| Year |
Citation |
Score |
| 2019 |
Tosin M, Kilgour SL, Jenkins R. A photoactivatable small molecule probe for the in vivo capture of polyketide intermediates. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31617624 DOI: 10.1002/Chem.201903661 |
0.313 |
|
| 2019 |
Alberti F, Leng DJ, Wilkening I, Song L, Tosin M, Corre C. Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery. Chemical Science. 10: 453-463. PMID 30746093 DOI: 10.1039/C8Sc03814G |
0.366 |
|
| 2017 |
Havemann J, Yurkovich ME, Jenkins R, Harringer S, Tao W, Wen S, Sun Y, Leadlay PF, Tosin M. Chemical probing of thiotetronate bio-assembly. Chemical Communications (Cambridge, England). PMID 28119973 DOI: 10.1039/C6Cc09933E |
0.326 |
|
| 2016 |
Tao W, Yurkovich ME, Wen S, Lebe KE, Samborskyy M, Liu Y, Yang A, Liu Y, Ju Y, Deng Z, Tosin M, Sun Y, Leadlay PF. A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis. Chemical Science. 7: 376-385. PMID 28791099 DOI: 10.1039/C5Sc03059E |
0.313 |
|
| 2016 |
Wilkening I, Gazzola S, Riva E, Parascandolo JS, Song L, Tosin M. Second-generation probes for biosynthetic intermediate capture: towards a comprehensive profiling of polyketide assembly. Chemical Communications (Cambridge, England). PMID 27481638 DOI: 10.1039/C6Cc04681A |
0.344 |
|
| 2016 |
Parascandolo JS, Havemann J, Potter HK, Huang F, Riva E, Connolly J, Wilkening I, Song L, Leadlay PF, Tosin M. Insights into 6-Methylsalicylic Acid Bio-assembly by Using Chemical Probes. Angewandte Chemie (International Ed. in English). PMID 26833898 DOI: 10.1002/Anie.201509038 |
0.387 |
|
| 2015 |
Kage H, Riva E, Parascandolo JS, Kreutzer MF, Tosin M, Nett M. Chemical chain termination resolves the timing of ketoreduction in a partially reducing iterative type I polyketide synthase. Organic & Biomolecular Chemistry. 13: 11414-7. PMID 26507693 DOI: 10.1039/C5Ob02009C |
0.311 |
|
| 2014 |
Riva E, Wilkening I, Gazzola S, Li WM, Smith L, Leadlay PF, Tosin M. Chemical probes for the functionalization of polyketide intermediates. Angewandte Chemie (International Ed. in English). 53: 11944-9. PMID 25212788 DOI: 10.1002/Anie.201407448 |
0.402 |
|
| 2011 |
Tosin M, Smith L, Leadlay PF. Insights into lasalocid A ring formation by chemical chain termination in vivo. Angewandte Chemie (International Ed. in English). 50: 11930-3. PMID 22025396 DOI: 10.1002/Anie.201106323 |
0.354 |
|
| 2011 |
Kwan DH, Tosin M, Schläger N, Schulz F, Leadlay PF. Insights into the stereospecificity of ketoreduction in a modular polyketide synthase. Organic & Biomolecular Chemistry. 9: 2053-6. PMID 21340070 DOI: 10.1039/C1Ob00022E |
0.335 |
|
| 2010 |
Dias MV, Huang F, Chirgadze DY, Tosin M, Spiteller D, Dry EF, Leadlay PF, Spencer JB, Blundell TL. Structural basis for the activity and substrate specificity of fluoroacetyl-CoA thioesterase FlK. The Journal of Biological Chemistry. 285: 22495-504. PMID 20430898 DOI: 10.1074/Jbc.M110.107177 |
0.388 |
|
| 2010 |
Tosin M, Betancor L, Stephens E, Li WM, Spencer JB, Leadlay PF. Synthetic chain terminators off-load intermediates from a type I polyketide synthase. Chembiochem : a European Journal of Chemical Biology. 11: 539-46. PMID 20135665 DOI: 10.1002/Cbic.200900772 |
0.343 |
|
| 2010 |
Sun Y, Hahn F, Demydchuk Y, Chettle J, Tosin M, Osada H, Leadlay PF. In vitro reconstruction of tetronate RK-682 biosynthesis. Nature Chemical Biology. 6: 99-101. PMID 20081823 DOI: 10.1038/Nchembio.285 |
0.323 |
|
| 2009 |
André S, Velasco-Torrijos T, Leyden R, Gouin S, Tosin M, Murphy PV, Gabius HJ. Phenylenediamine-based bivalent glycocyclophanes: synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with different glycomic profiles. Organic & Biomolecular Chemistry. 7: 4715-25. PMID 19865709 DOI: 10.1039/B913010A |
0.534 |
|
| 2009 |
Tosin M, Spiteller D, Spencer JB. Malonyl carba(dethia)- and malonyl oxa(dethia)-coenzyme A as tools for trapping polyketide intermediates. Chembiochem : a European Journal of Chemical Biology. 10: 1714-23. PMID 19507202 DOI: 10.1002/Cbic.200900093 |
0.354 |
|
| 2008 |
Loukou C, Tosin M, Müller-Bunz H, Murphy PV. Corrigendum to “Synthesis of sugar-lactams from azides of glucuronic acid” Carbohydrate Research. 343: 412-413. DOI: 10.1016/J.Carres.2007.10.009 |
0.535 |
|
| 2007 |
Loukou C, Tosin M, Müller-Bunz H, Murphy PV. Synthesis of sugar-lactams from azides of glucuronic acid. Carbohydrate Research. 342: 1953-9. PMID 17477912 DOI: 10.1016/J.Carres.2007.04.003 |
0.595 |
|
| 2007 |
Cronin L, Tosin M, Müller-Bunz H, Murphy PV. The synthesis of cyclic imidates from amides of glucuronic acid and investigation of glycosidation reactions. Carbohydrate Research. 342: 111-8. PMID 17123491 DOI: 10.1016/J.Carres.2006.10.023 |
0.59 |
|
| 2007 |
O'Brien C, Poláková M, Pitt N, Tosin M, Murphy PV. Glycosidation-anomerisation reactions of 6,1-anhydroglucopyranuronic acid and anomerisation of beta-D-glucopyranosiduronic acids promoted by SnCl(4). Chemistry (Weinheim An Der Bergstrasse, Germany). 13: 902-9. PMID 17086575 DOI: 10.1002/Chem.200601111 |
0.55 |
|
| 2006 |
Rawe SL, Doyle D, Zaric V, Rozas I, McMahon K, Tosin M, Bunz HM, Murphy EP, O' Boyle KM, Murphy PV. N-Glycosyl-thiophene-2-carboxamides: synthesis, structure and effects on the growth of diverse cell types. Carbohydrate Research. 341: 1370-90. PMID 16716276 DOI: 10.1016/J.Carres.2006.04.041 |
0.553 |
|
| 2005 |
Tosin M, Murphy PV. Synthesis of structurally defined scaffolds for bivalent ligand display based on glucuronic acid anilides. The degree of tertiary amide isomerism and folding depends on the configuration of a glycosyl azide. The Journal of Organic Chemistry. 70: 4107-17. PMID 15876103 DOI: 10.1021/Jo050200Z |
0.58 |
|
| 2005 |
Tosin M, O'Brien C, Fitzpatrick GM, Müller-Bunz H, Glass WK, Murphy PV. Synthesis and structural analysis of the anilides of glucuronic acid and orientation of the groups on the carbohydrate scaffolding. The Journal of Organic Chemistry. 70: 4096-106. PMID 15876102 DOI: 10.1021/Jo0501994 |
0.569 |
|
| 2005 |
Tosin M, Gouin SG, Murphy PV. Synthesis of structurally diverse and defined bivalent mannosides on saccharide scaffolding. Organic Letters. 7: 211-4. PMID 15646960 DOI: 10.1021/Ol047841L |
0.568 |
|
| 2004 |
Poláková M, Pitt N, Tosin M, Murphy PV. Glycosidation reactions of silyl ethers with conformationally inverted donors derived from glucuronic acid: stereoselective synthesis of glycosides and 2-deoxyglycosides. Angewandte Chemie (International Ed. in English). 43: 2518-21. PMID 15127440 DOI: 10.1002/Anie.200353196 |
0.583 |
|
| 2004 |
Tosin M, Müller-Bunz H, Murphy PV. Synthesis and X-ray single crystal structure of a bivalent glycocluster. Chemical Communications (Cambridge, England). 494-5. PMID 14973574 DOI: 10.1039/B313934D |
0.546 |
|
| 2003 |
Murphy PV, Bradley H, Tosin M, Pitt N, Fitzpatrick GM, Glass WK. Development of carbohydrate-based scaffolds for restricted presentation of recognition groups. Extension to divalent ligands and implications for the structure of dimerized receptors. The Journal of Organic Chemistry. 68: 5692-704. PMID 12839465 DOI: 10.1021/Jo034336D |
0.546 |
|
| 2002 |
Tosin M, Murphy PV. Synthesis of alpha-glucuronic acid and amide derivatives in the presence of a participating 2-acyl protecting group. Organic Letters. 4: 3675-8. PMID 12375916 DOI: 10.1021/Ol026629J |
0.522 |
|
| 2002 |
Enright PM, Tosin M, Nieuwenhuyzen M, Cronin L, Murphy PV. A study of the epoxidation of 6-deoxyhex-5-enopyranosides. 1,5-Dicarbonyl derivatives and novel synthetic routes to D-xylo-hexos-5-ulose and D-lyxo-hexos-5-ulose. The Journal of Organic Chemistry. 67: 3733-41. PMID 12027687 DOI: 10.1021/Jo016378C |
0.571 |
|
| 2001 |
O'Brien JL, Tosin M, Murphy PV. Novel synthesis of the glycosidase inhibitor deoxymannojirimycin and of a synthetic precursor D-lyxo-hexos-5-ulose. Organic Letters. 3: 3353-6. PMID 11594832 DOI: 10.1021/Ol016596S |
0.577 |
|
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