Year |
Citation |
Score |
2022 |
Strom A, Shah R, Dolot R, Rogers MS, Tong CL, Wang D, Xia Y, Lipscomb JD, Wagner CR. Dynamic Long-Range Interactions Influence Substrate Binding and Catalysis by Human Histidine Triad Nucleotide-Binding Proteins (HINTs), Key Regulators of Multiple Cellular Processes and Activators of Antiviral ProTides. Biochemistry. PMID 36398895 DOI: 10.1021/acs.biochem.2c00506 |
0.591 |
|
2021 |
Strom A, Shah R, Wagner CR. "Switching On" Enzyme Substrate Specificity Analysis with a Fluorescent Competitive Inhibitor. Biochemistry. PMID 33513008 DOI: 10.1021/acs.biochem.0c00954 |
0.573 |
|
2019 |
Shah R, Peterson C, Strom A, Dillenburg M, Finzel BC, Kitto KF, Fairbanks CA, Wilcox GL, Wagner CR. Inhibition of Hint1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice. Acs Chemical Neuroscience. PMID 31503445 DOI: 10.1021/Acschemneuro.9B00432 |
0.499 |
|
2018 |
Shah RM, Maize KM, West HT, Strom AM, Finzel BC, Wagner CR. Structure and Functional Characterization of Human Histidine Triad Nucleotide Binding Protein 1 Mutations Associated with Inherited Axonal Neuropathy with Neuromyotonia. Journal of Molecular Biology. PMID 29787766 DOI: 10.1016/J.Jmb.2018.05.028 |
0.558 |
|
2017 |
Shah R, Zhou A, Wagner CR. Switch-on fluorescent/FRET probes to study human histidine triad nucleotide binding protein 1 (hHint1), a novel target for opioid tolerance and neuropathic pain. Organic & Biomolecular Chemistry. 15: 10230-10237. PMID 29177353 DOI: 10.1039/C7Ob02472J |
0.557 |
|
2017 |
Maize KM, Shah R, Strom A, Kumarapperuma SC, Zhou AL, Wagner CR, Finzel BC. A Crystal Structure-Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides. Molecular Pharmaceutics. PMID 28968488 DOI: 10.1021/Acs.Molpharmaceut.7B00664 |
0.676 |
|
2017 |
Okon A, Matos de Souza MR, Shah R, Amorim R, da Costa LJ, Wagner CR. Anchimerically Activatable Antiviral ProTides. Acs Medicinal Chemistry Letters. 8: 958-962. PMID 28947944 DOI: 10.1021/Acsmedchemlett.7B00277 |
0.5 |
|
2017 |
Shah R, Chou TF, Maize KM, Strom A, Finzel BC, Wagner CR. Inhibition by divalent metal ions of human histidine triad nucleotide binding protein1 (hHint1), a regulator of opioid analgesia and neuropathic pain. Biochemical and Biophysical Research Communications. PMID 28739258 DOI: 10.1016/J.Bbrc.2017.07.111 |
0.613 |
|
2017 |
Shah R, Maize KM, Zhou X, Finzel BC, Wagner CR. Caught before Released: Structural Mapping of the Reaction Trajectory for the Sofosbuvir Activating Enzyme, Human Histidine Triad Nucleotide Binding Protein 1 (hHint1). Biochemistry. PMID 28691797 DOI: 10.1021/Acs.Biochem.7B00148 |
0.61 |
|
2016 |
Shah R, Strom A, Zhou A, Maize KM, Finzel BC, Wagner CR. Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1. Acs Medicinal Chemistry Letters. 7: 780-4. PMID 27563403 DOI: 10.1021/Acsmedchemlett.6B00169 |
0.542 |
|
2016 |
Shah R, Petersburg J, Gangar AC, Fegan A, Wagner CR, Kumarapperuma SC. In vivo Evaluation of Site-specifically PEGylated Chemically Self-assembled Protein Nanostructures. Molecular Pharmaceutics. PMID 26985775 DOI: 10.1021/Acs.Molpharmaceut.6B00110 |
0.537 |
|
2015 |
Garzón J, Herrero-Labrador R, Rodríguez-Muñoz M, Shah R, Vicente-Sánchez A, Wagner CR, Sánchez-Blázquez P. HINT1 protein: a new therapeutic target to enhance opioid antinociception and block mechanical allodynia. Neuropharmacology. 89: 412-23. PMID 25445489 DOI: 10.1016/J.Neuropharm.2014.10.022 |
0.51 |
|
2013 |
Rashidian M, Mahmoodi MM, Shah R, Dozier JK, Wagner CR, Distefano MD. A highly efficient catalyst for oxime ligation and hydrazone-oxime exchange suitable for bioconjugation. Bioconjugate Chemistry. 24: 333-42. PMID 23425124 DOI: 10.1021/Bc3004167 |
0.527 |
|
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