André E. Nel, MD PhD - Publications

Affiliations: 
David Geffen School of Medicine University of California, Los Angeles, Los Angeles, CA 
 California NanoSystems Institute University of California, Los Angeles, Los Angeles, CA 
Area:
NanoMedicine
Website:
https://cnsi.ucla.edu/andre-nel-bio/

170 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chattopadhyay S, Liao YP, Wang X, Nel AE. Use of Stromal Intervention and Exogenous Neoantigen Vaccination to Boost Pancreatic Cancer Chemo-Immunotherapy by Nanocarriers. Bioengineering (Basel, Switzerland). 10. PMID 37892935 DOI: 10.3390/bioengineering10101205  0.807
2023 Luo L, Wang X, Liao YP, Chang CH, Nel AE. Correction to "Nanocarrier Co-formulation for Delivery of a TLR7 Agonist plus an Immunogenic Cell Death Stimulus Triggers Effective Pancreatic Cancer Chemo-immunotherapy". Acs Nano. PMID 37504218 DOI: 10.1021/acsnano.3c06667  0.789
2023 Xu X, Wang X, Liao YP, Luo L, Xia T, Nel AE. Use of a Liver-Targeting Immune-Tolerogenic mRNA Lipid Nanoparticle Platform to Treat Peanut-Induced Anaphylaxis by Single- and Multiple-Epitope Nucleotide Sequence Delivery. Acs Nano. PMID 36853930 DOI: 10.1021/acsnano.2c12420  0.803
2022 Li J, Diamante G, Ahn IS, Wijaya D, Wang X, Chang CH, Ha SM, Immadisetty K, Meng H, Nel A, Yang X, Xia T. Determination of the nanoparticle- and cell-specific toxicological mechanisms in 3D liver spheroids using scRNAseq analysis. Nano Today. 47. PMID 36911538 DOI: 10.1016/j.nantod.2022.101652  0.816
2022 Luo L, Wang X, Liao YP, Chang CH, Nel AE. Nanocarrier Co-formulation for Delivery of a TLR7 Agonist plus an Immunogenic Cell Death Stimulus Triggers Effective Pancreatic Cancer Chemo-immunotherapy. Acs Nano. PMID 35920660 DOI: 10.1021/acsnano.2c06300  0.807
2022 Nel AE, Mei KC, Liao YP, Liu X. Multifunctional Lipid Bilayer Nanocarriers for Cancer Immunotherapy in Heterogeneous Tumor Microenvironments, Combining Immunogenic Cell Death Stimuli with Immune Modulatory Drugs. Acs Nano. PMID 35348320 DOI: 10.1021/acsnano.2c01252  0.8
2021 Liu Q, Wang X, Liao YP, Chang CH, Li J, Xia T, Nel AE. Use of a Liver-targeting Nanoparticle Platform to Intervene in Peanut-induced anaphylaxis through delivery of an Ara h2 T-cell Epitope. Nano Today. 42. PMID 36969911 DOI: 10.1016/j.nantod.2021.101370  0.802
2021 Li J, Guiney LM, Downing JR, Wang X, Chang CH, Jiang J, Liu Q, Liu X, Mei KC, Liao YP, Ma T, Meng H, Hersam MC, Nel AE, Xia T. Dissolution of 2D Molybdenum Disulfide Generates Differential Toxicity among Liver Cell Types Compared to Non-Toxic 2D Boron Nitride Effects. Small (Weinheim An Der Bergstrasse, Germany). e2101084. PMID 34032006 DOI: 10.1002/smll.202101084  0.788
2021 Lu J, Liu X, Liao YP, Wang X, Ahmed A, Jiang W, Ji Y, Meng H, Nel AE. Retraction of "Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway". Acs Nano. 15: 10735. PMID 34018715 DOI: 10.1021/acsnano.0c08653  0.779
2021 Liu X, Jiang J, Liao YP, Tang I, Zheng E, Qiu W, Lin M, Wang X, Ji Y, Mei KC, Liu Q, Chang CH, Wainberg ZA, Nel AE, Meng H. Combination Chemo-Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti-PD-1. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 8: 2002147. PMID 33747719 DOI: 10.1002/advs.202002147  0.79
2021 Liu X, Jiang J, Chang CH, Liao YP, Lodico JJ, Tang I, Zheng E, Qiu W, Lin M, Wang X, Ji Y, Mei KC, Nel AE, Meng H. Development of Facile and Versatile Platinum Drug Delivering Silicasome Nanocarriers for Efficient Pancreatic Cancer Chemo-Immunotherapy. Small (Weinheim An Der Bergstrasse, Germany). e2005993. PMID 33682329 DOI: 10.1002/smll.202005993  0.81
2020 Allen SD, Liu X, Jiang J, Liao YP, Chang CH, Nel AE, Meng H. Immune checkpoint inhibition in syngeneic mouse cancer models by a silicasome nanocarrier delivering a GSK3 inhibitor. Biomaterials. 269: 120635. PMID 33422940 DOI: 10.1016/j.biomaterials.2020.120635  0.788
2020 Liu Q, Wang X, Liu X, Liao YP, Chang CH, Mei KC, Jiang J, Tseng S, Gochman G, Huang M, Thatcher Z, Li J, Allen SD, Lucido L, Xia T, ... Nel AE, et al. Antigen- and Epitope-Delivering Nanoparticles Targeting Liver Induce Comparable Immunotolerance in Allergic Airway Disease and Anaphylaxis as Nanoparticle-Delivering Pharmaceuticals. Acs Nano. PMID 33351586 DOI: 10.1021/acsnano.0c09206  0.807
2020 Mei KC, Liao YP, Jiang J, Chiang M, Khazaieli M, Liu X, Wang X, Liu Q, Chang CH, Zhang X, Li J, Ji Y, Melano B, Telesca D, Xia T, ... ... Nel AE, et al. Liposomal Delivery of Mitoxantrone and a Cholesteryl Indoximod Prodrug Provides Effective Chemo-Immunotherapy in Multiple Solid Tumors. Acs Nano. PMID 32940463 DOI: 10.1021/Acsnano.0C05194  0.799
2020 Wang X, Chang CH, Jiang J, Liu X, Li J, Liu Q, Liao YP, Li L, Nel AE, Xia T. Mechanistic Differences in Cell Death Responses to Metal-Based Engineered Nanomaterials in Kupffer Cells and Hepatocytes. Small (Weinheim An Der Bergstrasse, Germany). e2000528. PMID 32337854 DOI: 10.1002/Smll.202000528  0.806
2020 Wang X, Chang CH, Jiang J, Liu X, Li J, Liu Q, Liao Y, Li L, Nel AE, Xia T. Metal‐Based Nanoparticles: Mechanistic Differences in Cell Death Responses to Metal‐Based Engineered Nanomaterials in Kupffer Cells and Hepatocytes (Small 21/2020) Small. 16: 2070113. DOI: 10.1002/Smll.202070113  0.803
2019 Zhao Y, Bai C, Brinker CJ, Chi L, Dawson KA, Gogotsi Y, Halas NJ, Lee ST, Lee T, Liz-Marzán L, Miller JF, Mitra S, Nel AE, Nordlander P, Parak WJ, et al. Nano as a Rosetta Stone: The Global Roles and Opportunities for Nanoscience and Nanotechnology. Acs Nano. 13: 10853-10855. PMID 31683413 DOI: 10.1021/Acsnano.9B08042  0.426
2019 Wang X, Chang CH, Jiang J, Liu Q, Liao YP, Lu J, Li L, Liu X, Kim J, Ahmed A, Nel AE, Xia T. The Crystallinity and Aspect Ratio of Cellulose Nanomaterials Determine Their Pro-Inflammatory and Immune Adjuvant Effects In Vitro and In Vivo. Small (Weinheim An Der Bergstrasse, Germany). e1901642. PMID 31461215 DOI: 10.1002/Smll.201901642  0.805
2019 Leong HS, Butler KS, Brinker CJ, Azzawi M, Conlan S, Dufès C, Owen A, Rannard S, Scott C, Chen C, Dobrovolskaia MA, Kozlov SV, Prina-Mello A, Schmid R, Wick P, ... ... Nel A, et al. Publisher Correction: On the issue of transparency and reproducibility in nanomedicine. Nature Nanotechnology. PMID 31358944 DOI: 10.1038/S41565-019-0538-3  0.498
2019 Leong HS, Butler KS, Brinker CJ, Azzawi M, Conlan S, Dufès C, Owen A, Rannard S, Scott C, Chen C, Dobrovolskaia MA, Kozlov SV, Prina-Mello A, Schmid R, Wick P, ... ... Nel A, et al. Publisher Correction: On the issue of transparency and reproducibility in nanomedicine. Nature Nanotechnology. PMID 31289407 DOI: 10.1038/S41565-019-0523-X  0.498
2019 Leong HS, Butler KS, Brinker CJ, Azzawi M, Conlan S, Dufés C, Owen A, Rannard S, Scott C, Chen C, Dobrovolskaia MA, Kozlov SV, Prina-Mello A, Schmid R, Wick P, ... ... Nel A, et al. On the issue of transparency and reproducibility in nanomedicine. Nature Nanotechnology. 14: 629-635. PMID 31270452 DOI: 10.1038/S41565-019-0496-9  0.503
2019 Khademhosseini A, Nel AE, Bunje H, DeSantis CJ, Andrews AM, Blaik RA, Gu Z, Meng H, Ozcan A, Tolbert SH, Xia T, Zink JI, Weiss PS. Nanoscience and Nanotechnology at UCLA. Acs Nano. 13: 6127-6129. PMID 31247733 DOI: 10.1021/Acsnano.9B04680  0.74
2019 Liu Q, Wang X, Liu X, Kumar S, Gochman G, Ji Y, Liao YP, Chang CH, Situ W, Lu J, Jiang J, Mei KC, Meng H, Xia T, Nel AE. Use of Polymeric Nanoparticle Platform Targeting the Liver to Induce Treg-Mediated Antigen-Specific Immune Tolerance in a Pulmonary Allergen Sensitization Model. Acs Nano. PMID 30964276 DOI: 10.1021/Acsnano.9B01444  0.812
2018 Liu X, Jiang J, Chan R, Ji Y, Lu J, Liao YP, Okene M, Lin J, Lin P, Chang CH, Wang X, Tang I, Zheng E, Qiu W, Wainberg ZA, ... Nel AE, et al. Improved Efficacy and Reduced Toxicity Using a Custom-Designed Irinotecan-Delivering Silicasome for Orthotopic Colon Cancer. Acs Nano. PMID 30525443 DOI: 10.1021/Acsnano.8B06164  0.801
2018 Lu J, Liu X, Liao YP, Wang X, Ahmed A, Jiang W, Ji Y, Meng H, Nel AE. Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway. Acs Nano. 12: 11041-11061. PMID 30481959 DOI: 10.1021/acsnano.8b05189  0.801
2018 Meng H, Nel AE. Use of nano engineered approaches to overcome the stromal barrier in pancreatic cancer. Advanced Drug Delivery Reviews. PMID 29958925 DOI: 10.1016/J.Addr.2018.06.014  0.662
2018 Guiney LM, Wang X, Xia T, Nel AE, Hersam MC. Assessing and Mitigating the Hazard Potential of Two-Dimensional Materials. Acs Nano. PMID 29889491 DOI: 10.1021/Acsnano.8B02491  0.599
2018 Wang X, Lee JH, Li R, Liao YP, Kang J, Chang CH, Guiney LM, Mirshafiee V, Li L, Lu J, Xia T, Hersam MC, Nel AE. Toxicological Profiling of Highly Purified Single-Walled Carbon Nanotubes with Different Lengths in the Rodent Lung and Escherichia Coli. Small (Weinheim An Der Bergstrasse, Germany). e1703915. PMID 29733549 DOI: 10.1002/Smll.201703915  0.795
2018 Mirshafiee V, Sun B, Chang CH, Liao YP, Jiang W, Jiang J, Liu X, Wang X, Xia T, Nel AE. Toxicological Profiling of Metal Oxide Nanoparticles in Liver Context Reveals Pyroptosis in Kupffer Cells and Macrophages Versus Apoptosis in Hepatocytes. Acs Nano. PMID 29543433 DOI: 10.1021/Acsnano.8B01086  0.819
2018 Amorim MJB, Lin S, Schlich K, Navas JM, Brunelli A, Neubauer N, Vilsmeier K, Costa AL, Gondikas A, Xia T, Galbis L, Badetti E, Marcomini A, Hristozov D, Kammer FV, ... ... Nel A, et al. Environmental Impacts by Fragments Released from Nanoenabled Products: A Multiassay, Multimaterial Exploration by the SUN Approach. Environmental Science & Technology. PMID 29376638 DOI: 10.1021/Acs.Est.7B04122  0.726
2018 Li R, Guiney LM, Chang CH, Mansukhani ND, Ji Z, Wang X, Liao YP, Jiang W, Sun B, Hersam MC, Nel AE, Xia T. The Surface Oxidation of Graphene Oxide Determines Membrane Damage, Lipid Peroxidation, and Cytotoxicity in Macrophages in a Pulmonary Toxicity Model. Acs Nano. PMID 29328670 DOI: 10.1021/Acsnano.7B07737  0.811
2018 Nel A, Meng H. An engineered approach to pancreatic cancer using mesoporous silica nanocarriers and immune perturbation Nanomedicine: Nanotechnology, Biology and Medicine. 14: 1856-1857. DOI: 10.1016/J.Nano.2017.11.311  0.655
2017 Lu J, Liu X, Liao YP, Salazar F, Sun B, Jiang W, Chang CH, Jiang J, Wang X, Wu AM, Meng H, Nel AE. Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression. Nature Communications. 8: 1811. PMID 29180759 DOI: 10.1038/S41467-017-01651-9  0.809
2017 Nel A, Ruoslahti E, Meng H. New Insights into "Permeability" as in the Enhanced Permeability and Retention Effect of Cancer Nanotherapeutics. Acs Nano. 11: 9567-9569. PMID 29065443 DOI: 10.1021/Acsnano.7B07214  0.651
2017 Liu X, Jiang J, Nel AE, Meng H. Major effect of transcytosis on nano drug delivery to pancreatic cancer. Molecular & Cellular Oncology. 4: e1335273. PMID 28868347 DOI: 10.1080/23723556.2017.1335273  0.763
2017 Wang X, Liao YP, Telesca D, Chang CH, Xia T, Nel AE. The Genetic Heterogeneity among Different Mouse Strains Impacts the Lung Injury Potential of Multiwalled Carbon Nanotubes. Small (Weinheim An Der Bergstrasse, Germany). PMID 28677920 DOI: 10.1002/Smll.201700776  0.752
2017 Liu X, Lin P, Perrett I, Lin J, Liao YP, Chang CH, Jiang J, Wu N, Donahue T, Wainberg Z, Nel AE, Meng H. Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer. The Journal of Clinical Investigation. PMID 28414297 DOI: 10.1172/Jci92284  0.8
2017 Pelaz B, Alexiou C, Alvarez-Puebla RA, Alves F, Andrews AM, Ashraf S, Balogh LP, Ballerini L, Bestetti A, Brendel C, Bosi S, Carril M, Chan WC, Chen C, Chen X, ... ... Nel AE, et al. Diverse Applications of Nanomedicine. Acs Nano. PMID 28290206 DOI: 10.1021/Acsnano.6B06040  0.699
2017 Khademhosseini A, Chan WW, Chhowalla M, Glotzer SC, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kotov NA, Lee ST, Li Y, Möhwald H, Mulvaney PA, ... Nel AE, et al. Nanoscience and Nanotechnology Cross Borders. Acs Nano. PMID 28199099 DOI: 10.1021/Acsnano.7B00953  0.455
2017 Jiang W, Wang X, Osborne OJ, Du Y, Chang CH, Liao YP, Sun B, Jiang J, Ji Z, Li R, Liu X, Lu J, Lin S, Meng H, Xia T, ... Nel AE, et al. Pro-Inflammatory and Pro-Fibrogenic Effects of Ionic and Particulate Arsenide and Indium-Containing Semiconductor Materials in the Murine Lung. Acs Nano. PMID 28177603 DOI: 10.1021/Acsnano.6B07895  0.792
2017 Li Y, Wang J, Zhao F, Bai B, Nie G, Nel AE, Zhao Y. Nanomaterial libraries and model organisms for rapid high-content analysis of nanosafety National Science Review. 5: 365-388. DOI: 10.1093/Nsr/Nwx120  0.462
2017 Osborne OJ, Lin S, Jiang W, Chow J, Chang CH, Ji Z, Yu X, Lin S, Xia T, Nel AE. Differential effect of micron- versus nanoscale III–V particulates and ionic species on the zebrafish gut Environmental Science: Nano. 4: 1350-1364. DOI: 10.1039/C6En00675B  0.53
2016 Naatz H, Lin S, Li R, Jiang W, Ji Z, Chang CH, Koeser J, Thöming J, Xia T, Nel AE, Mädler L, Pokhrel S. Safe-by-Design of CuO Nanoparticles via Fe-Doping, Cu-O Bond Lengths Variation, and Biological Assessment in Cells and Zebrafish Embryos. Acs Nano. PMID 28026936 DOI: 10.1021/Acsnano.6B06495  0.79
2016 Li R, Mansukhani ND, Guiney LM, Ji Z, Zhao Y, Chang CH, French CT, Miller JF, Hersam MC, Nel AE, Xia T. Identification and Optimization of Carbon Radicals on Hydrated Graphene Oxide for Ubiquitous Antibacterial Coatings. Acs Nano. 10: 10966-10980. PMID 28024366 DOI: 10.1021/acsnano.6b05692  0.684
2016 Sisler JD, Li R, McKinney W, Mercer RR, Ji Z, Xia T, Wang X, Shaffer J, Orandle M, Mihalchik AL, Battelli L, Chen BT, Wolfarth M, Andrew ME, Schwegler-Berry D, ... ... Nel A, et al. Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during aerosolized inhalation in mice. Particle and Fibre Toxicology. 13: 42. PMID 27527840 DOI: 10.1186/S12989-016-0155-3  0.752
2016 Sun B, Wang X, Liao YP, Ji Z, Chang CH, Pokhrel S, Ku J, Liu X, Wang M, Dunphy DR, Li R, Meng H, Mädler L, Brinker CJ, Nel AE, et al. Repetitive Dosing of Fumed Silica Leads to Pro-Fibrogenic Effects Through Unique Structure-Activity Relationships and Biopersistence in the Lung. Acs Nano. PMID 27483033 DOI: 10.1021/Acsnano.6B04143  0.793
2016 Zhao H, Osborne OJ, Lin S, Ji Z, Damoiseux R, Wang Y, Nel AE, Lin S. Lanthanide Hydroxide Nanoparticles Induce Angiogenesis via ROS-Sensitive Signaling. Small (Weinheim An Der Bergstrasse, Germany). PMID 27383397 DOI: 10.1002/Smll.201600291  0.665
2016 Meng H, Wang M, Liu H, Liu X, Situ A, Wu B, Ji Z, Chang CH, Nel AE. Correction to Use of a Lipid-Coated Mesoporous Silica Nanoparticle Platform for Synergistic Gemcitabine and Paclitaxel Delivery to Human Pancreatic Cancer in Mice. Acs Nano. PMID 27199284 DOI: 10.1021/acsnano.6b03110  0.764
2016 Wang X, Mansukhani ND, Guiney LM, Lee JH, Li R, Sun B, Liao YP, Chang CH, Ji Z, Xia T, Hersam MC, Nel AE. Toxicological Profiling of Highly-Purified Metallic and Semiconducting Single-Walled Carbon Nanotubes in the Rodent Lung and E. coli. Acs Nano. PMID 27159184 DOI: 10.1021/Acsnano.6B01560  0.794
2016 Li N, Georas S, Alexis N, Fritz P, Xia T, Williams MA, Horner E, Nel A. A work group report on ultrafine particles (American Academy of Allergy, Asthma & Immunology): Why ambient ultrafine and engineered nanoparticles should receive special attention for possible adverse health outcomes in human subjects. The Journal of Allergy and Clinical Immunology. PMID 27130856 DOI: 10.1016/J.Jaci.2016.02.023  0.592
2016 Oh E, Liu R, Nel A, Gemill KB, Bilal M, Cohen Y, Medintz IL. Meta-analysis of cellular toxicity for cadmium-containing quantum dots. Nature Nanotechnology. PMID 26925827 DOI: 10.1038/Nnano.2015.338  0.303
2016 Liu X, Situ A, Kang Y, Villabroza KR, Liao YP, Chang CH, Donahue T, Nel AE, Meng H. Irinotecan Delivery by Lipid-Coated Mesoporous Silica Nanoparticles Show Improved Efficacy and Safety over Liposomes for Pancreatic Cancer. Acs Nano. PMID 26835979 DOI: 10.1021/Acsnano.5B07781  0.807
2015 Jiang W, Lin S, Chang CH, Ji Z, Sun B, Wang X, Li R, Pon N, Xia T, Nel AE. Implications of the Differential Toxicological Effects of III-V Ionic and Particulate Materials for Hazard Assessment of Semiconductor Slurries. Acs Nano. PMID 26549624 DOI: 10.1021/Acsnano.5B04847  0.799
2015 Osborne OJ, Lin S, Chang CH, Ji Z, Yu X, Wang X, Lin S, Xia T, Nel AE. Organ-Specific and Size-Dependent Ag Nanoparticle Toxicity in Gills and Intestines of Adult Zebrafish. Acs Nano. PMID 26327297 DOI: 10.1021/Acsnano.5B04583  0.736
2015 Liu R, Liu HH, Ji Z, Chang CH, Xia T, Nel AE, Cohen Y. Evaluation of Toxicity Ranking for Metal Oxide Nanoparticles via an in Vitro Dosimetry Model. Acs Nano. 9: 9303-13. PMID 26284985 DOI: 10.1021/Acsnano.5B04420  0.596
2015 Wang X, Mansukhani ND, Guiney LM, Ji Z, Chang CH, Wang M, Liao YP, Song TB, Sun B, Li R, Xia T, Hersam MC, Nel AE. Differences in the Toxicological Potential of 2D versus Aggregated Molybdenum Disulfide in the Lung. Small (Weinheim An Der Bergstrasse, Germany). PMID 26237579 DOI: 10.1002/Smll.201500906  0.803
2015 Sun B, Pokhrel S, Dunphy DR, Zhang H, Ji Z, Wang X, Wang M, Liao YP, Chang CH, Dong J, Li R, Mädler L, Brinker CJ, Nel AE, Xia T. Reduction of Acute Inflammatory Effects of Fumed Silica Nanoparticles in the Lung by Adjusting Silanol Display through Calcination and Metal Doping. Acs Nano. PMID 26200133 DOI: 10.1021/Acsnano.5B03443  0.809
2015 Kaweeteerawat C, Chang CH, Roy KR, Liu R, Li R, Toso D, Fischer H, Ivask A, Ji Z, Zink JI, Zhou ZH, Chanfreau GF, Telesca D, Cohen Y, Holden PA, ... Nel AE, et al. Cu Nanoparticles Have Different Impacts in Escherichia coli and Lactobacillus brevis than Their Microsized and Ionic Analogues. Acs Nano. 9: 7215-25. PMID 26168153 DOI: 10.1021/Acsnano.5B02021  0.582
2015 Nel AE, Parak WJ, Chan WC, Xia T, Hersam MC, Brinker CJ, Zink JI, Pinkerton KE, Baer DR, Weiss PS. Where Are We Heading in Nanotechnology Environmental Health and Safety and Materials Characterization? Acs Nano. 9: 5627-30. PMID 26100220 DOI: 10.1021/Acsnano.5B03496  0.591
2015 Zhang H, Wang X, Wang M, Li L, Chang CH, Ji Z, Xia T, Nel AE. Mammalian Cells Exhibit a Range of Sensitivities to Silver Nanoparticles that are Partially Explicable by Variations in Antioxidant Defense and Metallothionein Expression. Small (Weinheim An Der Bergstrasse, Germany). PMID 25930061 DOI: 10.1002/Smll.201500251  0.753
2015 Meng H, Wang M, Liu H, Liu X, Situ A, Wu B, Ji Z, Chang CH, Nel AE. Use of a lipid-coated mesoporous silica nanoparticle platform for synergistic gemcitabine and paclitaxel delivery to human pancreatic cancer in mice. Acs Nano. 9: 3540-57. PMID 25776964 DOI: 10.1021/Acsnano.5B00510  0.788
2015 Li R, Ji Z, Dong J, Chang CH, Wang X, Sun B, Wang M, Liao YP, Zink JI, Nel AE, Xia T. Enhancing the imaging and biosafety of upconversion nanoparticles through phosphonate coating. Acs Nano. 9: 3293-306. PMID 25727446 DOI: 10.1021/Acsnano.5B00439  0.813
2015 Wang X, Duch MC, Mansukhani N, Ji Z, Liao YP, Wang M, Zhang H, Sun B, Chang CH, Li R, Lin S, Meng H, Xia T, Hersam MC, Nel AE. Use of a pro-fibrogenic mechanism-based predictive toxicological approach for tiered testing and decision analysis of carbonaceous nanomaterials. Acs Nano. 9: 3032-43. PMID 25646681 DOI: 10.1021/Nn507243W  0.788
2015 Lin S, Taylor AA, Ji Z, Chang CH, Kinsinger NM, Ueng W, Walker SL, Nel AE. Understanding the transformation, speciation, and hazard potential of copper particles in a model septic tank system using zebrafish to monitor the effluent. Acs Nano. 9: 2038-48. PMID 25625504 DOI: 10.1021/Nn507216F  0.612
2015 Sun B, Wang X, Ji Z, Wang M, Liao YP, Chang CH, Li R, Zhang H, Nel AE, Xia T. NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes. Small (Weinheim An Der Bergstrasse, Germany). 11: 2087-97. PMID 25581126 DOI: 10.1002/Smll.201402859  0.806
2015 Kaweeteerawat C, Ivask A, Liu R, Zhang H, Chang CH, Low-Kam C, Fischer H, Ji Z, Pokhrel S, Cohen Y, Telesca D, Zink J, Mädler L, Holden PA, Nel A, et al. Toxicity of metal oxide nanoparticles in Escherichia coli correlates with conduction band and hydration energies. Environmental Science & Technology. 49: 1105-12. PMID 25563693 DOI: 10.1021/Es504259S  0.641
2015 Low-Kam C, Telesca D, Ji Z, Zhang H, Xia T, Zink JI, Nel AE. A bayesian regression tree approach to identify the effect of nanoparticles’ properties on toxicity profiles Annals of Applied Statistics. 9: 383-401. DOI: 10.1214/14-Aoas797  0.718
2015 Kaweeteerawat C, Chang CH, Roy KR, Liu R, Li R, Toso D, Fischer H, Ivask A, Ji Z, Zink JI, Zhou ZH, Chanfreau GF, Telesca D, Cohen Y, Holden PA, ... Nel AE, et al. Cu Nanoparticles Have Different Impacts in Escherichia coli and Lactobacillus brevis than Their Microsized and Ionic Analogues Acs Nano. 9: 7215-7225. DOI: 10.1021/acsnano.5b02021  0.567
2014 Li R, Ji Z, Qin H, Kang X, Sun B, Wang M, Chang CH, Wang X, Zhang H, Zou H, Nel AE, Xia T. Interference in autophagosome fusion by rare earth nanoparticles disrupts autophagic flux and regulation of an interleukin-1β producing inflammasome. Acs Nano. 8: 10280-92. PMID 25251502 DOI: 10.1021/Nn505002W  0.823
2014 Patel T, Telesca D, Low-Kam C, Ji Z, Zhang H, Xia T, Zinc JI, Nel AE. Relating Nanoparticle Properties to Biological Outcomes in Exposure Escalation Experiments. Environmetrics. 25: 57-68. PMID 24764692 DOI: 10.1002/Env.2246  0.603
2014 Lin S, Wang X, Ji Z, Chang CH, Dong Y, Meng H, Liao YP, Wang M, Song TB, Kohan S, Xia T, Zink JI, Lin S, Nel AE. Aspect ratio plays a role in the hazard potential of CeO2 nanoparticles in mouse lung and zebrafish gastrointestinal tract. Acs Nano. 8: 4450-64. PMID 24720650 DOI: 10.1021/Nn5012754  0.814
2014 Zhang H, Pokhrel S, Ji Z, Meng H, Wang X, Lin S, Chang CH, Li L, Li R, Sun B, Wang M, Liao YP, Liu R, Xia T, Mädler L, ... Nel AE, et al. PdO doping tunes band-gap energy levels as well as oxidative stress responses to a Co₃O₄ p-type semiconductor in cells and the lung. Journal of the American Chemical Society. 136: 6406-20. PMID 24673286 DOI: 10.1021/Ja501699E  0.807
2014 Li R, Ji Z, Chang CH, Dunphy DR, Cai X, Meng H, Zhang H, Sun B, Wang X, Dong J, Lin S, Wang M, Liao YP, Brinker CJ, Nel A, et al. Surface interactions with compartmentalized cellular phosphates explain rare earth oxide nanoparticle hazard and provide opportunities for safer design. Acs Nano. 8: 1771-83. PMID 24417322 DOI: 10.1021/Nn406166N  0.817
2014 Heber D, Li Z, Garcia-Lloret M, Wong AM, Lee TY, Thames G, Krak M, Zhang Y, Nel A. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Food & Function. 5: 35-41. PMID 24287881 DOI: 10.1039/C3Fo60277J  0.323
2014 Liu R, France B, George S, Rallo R, Zhang H, Xia T, Nel AE, Bradley K, Cohen Y. Association rule mining of cellular responses induced by metal and metal oxide nanoparticles. The Analyst. 139: 943-53. PMID 24260774 DOI: 10.1039/C3An01409F  0.798
2014 Wang X, Ji Z, Chang CH, Zhang H, Wang M, Liao YP, Lin S, Meng H, Li R, Sun B, Winkle LV, Pinkerton KE, Zink JI, Xia T, Nel AE. Use of coated silver nanoparticles to understand the relationship of particle dissolution and bioavailability to cell and lung toxicological potential. Small (Weinheim An Der Bergstrasse, Germany). 10: 385-98. PMID 24039004 DOI: 10.1002/Smll.201301597  0.805
2014 Lu B, Smith T, Li R, Xia T, Nel A, Schmidt J. Nanoparticle-Membrane Interactions Studied with Lipid Bilayer Arrays Biophysical Journal. 106: 415a. DOI: 10.1016/J.Bpj.2013.11.2336  0.716
2013 Patel T, Telesca D, Rallo R, George S, Xia T, Nel AE. Hierarchical Rank Aggregation with Applications to Nanotoxicology. Journal of Agricultural, Biological, and Environmental Statistics. 18: 159-177. PMID 24839387 DOI: 10.1007/S13253-013-0129-Y  0.722
2013 Sun B, Ji Z, Liao YP, Wang M, Wang X, Dong J, Chang CH, Li R, Zhang H, Nel AE, Xia T. Engineering an effective immune adjuvant by designed control of shape and crystallinity of aluminum oxyhydroxide nanoparticles. Acs Nano. 7: 10834-49. PMID 24261790 DOI: 10.1021/Nn404211J  0.804
2013 Meng H, Zhao Y, Dong J, Xue M, Lin YS, Ji Z, Mai WX, Zhang H, Chang CH, Brinker CJ, Zink JI, Nel AE. Two-wave nanotherapy to target the stroma and optimize gemcitabine delivery to a human pancreatic cancer model in mice. Acs Nano. 7: 10048-65. PMID 24143858 DOI: 10.1021/Nn404083M  0.765
2013 Nel A, Zhao Y, Mädler L. Environmental health and safety considerations for nanotechnology. Accounts of Chemical Research. 46: 605-6. PMID 23964654 DOI: 10.1021/Ar400005V  0.407
2013 Nel AE, Nasser E, Godwin H, Avery D, Bahadori T, Bergeson L, Beryt E, Bonner JC, Boverhof D, Carter J, Castranova V, Deshazo JR, Hussain SM, Kane AB, Klaessig F, et al. A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment. Acs Nano. 7: 6422-33. PMID 23924032 DOI: 10.1021/Nn4037927  0.31
2013 Jiang S, Cheng R, Wang X, Xue T, Liu Y, Nel A, Huang Y, Duan X. Real-time electrical detection of nitric oxide in biological systems with sub-nanomolar sensitivity. Nature Communications. 4: 2225. PMID 23887829 DOI: 10.1038/Ncomms3225  0.369
2013 Liu R, Zhang HY, Ji ZX, Rallo R, Xia T, Chang CH, Nel A, Cohen Y. Development of structure-activity relationship for metal oxide nanoparticles. Nanoscale. 5: 5644-53. PMID 23689214 DOI: 10.1039/C3Nr01533E  0.606
2013 Zhao Y, Nel A, Riehemann K. Filling knowledge gaps that distinguish the safety profiles of nano versus bulk materials. Small. 9: 1426-1427. PMID 23681784 DOI: 10.1002/Smll.201300500  0.425
2013 Xia T, Hamilton RF, Bonner JC, Crandall ED, Elder A, Fazlollahi F, Girtsman TA, Kim K, Mitra S, Ntim SA, Orr G, Tagmount M, Taylor AJ, Telesca D, Tolic A, ... ... Nel A, et al. Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environmental Health Perspectives. 121: 683-90. PMID 23649538 DOI: 10.1289/Ehp.1306561  0.65
2013 Li N, Wang M, Barajas B, Sioutas C, Williams MA, Nel AE. Nrf2 deficiency in dendritic cells enhances the adjuvant effect of ambient ultrafine particles on allergic sensitization. Journal of Innate Immunity. 5: 543-54. PMID 23595026 DOI: 10.1159/000347060  0.327
2013 Li R, Wang X, Ji Z, Sun B, Zhang H, Chang CH, Lin S, Meng H, Liao YP, Wang M, Li Z, Hwang AA, Song TB, Xu R, Yang Y, ... ... Nel AE, et al. Surface charge and cellular processing of covalently functionalized multiwall carbon nanotubes determine pulmonary toxicity. Acs Nano. 7: 2352-68. PMID 23414138 DOI: 10.1021/Nn305567S  0.796
2013 Meng H, Mai WX, Zhang H, Xue M, Xia T, Lin S, Wang X, Zhao Y, Ji Z, Zink JI, Nel AE. Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo. Acs Nano. 7: 994-1005. PMID 23289892 DOI: 10.1021/Nn3044066  0.797
2013 Lin S, Zhao Y, Nel AE, Lin S. Zebrafish: an in vivo model for nano EHS studies. Small (Weinheim An Der Bergstrasse, Germany). 9: 1608-18. PMID 23208995 DOI: 10.1002/Smll.201202115  0.664
2013 Pokhrel S, Nel AE, Mädler L. Custom-designed nanomaterial libraries for testing metal oxide toxicity. Accounts of Chemical Research. 46: 632-41. PMID 23194152 DOI: 10.1021/Ar300032Q  0.363
2013 Lin S, Zhao Y, Ji Z, Ear J, Chang CH, Zhang H, Low-Kam C, Yamada K, Meng H, Wang X, Liu R, Pokhrel S, Mädler L, Damoiseaux R, Xia T, ... ... Nel AE, et al. Zebrafish high-throughput screening to study the impact of dissolvable metal oxide nanoparticles on the hatching enzyme, ZHE1. Small (Weinheim An Der Bergstrasse, Germany). 9: 1776-85. PMID 23180726 DOI: 10.1002/Smll.201202128  0.811
2013 Xia T, Malasarn D, Lin S, Ji Z, Zhang H, Miller RJ, Keller AA, Nisbet RM, Harthorn BH, Godwin HA, Lenihan HS, Liu R, Gardea-Torresdey J, Cohen Y, Mädler L, ... ... Nel AE, et al. Implementation of a multidisciplinary approach to solve complex nano EHS problems by the UC Center for the Environmental Implications of Nanotechnology. Small (Weinheim An Der Bergstrasse, Germany). 9: 1428-43. PMID 23027589 DOI: 10.1002/Smll.201201700  0.768
2013 Zhu M, Nie G, Meng H, Xia T, Nel A, Zhao Y. Physicochemical properties determine nanomaterial cellular uptake, transport, and fate. Accounts of Chemical Research. 46: 622-31. PMID 22891796 DOI: 10.1021/Ar300031Y  0.776
2013 Nel A, Xia T, Meng H, Wang X, Lin S, Ji Z, Zhang H. Nanomaterial toxicity testing in the 21st century: use of a predictive toxicological approach and high-throughput screening. Accounts of Chemical Research. 46: 607-21. PMID 22676423 DOI: 10.1021/Ar300022H  0.798
2013 Lin S, Zhao Y, Ji Z, Ear J, Chang CH, Zhang H, Low-Kam C, Yamada K, Meng H, Wang X, Liu R, Pokhrel S, Mädler L, Damoiseaux R, Xia T, ... ... Nel AE, et al. Metal Oxides: Zebrafish High-Throughput Screening to Study the Impact of Dissolvable Metal Oxide Nanoparticles on the Hatching Enzyme, ZHE1 (Small 9-10/2013) Small. 9: 1775-1775. DOI: 10.1002/Smll.201370059  0.787
2012 Meng H, Xue M, Zink JI, Nel AE. Development of Pharmaceutically Adapted Mesoporous Silica Nanoparticles Platform. The Journal of Physical Chemistry Letters. 3: 358-9. PMID 26285851 DOI: 10.1021/Jz300021X  0.693
2012 Patel T, Telesca D, George S, Nel AE. TOXICITY PROFILING OF ENGINEERED NANOMATERIALS VIA MULTIVARIATE DOSE-RESPONSE SURFACE MODELING. The Annals of Applied Statistics. 6: 1707-1729. PMID 25191531 DOI: 10.1214/12-Aoas563  0.658
2012 Zhang H, Dunphy DR, Jiang X, Meng H, Sun B, Tarn D, Xue M, Wang X, Lin S, Ji Z, Li R, Garcia FL, Yang J, Kirk ML, Xia T, ... ... Nel A, et al. Processing pathway dependence of amorphous silica nanoparticle toxicity: colloidal vs pyrolytic. Journal of the American Chemical Society. 134: 15790-804. PMID 22924492 DOI: 10.1021/Ja304907C  0.81
2012 Zamboni WC, Torchilin V, Patri AK, Hrkach J, Stern S, Lee R, Nel A, Panaro NJ, Grodzinski P. Best practices in cancer nanotechnology: perspective from NCI nanotechnology alliance. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3229-41. PMID 22669131 DOI: 10.1158/1078-0432.Ccr-11-2938  0.358
2012 Gilbert B, Fakra SC, Xia T, Pokhrel S, Mädler L, Nel AE. The fate of ZnO nanoparticles administered to human bronchial epithelial cells. Acs Nano. 6: 4921-30. PMID 22646753 DOI: 10.1021/Nn300425A  0.635
2012 Ji Z, Wang X, Zhang H, Lin S, Meng H, Sun B, George S, Xia T, Nel AE, Zink JI. Designed synthesis of CeO2 nanorods and nanowires for studying toxicological effects of high aspect ratio nanomaterials. Acs Nano. 6: 5366-80. PMID 22564147 DOI: 10.1021/Nn3012114  0.797
2012 Wang X, Xia T, Duch MC, Ji Z, Zhang H, Li R, Sun B, Lin S, Meng H, Liao YP, Wang M, Song TB, Yang Y, Hersam MC, Nel AE. Pluronic F108 coating decreases the lung fibrosis potential of multiwall carbon nanotubes by reducing lysosomal injury. Nano Letters. 12: 3050-61. PMID 22546002 DOI: 10.1021/Nl300895Y  0.784
2012 Liu R, Lin S, Rallo R, Zhao Y, Damoiseaux R, Xia T, Lin S, Nel A, Cohen Y. Automated phenotype recognition for zebrafish embryo based in vivo high throughput toxicity screening of engineered nano-materials. Plos One. 7: e35014. PMID 22506062 DOI: 10.1371/Journal.Pone.0035014  0.699
2012 Zhang H, Ji Z, Xia T, Meng H, Low-Kam C, Liu R, Pokhrel S, Lin S, Wang X, Liao YP, Wang M, Li L, Rallo R, Damoiseaux R, Telesca D, ... ... Nel AE, et al. Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation. Acs Nano. 6: 4349-68. PMID 22502734 DOI: 10.1021/Nn3010087  0.801
2012 George S, Lin S, Ji Z, Thomas CR, Li L, Mecklenburg M, Meng H, Wang X, Zhang H, Xia T, Hohman JN, Lin S, Zink JI, Weiss PS, Nel AE. Surface defects on plate-shaped silver nanoparticles contribute to its hazard potential in a fish gill cell line and zebrafish embryos. Acs Nano. 6: 3745-59. PMID 22482460 DOI: 10.1021/Nn204671V  0.804
2012 Clemens DL, Lee BY, Xue M, Thomas CR, Meng H, Ferris D, Nel AE, Zink JI, Horwitz MA. Targeted intracellular delivery of antituberculosis drugs to Mycobacterium tuberculosis-infected macrophages via functionalized mesoporous silica nanoparticles. Antimicrobial Agents and Chemotherapy. 56: 2535-45. PMID 22354311 DOI: 10.1128/Aac.06049-11  0.687
2012 Meng H, Xue M, Zink JI, Nel AE. Development of pharmaceutically adapted mesoporous silica nanoparticles platform Journal of Physical Chemistry Letters. 3: 358-359. DOI: 10.1021/jz300021x  0.667
2011 Wang X, Xia T, Ntim SA, Ji Z, Lin S, Meng H, Chung CH, George S, Zhang H, Wang M, Li N, Yang Y, Castranova V, Mitra S, Bonner JC, ... Nel AE, et al. Dispersal state of multiwalled carbon nanotubes elicits profibrogenic cellular responses that correlate with fibrogenesis biomarkers and fibrosis in the murine lung. Acs Nano. 5: 9772-87. PMID 22047207 DOI: 10.1021/Nn2033055  0.797
2011 Lin S, Zhao Y, Xia T, Meng H, Ji Z, Liu R, George S, Xiong S, Wang X, Zhang H, Pokhrel S, Mädler L, Damoiseaux R, Lin S, Nel AE. High content screening in zebrafish speeds up hazard ranking of transition metal oxide nanoparticles. Acs Nano. 5: 7284-95. PMID 21851096 DOI: 10.1021/Nn202116P  0.791
2011 George S, Pokhrel S, Ji Z, Henderson BL, Xia T, Li L, Zink JI, Nel AE, Mädler L. Role of Fe doping in tuning the band gap of TiO2 for the photo-oxidation-induced cytotoxicity paradigm. Journal of the American Chemical Society. 133: 11270-8. PMID 21678906 DOI: 10.1021/Ja202836S  0.742
2011 Li N, Nel AE. Feasibility of biomarker studies for engineered nanoparticles: what can be learned from air pollution research. Journal of Occupational and Environmental Medicine. 53: S74-9. PMID 21654422 DOI: 10.1097/Jom.0B013E31821B1Bf2  0.341
2011 Meng H, Yang S, Li Z, Xia T, Chen J, Ji Z, Zhang H, Wang X, Lin S, Huang C, Zhou ZH, Zink JI, Nel AE. Aspect ratio determines the quantity of mesoporous silica nanoparticle uptake by a small GTPase-dependent macropinocytosis mechanism. Acs Nano. 5: 4434-47. PMID 21563770 DOI: 10.1021/Nn103344K  0.803
2011 Meng H, Xue M, Xia T, Ji Z, Tarn DY, Zink JI, Nel AE. Use of size and a copolymer design feature to improve the biodistribution and the enhanced permeability and retention effect of doxorubicin-loaded mesoporous silica nanoparticles in a murine xenograft tumor model. Acs Nano. 5: 4131-44. PMID 21524062 DOI: 10.1021/Nn200809T  0.775
2011 Liu R, Rallo R, George S, Ji Z, Nair S, Nel AE, Cohen Y. Classification NanoSAR development for cytotoxicity of metal oxide nanoparticles. Small (Weinheim An Der Bergstrasse, Germany). 7: 1118-26. PMID 21456088 DOI: 10.1002/Smll.201002366  0.685
2011 Zhang H, Xia T, Meng H, Xue M, George S, Ji Z, Wang X, Liu R, Wang M, France B, Rallo R, Damoiseaux R, Cohen Y, Bradley KA, Zink JI, ... Nel AE, et al. Differential expression of syndecan-1 mediates cationic nanoparticle toxicity in undifferentiated versus differentiated normal human bronchial epithelial cells. Acs Nano. 5: 2756-69. PMID 21366263 DOI: 10.1021/Nn200328M  0.807
2011 George S, Xia T, Rallo R, Zhao Y, Ji Z, Lin S, Wang X, Zhang H, France B, Schoenfeld D, Damoiseaux R, Liu R, Lin S, Bradley KA, Cohen Y, ... Nel AE, et al. Use of a high-throughput screening approach coupled with in vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials. Acs Nano. 5: 1805-17. PMID 21323332 DOI: 10.1021/Nn102734S  0.801
2011 Damoiseaux R, George S, Li M, Pokhrel S, Ji Z, France B, Xia T, Suarez E, Rallo R, Mädler L, Cohen Y, Hoek EM, Nel A. No time to lose--high throughput screening to assess nanomaterial safety. Nanoscale. 3: 1345-60. PMID 21301704 DOI: 10.1039/C0Nr00618A  0.718
2011 Thomas CR, George S, Horst AM, Ji Z, Miller RJ, Peralta-Videa JR, Xia T, Pokhrel S, Mädler L, Gardea-Torresdey JL, Holden PA, Keller AA, Lenihan HS, Nel AE, Zink JI. Nanomaterials in the environment: from materials to high-throughput screening to organisms. Acs Nano. 5: 13-20. PMID 21261306 DOI: 10.1021/Nn1034857  0.735
2011 Rallo R, France B, Liu R, Nair S, George S, Damoiseaux R, Giralt F, Nel A, Bradley K, Cohen Y. Self-organizing map analysis of toxicity-related cell signaling pathways for metal and metal oxide nanoparticles. Environmental Science & Technology. 45: 1695-702. PMID 21250674 DOI: 10.1021/Es103606X  0.679
2011 Xia T, Zhao Y, Sager T, George S, Pokhrel S, Li N, Schoenfeld D, Meng H, Lin S, Wang X, Wang M, Ji Z, Zink JI, Mädler L, Castranova V, ... ... Nel AE, et al. Decreased dissolution of ZnO by iron doping yields nanoparticles with reduced toxicity in the rodent lung and zebrafish embryos. Acs Nano. 5: 1223-35. PMID 21250651 DOI: 10.1021/Nn1028482  0.802
2011 Roebben G, Ramirez-Garcia S, Hackley VA, Roesslein M, Klaessig F, Kestens V, Lynch I, Garner CM, Rawle A, Elder A, Colvin VL, Kreyling W, Krug HF, Lewicka ZA, McNeil S, ... Nel A, et al. Interlaboratory comparison of size and surface charge measurements on nanoparticles prior to biological impact assessment Journal of Nanoparticle Research. 13: 2675-2687. DOI: 10.1007/S11051-011-0423-Y  0.608
2010 Wang X, Xia T, Ntim SA, Ji Z, George S, Meng H, Zhang H, Castranova V, Mitra S, Nel AE. Quantitative techniques for assessing and controlling the dispersion and biological effects of multiwalled carbon nanotubes in mammalian tissue culture cells. Acs Nano. 4: 7241-52. PMID 21067152 DOI: 10.1021/Nn102112B  0.791
2010 Meng H, Liong M, Xia T, Li Z, Ji Z, Zink JI, Nel AE. Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and P-glycoprotein siRNA to overcome drug resistance in a cancer cell line. Acs Nano. 4: 4539-50. PMID 20731437 DOI: 10.1021/Nn100690M  0.758
2010 Meng H, Xue M, Xia T, Zhao YL, Tamanoi F, Stoddart JF, Zink JI, Nel AE. Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles by pH-sensitive nanovalves. Journal of the American Chemical Society. 132: 12690-7. PMID 20718462 DOI: 10.1021/Ja104501A  0.772
2010 Li N, Harkema JR, Lewandowski RP, Wang M, Bramble LA, Gookin GR, Ning Z, Kleinman MT, Sioutas C, Nel AE. Ambient ultrafine particles provide a strong adjuvant effect in the secondary immune response: implication for traffic-related asthma flares. American Journal of Physiology. Lung Cellular and Molecular Physiology. 299: L374-83. PMID 20562226 DOI: 10.1152/Ajplung.00115.2010  0.31
2010 Ji Z, Jin X, George S, Xia T, Meng H, Wang X, Suarez E, Zhang H, Hoek EM, Godwin H, Nel AE, Zink JI. Dispersion and stability optimization of TiO2 nanoparticles in cell culture media. Environmental Science & Technology. 44: 7309-14. PMID 20536146 DOI: 10.1021/Es100417S  0.81
2010 George S, Pokhrel S, Xia T, Gilbert B, Ji Z, Schowalter M, Rosenauer A, Damoiseaux R, Bradley KA, Mädler L, Nel AE. Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping. Acs Nano. 4: 15-29. PMID 20043640 DOI: 10.1021/Nn901503Q  0.77
2009 Meng H, Xia T, George S, Nel AE. A predictive toxicological paradigm for the safety assessment of nanomaterials. Acs Nano. 3: 1620-7. PMID 21452863 DOI: 10.1021/Nn9005973  0.783
2009 Klichko Y, Liong M, Choi E, Angelos S, Nel AE, Stoddart JF, Tamanoi F, Zink JI. Mesostructured Silica for Optical Functionality, Nanomachines, and Drug Delivery. Journal of the American Ceramic Society. American Ceramic Society. 92: s2-s10. PMID 19834571 DOI: 10.1111/J.1551-2916.2008.02722.X  0.381
2009 Araujo JA, Nel AE. Particulate matter and atherosclerosis: role of particle size, composition and oxidative stress. Particle and Fibre Toxicology. 6: 24. PMID 19761620 DOI: 10.1186/1743-8977-6-24  0.302
2009 Kovochich M, Espinasse B, Auffan M, Hotze EM, Wessel L, Xia T, Nel AE, Wiesner MR. Comparative toxicity of C60 aggregates toward mammalian cells: role of tetrahydrofuran (THF) decomposition. Environmental Science & Technology. 43: 6378-84. PMID 19746740 DOI: 10.1021/Es900990D  0.61
2009 Xia T, Kovochich M, Liong M, Meng H, Kabehie S, George S, Zink JI, Nel AE. Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs. Acs Nano. 3: 3273-86. PMID 19739605 DOI: 10.1021/Nn900918W  0.811
2009 Xia T, Li N, Nel AE. Potential health impact of nanoparticles. Annual Review of Public Health. 30: 137-50. PMID 19705557 DOI: 10.1146/Annurev.Publhealth.031308.100155  0.584
2009 Li N, Wang M, Bramble LA, Schmitz DA, Schauer JJ, Sioutas C, Harkema JR, Nel AE. The adjuvant effect of ambient particulate matter is closely reflected by the particulate oxidant potential. Environmental Health Perspectives. 117: 1116-23. PMID 19654922 DOI: 10.1289/Ehp.0800319  0.328
2009 Nel AE, Mädler L, Velegol D, Xia T, Hoek EM, Somasundaran P, Klaessig F, Castranova V, Thompson M. Understanding biophysicochemical interactions at the nano-bio interface. Nature Materials. 8: 543-57. PMID 19525947 DOI: 10.1038/Nmat2442  0.605
2009 Meng H, Xia T, George S, Nel AE. Reply to “Assessing the Safety of Nanomaterials by Genomic Approach Could Be Another Alternative” Acs Nano. 3: 3830-3831. DOI: 10.1021/Nn901576J  0.759
2009 Pokhrel S, Xia T, Kovochich M, Liong M, Schowalter M, Rosenauer A, Gilbert B, Zink J, Nel A, Mädler L. Comparison of the mechanism of toxicity of binary and mixed binary metal oxide nanoparticles based on dissolution and oxidative stress properties Chemie Ingenieur Technik. 81: 1167-1167. DOI: 10.1002/Cite.200950629  0.588
2008 Xia T, Kovochich M, Liong M, Zink JI, Nel AE. Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways. Acs Nano. 2: 85-96. PMID 19206551 DOI: 10.1021/Nn700256C  0.605
2008 Liong M, Lu J, Kovochich M, Xia T, Ruehm SG, Nel AE, Tamanoi F, Zink JI. Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery. Acs Nano. 2: 889-96. PMID 19206485 DOI: 10.1021/Nn800072T  0.616
2008 Xia T, Kovochich M, Liong M, Mädler L, Gilbert B, Shi H, Yeh JI, Zink JI, Nel AE. Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. Acs Nano. 2: 2121-34. PMID 19206459 DOI: 10.1021/Nn800511K  0.638
2008 Xia T, Rome L, Nel A. Nanobiology: particles slip cell security. Nature Materials. 7: 519-20. PMID 18574478 DOI: 10.1038/Nmat2213  0.591
2008 Li N, Xia T, Nel AE. The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. Free Radical Biology & Medicine. 44: 1689-99. PMID 18313407 DOI: 10.1016/J.Freeradbiomed.2008.01.028  0.609
2008 Ayres JG, Borm P, Cassee FR, Castranova V, Donaldson K, Ghio A, Harrison RM, Hider R, Kelly F, Kooter IM, Marano F, Maynard RL, Mudway I, Nel A, Sioutas C, et al. Evaluating the toxicity of airborne particulate matter and nanoparticles by measuring oxidative stress potential--a workshop report and consensus statement. Inhalation Toxicology. 20: 75-99. PMID 18236225 DOI: 10.1080/08958370701665517  0.552
2007 Lu J, Liong M, Sherman S, Xia T, Kovochich M, Nel AE, Zink JI, Tamanoi F. Mesoporous Silica Nanoparticles for Cancer Therapy: Energy-Dependent Cellular Uptake and Delivery of Paclitaxel to Cancer Cells. Nanobiotechnology : the Journal At the Intersection of Nanotechnology, Molecular Biology, and Biomedical Sciences. 3: 89-95. PMID 19936038 DOI: 10.1007/S12030-008-9003-3  0.627
2007 Shi H, Xia T, Nel AE, Yeh JI. Part II: coordinated biosensors--development of enhanced nanobiosensors for biological and medical applications. Nanomedicine (London, England). 2: 599-614. PMID 17976023 DOI: 10.2217/17435889.2.5.599  0.538
2007 Jung EJ, Avliyakulov NK, Boontheung P, Loo JA, Nel AE. Pro-oxidative DEP chemicals induce heat shock proteins and an unfolding protein response in a bronchial epithelial cell line as determined by DIGE analysis. Proteomics. 7: 3906-18. PMID 17922515 DOI: 10.1002/Pmic.200700377  0.322
2007 Kim HJ, Barajas B, Chan RC, Nel AE. Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: implications for systemic disease and immunosenescence. The Journal of Allergy and Clinical Immunology. 119: 1225-33. PMID 17335885 DOI: 10.1016/J.Jaci.2007.01.016  0.304
2007 Xia T, Kovochich M, Nel AE. Impairment of mitochondrial function by particulate matter (PM) and their toxic components: implications for PM-induced cardiovascular and lung disease. Frontiers in Bioscience : a Journal and Virtual Library. 12: 1238-46. PMID 17127377 DOI: 10.2741/2142  0.559
2006 Xia T, Kovochich M, Nel A. The role of reactive oxygen species and oxidative stress in mediating particulate matter injury. Clinics in Occupational and Environmental Medicine. 5: 817-36. PMID 17110294 DOI: 10.1016/J.Coem.2006.07.005  0.557
2006 Xia T, Kovochich M, Brant J, Hotze M, Sempf J, Oberley T, Sioutas C, Yeh JI, Wiesner MR, Nel AE. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Letters. 6: 1794-807. PMID 16895376 DOI: 10.1021/Nl061025K  0.635
2006 Chan RC, Wang M, Li N, Yanagawa Y, Onoé K, Lee JJ, Nel AE. Pro-oxidative diesel exhaust particle chemicals inhibit LPS-induced dendritic cell responses involved in T-helper differentiation. The Journal of Allergy and Clinical Immunology. 118: 455-65. PMID 16890772 DOI: 10.1016/J.Jaci.2006.06.006  0.319
2006 Li N, Nel AE. The cellular impacts of diesel exhaust particles: beyond inflammation and death. The European Respiratory Journal. 27: 667-8. PMID 16585072 DOI: 10.1183/09031936.06.00025006  0.335
2006 Nel A, Xia T, Mädler L, Li N. Toxic potential of materials at the nanolevel. Science (New York, N.Y.). 311: 622-7. PMID 16456071 DOI: 10.1126/Science.1114397  0.574
2005 Kim HJ, Nel AE. The role of phase II antioxidant enzymes in protecting memory T cells from spontaneous apoptosis in young and old mice. Journal of Immunology (Baltimore, Md. : 1950). 175: 2948-59. PMID 16116181 DOI: 10.4049/Jimmunol.175.5.2948  0.303
2005 Wang M, Xiao GG, Li N, Xie Y, Loo JA, Nel AE. Use of a fluorescent phosphoprotein dye to characterize oxidative stress-induced signaling pathway components in macrophage and epithelial cultures exposed to diesel exhaust particle chemicals. Electrophoresis. 26: 2092-108. PMID 15880549 DOI: 10.1002/Elps.200410428  0.312
2004 Xia T, Korge P, Weiss JN, Li N, Venkatesen MI, Sioutas C, Nel A. Quinones and aromatic chemical compounds in particulate matter induce mitochondrial dysfunction: implications for ultrafine particle toxicity. Environmental Health Perspectives. 112: 1347-58. PMID 15471724 DOI: 10.1289/Ehp.7167  0.566
2004 Li N, Alam J, Venkatesan MI, Eiguren-Fernandez A, Schmitz D, Di Stefano E, Slaughter N, Killeen E, Wang X, Huang A, Wang M, Miguel AH, Cho A, Sioutas C, Nel AE. Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals. Journal of Immunology (Baltimore, Md. : 1950). 173: 3467-81. PMID 15322212 DOI: 10.4049/Jimmunol.173.5.3467  0.404
2003 Xiao GG, Wang M, Li N, Loo JA, Nel AE. Use of proteomics to demonstrate a hierarchical oxidative stress response to diesel exhaust particle chemicals in a macrophage cell line. The Journal of Biological Chemistry. 278: 50781-90. PMID 14522998 DOI: 10.1074/Jbc.M306423200  0.326
2003 Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, Wang M, Oberley T, Froines J, Nel A. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environmental Health Perspectives. 111: 455-60. PMID 12676598 DOI: 10.1289/Ehp.6000  0.328
2002 Li N, Wang M, Oberley TD, Sempf JM, Nel AE. Comparison of the pro-oxidative and proinflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages. Journal of Immunology (Baltimore, Md. : 1950). 169: 4531-41. PMID 12370390 DOI: 10.4049/Jimmunol.169.8.4531  0.366
2002 Li N, Kim S, Wang M, Froines J, Sioutas C, Nel A. Use of a stratified oxidative stress model to study the biological effects of ambient concentrated and diesel exhaust particulate matter. Inhalation Toxicology. 14: 459-86. PMID 12028803 DOI: 10.1080/089583701753678571  0.307
2002 Whitekus MJ, Li N, Zhang M, Wang M, Horwitz MA, Nelson SK, Horwitz LD, Brechun N, Diaz-Sanchez D, Nel AE. Thiol antioxidants inhibit the adjuvant effects of aerosolized diesel exhaust particles in a murine model for ovalbumin sensitization. Journal of Immunology (Baltimore, Md. : 1950). 168: 2560-7. PMID 11859152 DOI: 10.4049/Jimmunol.168.5.2560  0.344
2001 Laux I, Nel A. Evidence that oxidative stress-induced apoptosis by menadione involves Fas-dependent and Fas-independent pathways. Clinical Immunology. 101: 335-344. PMID 11726226 DOI: 10.1006/Clim.2001.5129  0.319
2001 Nel AE, Diaz-Sanchez D, Li N. The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress. Current Opinion in Pulmonary Medicine. 7: 20-6. PMID 11140402 DOI: 10.1097/00063198-200101000-00004  0.33
2000 Diaz-Sanchez D, Jyrala M, Ng D, Nel A, Saxon A. In Vivo Nasal Challenge with Diesel Exhaust Particles Enhances Expression of the CC Chemokines Rantes, MIP-1α, and MCP-3 in Humans Clinical Immunology. 97: 140-145. PMID 11027454 DOI: 10.1006/Clim.2000.4921  0.342
2000 Li N, Venkatesan MI, Miguel A, Kaplan R, Gujuluva C, Alam J, Nel A. Induction of Heme Oxygenase-1 Expression in Macrophages by Diesel Exhaust Particle Chemicals and Quinones via the Antioxidant-Responsive Element Journal of Immunology. 165: 3393-3401. PMID 10975858 DOI: 10.4049/Jimmunol.165.6.3393  0.326
2000 Casillas AM, Hiura T, Li N, Nel AE. Enhancement of allergic inflammation by diesel exhaust particles: permissive role of reactive oxygen species. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. 83: 624-9. PMID 10619333 DOI: 10.1016/S1081-1206(10)62884-0  0.345
1998 Nel AE, Diaz-Sanchez D, Ng D, Hiura T, Saxon A. Enhancement of allergic inflammation by the interaction between diesel exhaust particles and the immune system. The Journal of Allergy and Clinical Immunology. 102: 539-54. PMID 9802360 DOI: 10.1016/S0091-6749(98)70269-6  0.318
1997 Faris M, Kokot N, Stahl N, Nel AE. Involvement of Stat3 in interleukin-6-induced IgM production in a human B-cell line. Immunology. 90: 350-7. PMID 9155640 DOI: 10.1111/J.1365-2567.1997.00350.X  0.301
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