Rachit Shah - Publications

Affiliations: 
Broad Institute of MIT and Harvard, USA 

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Strom A, Shah R, Dolot R, Rogers MS, Tong CL, Wang D, Xia Y, Lipscomb JD, Wagner CR. Dynamic Long-Range Interactions Influence Substrate Binding and Catalysis by Human Histidine Triad Nucleotide-Binding Proteins (HINTs), Key Regulators of Multiple Cellular Processes and Activators of Antiviral ProTides. Biochemistry. PMID 36398895 DOI: 10.1021/acs.biochem.2c00506  0.591
2021 Strom A, Shah R, Wagner CR. "Switching On" Enzyme Substrate Specificity Analysis with a Fluorescent Competitive Inhibitor. Biochemistry. PMID 33513008 DOI: 10.1021/acs.biochem.0c00954  0.573
2019 Shah R, Peterson C, Strom A, Dillenburg M, Finzel BC, Kitto KF, Fairbanks CA, Wilcox GL, Wagner CR. Inhibition of Hint1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice. Acs Chemical Neuroscience. PMID 31503445 DOI: 10.1021/Acschemneuro.9B00432  0.499
2018 Shah RM, Maize KM, West HT, Strom AM, Finzel BC, Wagner CR. Structure and Functional Characterization of Human Histidine Triad Nucleotide Binding Protein 1 Mutations Associated with Inherited Axonal Neuropathy with Neuromyotonia. Journal of Molecular Biology. PMID 29787766 DOI: 10.1016/J.Jmb.2018.05.028  0.558
2017 Shah R, Zhou A, Wagner CR. Switch-on fluorescent/FRET probes to study human histidine triad nucleotide binding protein 1 (hHint1), a novel target for opioid tolerance and neuropathic pain. Organic & Biomolecular Chemistry. 15: 10230-10237. PMID 29177353 DOI: 10.1039/C7Ob02472J  0.557
2017 Maize KM, Shah R, Strom A, Kumarapperuma SC, Zhou AL, Wagner CR, Finzel BC. A Crystal Structure-Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides. Molecular Pharmaceutics. PMID 28968488 DOI: 10.1021/Acs.Molpharmaceut.7B00664  0.676
2017 Okon A, Matos de Souza MR, Shah R, Amorim R, da Costa LJ, Wagner CR. Anchimerically Activatable Antiviral ProTides. Acs Medicinal Chemistry Letters. 8: 958-962. PMID 28947944 DOI: 10.1021/Acsmedchemlett.7B00277  0.5
2017 Shah R, Chou TF, Maize KM, Strom A, Finzel BC, Wagner CR. Inhibition by divalent metal ions of human histidine triad nucleotide binding protein1 (hHint1), a regulator of opioid analgesia and neuropathic pain. Biochemical and Biophysical Research Communications. PMID 28739258 DOI: 10.1016/J.Bbrc.2017.07.111  0.613
2017 Shah R, Maize KM, Zhou X, Finzel BC, Wagner CR. Caught before Released: Structural Mapping of the Reaction Trajectory for the Sofosbuvir Activating Enzyme, Human Histidine Triad Nucleotide Binding Protein 1 (hHint1). Biochemistry. PMID 28691797 DOI: 10.1021/Acs.Biochem.7B00148  0.61
2016 Shah R, Strom A, Zhou A, Maize KM, Finzel BC, Wagner CR. Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1. Acs Medicinal Chemistry Letters. 7: 780-4. PMID 27563403 DOI: 10.1021/Acsmedchemlett.6B00169  0.542
2016 Shah R, Petersburg J, Gangar AC, Fegan A, Wagner CR, Kumarapperuma SC. In vivo Evaluation of Site-specifically PEGylated Chemically Self-assembled Protein Nanostructures. Molecular Pharmaceutics. PMID 26985775 DOI: 10.1021/Acs.Molpharmaceut.6B00110  0.537
2015 Garzón J, Herrero-Labrador R, Rodríguez-Muñoz M, Shah R, Vicente-Sánchez A, Wagner CR, Sánchez-Blázquez P. HINT1 protein: a new therapeutic target to enhance opioid antinociception and block mechanical allodynia. Neuropharmacology. 89: 412-23. PMID 25445489 DOI: 10.1016/J.Neuropharm.2014.10.022  0.51
2013 Rashidian M, Mahmoodi MM, Shah R, Dozier JK, Wagner CR, Distefano MD. A highly efficient catalyst for oxime ligation and hydrazone-oxime exchange suitable for bioconjugation. Bioconjugate Chemistry. 24: 333-42. PMID 23425124 DOI: 10.1021/Bc3004167  0.527
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