Year |
Citation |
Score |
2011 |
Holmes RS, Hempel J. Comparative studies of vertebrate aldehyde dehydrogenase 3: Sequences, structures, phylogeny and evolution. Evidence for a mammalian origin for the ALDH3A1 gene Chemico-Biological Interactions. 191: 113-121. PMID 21296057 DOI: 10.1016/J.Cbi.2011.01.014 |
0.392 |
|
2009 |
Hempel J, Kraut A, Wymore T. Gamma glutamyl semialdehyde dehydrogenase: Simulations on native and mutant forms support the importance of outer shell lysines Chemico-Biological Interactions. 178: 75-78. PMID 19000660 DOI: 10.1016/J.Cbi.2008.10.009 |
0.356 |
|
2007 |
Wymore T, Deerfield DW, Hempel J. Mechanistic implications of the cysteine-nicotinamide adduct in aldehyde dehydrogenase based on quantum mechanical/molecular mechanical simulations Biochemistry. 46: 9495-9506. PMID 17655326 DOI: 10.1021/Bi700555G |
0.327 |
|
2004 |
Wymore T, Hempel J, Cho SS, Mackerell AD, Nicholas HB, Deerfield DW. Molecular recognition of aldehydes by aldehyde dehydrogenase and mechanism of nucleophile activation. Proteins. 57: 758-71. PMID 15390260 DOI: 10.1002/Prot.20256 |
0.345 |
|
2003 |
Wymore T, Deerfield DW, Field MJ, Hempel J, Nicholas HB. Initial catalytic events in class 3 aldehyde dehydrogenase: MM and QM/MM simulations. Chemico-Biological Interactions. 143: 75-84. PMID 12604191 DOI: 10.1016/S0009-2797(02)00175-8 |
0.363 |
|
2003 |
Hempel J, Perozich J, Wymore T, Nicholas HB. An algorithm for identification and ranking of family-specific residues, applied to the ALDH3 family. Chemico-Biological Interactions. 143: 23-28. PMID 12604185 DOI: 10.1016/S0009-2797(02)00165-5 |
0.35 |
|
2001 |
Wymore T, Nicholas HB, Hempel J. Molecular dynamics simulation of class 3 aldehyde dehydrogenase. Chemico-Biological Interactions. 130: 201-207. PMID 11306044 DOI: 10.1016/S0009-2797(00)00278-7 |
0.377 |
|
2001 |
Perozich J, Kuo I, Lindahl R, Hempel J. Coenzyme specificity in aldehyde dehydrogenase Chemico-Biological Interactions. 130: 115-124. PMID 11306036 DOI: 10.1016/S0009-2797(00)00227-1 |
0.4 |
|
2001 |
Hempel J, Lindahl R, Perozich J, Wang BC, Kuo I, Nicholas H. Beyond the catalytic core of ALDH: A web of important residues begins to emerge Chemico-Biological Interactions. 130: 39-46. PMID 11306029 DOI: 10.1016/S0009-2797(00)00220-9 |
0.432 |
|
2001 |
Hempel J, Kuo I, Perozich J, Wang BC, Lindahl R, Nicholas H. Aldehyde dehydrogenase: Maintaining critical active site geometry at motif 8 in the class 3 enzyme European Journal of Biochemistry. 268: 722-726. PMID 11168411 DOI: 10.1046/J.1432-1327.2001.01926.X |
0.433 |
|
2000 |
Perozich J, Kuo I, Wang BC, Boesch JS, Lindahl R, Hempel J. Shifting the NAD/NADP preference in class 3 aldehyde dehydrogenase European Journal of Biochemistry. 267: 6197-6203. PMID 11012673 DOI: 10.1046/J.1432-1327.2000.01697.X |
0.479 |
|
1999 |
Hempel J, Perozich J, Chapman T, Rose J, Boesch JS, Liu ZJ, Lindahl R, Wang BC. Aldehyde dehydrogenase catalytic mechanism: A proposal Advances in Experimental Medicine and Biology. 463: 53-59. PMID 10352669 DOI: 10.1007/978-1-4615-4735-8_7 |
0.397 |
|
1999 |
Perozich J, Nicholas H, Lindahl R, Hempel J. The big book of aldehyde dehydrogenase sequences: An overview of the extended family Advances in Experimental Medicine and Biology. 463: 1-7. PMID 10352663 DOI: 10.1007/978-1-4615-4735-8_1 |
0.362 |
|
1999 |
Perozich J, Nicholas H, Wang BC, Lindahl R, Hempel J. Relationships within the aldehyde dehydrogenase extended family Protein Science. 8: 137-146. PMID 10210192 DOI: 10.1110/Ps.8.1.137 |
0.42 |
|
1998 |
Perozich J, Hempel J, Morris SM. Roles of conserved residues in the arginase family Biochimica Et Biophysica Acta - Protein Structure and Molecular Enzymology. 1382: 23-37. PMID 9507056 DOI: 10.1016/S0167-4838(97)00131-3 |
0.46 |
|
1997 |
Etzel KR, Hempel JD, Koepsel RR. Identification of zinc proteins in rat parotid saliva. Archives of Oral Biology. 42: 173-9. PMID 9134129 DOI: 10.1016/S0003-9969(96)00077-5 |
0.316 |
|
1997 |
Liu ZJ, Sun YJ, Rose J, Chung YJ, Hsiao CD, Chang WR, Kuo I, Perozich J, Lindahl R, Hempel J, Wang BC. The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold. Nature Structural Biology. 4: 317-26. PMID 9095201 DOI: 10.1038/Nsb0497-317 |
0.357 |
|
1997 |
Hempel J, Liu ZJ, Perozich J, Rose J, Lindahl R, Wang BC. Conserved residues in the aldehyde dehydrogenase family: Locations in the class 3 tertiary structure Advances in Experimental Medicine and Biology. 414: 9-13. PMID 9059601 DOI: 10.1007/978-1-4615-5871-2_2 |
0.439 |
|
1997 |
Liu ZJ, Hempel J, Sun J, Rose J, Hsiao D, Chang WR, Chung YJ, Kuo I, Lindahl R, Wang BC. Crystal structure of a class 3 aldehyde dehydrogenase at 2.6 A resolution. Advances in Experimental Medicine and Biology. 414: 1-7. PMID 9059600 DOI: 10.1007/978-1-4615-5871-2_1 |
0.43 |
|
1995 |
Nicholas HB, Persson B, Jörnvall H, Hempel J. Ethanol utilization regulatory protein: Profile alignments give no evidence of origin through aldehyde and alcohol dehydrogenase gene fusion Protein Science. 4: 2621-2624. PMID 8580855 DOI: 10.1002/Pro.5560041221 |
0.302 |
|
1995 |
Duda RL, Hempel J, Michel H, Shabanowitz J, Hunt D, Hendrix RW. Structural transitions during bacteriophage HK97 head assembly Journal of Molecular Biology. 247: 618-635. PMID 7723019 DOI: 10.1016/S0022-2836(05)80143-3 |
0.33 |
|
1995 |
Sun J, Hempel J, Lindahl R, Perozich J, Rose J, Wang BC. Progress toward the tertiary structure of (class 3) aldehyde dehydrogenase Advances in Experimental Medicine and Biology. 372: 71-77. PMID 7484412 DOI: 10.1007/978-1-4615-1965-2_10 |
0.376 |
|
1994 |
Hempel J, Perozich J, Romovacek H, Hinich A, Kuo I, Feingold DS. UDP-glucose dehydrogenase from bovine liver: Primary structure and relationship to other dehydrogenases Protein Science. 3: 1074-1080. PMID 7920253 DOI: 10.1002/Pro.5560030710 |
0.471 |
|
1993 |
Agarwal DP, Eckey R, Hempel J, Goedde HW. Human Liver High Km Aldehyde Dehydrogenase (ALDH4): Properties and Structural Relationship to the Glutamic γ-Semialdehyde Dehydrogenase Advances in Experimental Medicine and Biology. 328: 191-197. PMID 8493898 DOI: 10.1007/978-1-4615-2904-0_21 |
0.343 |
|
1993 |
Hempel J, Nicholas H, Lindahl R. Aldehyde dehydrogenases: Widespread structural and functional diversity within a shared framework Protein Science. 2: 1890-1900. PMID 8268800 DOI: 10.1002/Pro.5560021111 |
0.47 |
|
1992 |
Churchill P, Hempel J, Romovacek H, Zhang WW, Brennan M, Churchill S. Primary structure of rat liver D-beta-hydroxybutyrate dehydrogenase from cDNA and protein analyses: a short-chain alcohol dehydrogenase. Biochemistry. 31: 3793-3799. PMID 1567834 DOI: 10.1021/Bi00130A009 |
0.454 |
|
1992 |
Hempel J, Eckey R, Berie D, Romovacek H, Agarwal DP, Goedde HW. Human liver glutamic γ-semialdehyde dehydrogenase: Structural relationship to the yeast enzyme Comparative Biochemistry and Physiology B. 102: 791-793. PMID 1395511 DOI: 10.1016/0305-0491(92)90081-2 |
0.413 |
|
1991 |
Hempel J, Rose JP, Kuo I, Lindahl R, Wang BC. Rat class 3 aldehyde dehydrogenase: crystals and preliminary analysis. Advances in Experimental Medicine and Biology. 284: 9-11. PMID 2053495 DOI: 10.1007/978-1-4684-5901-2_2 |
0.414 |
|
1991 |
Lindahl R, Hempel J. Aldehyde dehydrogenases: What can be learned from a baker's dozen sequences? Advances in Experimental Medicine and Biology. 284: 1-8. PMID 2053471 DOI: 10.1007/978-1-4684-5901-2_1 |
0.352 |
|
1991 |
Hempel J, Nicholas H, Jörnvall H. Thiol proteases and aldehyde dehydrogenases: evolution from a common thiolesterase precursor? Proteins. 11: 176-183. PMID 1749771 DOI: 10.1002/Prot.340110303 |
0.455 |
|
1990 |
Eckey R, Timmann R, Hempel J, Agarwal DP, Goedde HW. Biochemical, immunological, and molecular characterization of a "high Km" aldehyde dehydrogenase. Advances in Experimental Medicine and Biology. 284: 43-52. PMID 1905102 DOI: 10.1007/978-1-4684-5901-2_6 |
0.372 |
|
1989 |
Hempel J, Harper K, Lindahl R. Inducible (class 3) aldehyde dehydrogenase from rat hepatocellular carcinoma and 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated liver: Distant relationship to the class 1 and 2 enzymes from mammalian liver cytosol/mitochondria Biochemistry. 28: 1160-1167. PMID 2713359 DOI: 10.1021/Bi00429A034 |
0.463 |
|
1988 |
Kaiser R, Holmquist B, Hempel J, Vallee BL, Jörnvall H. Class III human liver alcohol dehydrogenase: A novel structural type equidistantly related to the class I and class II enzymes Biochemistry. 27: 1132-1140. PMID 3365377 DOI: 10.1021/Bi00404A009 |
0.464 |
|
1988 |
Jones DE, Brennan MD, Hempel J, Lindahl R. Cloning and complete nucleotide sequence of a full-length cDNA encoding a catalytically functional tumor-associated aldehyde dehydrogenase Proceedings of the National Academy of Sciences of the United States of America. 85: 1782-1786. PMID 2831537 DOI: 10.1073/Pnas.85.6.1782 |
0.315 |
|
1987 |
Hempel J, Höög J, Jörnvall H. Mitochondrial aldehyde dehydrogenase. Homology of putative targeting sequence to that of carbamyl phosphate synthetase I revealed by correlation of cDNA and protein data. Febs Letters. 222: 95-98. PMID 3653404 DOI: 10.1016/0014-5793(87)80198-9 |
0.368 |
|
1984 |
Jornvall H, Hempel J, Vallee BL. Human liver alcohol dehydrogenase: Amino acid substitution in the β2β2 Oriental isozyme explains functional properties, establishes an active site structure, and parallels mutational exchanges in the yeast enzyme Proceedings of the National Academy of Sciences of the United States of America. 81: 3024-3028. PMID 6374651 DOI: 10.1073/Pnas.81.10.3024 |
0.386 |
|
1984 |
Duester G, Hatfield GW, Bühler R, Hempel J, Jörnvall H, Smith M. Molecular cloning and characterization of a cDNA for the beta subunit of human alcohol dehydrogenase Proceedings of the National Academy of Sciences of the United States of America. 81: 4055-4059. PMID 6330735 DOI: 10.1073/Pnas.81.13.4055 |
0.373 |
|
1984 |
Bühler R, Hempel J, Kaiser R, Zalenski Cd, Wartburg Jv, Jörnvall H. HUMAN LIVER ALCOHOL DEHYDROGENASE: THE PRIMARY STRUCTURE OF THE γ1 PROTEIN CHAIN Febs Journal. 145: 450-453. DOI: 10.1111/J.1432-1033.1984.Tb08576.X |
0.348 |
|
1984 |
Hempel J, Buhler R, Kaiser R, Holmquist B, Zalenski C, Wartburg J, Vallee B, Jornvall H. HUMAN LIVER ALCOHOL DEHYDROGENASE: THE PRIMARY STRUCTURE OF THE beta1 beta1 ISOENZYME European Journal of Biochemistry. 145: 443-445. DOI: 10.1111/J.1432-1033.1984.Tb08574.X |
0.304 |
|
1984 |
Bahr-Lindström Hv, Hempel J, Jörnvall H. The cytoplasmic isoenzyme of horse liver aldehyde dehydrogenase. Relationship to the corresponding human isoenzyme. Febs Journal. 141: 37-42. DOI: 10.1111/J.1432-1033.1984.Tb08153.X |
0.473 |
|
1984 |
Hempel J, Bahr‐Lindström Hv, Jörnvall H. Aldehyde Dehydrogenase From Human Liver: Primary Structure Of The Cytoplasmic Isoenzyme Febs Journal. 141: 21-35. DOI: 10.1111/J.1432-1033.1984.Tb08151.X |
0.483 |
|
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