| Year |
Citation |
Score |
| 2023 |
Zhang J, Zhou W, Chen Y, Wang Y, Guo Z, Hu W, Li Y, Han X, Si S. Small molecules targeting Pin1 as potent anticancer drugs. Frontiers in Pharmacology. 14: 1073037. PMID 37050909 DOI: 10.3389/fphar.2023.1073037 |
0.331 |
|
| 2021 |
Liu C, Li Y, Sheng R, Han X, Bao L, Wang C, Wang W, Jiang X, Han J, Lei L, Li N, Zhang J, Chen M, Li Y, Wu Y, ... ... Si S, et al. Synthesis of N-methylpyridine-chlorofuranformamide analogs as novel OPG up-regulators and inhibitors of RANKL-induced osteoclastogenesis. Bioorganic Chemistry. 116: 105361. PMID 34562672 DOI: 10.1016/j.bioorg.2021.105361 |
0.334 |
|
| 2021 |
Xu Y, Liu C, Han X, Jia X, Li Y, Liu C, Li N, Liu L, Liu P, Jiang X, Wang W, Wang X, Li Y, Chen M, Luo J, ... ... Si S, et al. E17241 as a Novel ABCA1 (ATP-Binding Cassette Transporter A1) Upregulator Ameliorates Atherosclerosis in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314156. PMID 33441025 DOI: 10.1161/ATVBAHA.120.314156 |
0.616 |
|
| 2020 |
Zhen X, Mao MJ, Wang RZ, Chang SS, Xiao TM, Wu YX, Yu LY, Song YL, Chen MH, Si SY. Fusapyrone A, a -pyrone derived from a desert sp. Journal of Asian Natural Products Research. 1-8. PMID 32762359 DOI: 10.1080/10286020.2020.1794857 |
0.337 |
|
| 2020 |
Li Y, Zhu X, Zhang J, Lin Y, You X, Chen M, Wang Y, Zhu N, Si S. Identification of a Compound That Inhibits the Growth of Gram-Negative Bacteria by Blocking BamA-BamD Interaction. Frontiers in Microbiology. 11: 1252. PMID 32636816 DOI: 10.3389/Fmicb.2020.01252 |
0.328 |
|
| 2020 |
Wang X, Chen X, Zhang X, Su C, Yang M, He W, Du Y, Si S, Wang L, Hong B. A small-molecule inhibitor of PCSK9 transcription ameliorates atherosclerosis through the modulation of FoxO1/3 and HNF1α. Ebiomedicine. 52: 102650. PMID 32058941 DOI: 10.1016/J.Ebiom.2020.102650 |
0.351 |
|
| 2020 |
Luo J, Wang X, Jiang X, Liu C, Li Y, Han X, Zuo X, Li Y, Li N, Xu Y, Si S. Rutaecarpine derivative R3 attenuates atherosclerosis via inhibiting NLRP3 inflammasome-related inflammation and modulating cholesterol transport. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 1398-1411. PMID 31914630 DOI: 10.1096/Fj.201900903Rrr |
0.63 |
|
| 2020 |
Liu J, Jia X, Zhao J, Feng J, Chen M, Chen R, Xie K, Chen D, Li Y, Zhang D, Peng Y, Si S, Dai J. Bistachybotrysins L–V, bioactive phenylspirodrimane dimers from the fungus Stachybotrys chartarum Organic Chemistry Frontiers. 7: 531-542. DOI: 10.1039/C9Qo01284B |
0.373 |
|
| 2019 |
Jia XJ, Du Y, Jiang HJ, Li YZ, Xu YN, Si SY, Wang L, Hong B. Identification of Novel Compounds Enhancing SR-BI mRNA Stability through High-Throughput Screening. Slas Discovery : Advancing Life Sciences R & D. 2472555219894543. PMID 31858876 DOI: 10.1177/2472555219894543 |
0.648 |
|
| 2019 |
Li Y, Sun H, Zhu X, Bian C, Wang Y, Si S. Identification of New Antifungal Agents Targeting Chitin Synthesis by a Chemical-Genetic Method. Molecules (Basel, Switzerland). 24. PMID 31470665 DOI: 10.3390/Molecules24173155 |
0.405 |
|
| 2019 |
Lin Y, Zhang H, Song W, Si S, Han Y, Jiang J. Identification and characterization of Zika virus NS5 RNA-dependent RNA polymerase inhibitors. International Journal of Antimicrobial Agents. PMID 31310806 DOI: 10.1016/J.Ijantimicag.2019.07.010 |
0.323 |
|
| 2019 |
Han X, Gong S, Li N, Wang X, Liu P, Xu Y, He X, Jiang W, Si S. A Novel Small Molecule Which Increases Osteoprotegerin Expression and Protects Against Ovariectomy-Related Bone Loss in Rats. Frontiers in Pharmacology. 10: 103. PMID 30914947 DOI: 10.3389/Fphar.2019.00103 |
0.337 |
|
| 2019 |
Fu HG, Li ZW, Hu XX, Si SY, You XF, Tang S, Wang YX, Song DQ. Synthesis and Biological Evaluation of Quinoline Derivatives as a Novel Class of Broad-Spectrum Antibacterial Agents. Molecules (Basel, Switzerland). 24. PMID 30717338 DOI: 10.3390/Molecules24030548 |
0.381 |
|
| 2019 |
Wang F, Zhao W, Zhang C, Chang S, Shao R, Xing J, Chen M, Zhang Y, Si S. Cytotoxic metabolites from the endophytic fungus Chaetomium globosum 7951 Rsc Advances. 9: 16035-16039. DOI: 10.1039/C9Ra02647A |
0.372 |
|
| 2019 |
Xue S, Wang Y, Han X, Yi H, Jiang W, Si S, Guo H, Li Z. Novel cathepsin K inhibitors block osteoclasts in vitro and increase spinal bone density in zebrafish Rsc Advances. 9: 8600-8607. DOI: 10.1039/C8Ra10338K |
0.316 |
|
| 2018 |
Zhu N, Wang X, Li D, Lin Y, You X, Jiang J, Xu Y, Jiang W, Si S. IMB-T130 targets 3-dehydroquinate synthase and inhibits Mycobacterium tuberculosis. Scientific Reports. 8: 17439. PMID 30487577 DOI: 10.1038/S41598-018-35701-Z |
0.328 |
|
| 2018 |
Zhang X, Li Y, Wang W, Zhang J, Lin Y, Hong B, You X, Song D, Wang Y, Jiang J, Si S. Identification of an anti-Gram-negative bacteria agent disrupting the interaction between LPS transporters LptA and LptC. International Journal of Antimicrobial Agents. PMID 30476569 DOI: 10.1016/J.Ijantimicag.2018.11.016 |
0.326 |
|
| 2018 |
Wang W, Liu C, Zhu N, Lin Y, Jiang J, Wang Y, Li Y, Si S. Identification of anti-Gram-negative bacteria agents targeting the interaction between ribosomal proteins L12 and L10. Acta Pharmaceutica Sinica. B. 8: 772-783. PMID 30245964 DOI: 10.1016/J.Apsb.2018.07.006 |
0.332 |
|
| 2018 |
Wang X, Luo J, Li N, Liu L, Han X, Liu C, Zuo X, Jiang X, Li Y, Xu Y, Si S. E3317 promotes cholesterol efflux in macrophage cells via enhancing ABCA1 expression. Biochemical and Biophysical Research Communications. PMID 30173890 DOI: 10.1016/J.Bbrc.2018.08.125 |
0.458 |
|
| 2018 |
Feng T, Liu P, Wang X, Luo J, Zuo X, Jiang X, Liu C, Li Y, Li N, Chen M, Zhu N, Han X, Liu C, Xu Y, Si S. SIRT1 activator E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression. Atherosclerosis. 274: 172-181. PMID 29787963 DOI: 10.1016/J.Atherosclerosis.2018.04.039 |
0.634 |
|
| 2018 |
Lin Y, Zhang H, Zhu N, Wang X, Han Y, Chen M, Jiang J, Si S. Identification of TB-E12 as a novel FtsZ inhibitor with anti-tuberculosis activity. Tuberculosis (Edinburgh, Scotland). 110: 79-85. PMID 29779778 DOI: 10.1016/J.Tube.2018.04.002 |
0.315 |
|
| 2018 |
Liu P, Feng T, Zuo X, Wang X, Luo J, Li N, Han X, Zhu N, Xu S, Xu Y, Jin ZG, Si S. A novel SIRT1 activator E6155 improves insulin sensitivity in type 2 diabetic KKAmice. Biochemical and Biophysical Research Communications. PMID 29524414 DOI: 10.1016/J.Bbrc.2018.03.034 |
0.303 |
|
| 2018 |
Gong J, Zheng Y, Wang Y, Sheng W, Li Y, Liu X, Si S, Shao R, Zhen Y. A new compound of thiophenylated pyridazinone IMB5043 showing potent antitumor efficacy through ATM-Chk2 pathway. Plos One. 13: e0191984. PMID 29394294 DOI: 10.1371/Journal.Pone.0191984 |
0.41 |
|
| 2017 |
Si S, Feng T, Liu P, Wang X, Liu C, Li N, Zhu N, Chen M, Li Y, Han X, Liu C, Xu Y. E1231, an activator of SIRT1, regulates cholesterol and lipid metabolism through SIRT1-LXRALPHA-ABCA1 pathway. Atherosclerosis. 263: e75. PMID 29366216 DOI: 10.1016/J.Atherosclerosis.2017.06.248 |
0.61 |
|
| 2017 |
Xu Y, Xu S, Liu P, Koroleva M, Zhang S, Si S, Jin ZG. Suberanilohydroxamic Acid as a Pharmacological Kruppel-Like Factor 2 Activator That Represses Vascular Inflammation and Atherosclerosis. Journal of the American Heart Association. 6. PMID 29191808 DOI: 10.1161/Jaha.117.007134 |
0.3 |
|
| 2017 |
Chang SS, Chen MH, Wang RZ, Wu YX, Yang GH, Dong B, Yu LY, Gao ZP, Si SY. [A new benzamide derivative from rice fermentation of Streptomyces sp. CPCC 202950]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 42: 2097-2101. PMID 28822154 DOI: 10.19540/J.Cnki.Cjcmm.2017.0093 |
0.367 |
|
| 2017 |
Xu Y, Liu P, Xu S, Koroleva M, Zhang S, Si S, Jin ZG. Tannic acid as a plant-derived polyphenol exerts vasoprotection via enhancing KLF2 expression in endothelial cells. Scientific Reports. 7: 6686. PMID 28751752 DOI: 10.1038/S41598-017-06803-X |
0.376 |
|
| 2017 |
Li N, Wang X, Xu Y, Lin Y, Zhu N, Liu P, Lu D, Si S. Identification of a novel liver X receptor agonist that regulates the expression of key cholesterol homeostasis genes with distinct pharmacological characteristics. Molecular Pharmacology. PMID 28087808 DOI: 10.1124/mol.116.105213 |
0.369 |
|
| 2016 |
Yang SS, Xu YN, Liu P, Wang X, Han XW, Fan ZW, Si SY. [In vitro effect and mechanistic study of compound E23869 on lipid metabolism]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 51: 563-72. PMID 29859525 |
0.368 |
|
| 2016 |
Chen Y, Zhang J, Li D, Jiang J, Wang Y, Si S. Identification of a novel Polo-like kinase 1 inhibitor that specifically blocks the functions of Polo-Box domain. Oncotarget. PMID 27902479 DOI: 10.18632/Oncotarget.13603 |
0.339 |
|
| 2016 |
Gong S, Han X, Li X, Yang J, He X, Si S. Development of a High-Throughput Screening Strategy for Upregulators of the OPG/RANKL Ratio with the Potential for Antiosteoporosis Effects. Journal of Biomolecular Screening. PMID 27301430 DOI: 10.1177/1087057116654657 |
0.418 |
|
| 2016 |
Li N, Wang X, Liu P, Lu D, Jiang W, Xu Y, Si S. E17110 promotes reverse cholesterol transport with liver X receptor β agonist activity in vitro. Acta Pharmaceutica Sinica. B. 6: 198-204. PMID 27175330 DOI: 10.1016/J.Apsb.2016.03.005 |
0.461 |
|
| 2016 |
Shi Y, Jiang Z, Lei X, Zhang N, Cai Q, Li Q, Wang L, Si S, Xie Y, Hong B. Improving the N-terminal diversity of sansanmycin through mutasynthesis. Microbial Cell Factories. 15: 77. PMID 27154005 DOI: 10.1186/S12934-016-0471-1 |
0.301 |
|
| 2016 |
Zhang J, Han XM, Hu WH, Guo ZR, He XB, Si SY. [Application of temperature sensitive yeast models with definite target in the screening of potential human Pin1 inhibitors]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 49: 854-60. PMID 25212032 |
0.302 |
|
| 2015 |
Jiang H, Zhang J, Du Y, Jia X, Yang F, Si S, Wang L, Hong B. microRNA-185 modulates low density lipoprotein receptor expression as a key posttranscriptional regulator. Atherosclerosis. 243: 523-532. PMID 26523989 DOI: 10.1016/J.Atherosclerosis.2015.10.026 |
0.367 |
|
| 2015 |
Li D, Gao N, Zhu N, Lin Y, Li Y, Chen M, You X, Lu Y, Wan K, Jiang JD, Jiang W, Si S. Discovery of the disubstituted oxazole analogues as a novel class anti-tuberculotic agents against MDR- and XDR-MTB. Bioorganic & Medicinal Chemistry Letters. PMID 26459210 DOI: 10.1016/J.Bmcl.2015.09.072 |
0.4 |
|
| 2015 |
Liu C, Feng T, Zhu N, Liu P, Han X, Chen M, Wang X, Li N, Li Y, Xu Y, Si S. Corrigendum: Identification of a novel selective agonist of PPARγ with no promotion of adipogenesis and less inhibition of osteoblastogenesis. Scientific Reports. 5: 12185. PMID 26244753 DOI: 10.1038/srep12185 |
0.565 |
|
| 2015 |
Wang X, Liu C, Liu P, Li N, Xu YN, Si SY. [The in vitro anti-atherosclerotic activity of compound E0869]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 50: 440-6. PMID 26223125 |
0.371 |
|
| 2015 |
Chen MH, Wu YX, Xu YN, Liu P, Yu LY, Hong B, Jiang W, Si SY. A new trichostatin analog from Streptomyces sp. CPCC 203909. Journal of Asian Natural Products Research. 17: 676-82. PMID 25977996 DOI: 10.1080/10286020.2015.1042372 |
0.341 |
|
| 2015 |
Liu C, Feng T, Zhu N, Liu P, Han X, Chen M, Wang X, Li N, Li Y, Xu Y, Si S. Identification of a novel selective agonist of PPARγ with no promotion of adipogenesis and less inhibition of osteoblastogenesis. Scientific Reports. 5: 9530. PMID 25827822 DOI: 10.1038/Srep09530 |
0.626 |
|
| 2015 |
Du Y, Wang L, Si S, Yang Y, Hong B. A novel compound 4010B-30 upregulates apolipoprotein A-I gene expression through activation of PPARγ in HepG2 cells. Atherosclerosis. 239: 589-98. PMID 25734982 DOI: 10.1016/J.Atherosclerosis.2015.02.030 |
0.39 |
|
| 2015 |
Chen M, Wu Y, He Y, Xu Y, Li Y, Li D, Feng T, Yu L, Hong B, Jiang W, Si S. Identification of trichostatin derivatives from Streptomyces sp. CPCC 203909. Bioorganic & Medicinal Chemistry Letters. 25: 562-5. PMID 25556102 DOI: 10.1016/J.Bmcl.2014.12.030 |
0.632 |
|
| 2014 |
Li N, Wang X, Zhang J, Liu C, Li Y, Feng T, Xu Y, Si S. Identification of a novel partial agonist of liver X receptor α (LXRα) via screening. Biochemical Pharmacology. 92: 438-47. PMID 25450668 DOI: 10.1016/J.Bcp.2014.09.017 |
0.683 |
|
| 2014 |
Feng TT, Li YZ, Li N, Liu C, Wang X, Xu YN, Si SY. [The in vitro anti-atherosclerotic activity of compound IMB-1680]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 49: 602-7. PMID 25151728 |
0.628 |
|
| 2014 |
Li Y, Feng T, Liu P, Liu C, Wang X, Li D, Li N, Chen M, Xu Y, Si S. Optimization of Rutaecarpine as ABCA1 Up-Regulator for Treating Atherosclerosis. Acs Medicinal Chemistry Letters. 5: 884-8. PMID 25147608 DOI: 10.1021/Ml500131A |
0.647 |
|
| 2014 |
Lin Y, Zhu N, Han Y, Jiang J, Si S. Identification of anti-tuberculosis agents that target the cell-division protein FtsZ. The Journal of Antibiotics. 67: 671-6. PMID 24984796 DOI: 10.1038/Ja.2014.89 |
0.335 |
|
| 2014 |
Xu Y, Liu Q, Xu Y, Liu C, Wang X, He X, Zhu N, Liu J, Wu Y, Li Y, Li N, Feng T, Lai F, Zhang M, Hong B, ... ... Si S, et al. Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through upregulating ABCA1 and SR-BI within RCT. Journal of Lipid Research. 55: 1634-1647. PMID 24908654 DOI: 10.1194/jlr.M044198 |
0.62 |
|
| 2014 |
Li Y, Zhang X, Zhang J, Li Y, Liu W, Wang Z, Wang Y, Si S. A small molecule, MTBT, prevents cancer cell growth by activating p38 MAPK. Anti-Cancer Drugs. 25: 423-32. PMID 24441745 DOI: 10.1097/Cad.0000000000000074 |
0.614 |
|
| 2014 |
Li N, Xu Y, Feng T, Liu C, Li Y, Wang X, Si S. Identification of a selective agonist for liver X receptor α (LXRα) via screening of a synthetic compound library. Journal of Biomolecular Screening. 19: 566-74. PMID 24334278 DOI: 10.1177/1087057113516004 |
0.675 |
|
| 2013 |
Chen JJ, Zhang NF, Mao GX, He XB, Zhan YC, Deng HB, Song DQ, Li DD, Li ZR, Si SY, Qiu Q, Wang Z. Salidroside stimulates osteoblast differentiation through BMP signaling pathway. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 62: 499-505. PMID 24055767 DOI: 10.1016/J.Fct.2013.09.019 |
0.354 |
|
| 2013 |
Kobayashi K, Ohshiro T, Matsuda D, Jiang W, Hong B, Si S, Tomoda H. The mechanism of action of bufalin in inhibition of lipid droplet accumulation in mouse macrophages. Biological & Pharmaceutical Bulletin. 36: 364-9. PMID 23449325 DOI: 10.1248/Bpb.B12-00722 |
0.409 |
|
| 2012 |
Liu X, Gan M, Dong B, Zhang T, Li Y, Zhang Y, Fan X, Wu Y, Bai S, Chen M, Yu L, Tao P, Jiang W, Si S. 4862F, a new inhibitor of HIV-1 protease, from the culture of Streptomyces I03A-04862. Molecules (Basel, Switzerland). 18: 236-43. PMID 23271463 DOI: 10.3390/Molecules18010236 |
0.573 |
|
| 2012 |
Han X, Zhang J, Guo L, Cao R, Li Y, Li N, Ma Q, Wu J, Wang Y, Si S. A series of beta-carboline derivatives inhibit the kinase activity of PLKs. Plos One. 7: e46546. PMID 23056340 DOI: 10.1371/Journal.Pone.0046546 |
0.641 |
|
| 2012 |
Lin Y, Li Y, Zhu Y, Zhang J, Li Y, Liu X, Jiang W, Yu S, You XF, Xiao C, Hong B, Wang Y, Jiang JD, Si S. Identification of antituberculosis agents that target ribosomal protein interactions using a yeast two-hybrid system. Proceedings of the National Academy of Sciences of the United States of America. 109: 17412-7. PMID 23045703 DOI: 10.1073/Pnas.1110271109 |
0.587 |
|
| 2012 |
Wang Y, Qiu Q, Shen JJ, Li DD, Jiang XJ, Si SY, Shao RG, Wang Z. Cardiac glycosides induce autophagy in human non-small cell lung cancer cells through regulation of dual signaling pathways. The International Journal of Biochemistry & Cell Biology. 44: 1813-24. PMID 22750415 DOI: 10.1016/J.Biocel.2012.06.028 |
0.359 |
|
| 2012 |
Du Y, Yang Y, Jiang W, Wang L, Jia XJ, Si SY, Chen XF, Hong B. Substituted benzamides containing azaspiro rings as upregulators of apolipoprotein A-I transcription. Molecules (Basel, Switzerland). 17: 7379-86. PMID 22699570 DOI: 10.3390/Molecules17067379 |
0.42 |
|
| 2012 |
Bao Y, Wang L, Xu Y, Yang Y, Wang L, Si S, Cho S, Hong B. Salvianolic acid B inhibits macrophage uptake of modified low density lipoprotein (mLDL) in a scavenger receptor CD36-dependent manner. Atherosclerosis. 223: 152-9. PMID 22658257 DOI: 10.1016/J.Atherosclerosis.2012.05.006 |
0.354 |
|
| 2012 |
Liu J, Zhang Z, Xu Y, Feng T, Jiang W, Li Z, Hong B, Xie Z, Si S. IMB2026791, a xanthone, stimulates cholesterol efflux by increasing the binding of apolipoprotein A-I to ATP-binding cassette transporter A1. Molecules (Basel, Switzerland). 17: 2833-54. PMID 22399138 DOI: 10.3390/Molecules17032833 |
0.47 |
|
| 2011 |
Xu Y, Lai F, Xu Y, Wu Y, Liu Q, Li N, Wei Y, Feng T, Zheng Z, Jiang W, Yu L, Hong B, Si S. Mycophenolic acid induces ATP-binding cassette transporter A1 (ABCA1) expression through the PPARγ-LXRα-ABCA1 pathway. Biochemical and Biophysical Research Communications. 414: 779-82. PMID 22005457 DOI: 10.1016/J.Bbrc.2011.10.002 |
0.436 |
|
| 2011 |
Zheng Z, Yang Y, Shao H, Liu Z, Lu X, Xu Y, He X, Jiang W, Jiang Q, Zhao B, Zhang H, Li Z, Si S. Two thiophenes compounds are partial peroxisome proliferator-activated receptor α/γ dual agonists. Biological & Pharmaceutical Bulletin. 34: 1631-4. PMID 21963508 DOI: 10.1248/Bpb.34.1631 |
0.366 |
|
| 2011 |
Xu Y, Xu Y, Bao Y, Hong B, Si S. Identification of dehydroxytrichostatin A as a novel up-regulator of the ATP-binding cassette transporter A1 (ABCA1). Molecules (Basel, Switzerland). 16: 7183-98. PMID 21869747 DOI: 10.3390/Molecules16097183 |
0.451 |
|
| 2011 |
Gan M, Zheng X, Gan L, Guan Y, Hao X, Liu Y, Si S, Zhang Y, Yu L, Xiao C. Streptothricin derivatives from Streptomyces sp. I08A 1776. Journal of Natural Products. 74: 1142-7. PMID 21510638 DOI: 10.1021/Np2000733 |
0.338 |
|
| 2011 |
Zheng ZH, Yang Y, Lu XH, Zhang H, Shui XX, Liu C, He XB, Jiang Q, Zhao BH, Si SY. Mycophenolic acid induces adipocyte-like differentiation and reversal of malignancy of breast cancer cells partly through PPARγ. European Journal of Pharmacology. 658: 1-8. PMID 21349264 DOI: 10.1016/J.Ejphar.2011.01.068 |
0.348 |
|
| 2011 |
Wang YX, Wang L, Xu YN, Li YH, Jiang JD, Si SY, Li YB, Ren G, Shan YQ, Hong B, Song DQ. Synthesis and structure-activity relationship of N-(2-arylethyl) isoquinoline derivatives as human scavenger receptor CD36 antagonists. European Journal of Medicinal Chemistry. 46: 1066-73. PMID 21295889 DOI: 10.1016/J.Ejmech.2011.01.022 |
0.345 |
|
| 2010 |
Yang Y, Wang L, Si S, Hong B. How can high-throughput screening deliver drugs to treat atherosclerosis? Expert Opinion On Drug Discovery. 5: 1175-88. PMID 22822720 DOI: 10.1517/17460441.2010.529896 |
0.325 |
|
| 2010 |
Xu Y, Wang J, Bao Y, Jiang W, Zuo L, Song D, Hong B, Si S. Identification of two antagonists of the scavenger receptor CD36 using a high-throughput screening model. Analytical Biochemistry. 400: 207-12. PMID 20152792 DOI: 10.1016/J.Ab.2010.02.003 |
0.422 |
|
| 2010 |
Wang L, Bao Y, Yang Y, Wu Y, Chen X, Si S, Hong B. Discovery of antagonists for human scavenger receptor CD36 via an ELISA-like high-throughput screening assay. Journal of Biomolecular Screening. 15: 239-50. PMID 20150587 DOI: 10.1177/1087057109359686 |
0.361 |
|
| 2010 |
Guo H, Shao H, Yang Z, Xue S, Li X, Liu Z, He X, Jiang J, Zhang Y, Si S, Li Z. Substituted benzothiophene or benzofuran derivatives as a novel class of bone morphogenetic protein-2 up-regulators: synthesis, structure-activity relationships, and preventive bone loss efficacies in senescence accelerated mice (SAMP6) and ovariectomized rats. Journal of Medicinal Chemistry. 53: 1819-1829. PMID 20088515 DOI: 10.1021/Jm901685N |
0.338 |
|
| 2010 |
Zheng Z, Lu X, Zhang H, Lv G, He J, Zhao B, Si S. Impacts of different promoters on the mammalian one-hybrid assay for detecting nuclear receptor agonists. Analytical and Bioanalytical Chemistry. 396: 1721-1730. PMID 20082234 DOI: 10.1007/S00216-009-3391-7 |
0.322 |
|
| 2009 |
Zhang J, Li Y, Guo L, Cao R, Zhao P, Jiang W, Ma Q, Yi H, Li Z, Jiang J, Wu J, Wang Y, Si S. DH166, a beta-carboline derivative, inhibits the kinase activity of PLK1. Cancer Biology & Therapy. 8: 2374-83. PMID 19855194 DOI: 10.4161/Cbt.8.24.10182 |
0.358 |
|
| 2009 |
Li X, Yang J, He X, Yang Z, Ding Y, Zhao P, Liu Z, Shao H, Li Z, Zhang Y, Si S. Identification of upregulators of BMP2 expression via high-throughput screening of a synthetic and natural compound library. Journal of Biomolecular Screening. 14: 1251-6. PMID 19773586 DOI: 10.1177/1087057109346446 |
0.385 |
|
| 2009 |
Matsuda D, Ohshiro T, Ohba M, Jiang W, Hong B, Si S, Tomoda H. The molecular target of rubimaillin in the inhibition of lipid droplet accumulation in macrophages. Biological & Pharmaceutical Bulletin. 32: 1317-20. PMID 19652367 DOI: 10.1248/Bpb.32.1317 |
0.407 |
|
| 2009 |
Yang Y, Jiang W, Wang L, Zhang ZB, Si SY, Hong B. Characterization of the isoflavone pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells. Biological & Pharmaceutical Bulletin. 32: 1289-94. PMID 19571401 DOI: 10.1248/Bpb.32.1289 |
0.427 |
|
| 2009 |
Liu Z, He X, Yang Z, Shao H, Li X, Guo H, Zhang Y, Si S, Li Z. Synthesis and evaluation of 1-(benzo[b]thiophen-2-yl)ethanone analogues as novel anti-osteoporosis agents acting on BMP-2 promotor. Bioorganic & Medicinal Chemistry Letters. 19: 4167-4170. PMID 19524435 DOI: 10.1016/J.Bmcl.2009.05.118 |
0.344 |
|
| 2009 |
Bao Y, Yang Y, Wang L, Gao L, Jiang W, Wang L, Si S, Hong B. Identification of trichostatin A as a novel transcriptional up-regulator of scavenger receptor BI both in HepG2 and RAW 264.7 cells. Atherosclerosis. 204: 127-35. PMID 18930459 DOI: 10.1016/J.Atherosclerosis.2008.08.041 |
0.44 |
|
| 2009 |
Shao H, Li D, Yang Y, Guo H, Liu Z, Si S, Yang Z, Li Z. The effect of substituted thiophene and benzothiophene derivates on PPARγ expression and glucose metabolism Journal of Enzyme Inhibition and Medicinal Chemistry. 25: 282-289. DOI: 10.3109/14756360903179369 |
0.359 |
|
| 2008 |
Fu DH, Jiang W, Zheng JT, Zhao GY, Li Y, Yi H, Li ZR, Jiang JD, Yang KQ, Wang Y, Si SY. Jadomycin B, an Aurora-B kinase inhibitor discovered through virtual screening. Molecular Cancer Therapeutics. 7: 2386-93. PMID 18723485 DOI: 10.1158/1535-7163.Mct-08-0035 |
0.313 |
|
| 2008 |
Gao J, Xu Y, Yang Y, Yang Y, Zheng Z, Jiang W, Hong B, Yan X, Si S. Identification of upregulators of human ATP-binding cassette transporter A1 via high-throughput screening of a synthetic and natural compound library. Journal of Biomolecular Screening. 13: 648-56. PMID 18594022 DOI: 10.1177/1087057108320545 |
0.452 |
|
| 2008 |
Matsuda D, Ohte S, Ohshiro T, Jiang W, Rudel L, Hong B, Si S, Tomoda H. Molecular target of piperine in the inhibition of lipid droplet accumulation in macrophages. Biological & Pharmaceutical Bulletin. 31: 1063-6. PMID 18520030 DOI: 10.1248/Bpb.31.1063 |
0.409 |
|
| 2007 |
Zheng ZH, Dong YS, Zhang H, Lu XH, Ren X, Zhao G, He JG, Si SY. Isolation and characterization of N98-1272 A, B and C, selective acetylcholinesterase inhibitors from metabolites of an actinomycete strain. Journal of Enzyme Inhibition and Medicinal Chemistry. 22: 43-9. PMID 17373546 DOI: 10.1080/14756360600988781 |
0.337 |
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| 2007 |
Yang Y, Zhang Z, Jiang W, Gao L, Zhao G, Zheng Z, Wang M, Si S, Hong B. Identification of novel human high-density lipoprotein receptor Up-regulators using a cell-based high-throughput screening assay. Journal of Biomolecular Screening. 12: 211-9. PMID 17259591 DOI: 10.1177/1087057106297568 |
0.462 |
|
| 2007 |
Li Y, Liang F, Jiang W, Yu F, Cao R, Ma Q, Dai X, Jiang J, Wang Y, Si S. DH334, a β-carboline anti-cancer drug, Inhibits the CDK activity of budding yeast Cancer Biology & Therapy. 6: 1193. DOI: 10.4161/Cbt.6.8.4382 |
0.33 |
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| 2006 |
Cheng C, Liu Q, Chen L, Jin W, Si S, Li D. Isolation, structure determination and biological activity of a new glutarimide antibiotic, S632A3. Journal of Asian Natural Products Research. 8: 55-60. PMID 16753783 DOI: 10.1080/10286020500382884 |
0.322 |
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| 2004 |
Kong W, Wei J, Abidi P, Lin M, Inaba S, Li C, Wang Y, Wang Z, Si S, Pan H, Wang S, Wu J, Wang Y, Li Z, Liu J, et al. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nature Medicine. 10: 1344-51. PMID 15531889 DOI: 10.1038/Nm1135 |
0.4 |
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