| Year |
Citation |
Score |
| 2023 |
Nie X, Zhao Y, Tang H, Zhang Z, Liao J, Almodovar-Rivera CM, Sundaresan R, Xie H, Guo L, Wang B, Guan H, Xing Y, Tang W. Development of Phenyl-substituted Isoindolinone- and Benzimidazole-Type Cereblon Ligands for Targeted Protein Degradation. Chembiochem : a European Journal of Chemical Biology. e202300685. PMID 38116854 DOI: 10.1002/cbic.202300685 |
0.601 |
|
| 2023 |
Xie H, Bacabac MS, Ma M, Kim EJ, Wang Y, Wu W, Li L, Xu W, Tang W. Development of Potent and Selective Coactivator-Associated Arginine Methyltransferase 1 (CARM1) Degraders. Journal of Medicinal Chemistry. PMID 37703322 DOI: 10.1021/acs.jmedchem.3c00982 |
0.606 |
|
| 2023 |
Almodóvar-Rivera CM, Zhang Z, Li J, Xie H, Zhao Y, Guo L, Mannhardt MG, Tang W. A Modular Chemistry Platform for the Development of a Cereblon E3 Ligase-based Partial PROTAC Library. Chembiochem : a European Journal of Chemical Biology. e202300482. PMID 37418320 DOI: 10.1002/cbic.202300482 |
0.588 |
|
| 2023 |
Li J, Li C, Zhang Z, Zhang Z, Wu Z, Liao J, Wang Z, McReynolds M, Xie H, Guo L, Fan Q, Peng J, Tang W. A platform for the rapid synthesis of molecular glues (Rapid-Glue) under miniaturized conditions for direct biological screening. European Journal of Medicinal Chemistry. 258: 115567. PMID 37390512 DOI: 10.1016/j.ejmech.2023.115567 |
0.575 |
|
| 2023 |
Xie H, Li C, Tang H, Tandon I, Liao J, Roberts BL, Zhao Y, Tang W. Development of Substituted Phenyl Dihydrouracil as the Novel Achiral Cereblon Ligands for Targeted Protein Degradation. Journal of Medicinal Chemistry. PMID 36749666 DOI: 10.1021/acs.jmedchem.2c01941 |
0.568 |
|
| 2022 |
Donahue K, Xie H, Li M, Gao A, Ma M, Wang Y, Tipton R, Semanik N, Primeau T, Li S, Li L, Tang W, Xu W. Diptoindonesin G is a middle domain HSP90 modulator for cancer treatment. The Journal of Biological Chemistry. 102700. PMID 36395883 DOI: 10.1016/j.jbc.2022.102700 |
0.477 |
|
| 2020 |
Xie H, Yang K, Winston-McPherson GN, Stapleton DS, Keller MP, Attie AD, Smith KA, Tang W. From methylene bridged diindole to carbonyl linked benzimidazoleindole: Development of potent and metabolically stable PCSK9 modulators. European Journal of Medicinal Chemistry. 206: 112678. PMID 32823006 DOI: 10.1016/J.Ejmech.2020.112678 |
0.557 |
|
| 2020 |
Yang K, Zhao Y, Nie X, Wu H, Wang B, Almodovar-Rivera CM, Xie H, Tang W. A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders. Cell Chemical Biology. PMID 32413286 DOI: 10.1016/J.Chembiol.2020.04.008 |
0.603 |
|
| 2019 |
Wu H, Yang K, Zhang Z, Leisten E, Li Z, Xie H, Liu J, Smith KA, Novakova Z, Barinka C, Tang W. Development of Multi-Functional Histone Deacetylase 6 Degraders with Potent Anti-Myeloma Activity. Journal of Medicinal Chemistry. PMID 31271281 DOI: 10.1021/Acs.Jmedchem.9B00516 |
0.593 |
|
| 2019 |
Winston-McPherson GN, Xie H, Yang K, Li X, Shu D, Tang W. Discovery of 2,3'-diindolylmethanes as a novel class of PCSK9 modulators. Bioorganic & Medicinal Chemistry Letters. PMID 31227343 DOI: 10.1016/J.Bmcl.2019.06.014 |
0.56 |
|
| 2019 |
Wang B, Wu S, Liu J, Yang K, Xie H, Tang W. Development of selective small molecule MDM2 degraders based on nutlin. European Journal of Medicinal Chemistry. 176: 476-491. PMID 31128449 DOI: 10.1016/J.Ejmech.2019.05.046 |
0.58 |
|
| 2018 |
Yang K, Song Y, Xie H, Wu H, Wu YT, Leisten ED, Tang W. Development of the first small molecule histone deacetylase 6 (HDAC6) degraders. Bioorganic & Medicinal Chemistry Letters. PMID 29871848 DOI: 10.1016/J.Bmcl.2018.05.057 |
0.573 |
|
| 2017 |
Liu J, Simmons CJ, Xie H, Yang F, Zhao X, Tang Y, Tang W. Synthesis of Highly Substituted Benzofuran–containing Natural Products via Rh–catalyzed Carbonylative Benzannulation Advanced Synthesis & Catalysis. 359: 693-697. DOI: 10.1002/Adsc.201600992 |
0.551 |
|
| 2016 |
Li X, Xie H, Fu X, Liu J, Wang HY, Xi BM, Liu P, Xu X, Tang W. Rhodium(I)-Catalyzed Benzannulation of Heteroaryl Propargylic Esters: Synthesis of Indoles and Related Heterocycles. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27189811 DOI: 10.1002/Chem.201602088 |
0.608 |
|
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