Puig R, Gil R, González-Sánchez E, Bech-Serra JJ, Grueso J, Hernández-Losa J, Moliné T, Canals F, Ferrer B, Cortés J, Bastian B, Ramón Y Cajal S, Martín-Caballero J, Flores JM, Vivancos A, et al. A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradation. Plos Genetics. 10: e1004721. PMID 25329316 DOI: 10.1371/Journal.Pgen.1004721  0.361
2014 Yu FX, Luo J, Mo JS, Liu G, Kim YC, Meng Z, Zhao L, Peyman G, Ouyang H, Jiang W, Zhao J, Chen X, Zhang L, Wang CY, Bastian BC, et al. Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP. Cancer Cell. 25: 822-30. PMID 24882516 DOI: 10.1016/J.Ccr.2014.04.017  0.384
2014 Yeh I, Mully TW, Wiesner T, Vemula SS, Mirza SA, Sparatta AJ, McCalmont TH, Bastian BC, LeBoit PE. Ambiguous melanocytic tumors with loss of 3p21. The American Journal of Surgical Pathology. 38: 1088-95. PMID 24705312 DOI: 10.1097/Pas.0000000000000209  0.586
2014 Bastian BC. The molecular pathology of melanoma: an integrated taxonomy of melanocytic neoplasia. Annual Review of Pathology. 9: 239-71. PMID 24460190 DOI: 10.1146/annurev-pathol-012513-104658  0.407
2014 Wiesner T, He J, Yelensky R, Esteve-Puig R, Botton T, Yeh I, Lipson D, Otto G, Brennan K, Murali R, Garrido M, Miller VA, Ross JS, Berger MF, Sparatta A, ... ... Bastian BC, et al. Kinase fusions are frequent in Spitz tumours and spitzoid melanomas. Nature Communications. 5: 3116. PMID 24445538 DOI: 10.1038/Ncomms4116  0.583
2014 Chen X, Wu Q, Tan L, Porter D, Jager MJ, Emery C, Bastian BC. Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations. Oncogene. 33: 4724-34. PMID 24141786 DOI: 10.1038/onc.2013.418  0.388
2014 Simpson RM, Bastian BC, Michael HT, Webster JD, Prasad ML, Conway CM, Prieto VM, Gary JM, Goldschmidt MH, Esplin DG, Smedley RC, Piris A, Meuten DJ, Kiupel M, Lee CC, et al. Sporadic naturally occurring melanoma in dogs as a preclinical model for human melanoma. Pigment Cell & Melanoma Research. 27: 37-47. PMID 24128326 DOI: 10.1111/pcmr.12185  0.32
2013 Botton T, Yeh I, Nelson T, Vemula SS, Sparatta A, Garrido MC, Allegra M, Rocchi S, Bahadoran P, McCalmont TH, LeBoit PE, Burton EA, Bollag G, Ballotti R, Bastian BC. Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy. Pigment Cell & Melanoma Research. 26: 845-51. PMID 23890088 DOI: 10.1111/Pcmr.12148  0.632
2013 Yeh I, von Deimling A, Bastian BC. Clonal BRAF mutations in melanocytic nevi and initiating role of BRAF in melanocytic neoplasia. Journal of the National Cancer Institute. 105: 917-9. PMID 23690527 DOI: 10.1093/Jnci/Djt119  0.589
2013 Murali R, Scolyer R, Bastian B. Skin: Spitz tumors Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/48473  0.426
2013 Stephens P, Wiesner T, He J, Yelensky R, Esteve-Puig R, Otto G, Berger MF, Lipson D, Brennan K, Miller VA, Cronin MT, Bastian BC. Next-generation sequencing of genomic and cDNA to identify a high frequency of kinase fusions involving ROS1, ALK, RET, NTRK1, and BRAF in Spitz tumors. Journal of Clinical Oncology. 31: 9002-9002. DOI: 10.1200/jco.2013.31.15_suppl.9002  0.422
2013 Blakely CM, Lin L, Asthana S, Sidiropoulos N, Nelson T, Bastian BC, Gubens MA, Taylor BS, Bivona TG. Concurrent driver mutations in non-small cell lung cancer (NSCLC) patients (p) on targeted therapy uncovered by comprehensive molecular profiling. Journal of Clinical Oncology. 31: 11004-11004. DOI: 10.1200/Jco.2013.31.15_Suppl.11004  0.316
2012 Wiesner T, Murali R, Fried I, Cerroni L, Busam K, Kutzner H, Bastian BC. A distinct subset of atypical Spitz tumors is characterized by BRAF mutation and loss of BAP1 expression. The American Journal of Surgical Pathology. 36: 818-30. PMID 22367297 DOI: 10.1097/PAS.0b013e3182498be5  0.4
2012 Minor DR, Kashani-Sabet M, Garrido M, O'Day SJ, Hamid O, Bastian BC. Sunitinib therapy for melanoma patients with KIT mutations. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 1457-63. PMID 22261812 DOI: 10.1158/1078-0432.CCR-11-1987  0.359
2012 Griewank KG, Yu X, Khalili J, Sozen MM, Stempke-Hale K, Bernatchez C, Wardell S, Bastian BC, Woodman SE. Genetic and molecular characterization of uveal melanoma cell lines Pigment Cell and Melanoma Research. 25: 182-187. PMID 22236444 DOI: 10.1111/j.1755-148X.2012.00971.x  0.38
2012 Daud A, Bastian BC. Beyond BRAF in melanoma. Current Topics in Microbiology and Immunology. 355: 99-117. PMID 21826607 DOI: 10.1007/82_2011_163  0.33
2012 Yelensky R, Wang K, Dogan S, Borsu L, Frampton G, Lipson D, Stephens P, Bastian B, Klimstra D, Ladanyi M, Cronin MT, Hedvat C, Berger MF. Next-generation sequencing of FFPE solid tumor specimens for clinical use. Journal of Clinical Oncology. 30: 10524-10524. DOI: 10.1200/Jco.2012.30.15_Suppl.10524  0.452
2011 Wiesner T, Obenauf AC, Murali R, Fried I, Griewank KG, Ulz P, Windpassinger C, Wackernagel W, Loy S, Wolf I, Viale A, Lash AE, Pirun M, Socci ND, Rütten A, ... ... Bastian BC, et al. Germline mutations in BAP1 predispose to melanocytic tumors. Nature Genetics. 43: 1018-21. PMID 21874003 DOI: 10.1038/ng.910  0.402
2011 Jalas JR, Vemula S, Bezrookove V, Leboit PE, Simko JP, Bastian BC. Metastatic melanoma with striking adenocarcinomatous differentiation illustrating phenotypic plasticity in melanoma. The American Journal of Surgical Pathology. 35: 1413-8. PMID 21836492 DOI: 10.1097/PAS.0b013e31822280d8  0.428
2011 Carvajal RD, Antonescu CR, Wolchok JD, Chapman PB, Roman RA, Teitcher J, Panageas KS, Busam KJ, Chmielowski B, Lutzky J, Pavlick AC, Fusco A, Cane L, Takebe N, Vemula S, ... ... Bastian BC, et al. KIT as a therapeutic target in metastatic melanoma. Jama. 305: 2327-34. PMID 21642685 DOI: 10.1001/Jama.2011.746  0.301
2011 Bauer J, Büttner P, Murali R, Okamoto I, Kolaitis NA, Landi MT, Scolyer RA, Bastian BC. BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor, and the degree of solar elastosis at the primary tumor site. Pigment Cell & Melanoma Research. 24: 345-51. PMID 21324100 DOI: 10.1111/j.1755-148X.2011.00837.x  0.346
2011 Wiesner T, Obenauf A, Murali R, Fried I, Griewank K, Ulz P, Windpassinger C, Loy S, Wackernagel W, Wolf I, Becker J, Viale A, Lash A, Pirun M, Socci N, ... ... Bastian B, et al. Abstract LB-125: Germline mutations in BAP1 predispose to melanocytic nevi and melanoma Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-125  0.503
2010 Van Raamsdonk CD, Griewank KG, Crosby MB, Garrido MC, Vemula S, Wiesner T, Obenauf AC, Wackernagel W, Green G, Bouvier N, Sozen MM, Baimukanova G, Roy R, Heguy A, Dolgalev I, ... ... Bastian BC, et al. Mutations in GNA11 in uveal melanoma. The New England Journal of Medicine. 363: 2191-9. PMID 21083380 DOI: 10.1056/Nejmoa1000584  0.322
2010 Broekaert SM, Roy R, Okamoto I, van den Oord J, Bauer J, Garbe C, Barnhill RL, Busam KJ, Cochran AJ, Cook MG, Elder DE, McCarthy SW, Mihm MC, Schadendorf D, Scolyer RA, ... ... Bastian BC, et al. Genetic and morphologic features for melanoma classification. Pigment Cell & Melanoma Research. 23: 763-70. PMID 20874733 DOI: 10.1111/j.1755-148X.2010.00778.x  0.312
2010 Flaherty KT, Hodi FS, Bastian BC. Mutation-driven drug development in melanoma Current Opinion in Oncology. 22: 178-183. PMID 20401974 DOI: 10.1097/CCO.0b013e32833888ee  0.339
2010 Gerami P, Pouryazdanparast P, Vemula S, Bastian BC. Molecular analysis of a case of nevus of ota showing progressive evolution to melanoma with intermediate stages resembling cellular blue nevus. The American Journal of Dermatopathology. 32: 301-5. PMID 20110797 DOI: 10.1097/DAD.0b013e3181b96db7  0.364
2010 Fisher DE, Barnhill R, Hodi FS, Herlyn M, Merlino G, Medrano E, Bastian B, Landi MT, Landi TM, Sosman J. Melanoma from bench to bedside: meeting report from the 6th international melanoma congress. Pigment Cell & Melanoma Research. 23: 14-26. PMID 20025711 DOI: 10.1111/J.1755-148X.2009.00655.X  0.313
2010 Garrido MC, Bastian BC. KIT as a therapeutic target in melanoma. The Journal of Investigative Dermatology. 130: 20-7. PMID 19847190 DOI: 10.1038/jid.2009.334  0.325
2010 Minor DR, O'Day S, Kashani-Sabet M, Daud A, Salman Z, Bastian B. Sunitinib therapy for metastatic melanomas with KIT aberrations. Journal of Clinical Oncology. 28: 8545-8545. DOI: 10.1200/Jco.2010.28.15_Suppl.8545  0.441
2010 Algazi AP, Weber JS, Andrews S, Urbas P, Arimura E, Hwang J, Sondak VK, Bastian B, Daud A. A phase I/II trial of DTIC and dasatinib in metastatic melanoma. Journal of Clinical Oncology. 28: 8532-8532. DOI: 10.1200/Jco.2010.28.15_Suppl.8532  0.385
2010 Fisher DE, Barnhill R, Hodi FS, Herlyn M, Merlino G, Medrano E, Bastian B, Landi MT, Sosman J. Melanoma from bench to bedside: Meeting report from the 6th international melanoma congress (Pigment Cell and Melanoma Research (2010) 23, (14-26 )) Pigment Cell and Melanoma Research. 23: 303. DOI: 10.1111/J.1755-148X.2010.00682.X  0.332
2009 Yeh I, Bastian BC. Genome-wide associations studies for melanoma and nevi. Pigment Cell & Melanoma Research. 22: 527-8. PMID 19686382 DOI: 10.1111/J.1755-148X.2009.00622.X  0.555
2009 Bauer J, Kilic E, Vaarwater J, Bastian BC, Garbe C, de Klein A. Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma. British Journal of Cancer. 101: 813-5. PMID 19654573 DOI: 10.1038/sj.bjc.6605226  0.309
2009 Cronin JC, Wunderlich J, Loftus SK, Prickett TD, Wei X, Ridd K, Vemula S, Burrell AS, Agrawal NS, Lin JC, Banister CE, Buckhaults P, Rosenberg SA, Bastian BC, Pavan WJ, et al. Frequent mutations in the MITF pathway in melanoma. Pigment Cell & Melanoma Research. 22: 435-44. PMID 19422606 DOI: 10.1111/J.1755-148X.2009.00578.X  0.399
2009 Gartside MG, Chen H, Ibrahimi OA, Byron SA, Curtis AV, Wellens CL, Bengston A, Yudt LM, Eliseenkova AV, Ma J, Curtin JA, Hyder P, Harper UL, Riedesel E, Mann GJ, ... ... Bastian BC, et al. Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma. Molecular Cancer Research : McR. 7: 41-54. PMID 19147536 DOI: 10.1158/1541-7786.Mcr-08-0021  0.332
2009 Van Raamsdonk CD, Bezrookove V, Green G, Bauer J, Gaugler L, O'Brien JM, Simpson EM, Barsh GS, Bastian BC. Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature. 457: 599-602. PMID 19078957 DOI: 10.1038/nature07586  0.368
2008 Kim RD, Curtin JA, Bastian BC. Lack of somatic alterations of MC1R in primary melanoma. Pigment Cell & Melanoma Research. 21: 579-82. PMID 18761657 DOI: 10.1111/j.1755-148X.2008.00497.x  0.402
2008 Viros A, Fridlyand J, Bauer J, Lasithiotakis K, Garbe C, Pinkel D, Bastian BC. Improving melanoma classification by integrating genetic and morphologic features. Plos Medicine. 5: e120. PMID 18532874 DOI: 10.1371/journal.pmed.0050120  0.332
2008 Fargnoli MC, Fargnoli MC, Pike K, Pfeiffer RM, Tsang S, Rozenblum E, Munroe DJ, Golubeva Y, Calista D, Seidenari S, Massi D, Carli P, Bauer J, Elder DE, Bastian BC, et al. MC1R variants increase risk of melanomas harboring BRAF mutations. The Journal of Investigative Dermatology. 128: 2485-90. PMID 18368129 DOI: 10.1038/jid.2008.67  0.312
2008 Bauer J, Bastian BC. [DNA copy number changes in the diagnosis of melanocytic tumors]. Der Pathologe. 28: 464-73. PMID 17882420 DOI: 10.1007/s00292-007-0944-4  0.347
2008 Curtin JA, Pinkel D, Bastian BC. Absence of PDGFRA mutations in primary melanoma. The Journal of Investigative Dermatology. 128: 488-9. PMID 17762857 DOI: 10.1038/sj.jid.5701036  0.348
2007 Delmas V, Beermann F, Martinozzi S, Carreira S, Ackermann J, Kumasaka M, Denat L, Goodall J, Luciani F, Viros A, Demirkan N, Bastian BC, Goding CR, Larue L. Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development. Genes & Development. 21: 2923-35. PMID 18006687 DOI: 10.1101/gad.450107  0.309
2007 Kebebew E, Weng J, Bauer J, Ranvier G, Clark OH, Duh QY, Shibru D, Bastian B, Griffin A. The prevalence and prognostic value of BRAF mutation in thyroid cancer. Annals of Surgery. 246: 466-70; discussion 4. PMID 17717450 DOI: 10.1097/Sla.0B013E318148563D  0.37
2007 Bauer J, Curtin JA, Pinkel D, Bastian BC. Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations. The Journal of Investigative Dermatology. 127: 179-82. PMID 16888631 DOI: 10.1038/sj.jid.5700490  0.3
2006 Curtin JA, Busam K, Pinkel D, Bastian BC. Somatic activation of KIT in distinct subtypes of melanoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 4340-6. PMID 16908931 DOI: 10.1200/JCO.2006.06.2984  0.35
2006 Landi MT, Bauer J, Pfeiffer RM, Elder DE, Hulley B, Minghetti P, Calista D, Kanetsky PA, Pinkel D, Bastian BC. MC1R germline variants confer risk for BRAF-mutant melanoma. Science (New York, N.Y.). 313: 521-2. PMID 16809487 DOI: 10.1126/science.1127515  0.376
2006 Pollock P, Gartside M, Ibrahimi O, Curtis A, Yudt L, Curtin J, Mann G, Bastian B, Meltzer P, Mohammadi M. Functional characterization of FGFR2 mutations in melanoma reveals multiple mechanisms of inactivation Melanoma Research. 16: S97. DOI: 10.1097/00008390-200609001-00178  0.325
2005 Maldonado JL, Fridlyand J, Bastian BC. RESPONSE: Re: Determinants of BRAF Mutations in Primary Melanomas Jnci Journal of the National Cancer Institute. 97: 402-402. DOI: 10.1093/JNCI/DJI075  0.317
2003 Maldonado JL, Fridlyand J, Patel H, Jain AN, Busam K, Kageshita T, Ono T, Albertson DG, Pinkel D, Bastian BC. Determinants of BRAF mutations in primary melanomas. Journal of the National Cancer Institute. 95: 1878-90. PMID 14679157 DOI: 10.1093/Jnci/Djg123  0.407
2003 Bastian BC, Olshen AB, LeBoit PE, Pinkel D. Classifying melanocytic tumors based on DNA copy number changes. The American Journal of Pathology. 163: 1765-70. PMID 14578177 DOI: 10.1016/S0002-9440(10)63536-5  0.307
2002 Bastian BC. Molecular cytogenetics as a diagnostic tool for typing melanocytic tumors. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 160: 92-9. PMID 12079244  0.306
2002 You MJ, Castrillon DH, Bastian BC, O'Hagan RC, Bosenberg MW, Parsons R, Chin L, DePinho RA. Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 1455-60. PMID 11818530 DOI: 10.1073/Pnas.022632099  0.301
2000 Bastian BC, LeBoit PE, Pinkel D. Mutations and copy number increase of HRAS in Spitz nevi with distinctive histopathological features. The American Journal of Pathology. 157: 967-72. PMID 10980135 DOI: 10.1016/S0002-9440(10)64609-3  0.337
1994 Drepper H, Khler CO, Bastian B, Breuninger H, Brcker E, Ghl J, Groth W, Hermanek P, Hohenberger W, Klmel K, Landthaler M, Lippold A, Peters A, Tilgen W. Prognosevorteil fr definierte Risikogruppen durch die Lymphknotendissektion@@@Improved prognosis for defined risk groups by lymph node dissection. Long-term study of 3616 melanoma patients Hautarzt. 45: 615-622. PMID 7960769 DOI: 10.1007/S001050050138  0.32
1994 Breuninger H, Köhler C, Drepper H, Bastian B, Bröcker EB, Göhl J, Groth W, Hermanek P, Hohenberger W, Lippold A. [Is acrolentiginous melanoma (ALM) more malignant than superficially spreading melanoma (SSM) at a high-risk site? A matched-pair comparison between 113 ALM and SSM within the scope of a multicenter study]. Hautarzt. 45: 529-531. PMID 7960751 DOI: 10.1007/S001050050120  0.334
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