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Brian S. Cummings - Publications

Affiliations: 
Pharmaceutical and Biomedical Sciences University of Georgia, Athens, Athens, GA, United States 
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53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Mitra Ghosh T, White J, Davis J, Mazumder S, Kansom T, Skarupa E, Barnett GS, Piazza GA, Bird RC, Mitra AK, Yates C, Cummings BS, Arnold RD. Identification and Characterization of Key Differentially Expressed Genes Associated With Metronomic Dosing of Topotecan in Human Prostate Cancer. Frontiers in Pharmacology. 12: 736951. PMID 34938177 DOI: 10.3389/fphar.2021.736951  0.562
2021 Kaur SP, Verma A, Lee HK, Barnett LM, Somanath PR, Cummings BS. Inhibition of glypican-1 expression induces an activated fibroblast phenotype in a human bone marrow-derived stromal cell-line. Scientific Reports. 11: 9262. PMID 33927256 DOI: 10.1038/s41598-021-88519-7  0.328
2020 Najahi-Missaoui W, Arnold RD, Cummings BS. Safe Nanoparticles: Are We There Yet? International Journal of Molecular Sciences. 22. PMID 33396561 DOI: 10.3390/ijms22010385  0.456
2020 Najahi-Missaoui W, Quach ND, Somanath PR, Cummings BS. Liposomes Targeting P21 Activated Kinase-1 (PAK-1) and Selective for Secretory Phospholipase A (sPLA) Decrease Cell Viability and Induce Apoptosis in Metastatic Triple-Negative Breast Cancer Cells. International Journal of Molecular Sciences. 21. PMID 33321758 DOI: 10.3390/ijms21249396  0.312
2020 Verma A, Najahi-Missaoui W, Cummings BS, Somanath PR. Sterically stabilized liposomes targeting P21 (RAC1) activated kinase-1 and secreted phospholipase A suppress prostate cancer growth and metastasis. Oncology Letters. 20: 179. PMID 32934746 DOI: 10.3892/Ol.2020.12040  0.402
2020 Verma A, Artham S, Alwhaibi A, Adil MS, Cummings BS, Somanath PR. PAK1 inhibitor IPA-3 mitigates metastatic prostate cancer-induced bone remodeling. Biochemical Pharmacology. 177: 113943. PMID 32240651 DOI: 10.1016/J.Bcp.2020.113943  0.346
2020 Finnerty MC, Ingram LM, Mansoura M, Cummings BS. Lipidomic Analysis Demonstrates that 36:1 Phosphatidylcholine is Enriched in Cell Models of Drug Resistance Prostate Cancer The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03279  0.394
2020 Alnaim AS, Arnold R, Eggert M, Nie B, Jasper S, Davis J, Panizzi P, Cummings B, Quach N. Role of PLA2R1 and sPLA2 on Drug Release and Uptake of Liposome Nanoparticles in Prostate Cancer The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03071  0.584
2019 Najahi-Missaoui W, Quach ND, Jenkins A, Dabke I, Somanath PR, Cummings BS. Effect of P21-activated kinase 1 (PAK-1) inhibition on cancer cell growth, migration, and invasion. Pharmacology Research & Perspectives. 7: e00518. PMID 31516713 DOI: 10.1002/Prp2.518  0.42
2019 Quach ND, Kaur SP, Eggert MW, Ingram L, Ghosh D, Sheth S, Nagy T, Dawson MR, Arnold RD, Cummings BS. Paradoxical Role of Glypican-1 in Prostate Cancer Cell and Tumor Growth. Scientific Reports. 9: 11478. PMID 31391540 DOI: 10.1038/S41598-019-47874-2  0.611
2019 Kaur SP, Cummings BS. Role of Glypicans in Regulation of the Tumor Microenvironment and Cancer Progression. Biochemical Pharmacology. PMID 31251939 DOI: 10.1016/J.Bcp.2019.06.020  0.385
2019 Barnett LMA, Cummings BS. Cellular and Molecular Mechanisms of Kidney Toxicity. Seminars in Nephrology. 39: 141-151. PMID 30827337 DOI: 10.1016/J.Semnephrol.2018.12.004  0.303
2019 Ghosh TM, Mitra AK, Davis J, Cummings B, Yates C, Arnold R. Abstract LB-267: Transcriptomic and epigenomic analysis of metastatic castration-resistant prostate cancer and a pan-cancer analysis of its genetic signatures Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-Lb-267  0.359
2019 Alnaim AS, Eggert MW, Nie B, Quanch ND, Jasper SL, Davis J, Barnett GS, Cummings BS, Panizzi PR, Arnold RD. Abstract 2985: Identifying uptake and biodistribution of liposome nanoparticles associated with secretes phospholipase A2proteins and PLA2receptors within a prostate cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2985  0.578
2019 Ghosh TM, Davis J, Barnett GS, Skarupa E, Warner JD, Cummings BS, Arnold RD. Abstract 2944: Identification of key transcriptomic and epigenomic factors influencing conventional and metronomic dosing in aggressive and non-aggressive prostate cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2944  0.567
2019 Kaur SP, Lee HK, Arnold RD, Cummings BS. Abstract 1913: Role of glypican 1 in regulating fibroblast activation in the prostate cancer tumor microenvironment Cancer Research. 79: 1913-1913. DOI: 10.1158/1538-7445.Sabcs18-1913  0.617
2019 Jasper SL, Skarupa EB, Cummings BS, Arnold RD. Abstract 991: Secretory phospholipase A2 as a trigger for drug release in the treatment of triple-negative breast cancer Cancer Research. 79: 991-991. DOI: 10.1158/1538-7445.Am2019-991  0.567
2019 Şahin N, Şahin-Bölükbaşı S, Tahir MN, Arıcı C, Çevik E, Gürbüz N, Özdemir İ, Cummings BS. Synthesis, characterization and anticancer activity of allyl substituted N-Heterocyclic carbene silver(I) complexes Journal of Molecular Structure. 1179: 92-99. DOI: 10.1016/J.Molstruc.2018.10.094  0.34
2019 Şahin-Bölükbaşı S, Şahin N, Tahir MN, Arıcı C, Çevik E, Gürbüz N, Özdemir İ, Cummings BS. Novel N-heterocyclic carbene silver(I) complexes: Synthesis, structural characterization, and anticancer activity Inorganica Chimica Acta. 486: 711-718. DOI: 10.1016/J.Ica.2018.11.044  0.311
2018 Missaoui WN, Arnold RD, Cummings BS. Toxicological Status of Nanoparticles: What We Know and What We Don't Know. Chemico-Biological Interactions. PMID 30048623 DOI: 10.1016/J.Cbi.2018.07.015  0.511
2017 Quach ND, Eggert M, Ghosh D, Dawson MR, Arnold R, Cummings BS. Abstract 4465: Glypican-1: A tumor suppressor or an oncogene in human bone metastatic prostate cancer cells Cancer Research. 77: 4465-4465. DOI: 10.1158/1538-7445.Am2017-4465  0.571
2016 Scholpa NE, Kolli RT, Moore M, Arnold RD, Glenn TC, Cummings BS. Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer. Chemico-Biological Interactions. PMID 27543423 DOI: 10.1016/J.Cbi.2016.08.010  0.593
2016 Al-Azayzih A, Missaoui WN, Cummings BS, Somanath PR. Liposomal-mediated delivery of the p21 activated kinase-1 (PAK-1) inhibitor IPA-3 limits prostate tumor growth in vivo. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 26949163 DOI: 10.1016/J.Nano.2016.01.003  0.409
2016 Pati S, Nie B, Arnold RD, Cummings BS. Extraction, chromatographic and mass spectrometric methods for lipid analysis. Biomedical Chromatography : Bmc. PMID 26762903 DOI: 10.1002/Bmc.3683  0.501
2014 Quach ND, Mock JN, Scholpa NE, Eggert MW, Payré C, Lambeau G, Arnold RD, Cummings BS. Role of the phospholipase A2 receptor in liposome drug delivery in prostate cancer cells Molecular Pharmaceutics. 11: 3443-3451. PMID 25189995 DOI: 10.1021/Mp500174P  0.627
2014 Scholpa NE, Zhang X, Kolli RT, Cummings BS. Epigenetic changes in p21 expression in renal cells after exposure to bromate. Toxicological Sciences : An Official Journal of the Society of Toxicology. 141: 432-40. PMID 25015661 DOI: 10.1093/Toxsci/Kfu138  0.318
2014 Quach ND, Arnold RD, Cummings BS. Secretory phospholipase A2 enzymes as pharmacological targets for treatment of disease. Biochemical Pharmacology. 90: 338-48. PMID 24907600 DOI: 10.1016/J.Bcp.2014.05.022  0.523
2013 McGinnis AC, Cummings BS, Bartlett MG. Ion exchange liquid chromatography method for the direct determination of small ribonucleic acids. Analytica Chimica Acta. 799: 57-67. PMID 24091375 DOI: 10.1016/J.Aca.2013.08.040  0.31
2013 Mock JN, Costyn LJ, Wilding SL, Arnold RD, Cummings BS. Evidence for distinct mechanisms of uptake and antitumor activity of secretory phospholipase A2 responsive liposome in prostate cancer Integrative Biology (United Kingdom). 5: 172-182. PMID 22890797 DOI: 10.1039/C2Ib20108A  0.633
2012 Mock JN, Taliaferro JP, Lu X, Patel SK, Cummings BS, Long TE. Haloenol pyranones and morpholinones as antineoplastic agents of prostate cancer Bioorganic and Medicinal Chemistry Letters. 22: 4854-4858. PMID 22677312 DOI: 10.1016/J.Bmcl.2012.05.038  0.402
2012 Eaddy AC, Cummings BS, McHowat J, Schnellmann RG. The role of endoplasmic reticulum Ca2+-independent phospholipase a2γ in oxidant-induced lipid peroxidation, Ca2+ release, and renal cell death. Toxicological Sciences : An Official Journal of the Society of Toxicology. 128: 544-52. PMID 22584685 DOI: 10.1093/Toxsci/Kfs175  0.302
2011 Zhu G, Alhamhoom Y, Cummings BS, Arnold RD. Synthesis of lipids for development of multifunctional lipid-based drug-carriers. Bioorganic & Medicinal Chemistry Letters. 21: 6370-5. PMID 21955941 DOI: 10.1016/J.Bmcl.2011.08.103  0.521
2011 Zhang X, Bull RJ, Fisher J, Cotruvo JA, Cummings BS. The synergistic effect of sodium chlorite and bromochloroacetic acid on BrO3(-)-induced renal cell death. Toxicology. 289: 151-9. PMID 21864635 DOI: 10.1016/J.Tox.2011.08.008  0.326
2011 Aljuffali IA, Mock JN, Costyn LJ, Nguyen H, Nagy T, Cummings BS, Arnold RD. Enhanced antitumor activity of low-dose continuous administration schedules of topotecan in prostate cancer. Cancer Biology & Therapy. 12: 407-20. PMID 21709443 DOI: 10.4161/Cbt.12.5.15950  0.573
2011 Zhu G, Mock JN, Aljuffali I, Cummings BS, Arnold RD. Secretory phospholipase A 2 responsive liposomes Journal of Pharmaceutical Sciences. 100: 3146-3159. PMID 21455978 DOI: 10.1002/Jps.22530  0.524
2010 Sun B, Zhang X, Yonz C, Cummings BS. Inhibition of calcium-independent phospholipase A2 activates p38 MAPK signaling pathways during cytostasis in prostate cancer cells. Biochemical Pharmacology. 79: 1727-35. PMID 20171194 DOI: 10.1016/J.Bcp.2010.02.005  0.367
2010 Zhang X, De Silva D, Sun B, Fisher J, Bull RJ, Cotruvo JA, Cummings BS. Cellular and molecular mechanisms of bromate-induced cytotoxicity in human and rat kidney cells. Toxicology. 269: 13-23. PMID 20067818 DOI: 10.1016/J.Tox.2010.01.002  0.324
2009 Jain S, Zhang X, Khandelwal PJ, Saunders AJ, Cummings BS, Oelkers P. Characterization of human lysophospholipid acyltransferase 3. Journal of Lipid Research. 50: 1563-70. PMID 19351971 DOI: 10.1194/Jlr.M800398-Jlr200  0.334
2008 Hooks SB, Cummings BS. Role of Ca2+-independent phospholipase A2 in cell growth and signaling. Biochemical Pharmacology. 76: 1059-67. PMID 18775417 DOI: 10.1016/J.Bcp.2008.07.044  0.324
2008 Sun B, Zhang X, Talathi S, Cummings BS. Inhibition of Ca2+-independent phospholipase A2 decreases prostate cancer cell growth by p53-dependent and independent mechanisms Journal of Pharmacology and Experimental Therapeutics. 326: 59-68. PMID 18441250 DOI: 10.1124/Jpet.108.138958  0.418
2008 Kinsey GR, Blum JL, Covington MD, Cummings BS, McHowat J, Schnellmann RG. Decreased iPLA2gamma expression induces lipid peroxidation and cell death and sensitizes cells to oxidant-induced apoptosis. Journal of Lipid Research. 49: 1477-87. PMID 18398221 DOI: 10.1194/Jlr.M800030-Jlr200  0.32
2007 Cummings BS. Phospholipase A2 as targets for anti-cancer drugs. Biochemical Pharmacology. 74: 949-59. PMID 17531957 DOI: 10.1016/J.Bcp.2007.04.021  0.409
2007 Peterson B, Knotts T, Cummings BS. Involvement of Ca2+-independent phospholipase A2 isoforms in oxidant-induced neural cell death. Neurotoxicology. 28: 150-60. PMID 17046062 DOI: 10.1016/J.Neuro.2006.09.006  0.353
2006 Saavedra G, Zhang W, Peterson B, Cummings BS. Differential roles for cytosolic and microsomal Ca2+-independent phospholipase A2 in cell growth and maintenance of phospholipids. The Journal of Pharmacology and Experimental Therapeutics. 318: 1211-9. PMID 16763094 DOI: 10.1124/Jpet.106.105650  0.361
2005 Zhang L, Peterson BL, Cummings BS. The effect of inhibition of Ca2+-independent phospholipase A2 on chemotherapeutic-induced death and phospholipid profiles in renal cells. Biochemical Pharmacology. 70: 1697-706. PMID 16226224 DOI: 10.1016/J.Bcp.2005.09.008  0.371
2005 Kinsey GR, Cummings BS, Beckett CS, Saavedra G, Zhang W, McHowat J, Schnellmann RG. Identification and distribution of endoplasmic reticulum iPLA2. Biochemical and Biophysical Research Communications. 327: 287-93. PMID 15629460 DOI: 10.1016/J.Bbrc.2004.12.016  0.322
2004 Cummings BS, Schnellmann RG. Measurement of cell death in mammalian cells. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit 12.8. PMID 22294120 DOI: 10.1002/0471141755.Ph1208S25  0.305
2004 Cummings BS, Kinsey GR, Bolchoz LJ, Schnellmann RG. Identification of caspase-independent apoptosis in epithelial and cancer cells. The Journal of Pharmacology and Experimental Therapeutics. 310: 126-34. PMID 15028782 DOI: 10.1124/Jpet.104.065862  0.338
2004 Cummings BS, McHowat J, Schnellmann RG. Role of an endoplasmic reticulum Ca2+-independent phospholipase A2 in cisplatin-induced renal cell apoptosis. The Journal of Pharmacology and Experimental Therapeutics. 308: 921-8. PMID 14634037 DOI: 10.1124/Jpet.103.060541  0.31
2002 Cummings BS, McHowat J, Schnellmann RG. Role of an endoplasmic reticulum Ca(2+)-independent phospholipase A(2) in oxidant-induced renal cell death. American Journal of Physiology. Renal Physiology. 283: F492-8. PMID 12167600 DOI: 10.1152/Ajprenal.00022.2002  0.328
2000 Cummings BS, Zangar RC, Novak RF, Lash LH. Cytotoxicity of trichloroethylene and S-(1, 2-dichlorovinyl)-L-cysteine in primary cultures of rat renal proximal tubular and distal tubular cells. Toxicology. 150: 83-98. PMID 10996665 DOI: 10.1016/S0300-483X(00)00252-3  0.343
2000 Cummings BS, Lash LH. Metabolism and toxicity of trichloroethylene and S-(1,2-dichlorovinyl)-L-cysteine in freshly isolated human proximal tubular cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 53: 458-66. PMID 10696794 DOI: 10.1093/Toxsci/53.2.458  0.33
2000 Cummings BS, Parker JC, Lash LH. Role of cytochrome P450 and glutathione S-transferase alpha in the metabolism and cytotoxicity of trichloroethylene in rat kidney. Biochemical Pharmacology. 59: 531-43. PMID 10660119 DOI: 10.1016/S0006-2952(99)00374-3  0.332
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