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Ken Kron, Ph.D. - Publications

Affiliations: 
2012 Laboratory Medicine and Pathobiology University of Toronto, Toronto, ON, Canada 
Area:
Oncology, Genetics, Molecular Biology
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Grillo G, Keshavarzian T, Linder S, Arlidge C, Mout L, Nand A, Teng M, Qamra A, Zhou S, Kron KJ, Murison A, Hawley JR, Fraser M, van der Kwast TH, Raj GV, et al. Transposable elements are co-opted as oncogenic regulatory elements by lineage-specific transcription factors in prostate cancer. Cancer Discovery. PMID 37694973 DOI: 10.1158/2159-8290.CD-23-0331  0.803
2021 Hawley JR, Zhou S, Arlidge C, Grillo G, Kron KJ, Hugh-White R, van der Kwast TH, Fraser M, Boutros PC, Bristow RG, Lupien M. Reorganization of the 3D genome pinpoints non-coding drivers of primary prostate tumors. Cancer Research. PMID 34642184 DOI: 10.1158/0008-5472.CAN-21-2056  0.803
2020 Takayama N, Murison A, Takayanagi SI, Arlidge C, Zhou S, Garcia-Prat L, Chan-Seng-Yue M, Zandi S, Gan OI, Boutzen H, Kaufmann KB, Trotman-Grant A, Schoof E, Kron K, Díaz N, et al. The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization. Cell Stem Cell. PMID 33242413 DOI: 10.1016/j.stem.2020.11.001  0.743
2020 Zhou S, Hawley JR, Soares F, Grillo G, Teng M, Madani Tonekaboni SA, Hua JT, Kron KJ, Mazrooei P, Ahmed M, Arlidge C, Yun HY, Livingstone J, Huang V, Yamaguchi TN, et al. Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer. Nature Communications. 11: 441. PMID 31974375 DOI: 10.1038/S41467-020-14318-9  0.773
2019 Mazrooei P, Kron KJ, Zhu Y, Zhou S, Grillo G, Mehdi T, Ahmed M, Severson TM, Guilhamon P, Armstrong NS, Huang V, Yamaguchi TN, Fraser M, van der Kwast T, Boutros PC, et al. Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors. Cancer Cell. PMID 31735626 DOI: 10.1016/J.Ccell.2019.10.005  0.766
2019 Sinha A, Huang V, Livingstone J, Wang J, Fox NS, Kurganovs N, Ignatchenko V, Fritsch K, Donmez N, Heisler LE, Shiah YJ, Yao CQ, Alfaro JA, Volik S, Lapuk A, ... ... Kron K, et al. The Proteogenomic Landscape of Curable Prostate Cancer. Cancer Cell. 35: 414-427.e6. PMID 30889379 DOI: 10.1016/J.Ccell.2019.02.005  0.749
2018 Sonzogni O, Haynes J, Seifried LA, Kamel YM, Huang K, BeGora MD, Yeung FA, Robert-Tissot C, Heng YJ, Yuan X, Wulf GM, Kron KJ, Wagenblast E, Lupien M, Kislinger T, et al. Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo. Plos Biology. 16: e2004049. PMID 29924804 DOI: 10.1371/Journal.Pbio.2004049  0.545
2017 Kron KJ, Murison A, Zhou S, Huang V, Yamaguchi TN, Shiah YJ, Fraser M, van der Kwast T, Boutros PC, Bristow RG, Lupien M. TMPRSS2-ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer. Nature Genetics. PMID 28783165 DOI: 10.1038/Ng.3930  0.779
2017 Olkhov-Mitsel E, Siadat F, Kron K, Liu L, Savio AJ, Trachtenberg J, Fleshner N, van der Kwast T, Bapat B. Distinct DNA methylation alterations are associated with cribriform architecture and intraductal carcinoma in Gleason pattern 4 prostate tumors. Oncology Letters. 14: 390-396. PMID 28693181 DOI: 10.3892/Ol.2017.6140  0.657
2017 Olkhov-Mitsel E, Savio AJ, Kron KJ, Pethe VV, Hermanns T, Fleshner NE, van Rhijn BW, van der Kwast TH, Zlotta AR, Bapat B. Epigenome-Wide DNA Methylation Profiling Identifies Differential Methylation Biomarkers in High-Grade Bladder Cancer. Translational Oncology. 10: 168-177. PMID 28167242 DOI: 10.1016/J.Tranon.2017.01.001  0.596
2017 Fraser M, Sabelnykova VY, Yamaguchi TN, Heisler LE, Livingstone J, Huang V, Shiah YJ, Yousif F, Lin X, Masella AP, Fox NS, Xie M, Prokopec SD, Berlin A, Lalonde E, ... ... Kron K, et al. Genomic hallmarks of localized, non-indolent prostate cancer. Nature. PMID 28068672 DOI: 10.1038/Nature20788  0.795
2016 Bailey SD, Desai K, Kron KJ, Mazrooei P, Sinnott-Armstrong NA, Treloar AE, Dowar M, Thu KL, Cescon DW, Silvester J, Yang SY, Wu X, Pezo RC, Haibe-Kains B, Mak TW, et al. Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer. Nature Genetics. PMID 27571262 DOI: 10.1038/Ng.3650  0.731
2016 Inoue S, Li WY, Tseng A, Beerman I, Elia AJ, Bendall SC, Lemonnier F, Kron KJ, Cescon DW, Hao Z, Lind EF, Takayama N, Planello AC, Shen SY, Shih AH, et al. Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2. Cancer Cell. PMID 27424808 DOI: 10.1016/J.Ccell.2016.05.018  0.534
2016 Kamdar SN, Ho LT, Kron KJ, Isserlin R, van der Kwast T, Zlotta AR, Fleshner NE, Bader G, Bapat B. Dynamic interplay between locus-specific DNA methylation and hydroxymethylation regulates distinct biological pathways in prostate carcinogenesis. Clinical Epigenetics. 8: 32. PMID 26981160 DOI: 10.1186/S13148-016-0195-4  0.722
2016 Planello AC, Singhania R, Kron KJ, Bailey SD, Roulois D, Lupien M, Line SR, de Souza AP, De Carvalho DD. Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation. Oncotarget. PMID 26908456 DOI: 10.18632/Oncotarget.7513  0.739
2015 Olkhov-Mitsel E, Siadat F, Trudel D, Kron K, Liu l, Fleshner NE, Van der Kwast T, Bapat B. MP6-14 DNA METHYLATION ABERRATIONS IN GLEASON PATTERN 4 PROSTATIC CARCINOMA WITH CRIBRIFORM ARCHITECTURE OR INTRADUCTAL CARCINOMA: A RADICAL PROSTATECTOMY STUDY Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.261  0.631
2015 Savio A, Olkhov-Mitsel E, Kron K, Hermanns T, van Rhijn B, Zlotta A, van der Kwast T, Bapat B. MP68-06 TISSUE-BASED DNA METHYLATION PROFILING ESTABLISHES A NOVEL PANEL OF BIOMARKERS FOR DISCRIMINATION OF HIGH-GRADE VERSUS LOW-GRADE BLADDER CANCER Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2468  0.624
2014 Kron KJ, Bailey SD, Lupien M. Enhancer alterations in cancer: a source for a cell identity crisis. Genome Medicine. 6: 77. PMID 25473436 DOI: 10.1186/S13073-014-0077-3  0.757
2014 White-Al Habeeb NM, Ho LT, Olkhov-Mitsel E, Kron K, Pethe V, Lehman M, Jovanovic L, Fleshner N, van der Kwast T, Nelson CC, Bapat B. Integrated analysis of epigenomic and genomic changes by DNA methylation dependent mechanisms provides potential novel biomarkers for prostate cancer. Oncotarget. 5: 7858-69. PMID 25277202 DOI: 10.18632/Oncotarget.2313  0.685
2014 Antignano F, Burrows K, Hughes MR, Han JM, Kron KJ, Penrod NM, Oudhoff MJ, Wang SK, Min PH, Gold MJ, Chenery AL, Braam MJ, Fung TC, Rossi FM, McNagny KM, et al. Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation. The Journal of Clinical Investigation. 124: 1945-55. PMID 24667637 DOI: 10.1172/Jci69592  0.513
2014 Olkhov-Mitsel E, Zdravic D, Kron K, van der Kwast T, Fleshner N, Bapat B. Novel multiplex MethyLight protocol for detection of DNA methylation in patient tissues and bodily fluids. Scientific Reports. 4: 4432. PMID 24651255 DOI: 10.1038/Srep04432  0.629
2014 Saraon P, Trudel D, Kron K, Dmitromanolakis A, Trachtenberg J, Bapat B, van der Kwast T, Jarvi KA, Diamandis EP. Evaluation and prognostic significance of ACAT1 as a marker of prostate cancer progression. The Prostate. 74: 372-80. PMID 24311408 DOI: 10.1002/Pros.22758  0.706
2013 Kron K, Trudel D, Pethe V, Briollais L, Fleshner N, van der Kwast T, Bapat B. Altered DNA methylation landscapes of polycomb-repressed loci are associated with prostate cancer progression and ERG oncogene expression in prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3450-61. PMID 23549870 DOI: 10.1158/1078-0432.Ccr-12-3139  0.739
2013 Olkhov-Mitsel E, Kwast TVd, Kron K, Ozcelik H, Briollais L, Fleshner N, Diamandis E, Zlotta A, Bapat B. Abstract B21: Epigenetic and post-transcriptional regulation of the kallikrein gene family as a novel panel of prostate cancer biomarkers Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-B21  0.521
2012 Olkhov-Mitsel E, Van der Kwast T, Kron KJ, Ozcelik H, Briollais L, Massey C, Recker F, Kwiatkowski M, Fleshner NE, Diamandis EP, Zlotta AR, Bapat B. Quantitative DNA methylation analysis of genes coding for kallikrein-related peptidases 6 and 10 as biomarkers for prostate cancer. Epigenetics : Official Journal of the Dna Methylation Society. 7: 1037-45. PMID 22874102 DOI: 10.4161/epi.21524  0.622
2012 Kron K, Liu L, Trudel D, Pethe V, Trachtenberg J, Fleshner N, Bapat B, van der Kwast T. Correlation of ERG expression and DNA methylation biomarkers with adverse clinicopathologic features of prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 2896-904. PMID 22452941 DOI: 10.1158/1078-0432.Ccr-11-2901  0.709
2012 Olkhov E, Van Der Kwast T, Kron K, Pethe V, Ozcelik H, Briollais L, Fleshner N, Diamandis E, Zlotta A, Bapat B. 543 Methylation of Kallikrein-related peptidases as novel diagnostic and prognostic biomarkers for prostate cancer European Urology Supplements. 11: e543-e543a. DOI: 10.1016/S1569-9056(12)60540-5  0.537
2011 Liu L, Kron KJ, Pethe VV, Demetrashvili N, Nesbitt ME, Trachtenberg J, Ozcelik H, Fleshner NE, Briollais L, van der Kwast TH, Bapat B. Association of tissue promoter methylation levels of APC, TGFβ2, HOXD3 and RASSF1A with prostate cancer progression. International Journal of Cancer. Journal International Du Cancer. 129: 2454-62. PMID 21207416 DOI: 10.1002/Ijc.25908  0.616
2010 Demetrashvili N, Kron K, Pethe V, Bapat B, Briollais L. How to Deal with Batch Effect in Sequential Microarray Experiments? Molecular Informatics. 29: 387-93. PMID 27463194 DOI: 10.1002/Minf.200900019  0.491
2010 Kron KJ, Liu L, Pethe VV, Demetrashvili N, Nesbitt ME, Trachtenberg J, Ozcelik H, Fleshner NE, Briollais L, van der Kwast TH, Bapat B. DNA methylation of HOXD3 as a marker of prostate cancer progression. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 1060-7. PMID 20212450 DOI: 10.1038/Labinvest.2010.57  0.632
2009 Kron K, Pethe V, Briollais L, Sadikovic B, Ozcelik H, Sunderji A, Venkateswaran V, Pinthus J, Fleshner N, van der Kwast T, Bapat B. Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays. Plos One. 4: e4830. PMID 19283074 DOI: 10.1371/Journal.Pone.0004830  0.728
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