Year |
Citation |
Score |
2023 |
Meade RK, Long JE, Jinich A, Rhee KY, Ashbrook DG, Williams RW, Sassetti CM, Smith CM. Genome-wide screen identifies host loci that modulate M. tuberculosis fitness in immunodivergent mice. G3 (Bethesda, Md.). PMID 37405387 DOI: 10.1093/g3journal/jkad147 |
0.301 |
|
2022 |
Melzer ES, Kado T, García-Heredia A, Gupta KR, Meniche X, Morita YS, Sassetti CM, Rego EH, Siegrist MS. Cell Wall Damage Reveals Spatial Flexibility in Peptidoglycan Synthesis and a Nonredundant Role for RodA in Mycobacteria. Journal of Bacteriology. e0054021. PMID 35543537 DOI: 10.1128/jb.00540-21 |
0.792 |
|
2022 |
Koh EI, Oluoch PO, Ruecker N, Proulx MK, Soni V, Murphy KC, Papavinasasundaram K, Reames CJ, Trujillo C, Zaveri A, Zimmerman MD, Aslebagh R, Baker RE, Shaffer SA, Guinn KM, ... ... Sassetti CM, et al. Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy. Proceedings of the National Academy of Sciences of the United States of America. 119: e2201632119. PMID 35380903 DOI: 10.1073/pnas.2201632119 |
0.418 |
|
2021 |
Choudhery S, Brown AJ, Akusobi C, Rubin EJ, Sassetti CM, Ioerger TR. Modeling Site-Specific Nucleotide Biases Affecting Himar1 Transposon Insertion Frequencies in TnSeq Data Sets. Msystems. e0087621. PMID 34665010 DOI: 10.1128/mSystems.00876-21 |
0.431 |
|
2020 |
Shamma F, Papavinasasundaram K, Quintanilla SY, Bandekar A, Sassetti C, Boutte CC. Phosphorylation on PstP regulates cell wall metabolism and antibiotic tolerance in . Journal of Bacteriology. PMID 33257524 DOI: 10.1128/JB.00563-20 |
0.703 |
|
2020 |
Sutiwisesak R, Hicks ND, Boyce S, Murphy KC, Papavinasasundaram K, Carpenter SM, Boucau J, Joshi N, Le Gall S, Fortune SM, Sassetti CM, Behar SM. A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response. Plos Pathogens. 16: e1009000. PMID 33075106 DOI: 10.1371/journal.ppat.1009000 |
0.551 |
|
2020 |
Lee J, Boyce S, Powers J, Baer C, Sassetti CM, Behar SM. CD11cHi monocyte-derived macrophages are a major cellular compartment infected by Mycobacterium tuberculosis. Plos Pathogens. 16: e1008621. PMID 32544188 DOI: 10.1371/Journal.Ppat.1008621 |
0.306 |
|
2020 |
Lovewell RR, Baer CE, Mishra BB, Smith CM, Sassetti CM. Granulocytes act as a niche for Mycobacterium tuberculosis growth. Mucosal Immunology. PMID 32483198 DOI: 10.1038/S41385-020-0300-Z |
0.344 |
|
2019 |
Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N, Delano K, Da Silva I, Davis J, Gallo C, Gardner M, ... ... Sassetti CM, et al. Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes. Nature. PMID 31217586 DOI: 10.1038/S41586-019-1315-Z |
0.42 |
|
2017 |
Rothchild AC, Stowell B, Goyal G, Nunes-Alves C, Yang Q, Papavinasasundaram K, Sassetti CM, Dranoff G, Chen X, Lee J, Behar SM. Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection. Mbio. 8. PMID 29066547 DOI: 10.1128/Mbio.01514-17 |
0.302 |
|
2017 |
Rock JM, Hopkins FF, Chavez A, Diallo M, Chase MR, Gerrick ER, Pritchard JR, Church GM, Rubin EJ, Sassetti CM, Schnappinger D, Fortune SM. Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform. Nature Microbiology. 2: 16274. PMID 28165460 DOI: 10.1038/Nmicrobiol.2016.274 |
0.657 |
|
2017 |
DeJesus MA, Gerrick ER, Xu W, Park SW, Long JE, Boutte CC, Rubin EJ, Schnappinger D, Ehrt S, Fortune SM, Sassetti CM, Ioerger TR. Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis. Mbio. 8. PMID 28096490 DOI: 10.1128/Mbio.02133-16 |
0.759 |
|
2016 |
Boutte CC, Baer CE, Papavinasasundaram K, Liu W, Chase MR, Meniche X, Fortune SM, Sassetti CM, Ioerger TR, Rubin EJ. A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis. Elife. 5. PMID 27304077 DOI: 10.7554/Elife.14590 |
0.779 |
|
2016 |
Boutte CC, Baer CE, Papavinasasundaram K, Liu W, Chase MR, Meniche X, Fortune SM, Sassetti CM, Ioerger TR, Rubin EJ. Author response: A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis Elife. DOI: 10.7554/Elife.14590.018 |
0.746 |
|
2015 |
Kieser KJ, Baranowski C, Chao MC, Long JE, Sassetti CM, Waldor MK, Sacchettini JC, Ioerger TR, Rubin EJ. Peptidoglycan synthesis in Mycobacterium tuberculosis is organized into networks with varying drug susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 112: 13087-92. PMID 26438867 DOI: 10.1073/Pnas.1514135112 |
0.769 |
|
2015 |
Kieser KJ, Boutte CC, Kester JC, Baer CE, Barczak AK, Meniche X, Chao MC, Rego EH, Sassetti CM, Fortune SM, Rubin EJ. Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria. Plos Pathogens. 11: e1005010. PMID 26114871 DOI: 10.1371/Journal.Ppat.1005010 |
0.7 |
|
2015 |
Feltcher ME, Gunawardena HP, Zulauf KE, Malik S, Griffin JE, Sassetti CM, Chen X, Braunstein M. Label-free Quantitative Proteomics Reveals a Role for the Mycobacterium tuberculosis SecA2 Pathway in Exporting Solute Binding Proteins and Mce Transporters to the Cell Wall. Molecular & Cellular Proteomics : McP. 14: 1501-16. PMID 25813378 DOI: 10.1074/Mcp.M114.044685 |
0.306 |
|
2015 |
Baer CE, Rubin EJ, Sassetti CM. New insights into TB physiology suggest untapped therapeutic opportunities. Immunological Reviews. 264: 327-43. PMID 25703570 DOI: 10.1111/Imr.12267 |
0.42 |
|
2014 |
Trauner A, Sassetti CM, Rubin EJ. Genetic Strategies for Identifying New Drug Targets. Microbiology Spectrum. 2: MGM2-0030-2013. PMID 26104208 DOI: 10.1128/Microbiolspec.Mgm2-0030-2013 |
0.388 |
|
2014 |
Meniche X, Otten R, Siegrist MS, Baer CE, Murphy KC, Bertozzi CR, Sassetti CM. Subpolar addition of new cell wall is directed by DivIVA in mycobacteria. Proceedings of the National Academy of Sciences of the United States of America. 111: E3243-51. PMID 25049412 DOI: 10.1073/pnas.1402158111 |
0.574 |
|
2013 |
Ioerger TR, O'Malley T, Liao R, Guinn KM, Hickey MJ, Mohaideen N, Murphy KC, Boshoff HI, Mizrahi V, Rubin EJ, Sassetti CM, Barry CE, Sherman DR, Parish T, Sacchettini JC. Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis. Plos One. 8: e75245. PMID 24086479 DOI: 10.1371/Journal.Pone.0075245 |
0.461 |
|
2013 |
Shell SS, Prestwich EG, Baek SH, Shah RR, Sassetti CM, Dedon PC, Fortune SM. DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis. Plos Pathogens. 9: e1003419. PMID 23853579 DOI: 10.1371/Journal.Ppat.1003419 |
0.58 |
|
2013 |
DeJesus MA, Zhang YJ, Sassetti CM, Rubin EJ, Sacchettini JC, Ioerger TR. Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries. Bioinformatics (Oxford, England). 29: 695-703. PMID 23361328 DOI: 10.1093/Bioinformatics/Btt043 |
0.551 |
|
2013 |
Zhang YJ, Ioerger TR, Huttenhower C, Long JE, Sassetti CM, Sacchettini JC, Rubin EJ. Correction: Global Assessment of Genomic Regions Required for Growth in Mycobacterium tuberculosis Plos Pathogens. 9. DOI: 10.1371/Annotation/4669E9E7-Fd12-4A01-Be2A-617B956Ec0Bb |
0.564 |
|
2012 |
Zhang YJ, Ioerger TR, Huttenhower C, Long JE, Sassetti CM, Sacchettini JC, Rubin EJ. Global assessment of genomic regions required for growth in Mycobacterium tuberculosis. Plos Pathogens. 8: e1002946. PMID 23028335 DOI: 10.1371/Journal.Ppat.1002946 |
0.625 |
|
2012 |
Lee HJ, Lang PT, Fortune SM, Sassetti CM, Alber T. Cyclic AMP regulation of protein lysine acetylation in Mycobacterium tuberculosis. Nature Structural & Molecular Biology. 19: 811-8. PMID 22773105 DOI: 10.1038/Nsmb.2318 |
0.561 |
|
2012 |
Gee CL, Papavinasasundaram KG, Blair SR, Baer CE, Falick AM, King DS, Griffin JE, Venghatakrishnan H, Zukauskas A, Wei JR, Dhiman RK, Crick DC, Rubin EJ, Sassetti CM, Alber T. A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria. Science Signaling. 5: ra7. PMID 22275220 DOI: 10.1126/Scisignal.2002525 |
0.435 |
|
2011 |
Griffin JE, Gawronski JD, Dejesus MA, Ioerger TR, Akerley BJ, Sassetti CM. High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism. Plos Pathogens. 7: e1002251. PMID 21980284 DOI: 10.1371/Journal.Ppat.1002251 |
0.333 |
|
2011 |
Baek SH, Li AH, Sassetti CM. Metabolic regulation of mycobacterial growth and antibiotic sensitivity Plos Biology. 9. PMID 21629732 DOI: 10.1371/journal.pbio.1001065 |
0.305 |
|
2011 |
Wei JR, Krishnamoorthy V, Murphy K, Kim JH, Schnappinger D, Alber T, Sassetti CM, Rhee KY, Rubin EJ. Depletion of antibiotic targets has widely varying effects on growth. Proceedings of the National Academy of Sciences of the United States of America. 108: 4176-81. PMID 21368134 DOI: 10.1073/Pnas.1018301108 |
0.41 |
|
2011 |
Gee CL, Papavinasasundaram KG, Blair SR, Baer CE, Falick AM, King DS, Griffin J, Venghatakrishnan H, Wei J-, Rubin EJ, Sassetti CM, Alber T. A pseudokinase mediates cell wall integrity inMycobacterium tuberculosis Acta Crystallographica Section a Foundations of Crystallography. 67: C62-C63. DOI: 10.1107/S0108767311098503 |
0.489 |
|
2010 |
Sassetti CM, Rubin EJ. Relics of selection in the mycobacterial genome. Nature Genetics. 42: 476-8. PMID 20502489 DOI: 10.1038/Ng0610-476 |
0.434 |
|
2010 |
Ioerger TR, Feng Y, Ganesula K, Chen X, Dobos KM, Fortune S, Jacobs WR, Mizrahi V, Parish T, Rubin E, Sassetti C, Sacchettini JC. Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories. Journal of Bacteriology. 192: 3645-53. PMID 20472797 DOI: 10.1128/Jb.00166-10 |
0.645 |
|
2009 |
Murry JP, Pandey AK, Sassetti CM, Rubin EJ. Phthiocerol dimycocerosate transport is required for resisting interferon-gamma-independent immunity. The Journal of Infectious Diseases. 200: 774-82. PMID 19622047 DOI: 10.1086/605128 |
0.737 |
|
2009 |
Pandey AK, Yang Y, Jiang Z, Fortune SM, Coulombe F, Behr MA, Fitzgerald KA, Sassetti CM, Kelliher MA. NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis. Plos Pathogens. 5: e1000500. PMID 19578435 DOI: 10.1371/Journal.Ppat.1000500 |
0.598 |
|
2009 |
Pandey AK, Raman S, Proff R, Joshi S, Kang CM, Rubin EJ, Husson RN, Sassetti CM. Nitrile-inducible gene expression in mycobacteria. Tuberculosis (Edinburgh, Scotland). 89: 12-6. PMID 18801704 DOI: 10.1016/J.Tube.2008.07.007 |
0.473 |
|
2008 |
Murry JP, Sassetti CM, Lane JM, Xie Z, Rubin EJ. Transposon site hybridization in Mycobacterium tuberculosis. Methods in Molecular Biology (Clifton, N.J.). 416: 45-59. PMID 18392960 DOI: 10.1007/978-1-59745-321-9_4 |
0.728 |
|
2007 |
Sassetti CM, Rubin EJ. The open book of infectious diseases. Nature Medicine. 13: 279-80. PMID 17342136 DOI: 10.1038/Nm0307-279 |
0.339 |
|
2006 |
Joshi SM, Pandey AK, Capite N, Fortune SM, Rubin EJ, Sassetti CM. Characterization of mycobacterial virulence genes through genetic interaction mapping. Proceedings of the National Academy of Sciences of the United States of America. 103: 11760-5. PMID 16868085 DOI: 10.1073/Pnas.0603179103 |
0.65 |
|
2005 |
Murry J, Sassetti CM, Moreira J, Lane J, Rubin EJ. A new site-specific integration system for mycobacteria. Tuberculosis (Edinburgh, Scotland). 85: 317-23. PMID 16256438 DOI: 10.1016/J.Tube.2005.08.016 |
0.716 |
|
2005 |
Fortune SM, Jaeger A, Sarracino DA, Chase MR, Sassetti CM, Sherman DR, Bloom BR, Rubin EJ. Mutually dependent secretion of proteins required for mycobacterial virulence. Proceedings of the National Academy of Sciences of the United States of America. 102: 10676-81. PMID 16030141 DOI: 10.1073/Pnas.0504922102 |
0.627 |
|
2004 |
Rengarajan J, Sassetti CM, Naroditskaya V, Sloutsky A, Bloom BR, Rubin EJ. The folate pathway is a target for resistance to the drug para-aminosalicylic acid (PAS) in mycobacteria. Molecular Microbiology. 53: 275-82. PMID 15225321 DOI: 10.1111/J.1365-2958.2004.04120.X |
0.412 |
|
2003 |
Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 100: 12989-94. PMID 14569030 DOI: 10.1073/Pnas.2134250100 |
0.497 |
|
2003 |
Sassetti CM, Boyd DH, Rubin EJ. Genes required for mycobacterial growth defined by high density mutagenesis. Molecular Microbiology. 48: 77-84. PMID 12657046 DOI: 10.1046/J.1365-2958.2003.03425.X |
0.51 |
|
2002 |
Sassetti C, Rubin EJ. Genomic analyses of microbial virulence. Current Opinion in Microbiology. 5: 27-32. PMID 11834365 DOI: 10.1016/S1369-5274(02)00281-3 |
0.478 |
|
2001 |
Sassetti CM, Boyd DH, Rubin EJ. Comprehensive identification of conditionally essential genes in mycobacteria. Proceedings of the National Academy of Sciences of the United States of America. 98: 12712-7. PMID 11606763 DOI: 10.1073/Pnas.231275498 |
0.441 |
|
2000 |
Papadopoulos EJ, Fitzhugh DJ, Tkaczyk C, Gilfillan AM, Sassetti C, Metcalfe DD, Hwang ST. Mast cells migrate, but do not degranulate, in response to fractalkine, a membrane-bound chemokine expressed constitutively in diverse cells of the skin. European Journal of Immunology. 30: 2355-2361. PMID 10940926 DOI: 10.1002/1521-4141(2000)30:8<2355::Aid-Immu2355>3.0.Co;2-# |
0.302 |
|
1999 |
Papadopoulos EJ, Sassetti C, Saeki H, Yamada N, Kawamura T, Fitzhugh DJ, Saraf MA, Schall T, Blauvelt A, Rosen SD, Hwang ST. Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation. European Journal of Immunology. 29: 2551-9. PMID 10458770 DOI: 10.1002/(Sici)1521-4141(199908)29:08<2551::Aid-Immu2551>3.0.Co;2-T |
0.305 |
|
1998 |
Saeki H, Sassetti C, Rosen SD, Schall TJ, Hwang ST. Fractalkine, a novel CX3C chemokine, is expressed by epidermal melanocytes and langerhans cells Journal of Dermatological Science. 16: S180. DOI: 10.1016/S0923-1811(98)84077-2 |
0.307 |
|
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