| Year |
Citation |
Score |
| 2023 |
Machado-Vieira R, Courtes AC, Zarate CA, Henter ID, Manji HK. Non-canonical pathways in the pathophysiology and therapeutics of bipolar disorder. Frontiers in Neuroscience. 17: 1228455. PMID 37592949 DOI: 10.3389/fnins.2023.1228455 |
0.379 |
|
| 2020 |
Ness S, Pandina G, Jagannatha S, Wathen K, Bangerter A, Manyakov NV, Hendren R, Leventhal B, Murphy D, Dawson G, Drevets WC, Manji HK. ASPI: a public-private partnership to develop treatments for autism. Nature Reviews. Drug Discovery. 19: 219-220. PMID 32242150 DOI: 10.1038/D41573-020-00012-4 |
0.361 |
|
| 2019 |
Popova V, Daly EJ, Trivedi M, Cooper K, Lane R, Lim P, Mazzucco C, Hough D, Thase ME, Shelton RC, Molero P, Vieta E, Bajbouj M, Manji H, Drevets WC, et al. Efficacy and Safety of Flexibly Dosed Esketamine Nasal Spray Combined With a Newly Initiated Oral Antidepressant in Treatment-Resistant Depression: A Randomized Double-Blind Active-Controlled Study. The American Journal of Psychiatry. appiajp201919020172. PMID 31109201 DOI: 10.1176/Appi.Ajp.2019.19020172 |
0.332 |
|
| 2018 |
Ochs-Ross R, Daly EJ, Zhang Y, Lane R, Lim P, Foster K, Hough D, Manji H, Drevets WC, Sanacora G, Adler C, McShane R, Gaillard R, Singh JB. S114. Efficacy and Safety of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Patients With Treatment-Resistant Depression Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.1005 |
0.31 |
|
| 2018 |
Popova V, Daly E, Trivedi M, Cooper K, Lane R, Lim P, Mazzucco C, Hough D, Thase M, Shelton R, Molero P, Vieta E, Bajbouj M, Manji H, Drevets W, et al. S111. Randomized, Double-Blind Study of Flexibly-Dosed Intranasal Esketamine Plus Oral Antidepressant Vs. Active Control in Treatment-Resistant Depression Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.1002 |
0.306 |
|
| 2017 |
Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao WN, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia CD, Yamashita N, Wada M, Inoue Y, Nakamura F, ... ... Manji H, et al. Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28500272 DOI: 10.1073/Pnas.1700111114 |
0.424 |
|
| 2016 |
Breen G, Li Q, Roth BL, O'Donnell P, Didriksen M, Dolmetsch R, O'Reilly PF, Gaspar HA, Manji H, Huebel C, Kelsoe JR, Malhotra D, Bertolino A, Posthuma D, Sklar P, et al. Translating genome-wide association findings into new therapeutics for psychiatry. Nature Neuroscience. 19: 1392-1396. PMID 27786187 DOI: 10.1038/Nn.4411 |
0.319 |
|
| 2016 |
Singh JB, Fedgchin M, Daly EJ, De Boer P, Cooper K, Lim P, Pinter C, Murrough JW, Sanacora G, Shelton RC, Kurian B, Winokur A, Fava M, Manji H, Drevets WC, et al. A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression. The American Journal of Psychiatry. appiajp201616010037. PMID 27056608 DOI: 10.1176/Appi.Ajp.2016.16010037 |
0.324 |
|
| 2016 |
Zarate CA, Quiroz J, Payne J, Manji HK. Modulators of the glutamatergic system: implications for the development of improved therapeutics in mood disorders. Psychopharmacology Bulletin. 36: 35-83. PMID 12858143 |
0.344 |
|
| 2015 |
Bredt DS, Furey ML, Chen G, Lovenberg T, Drevets WC, Manji HK. Translating depression biomarkers for improved targeted therapies. Neuroscience and Biobehavioral Reviews. PMID 26432926 DOI: 10.1016/j.neubiorev.2015.09.013 |
0.324 |
|
| 2015 |
Schubert CR, O'Donnell P, Quan J, Wendland JR, Xi HS, Winslow AR, Domenici E, Essioux L, Kam-Thong T, Airey DC, Calley JN, Collier DA, Wang H, Eastwood B, Ebert P, ... ... Manji H, et al. BrainSeq: Neurogenomics to Drive Novel Target Discovery for Neuropsychiatric Disorders Neuron. 88: 1078-1083. DOI: 10.1016/J.Neuron.2015.10.047 |
0.42 |
|
| 2014 |
de Sousa RT, Machado-Vieira R, Zarate CA, Manji HK. Targeting mitochondrially mediated plasticity to develop improved therapeutics for bipolar disorder. Expert Opinion On Therapeutic Targets. 18: 1131-47. PMID 25056514 DOI: 10.1517/14728222.2014.940893 |
0.42 |
|
| 2012 |
Kaddurah-Daouk R, Yuan P, Boyle SH, Matson W, Wang Z, Zeng ZB, Zhu H, Dougherty GG, Yao JK, Chen G, Guitart X, Carlson PJ, Neumeister A, Zarate C, Krishnan RR, ... Manji HK, et al. Cerebrospinal fluid metabolome in mood disorders-remission state has a unique metabolic profile. Scientific Reports. 2: 667. PMID 22993692 DOI: 10.1038/Srep00667 |
0.374 |
|
| 2012 |
Manji HK, Hsiao JK, Risby ED, Osman OT, Rudorfer MV, Potter WZ. ECT treatment does not enhance neuroendocrine responses to serotonergic challenge. Journal of Psychopharmacology (Oxford, England). 6: 501-8. PMID 22291398 DOI: 10.1177/026988119200600405 |
0.304 |
|
| 2012 |
Koss WA, Einat H, Schloesser RJ, Manji HK, Rubinow DR. Estrogen effects on the forced swim test differ in two outbred rat strains. Physiology & Behavior. 106: 81-6. PMID 22266677 DOI: 10.1016/J.Physbeh.2012.01.004 |
0.3 |
|
| 2012 |
de Bartolomeis A, Tomasetti C, Cicale M, Yuan PX, Manji HK. Chronic treatment with lithium or valproate modulates the expression of Homer1b/c and its related genes Shank and Inositol 1,4,5-trisphosphate receptor. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 22: 527-35. PMID 22245542 DOI: 10.1016/J.Euroneuro.2011.11.006 |
0.362 |
|
| 2012 |
Schloesser RJ, Martinowich K, Manji HK. Mood-stabilizing drugs: mechanisms of action. Trends in Neurosciences. 35: 36-46. PMID 22217451 DOI: 10.1016/j.tins.2011.11.009 |
0.309 |
|
| 2012 |
Quiroz JA, Manji HK. Enhancing synaptic plasticity and cellular resilience to develop novel, improved treatments for mood disorders. Dialogues in Clinical Neuroscience. 4: 73-92. PMID 22034240 |
0.409 |
|
| 2012 |
Charney DS, Dejesus G, Manji HK. Cellular plasticity and resilience and the pathophysiology of severe mood disorders. Dialogues in Clinical Neuroscience. 6: 217-25. PMID 22033657 |
0.394 |
|
| 2012 |
Malkesman O, Austin DR, Tragon T, Wang G, Rompala G, Hamidi AB, Cui Z, Young WS, Nakazawa K, Zarate CA, Manji HK, Chen G. Acute D-serine treatment produces antidepressant-like effects in rodents. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1135-48. PMID 21906419 DOI: 10.1017/S1461145711001386 |
0.36 |
|
| 2011 |
Machado-Vieira R, Manji HK, Zarate CA. Potential novel therapeutics for bipolar disorders. Current Topics in Behavioral Neurosciences. 5: 303-29. PMID 25236562 DOI: 10.1007/7854_2010_51 |
0.37 |
|
| 2011 |
Nanavati D, Austin DR, Catapano LA, Luckenbaugh DA, Dosemeci A, Manji HK, Chen G, Markey SP. The effects of chronic treatment with mood stabilizers on the rat hippocampal post-synaptic density proteome. Journal of Neurochemistry. 119: 617-29. PMID 21838781 DOI: 10.1111/J.1471-4159.2011.07424.X |
0.418 |
|
| 2011 |
Malkesman O, Austin DR, Tragon T, Henter ID, Reed JC, Pellecchia M, Chen G, Manji HK. Targeting the BH3-interacting domain death agonist to develop mechanistically unique antidepressants. Molecular Psychiatry. 17: 770-80. PMID 21727899 DOI: 10.1038/Mp.2011.77 |
0.377 |
|
| 2011 |
Creson TK, Austin DR, Shaltiel G, Mccammon J, Wess J, Manji HK, Chen G. Lithium treatment attenuates muscarinic M1 receptor dysfunction Bipolar Disorders. 13: 238-249. PMID 21676127 DOI: 10.1111/J.1399-5618.2011.00915.X |
0.326 |
|
| 2011 |
Mah L, Zarate CA, Nugent AC, Singh JB, Manji HK, Drevets WC. Neural mechanisms of antidepressant efficacy of the dopamine receptor agonist pramipexole in treatment of bipolar depression International Journal of Neuropsychopharmacology. 14: 545-551. PMID 21029512 DOI: 10.1017/S1461145710001203 |
0.387 |
|
| 2011 |
Machado-Vieira R, Manji HK, Zarate CA. Potential novel therapeutics for bipolar disorders Current Topics in Behavioral Neurosciences. 5: 303-329. DOI: 10.1007/7854_2010_51 |
0.316 |
|
| 2010 |
Diazgranados N, Ibrahim L, Brutsche NE, Newberg A, Kronstein P, Khalife S, Kammerer WA, Quezado Z, Luckenbaugh DA, Salvadore G, Machado-Vieira R, Manji HK, Zarate CA. A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression Archives of General Psychiatry. 67: 793-802. PMID 20679587 DOI: 10.1001/Archgenpsychiatry.2010.90 |
0.355 |
|
| 2010 |
Du J, Wei Y, Liu L, Wang Y, Khairova R, Blumenthal R, Tragon T, Hunsberger JG, Machado-Vieira R, Drevets W, Wang YT, Manji HK. A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. Proceedings of the National Academy of Sciences of the United States of America. 107: 11573-8. PMID 20534517 DOI: 10.1073/Pnas.0913138107 |
0.451 |
|
| 2010 |
Salvadore G, Quiroz JA, Machado-Vieira R, Henter ID, Manji HK, Zarate CA. The neurobiology of the switch process in bipolar disorder: A review Journal of Clinical Psychiatry. 71: 1488-1501. PMID 20492846 DOI: 10.4088/Jcp.09R05259Gre |
0.407 |
|
| 2010 |
Quiroz JA, MacHado-Vieira R, Zarate CA, Manji HK. Novel insights into lithium's mechanism of action: Neurotrophic and neuroprotective effects Neuropsychobiology. 62: 50-60. PMID 20453535 DOI: 10.1159/000314310 |
0.435 |
|
| 2010 |
Cornwell BR, Salvadore G, Colon-Rosario V, Latov DR, Holroyd T, Carver FW, Coppola R, Manji HK, Zarate CA, Grillon C. Abnormal hippocampal functioning and impaired spatial navigation in depressed individuals: evidence from whole-head magnetoencephalography. The American Journal of Psychiatry. 167: 836-44. PMID 20439387 DOI: 10.1176/Appi.Ajp.2009.09050614 |
0.356 |
|
| 2010 |
Schloesser RJ, Lehmann M, Martinowich K, Manji HK, Herkenham M. Environmental enrichment requires adult neurogenesis to facilitate the recovery from psychosocial stress. Molecular Psychiatry. 15: 1152-63. PMID 20308988 DOI: 10.1038/Mp.2010.34 |
0.302 |
|
| 2010 |
Chen G, Henter ID, Manji HK. Translational research in bipolar disorder: emerging insights from genetically based models. Molecular Psychiatry. 15: 883-95. PMID 20142820 DOI: 10.1038/Mp.2010.3 |
0.418 |
|
| 2010 |
Laje G, Cannon DM, Allen AS, Klaver JM, Peck SA, Liu X, Manji HK, Drevets WC, McMahon FJ. Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [11C]DASB. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 715-24. PMID 20047709 DOI: 10.1017/S1461145709991027 |
0.323 |
|
| 2010 |
Yuan P, Zhou R, Wang Y, Li X, Li J, Chen G, Guitart X, Manji HK. Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia. Journal of Affective Disorders. 124: 164-9. PMID 19913919 DOI: 10.1016/J.Jad.2009.10.017 |
0.49 |
|
| 2010 |
Schloesser RJ, Lan M, Manji HK. Neurodegeneration in Psychiatric Illness Encyclopedia of Neuroscience. 279-283. DOI: 10.1016/B978-008045046-9.00513-1 |
0.334 |
|
| 2010 |
Machado-Vieira R, Manji HK, Zarate CA. Novel Therapeutic Strategies for Bipolar Disorder Bipolar Disorder: Clinical and Neurobiological Foundations. 395-411. DOI: 10.1002/9780470661277.ch30 |
0.314 |
|
| 2009 |
Zhou R, Holmes A, Du J, Malkesman O, Yuan P, Wang Y, Damschroder-Williams P, Chen G, Guitart X, Manji HK. Genome-wide gene expression profiling in GluR1 knockout mice: Key role of the calcium signaling pathway in glutamatergically mediated hippocampal transmission European Journal of Neuroscience. 30: 2318-2326. PMID 20092574 DOI: 10.1111/J.1460-9568.2009.07022.X |
0.3 |
|
| 2009 |
Chen G, Henter ID, Manji HK. A role for PKC in mediating stress-induced prefrontal cortical structural plasticity and cognitive function. Proceedings of the National Academy of Sciences of the United States of America. 106: 17613-4. PMID 19828441 DOI: 10.1073/Pnas.0909771106 |
0.356 |
|
| 2009 |
Machado-Vieira R, Yuan P, Brutsche N, DiazGranados N, Luckenbaugh D, Manji HK, Zarate CA. Brain-derived neurotrophic factor and initial antidepressant response to an N-methyl-D-aspartate antagonist Journal of Clinical Psychiatry. 70: 1662-1666. PMID 19744406 DOI: 10.4088/Jcp.08M04659 |
0.365 |
|
| 2009 |
Laje G, Allen AS, Akula N, Manji H, John Rush A, McMahon FJ. Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients. Pharmacogenetics and Genomics. 19: 666-74. PMID 19724244 DOI: 10.1097/Fpc.0B013E32832E4Bcd |
0.311 |
|
| 2009 |
Hunsberger JG, Austin DR, Chen G, Manji HK. Cellular mechanisms underlying affective resiliency: the role of glucocorticoid receptor- and mitochondrially-mediated plasticity. Brain Research. 1293: 76-84. PMID 19595676 DOI: 10.1016/J.Brainres.2009.06.103 |
0.448 |
|
| 2009 |
Zarate CA, Manji HK. Protein kinase C inhibitors: Rationale for use and potential in the treatment of bipolar disorder Cns Drugs. 23: 569-582. PMID 19552485 DOI: 10.2165/00023210-200923070-00003 |
0.503 |
|
| 2009 |
Hunsberger JG, Austin DR, Chen G, Manji HK. MicroRNAs in mental health: from biological underpinnings to potential therapies. Neuromolecular Medicine. 11: 173-82. PMID 19544012 DOI: 10.1007/S12017-009-8070-5 |
0.377 |
|
| 2009 |
Machado-Vieira R, Manji HK, Zarate CA. The role of lithium in the treatment of bipolar disorder: Convergent evidence for neurotrophic effects as a unifying hypothesis Bipolar Disorders. 11: 92-109. PMID 19538689 DOI: 10.1111/J.1399-5618.2009.00714.X |
0.382 |
|
| 2009 |
Creson TK, Hao Y, Engel S, Shen Y, Hamidi A, Zhuo M, Manji HK, Chen G. The anterior cingulate ERK pathway contributes to regulation of behavioral excitement and hedonic activity. Bipolar Disorders. 11: 339-50. PMID 19500087 DOI: 10.1111/J.1399-5618.2009.00697.X |
0.374 |
|
| 2009 |
MacHado-Vieira R, Manji HK, Zarate CA. The role of the tripartite glutamatergic synapse in the pathophysiology and therapeutics of mood disorders Neuroscientist. 15: 525-539. PMID 19471044 DOI: 10.1177/1073858409336093 |
0.303 |
|
| 2009 |
Yuan P, Salvadore G, Li X, Zhang L, Du J, Chen G, Manji HK. Valproate activates the Notch3/c-FLIP signaling cascade: a strategy to attenuate white matter hyperintensities in bipolar disorder in late life? Bipolar Disorders. 11: 256-69. PMID 19419383 DOI: 10.1111/J.1399-5618.2009.00675.X |
0.432 |
|
| 2009 |
Malkesman O, Austin DR, Chen G, Manji HK. Reverse translational strategies for developing animal models of bipolar disorder. Disease Models & Mechanisms. 2: 238-45. PMID 19407332 DOI: 10.1242/Dmm.001628 |
0.416 |
|
| 2009 |
Moore GJ, Cortese BM, Glitz DA, Zajac-Benitez C, Quiroz JA, Uhde TW, Drevets WC, Manji HK. A longitudinal study of the effects of lithium treatment on prefrontal and subgenual prefrontal gray matter volume in treatment-responsive bipolar disorder patients. The Journal of Clinical Psychiatry. 70: 699-705. PMID 19389332 DOI: 10.4088/Jcp.07M03745 |
0.449 |
|
| 2009 |
Martinowich K, Schloesser RJ, Manji HK. Bipolar disorder: from genes to behavior pathways. The Journal of Clinical Investigation. 119: 726-36. PMID 19339764 DOI: 10.1172/Jci37703 |
0.435 |
|
| 2009 |
Malkesman O, Pine DS, Tragon T, Austin DR, Henter ID, Chen G, Manji HK. Animal models of suicide-trait-related behaviors. Trends in Pharmacological Sciences. 30: 165-73. PMID 19269045 DOI: 10.1016/J.Tips.2009.01.004 |
0.314 |
|
| 2009 |
Khairova RA, Machado-Vieira R, Du J, Manji HK. A potential role for pro-inflammatory cytokines in regulating synaptic plasticity in major depressive disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 561-78. PMID 19224657 DOI: 10.1017/S1461145709009924 |
0.388 |
|
| 2009 |
Du J, Wang Y, Hunter R, Wei Y, Blumenthal R, Falke C, Khairova R, Zhou R, Yuan P, Machado-Vieira R, McEwen BS, Manji HK. Dynamic regulation of mitochondrial function by glucocorticoids. Proceedings of the National Academy of Sciences of the United States of America. 106: 3543-8. PMID 19202080 DOI: 10.1073/Pnas.0812671106 |
0.312 |
|
| 2009 |
Salvadore G, Cornwell BR, Colon-Rosario V, Coppola R, Grillon C, Zarate CA, Manji HK. Increased anterior cingulate cortical activity in response to fearful faces: a neurophysiological biomarker that predicts rapid antidepressant response to ketamine. Biological Psychiatry. 65: 289-95. PMID 18822408 DOI: 10.1016/J.Biopsych.2008.08.014 |
0.354 |
|
| 2009 |
Szabo ST, Machado-Vieira R, Yuan P, Wang Y, Wei Y, Falke C, Cirelli C, Tononi G, Manji HK, Du J. Glutamate receptors as targets of protein kinase C in the pathophysiology and treatment of animal models of mania. Neuropharmacology. 56: 47-55. PMID 18789340 DOI: 10.1016/J.Neuropharm.2008.08.015 |
0.416 |
|
| 2009 |
Creson TK, Yuan P, Manji HK, Chen G. Evidence for involvement of ERK, PI3K, and RSK in induction of Bcl-2 by valproate. Journal of Molecular Neuroscience : Mn. 37: 123-34. PMID 18677583 DOI: 10.1007/S12031-008-9122-2 |
0.358 |
|
| 2009 |
Lan MJ, McLoughlin GA, Griffin JL, Tsang TM, Huang JT, Yuan P, Manji H, Holmes E, Bahn S. Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder. Molecular Psychiatry. 14: 269-79. PMID 18256615 DOI: 10.1038/Sj.Mp.4002130 |
0.402 |
|
| 2009 |
Engel SR, Creson TK, Hao Y, Shen Y, Maeng S, Nekrasova T, Landreth GE, Manji HK, Chen G. The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement Molecular Psychiatry. 14: 448-461. PMID 18227838 DOI: 10.1038/Sj.Mp.4002135 |
0.413 |
|
| 2008 |
Salvadore G, Drevets WC, Henter ID, Zarate CA, Manji HK. Early intervention in bipolar disorder, part II: therapeutics. Early Intervention in Psychiatry. 2: 136-46. PMID 19649153 DOI: 10.1111/J.1751-7893.2008.00072.X |
0.394 |
|
| 2008 |
Salvadore G, Drevets WC, Henter ID, Zarate CA, Manji HK. Early intervention in bipolar disorder, part I: clinical and imaging findings. Early Intervention in Psychiatry. 2: 122-35. PMID 19649152 DOI: 10.1111/J.1751-7893.2008.00071.X |
0.384 |
|
| 2008 |
Mallinger AG, Thase ME, Haskett R, Buttenfield J, Luckenbaugh DA, Frank E, Kupfer DJ, Manji HK. Verapamil augmentation of lithium treatment improves outcome in mania unresponsive to lithium alone: preliminary findings and a discussion of therapeutic mechanisms. Bipolar Disorders. 10: 856-66. PMID 19594501 DOI: 10.1111/J.1399-5618.2008.00636.X |
0.374 |
|
| 2008 |
Gelenberg AJ, Thase ME, Meyer RE, Goodwin FK, Katz MM, Kraemer HC, Potter WZ, Shelton RC, Fava M, Khan A, Trivedi MH, Ninan PT, Mann JJ, Bergeson S, Endicott J, ... ... Manji HK, et al. The history and current state of antidepressant clinical trial design: a call to action for proof-of-concept studies. The Journal of Clinical Psychiatry. 69: 1513-28. PMID 19192434 DOI: 10.4088/Jcp.V69N1001 |
0.334 |
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| 2008 |
Holmes MK, Erickson K, Luckenbaugh DA, Drevets WC, Bain EE, Cannon DM, Snow J, Sahakian BJ, Manji HK, Zarate CA. A comparison of cognitive functioning in medicated and unmedicated subjects with bipolar depression. Bipolar Disorders. 10: 806-15. PMID 19032712 DOI: 10.1111/J.1399-5618.2008.00628.X |
0.343 |
|
| 2008 |
Zarate CA, Manji HK. Riluzole in psychiatry: a systematic review of the literature. Expert Opinion On Drug Metabolism & Toxicology. 4: 1223-34. PMID 18721116 DOI: 10.1517/17425255.4.9.1223 |
0.423 |
|
| 2008 |
Zarate CA, Manji HK. Bipolar disorder: candidate drug targets. The Mount Sinai Journal of Medicine, New York. 75: 226-47. PMID 18704977 DOI: 10.1002/Msj.20042 |
0.462 |
|
| 2008 |
Maeng S, Hunsberger JG, Pearson B, Yuan P, Wang Y, Wei Y, McCammon J, Schloesser RJ, Zhou R, Du J, Chen G, McEwen B, Reed JC, Manji HK. BAG1 plays a critical role in regulating recovery from both manic-like and depression-like behavioral impairments. Proceedings of the National Academy of Sciences of the United States of America. 105: 8766-71. PMID 18562287 DOI: 10.1073/Pnas.0803736105 |
0.35 |
|
| 2008 |
Lan MJ, Yuan P, Chen G, Manji HK. Neuronal peroxisome proliferator-activated receptor gamma signaling: regulation by mood-stabilizer valproate. Journal of Molecular Neuroscience : Mn. 35: 225-34. PMID 18437585 DOI: 10.1007/S12031-008-9056-8 |
0.407 |
|
| 2008 |
Machado-Vieira R, Salvadore G, Luckenbaugh DA, Manji HK, Zarate CA. Rapid onset of antidepressant action: a new paradigm in the research and treatment of major depressive disorder. The Journal of Clinical Psychiatry. 69: 946-58. PMID 18435563 DOI: 10.4088/Jcp.V69N0610 |
0.37 |
|
| 2008 |
Sanacora G, Zarate CA, Krystal JH, Manji HK. Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nature Reviews. Drug Discovery. 7: 426-37. PMID 18425072 DOI: 10.1038/Nrd2462 |
0.457 |
|
| 2008 |
Catapano LA, Manji HK. Kinases as drug targets in the treatment of bipolar disorder. Drug Discovery Today. 13: 295-302. PMID 18405841 DOI: 10.1016/J.Drudis.2008.02.007 |
0.477 |
|
| 2008 |
Shaltiel G, Maeng S, Malkesman O, Pearson B, Schloesser RJ, Tragon T, Rogawski M, Gasior M, Luckenbaugh D, Chen G, Manji HK. Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. Molecular Psychiatry. 13: 858-72. PMID 18332879 DOI: 10.1038/Mp.2008.20 |
0.332 |
|
| 2008 |
Gould TD, O'Donnell KC, Picchini AM, Dow ER, Chen G, Manji HK. Generation and behavioral characterization of beta-catenin forebrain-specific conditional knock-out mice. Behavioural Brain Research. 189: 117-25. PMID 18299155 DOI: 10.1016/J.Bbr.2007.12.028 |
0.606 |
|
| 2008 |
Marx CE, Yuan P, Kilts JD, Madison RD, Shampine LJ, Manji HK. Neuroactive steroids, mood stabilizers, and neuroplasticity: alterations following lithium and changes in Bcl-2 knockout mice. The International Journal of Neuropsychopharmacology. 11: 547-52. PMID 18257969 DOI: 10.1017/S1461145708008444 |
0.348 |
|
| 2008 |
Lekman M, Laje G, Charney D, Rush AJ, Wilson AF, Sorant AJ, Lipsky R, Wisniewski SR, Manji H, McMahon FJ, Paddock S. The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort. Biological Psychiatry. 63: 1103-10. PMID 18191112 DOI: 10.1016/J.Biopsych.2007.10.026 |
0.336 |
|
| 2008 |
Mathew SJ, Manji HK, Charney DS. Novel drugs and therapeutic targets for severe mood disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2080-92. PMID 18172433 DOI: 10.1038/Sj.Npp.1301652 |
0.454 |
|
| 2008 |
Du J, Creson TK, Wu LJ, Ren M, Gray NA, Falke C, Wei Y, Wang Y, Blumenthal R, Machado-Vieira R, Yuan P, Chen G, Zhuo M, Manji HK. The role of hippocampal GluR1 and GluR2 receptors in manic-like behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 68-79. PMID 18171924 DOI: 10.1523/Jneurosci.3080-07.2008 |
0.385 |
|
| 2008 |
Gould TD, O'Donnell KC, Dow ER, Du J, Chen G, Manji HK. Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test. Neuropharmacology. 54: 577-87. PMID 18096191 DOI: 10.1016/J.Neuropharm.2007.11.002 |
0.63 |
|
| 2008 |
Newberg AR, Catapano LA, Zarate CA, Manji HK. Neurobiology of bipolar disorder. Expert Review of Neurotherapeutics. 8: 93-110. PMID 18088203 DOI: 10.1586/14737175.8.1.93 |
0.47 |
|
| 2008 |
Schloesser RJ, Huang J, Klein PS, Manji HK. Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 110-33. PMID 17912251 DOI: 10.1038/Sj.Npp.1301575 |
0.46 |
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| 2008 |
Maeng S, Zarate CA, Du J, Schloesser RJ, McCammon J, Chen G, Manji HK. Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors. Biological Psychiatry. 63: 349-52. PMID 17643398 DOI: 10.1016/J.Biopsych.2007.05.028 |
0.35 |
|
| 2008 |
Arnsten A, Manji H. Mania: a rational neurobiology Future Neurology. 3: 125-131. DOI: 10.2217/14796708.3.2.125 |
0.414 |
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| 2008 |
Mathew SJ, Manji HK, Charney DS. Novel drugs and therapeutic targets for severe mood disorders (Neuropsychopharmacology (2008) DOI: 10.1038/sj.npp.1301652) Neuropsychopharmacology. 33: 2300. DOI: 10.1038/Npp.2008.84 |
0.327 |
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| 2008 |
Gould T, Kovacsics C, O'Donnell K, Dow E, Chen G, Manji H. S.20.04 Lithium responsive behavioural models: a tool for understanding atypical antipsychotic action in bipolar depression and mania European Neuropsychopharmacology. 18. DOI: 10.1016/S0924-977X(08)70191-3 |
0.614 |
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| 2007 |
Angst J, Gamma A, Gerber-Werder R, Zarate CA, Manji HK. Does long-term medication with lithium, clozapine or antidepressants prevent or attenuate dementia in bipolar and depressed patients? International Journal of Psychiatry in Clinical Practice. 11: 2-8. PMID 24941269 DOI: 10.1080/13651500600810133 |
0.37 |
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| 2007 |
Laje G, Paddock S, Manji H, Rush AJ, Wilson AF, Charney D, McMahon FJ. Genetic markers of suicidal ideation emerging during citalopram treatment of major depression. The American Journal of Psychiatry. 164: 1530-8. PMID 17898344 DOI: 10.1176/Appi.Ajp.2007.06122018 |
0.302 |
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| 2007 |
Zarate CA, Singh JB, Carlson PJ, Quiroz J, Jolkovsky L, Luckenbaugh DA, Manji HK. Efficacy of a protein kinase C inhibitor (tamoxifen) in the treatment of acute mania: a pilot study. Bipolar Disorders. 9: 561-70. PMID 17845270 DOI: 10.1111/J.1399-5618.2007.00530.X |
0.34 |
|
| 2007 |
Martinowich K, Manji H, Lu B. New insights into BDNF function in depression and anxiety. Nature Neuroscience. 10: 1089-93. PMID 17726474 DOI: 10.1038/Nn1971 |
0.424 |
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| 2007 |
Cannon DM, Ichise M, Rollis D, Klaver JM, Gandhi SK, Charney DS, Manji HK, Drevets WC. Elevated serotonin transporter binding in major depressive disorder assessed using positron emission tomography and [11C]DASB; comparison with bipolar disorder. Biological Psychiatry. 62: 870-7. PMID 17678634 DOI: 10.1016/J.Biopsych.2007.03.016 |
0.389 |
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| 2007 |
Einat H, Yuan P, Szabo ST, Dogra S, Manji HK. Protein kinase C inhibition by tamoxifen antagonizes manic-like behavior in rats: implications for the development of novel therapeutics for bipolar disorder. Neuropsychobiology. 55: 123-31. PMID 17641532 DOI: 10.1159/000106054 |
0.448 |
|
| 2007 |
Hu XZ, Rush AJ, Charney D, Wilson AF, Sorant AJ, Papanicolaou GJ, Fava M, Trivedi MH, Wisniewski SR, Laje G, Paddock S, McMahon FJ, Manji H, Lipsky RH. Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression. Archives of General Psychiatry. 64: 783-92. PMID 17606812 DOI: 10.1001/Archpsyc.64.7.783 |
0.312 |
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| 2007 |
Chuang DM, Manji HK. In search of the Holy Grail for the treatment of neurodegenerative disorders: has a simple cation been overlooked? Biological Psychiatry. 62: 4-6. PMID 17572175 DOI: 10.1016/J.Biopsych.2007.04.008 |
0.42 |
|
| 2007 |
Gould TD, Dow ER, O'Donnell KC, Chen G, Manji HK. Targeting signal transduction pathways in the treatment of mood disorders: recent insights into the relevance of the Wnt pathway. Cns & Neurological Disorders Drug Targets. 6: 193-204. PMID 17511616 DOI: 10.2174/187152707780619308 |
0.69 |
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| 2007 |
Agid Y, Buzsáki G, Diamond DM, Frackowiak R, Giedd J, Girault JA, Grace A, Lambert JJ, Manji H, Mayberg H, Popoli M, Prochiantz A, Richter-Levin G, Somogyi P, Spedding M, et al. How can drug discovery for psychiatric disorders be improved? Nature Reviews. Drug Discovery. 6: 189-201. PMID 17330070 DOI: 10.1038/Nrd2217 |
0.448 |
|
| 2007 |
Gould NF, Holmes MK, Fantie BD, Luckenbaugh DA, Pine DS, Gould TD, Burgess N, Manji HK, Zarate CA. Performance on a virtual reality spatial memory navigation task in depressed patients. The American Journal of Psychiatry. 164: 516-9. PMID 17329478 DOI: 10.1176/Ajp.2007.164.3.516 |
0.577 |
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| 2007 |
Gould TD, Einat H, O'Donnell KC, Picchini AM, Schloesser RJ, Manji HK. Beta-catenin overexpression in the mouse brain phenocopies lithium-sensitive behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2173-83. PMID 17299510 DOI: 10.1038/Sj.Npp.1301338 |
0.598 |
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| 2007 |
Schloesser RJ, Chen G, Manji HK. Neurogenesis and neuroenhancement in the pathophysiology and treatment of bipolar disorder. International Review of Neurobiology. 77: 143-78. PMID 17178474 DOI: 10.1016/S0074-7742(06)77005-2 |
0.435 |
|
| 2007 |
Kling MA, Alesci S, Csako G, Costello R, Luckenbaugh DA, Bonne O, Duncko R, Drevets WC, Manji HK, Charney DS, Gold PW, Neumeister A. Sustained low-grade pro-inflammatory state in unmedicated, remitted women with major depressive disorder as evidenced by elevated serum levels of the acute phase proteins C-reactive protein and serum amyloid A. Biological Psychiatry. 62: 309-13. PMID 17178112 DOI: 10.1016/J.Biopsych.2006.09.033 |
0.334 |
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| 2007 |
Gould TD, O'Donnell KC, Picchini AM, Manji HK. Strain differences in lithium attenuation of d-amphetamine-induced hyperlocomotion: a mouse model for the genetics of clinical response to lithium. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1321-33. PMID 17151598 DOI: 10.1038/Sj.Npp.1301254 |
0.568 |
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| 2007 |
Catapano LA, Manji HK. G protein-coupled receptors in major psychiatric disorders. Biochimica Et Biophysica Acta. 1768: 976-93. PMID 17078926 DOI: 10.1016/J.Bbamem.2006.09.025 |
0.454 |
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| 2007 |
Alesci S, Rodak M, Ilias I, Zhou R, Manji HK. The genomics of mood disorders. Progress in Brain Research. 158: 129-39. PMID 17027694 DOI: 10.1016/S0079-6123(06)58006-9 |
0.49 |
|
| 2007 |
Du J, Suzuki K, Wei Y, Wang Y, Blumenthal R, Chen Z, Falke C, Zarate CA, Manji HK. The anticonvulsants lamotrigine, riluzole, and valproate differentially regulate AMPA receptor membrane localization: relationship to clinical effects in mood disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 793-802. PMID 16936714 DOI: 10.1038/Sj.Npp.1301178 |
0.414 |
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| 2006 |
Machado-Vieira R, Zarate CA, Manji HK. Emerging Novel Treatments for Severe Mood Disorders Involving Cellular Plasticity Cascades. Current Psychosis & Therapeutics Reports. 4: 181-190. PMID 25620894 DOI: 10.1007/Bf02629394 |
0.515 |
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| 2006 |
Du J, Machado-Vieira R, Maeng S, Martinowich K, Manji HK, Zarate CA. Enhancing AMPA to NMDA throughput as a convergent mechanism for antidepressant action. Drug Discovery Today. Therapeutic Strategies. 3: 519-526. PMID 25411578 DOI: 10.1016/J.Ddstr.2006.11.012 |
0.312 |
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| 2006 |
Gould TD, Picchini AM, Einat H, Manji HK. Targeting glycogen synthase kinase-3 in the CNS: implications for the development of new treatments for mood disorders. Current Drug Targets. 7: 1399-409. PMID 17100580 DOI: 10.2174/1389450110607011399 |
0.702 |
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| 2006 |
Shaltiel G, Chen G, Manji HK. Neurotrophic signaling cascades in the pathophysiology and treatment of bipolar disorder. Current Opinion in Pharmacology. 7: 22-6. PMID 17055337 DOI: 10.1016/J.Coph.2006.07.005 |
0.473 |
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| 2006 |
Mah L, Zarate CA, Singh J, Duan YF, Luckenbaugh DA, Manji HK, Drevets WC. Regional cerebral glucose metabolic abnormalities in bipolar II depression. Biological Psychiatry. 61: 765-75. PMID 17027930 DOI: 10.1016/J.Biopsych.2006.06.009 |
0.408 |
|
| 2006 |
Zarate CA, Singh JB, Carlson PJ, Brutsche NE, Ameli R, Luckenbaugh DA, Charney DS, Manji HK. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Archives of General Psychiatry. 63: 856-64. PMID 16894061 DOI: 10.1001/Archpsyc.63.8.856 |
0.403 |
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| 2006 |
Cannon DM, Ichise M, Fromm SJ, Nugent AC, Rollis D, Gandhi SK, Klaver JM, Charney DS, Manji HK, Drevets WC. Serotonin transporter binding in bipolar disorder assessed using [11C]DASB and positron emission tomography. Biological Psychiatry. 60: 207-17. PMID 16875929 DOI: 10.1016/J.Biopsych.2006.05.005 |
0.351 |
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| 2006 |
McMahon FJ, Buervenich S, Charney D, Lipsky R, Rush AJ, Wilson AF, Sorant AJ, Papanicolaou GJ, Laje G, Fava M, Trivedi MH, Wisniewski SR, Manji H. Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment. American Journal of Human Genetics. 78: 804-14. PMID 16642436 DOI: 10.1086/503820 |
0.363 |
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| 2006 |
Chen G, Manji HK. The extracellular signal-regulated kinase pathway: an emerging promising target for mood stabilizers. Current Opinion in Psychiatry. 19: 313-23. PMID 16612219 DOI: 10.1097/01.yco.0000218604.63463.cd |
0.368 |
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| 2006 |
Carlson PJ, Singh JB, Zarate CA, Drevets WC, Manji HK. Neural circuitry and neuroplasticity in mood disorders: insights for novel therapeutic targets. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 22-41. PMID 16490411 DOI: 10.1016/J.Nurx.2005.12.009 |
0.477 |
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| 2006 |
Zarate CA, Singh J, Manji HK. Cellular plasticity cascades: targets for the development of novel therapeutics for bipolar disorder. Biological Psychiatry. 59: 1006-20. PMID 16487491 DOI: 10.1016/J.Biopsych.2005.10.021 |
0.487 |
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| 2006 |
Einat H, Manji HK. Cellular plasticity cascades: genes-to-behavior pathways in animal models of bipolar disorder. Biological Psychiatry. 59: 1160-71. PMID 16457783 DOI: 10.1016/J.Biopsych.2005.11.004 |
0.455 |
|
| 2006 |
Hasler G, Drevets WC, Gould TD, Gottesman II, Manji HK. Toward constructing an endophenotype strategy for bipolar disorders. Biological Psychiatry. 60: 93-105. PMID 16406007 DOI: 10.1016/J.Biopsych.2005.11.006 |
0.723 |
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| 2006 |
Zarate CA, Singh JB, Quiroz JA, De Jesus G, Denicoff KK, Luckenbaugh DA, Manji HK, Charney DS. A double-blind, placebo-controlled study of memantine in the treatment of major depression. The American Journal of Psychiatry. 163: 153-5. PMID 16390905 DOI: 10.1176/Appi.Ajp.163.1.153 |
0.311 |
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| 2006 |
Cannon DM, Ichise M, Fromm S, Nugent AC, Rollis D, Gandhi SK, Klaver JM, Charney DS, Manji HK, Drevets WC. Serotonin transporter binding in major depressive disorder and bipolar disorder assessed using [11C]DASB and positron emission tomography Neuroimage. 31. DOI: 10.1016/J.Neuroimage.2006.04.032 |
0.396 |
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| 2005 |
Bachmann RF, Schloesser RJ, Gould TD, Manji HK. Mood stabilizers target cellular plasticity and resilience cascades: implications for the development of novel therapeutics. Molecular Neurobiology. 32: 173-202. PMID 16215281 DOI: 10.1385/Mn:32:2:173 |
0.696 |
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| 2005 |
Zhou R, Zarate CA, Manji HK. Identification of molecular mechanisms underlying mood stabilization through genome-wide gene expression profiling. The International Journal of Neuropsychopharmacology. 9: 263-6. PMID 16207389 DOI: 10.1017/S1461145705006176 |
0.353 |
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| 2005 |
Einat H, Yuan P, Manji HK. Increased anxiety-like behaviors and mitochondrial dysfunction in mice with targeted mutation of the Bcl-2 gene: further support for the involvement of mitochondrial function in anxiety disorders. Behavioural Brain Research. 165: 172-80. PMID 16095731 DOI: 10.1016/J.Bbr.2005.06.012 |
0.374 |
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| 2005 |
Zhou R, Gray NA, Yuan P, Li X, Chen J, Chen G, Damschroder-Williams P, Du J, Zhang L, Manji HK. The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4493-502. PMID 15872096 DOI: 10.1523/Jneurosci.4530-04.2005 |
0.479 |
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| 2005 |
Neumeister A, Charney DS, Belfer I, Geraci M, Holmes C, Sharabi Y, Alim T, Bonne O, Luckenbaugh DA, Manji H, Goldman D, Goldstein DS. Sympathoneural and adrenomedullary functional effects of alpha2C-adrenoreceptor gene polymorphism in healthy humans. Pharmacogenetics and Genomics. 15: 143-9. PMID 15861038 DOI: 10.1097/01213011-200503000-00002 |
0.316 |
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| 2005 |
Gould TD, Manji HK. Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1223-37. PMID 15827567 DOI: 10.1038/Sj.Npp.1300731 |
0.662 |
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| 2005 |
Neumeister A, Yuan P, Young TA, Bonne O, Luckenbaugh DA, Charney DS, Manji H. Effects of tryptophan depletion on serum levels of brain-derived neurotrophic factor in unmedicated patients with remitted depression and healthy subjects. The American Journal of Psychiatry. 162: 805-7. PMID 15800160 DOI: 10.1176/Appi.Ajp.162.4.805 |
0.398 |
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| 2005 |
Zarate CA, Quiroz JA, Singh JB, Denicoff KD, De Jesus G, Luckenbaugh DA, Charney DS, Manji HK. An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression. Biological Psychiatry. 57: 430-2. PMID 15705360 DOI: 10.1016/J.Biopsych.2004.11.023 |
0.411 |
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| 2005 |
Gould TD, Manji HK. DARPP-32: A molecular switch at the nexus of reward pathway plasticity. Proceedings of the National Academy of Sciences of the United States of America. 102: 253-4. PMID 15632217 DOI: 10.1073/Pnas.0408700102 |
0.587 |
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| 2005 |
Quiroz JA, Singh J, Gould TD, Denicoff KD, Zarate CA, Manji HK. Emerging experimental therapeutics for bipolar disorder: clues from the molecular pathophysiology. Molecular Psychiatry. 9: 756-76. PMID 15136795 DOI: 10.1038/Sj.Mp.4001521 |
0.661 |
|
| 2005 |
Gould TD, Quiroz JA, Singh J, Zarate CA, Manji HK. Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers. Molecular Psychiatry. 9: 734-55. PMID 15136794 DOI: 10.1038/Sj.Mp.4001518 |
0.654 |
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| 2005 |
Manji H. S14 IMPAIRMENTS OF CELLULAR PLASTICITY AND RESILIENCE IN SEVERE MOOD DISORDERS: THERAPEUTIC IMPLICATIONS Behavioural Pharmacology. 16: S5. DOI: 10.1097/00008877-200509001-00014 |
0.307 |
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| 2005 |
Yuan PX, Zhou R, Farzad N, Gould TD, Gray NA, Du J, Manji HK. Chapter 5.7 Enhancing resilience to stress: the role of signaling cascades Techniques in the Behavioral and Neural Sciences. 15: 751-771. DOI: 10.1016/S0921-0709(05)80040-9 |
0.624 |
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| 2005 |
Zarate CA, Singh JB, Carlson PJ, Manji HK. Molecular mechanisms of bipolar disorder Drug Discovery Today: Disease Mechanisms. 2: 435-445. DOI: 10.1016/J.Ddmec.2005.11.005 |
0.465 |
|
| 2004 |
Du J, Quiroz JA, Gray NA, Szabo ST, Zarate CA, Manji HK. Regulation of cellular plasticity and resilience by mood stabilizers: the role of AMPA receptor trafficking. Dialogues in Clinical Neuroscience. 6: 143-55. PMID 22034247 |
0.326 |
|
| 2004 |
Du J, Quiroz J, Yuan P, Zarate C, Manji HK. Bipolar disorder: involvement of signaling cascades and AMPA receptor trafficking at synapses. Neuron Glia Biology. 1: 231-43. PMID 18634600 DOI: 10.1017/S1740925X05000098 |
0.475 |
|
| 2004 |
Einat H, Chen G, Manji H. [Possible involvement of protein kinase C in the pathophysiology and treatment of bipolar disorder]. Harefuah. 143: 420-5, 462. PMID 15524099 |
0.407 |
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| 2004 |
Birnbaum SG, Yuan PX, Wang M, Vijayraghavan S, Bloom AK, Davis DJ, Gobeske KT, Sweatt JD, Manji HK, Arnsten AF. Protein kinase C overactivity impairs prefrontal cortical regulation of working memory. Science (New York, N.Y.). 306: 882-4. PMID 15514161 DOI: 10.1126/Science.1100021 |
0.314 |
|
| 2004 |
Quiroz JA, Gould TD, Manji HK. Molecular effects of lithium. Molecular Interventions. 4: 259-72. PMID 15471909 DOI: 10.1124/Mi.4.5.6 |
0.693 |
|
| 2004 |
Gould TD, Einat H, Bhat R, Manji HK. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. The International Journal of Neuropsychopharmacology. 7: 387-90. PMID 15315719 DOI: 10.1017/S1461145704004535 |
0.642 |
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| 2004 |
Hao Y, Creson T, Zhang L, Li P, Du F, Yuan P, Gould TD, Manji HK, Chen G. Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6590-9. PMID 15269271 DOI: 10.1523/Jneurosci.5747-03.2004 |
0.645 |
|
| 2004 |
Du J, Gray NA, Falke CA, Chen W, Yuan P, Szabo ST, Einat H, Manji HK. Modulation of synaptic plasticity by antimanic agents: the role of AMPA glutamate receptor subunit 1 synaptic expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6578-89. PMID 15269270 DOI: 10.1523/Jneurosci.1258-04.2004 |
0.369 |
|
| 2004 |
Zarate CA, Payne JL, Singh J, Quiroz JA, Luckenbaugh DA, Denicoff KD, Charney DS, Manji HK. Pramipexole for bipolar II depression: a placebo-controlled proof of concept study. Biological Psychiatry. 56: 54-60. PMID 15219473 DOI: 10.1016/J.Biopsych.2004.03.013 |
0.398 |
|
| 2004 |
Hasler G, Drevets WC, Manji HK, Charney DS. Discovering endophenotypes for major depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1765-81. PMID 15213704 DOI: 10.1038/Sj.Npp.1300506 |
0.362 |
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| 2004 |
Ozerdem A, Schmidt ME, Manji HK, Risinger RC, Potter WZ. Chronic lithium administration enhances noradrenergic responses to intravenous administration of the alpha2 antagonist idazoxan in healthy volunteers. Journal of Clinical Psychopharmacology. 24: 150-4. PMID 15206661 DOI: 10.1097/01.Jcp.0000115667.45074.9F |
0.325 |
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| 2004 |
Gould TD, Manji HK. The molecular medicine revolution and psychiatry: bridging the gap between basic neuroscience research and clinical psychiatry. The Journal of Clinical Psychiatry. 65: 598-604. PMID 15163244 DOI: 10.4088/Jcp.V65N0502 |
0.586 |
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| 2004 |
Du J, Szabo ST, Gray NA, Manji HK. Focus on CaMKII: a molecular switch in the pathophysiology and treatment of mood and anxiety disorders. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 7: 243-8. PMID 15154976 DOI: 10.1017/S1461145704004432 |
0.401 |
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| 2004 |
Charney DS, Manji HK. Life stress, genes, and depression: multiple pathways lead to increased risk and new opportunities for intervention Science's Stke : Signal Transduction Knowledge Environment. 2004. PMID 15039492 DOI: 10.1126/Stke.2252004Re5 |
0.403 |
|
| 2004 |
Gould TD, Zarate CA, Manji HK. Glycogen synthase kinase-3: a target for novel bipolar disorder treatments. The Journal of Clinical Psychiatry. 65: 10-21. PMID 14744163 |
0.655 |
|
| 2004 |
Zarate CA, Payne JL, Quiroz J, Sporn J, Denicoff KK, Luckenbaugh D, Charney DS, Manji HK. An open-label trial of riluzole in patients with treatment-resistant major depression. The American Journal of Psychiatry. 161: 171-4. PMID 14702270 DOI: 10.1176/Appi.Ajp.161.1.171 |
0.324 |
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| 2004 |
Einat H, Manji HK, Gould TD, Du J, Chen G. Possible involvement of the ERK signaling cascade in bipolar disorder: behavioral leads from the study of mutant mice. Drug News & Perspectives. 16: 453-63. PMID 14668941 DOI: 10.1358/DNP.2003.16.7.829357 |
0.626 |
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| 2004 |
Gould TD, Chen G, Manji HK. In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 32-8. PMID 12942141 DOI: 10.1038/Sj.Npp.1300283 |
0.635 |
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| 2004 |
Picchini AM, Manji HK, Gould TD. GSK-3 and neurotrophic signaling: novel targets underlying the pathophysiology and treatment of mood disorders? Drug Discovery Today: Disease Mechanisms. 1: 419-428. DOI: 10.1016/J.Ddmec.2004.11.020 |
0.689 |
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| 2004 |
Yuan P, Gould TD, Gray NA, Bachmann RF, Schloesser RJ, Lan MJK, Du J, Moore GJ, Manji HK. Neurotrophic signaling cascades are major long-term targets for lithium: Clinical implications Clinical Neuroscience Research. 4: 137-153. DOI: 10.1016/J.Cnr.2004.09.006 |
0.68 |
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| 2004 |
Gould TD, Zarate CA, Manji HK. Glycogen synthase kinase-3: a target for novel bipolar disorder treatments. The Journal of Clinical Psychiatry. 65: 10-21. DOI: 10.1002/0470052171.Ch7 |
0.686 |
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| 2003 |
Manji HK, Quiroz JA, Payne JL, Singh J, Lopes BP, Viegas JS, Zarate CA. The underlying neurobiology of bipolar disorder. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 2: 136-46. PMID 16946919 |
0.392 |
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| 2003 |
Du J, Gray NA, Falke C, Yuan P, Szabo S, Manji HK. Structurally dissimilar antimanic agents modulate synaptic plasticity by regulating AMPA glutamate receptor subunit GluR1 synaptic expression. Annals of the New York Academy of Sciences. 1003: 378-80. PMID 14684466 DOI: 10.1196/Annals.1300.031 |
0.346 |
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| 2003 |
Zarate CA, Du J, Quiroz J, Gray NA, Denicoff KD, Singh J, Charney DS, Manji HK. Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: role of the glutamatergic system. Annals of the New York Academy of Sciences. 1003: 273-91. PMID 14684452 DOI: 10.1196/Annals.1300.017 |
0.494 |
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| 2003 |
Manji HK, Gottesman II, Gould TD. Signal transduction and genes-to-behaviors pathways in psychiatric diseases. Science's Stke : Signal Transduction Knowledge Environment. 2003: pe49. PMID 14600293 DOI: 10.1126/Stke.2003.207.Pe49 |
0.704 |
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| 2003 |
Ketter TA, Manji HK, Post RM. Potential mechanisms of action of lamotrigine in the treatment of bipolar disorders. Journal of Clinical Psychopharmacology. 23: 484-95. PMID 14520126 DOI: 10.1097/01.jcp.0000088915.02635.e8 |
0.338 |
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| 2003 |
Einat H, Yuan P, Gould TD, Li J, Du J, Zhang L, Manji HK, Chen G. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7311-6. PMID 12917364 DOI: 10.1523/Jneurosci.23-19-07311.2003 |
0.655 |
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| 2003 |
Dick DM, Foroud T, Flury L, Bowman ES, Miller MJ, Rau NL, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Hahn R, Widmark C, et al. Genomewide linkage analyses of bipolar disorder: a new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative. American Journal of Human Genetics. 73: 107-14. PMID 12772088 DOI: 10.1086/376562 |
0.354 |
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| 2003 |
Gould TD, Gray NA, Manji HK. Effects of a glycogen synthase kinase-3 inhibitor, lithium, in adenomatous polyposis coli mutant mice. Pharmacological Research. 48: 49-53. PMID 12770514 DOI: 10.1016/S1043-6618(03)00096-3 |
0.639 |
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| 2003 |
Gray NA, Zhou R, Du J, Moore GJ, Manji HK. The use of mood stabilizers as plasticity enhancers in the treatment of neuropsychiatric disorders. The Journal of Clinical Psychiatry. 64: 3-17. PMID 12720479 |
0.399 |
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| 2003 |
Manji HK, Quiroz JA, Sporn J, Payne JL, Denicoff K, A Gray N, Zarate CA, Charney DS. Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression. Biological Psychiatry. 53: 707-42. PMID 12706957 DOI: 10.1016/S0006-3223(03)00117-3 |
0.495 |
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| 2003 |
Li J, Gould TD, Yuan P, Manji HK, Chen G. Post-mortem interval effects on the phosphorylation of signaling proteins. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1017-25. PMID 12637955 DOI: 10.1038/Sj.Npp.1300112 |
0.617 |
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| 2002 |
Gould TD, Chen G, Manji HK. Mood stabilizer psychopharmacology. Clinical Neuroscience Research. 2: 193-212. PMID 22707923 DOI: 10.1016/S1566-2772(02)00044-0 |
0.666 |
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| 2002 |
Glitz DA, Manji HK, Moore GJ. Mood disorders: treatment-induced changes in brain neurochemistry and structure. Seminars in Clinical Neuropsychiatry. 7: 269-80. PMID 12382209 DOI: 10.1053/Scnp.2002.35226 |
0.437 |
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| 2002 |
Gould TD, Manji HK. The Wnt signaling pathway in bipolar disorder. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 8: 497-511. PMID 12374432 DOI: 10.1177/107385802237176 |
0.677 |
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| 2002 |
Nestler EJ, Gould E, Manji H, Buncan M, Duman RS, Greshenfeld HK, Hen R, Koester S, Lederhendler I, Meaney M, Robbins T, Winsky L, Zalcman S. Preclinical models: status of basic research in depression. Biological Psychiatry. 52: 503-28. PMID 12361666 DOI: 10.1016/S0006-3223(02)01405-1 |
0.481 |
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| 2002 |
Gould TD, Manji HK. Signaling networks in the pathophysiology and treatment of mood disorders. Journal of Psychosomatic Research. 53: 687-97. PMID 12169343 DOI: 10.1016/S0022-3999(02)00426-9 |
0.677 |
|
| 2002 |
Coyle JT, Manji HK. Getting balance: drugs for bipolar disorder share target. Nature Medicine. 8: 557-8. PMID 12042799 DOI: 10.1038/Nm0602-557 |
0.435 |
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| 2002 |
Lenox RH, Gould TD, Manji HK. Endophenotypes in bipolar disorder. American Journal of Medical Genetics. 114: 391-406. PMID 11992561 DOI: 10.1002/Ajmg.10360 |
0.66 |
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| 2002 |
Manji HK, Chen G. PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers. Molecular Psychiatry. S46-56. PMID 11986995 DOI: 10.1038/sj.mp.4001018 |
0.397 |
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| 2002 |
Manji HK, Zarate CA. Molecular and cellular mechanisms underlying mood stabilization in bipolar disorder: implications for the development of improved therapeutics. Molecular Psychiatry. S1-7. PMID 11986989 DOI: 10.1038/Sj.Mp.4001068 |
0.43 |
|
| 2002 |
Manji HK, Chen G. Post-receptor signaling pathways in the pathophysiology and treatment of mood disorders. Current Psychiatry Reports. 2: 479-89. PMID 11122999 DOI: 10.1007/S11920-000-0006-6 |
0.403 |
|
| 2002 |
Manji H, Zhou R, Chen G. Neuroplasticity and cellular resilience in bipolar disorder Bipolar Disorders. 4: 56-57. DOI: 10.1034/J.1399-5618.4.S1.21.X |
0.406 |
|
| 2002 |
Manji HK, Young LT. Structural plasticity and neuronal resilience: are these targets for mood stabilizers and antidepressants in the treatment of bipolar disorder? Bipolar Disorders. 4: 77-79. DOI: 10.1034/J.1399-5618.2002.00001.X |
0.424 |
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| 2001 |
Manji HK, Moore GJ, Chen G. Bipolar disorder: leads from the molecular and cellular mechanisms of action of mood stabilizers. The British Journal of Psychiatry. Supplement. 41: s107-19. PMID 11450170 DOI: 10.1192/Bjp.178.41.S107 |
0.448 |
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| 2001 |
Yuan PX, Huang LD, Jiang YM, Gutkind JS, Manji HK, Chen G. The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. The Journal of Biological Chemistry. 276: 31674-83. PMID 11418608 DOI: 10.1074/Jbc.M104309200 |
0.348 |
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| 2001 |
Chen G, Huang LD, Zeng WZ, Manji HK. Mood stabilizers regulate cytoprotective and mRNA-binding proteins in the brain: long-term effects on cell survival and transcript stability. The International Journal of Neuropsychopharmacology. 4: 47-64. PMID 11343630 DOI: 10.1017/S146114570100222X |
0.405 |
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| 2001 |
Manji HK, Drevets WC, Charney DS. The cellular neurobiology of depression Nature Medicine. 7: 541-547. PMID 11329053 DOI: 10.1038/87865 |
0.411 |
|
| 2001 |
Chen G, Masana MI, Manji HK. Lithium regulates PKC-mediated intracellular cross-talk and gene expression in the CNS in vivo. Bipolar Disorders. 2: 217-36. PMID 11249800 DOI: 10.1034/J.1399-5618.2000.20303.X |
0.453 |
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| 2001 |
Ikonomov OC, Petrov T, Soden K, Shisheva A, Manji HK. Lithium treatment in ovo: effects on embryonic heart rate, natural death of ciliary ganglion neurons, and brain expression of a highly conserved chicken homolog of human MTG8/ETO. Brain Research. Developmental Brain Research. 123: 13-24. PMID 11020546 DOI: 10.1016/S0165-3806(00)00074-2 |
0.332 |
|
| 2001 |
Manji HK, Lenox RH. Signaling: cellular insights into the pathophysiology of bipolar disorder. Biological Psychiatry. 48: 518-30. PMID 11018224 DOI: 10.1016/S0006-3223(00)00929-X |
0.467 |
|
| 2001 |
Manji HK, Moore GJ, Chen G. Bipolar disorder: leads from the molecular and cellular mechanisms of action of mood stabilisers British Journal of Psychiatry. 178: s107-s119. DOI: 10.1192/BJP.178.41.S107 |
0.345 |
|
| 2000 |
Manji HK, Moore GJ, Rajkowska G, Chen G. Neuroplasticity and cellular resilience in mood disorders. Molecular Psychiatry. 5: 578-93. PMID 11126389 DOI: 10.1038/Sj.Mp.4000811 |
0.466 |
|
| 2000 |
Manji HK, Moore GJ, Chen G. Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness. Biological Psychiatry. 48: 740-54. PMID 11063971 DOI: 10.1016/S0006-3223(00)00979-3 |
0.484 |
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| 2000 |
Chen G, Rajkowska G, Du F, Seraji-Bozorgzad N, Manji HK. Enhancement of hippocampal neurogenesis by lithium. Journal of Neurochemistry. 75: 1729-34. PMID 10987856 DOI: 10.1046/J.1471-4159.2000.0751729.X |
0.393 |
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| 2000 |
Soares JC, Chen G, Dippold CS, Wells KF, Frank E, Kupfer DJ, Manji HK, Mallinger AG. Concurrent measures of protein kinase C and phosphoinositides in lithium-treated bipolar patients and healthy individuals: a preliminary study. Psychiatry Research-Neuroimaging. 95: 109-118. PMID 10963797 DOI: 10.1016/S0165-1781(00)00175-X |
0.331 |
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| 2000 |
Moore GJ, Bebchuk JM, Hasanat K, Chen G, Seraji-Bozorgzad N, Wilds IB, Faulk MW, Koch S, Glitz DA, Jolkovsky L, Manji HK. Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects? Biological Psychiatry. 48: 1-8. PMID 10913502 DOI: 10.1016/S0006-3223(00)00252-3 |
0.353 |
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| 2000 |
Bebchuk JM, Arfken CL, Dolan-Manji S, Murphy J, Hasanat K, Manji HK. A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania [2] Archives of General Psychiatry. 57: 95-97. PMID 10632242 DOI: 10.1001/Archpsyc.57.1.95 |
0.313 |
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| 2000 |
Manji HK, McNamara R, Chen G, Lenox RH. Signalling pathways in the brain: cellular transduction of mood stabilisation in the treatment of manic-depressive illness. The Australian and New Zealand Journal of Psychiatry. S65-83. PMID 10622182 DOI: 10.1111/J.1440-1614.1999.00670.X |
0.437 |
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| 1999 |
Moore GJ, Bebchuk JM, Parrish JK, Faulk MW, Arfken CL, Strahl-Bevacqua J, Manji HK. Temporal dissociation between lithium-induced changes in frontal lobe myo-inositol and clinical response in manic-depressive illness. The American Journal of Psychiatry. 156: 1902-8. PMID 10588403 DOI: 10.1176/Ajp.156.12.1902 |
0.42 |
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| 1999 |
Yuan P, Chen G, Manji HK. Lithium activates the c-Jun NH2-terminal kinases in vitro and in the CNS in vivo. Journal of Neurochemistry. 73: 2299-309. PMID 10582587 DOI: 10.1046/J.1471-4159.1999.0732299.X |
0.411 |
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| 1999 |
Manji HK, Lenox RH. Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness. Biological Psychiatry. 46: 1328-51. PMID 10578449 DOI: 10.1016/S0006-3223(99)00235-8 |
0.433 |
|
| 1999 |
Ikonomov OC, Manji HK. Molecular mechanisms underlying mood stabilization in manic-depressive illness: the phenotype challenge. The American Journal of Psychiatry. 156: 1506-14. PMID 10518159 DOI: 10.1176/Ajp.156.10.1506 |
0.447 |
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| 1999 |
Chen G, Hasanat KA, Bebchuk JM, Moore GJ, Glitz D, Manji HK. Regulation of signal transduction pathways and gene expression by mood stabilizers and antidepressants. Psychosomatic Medicine. 61: 599-617. PMID 10511011 DOI: 10.1097/00006842-199909000-00004 |
0.308 |
|
| 1999 |
Manji HK, Moore GJ, Chen G. Lithium at 50: have the neuroprotective effects of this unique cation been overlooked? Biological Psychiatry. 46: 929-40. PMID 10509176 DOI: 10.1016/S0006-3223(99)00165-1 |
0.436 |
|
| 1999 |
Chen G, Huang LD, Jiang YM, Manji HK. The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3. Journal of Neurochemistry. 72: 1327-30. PMID 10037507 DOI: 10.1046/J.1471-4159.2000.0721327.X |
0.348 |
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| 1999 |
Chen G, Zeng WZ, Yuan PX, Huang LD, Jiang YM, Zhao ZH, Manji HK. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. Journal of Neurochemistry. 72: 879-82. PMID 9930766 DOI: 10.1046/J.1471-4159.1999.720879.X |
0.412 |
|
| 1999 |
Chen G, Yuan PX, Jiang YM, Huang LD, Manji HK. Valproate robustly enhances AP-1 mediated gene expression. Brain Research. Molecular Brain Research. 64: 52-8. PMID 9889318 DOI: 10.1016/S0169-328X(98)00303-9 |
0.331 |
|
| 1998 |
Manji HK, Lenox RH. Lithium: a molecular transducer of mood-stabilization in the treatment of bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 19: 161-6. PMID 9741960 DOI: 10.1016/S0893-133X(98)00021-9 |
0.452 |
|
| 1998 |
Yuan PX, Chen G, Huang LD, Manji HK. Lithium stimulates gene expression through the AP-1 transcription factor pathway. Brain Research. Molecular Brain Research. 58: 225-30. PMID 9685653 DOI: 10.1016/S0169-328X(98)00114-4 |
0.36 |
|
| 1998 |
Chen G, Yuan PX, Jiang YM, Huang LD, Manji HK. Lithium increases tyrosine hydroxylase levels both in vivo and in vitro. Journal of Neurochemistry. 70: 1768-71. PMID 9523597 DOI: 10.1046/J.1471-4159.1998.70041768.X |
0.366 |
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| 1998 |
Moore G, Bebchuk J, Parrish J, Faulk M, Arfken C, Strhl-Bevacqua J, Manji H. 288. Monitoring of lithium induced neurochemical changes in manic depressive illness: In vivo investigation of the inositol depletion hypothesis Biological Psychiatry. 43: S86-S87. DOI: 10.1016/S0006-3223(98)90736-3 |
0.347 |
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| 1997 |
Chen G, Yuan P, Hawver DB, Potter WZ, Manji HK. Increase in AP-1 transcription factor DNA binding activity by valproic acid. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 16: 238-45. PMID 9138440 DOI: 10.1016/S0893-133X(96)00239-4 |
0.325 |
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| 1997 |
Mitchell PB, Manji HK, Chen G, Jolkovsky L, Smith-Jackson E, Denicoff K, Schmidt M, Potter WZ. High levels of Gs alpha in platelets of euthymic patients with bipolar affective disorder. The American Journal of Psychiatry. 154: 218-23. PMID 9016271 DOI: 10.1176/Ajp.154.2.218 |
0.391 |
|
| 1997 |
Ram A, Guedj F, Cravchik A, Weinstein L, Cao Q, Badner JA, Goldin LR, Grisaru N, Manji HK, Belmaker RH, Gershon ES, Gejman PV. No abnormality in the gene for the G protein stimulatory alpha subunit in patients with bipolar disorder. Archives of General Psychiatry. 54: 44-8. PMID 9006399 DOI: 10.1001/Archpsyc.1997.01830130048010 |
0.366 |
|
| 1997 |
Manji HK, Bersudsky Y, Chen G, Belmaker RH, Potter WZ. Modulation of protein kinase C isozymes and substrates by lithium: the role of myo-inositol. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 370-81. PMID 8887991 DOI: 10.1016/0893-133X(95)00243-7 |
0.42 |
|
| 1997 |
Manji HK, Moore GJ, Bebchuk JM, Manji HK. Modulation of brain phosphoinositide signaling by lithium: Relationship to therapeutic response Biological Psychiatry. 42: 290S. DOI: 10.1016/S0006-3223(97)88104-8 |
0.311 |
|
| 1996 |
Chen G, Manji HK, Wright CB, Hawver DB, Potter WZ. Effects of valproic acid on β-adrenergic receptors, G-proteins, and adenylyl cyclase in rat C6 glioma cells Neuropsychopharmacology. 15: 271-280. PMID 8873110 DOI: 10.1016/0893-133X(95)00207-T |
0.311 |
|
| 1996 |
Chen G, Pan B, Hawver DB, Wright CB, Potter WZ, Manji HK. Attenuation of cyclic AMP production by carbamazepine Journal of Neurochemistry. 67: 2079-2086. PMID 8863517 DOI: 10.1046/J.1471-4159.1996.67052079.X |
0.358 |
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| 1996 |
Stein MB, Chen G, Potter WZ, Manji HK. G-protein level quantification in platelets and leukocytes from patients with panic disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 180-6. PMID 8840354 DOI: 10.1016/0893-133X(95)00182-D |
0.303 |
|
| 1996 |
Mitchell P, Manji H, Chen G, Jolkovsky L, Smith-Jackson E, Denicoff K, Schmidt M, Potter W. Increased levels of Gαs in platelets of euthymic bipolar affective disorder patients European Neuropsychopharmacology. 6: 184. DOI: 10.1016/0924-977X(96)88164-8 |
0.378 |
|
| 1996 |
Manji HK. Regulation of transmembrane signalling systems by mood stabilizing agents: Therapeutic implications European Neuropsychopharmacology. 6: 95. DOI: 10.1016/0924-977X(96)87739-X |
0.333 |
|
| 1995 |
Manji HK, Chen G, Shimon H, Hsiao JK, Potter WZ, Belmaker RH. Guanine nucleotide-binding proteins in bipolar affective disorder. Effects of long-term lithium treatment. Archives of General Psychiatry. 52: 135-44. PMID 7848049 DOI: 10.1001/Archpsyc.1995.03950140053007 |
0.446 |
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| 1995 |
Manji HK, Potter WZ, Lenox RH. Signal transduction pathways. Molecular targets for lithium's actions. Archives of General Psychiatry. 52: 531-43. PMID 7598629 DOI: 10.1001/Archpsyc.1995.03950190013003 |
0.482 |
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| 1995 |
Pan B, Manji HK, Schmidt ME, Potter WZ. Carbamazepine increased pregnenolone synthesis blocked by peripheral type benzodiazepine receptor antagonist Depression. 3: 267-272. DOI: 10.1002/Depr.3050030602 |
0.34 |
|
| 1994 |
Rudorfer MV, Manji HK, Potter WZ. Comparative tolerability profiles of the newer versus older antidepressants. Drug Safety. 10: 18-46. PMID 8136085 DOI: 10.2165/00002018-199410010-00003 |
0.341 |
|
| 1994 |
Manji HK, Lenox RH. Long-term action of lithium: a role for transcriptional and posttranscriptional factors regulated by protein kinase C. Synapse (New York, N.Y.). 16: 11-28. PMID 8134897 DOI: 10.1002/syn.890160103 |
0.349 |
|
| 1994 |
Chen G, Manji HK, Hawver DB, Wright CB, Potter WZ. Chronic sodium valproate selectively decreases protein kinase C α and ∈ in vitro Journal of Neurochemistry. 63: 2361-2364. PMID 7964759 DOI: 10.1046/J.1471-4159.1994.63062361.X |
0.347 |
|
| 1994 |
Potter WZ, Manji HK. Catecholamines in depression: an update Clinical Chemistry. 40: 279-287. DOI: 10.1093/clinchem/40.2.279 |
0.318 |
|
| 1993 |
Manji HK, Etcheberrigaray R, Chen G, Olds JL. Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme. Journal of Neurochemistry. 61: 2303-10. PMID 8245981 DOI: 10.1111/J.1471-4159.1993.Tb07474.X |
0.38 |
|
| 1993 |
Manji HK, Chen G, Bitran JA, Gusovsky F, Potter WZ. Idazoxan down-regulates beta-adrenoceptors on C6 glioma cells in vitro. European Journal of Pharmacology. 227: 275-82. PMID 1361912 DOI: 10.1016/0922-4106(92)90005-G |
0.313 |
|
| 1991 |
Potter WZ, Rudorfer MV, Manji H. The pharmacologic treatment of depression. The New England Journal of Medicine. 325: 633-42. PMID 1861697 DOI: 10.1056/Nejm199108293250907 |
0.368 |
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| 1991 |
Risby ED, Hsiao JK, Manji HK, Bitran J, Moses F, Zhou DF, Potter WZ. The Mechanisms of Action of Lithium: II. Effects on Adenylate Cyclase Activity and β-Adrenergic Receptor Binding in Normal Subjects Archives of General Psychiatry. 48: 513-524. PMID 1645514 DOI: 10.1001/Archpsyc.1991.01810300025004 |
0.35 |
|
| 1991 |
Manji HK, Hsiao JK, Risby ED, Oliver J, Rudorfer MV, Potter WZ. The mechanisms of action of lithium. I. Effects on serotoninergic and noradrenergic systems in normal subjects. Archives of General Psychiatry. 48: 505-12. PMID 1645513 DOI: 10.1001/Archpsyc.1991.01810300017003 |
0.315 |
|
| 1990 |
Bitran JA, Potter WZ, Manji HK, Gusovsky F. Chronic Li+ attenuates agonist- and phorbol ester-mediated Na+/H+ antiporter activity in HL-60 cells. European Journal of Pharmacology. 188: 193-202. PMID 2163872 DOI: 10.1016/0922-4106(90)90002-F |
0.318 |
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