Andrei Seluanov - Publications

Affiliations: 
School of Arts and Sciences University of Rochester, Rochester, NY 
Area:
Molecular Biology, Aging

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Paine PT, Rechsteiner C, Morandini F, Desdín-Micó G, Mrabti C, Parras A, Haghani A, Brooke R, Horvath S, Seluanov A, Gorbunova V, Ocampo A. Initiation phase cellular reprogramming ameliorates DNA damage in the ERCC1 mouse model of premature aging. Frontiers in Aging. 4: 1323194. PMID 38322248 DOI: 10.3389/fragi.2023.1323194  0.312
2021 Zhao Y, Oreskovic E, Zhang Q, Lu Q, Gilman A, Lin YS, He J, Zheng Z, Lu JY, Lee J, Ke Z, Ablaeva J, Sweet MJ, Horvath S, Zhang Z, ... ... Seluanov A, et al. Transposon-triggered innate immune response confers cancer resistance to the blind mole rat. Nature Immunology. PMID 34556881 DOI: 10.1038/s41590-021-01027-8  0.324
2020 Simon M, Emmrich S, Seluanov A, Gorbunova V. A hairy tale: SIRT7 safeguards skin stem cells during aging. The Embo Journal. e106294. PMID 32803757 DOI: 10.15252/Embj.2020106294  0.316
2020 Zhou X, Dou Q, Fan G, Zhang Q, Sanderford M, Kaya A, Johnson J, Karlsson EK, Tian X, Mikhalchenko A, Kumar S, Seluanov A, Zhang ZD, Gorbunova V, Liu X, et al. Beaver and Naked Mole Rat Genomes Reveal Common Paths to Longevity. Cell Reports. 32: 107949. PMID 32726638 DOI: 10.1016/J.Celrep.2020.107949  0.337
2020 Takasugi M, Firsanov D, Tombline G, Ning H, Ablaeva J, Seluanov A, Gorbunova V. Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties. Nature Communications. 11: 2376. PMID 32398747 DOI: 10.1038/S41467-020-16050-W  0.312
2020 Kumar V, Agrawal R, Pandey A, Kopf S, Hoeffgen M, Kaymak S, Bandapalli OR, Gorbunova V, Seluanov A, Mall MA, Herzig S, Nawroth PP. Compromised DNA repair is responsible for diabetes-associated fibrosis. The Embo Journal. e103477. PMID 32338774 DOI: 10.15252/Embj.2019103477  0.316
2019 Tombline G, Gigas J, Macoretta N, Zacher M, Emmrich S, Zhao Y, Seluanov A, Gorbunova V. Proteomics of Long-Lived Mammals. Proteomics. e1800416. PMID 31737995 DOI: 10.1002/Pmic.201800416  0.351
2019 Chen Y, Zhang H, Xu Z, Tang H, Geng A, Cai B, Su T, Shi J, Jiang C, Tian X, Seluanov A, Huang J, Wan X, Jiang Y, Gorbunova V, et al. A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites. Nucleic Acids Research. PMID 31291457 DOI: 10.1093/Nar/Gkz592  0.346
2019 Tian X, Firsanov D, Zhang Z, Cheng Y, Luo L, Tombline G, Tan R, Simon M, Henderson S, Steffan J, Goldfarb A, Tam J, Zheng K, Cornwell A, Johnson A, ... ... Seluanov A, et al. SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Cell. 177: 622-638.e22. PMID 31002797 DOI: 10.1016/J.Cell.2019.03.043  0.396
2019 Simon M, Van Meter M, Ablaeva J, Ke Z, Gonzalez RS, Taguchi T, De Cecco M, Leonova KI, Kogan V, Helfand SL, Neretti N, Roichman A, Cohen HY, Meer MV, Gladyshev VN, ... ... Seluanov A, et al. LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation. Cell Metabolism. PMID 30853213 DOI: 10.1016/J.Cmet.2019.02.014  0.31
2019 De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, ... Seluanov A, et al. L1 drives IFN in senescent cells and promotes age-associated inflammation. Nature. 566: 73-78. PMID 30728521 DOI: 10.1038/S41586-018-0784-9  0.318
2018 Seluanov A, Gladyshev VN, Vijg J, Gorbunova V. Mechanisms of cancer resistance in long-lived mammals. Nature Reviews. Cancer. PMID 29622806 DOI: 10.1038/S41568-018-0004-9  0.326
2018 Zhao Y, Tyshkovskiy A, Muñoz-Espín D, Tian X, Serrano M, de Magalhaes JP, Nevo E, Gladyshev VN, Seluanov A, Gorbunova V. Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence. Proceedings of the National Academy of Sciences of the United States of America. PMID 29432174 DOI: 10.1073/Pnas.1721160115  0.404
2018 Tian X, Doerig K, Park R, Can Ran Qin A, Hwang C, Neary A, Gilbert M, Seluanov A, Gorbunova V. Evolution of telomere maintenance and tumour suppressor mechanisms across mammals. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29335367 DOI: 10.1098/Rstb.2016.0443  0.333
2017 Tan L, Ke Z, Tombline G, Macoretta N, Hayes K, Tian X, Lv R, Ablaeva J, Gilbert M, Bhanu NV, Yuan ZF, Garcia BA, Shi YG, Shi Y, Seluanov A, et al. Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming. Stem Cell Reports. PMID 29107597 DOI: 10.1016/J.Stemcr.2017.10.001  0.335
2017 Piscitello D, Varshney D, Lilla S, Vizioli MG, Reid C, Gorbunova V, Seluanov A, Gillespie DA, Adams PD. AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11. Oncogene. PMID 28967905 DOI: 10.1038/Onc.2017.340  0.391
2017 Tian X, Seluanov A, Gorbunova V. Molecular Mechanisms Determining Lifespan in Short- and Long-Lived Species. Trends in Endocrinology and Metabolism: Tem. PMID 28888702 DOI: 10.1016/J.Tem.2017.07.004  0.353
2017 Ke Z, Mallik P, Johnson AB, Luna F, Nevo E, Zhang ZD, Gladyshev VN, Seluanov A, Gorbunova V. Translation fidelity coevolves with longevity. Aging Cell. PMID 28707419 DOI: 10.1111/Acel.12628  0.307
2017 Tian X, Seluanov A, Gorbunova V. Beyond Making Ends Meet: DNA-PK, Metabolism, and Aging. Cell Metabolism. 25: 991-992. PMID 28467943 DOI: 10.1016/J.Cmet.2017.04.022  0.361
2017 Valenzano DR, Aboobaker A, Seluanov A, Gorbunova V. Non-canonical aging model systems and why we need them. The Embo Journal. PMID 28320740 DOI: 10.15252/Embj.201796837  0.305
2016 Ma S, Upneja A, Galecki A, Tsai YM, Burant CF, Raskind S, Zhang Q, Zhang ZD, Seluanov A, Gorbunova V, Clish CB, Miller RA, Gladyshev VN. Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity. Elife. 5. PMID 27874830 DOI: 10.7554/Elife.19130  0.35
2016 Van Meter M, Simon M, Tombline G, May A, Morello TD, Hubbard BP, Bredbenner K, Park R, Sinclair DA, Bohr VA, Gorbunova V, Seluanov A. JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks. Cell Reports. PMID 27568560 DOI: 10.1016/J.Celrep.2016.08.006  0.356
2016 Hewitt G, Carroll B, Sarallah R, Correia-Melo C, Ogrodnik M, Nelson G, Otten EG, Manni D, Antrobus R, Morgan BA, von Zglinicki T, Jurk D, Seluanov A, Gorbunova V, Johansen T, et al. SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. Autophagy. 0. PMID 27391408 DOI: 10.1080/15548627.2016.1210368  0.398
2016 Gorbunova V, Seluanov A. DNA double strand break repair, aging and the chromatin connection. Mutation Research. 788: 2-6. PMID 26923716 DOI: 10.1016/J.Mrfmmm.2016.02.004  0.391
2016 Ma S, Upneja A, Galecki A, Tsai Y, Burant CF, Raskind S, Zhang Q, Zhang ZD, Seluanov A, Gorbunova V, Clish CB, Miller RA, Gladyshev VN. Author response: Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity Elife. DOI: 10.7554/Elife.19130.019  0.351
2015 MacRae SL, Croken MM, Calder RB, Aliper A, Milholland B, White RR, Zhavoronkov A, Gladyshev VN, Seluanov A, Gorbunova V, Zhang ZD, Vijg J. DNA repair in species with extreme lifespan differences. Aging. PMID 26729707  0.306
2015 MacRae SL, Zhang Q, Lemetre C, Seim I, Calder RB, Hoeijmakers J, Suh Y, Gladyshev VN, Seluanov A, Gorbunova V, Vijg J, Zhang ZD. Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human. Aging Cell. 14: 288-91. PMID 25645816 DOI: 10.1111/Acel.12314  0.356
2015 Xu Z, Zhang L, Zhang W, Meng D, Zhang H, Jiang Y, Xu X, Van Meter M, Seluanov A, Gorbunova V, Mao Z. SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner. Cell Cycle (Georgetown, Tex.). 14: 269-76. PMID 25607651 DOI: 10.4161/15384101.2014.980641  0.385
2015 Tian X, Azpurua J, Ke Z, Augereau A, Zhang ZD, Vijg J, Gladyshev VN, Gorbunova V, Seluanov A. INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform. Proceedings of the National Academy of Sciences of the United States of America. 112: 1053-8. PMID 25550505 DOI: 10.1073/Pnas.1418203112  0.322
2014 Van Meter M, Kashyap M, Rezazadeh S, Geneva AJ, Morello TD, Seluanov A, Gorbunova V. SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age. Nature Communications. 5: 5011. PMID 25247314 DOI: 10.1038/Ncomms6011  0.342
2014 Keane M, Craig T, Alföldi J, Berlin AM, Johnson J, Seluanov A, Gorbunova V, Di Palma F, Lindblad-Toh K, Church GM, de Magalhães JP. The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations. Bioinformatics (Oxford, England). 30: 3558-60. PMID 25172923 DOI: 10.1093/Bioinformatics/Btu579  0.307
2014 Vaidya A, Mao Z, Tian X, Spencer B, Seluanov A, Gorbunova V. Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with age. Plos Genetics. 10: e1004511. PMID 25033455 DOI: 10.1371/Journal.Pgen.1004511  0.395
2014 Van Meter M, Gorbunova V, Seluanov A. SIRT6: a promising target for cancer prevention and therapy. Advances in Experimental Medicine and Biology. 818: 181-96. PMID 25001537 DOI: 10.1007/978-1-4471-6458-6_9  0.307
2014 Gorbunova V, Seluanov A, Zhang Z, Gladyshev VN, Vijg J. Comparative genetics of longevity and cancer: insights from long-lived rodents. Nature Reviews. Genetics. 15: 531-40. PMID 24981598 DOI: 10.1038/Nrg3728  0.328
2014 Fang X, Nevo E, Han L, Levanon EY, Zhao J, Avivi A, Larkin D, Jiang X, Feranchuk S, Zhu Y, Fishman A, Feng Y, Sher N, Xiong Z, Hankeln T, ... ... Seluanov A, et al. Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax. Nature Communications. 5: 3966. PMID 24892994 DOI: 10.1038/Ncomms4966  0.324
2014 Hine CM, Li H, Xie L, Mao Z, Seluanov A, Gorbunova V. Regulation of Rad51 promoter. Cell Cycle (Georgetown, Tex.). 13: 2038-45. PMID 24781030 DOI: 10.4161/Cc.29016  0.388
2014 Cao Y, Xu Y, Zhang L, Li Z, Jiang Y, Tian X, Seluanov A, Gorbunova V, Mao Z. Utilization of Rad51C promoter for transcriptional targeting of cancer cells. Oncotarget. 5: 1805-11. PMID 24742710 DOI: 10.18632/Oncotarget.1792  0.36
2013 Azpurua J, Ke Z, Chen IX, Zhang Q, Ermolenko DN, Zhang ZD, Gorbunova V, Seluanov A. Naked mole-rat has increased translational fidelity compared with the mouse, as well as a unique 28S ribosomal RNA cleavage. Proceedings of the National Academy of Sciences of the United States of America. 110: 17350-5. PMID 24082110 DOI: 10.1073/Pnas.1313473110  0.305
2013 Tian X, Azpurua J, Hine C, Vaidya A, Myakishev-Rempel M, Ablaeva J, Mao Z, Nevo E, Gorbunova V, Seluanov A. High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat. Nature. 499: 346-9. PMID 23783513 DOI: 10.1038/Nature12234  0.333
2012 Azpurua J, Seluanov A. Long-lived cancer-resistant rodents as new model species for cancer research. Frontiers in Genetics. 3: 319. PMID 23316215 DOI: 10.3389/Fgene.2012.00319  0.363
2012 Van Meter M, Seluanov A, Gorbunova V.  Forever young?  Exploring the link between rapamycin, longevity and cancer. Cell Cycle (Georgetown, Tex.). 11: 4296-7. PMID 23152185 DOI: 10.4161/Cc.22868  0.338
2012 Gorbunova V, Hine C, Tian X, Ablaeva J, Gudkov AV, Nevo E, Seluanov A. Cancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanism. Proceedings of the National Academy of Sciences of the United States of America. 109: 19392-6. PMID 23129611 DOI: 10.1073/Pnas.1217211109  0.369
2012 Mao Z, Tian X, Van Meter M, Ke Z, Gorbunova V, Seluanov A. Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence. Proceedings of the National Academy of Sciences of the United States of America. 109: 11800-5. PMID 22753495 DOI: 10.1073/Pnas.1200583109  0.452
2012 Hine CM, Seluanov A, Gorbunova V. Rad51 promoter-targeted gene therapy is effective for in vivo visualization and treatment of cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 347-55. PMID 22008909 DOI: 10.1038/Mt.2011.215  0.308
2011 Fong V, Osterbur M, Capella C, Kim YE, Hine C, Gorbunova V, Seluanov A, Dewhurst S. Adenoviral vector driven by a minimal Rad51 promoter is selective for p53-deficient tumor cells. Plos One. 6: e28714. PMID 22174876 DOI: 10.1371/Journal.Pone.0028714  0.351
2011 Van Meter M, Mao Z, Gorbunova V, Seluanov A. SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells. Cell Cycle (Georgetown, Tex.). 10: 3153-8. PMID 21900744 DOI: 10.4161/Cc.10.18.17435  0.366
2011 Mao Z, Hine C, Tian X, Van Meter M, Au M, Vaidya A, Seluanov A, Gorbunova V. SIRT6 promotes DNA repair under stress by activating PARP1. Science (New York, N.Y.). 332: 1443-6. PMID 21680843 DOI: 10.1126/Science.1202723  0.36
2010 Seluanov A, Vaidya A, Gorbunova V. Establishing primary adult fibroblast cultures from rodents. Journal of Visualized Experiments : Jove. PMID 20972406 DOI: 10.3791/2033  0.337
2010 Seluanov A, Mao Z, Gorbunova V. Analysis of DNA double-strand break (DSB) repair in mammalian cells. Journal of Visualized Experiments : Jove. PMID 20864925 DOI: 10.3791/2002  0.391
2009 Seluanov A, Hine C, Azpurua J, Feigenson M, Bozzella M, Mao Z, Catania KC, Gorbunova V. Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat. Proceedings of the National Academy of Sciences of the United States of America. 106: 19352-7. PMID 19858485 DOI: 10.1073/Pnas.0905252106  0.322
2009 Mao Z, Jiang Y, Liu X, Seluanov A, Gorbunova V. DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells. Neoplasia (New York, N.Y.). 11: 683-91. PMID 19568413 DOI: 10.1593/Neo.09312  0.352
2009 Gorbunova V, Seluanov A. Coevolution of telomerase activity and body mass in mammals: from mice to beavers. Mechanisms of Ageing and Development. 130: 3-9. PMID 18387652 DOI: 10.1016/J.Mad.2008.02.008  0.365
2008 Gorbunova V, Bozzella MJ, Seluanov A. Rodents for comparative aging studies: from mice to beavers. Age (Dordrecht, Netherlands). 30: 111-9. PMID 19424861 DOI: 10.1007/S11357-008-9053-4  0.351
2008 Hine CM, Seluanov A, Gorbunova V. Use of the Rad51 promoter for targeted anti-cancer therapy. Proceedings of the National Academy of Sciences of the United States of America. 105: 20810-5. PMID 19106292 DOI: 10.1073/Pnas.0807990106  0.351
2008 Seluanov A, Hine C, Bozzella M, Hall A, Sasahara TH, Ribeiro AA, Catania KC, Presgraves DC, Gorbunova V. Distinct tumor suppressor mechanisms evolve in rodent species that differ in size and lifespan. Aging Cell. 7: 813-23. PMID 18778411 DOI: 10.1111/J.1474-9726.2008.00431.X  0.36
2008 Mao Z, Bozzella M, Seluanov A, Gorbunova V. DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells. Cell Cycle (Georgetown, Tex.). 7: 2902-6. PMID 18769152 DOI: 10.4161/Cc.7.18.6679  0.371
2008 Mao Z, Bozzella M, Seluanov A, Gorbunova V. Comparison of nonhomologous end joining and homologous recombination in human cells. Dna Repair. 7: 1765-71. PMID 18675941 DOI: 10.1016/J.Dnarep.2008.06.018  0.374
2008 Dion V, Lin Y, Price BA, Fyffe SL, Seluanov A, Gorbunova V, Wilson JH. Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination. Dna Repair. 7: 313-20. PMID 18083071 DOI: 10.1016/J.Dnarep.2007.11.002  0.34
2007 Gorbunova V, Seluanov A, Mao Z, Hine C. Changes in DNA repair during aging. Nucleic Acids Research. 35: 7466-74. PMID 17913742 DOI: 10.1093/Nar/Gkm756  0.392
2007 Seluanov A, Danek J, Hause N, Gorbunova V. Changes in the level and distribution of Ku proteins during cellular senescence. Dna Repair. 6: 1740-8. PMID 17686666 DOI: 10.1016/J.Dnarep.2007.06.010  0.404
2007 Mao Z, Seluanov A, Jiang Y, Gorbunova V. TRF2 is required for repair of nontelomeric DNA double-strand breaks by homologous recombination. Proceedings of the National Academy of Sciences of the United States of America. 104: 13068-73. PMID 17670947 DOI: 10.1073/Pnas.0702410104  0.35
2007 Seluanov A, Chen Z, Hine C, Sasahara TH, Ribeiro AA, Catania KC, Presgraves DC, Gorbunova V. Telomerase activity coevolves with body mass not lifespan. Aging Cell. 6: 45-52. PMID 17173545 DOI: 10.1111/J.1474-9726.2006.00262.X  0.353
2007 Shi X, Seluanov A, Gorbunova V. Cell divisions are required for L1 retrotransposition. Molecular and Cellular Biology. 27: 1264-70. PMID 17145770 DOI: 10.1128/Mcb.01888-06  0.355
2005 Gorbunova V, Seluanov A. Making ends meet in old age: DSB repair and aging. Mechanisms of Ageing and Development. 126: 621-8. PMID 15888314 DOI: 10.1016/J.Mad.2005.02.008  0.401
2004 Gorbunova V, Seluanov A, Mittelman D, Wilson JH. Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalian cells. Human Molecular Genetics. 13: 2979-89. PMID 15459182 DOI: 10.1093/Hmg/Ddh317  0.365
2004 Seluanov A, Mittelman D, Pereira-Smith OM, Wilson JH, Gorbunova V. DNA end joining becomes less efficient and more error-prone during cellular senescence. Proceedings of the National Academy of Sciences of the United States of America. 101: 7624-9. PMID 15123826 DOI: 10.1073/Pnas.0400726101  0.447
2003 Gorbunova V, Seluanov A. Telomerase as a growth-promoting factor. Cell Cycle (Georgetown, Tex.). 2: 534-7. PMID 14504469 DOI: 10.4161/Cc.2.6.515  0.344
2003 Gorbunova V, Seluanov A, Dion V, Sandor Z, Meservy JL, Wilson JH. Selectable system for monitoring the instability of CTG/CAG triplet repeats in mammalian cells. Molecular and Cellular Biology. 23: 4485-93. PMID 12808091 DOI: 10.1128/Mcb.23.13.4485-4493.2003  0.325
2003 Gorbunova V, Seluanov A, Pereira-Smith OM. Evidence that high telomerase activity may induce a senescent-like growth arrest in human fibroblasts. The Journal of Biological Chemistry. 278: 7692-8. PMID 12496279 DOI: 10.1074/Jbc.M212944200  0.359
2002 Gorbunova V, Seluanov A, Pereira-Smith OM. Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis. The Journal of Biological Chemistry. 277: 38540-9. PMID 12140282 DOI: 10.1074/Jbc.M202671200  0.371
2002 Gorbunova V, Seluanov A. CLK-1 protein has DNA binding activity specific to O(L) region of mitochondrial DNA. Febs Letters. 516: 279-84. PMID 11959146 DOI: 10.1016/S0014-5793(02)02568-1  0.338
2001 Seluanov A, Gorbunova V, Falcovitz A, Sigal A, Milyavsky M, Zurer I, Shohat G, Goldfinger N, Rotter V. Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53. Molecular and Cellular Biology. 21: 1552-64. PMID 11238892 DOI: 10.1128/Mcb.21.5.1552-1564.2001  0.351
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