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Aseem Z. Ansari, PhD - Publications

Affiliations: 
Biochemistry University of Wisconsin, Madison, Madison, WI 
Area:
Regulation of gene expression at the interface of chemistry, biology and genomics
Website:
http://www.biochem.wisc.edu/faculty/ansari/default.aspx
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88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mohammed A, Waddell MB, Sutkeviciute I, Danda A, Philips SJ, Lang W, Slavish PJ, Kietlinska SJ, Kaulage M, Sourav D, Ansari AZ. Domain-Selective BET Ligands Yield Next-Generation Synthetic Genome Readers/Regulators with Nonidentical Cellular Functions. Journal of the American Chemical Society. PMID 37923569 DOI: 10.1021/jacs.3c06297  0.364
2023 Bhimsaria D, Rodríguez-Martínez JA, Mendez-Johnson JL, Ghoshdastidar D, Varadarajan A, Bansal M, Daniels DL, Ramanathan P, Ansari AZ. Hidden modes of DNA binding by human nuclear receptors. Nature Communications. 14: 4179. PMID 37443151 DOI: 10.1038/s41467-023-39577-0  0.438
2022 Matos-Rodrigues G, van Wietmarschen N, Wu W, Tripathi V, Koussa NC, Pavani R, Nathan WJ, Callen E, Belinky F, Mohammed A, Napierala M, Usdin K, Ansari AZ, Mirkin SM, Nussenzweig A. S1-END-seq reveals DNA secondary structures in human cells. Molecular Cell. PMID 36075220 DOI: 10.1016/j.molcel.2022.08.007  0.395
2020 Finn PB, Bhimsaria D, Ali A, Eguchi A, Ansari AZ, Dervan PB. Single position substitution of hairpin pyrrole-imidazole polyamides imparts distinct DNA-binding profiles across the human genome. Plos One. 15: e0243905. PMID 33351840 DOI: 10.1371/journal.pone.0243905  0.51
2019 Liu X, Gupta STP, Bhimsaria D, Reed JL, Rodríguez-Martínez JA, Ansari AZ, Raman S. De novo design of programmable inducible promoters. Nucleic Acids Research. PMID 31552424 DOI: 10.1093/Nar/Gkz772  0.782
2019 Ansari AZ. A chemoprobe tracks its target. The Journal of Biological Chemistry. 294: 8323-8324. PMID 31101661 DOI: 10.1074/Jbc.H119.008945  0.327
2018 Nemec CM, Singh AK, Ali A, Tseng SC, Syal K, Ringelberg KJ, Ho YH, Hintermair C, Ahmad MF, Kar RK, Gasch AP, Akhtar MS, Eick D, Ansari AZ. Noncanonical CTD kinases regulate RNA polymerase II in a gene-class-specific manner. Nature Chemical Biology. PMID 30598543 DOI: 10.1038/S41589-018-0194-1  0.37
2018 Yella VR, Bhimsaria D, Ghoshdastidar D, Rodríguez-Martínez JA, Ansari AZ, Bansal M. Flexibility and structure of flanking DNA impact transcription factor affinity for its core motif. Nucleic Acids Research. PMID 30395339 DOI: 10.1093/Nar/Gky1057  0.837
2018 Bhimsaria D, Rodríguez-Martínez JA, Pan J, Roston D, Korkmaz EN, Cui Q, Ramanathan P, Ansari AZ. Specificity landscapes unmask submaximal binding site preferences of transcription factors. Proceedings of the National Academy of Sciences of the United States of America. PMID 30341220 DOI: 10.1073/Pnas.1811431115  0.829
2018 Cho E, Mysliwiec MR, Carlson CD, Ansari AZ, Schwartz RJ, Lee Y. Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development. The Journal of Biological Chemistry. PMID 29891551 DOI: 10.1074/Jbc.Ra118.002482  0.647
2018 Heiderscheit EA, Eguchi A, Spurgat MC, Ansari AZ. Reprogramming cell fate with artificial transcription factors. Febs Letters. PMID 29389011 DOI: 10.1002/1873-3468.12993  0.454
2017 Erwin GS, Grieshop MP, Ali A, Qi J, Lawlor M, Kumar D, Ahmad I, McNally A, Teider N, Worringer K, Sivasankaran R, Syed DN, Eguchi A, Ashraf M, Jeffery J, ... ... Ansari AZ, et al. Synthetic transcription elongation factors license transcription across repressive chromatin. Science (New York, N.Y.). PMID 29192133 DOI: 10.1126/Science.Aan6414  0.834
2017 Nemec CM, Yang F, Gilmore JM, Hintermair C, Ho YH, Tseng SC, Heidemann M, Zhang Y, Florens L, Gasch AP, Eick D, Washburn MP, Varani G, Ansari AZ. Different phosphoisoforms of RNA polymerase II engage the Rtt103 termination factor in a structurally analogous manner. Proceedings of the National Academy of Sciences of the United States of America. PMID 28465432 DOI: 10.1073/Pnas.1700128114  0.431
2017 Rodriguez-Martinez JA, Reinke AW, Bhimsaria D, Keating AE, Ansari AZ. Combinatorial bZIP dimers define complex DNA-binding specificity landscapes. Elife. 6. PMID 28186491 DOI: 10.7554/Elife.19272  0.831
2017 Rodríguez-Martínez JA, Reinke AW, Bhimsaria D, Keating AE, Ansari AZ. Author response: Combinatorial bZIP dimers display complex DNA-binding specificity landscapes Elife. DOI: 10.7554/Elife.19272.031  0.809
2016 Eguchi A, Wleklinski MJ, Spurgat MC, Heiderscheit EA, Kropornicka AS, Vu CK, Bhimsaria D, Swanson SA, Stewart R, Ramanathan P, Kamp TJ, Slukvin I, Thomson JA, Dutton JR, Ansari AZ. Reprogramming cell fate with a genome-scale library of artificial transcription factors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27930301 DOI: 10.1073/Pnas.1611142114  0.499
2016 Erwin GS, Grieshop MP, Bhimsaria D, Do TJ, Rodríguez-Martínez JA, Mehta C, Khanna K, Swanson SA, Stewart R, Thomson JA, Ramanathan P, Ansari AZ. Synthetic genome readers target clustered binding sites across diverse chromatin states. Proceedings of the National Academy of Sciences of the United States of America. PMID 27830652 DOI: 10.1073/Pnas.1604847113  0.83
2016 Xiong K, Erwin GS, Ansari AZ, Blainey PC. Sliding on DNA: From Peptides to Small Molecules. Angewandte Chemie (International Ed. in English). PMID 27813331 DOI: 10.1002/Anie.201606768  0.83
2016 Rodríguez-Molina JB, Tseng SC, Simonett SP, Taunton J, Ansari AZ. Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization. Molecular Cell. PMID 27477907 DOI: 10.1016/J.Molcel.2016.06.036  0.362
2016 Erwin GS, Grieshop MP, Bhimsaria D, Eguchi A, Rodríguez-Martínez JA, Ansari AZ. Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin). Journal of Visualized Experiments : Jove. PMID 26863565 DOI: 10.3791/53510  0.834
2014 Eguchi A, Lee GO, Wan F, Erwin GS, Ansari AZ. Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers. The Biochemical Journal. 462: 397-413. PMID 25145439 DOI: 10.1042/Bj20140400  0.838
2014 Erwin GS, Bhimsaria D, Eguchi A, Ansari AZ. Mapping polyamide-DNA interactions in human cells reveals a new design strategy for effective targeting of genomic sites. Angewandte Chemie (International Ed. in English). 53: 10124-8. PMID 25066383 DOI: 10.1002/Anie.201405497  0.833
2013 Park DM, Akhtar MS, Ansari AZ, Landick R, Kiley PJ. The Bacterial Response Regulator ArcA Uses a Diverse Binding Site Architecture to Regulate Carbon Oxidation Globally Plos Genetics. 9. PMID 24146625 DOI: 10.1371/Journal.Pgen.1003839  0.478
2012 Tan-Wong SM, Zaugg JB, Camblong J, Xu Z, Zhang DW, Mischo HE, Ansari AZ, Luscombe NM, Steinmetz LM, Proudfoot NJ. Gene loops enhance transcriptional directionality. Science (New York, N.Y.). 338: 671-5. PMID 23019609 DOI: 10.1126/Science.1224350  0.404
2012 Campbell ZT, Bhimsaria D, Valley CT, Rodriguez-Martinez JA, Menichelli E, Williamson JR, Ansari AZ, Wickens M. Cooperativity in RNA-protein interactions: global analysis of RNA binding specificity. Cell Reports. 1: 570-81. PMID 22708079 DOI: 10.1016/J.Celrep.2012.04.003  0.784
2012 Zhang DW, Rodríguez-Molina JB, Tietjen JR, Nemec CM, Ansari AZ. Emerging Views on the CTD Code. Genetics Research International. 2012: 347214. PMID 22567385 DOI: 10.1155/2012/347214  0.793
2012 Chinchilla K, Rodriguez-Molina JB, Ursic D, Finkel JS, Ansari AZ, Culbertson MR. Interactions of Sen1, Nrd1, and Nab3 with multiple phosphorylated forms of the Rpb1 C-terminal domain in Saccharomyces cerevisiae. Eukaryotic Cell. 11: 417-29. PMID 22286094 DOI: 10.1128/Ec.05320-11  0.42
2012 Zhang DW, Mosley AL, Ramisetty SR, Rodríguez-Molina JB, Washburn MP, Ansari AZ. Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination Journal of Biological Chemistry. 287: 8541-8551. PMID 22235117 DOI: 10.1074/Jbc.M111.335687  0.371
2012 Warren CL, Zhao J, Glass K, Rishi V, Ansari AZ, Vinson C. Fabrication of duplex DNA microarrays incorporating methyl-5-cytosine Lab On a Chip - Miniaturisation For Chemistry and Biology. 12: 376-380. PMID 22139143 DOI: 10.1039/C1Lc20698B  0.464
2012 Mysliwiec MR, Carlson CD, Tietjen J, Hung H, Ansari AZ, Lee Y. Jarid2 (Jumonji, AT rich interactive domain 2) regulates NOTCH1 expression via histone modification in the developing heart Journal of Biological Chemistry. 287: 1235-1241. PMID 22110129 DOI: 10.1074/Jbc.M111.315945  0.775
2011 Ansari AZ, Peterson-Kaufman KJ. A partner evokes latent differences between Hox proteins. Cell. 147: 1220-1. PMID 22153067 DOI: 10.1016/J.Cell.2011.11.046  0.53
2011 Davis SE, Mooney RA, Kanin EI, Grass J, Landick R, Ansari AZ. Mapping E. coli RNA polymerase and associated transcription factors and identifying promoters genome-wide. Methods in Enzymology. 498: 449-71. PMID 21601690 DOI: 10.1016/B978-0-12-385120-8.00020-6  0.566
2011 Tietjen JR, Donato LJ, Bhimisaria D, Ansari AZ. Sequence-specificity and energy landscapes of DNA-binding molecules Methods in Enzymology. 497: 3-30. PMID 21601080 DOI: 10.1016/B978-0-12-385075-1.00001-9  0.849
2010 Peterson-Kaufman KJ, Carlson CD, Rodríguez-Martínez JA, Ansari AZ. Nucleating the assembly of macromolecular complexes. Chembiochem : a European Journal of Chemical Biology. 11: 1955-62. PMID 20812316 DOI: 10.1002/Cbic.201000255  0.802
2010 Rodríguez-Martínez JA, Peterson-Kaufman KJ, Ansari AZ. Small-molecule regulators that mimic transcription factors. Biochimica Et Biophysica Acta. 1799: 768-74. PMID 20804876 DOI: 10.1016/J.Bbagrm.2010.08.010  0.782
2010 Tietjen JR, Zhang DW, Rodríguez-Molina JB, White BE, Akhtar MS, Heidemann M, Li X, Chapman RD, Shokat K, Keles S, Eick D, Ansari AZ. Chemical-genomic dissection of the CTD code Nature Structural and Molecular Biology. 17: 1154-1161. PMID 20802488 DOI: 10.1038/Nsmb.1900  0.79
2010 Müller P, Park S, Shor E, Huebert DJ, Warren CL, Ansari AZ, Weinreich M, Eaton ML, MacAlpine DM, Fox CA. The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin Genes and Development. 24: 1418-1433. PMID 20595233 DOI: 10.1101/Gad.1906410  0.488
2010 Carlson CD, Warren CL, Hauschild KE, Ozers MS, Qadir N, Bhimsaria D, Lee Y, Cerrina F, Ansari AZ. Specificity landscapes of DNA binding molecules elucidate biological function Proceedings of the National Academy of Sciences of the United States of America. 107: 4544-4549. PMID 20176964 DOI: 10.1073/Pnas.0914023107  0.843
2009 Shor E, Warren CL, Tietjen J, Hou Z, Müller U, Alborelli I, Gohard FH, Yemm AI, Borisov L, Broach JR, Weinreich M, Nieduszynski CA, Ansari AZ, Fox CA. The origin recognition complex interacts with a subset of metabolic genes tightly linked to origins of replication Plos Genetics. 5. PMID 19997491 DOI: 10.1371/Journal.Pgen.1000755  0.81
2009 Arora PS, Ansari AZ. Chemical biology: A Notch above other inhibitors. Nature. 462: 171-3. PMID 19907487 DOI: 10.1038/462171A  0.406
2009 Ozers MS, Warren CL, Ansari AZ. Determining DNA sequence specificity of natural and artificial transcription factors by cognate site identifier analysis. Methods in Molecular Biology (Clifton, N.J.). 544: 637-653. PMID 19488729 DOI: 10.1007/978-1-59745-483-4_41  0.564
2009 Ozers MS, Warren CL, Ansari AZ. Determining DNA sequence specificity of natural and artificial transcription factors by cognate site identifier analysis. Methods in Molecular Biology (Clifton, N.J.). 544: 637-653. PMID 19488729 DOI: 10.1007/978-1-59745-483-4_41  0.564
2009 Stanton BC, Giles SS, Kruzel EK, Warren CL, Ansari AZ, Hull CM. Cognate Site Identifier analysis reveals novel binding properties of the Sex Inducer homeodomain proteins of Cryptococcus neoformans. Molecular Microbiology. 72: 1334-47. PMID 19486297 DOI: 10.1111/J.1365-2958.2009.06719.X  0.377
2009 Stanton BC, Giles SS, Kruzel EK, Warren CL, Ansari AZ, Hull CM. Cognate Site Identifier analysis reveals novel binding properties of the Sex Inducer homeodomain proteins of Cryptococcus neoformans. Molecular Microbiology. 72: 1334-47. PMID 19486297 DOI: 10.1111/J.1365-2958.2009.06719.X  0.377
2009 Akhtar MS, Heidemann M, Tietjen JR, Zhang DW, Chapman RD, Eick D, Ansari AZ. TFIIH Kinase Places Bivalent Marks on the Carboxy-Terminal Domain of RNA Polymerase II Molecular Cell. 34: 387-393. PMID 19450536 DOI: 10.1016/J.Molcel.2009.04.016  0.781
2009 Hauschild KE, Stover JS, Boger DL, Ansari AZ. CSI-FID: high throughput label-free detection of DNA binding molecules. Bioorganic & Medicinal Chemistry Letters. 19: 3779-82. PMID 19435662 DOI: 10.1016/J.Bmcl.2009.04.097  0.839
2009 Hauschild KE, Stover JS, Boger DL, Ansari AZ. CSI-FID: high throughput label-free detection of DNA binding molecules. Bioorganic & Medicinal Chemistry Letters. 19: 3779-82. PMID 19435662 DOI: 10.1016/J.Bmcl.2009.04.097  0.839
2009 Ansari AZ. Riboactivators: Transcription activation by noncoding RNA riboactivators: Transcription activation by noncoding RNA A. Z. Ansari Critical Reviews in Biochemistry and Molecular Biology. 44: 50-61. PMID 19280431 DOI: 10.1080/10409230902734044  0.4
2009 Mooney RA, Davis SE, Peters JM, Rowland JL, Ansari AZ, Landick R. Regulator trafficking on bacterial transcription units in vivo. Molecular Cell. 33: 97-108. PMID 19150431 DOI: 10.1016/J.Molcel.2008.12.021  0.3
2009 Mooney RA, Davis SE, Peters JM, Rowland JL, Ansari AZ, Landick R. Regulator trafficking on bacterial transcription units in vivo. Molecular Cell. 33: 97-108. PMID 19150431 DOI: 10.1016/J.Molcel.2008.12.021  0.3
2008 Badis G, Chan ET, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson CD, Gossett AJ, Hasinoff MJ, Warren CL, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, ... ... Ansari AZ, et al. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular Cell. 32: 878-87. PMID 19111667 DOI: 10.1016/J.Molcel.2008.11.020  0.8
2008 Badis G, Chan ET, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson CD, Gossett AJ, Hasinoff MJ, Warren CL, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, ... ... Ansari AZ, et al. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular Cell. 32: 878-87. PMID 19111667 DOI: 10.1016/J.Molcel.2008.11.020  0.8
2008 Moretti R, Donato LJ, Brezinski ML, Stafford RL, Hoff H, Thorson JS, Dervan PB, Ansari AZ. Targeted chemical wedges reveal the role of allosteric DNA modulation in protein-DNA assembly. Acs Chemical Biology. 3: 220-9. PMID 18422304 DOI: 10.1021/Cb700258R  0.73
2008 Keleş S, Warren CL, Carlson CD, Ansari AZ. CSI-Tree: a regression tree approach for modeling binding properties of DNA-binding molecules based on cognate site identification (CSI) data. Nucleic Acids Research. 36: 3171-84. PMID 18411210 DOI: 10.1093/Nar/Gkn057  0.785
2008 Moretti R, Ansari AZ. Expanding the specificity of DNA targeting by harnessing cooperative assembly. Biochimie. 90: 1015-25. PMID 18343232 DOI: 10.1016/J.Biochi.2008.02.014  0.714
2007 Puckett JW, Muzikar KA, Tietjen J, Warren CL, Ansari AZ, Dervan PB. Quantitative microarray profiling of DNA-binding molecules. Journal of the American Chemical Society. 129: 12310-9. PMID 17880081 DOI: 10.1021/Ja0744899  0.819
2007 Kanin EI, Kipp RT, Kung C, Slattery M, Viale A, Hahn S, Shokat KM, Ansari AZ. Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 5812-7. PMID 17392431 DOI: 10.1073/Pnas.0611505104  0.403
2007 Stafford RL, Arndt HD, Brezinski ML, Ansari AZ, Dervan PB. Minimization of a protein-DNA dimerizer. Journal of the American Chemical Society. 129: 2660-8. PMID 17290996 DOI: 10.1021/Ja067971K  0.476
2007 Mapp AK, Ansari AZ. A TAD further: exogenous control of gene activation. Acs Chemical Biology. 2: 62-75. PMID 17243784 DOI: 10.1021/Cb600463W  0.41
2006 Lum JK, Majmudar CY, Ansari AZ, Mapp AK. Converting inactive peptides into potent transcriptional activators. Acs Chemical Biology. 1: 639-43. PMID 17175579 DOI: 10.1021/Cb600363N  0.428
2006 Steinmetz EJ, Warren CL, Kuehner JN, Panbehi B, Ansari AZ, Brow DA. Genome-wide distribution of yeast RNA polymerase II and its control by Sen1 helicase. Molecular Cell. 24: 735-46. PMID 17157256 DOI: 10.1016/J.Molcel.2006.10.023  0.377
2006 Warren CL, Kratochvil NC, Hauschild KE, Foister S, Brezinski ML, Dervan PB, Phillips GN, Ansari AZ. Defining the sequence-recognition profile of DNA-binding molecules. Proceedings of the National Academy of Sciences of the United States of America. 103: 867-72. PMID 16418267 DOI: 10.1073/Pnas.0509843102  0.845
2005 Raffaelle M, Kanin EI, Vogt J, Burgess RR, Ansari AZ. Holoenzyme switching and stochastic release of sigma factors from RNA polymerase in vivo. Molecular Cell. 20: 357-66. PMID 16285918 DOI: 10.1016/J.Molcel.2005.10.011  0.385
2005 Herring CD, Raffaelle M, Allen TE, Kanin EI, Landick R, Ansari AZ, Palsson BØ. Immobilization of Escherichia coli RNA polymerase and location of binding sites by use of chromatin immunoprecipitation and microarrays. Journal of Bacteriology. 187: 6166-74. PMID 16109958 DOI: 10.1128/Jb.187.17.6166-6174.2005  0.537
2005 Lu Z, Rowe SP, Brennan BB, Davis SE, Metzler RE, Nau JJ, Majmudar CY, Mapp AK, Ansari AZ. Unraveling the mechanism of a potent transcriptional activator. The Journal of Biological Chemistry. 280: 29689-98. PMID 15886204 DOI: 10.1074/Jbc.M504895200  0.497
2005 Hauschild KE, Metzler RE, Arndt HD, Moretti R, Raffaelle M, Dervan PB, Ansari AZ. Temperature-sensitive protein-DNA dimerizers. Proceedings of the National Academy of Sciences of the United States of America. 102: 5008-13. PMID 15781856 DOI: 10.1073/Pnas.0501289102  0.837
2005 Ansari AZ, Ogirala A, Ptashne M. Transcriptional activating regions target attached substrates to a cyclin-dependent kinase. Proceedings of the National Academy of Sciences of the United States of America. 102: 2346-9. PMID 15687503 DOI: 10.1073/Pnas.0409671102  0.59
2004 Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell. 14: 553-7. PMID 15175151 DOI: 10.1016/J.Molcel.2004.05.011  0.593
2004 Liu Y, Kung C, Fishburn J, Ansari AZ, Shokat KM, Hahn S. Two cyclin-dependent kinases promote RNA polymerase II transcription and formation of the scaffold complex. Molecular and Cellular Biology. 24: 1721-35. PMID 14749387 DOI: 10.1128/Mcb.24.4.1721-1735.2004  0.371
2003 Arndt HD, Hauschild KE, Sullivan DP, Lake K, Dervan PB, Ansari AZ. Toward artificial developmental regulators. Journal of the American Chemical Society. 125: 13322-3. PMID 14583004 DOI: 10.1021/Ja0371395  0.831
2003 Ansari AZ. Fingers reach for the genome. Nature Biotechnology. 21: 242-3. PMID 12610568 DOI: 10.1038/Nbt0303-242  0.306
2003 Saha S, Ansari AZ, Jarrell KA, Ptashne M, Jarell KA. RNA sequences that work as transcriptional activating regions. Nucleic Acids Research. 31: 1565-70. PMID 12595565 DOI: 10.1093/Nar/Gkg227  0.609
2002 Ansari AZ, Mapp AK. Modular design of artificial transcription factors. Current Opinion in Chemical Biology. 6: 765-72. PMID 12470729 DOI: 10.1016/S1367-5931(02)00377-0  0.414
2002 Ansari AZ, Koh SS, Zaman Z, Bongards C, Lehming N, Young RA, Ptashne M. Transcriptional activating regions target a cyclin-dependent kinase. Proceedings of the National Academy of Sciences of the United States of America. 99: 14706-9. PMID 12417740 DOI: 10.1073/Pnas.232573899  0.577
2002 Arora PS, Ansari AZ, Best TP, Ptashne M, Dervan PB. Design of artificial transcriptional activators with rigid poly-L-proline linkers. Journal of the American Chemical Society. 124: 13067-71. PMID 12405833 DOI: 10.1021/Ja0208355  0.684
2002 Lu Z, Ansari AZ, Lu X, Ogirala A, Ptashne M. A target essential for the activity of a nonacidic yeast transcriptional activator. Proceedings of the National Academy of Sciences of the United States of America. 99: 8591-6. PMID 12084920 DOI: 10.1073/Pnas.092263499  0.626
2001 Ansari AZ, Mapp AK, Nguyen DH, Dervan PB, Ptashne M. Towards a minimal motif for artificial transcriptional activators. Chemistry & Biology. 8: 583-92. PMID 11410377 DOI: 10.1016/S1074-5521(01)00037-0  0.674
2001 Hidalgo P, Ansari AZ, Schmidt P, Hare B, Simkovich N, Farrell S, Shin EJ, Ptashne M, Wagner G. Recruitment of the transcriptional machinery through GAL11P: structure and interactions of the GAL4 dimerization domain. Genes & Development. 15: 1007-20. PMID 11316794 DOI: 10.1101/Gad.873901  0.659
2001 Zaman Z, Ansari AZ, Koh SS, Young R, Ptashne M. Interaction of a transcriptional repressor with the RNA polymerase II holoenzyme plays a crucial role in repression. Proceedings of the National Academy of Sciences of the United States of America. 98: 2550-4. PMID 11226276 DOI: 10.1073/Pnas.041611198  0.62
2000 Mapp AK, Ansari AZ, Ptashne M, Dervan PB. Activation of gene expression by small molecule transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 97: 3930-5. PMID 10760265 DOI: 10.1073/Pnas.97.8.3930  0.739
2000 Lu X, Ansari AZ, Ptashne M. An artificial transcriptional activating region with unusual properties. Proceedings of the National Academy of Sciences of the United States of America. 97: 1988-92. PMID 10681438 DOI: 10.1073/Pnas.040573197  0.616
1998 Zaman Z, Ansari AZ, Gaudreau L, Nevado J, Ptashne M. Gene transcription by recruitment. Cold Spring Harbor Symposia On Quantitative Biology. 63: 167-71. PMID 10384280 DOI: 10.1101/Sqb.1998.63.167  0.578
1998 Ansari AZ, Reece RJ, Ptashne M. A transcriptional activating region with two contrasting modes of protein interaction. Proceedings of the National Academy of Sciences of the United States of America. 95: 13543-8. PMID 9811836 DOI: 10.1073/Pnas.95.23.13543  0.668
1998 Koh SS, Ansari AZ, Ptashne M, Young RA. An activator target in the RNA polymerase II holoenzyme. Molecular Cell. 1: 895-904. PMID 9660972 DOI: 10.1016/S1097-2765(00)80088-X  0.64
1995 Ansari AZ, Bradner JE, O'Halloran TV. DNA-bend modulation in a repressor-to-activator switching mechanism. Nature. 374: 371-5. PMID 7885478 DOI: 10.1038/374370A0  0.688
1993 Parkhill J, Ansari AZ, Wright JG, Brown NL, O'Halloran TV. Construction and characterization of a mercury-independent MerR activator (MerRAC): transcriptional activation in the absence of Hg(II) is accompanied by DNA distortion. The Embo Journal. 12: 413-21. PMID 8440234 DOI: 10.1002/J.1460-2075.1993.Tb05673.X  0.681
1992 Ansari AZ, Chael ML, O'Halloran TV. Allosteric underwinding of DNA is a critical step in positive control of transcription by Hg-MerR. Nature. 355: 87-9. PMID 1731201 DOI: 10.1038/355087A0  0.713
1991 Parkhill J, Ansari AZ, Wright JG, O'Halloran TV, Brown N. Induction of the mer operon of Tn501 by the MerR repressor/activator. Journal of Inorganic Biochemistry. 43: 520. DOI: 10.1016/0162-0134(91)84497-W  0.527
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