Marco A. Marra, Ph.D. - Publications

Affiliations: 
1989-1994 Medical Genetics University of British Columbia, Vancouver, Vancouver, BC, Canada 

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Year Citation  Score
2024 Grants JM, May C, Bridgers J, Huang S, Gillis S, Meissner B, Boyle M, Ben-Neriah S, Hung S, Duns G, Hilton L, Gerrie AS, Marra M, Kridel R, Sabatini PJB, et al. Chronic Lymphocytic Leukemia IGHV Somatic Hypermutation Detection by Targeted Capture Next-Generation Sequencing. Clinical Chemistry. 70: 273-284. PMID 38175592 DOI: 10.1093/clinchem/hvad147  0.699
2023 Hilton LK, Ngu HS, Collinge B, Dreval K, Ben-Neriah S, Rushton CK, Wong JCH, Cruz M, Roth A, Boyle M, Meissner B, Slack GW, Farinha P, Craig JW, Gerrie AS, ... ... Marra MA, et al. Relapse Timing Is Associated With Distinct Evolutionary Dynamics in Diffuse Large B-Cell Lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2300570. PMID 37319384 DOI: 10.1200/JCO.23.00570  0.791
2023 Dreval K, Hilton LK, Cruz M, Shaalan H, Ben-Neriah S, Boyle M, Collinge BJ, Coyle KM, Duns G, Farinha P, Grande B, Meissner B, Pararajalingam P, Rushton CK, Slack GW, ... ... Marra MA, et al. Genetic Subdivisions of Follicular Lymphoma Defined by Distinct Coding and non-coding Mutation Patterns. Blood. PMID 37084389 DOI: 10.1182/blood.2022018719  0.805
2023 Tsang ES, Csizmok V, Williamson LM, Pleasance E, Topham JT, Karasinska JM, Titmuss E, Schrader I, Yip S, Tessier-Cloutier B, Mungall K, Ng T, Sun S, Lim HJ, Loree JM, ... ... Marra MA, et al. Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration. Npj Precision Oncology. 7: 31. PMID 36964191 DOI: 10.1038/s41698-023-00368-x  0.308
2023 Hilton LK, Ngu HS, Collinge B, Dreval K, Ben-Neriah S, Rushton CK, Wong JCH, Cruz M, Roth A, Boyle M, Meissner B, Slack GW, Farinha P, Craig JW, Gerrie AS, ... ... Marra MA, et al. Relapse timing is associated with distinct evolutionary dynamics in DLBCL. Medrxiv : the Preprint Server For Health Sciences. PMID 36945587 DOI: 10.1101/2023.03.06.23286584  0.824
2022 Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudière-Morrison L, Mercier AL, Shokouhian M, Suárez RA, Ly M, Borlase S, Scott DS, ... ... Marra MA, et al. Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. PMID 36446943 DOI: 10.1038/s41586-022-05578-0  0.397
2022 Topham JT, Tsang ES, Karasinska JM, Metcalfe A, Ali H, Kalloger SE, Csizmok V, Williamson LM, Titmuss E, Nielsen K, Negri GL, Spencer Miko SE, Jang GH, Denroche RE, Wong HL, ... ... Marra MA, et al. Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma. Nature Communications. 13: 5941. PMID 36209277 DOI: 10.1038/s41467-022-33718-7  0.342
2022 Thomas N, Dreval K, Gerhard DS, Hilton LK, Abramson JS, Barta SK, Bartlett NL, Bethony J, Bhatia K, Bowen J, Bryan AC, Cesarman E, Casper C, Cruz M, Dyer M, ... ... Marra MA, et al. GENETIC SUBGROUPS INFORM ON PATHOBIOLOGY IN ADULT AND PEDIATRIC BURKITT LYMPHOMA. Blood. PMID 36201743 DOI: 10.1182/blood.2022016534  0.821
2022 Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudière-Morrison L, Mercier AL, Shokouhian M, Suárez RA, Ly M, Borlase S, Scott DS, ... ... Marra MA, et al. Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. PMID 36131014 DOI: 10.1038/s41586-022-05215-w  0.504
2022 Titmuss E, Corbett RD, Davidson S, Abbasi S, Williamson LM, Pleasance ED, Shlien A, Renouf DJ, Jones SJM, Laskin J, Marra MA. TMBur: a distributable tumor mutation burden approach for whole genome sequencing. Bmc Medical Genomics. 15: 190. PMID 36071521 DOI: 10.1186/s12920-022-01348-z  0.348
2022 Dodani DD, Nguyen MH, Morin RD, Marra MA, Corbett RD. Combinatorial and Machine Learning Approaches for Improved Somatic Variant Calling From Formalin-Fixed Paraffin-Embedded Genome Sequence Data. Frontiers in Genetics. 13: 834764. PMID 35571031 DOI: 10.3389/fgene.2022.834764  0.547
2022 Lavoie JM, Csizmok V, Williamson LM, Culibrk L, Wang G, Marra MA, Laskin J, Jones SJM, Renouf DJ, Kollmannsberger CK. Whole-genome and transcriptome analysis of advanced adrenocortical cancer highlights multiple alterations affecting epigenome and DNA repair pathways. Cold Spring Harbor Molecular Case Studies. 8. PMID 35483882 DOI: 10.1101/mcs.a006148  0.408
2021 Richards LM, Whitley OKN, MacLeod G, Cavalli FMG, Coutinho FJ, Jaramillo JE, Svergun N, Riverin M, Croucher DC, Kushida M, Yu K, Guilhamon P, Rastegar N, Ahmadi M, Bhatti JK, ... ... Marra MA, et al. Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity. Nature Cancer. 2: 157-173. PMID 35122077 DOI: 10.1038/s43018-020-00154-9  0.808
2021 Zhang Y, Chen F, Pleasance E, Williamson L, Grisdale CJ, Titmuss E, Laskin J, Jones SJM, Cortes-Ciriano I, Marra MA, Creighton CJ. Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy. Cell Reports. 37: 110023. PMID 34788622 DOI: 10.1016/j.celrep.2021.110023  0.306
2021 Yang KC, Kalloger SE, Aird JJ, Lee MKC, Rushton C, Mungall KL, Mungall AJ, Gao D, Chow C, Xu J, Karasinska JM, Colborne S, Jones SJM, Schrader J, Morin RD, ... ... Marra MA, et al. Proteotranscriptomic classification and characterization of pancreatic neuroendocrine neoplasms. Cell Reports. 37: 109817. PMID 34644566 DOI: 10.1016/j.celrep.2021.109817  0.807
2021 Salehi S, Kabeer F, Ceglia N, Andronescu M, Williams MJ, Campbell KR, Masud T, Wang B, Biele J, Brimhall J, Gee D, Lee H, Ting J, Zhang AW, Tran H, ... ... Marra MA, et al. Clonal fitness inferred from time-series modelling of single-cell cancer genomes. Nature. PMID 34163070 DOI: 10.1038/s41586-021-03648-3  0.302
2021 Skowron P, Farooq H, Cavalli FMG, Morrissy AS, Ly M, Hendrikse LD, Wang EY, Djambazian H, Zhu H, Mungall KL, Trinh QM, Zheng T, Dai S, Stucklin ASG, Vladoiu MC, ... ... Marra MA, et al. The transcriptional landscape of Shh medulloblastoma. Nature Communications. 12: 1749. PMID 33741928 DOI: 10.1038/s41467-021-21883-0  0.303
2021 Richards LM, Whitley OKN, MacLeod G, Cavalli FMG, Coutinho FJ, Jaramillo JE, Svergun N, Riverin M, Croucher DC, Kushida M, Yu K, Guilhamon P, Rastegar N, Ahmadi M, Bhatti JK, ... ... Marra MA, et al. Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity Nature Cancer. 2: 157-173. DOI: 10.1038/s43018-020-00154-9  0.403
2020 Pleasance E, Titmuss E, Williamson L, Kwan H, Culibrk L, Zhao EY, Dixon K, Fan K, Bowlby R, Jones MR, Shen Y, Grewal JK, Ashkani J, Wee K, Grisdale CJ, ... ... Marra MA, et al. Pan-cancer analysis of advanced patient tumors reveals interactions between therapy and genomic landscapes. Nature Cancer. 1: 452-468. PMID 35121966 DOI: 10.1038/s43018-020-0050-6  0.347
2020 Tsang ES, Grisdale CJ, Pleasance ED, Topham JT, Mungall KL, Reisle CR, Choo C, Carreira M, Bowlby R, Karasinska JM, MacMillan D, Williamson LM, Chuah E, Moore RA, Mungall AJ, ... ... Marra MA, et al. Uncovering Clinically Relevant Gene Fusions with Integrated Genomic and Transcriptomic Profiling of Metastatic Cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33148671 DOI: 10.1158/1078-0432.CCR-20-1900  0.305
2020 Dixon K, Young S, Shen Y, Thibodeau ML, Fok A, Pleasance E, Zhao E, Jones M, Aubert G, Armstrong L, Virani A, Regier D, Gelmon K, Renouf D, Chia S, ... ... Marra M, et al. Establishing a Framework for the Clinical Translation of Germline Findings in Precision Oncology. Jnci Cancer Spectrum. 4: pkaa045. PMID 33134827 DOI: 10.1093/Jncics/Pkaa045  0.736
2020 Collinge BJ, Ben-Neriah S, Chong LC, Boyle M, Jiang A, Miyata-Takata T, Farinha P, Craig JW, Slack GW, Ennishi D, Mottok A, Meissner B, Chavez EA, Gerrie AS, Villa D, ... ... Marra MA, et al. Impact of MYC and BCL2 structural variants in tumors of DLBCL morphology and mechanisms of false-negative MYC IHC. Blood. PMID 33120427 DOI: 10.1182/blood.2020007193  0.566
2020 Guenter J, Abadi S, Lim H, Chia S, Woods R, Jones M, Rebic N, Renouf DJ, Laskin J, Marra M. Evaluating genomic biomarkers associated with resistance or sensitivity to chemotherapy in patients with advanced breast and colorectal cancer. Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners. 1078155220951845. PMID 32847480 DOI: 10.1177/1078155220951845  0.356
2020 Isaev K, Ennishi D, Hilton L, Skinnider B, Mungall KL, Mungall AJ, Bakhtiari M, Tremblay-LeMay R, Silva A, Ben-Neriah S, Boyle M, Villa D, Marra MA, Steidl C, Gascoyne RD, et al. Molecular Attributes Underlying Central Nervous System and Systemic Relapse in Diffuse Large B-cell Lymphoma. Haematologica. PMID 32817292 DOI: 10.3324/Haematol.2020.255950  0.755
2020 Gagliardi A, Porter VL, Zong Z, Bowlby R, Titmuss E, Namirembe C, Griner NB, Petrello H, Bowen J, Chan SK, Culibrk L, Darragh TM, Stoler MH, Wright TC, Gesuwan P, ... ... Marra MA, et al. Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade-specific epigenome and transcriptome landscapes. Nature Genetics. 52: 800-810. PMID 32747824 DOI: 10.1038/S41588-020-0673-7  0.339
2020 Thibodeau ML, O'Neill K, Dixon K, Reisle C, Mungall KL, Krzywinski M, Shen Y, Lim HJ, Cheng D, Tse K, Wong T, Chuah E, Fok A, Sun S, Renouf D, ... ... Marra MA, et al. Improved structural variant interpretation for hereditary cancer susceptibility using long-read sequencing. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 32624572 DOI: 10.1038/S41436-020-0880-8  0.382
2020 Rushton CK, Arthur SE, Alcaide M, Cheung M, Jiang A, Coyle KM, Cleary KLS, Thomas N, Hilton LK, Michaud N, Daigle S, Davidson J, Bushell K, Yu S, Rys RN, ... ... Marra MA, et al. Genetic and evolutionary patterns of treatment resistance in relapsed B-cell lymphoma. Blood Advances. 4: 2886-2898. PMID 32589730 DOI: 10.1182/Bloodadvances.2020001696  0.804
2020 Topham JT, Titmuss E, Pleasance ED, Williamson LM, Karasinska JM, Culibrk L, Lee MK, Mendis S, Denroche RE, Jang GH, Kalloger SE, Wong HL, Moore RA, Mungall AJ, O'Kane GM, ... ... Marra MA, et al. Endogenous retrovirus transcript levels are associated with immunogenic signatures in multiple metastatic cancer types. Molecular Cancer Therapeutics. PMID 32518206 DOI: 10.1158/1535-7163.Mct-20-0094  0.387
2020 Calvente L, Tremblay-LeMay R, Xu W, Chan FC, Hong M, Zhang T, Yhim HY, Kuruvilla J, Crump M, Kukreti V, Prica A, Regier D, Marra MA, Karsan A, Steidl C, et al. Validation of the RHL30 digital gene expression assay as a prognostic biomarker for relapsed Hodgkin lymphoma. British Journal of Haematology. PMID 32510594 DOI: 10.1111/Bjh.16777  0.326
2020 Garancher A, Suzuki H, Haricharan S, Chau LQ, Masihi MB, Rusert JM, Norris PS, Carrette F, Romero MM, Morrissy SA, Skowron P, Cavalli FMG, Farooq H, Ramaswamy V, Jones SJM, ... ... Marra MA, et al. Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma. Nature Neuroscience. PMID 32424282 DOI: 10.1038/S41593-020-0628-4  0.311
2020 Pararajalingam P, Coyle KM, Arthur S, Thomas N, Alcaide M, Meissner B, Boyle M, Qureshi Q, Grande BM, Rushton C, Slack GW, Mungall A, Tam C, Agarwal R, Dawson SJ, ... ... Marra MA, et al. Coding and non-coding drivers of mantle cell lymphoma identified through exome and genome sequencing. Blood. PMID 32160292 DOI: 10.1182/Blood.2019002385  0.84
2020 Mendis S, Alcaide M, Topham JT, Johnson B, Morin RD, Chu J, Bosdet I, Kopetz S, Karsan A, Gill S, Laskin J, Jones SJM, Marra MA, Schaeffer DF, Renouf DJ, et al. Integration of Whole-Genome Sequencing With Circulating Tumor DNA Analysis Captures Clonal Evolution and Tumor Heterogeneity in Non-V600 BRAF Mutant Colorectal Cancer. Clinical Colorectal Cancer. PMID 32151517 DOI: 10.1016/J.Clcc.2020.02.001  0.812
2020 Ennishi D, Healy S, Bashashati A, Saberi S, Hother C, Mottok A, Chan FC, Chong L, Abraham L, Kridel R, Boyle M, Meissner B, Aoki T, Takata K, Woolcock BW, ... ... Marra MA, et al. TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma. Nature Medicine. PMID 32094924 DOI: 10.1038/S41591-020-0757-Z  0.819
2020 Chan-Seng-Yue M, Kim JC, Wilson GW, Ng K, Figueroa EF, O'Kane GM, Connor AA, Denroche RE, Grant RC, McLeod J, Wilson JM, Jang GH, Zhang A, Liang SB, Borgida A, ... ... Marra MA, et al. Author Correction: Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution. Nature Genetics. PMID 32051610 DOI: 10.1038/S41588-020-0588-3  0.356
2020 Chan-Seng-Yue M, Kim JC, Wilson GW, Ng K, Figueroa EF, O'Kane GM, Connor AA, Denroche RE, Grant RC, McLeod J, Wilson JM, Jang GH, Zhang A, Liang SB, Borgida A, ... ... Marra MA, et al. Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution. Nature Genetics. PMID 31932696 DOI: 10.1038/S41588-019-0566-9  0.46
2020 Lavoie JM, Mitchell T, Lee SE, Deol B, Chia SK, Gelmon KA, Kollmannsberger CK, Tinker AV, Jones SJM, Marra M, Laskin J, Renouf DJ. Patient selection for a developmental therapeutics program using whole genome and Transcriptome analysis. Investigational New Drugs. PMID 31907737 DOI: 10.1007/S10637-020-00892-8  0.358
2020 Rushton C, Alcaide M, Cheung M, Michaud NR, Daigle S, Rys RN, Arthur SE, Zrymiak M, Davidson J, Bushell KR, Yu S, Jain MD, Shepherd LE, Marra MA, Kuruvilla J, et al. The Copy Number Landscape of Relapsed and Refractory Diffuse Large B-Cell Lymphoma Blood. 136: 8-9. DOI: 10.1182/blood-2020-142871  0.563
2020 Garancher A, Suzuki H, Haricharan S, Masihi MB, Rusert JM, Norris PS, Carrette F, Romero MM, Morrissy SA, Skowron P, Cavalli FMG, Farooq H, Ramaswamy V, Morcavallo A, Henderson JJ, ... ... Marra MA, et al. Abstract IA11: Overcoming immune evasion in pediatric brain tumors Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-Ia11  0.318
2019 Laks E, McPherson A, Zahn H, Lai D, Steif A, Brimhall J, Biele J, Wang B, Masud T, Ting J, Grewal D, Nielsen C, Leung S, Bojilova V, Smith M, ... ... Marra MA, et al. Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing. Cell. 179: 1207-1221.e22. PMID 31730858 DOI: 10.1016/J.Cell.2019.10.026  0.425
2019 Chun HE, Johann PD, Milne K, Zapatka M, Buellesbach A, Ishaque N, Iskar M, Erkek S, Wei L, Tessier-Cloutier B, Lever J, Titmuss E, Topham JT, Bowlby R, Chuah E, ... ... Marra MA, et al. Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration. Cell Reports. PMID 31708418 DOI: 10.1016/J.Celrep.2019.10.013  0.427
2019 Haile S, Corbett RD, Bilobram S, Mungall K, Grande BM, Kirk H, Pandoh P, MacLeod T, McDonald H, Bala M, Coope RJ, Moore RA, Mungall AJ, Zhao Y, Morin RD, ... ... Marra MA, et al. Evaluation of protocols for rRNA depletion-based RNA sequencing of nanogram inputs of mammalian total RNA. Plos One. 14: e0224578. PMID 31671154 DOI: 10.1371/Journal.Pone.0224578  0.767
2019 Suzuki H, Kumar SA, Shuai S, Diaz-Navarro A, Gutierrez-Fernandez A, De Antonellis P, Cavalli FMG, Juraschka K, Farooq H, Shibahara I, Vladoiu MC, Zhang J, Abeysundara N, Przelicki D, Skowron P, ... ... Marra MA, et al. Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma. Nature. 574: 707-711. PMID 31664194 DOI: 10.1038/S41586-019-1650-0  0.415
2019 Suzuki H, Kumar SA, Shuai S, Diaz-Navarro A, Gutierrez-Fernandez A, De Antonellis P, Cavalli FMG, Juraschka K, Farooq H, Shibahara I, Vladoiu MC, Zhang J, Abeysundara N, Przelicki D, Skowron P, ... ... Marra MA, et al. Recurrent non-coding U1-snRNA mutations drive cryptic splicing in Shh medulloblastoma. Nature. PMID 31597162 DOI: 10.1038/s41586-019-1650-0  0.3
2019 Karasinska JM, Topham JT, Kalloger S, Jang GH, Denroche RE, Culibrk L, Williamson LM, Wong HL, Lee MK, O'Kane GM, Moore RA, Mungall AJ, Moore MJ, Warren C, Metcalfe A, ... ... Marra MA, et al. Altered gene expression along the glycolysis-cholesterol synthesis axis is associated with outcome in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31481506 DOI: 10.1158/1078-0432.Ccr-19-1543  0.311
2019 Shen Y, Grisdale CJ, Islam SA, Bose P, Lever J, Zhao EY, Grinshtein N, Ma Y, Mungall AJ, Moore RA, Lun X, Senger DL, Robbins SM, Wang AY, MacIsaac JL, ... ... Marra MA, et al. Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments. Proceedings of the National Academy of Sciences of the United States of America. PMID 31471491 DOI: 10.1073/Pnas.1813495116  0.413
2019 Mottok A, Hung SS, Chavez EA, Woolcock B, Telenius A, Chong LC, Meissner B, Nakamura H, Rushton C, Viganò E, Sarkozy C, Gascoyne RD, Connors JM, Ben Neriah S, Mungall A, ... Marra MA, et al. Integrative genomic analysis identifies key pathogenic mechanisms in primary mediastinal large B-cell lymphoma. Blood. PMID 31292115 DOI: 10.1182/Blood.2019001126  0.823
2019 Johnston M, Nikolic A, Ninkovic N, Guilhamon P, Cavalli F, Seaman S, Zemp F, Lee J, Abdelkareem A, Ellestad K, Murison A, Kushida M, Coutinho F, Ma Y, Mungall A, ... ... Marra M, et al. High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma. Genome Research. PMID 31249064 DOI: 10.1101/Gr.246520.118  0.598
2019 Kwan HH, Culibrk L, Taylor GA, Leelakumari S, Tan R, Jackman SD, Tse K, MacLeod T, Cheng D, Chuah E, Kirk H, Pandoh P, Carlsen R, Zhao Y, Mungall AJ, ... ... Marra MA, et al. The Genome of the Steller Sea Lion (). Genes. 10. PMID 31248052 DOI: 10.3390/Genes10070486  0.392
2019 Negri GL, Grande BM, Delaidelli A, El-Naggar A, Cochrane D, Lau CC, Triche TJ, Moore RA, Jones SJM, Montpetit A, Marra MA, Malkin D, Morin RD, Sorensen PH. Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma. The Journal of Pathology. PMID 31236944 DOI: 10.1002/Path.5319  0.83
2019 Williamson LM, Steel M, Grewal JK, Thibodeau ML, Zhao EY, Loree JM, Yang KC, Gorski SM, Mungall AJ, Mungall KL, Moore RA, Marra MA, Laskin J, Renouf DJ, Schaeffer DF, et al. Genomic characterization of a well-differentiated grade 3 pancreatic neuroendocrine tumor. Cold Spring Harbor Molecular Case Studies. 5. PMID 31160355 DOI: 10.1101/mcs.a003814  0.349
2019 Jones MR, Williamson LM, Topham JT, Lee MK, Goytain A, Ho J, Denroche RE, Jang GH, Pleasance ED, Shen Y, Karasinska JM, McGhie JP, Gill S, Lim H, Moore MJ, ... ... Marra MA, et al. NRG1 gene fusions are recurrent, clinically actionable gene rearrangements in KRAS wild-type pancreatic ductal adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31068372 DOI: 10.1158/1078-0432.Ccr-19-0191  0.321
2019 Vladoiu MC, El-Hamamy I, Donovan LK, Farooq H, Holgado BL, Sundaravadanam Y, Ramaswamy V, Hendrikse LD, Kumar S, Mack SC, Lee JJY, Fong V, Juraschka K, Przelicki D, Michealraj A, ... ... Marra MA, et al. Childhood cerebellar tumours mirror conserved fetal transcriptional programs. Nature. PMID 31043743 DOI: 10.1038/S41586-019-1158-7  0.528
2019 Ahmad ST, Rogers AD, Chen MJ, Dixit R, Adnani L, Frankiw LS, Lawn SO, Blough MD, Alshehri M, Wu W, Marra MA, Robbins SM, Cairncross JG, Schuurmans C, Chan JA. Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors. Nature Communications. 10: 2000. PMID 31043608 DOI: 10.1038/S41467-019-09949-6  0.323
2019 Hoffman M, Gillmor A, Kunz DJ, Johnston MJ, Nikolic A, Narta K, Zarrei M, King JC, Ellestad K, Dang NH, Cavalli FMG, Kushida M, Coutinho FJ, Zhu Y, Luu B, ... ... Marra MA, et al. Intratumoral genetic and functional heterogeneity in pediatric glioblastoma. Cancer Research. PMID 30877103 DOI: 10.1158/0008-5472.Can-18-3441  0.621
2019 Pandoh PK, Corbett RD, McDonald H, Alcaide M, Kirk H, Trinh E, Haile S, MacLeod T, Smailus D, Bilobram S, Mungall AJ, Ma Y, Moore RA, Coope R, Zhao Y, ... ... Marra MA, et al. A high-throughput protocol for isolating cell-free circulating tumor DNA from peripheral blood. Biotechniques. 66: 85-92. PMID 30744412 DOI: 10.2144/Btn-2018-0148  0.762
2019 Ennishi D, Takata K, Beguelin W, Duns G, Mottok A, Farinha P, Bashashati A, Saberi S, Boyle M, Meissner B, Ben-Neriah S, Woolcock BW, Telenius A, Lai D, Teater M, ... ... Marra MA, et al. Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition. Cancer Discovery. PMID 30705065 DOI: 10.1158/2159-8290.Cd-18-1090  0.636
2019 Grande BM, Gerhard DS, Jiang A, Griner NB, Abramson JS, Alexander TB, Allen H, Ayers LW, Bethony JM, Bhatia K, Bowen J, Casper C, Choi JK, Culibrk L, Davidsen TM, ... ... Marra MA, et al. Genome-wide discovery of somatic coding and non-coding mutations in pediatric endemic and sporadic Burkitt lymphoma. Blood. PMID 30617194 DOI: 10.1182/Blood-2018-09-871418  0.835
2019 Lee M, Jones MR, Williamson L, Topham JT, Addison S, Wong H, Denroche R, Jang GH, Karasinska J, McGhie JP, Gill S, Lim HJ, Yip S, Knox JJ, Gallinger S, ... ... Marra MA, et al. Comprehensive genomic analysis of metastatic pancreatic ductal adenocarcinoma (mPDAC) reveals a significant proportion of clinical actionable aberrations. Journal of Clinical Oncology. 37: 273-273. DOI: 10.1200/Jco.2019.37.4_Suppl.273  0.432
2019 Lavoie J, Csizmok V, Wang G, Williamson L, Marra MA, Laskin JJ, Jones SJM, Renouf DJ, Kollmannsberger CK. Whole genome and transcriptome analysis (WGTA) of metastatic adrenocortical carcinoma (mACC). Journal of Clinical Oncology. 37: e16123-e16123. DOI: 10.1200/Jco.2019.37.15_Suppl.E16123  0.466
2019 Mendis SR, Topham JT, Titmuss E, Williamson L, Pleasance ED, Culibrk L, Karasinska J, Liu SL, Lee M, Aird J, Moore RA, Mungall AJ, Laskin JJ, Jones SJM, Marra MA, et al. Comprehensive transcriptome analysis reveals link between epigenetic dysregulation, endogenous retrovirus expression and immunogenicity in metastatic colorectal carcinoma. Journal of Clinical Oncology. 37: 3535-3535. DOI: 10.1200/Jco.2019.37.15_Suppl.3535  0.4
2019 Zhao EY, Feng X, Pleasance ED, Ng TL, Grewal J, Mohammad N, Taylor SK, Simmons CE, Srikanthan A, Rassekh SR, Deyell R, Shen Y, Titmuss E, Lim HJ, Renouf DJ, ... ... Marra MA, et al. The whole genome landscape of adult metastatic sarcoma. Journal of Clinical Oncology. 37: 3137-3137. DOI: 10.1200/Jco.2019.37.15_Suppl.3137  0.374
2019 LeVasseur N, Csizmok V, Bonakdar M, Shen Y, Zibrik L, Zhao EY, Sun S, Gelmon KA, Laskin JJ, Marra MA, Chia SKL. Whole transcriptome sequencing in metastatic cancer: A review of expression outliers in 113 metastatic breast cancer patients. Journal of Clinical Oncology. 37: 3080-3080. DOI: 10.1200/Jco.2019.37.15_Suppl.3080  0.389
2019 Wei L, Ries RE, Plettner P, Mungall K, Mungall AJ, Meshinchi S, Marra MA. Transcriptome Analysis of Pediatric AML Reveals Non Protein-Coding RNAs Associated with Poor Survival Outcome and Treatment Resistance Blood. 134: 2675-2675. DOI: 10.1182/Blood-2019-132008  0.36
2019 Coyle KM, Pararajalingam P, Arthur SE, Thomas N, Alcaide M, Meissner B, Boyle M, Grande BM, Rushton C, Tooman L, Slack GW, Mungall AJ, Gascoyne RD, Steidl C, Connors JM, ... ... Marra MA, et al. Mutations Affecting RNA Binding Proteins Are a Novel Feature of Mantle Cell Lymphoma Blood. 134: 1478-1478. DOI: 10.1182/Blood-2019-129136  0.831
2019 Kridel R, Isaev K, Ennishi D, Skinnider B, Mungall K, Mungall AJ, Bakhtiari M, Tremblay-Lemay R, Meissner B, Ben-Neriah S, Boyle M, Villa D, Marra MA, Steidl C, Gascoyne RD, et al. Molecular Correlates of Central Nervous System Relapse in Diffuse Large B-Cell Lymphoma Blood. 134: 2763-2763. DOI: 10.1182/Blood-2019-124235  0.452
2019 Farinha P, Ennishi D, Mottok A, Ben-Neriah S, Meissner B, Boyle M, Craig JW, Slack GW, Villa D, Savage KJ, Sehn LH, Morin RD, Marra MA, Connors JM, Gascoyne RD, et al. TP53 Expression Correlates with TP53 Mutations and Is an Independent Predictor of Clinical Outcome in Patients with DLBCL Treated with R-CHOP Blood. 134: 3964-3964. DOI: 10.1182/Blood-2019-121943  0.631
2019 Tsang ES, Topham JT, Karasinska JM, Lee MKC, Mendis S, Culibrk L, Denroche R, Jang GH, Kalloger SE, Moore RA, Mungall AJ, Laskin J, O'Kane GM, Knox JJ, Gallinger S, ... ... Marra MA, et al. Abstract B57: Early-onset pancreatic ductal adenocarcinomas are characterized by a distinct mutational landscape Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-B57  0.403
2019 Topham JT, Titmuss E, Pleasance E, Williamson LM, Karasinska JM, Culibrk L, Lee MKC, Kalloger SE, Mendis S, Moore RA, Mungall AJ, Laskin J, Loree JM, Mager DL, Marra MA, et al. Abstract B56: Endogenous retrovirus transcript levels are associated with immunogenic signatures in multiple metastatic cancer types Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-B56  0.376
2019 Karasinska JM, Topham JT, Kalloger SE, Jang GH, Denroche RE, Culibrk L, Williamson LM, Wong H, Lee MKC, O'Kane GM, Moore RA, Mungall AJ, Moore MJ, Warren C, Metcalfe A, ... ... Marra MA, et al. Abstract A24: Gene expression along the glycolysis-cholesterol synthesis axis and outcome in pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A24  0.372
2019 Healy S, Ennishi D, Bashashati A, Saberi S, Hother C, Mottok A, Chan FC, Chong L, Kridel R, Boyle M, Meissner B, Aoki T, Takata K, Woolcock BW, Vigano E, ... ... Marra MA, et al. Abstract 3480:TMEM30Aloss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma Cancer Research. 79: 3480-3480. DOI: 10.1158/1538-7445.Am2019-3480  0.64
2019 Johann P, Chun H, Erkek S, Iskar M, Perlman E, Hasselblatt M, Pfister SM, Marra M, Kool M. Atrt-09. Integrative Analyses Of Gene Regulatory Landscapes Reveal Rhabdoid Tumor Subgroups With Possible Immune Modulation Through Epigenetic Dysregulation Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz036.008  0.312
2019 Pender A, Titmuss E, Pleasance E, Fan K, Pearson H, Bonakdar M, Taylor G, Mungall K, Moore R, Lavoie J-, Yip S, Lim H, Renouf D, Jones SJ, Marra MA, et al. Predictive markers of checkpoint inhibitor activity in adult metastatic solid tumours Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz253.081  0.312
2019 Arthur SE, Mottok A, Cojocaru R, Jiang A, Grande BM, Alcaide M, Rushton C, Ennishi D, Lat PK, Davidson J, Bushell KR, Audas T, Unrau P, Sen D, Gascoyne RD, ... Marra MA, et al. Functional Characterization Of Nfkbiz 3′ Utr Mutations In Diffuse Large B-Cell Lymphoma Hematological Oncology. 37: 74-75. DOI: 10.1002/Hon.43_2629  0.796
2019 Mottok A, Hung S, Chavez E, Woolcock B, Telenius A, Chong L, Meissner B, Nakamura H, Gascoyne R, Connors J, Ben Neriah S, Mungall A, Marra M, Siebert R, Scott D, et al. INTEGRATIVE GENOMIC ANALYSIS IDENTIFIES KEY PATHOGENIC CONCEPTS IN PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA Hematological Oncology. 37: 156-156. DOI: 10.1002/Hon.112_2629  0.395
2018 Wong HL, Zhao EY, Jones MR, Reisle CR, Eirew P, Pleasance E, Grande BM, Karasinska JM, Kalloger SE, Lim HJ, Shen Y, Yip S, Morin RD, Laskin J, Marra MA, et al. Temporal Dynamics of Genomic Alterations in a Germline-Mutated Pancreatic Cancer With Low Genomic Instability Burden but Exceptional Response to Fluorouracil, Oxaliplatin, Leucovorin, and Irinotecan. Jco Precision Oncology. 2. PMID 32913994 DOI: 10.1200/PO.18.00057  0.796
2018 Liu SL, Loree J, Renouf D, Jones M, Yip S, Marra M, Jones S, Nelson J, Laskin J, Lim H, Gill S. Clinical benefit of whole genome and transcriptome analysis (WGTA) in metastatic colorectal cancer (MCRC): Results from the personalized oncogenomics program (POG). Annals of Oncology : Official Journal of the European Society For Medical Oncology. 29: viii195. PMID 32136392 DOI: 10.1093/Annonc/Mdy281.131  0.328
2018 Newton Y, Rassekh SR, Deyell RJ, Shen Y, Jones MR, Dunham C, Yip S, Leelakumari S, Zhu J, McColl D, Swatloski T, Salama SR, Ng T, Hendson G, Lee AF, ... ... Marra MA, et al. Comparative RNA-Sequencing Analysis Benefits a Pediatric Patient With Relapsed Cancer. Jco Precision Oncology. 2. PMID 31372595 DOI: 10.1200/PO.17.00198  0.736
2018 Ennishi D, Jiang A, Boyle M, Collinge B, Grande BM, Ben-Neriah S, Rushton C, Tang J, Thomas N, Slack GW, Farinha P, Takata K, Miyata-Takata T, Craig J, Mottok A, ... ... Marra MA, et al. Double-Hit Gene Expression Signature Defines a Distinct Subgroup of Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1801583. PMID 30523716 DOI: 10.1200/Jco.18.01583  0.796
2018 Tsang ES, Shen Y, Chooback N, Ho C, Jones M, Renouf DJ, Lim H, Sun S, Yip S, Pleasance E, Ionescu DN, Mungall K, Kasaian K, Ma Y, Zhao Y, ... ... Marra M, et al. Clinical Outcomes after Whole Genome Sequencing in Patients with Metastatic Non-Small Cell Lung Cancer. Cold Spring Harbor Molecular Case Studies. PMID 30514790 DOI: 10.1101/mcs.a002659  0.38
2018 Taylor GA, Kirk H, Coombe L, Jackman SD, Chu J, Tse K, Cheng D, Chuah E, Pandoh P, Carlsen R, Zhao Y, Mungall AJ, Moore R, Birol I, Franke M, ... Marra MA, et al. The Genome of the North American Brown Bear or Grizzly: Ursus arctos ssp. horribilis. Genes. 9. PMID 30513700 DOI: 10.3390/Genes9120598  0.407
2018 Haile S, Corbett RD, Bilobram S, Bye MH, Kirk H, Pandoh P, Trinh E, MacLeod T, McDonald H, Bala M, Miller D, Novik K, Coope RJ, Moore RA, Zhao Y, ... ... Marra MA, et al. Sources of erroneous sequences and artifact chimeric reads in next generation sequencing of genomic DNA from formalin-fixed paraffin-embedded samples. Nucleic Acids Research. PMID 30418619 DOI: 10.1093/Nar/Gky1142  0.388
2018 Chong LC, Ben-Neriah S, Slack GW, Freeman C, Ennishi D, Mottok A, Collinge B, Abrisqueta P, Farinha P, Boyle M, Meissner B, Kridel R, Gerrie AS, Villa D, Savage KJ, ... ... Marra MA, et al. High-resolution architecture and partner genes of rearrangements in lymphoma with DLBCL morphology. Blood Advances. 2: 2755-2765. PMID 30348671 DOI: 10.1182/Bloodadvances.2018023572  0.62
2018 Arthur SE, Jiang A, Grande BM, Alcaide M, Cojocaru R, Rushton CK, Mottok A, Hilton LK, Lat PK, Zhao EY, Culibrk L, Ennishi D, Jessa S, Chong L, Thomas N, ... ... Marra MA, et al. Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma. Nature Communications. 9: 4001. PMID 30275490 DOI: 10.1038/S41467-018-06354-3  0.818
2018 Alexander TB, Gu Z, Iacobucci I, Dickerson K, Choi JK, Xu B, Payne-Turner D, Yoshihara H, Loh ML, Horan J, Buldini B, Basso G, Elitzur S, de Haas V, Zwaan CM, ... ... Marra MA, et al. The genetic basis and cell of origin of mixed phenotype acute leukaemia. Nature. PMID 30209392 DOI: 10.1038/S41586-018-0436-0  0.335
2018 Wong D, Lounsbury K, Lum A, Song J, Chan S, LeBlanc V, Chittaranjan S, Marra M, Yip S. Transcriptomic analysis of CIC and ATXN1L reveal a functional relationship exploited by cancer. Oncogene. PMID 30093628 DOI: 10.1038/S41388-018-0427-5  0.363
2018 Thibodeau ML, Bonakdar M, Zhao E, Mungall KL, Reisle C, Zhang W, Bye MH, Thiessen N, Bleile D, Mungall AJ, Ma YP, Jones MR, Renouf DJ, Lim HJ, Yip S, ... ... Marra MA, et al. Whole genome and whole transcriptome genomic profiling of a metastatic eccrine porocarcinoma. Npj Precision Oncology. 2: 8. PMID 29872726 DOI: 10.1038/s41698-018-0050-5  0.37
2018 Waszak SM, Northcott PA, Buchhalter I, Robinson GW, Sutter C, Groebner S, Grund KB, Brugières L, Jones DTW, Pajtler KW, Morrissy AS, Kool M, Sturm D, Chavez L, Ernst A, ... ... Marra M, et al. Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort. The Lancet. Oncology. PMID 29753700 DOI: 10.1016/S1470-2045(18)30242-0  0.301
2018 Chahal M, Pleasance E, Grewal J, Zhao E, Ng T, Chapman E, Jones MR, Shen Y, Mungall KL, Bonakdar M, Taylor GA, Ma Y, Mungall AJ, Moore RA, Lim H, ... ... Marra MA, et al. Personalized oncogenomic analysis of metastatic adenoid cystic carcinoma: using whole-genome sequencing to inform clinical decision-making. Cold Spring Harbor Molecular Case Studies. 4. PMID 29610392 DOI: 10.1101/mcs.a002626  0.365
2018 Merk DJ, Ohli J, Merk ND, Thatikonda V, Morrissy S, Schoof M, Schmid SN, Harrison L, Filser S, Ahlfeld J, Erkek S, Raithatha K, Andreska T, Weißhaar M, Launspach M, ... ... Marra MA, et al. Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma. Developmental Cell. PMID 29551561 DOI: 10.1016/J.Devcel.2018.02.012  0.363
2018 Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, ... ... Marra MA, et al. A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases. Cell. 172: 1050-1062.e14. PMID 29474906 DOI: 10.1016/J.Cell.2018.01.038  0.31
2018 Hung SS, Meissner B, Chavez EA, Ben-Neriah S, Ennishi D, Jones MR, Shulha HP, Chan FC, Boyle M, Kridel R, Gascoyne RD, Mungall AJ, Marra MA, Scott DW, Connors JM, et al. Assessment of Capture and Amplicon-Based Approaches for the Development of a Targeted Next-Generation Sequencing Pipeline to Personalize Lymphoma Management. The Journal of Molecular Diagnostics : Jmd. PMID 29429887 DOI: 10.1016/J.Jmoldx.2017.11.010  0.498
2018 LeVasseur N, Shen Y, Zhao EY, Sun S, Laskin JJ, Gelmon KA, Marra MA, Chia SKL. Whole genome sequencing in metastatic breast cancer: Lessons learned from the BC Cancer personalized oncogenomics program. Journal of Clinical Oncology. 36: 12065-12065. DOI: 10.1200/Jco.2018.36.15_Suppl.12065  0.336
2018 Zhao EY, Pleasance ED, Jones MR, Shen Y, Reisle CR, Mungall AJ, Moore R, Zhao Y, Renouf DJ, Laskin JJ, Marra MA, Jones SJM. Evolution of genomic instability in metastatic cancer. Journal of Clinical Oncology. 36: 12008-12008. DOI: 10.1200/Jco.2018.36.15_Suppl.12008  0.423
2018 Ennishi D, Jiang A, Boyle M, Collinge B, Grande BM, Ben-Neriah S, Slack GW, Farinha P, Villa D, Mottok A, Meissner B, Saberi S, Bashashati A, Savage KJ, Sehn LH, ... ... Marra MA, et al. The Double-Hit Gene Expression Signature Defines a Clinically and Biologically Distinct Subgroup within GCB-DLBCL Blood. 132: 921-921. DOI: 10.1182/Blood-2018-99-116827  0.805
2018 Ennishi D, Takata K, Béguelin W, Duns G, Mottok A, Farinha P, Bashashati A, Scott D, Boyle M, Meissner B, Ben-Neriah S, Woolcock BW, Telenius A, Lai D, Teater MR, ... ... Marra MA, et al. Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 As a Therapeutic Target for Restoring MHC Expression in Diffuse Large B-Cell Lymphoma Blood. 132: 1560-1560. DOI: 10.1182/Blood-2018-99-112010  0.61
2018 Pearson H, Williamson L, Pleasance E, Brown S, Titmuss E, Jones M, Zong S, Sipahimalani P, Ma Y, Jones S, Holt R, Marra M, Laskin J. Abstract 4346: Integrated whole genome profiling of the immune tumour interaction identifies predictive biomarkers of checkpoint inhibitor response in metastatic cancer Cancer Research. 78: 4346-4346. DOI: 10.1158/1538-7445.Am2018-4346  0.402
2018 Lim HJ, Schrader KA, Young S, Nelson JMT, Fok A, Pleasance E, Jones M, Shen Y, Armstrong L, Virani A, Rassekh S, Deyell R, Yip S, Roscoe R, Karsan A, ... Marra M, et al. Abstract A190: Management of germline findings revealed throughout the course of tumor-normal whole genome sequencing in oncology Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-A190  0.417
2018 Shen Y, Jones MR, Pleasance E, Bonakdar M, Ch'ng C, Reisle C, Williamson L, Majounie E, Taylor G, Chan S, Pierce B, Zhang W, Muhammadzadeh A, Zhao EY, Bleile D, ... ... Marra MA, et al. Abstract A184: Clinical application of whole genome and transcriptome sequencing in cancer care Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-A184  0.451
2018 Johann P, Chun E, Erkek S, Iskar M, Perlman E, Hasselblatt M, Pfister SM, Marra M, Kool M. Atrt-09. Whole Genome And Epigenome Characterization Links Atrt-Myc To A Subgroup Of Renal Rhabdoid Tumors Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.008  0.332
2018 LeBlanc V, Trinh D, Hughes M, Luthra I, Livingstone D, Blough M, Cairncross J, Kelly J, Marra M. 1450-1545 Young Investigator Awards & Presentations Basic/Translational Exploring cellular subpopulations in glioblastoma and matched organoids using single-cell RNA-seq 52 Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 45: S13-S14. DOI: 10.1017/Cjn.2018.297  0.376
2017 Zhao EY, Shen Y, Pleasance E, Kasaian K, Leelakumari S, Jones M, Bose P, Ch'ng C, Reisle C, Eirew P, Corbett R, Mungall KL, Thiessen N, Ma Y, Schein JE, ... ... Marra MA, et al. Homologous Recombination Deficiency and Platinum-Based Therapy Outcomes in Advanced Breast Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: 7521-7530. PMID 29246904 DOI: 10.1158/1078-0432.Ccr-17-1941  0.725
2017 Jones SJM, Taylor GA, Chan S, Warren RL, Hammond SA, Bilobram S, Mordecai G, Suttle CA, Miller KM, Schulze A, Chan AM, Jones SJ, Tse K, Li I, Cheung D, ... ... Marra M, et al. The Genome of the Beluga Whale (Delphinapterus leucas). Genes. 8. PMID 29232881 DOI: 10.3390/Genes8120378  0.357
2017 Jones SJ, Haulena M, Taylor GA, Chan S, Bilobram S, Warren RL, Hammond SA, Mungall KL, Choo C, Kirk H, Pandoh P, Ally A, Dhalla N, Tam AKY, Troussard A, ... ... Marra M, et al. The Genome of the Northern Sea Otter (Enhydra lutris kenyoni). Genes. 8. PMID 29232880 DOI: 10.3390/Genes8120379  0.381
2017 Bolouri H, Farrar JE, Triche T, Ries RE, Lim EL, Alonzo TA, Ma Y, Moore R, Mungall AJ, Marra MA, Zhang J, Ma X, Liu Y, Liu Y, Auvil JMG, et al. The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions. Nature Medicine. PMID 29227476 DOI: 10.1038/Nm.4439  0.443
2017 Wong HL, Yang KC, Shen Y, Zhao EY, Loree JM, Kennecke HF, Kalloger SE, Karasinska JM, Lim HJ, Mungall AJ, Feng X, Davies JM, Schrader K, Zhou C, Karsan A, ... ... Marra MA, et al. Molecular characterisation of metastatic pancreatic neuroendocrine tumours (PNETs) using whole genome and transcriptome sequencing. Cold Spring Harbor Molecular Case Studies. PMID 29092957 DOI: 10.1101/mcs.a002329  0.36
2017 Jones MR, Lim H, Shen Y, Pleasance E, Ch'ng C, Reisle C, Leelakumari S, Zhao C, Yip S, Ho J, Zhong E, Ng T, Ionescu D, Schaeffer DF, Mungall AJ, ... ... Marra MA, et al. Successful targeting of the NRG1 pathway indicates novel treatment strategy for metastatic cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 28950338 DOI: 10.1093/Annonc/Mdx523  0.384
2017 Mazor T, Chesnelong C, Pankov A, Jalbert LE, Hong C, Hayes J, Smirnov IV, Marshall R, Souza CF, Shen Y, Viswanath P, Noushmehr H, Ronen SM, Jones SJM, Marra MA, et al. Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1. Proceedings of the National Academy of Sciences of the United States of America. PMID 28916733 DOI: 10.1073/Pnas.1708914114  0.362
2017 Bosse KR, Raman P, Zhu Z, Lane M, Martinez D, Heitzeneder S, Rathi KS, Kendsersky NM, Randall M, Donovan L, Morrissy S, Sussman RT, Zhelev DV, Feng Y, Wang Y, ... ... Marra MA, et al. Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma. Cancer Cell. 32: 295-309.e12. PMID 28898695 DOI: 10.1016/J.Ccell.2017.08.003  0.385
2017 Grewal JK, Eirew P, Jones M, Chiu K, Tessier-Cloutier B, Karnezis AN, Karsan A, Mungall A, Zhou C, Yip S, Tinker AV, Laskin J, Marra M, Jones SJM. Detection and Genomic Characterization of a mammary-like adenocarcinoma. Cold Spring Harbor Molecular Case Studies. PMID 28877932 DOI: 10.1101/mcs.a002170  0.323
2017 Gadd S, Huff V, Walz AL, Ooms AHAG, Armstrong AE, Gerhard DS, Smith MA, Auvil JMG, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Hermida LC, ... ... Marra MA, et al. A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor. Nature Genetics. PMID 28825729 DOI: 10.1038/Ng.3940  0.421
2017 Northcott PA, Buchhalter I, Morrissy AS, Hovestadt V, Weischenfeldt J, Ehrenberger T, Gröbner S, Segura-Wang M, Zichner T, Rudneva VA, Warnatz HJ, Sidiropoulos N, Phillips AH, Schumacher S, Kleinheinz K, ... ... Marra MA, et al. The whole-genome landscape of medulloblastoma subtypes. Nature. 547: 311-317. PMID 28726821 DOI: 10.1038/Nature22973  0.436
2017 Haile S, Corbett RD, MacLeod T, Bilobram S, Smailus D, Tsao P, Kirk H, McDonald H, Pandoh P, Bala M, Hirst M, Miller D, Moore RA, Mungall AJ, Schein J, ... ... Marra MA, et al. Increasing quality, throughput and speed of sample preparation for strand-specific messenger RNA sequencing. Bmc Genomics. 18: 515. PMID 28679365 DOI: 10.1186/S12864-017-3900-6  0.305
2017 Sloma I, Mitjavila-Garcia M, Feraud O, Griscelli F, Oudrhiri N, El Marsafy S, Gobbo E, Divers D, Proust A, Smadja DM, Desterke C, Carles A, Ma Y, Hirst M, Marra MA, et al. Whole genome analysis reveals unexpected dynamics of mutant subclone development in a patient with JAK2-V617F-positive chronic myeloid leukemia. Experimental Hematology. PMID 28602946 DOI: 10.1016/J.Exphem.2017.05.007  0.432
2017 Haile S, Pandoh P, McDonald H, Corbett RD, Tsao P, Kirk H, MacLeod T, Jones M, Bilobram S, Brooks D, Smailus D, Steidl C, Scott DW, Bala M, Hirst M, ... ... Marra MA, et al. Automated high throughput nucleic acid purification from formalin-fixed paraffin-embedded tissue samples for next generation sequence analysis. Plos One. 12: e0178706. PMID 28570594 DOI: 10.1371/Journal.Pone.0178706  0.317
2017 Zahir FR, Mwenifumbo JC, Chun HE, Lim EL, Van Karnebeek CDM, Couse M, Mungall KL, Lee L, Makela N, Armstrong L, Boerkoel CF, Langlois SL, McGillivray BM, Jones SJM, Friedman JM, ... Marra MA, et al. Comprehensive whole genome sequence analyses yields novel genetic and structural insights for Intellectual Disability. Bmc Genomics. 18: 403. PMID 28539120 DOI: 10.1186/S12864-017-3671-0  0.391
2017 Wang YK, Bashashati A, Anglesio MS, Cochrane DR, Grewal DS, Ha G, McPherson A, Horlings HM, Senz J, Prentice LM, Karnezis AN, Lai D, Aniba MR, Zhang AW, Shumansky K, ... ... Marra MA, et al. Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes. Nature Genetics. PMID 28436987 DOI: 10.1038/Ng.3849  0.457
2017 Morrissy AS, Cavalli FM, Remke M, Ramaswamy V, Shih DJ, Holgado BL, Farooq H, Donovan LK, Garzia L, Agnihotri S, Kiehna EN, Mercier E, Mayoh C, Papillon-Cavanagh S, Nikbakht H, ... ... Marra MA, et al. Spatial heterogeneity in medulloblastoma. Nature Genetics. PMID 28394352 DOI: 10.1038/Ng.3838  0.373
2017 Ennishi D, Mottok A, Ben-Neriah S, Shulha HP, Farinha P, Chan FC, Meissner B, Boyle M, Hother C, Kridel R, Lai D, Saberi S, Bashashati A, Shah SP, Morin RD, ... Marra MA, et al. Genetic profiling of MYC and BCL2 in diffuse large B-cell lymphoma determines cell of origin-specific clinical impact. Blood. PMID 28351934 DOI: 10.1182/Blood-2016-11-747022  0.619
2017 LeBlanc VG, Firme M, Song J, Chan SY, Lee MH, Yip S, Chittaranjan S, Marra MA. Comparative transcriptome analysis of isogenic cell line models and primary cancers links CIC loss to activation of the MAPK signalling cascade. The Journal of Pathology. PMID 28295365 DOI: 10.1002/Path.4894  0.367
2017 Chooback N, Ho C, Shen Y, Tsang ES, Zhao Y, Mungall AJ, Moore R, Lim HJ, Renouf DJ, Gelmon KA, Yip S, Jones S, Laskin JJ, Marra M. Whole genome and transcriptome sequencing of lung cancer: Options for personalized cancer treatment. Journal of Clinical Oncology. 35. DOI: 10.1200/Jco.2017.35.15_Suppl.E20567  0.36
2017 Lim HJ, Schrader KA, Young S, Nelson J, Fok A, Pleasance E, Jones M, Shen Y, Armstrong L, Virani A, Rassekh SR, Deyell R, Yip S, Roscoe R, Karsan A, ... Marra M, et al. Management of germline findings revealed throughout the course of tumor-normal whole genome sequencing in oncology. Journal of Clinical Oncology. 35: e13113-e13113. DOI: 10.1200/Jco.2017.35.15_Suppl.E13113  0.403
2017 Grande BM, Gerhard DS, Griner NB, Casper C, Namirembe C, Omoding A, Orem J, Mbulaiteye SM, Mullighan CG, Sandlund JT, Alexander T, Choi JK, Abramson JS, Gross TG, Noy A, ... ... Marra MA, et al. Burkitt Lymphoma Genome Sequencing Project (BLGSP): Integrative Genomic and Transcriptomic Characterization of Burkitt Lymphoma Blood. 130: 39-39. DOI: 10.1182/Blood.V130.Suppl_1.39.39  0.846
2017 Arthur SE, Mottok A, Alcaide M, Rushton C, Grande BM, Ennishi D, Davidson J, Bushell KR, Gascoyne RD, Marra MA, Connors JM, Morin GB, Scott DW, Steidl C, Morin RD. Functional Investigation of the Gene NFKBIZ and the Impact of 3'UTR Mutations in Diffuse Large B-Cell Lymphoma Blood. 130: 1228-1228. DOI: 10.1182/Blood.V130.Suppl_1.1228.1228  0.823
2017 Zhao EY, Shen Y, Pleasance E, Kasaian K, Jones MR, Ch'ng C, Reisle C, Eirew P, Mungall K, Thiessen N, Ma Y, Fok A, Mungall AJ, Zhao Y, Moore R, ... ... Marra MA, et al. Abstract 2473: Breast cancer whole genomes link homologous recombination deficiency (HRD) with therapeutic outcomes Cancer Research. 77: 2473-2473. DOI: 10.1158/1538-7445.Am2017-2473  0.314
2017 Ennishi D, Bashashati A, Saberi S, Mottok A, Meissner B, Boyle M, Ben-Neriah S, Kridel R, Savage KJ, Sehn LH, Connors JM, Morin RD, Marra MA, Shah SP, Steidl C, et al. Abstract 2445: Integrative genetic analysis identifies therapeutic relevance of cell of origin-specific genetic alterations in diffuse large B-cell lymphoma Cancer Research. 77: 2445-2445. DOI: 10.1158/1538-7445.Am2017-2445  0.647
2017 Wong D, Lounsbury K, LeBlanc V, Chittaranjan S, Marra M, Yip S. Csig-12. Exploring The Functional Relationship Between Capicua (Cic) And Ataxin-1-Like (Atxn1L) In Glioma Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.207  0.444
2016 Sheffield BS, Tessier-Cloutier B, Li-Chang H, Shen Y, Pleasance E, Kasaian K, Li Y, Jones SJ, Lim HJ, Renouf DJ, Huntsman DG, Yip S, Laskin J, Marra M, Schaeffer DF. Personalized oncogenomics in the management of gastrointestinal carcinomas-early experiences from a pilot study. Current Oncology (Toronto, Ont.). 23: e571-e575. PMID 28050146 DOI: 10.3747/Co.23.3165  0.361
2016 Kridel R, Chan FC, Mottok A, Boyle M, Farinha P, Tan K, Meissner B, Bashashati A, McPherson A, Roth A, Shumansky K, Yap D, Ben-Neriah S, Rosner J, Smith MA, ... ... Marra MA, et al. Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study. Plos Medicine. 13: e1002197. PMID 27959929 DOI: 10.1371/Journal.Pmed.1002197  0.598
2016 Topham JT, Marra MA. Sequencing Strategies to Guide Decision Making in Cancer Treatment. Plos Medicine. 13: e1002189. PMID 27923042 DOI: 10.1371/Journal.Pmed.1002189  0.318
2016 Pellacani D, Bilenky M, Kannan N, Heravi-Moussavi A, Knapp DJ, Gakkhar S, Moksa M, Carles A, Moore R, Mungall AJ, Marra MA, Jones SJ, Aparicio S, Hirst M, Eaves CJ. Analysis of Normal Human Mammary Epigenomes Reveals Cell-Specific Active Enhancer States and Associated Transcription Factor Networks. Cell Reports. 17: 2060-2074. PMID 27851968 DOI: 10.1016/J.Celrep.2016.10.058  0.368
2016 Costa S, Regier DA, Meissner B, Cromwell I, Ben-Neriah S, Chavez E, Hung S, Steidl C, Scott DW, Marra MA, Peacock SJ, Connors JM. A time-and-motion approach to micro-costing of high-throughput genomic assays. Current Oncology (Toronto, Ont.). 23: 304-313. PMID 27803594 DOI: 10.3747/Co.23.2987  0.339
2016 Zahir FR, Tucker T, Mayo S, Brown CJ, Lim EL, Taylor J, Marra MA, Hamdan FF, Michaud JL, Friedman JM. Intragenic CNVs for epigenetic regulatory genes in intellectual disability: Survey identifies pathogenic and benign single exon changes. American Journal of Medical Genetics. Part A. 170: 2916-2926. PMID 27748065 DOI: 10.1002/Ajmg.A.37669  0.387
2016 Ooms AH, Gadd S, Gerhard DS, Smith MA, Guidry Auvil JM, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Ma Y, Zong Z, Mungall AJ, Moore RA, ... Marra MA, et al. Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27702824 DOI: 10.1158/1078-0432.Ccr-16-0985  0.355
2016 Grinshtein N, Rioseco CC, Marcellus R, Uehling D, Aman A, Lun X, Muto O, Podmore L, Lever J, Shen Y, Blough MD, Cairncross GJ, Robbins SM, Jones SJ, Marra MA, et al. Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells. Oncotarget. PMID 27449082 DOI: 10.18632/Oncotarget.10661  0.331
2016 Zipeto MA, Court AC, Sadarangani A, Delos Santos NP, Balaian L, Chun HJ, Pineda G, Morris SR, Mason CN, Geron I, Barrett C, Goff DJ, Wall R, Pellecchia M, Minden M, ... ... Marra MA, et al. ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis. Cell Stem Cell. PMID 27292188 DOI: 10.1016/J.Stem.2016.05.004  0.333
2016 LeBlanc VG, Marra MA. DNA methylation in adult diffuse gliomas. Briefings in Functional Genomics. PMID 27288434 DOI: 10.1093/Bfgp/Elw019  0.33
2016 Chong LC, Twa DD, Mottok A, Ben-Neriah S, Woolcock BW, Zhao Y, Savage KJ, Marra MA, Scott DW, Gascoyne RD, Morin RD, Mungall AJ, Steidl C. Comprehensive characterization of programmed death ligand structural rearrangements in B-cell non-Hodgkin lymphomas. Blood. PMID 27268263 DOI: 10.1182/Blood-2015-11-683003  0.604
2016 Alassiri AH, Ali RH, Shen Y, Lum A, Strahlendorf C, Deyell R, Rassekh R, Sorensen PH, Laskin J, Marra M, Yip S, Lee CH, Ng TL. ETV6-NTRK3 Is Expressed in a Subset of ALK-Negative Inflammatory Myofibroblastic Tumors. The American Journal of Surgical Pathology. PMID 27259007 DOI: 10.1097/Pas.0000000000000677  0.406
2016 McPherson A, Roth A, Laks E, Masud T, Bashashati A, Zhang AW, Ha G, Biele J, Yap D, Wan A, Prentice LM, Khattra J, Smith MA, Nielsen CB, Mullaly SC, ... ... Marra MA, et al. Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer. Nature Genetics. PMID 27182968 DOI: 10.1038/Ng.3573  0.416
2016 Parker JD, Shen Y, Pleasance E, Li Y, Schein JE, Zhao Y, Moore R, Wegrzyn-Woltosz J, Savage KJ, Weng AP, Gascoyne RD, Jones S, Marra M, Laskin J, Karsan A. Molecular etiology of an indolent lymphoproliferative disorder determined by whole-genome sequencing. Cold Spring Harbor Molecular Case Studies. 2: a000679. PMID 27148583 DOI: 10.1101/mcs.a000679  0.382
2016 Maxson JE, Ries RE, Wang YC, Gerbing RB, Kolb EA, Thompson SL, Guidry Auvil JM, Marra MA, Ma Y, Zong Z, Mungall AJ, Moore R, Long W, Gesuwan P, Davidsen TM, et al. CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML. Blood. PMID 27143256 DOI: 10.1182/Blood-2016-04-709899  0.395
2016 Craig DW, Nasser S, Corbett R, Chan SK, Murray L, Legendre C, Tembe W, Adkins J, Kim N, Wong S, Baker A, Enriquez D, Pond S, Pleasance E, Mungall AJ, ... ... Marra MA, et al. A somatic reference standard for cancer genome sequencing. Scientific Reports. 6: 24607. PMID 27094764 DOI: 10.1038/Srep24607  0.492
2016 Oh S, Flynn RA, Floor SN, Purzner J, Martin L, Do BT, Schubert S, Vaka D, Morrissy S, Li Y, Kool M, Hovestadt V, Jones DT, Northcott PA, Risch T, ... ... Marra MA, et al. Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress. Oncotarget. 7: 28169-82. PMID 27058758 DOI: 10.18632/Oncotarget.8612  0.34
2016 Pineda G, Lennon KM, Delos Santos NP, Lambert-Fliszar F, Riso GL, Lazzari E, Marra MA, Morris S, Sakaue-Sawano A, Miyawaki A, Jamieson CH. Tracking of Normal and Malignant Progenitor Cell Cycle Transit in a Defined Niche. Scientific Reports. 6: 23885. PMID 27041210 DOI: 10.1038/Srep23885  0.332
2016 Chun HE, Lim EL, Heravi-Moussavi A, Saberi S, Mungall KL, Bilenky M, Carles A, Tse K, Shlafman I, Zhu K, Qian JQ, Palmquist DL, He A, Long W, Goya R, ... ... Marra MA, et al. Genome-Wide Profiles of Extra-cranial Malignant Rhabdoid Tumors Reveal Heterogeneity and Dysregulated Developmental Pathways. Cancer Cell. 29: 394-406. PMID 26977886 DOI: 10.1016/J.Ccell.2016.02.009  0.8
2016 Morrissy AS, Garzia L, Shih DJ, Zuyderduyn S, Huang X, Skowron P, Remke M, Cavalli FM, Ramaswamy V, Lindsay PE, Jelveh S, Donovan LK, Wang X, Luu B, Zayne K, ... ... Marra MA, et al. Divergent clonal selection dominates medulloblastoma at recurrence. Nature. PMID 26760213 DOI: 10.1038/Nature16478  0.559
2016 Pon JR, Marra MA. MEF2 transcription factors: developmental regulators and emerging cancer genes. Oncotarget. 7: 2297-312. PMID 26506234 DOI: 10.18632/Oncotarget.6223  0.36
2016 Pon JR, Marra MA. Clinical impact of molecular features in diffuse large B-cell lymphoma and follicular lymphoma. Blood. 127: 181-6. PMID 26447189 DOI: 10.1182/Blood-2015-07-658401  0.343
2016 Wong H, Jones M, Eirew P, Karasinska J, Schrader KA, Lim HJ, Shen Y, Jones S, Yip S, Laskin JJ, Marra M, Schaeffer DF, Renouf DJ. Comprehensive genomic analysis in metastatic pancreatic ductal adenocarcinoma (PDAC). Journal of Clinical Oncology. 34: 285-285. DOI: 10.1200/Jco.2016.34.4_Suppl.285  0.476
2016 Ries RE, Bolouri H, Farrar JE, Lim EL, Triche TJ, Tarlock K, Auvil JG, Hirsch BA, Raimondi SC, Ma Y, Marra MA, Aplenc R, Guest EM, Kolb EA, Gamis AS, et al. Alteration of Chromatin Modifiers and Misregulation of Transcription Factors Define the Genomic Profile of Infant AML Blood. 128: 774-774. DOI: 10.1182/Blood.V128.22.774.774  0.459
2016 Ennishi D, Bashashati A, Saberi S, Mottok A, Meissner B, Boyle M, Ben-Neriah S, Kridel R, Dominguez-Sola D, Savage KJ, Sehn LH, Connors JM, Morin RD, Marra MA, Shah SP, et al. Frequent Genetic Alterations of PI3K-AKT Pathway and Their Clinical Significance in Germinal Center B-Cell-like Diffuse Large B-Cell Lymphoma Blood. 128: 607-607. DOI: 10.1182/Blood.V128.22.607.607  0.632
2016 Farrar JE, Bolouri H, Ries RE, Triche TJ, Lim EL, Alonzo TA, Ma Y, Moore R, Mungall AJ, Marra MA, Auvil JG, Davidsen TM, Gesuwan P, Hermida LC, Kolb EA, et al. Marked Differences in the Genomic Landscape of Pediatric Compared to Adult Acute Myeloid Leukemia: A Report from the Children's Oncology Group and NCI/COG Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative Blood. 128: 595-595. DOI: 10.1182/Blood.V128.22.595.595  0.451
2016 Alexander TB, Gu Z, Choi JK, Loh ML, Horan J, Buldini B, Basso G, Elitzur S, Zwaan CM, Haas Vd, Yeoh AEJ, Reinhardt D, Tomizawa D, Lammens T, Moerloose BD, ... ... Marra MA, et al. Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia Blood. 128: 454-454. DOI: 10.1182/Blood.V128.22.454.454  0.39
2016 Mottok A, Chong L, Ben-Neriah S, Woolcock B, Zhao Y, Marra MA, Scott DW, Gascoyne RD, Mungall AJ, Steidl C. Characterization of Genomic Rearrangements Involving CIITA and SOCS1 Using Targeted Capture Sequencing of Archival Tissue Specimens Blood. 128: 2925-2925. DOI: 10.1182/Blood.V128.22.2925.2925  0.482
2016 Kridel R, Chan FC, Mottok A, Boyle M, Farinha P, Tan K, Meissner B, Bashashati A, Ben-Neriah S, Gine E, Ennishi D, Mungall AJ, Morin RD, Johnson NA, Sehn LH, ... ... Marra MA, et al. Targeted Sequencing Reveals Novel Gene Mutations Associated with Transformation and Early Progression in Follicular Lymphoma Blood. 128: 2919-2919. DOI: 10.1182/Blood.V128.22.2919.2919  0.639
2016 Tarlock K, Kaeding AJ, Alonzo TA, Loken MR, Ries RE, Pardo L, Gerbing R, Farrar JE, Guidry Auvil JM, Gerhard DS, Smith MA, Davidsen TM, Gesuwan P, Hermida LC, Marra MA, et al. Discovery and Validation of Cell-Surface Protein Mesothelin (MSLN) As a Novel Therapeutic Target in AML: Results from the COG/NCI Target AML Initiative Blood. 128: 2873-2873. DOI: 10.1182/Blood.V128.22.2873.2873  0.377
2016 Gerhard DS, Grande B, Griner N, Casper C, Gerdts SE, Omoding A, Orem J, Mbulaiteye SM, Ogwang MD, Reynolds SJ, Bhatia K, Ayers L, Choi JK, Mullighan CG, Sandlund JT, ... ... Marra MA, et al. Burkitt Lymphoma Genome Sequencing Project (BLGSP): Introduction Blood. 128: 1760-1760. DOI: 10.1182/Blood.V128.22.1760.1760  0.835
2016 Chan FC, Kridel R, Mottok A, Boyle M, Farinha P, Tan K, Meissner B, Bashashati A, McPherson A, Roth A, Shumansky K, Yap D, Ben-Neriah S, Rosner J, Smith MA, ... ... Marra MA, et al. Divergent Modes of Tumor Evolution Underlie Histological Transformation and Early Progression of Follicular Lymphoma Blood. 128: 1091-1091. DOI: 10.1182/Blood.V128.22.1091.1091  0.627
2016 Triche TJ, Farrar JE, Bolouri H, Ries RE, Lim EL, Alonzo TA, Ma Y, Moore R, Mungall AJ, Marra MA, Guidry Auvil JM, Davidsen TM, Gesuwan P, Hermida LC, Kolb EA, et al. Divergent Epigenomes in Pediatric and Adult Acute Myeloid Leukemia Implicate Cell of Origin and Transcriptional Silencing of Immune Responses As Sources of Clinically Relevant Heterogeneity: A Report from the Children's Oncology Group and NCI/COG Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative Blood. 128: 1046-1046. DOI: 10.1182/Blood.V128.22.1046.1046  0.43
2016 Bose P, Pleasance E, Jones M, Shen Y, Ch'ng C, Reisle C, Schein JE, Mungall A, Moore R, Ma Y, Sheffield BS, Thomson T, Rasmussen S, Lee C, Yip S, ... Marra MA, et al. Abstract PR02: Integrated genomic analysis of a recurrent ghost cell odontogenic carcinoma Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Pmsclingen15-Pr02  0.465
2016 Wong H, Karasinska JM, Jones M, Eirew P, Schrader K, Lim H, Shen Y, Jones S, Yip S, Laskin J, Marra M, Schaeffer DF, Renouf DJ. Abstract B81: Gene expression analysis demonstrates prognostic subtypes in metastatic pancreatic ductal adenocarcinoma (PDAC) Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-B81  0.445
2016 Gadd SL, Walz AL, Ooms AH, Huff V, Gerhard DS, Smith MA, Auvil JMG, Hermida L, Davidsen T, Gesuwan P, Meerzaman D, Ma Y, Marra MA, Dome JS, Mullighan CG, et al. Abstract LB-180: The genetic landscape of Wilms tumor Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-180  0.471
2016 Schrader KA, Chu’ng C, Zhao E, Wong H, Shen Y, Jones M, Thomson T, Lim H, Young S, Cremin C, Holt R, Eirew P, Karasinska J, Schein J, Zhao Y, ... ... Marra M, et al. Abstract 5226: Genomic analysis of pancreatic ductal adenocarcinoma in a patient with MUTYH-associated polyposis Cancer Research. 76: 5226-5226. DOI: 10.1158/1538-7445.Am2016-5226  0.456
2016 Laskin JJ, Shen Y, Renouf D, Jones M, Lim H, Fok A, Ho C, Deol B, Gelmon KA, Chia S, Moore R, Mungall A, Yip S, Jones S, Marra M. Abstract 2631: Restrictions on access to systemic therapy limit the application of whole genome sequencing in clinical care Cancer Research. 76: 2631-2631. DOI: 10.1158/1538-7445.Am2016-2631  0.414
2016 Laskin J, Ho C, Shen Y, Jones M, Gelmon KA, Lim H, Renouf DJ, Yip S, Tinker A, Khoo K, Lohrisch C, Chia S, Deol B, Schrader K, Ma Y, ... ... Marra M, et al. Availability of tumour gene expression data facilitates clinical decision-making for patients with advanced cancers Annals of Oncology. 27. DOI: 10.1093/Annonc/Mdw392.01  0.312
2016 Laskin J, Ha D, Chan T, Fok A, Gelmon K, Charters A, Yoshizawa R, Struve S, Ho C, Renouf D, Lim H, Simmons C, Taylor S, Tinker A, McGhie J, ... ... Marra M, et al. Clinicians identify high need to increase their genomic literacy to applied cancer genomics Annals of Oncology. 27: vi477. DOI: 10.1093/Annonc/Mdw387.16  0.368
2016 LeBlanc VG, Chittaranjan S, Firme M, Chan SY, Song J, Lee A, Yip S, Marra MA. PS2 - 167 CIC Deficiency is Associated with Dysregulation of Genes Involved in Cell Adhesion and Developmental Processes Canadian Journal of Neurological Sciences. 43. DOI: 10.1017/Cjn.2016.365  0.309
2016 Robertson G, Gunaratne P, Lerner S, Mungall A, Brooks D, Bowlby R, Sipahimalani P, Jones S, Marra M, Hoadley K, Kwiatkowski D, Rosenberg J, Weinstein J. 787 The Cancer Genome Atlas (TCGA) project analysis of micro-RNA and gene expression subtypes of high-grade, muscle-invasive urothelial carcinoma European Urology Supplements. 15: e787. DOI: 10.1016/S1569-9056(16)60789-3  0.344
2015 Laskin J, Jones S, Aparicio S, Chia S, Ch'ng C, Deyell R, Eirew P, Fok A, Gelmon K, Ho C, Huntsman D, Jones M, Kasaian K, Karsan A, Leelakumari S, ... ... Marra MA, et al. Lessons learned from the application of whole-genome analysis to the treatment of patients with advanced cancers. Cold Spring Harbor Molecular Case Studies. 1: a000570. PMID 27148575 DOI: 10.1101/mcs.a000570  0.313
2015 Kasaian K, Wiseman SM, Walker BA, Schein JE, Zhao Y, Hirst M, Moore RA, Mungall AJ, Marra MA, Jones SJ. The genomic and transcriptomic landscape of anaplastic thyroid cancer: implications for therapy. Bmc Cancer. 15: 984. PMID 26680454 DOI: 10.1186/S12885-015-1955-9  0.318
2015 Perlman EJ, Gadd S, Arold ST, Radhakrishnan A, Gerhard DS, Jennings L, Huff V, Guidry Auvil JM, Davidsen TM, Dome JS, Meerzaman D, Hsu CH, Nguyen C, Anderson J, Ma Y, ... ... Marra MA, et al. MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours. Nature Communications. 6: 10013. PMID 26635203 DOI: 10.1038/Ncomms10013  0.4
2015 Nielsen JS, Sedgwick C, Shahid A, Zong Z, Brumme ZL, Yu S, Liu L, Kroeger DR, Treon SP, Connors JM, Gascoyne RD, Berry BR, Marra MA, Morin RD, Macpherson N, et al. Toward personalized lymphoma immunotherapy: Identification of common driver mutations recognized by patient CD8+ T cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26631611 DOI: 10.1158/1078-0432.Ccr-15-2023  0.786
2015 Holm F, Hellqvist E, Mason CN, Ali SA, Delos-Santos N, Barrett CL, Chun HJ, Minden MD, Moore RA, Marra MA, Runza V, Frazer KA, Sadarangani A, Jamieson CH. Reversion to an embryonic alternative splicing program enhances leukemia stem cell self-renewal. Proceedings of the National Academy of Sciences of the United States of America. PMID 26621726 DOI: 10.1182/Blood.V126.23.1227.1227  0.343
2015 Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C, Wheeler DA, Murray BA, Schmidt L, Vocke CD, Peto M, Al Mamun AA, Shinbrot E, Sethi A, Brooks S, ... ... Marra MA, et al. Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. The New England Journal of Medicine. PMID 26536169 DOI: 10.1056/Nejmoa1505917  0.45
2015 LeBlanc VG, Marra MA. Next-Generation Sequencing Approaches in Cancer: Where Have They Brought Us and Where Will They Take Us? Cancers. 7: 1925-58. PMID 26404381 DOI: 10.3390/Cancers7030869  0.345
2015 Kridel R, Mottok A, Farinha P, Ben-Neriah S, Ennishi D, Zheng Y, Chavez EA, Shulha HP, Tan K, Chan FC, Boyle M, Meissner B, Telenius A, Sehn LH, Marra MA, et al. Cell-of-origin of transformed follicular lymphoma. Blood. PMID 26307535 DOI: 10.1182/Blood-2015-06-649905  0.339
2015 Chu A, Robertson G, Brooks D, Mungall AJ, Birol I, Coope R, Ma Y, Jones S, Marra MA. Large-scale profiling of microRNAs for The Cancer Genome Atlas. Nucleic Acids Research. PMID 26271990 DOI: 10.1093/Nar/Gkv808  0.373
2015 Pon JR, Wong J, Saberi S, Alder O, Moksa M, Grace Cheng SW, Morin GB, Hoodless PA, Hirst M, Marra MA. MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation. Nature Communications. 6: 7953. PMID 26245647 DOI: 10.1038/Ncomms8953  0.431
2015 Lebovitz CB, Robertson AG, Goya R, Jones SJ, Morin RD, Marra MA, Gorski SM. Cross-cancer profiling of molecular alterations within the human autophagy interaction network. Autophagy. 0. PMID 26208877 DOI: 10.1080/15548627.2015.1067362  0.814
2015 Schmouth JF, Arenillas D, Corso-Díaz X, Xie YY, Bohacec S, Banks KG, Bonaguro RJ, Wong SH, Jones SJ, Marra MA, Simpson EM, Wasserman WW. Combined serial analysis of gene expression and transcription factor binding site prediction identifies novel-candidate-target genes of Nr2e1 in neocortex development. Bmc Genomics. 16: 545. PMID 26204903 DOI: 10.1186/S12864-015-1770-3  0.328
2015 Bose P, Pleasance ED, Jones M, Shen Y, Ch'ng C, Reisle C, Schein JE, Mungall AJ, Moore R, Ma Y, Sheffield BS, Thomson T, Rasmussen S, Ng T, Yip S, ... ... Marra MA, et al. Integrative genomic analysis of ghost cell odontogenic carcinoma. Oral Oncology. 51: e71-5. PMID 26173781 DOI: 10.1016/J.Oraloncology.2015.06.013  0.337
2015 Cusulin C, Chesnelong C, Bose P, Bilenky M, Kopciuk K, Chan JA, Cairncross JG, Jones SJ, Marra MA, Luchman HA, Weiss S. Precursor States of Brain Tumor Initiating Cell Lines Are Predictive of Survival in Xenografts and Associated with Glioblastoma Subtypes. Stem Cell Reports. PMID 26095605 DOI: 10.1016/J.Stemcr.2015.05.010  0.314
2015 Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, ... ... Marra MA, et al. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. The New England Journal of Medicine. 372: 2481-98. PMID 26061751 DOI: 10.1056/Nejmoa1402121  0.734
2015 Sadarangani A, Pineda G, Lennon KM, Chun HJ, Shih A, Schairer AE, Court AC, Goff DJ, Prashad SL, Geron I, Wall R, McPherson JD, Moore RA, Pu M, Bao L, ... ... Marra MA, et al. GLI2 inhibition abrogates human leukemia stem cell dormancy. Journal of Translational Medicine. 13: 98. PMID 25889765 DOI: 10.1186/S12967-015-0453-9  0.303
2015 Zahir FR, Marra MA. Use of affymetrix arrays in the diagnosis of gene copy-number variation. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. 85: 8.13.1-8.13.13. PMID 25827348 DOI: 10.1002/0471142905.Hg0813S85  0.367
2015 Sheffield BS, Tinker AV, Shen Y, Hwang H, Li-Chang HH, Pleasance E, Ch'ng C, Lum A, Lorette J, McConnell YJ, Sun S, Jones SJ, Gown AM, Huntsman DG, Schaeffer DF, ... ... Marra MA, et al. Personalized oncogenomics: clinical experience with malignant peritoneal mesothelioma using whole genome sequencing. Plos One. 10: e0119689. PMID 25798586 DOI: 10.1371/Journal.Pone.0119689  0.446
2015 Lim EL, Trinh DL, Scott DW, Chu A, Krzywinski M, Zhao Y, Robertson AG, Mungall AJ, Schein J, Boyle M, Mottok A, Ennishi D, Johnson NA, Steidl C, Connors JM, ... ... Marra MA, et al. Comprehensive miRNA sequence analysis reveals survival differences in diffuse large B-cell lymphoma patients. Genome Biology. 16: 18. PMID 25723320 DOI: 10.1186/S13059-014-0568-Y  0.583
2015 Twa DD, Mottok A, Chan FC, Ben-Neriah S, Woolcock BW, Tan KL, Mungall AJ, McDonald H, Zhao Y, Lim RS, Nelson BH, Milne K, Shah SP, Morin RD, Marra MA, et al. Recurrent genomic rearrangements in primary testicular lymphoma. The Journal of Pathology. 236: 136-41. PMID 25712539 DOI: 10.1002/Path.4522  0.623
2015 Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, ... ... Marra MA, et al. Integrative analysis of 111 reference human epigenomes. Nature. 518: 317-30. PMID 25693563 DOI: 10.1038/Nature14248  0.357
2015 Anglesio MS, Bashashati A, Wang YK, Senz J, Ha G, Yang W, Aniba MR, Prentice LM, Farahani H, Li Chang H, Karnezis AN, Marra MA, Yong PJ, Hirst M, Gilks B, et al. Multifocal endometriotic lesions associated with cancer are clonal and carry a high mutation burden. The Journal of Pathology. 236: 201-9. PMID 25692284 DOI: 10.1002/Path.4516  0.401
2015 Elliott G, Hong C, Xing X, Zhou X, Li D, Coarfa C, Bell RJ, Maire CL, Ligon KL, Sigaroudinia M, Gascard P, Tlsty TD, Harris RA, Schalkwyk LC, Bilenky M, ... ... Marra MA, et al. Intermediate DNA methylation is a conserved signature of genome regulation. Nature Communications. 6: 6363. PMID 25691127 DOI: 10.1038/Ncomms7363  0.317
2015 Gascard P, Bilenky M, Sigaroudinia M, Zhao J, Li L, Carles A, Delaney A, Tam A, Kamoh B, Cho S, Griffith M, Chu A, Robertson G, Cheung D, Li I, ... ... Marra MA, et al. Epigenetic and transcriptional determinants of the human breast. Nature Communications. 6: 6351. PMID 25690954 DOI: 10.1038/Ncomms7351  0.562
2015 Walz AL, Ooms A, Gadd S, Gerhard DS, Smith MA, Guidry Auvil JM, Guidry Auvil JM, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Bowlby R, Brooks D, ... ... Marra MA, et al. Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors. Cancer Cell. 27: 286-97. PMID 25670082 DOI: 10.1016/J.Ccell.2015.01.003  0.388
2015 Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, ... ... Marra M, et al. The Release 6 reference sequence of the Drosophila melanogaster genome. Genome Research. 25: 445-58. PMID 25589440 DOI: 10.1101/Gr.185579.114  0.399
2015 Kulic I, Robertson G, Chang L, Baker JH, Lockwood WW, Mok W, Fuller M, Fournier M, Wong N, Chou V, Robinson MD, Chun HJ, Gilks B, Kempkes B, Thomson TA, ... ... Marra M, et al. Loss of the Notch effector RBPJ promotes tumorigenesis. The Journal of Experimental Medicine. 212: 37-52. PMID 25512468 DOI: 10.1084/Jem.20121192  0.372
2015 Eirew P, Steif A, Khattra J, Ha G, Yap D, Farahani H, Gelmon K, Chia S, Mar C, Wan A, Laks E, Biele J, Shumansky K, Rosner J, McPherson A, ... ... Marra MA, et al. Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution. Nature. 518: 422-6. PMID 25470049 DOI: 10.1038/Nature13952  0.385
2015 Chan FC, Telenius A, Healy S, Ben-Neriah S, Mottok A, Lim R, Drake M, Hu S, Ding J, Ha G, Scott DW, Kridel R, Bashashati A, Rogic S, Johnson N, ... ... Marra MA, et al. An RCOR1 loss-associated gene expression signature identifies a prognostically significant DLBCL subgroup. Blood. 125: 959-66. PMID 25395426 DOI: 10.1182/Blood-2013-06-507152  0.637
2015 Pon JR, Marra MA. Driver and passenger mutations in cancer. Annual Review of Pathology. 10: 25-50. PMID 25340638 DOI: 10.1146/Annurev-Pathol-012414-040312  0.435
2015 Koyama T, Jones S, Utro F, Ma Y, Rhrissorrakrai K, Shen Y, Carmeli B, Jones M, Waks Z, Pleasance E, Norel R, Moore R, Bilal E, Mungall AJ, Beaty K, ... ... Marra M, et al. Implementation of Watson Genomic Analytics processing to improve the efficiency of interpreting whole genome sequencing data on patients with advanced cancers. Journal of Clinical Oncology. 33: e12549-e12549. DOI: 10.1200/Jco.2015.33.15_Suppl.E12549  0.43
2015 Remke M, Cavalli F, Morrissy A, Ramaswamy V, Jones D, Packer R, Bouffet E, Bader G, Borkhardt A, Pfister S, Jabado N, Marra M, Taylor MD. Integrated genomics elucidates relative spatial homogeneity of embryonal brain tumors Molecular and Cellular Pediatrics. 2: A10. DOI: 10.1186/2194-7791-2-S1-A10  0.356
2015 Tarlock K, Hansen ME, Hylkema T, Ries R, Farrar JE, Auvil JG, Gerhard DS, Smith MA, Davidsen TM, Gesuwan P, Hermida LC, Marra MA, Mungall AJ, Mungall K, Ma Y, et al. Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative Blood. 126: 87-87. DOI: 10.1182/Blood.V126.23.87.87  0.407
2015 Lim EL, Trinh DL, Ries RE, Ma Y, Topham J, Hughes MD, Pleasance E, Mungall AJ, Moore R, Zhao Y, Gerhard DS, Oehler V, Kolb EA, Gamis AS, Smith MA, ... ... Marra MA, et al. Comprehensive Sequence Analysis of Relapse and Refractory Pediatric Acute Myeloid Leukemia Identifies miRNA and mRNA Transcripts Associated with Treatment Resistance - a Report from the COG/NCI-Target AML Initiative Blood. 126: 687-687. DOI: 10.1182/Blood.V126.23.687.687  0.324
2015 Farrar JE, Alonzo TA, Ries RE, Gerbing RB, Guidry Auvil JM, Davidsen TM, Gesuwan P, Hermida LC, Marra MA, Mungall AJ, Mungall K, Ma Y, Long W, Zong S, Kolb EA, et al. ASXL1 and ASXL2 Mutations in Childhood AML Are Strongly Associated with t(8;21) but Do Not Independently Impact on Prognosis: A Report from the Children's Oncology Group and NCI/COG Target Initiative Blood. 126: 2587-2587. DOI: 10.1182/Blood.V126.23.2587.2587  0.422
2015 Pineda G, Lennon KM, Delos-Santos NP, Lambert-Fliszar F, Riso GL, Marra MA, Morris S, Sakaue-Sawano A, Miyawaki A, Jamieson CH. Tracking Normal and Chronic Myeloid Leukemia Progenitor Cell Cycle Kinetics in a Defined Niche Using Live Time Lapse Confocal Imaging with Fucci2BL a Novel Lentiviral Bicistronic Reporter Blood. 126: 1863-1863. DOI: 10.1182/Blood.V126.23.1863.1863  0.343
2015 Maxson JE, Ries R, Wang Y, Gerbing RB, Kolb EA, Thompson SL, Guidry Auvil JM, Marra MA, Ma Y, Zong S, Mungall AJ, Moore R, Long W, Gesuwan P, Davidsen TM, et al. CSF3R Mutations Represent a Novel Therapeutic Target in Pediatric AML with a High Degree of Overlap with CEBPA Mutations: a Report from COG AAML0531 and COG/NCI Target AML Initiative Blood. 126: 174-174. DOI: 10.1182/Blood.V126.23.174.174  0.435
2015 Chin D, Kutny MA, Grim J, Gerbing RB, Miller K, Farrar JE, Guidry Auvil JM, Smith MA, Gerhard DS, Davidsen TM, Gesuwan P, Hermida LC, Marra MA, Mungall AJ, Moore R, et al. Comprehensive Genomic and Transcript Profiling of CBL Gene in Childhood AML: A Report from Children's Oncology Group Studies AAML03P1, AAML0531 and COG/NCI Target AML Initiative Blood. 126: 170-170. DOI: 10.1182/Blood.V126.23.170.170  0.461
2015 Ostronoff F, Ries RE, Gerbing RB, Marra MA, Yussanne M, Long W, Zong S, Mungall K, Andrew A, Gerhard DS, Smith MA, Patee G, Davidsen TM, Hermida LC, Farrar JE, et al. Rearrangements in Nucleoporin Family of Genes in Childhood Acute Myeloid Leukemia: A Report from Children Oncology Group and NCI/COG Target AML Initiative Blood. 126: 169-169. DOI: 10.1182/Blood.V126.23.169.169  0.347
2015 Kutny MA, Alonzo TA, Wang Y, Ries R, Farrar JE, Guidry Auvil JM, Smith MA, Gerhard DS, Davidsen TM, Gesuwan P, Hermida LC, Marra MA, Mungall AJ, Moore R, Long W, et al. TET2 Mutations Are Highly Associated with RUNX1-RUNX1T1 Translocations and NPMc+ in Childhood AML: a Report from Children's Oncology Group AAML03P1, AAML0531 and NCI/COG Target AML Initiative Blood. 126: 1368-1368. DOI: 10.1182/Blood.V126.23.1368.1368  0.421
2015 Ennishi D, Mottok A, Shulha H, Farinha P, Chan FC, Meissner B, Boyle M, Ben-Neriah S, Hother CE, Kridel R, Morin R, Marra MA, Savage KJ, Sehn LH, Connors JM, et al. Genetic Alterations of Gα13 Signaling Pathway with BCL2 over-Expression Confers Lymphoma Dissemination and Inferior Outcome in Germinal Center B Cell Diffuse Large B Cell Lymphoma Blood. 126: 111-111. DOI: 10.1182/Blood.V126.23.111.111  0.644
2015 Ennishi D, Mottok A, Savage KJ, Ben-Neriah S, Shulha H, Farinha P, Chan FC, Meissner B, Boyle M, Hother CE, Kridel R, Morin R, Marra MA, Sehn LH, Steidl C, et al. Comprehensive MYC and BCL2 Genetic Profiling in De Novo Diffuse Large B-Cell Lymphoma Demonstrates Clinically Relevant Genetic Alterations According to Cell of Origin Subtype Blood. 126: 109-109. DOI: 10.1182/Blood.V126.23.109.109  0.631
2015 Ramos P, Karnezis AN, Craig DW, Sekulic A, Russell ML, Hendricks WPD, Corneveaux JJ, Barrett MT, Shumansky K, Yang Y, Shah SP, Prentice LM, Marra MA, Kiefer J, Zismann VL, et al. Abstract POSTER-BIOL-1327: Small cell carcinoma of the ovary, hypercalcemic type displays frequent inactivating germline and somatic mutations in SMARCA4 Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-Poster-Biol-1327  0.449
2015 Anglesio MS, Bashashati A, Wang Y, Ha G, Senz J, Yang W, Kalloger SE, Prentice LM, Yanagida S, Salamanca C, Soukhatcheva G, Kazernis A, Chang H, Mes-Mason A, Okamoto A, ... Marra MA, et al. Abstract AS18: The somatic mutational landscape of endometriosis associated ovarian cancers and precursor lesions Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-As18  0.446
2015 Sun S, Gelmon KA, Chia S, Lohrisch C, Shenkier T, Villa D, Shen Y, Jones M, Pleasance E, Kasaian K, Eirew P, Leelakumari S, Ma Y, Ng T, Yip S, ... ... Marra MA, et al. Abstract 1122: Personalized oncogenomics in advanced stage breast cancer Cancer Research. 75: 1122-1122. DOI: 10.1158/1538-7445.Am2015-1122  0.416
2015 Garzia L, Kijima N, Morrissy A, Donovan L, Wu X, Luu B, Ramaswamy V, Peacock J, Lopez-Holgado B, Wang X, Cavalli F, Rolider A, Shih D, Skowron P, Lee J, ... ... Marra M, et al. PTPS-08HEMATOGENOUS DISSEMINATION OF MEDULLOBLASTOMA METASTASES TO THE LEPTOMENINGES Neuro-Oncology. 17: v180.4-v180. DOI: 10.1093/Neuonc/Nov228.08  0.34
2015 Grinshtein N, Rioseco C, Uehling D, Aman A, Luchman A, Senger D, Robbins S, Cairncross G, Datti A, Wrana J, Jones S, Marra M, Moran M, Al-awar R, Weiss S, et al. ATPS-28COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS Neuro-Oncology. 17: v24.2-v24. DOI: 10.1093/Neuonc/Nov204.28  0.321
2015 Remke M, Cavalli F, Morrissy AS, Ramaswamy V, Jones D, Packer R, Bouffet E, Bader G, Pfister S, Jabado N, Marra M, Taylor M. MB-21 * INTEGRATED GENOMICS ELUCIDATES RELATIVE SPATIAL HOMOGENEITY OF EMBRYONAL BRAIN TUMORS Neuro-Oncology. 17: iii24-iii24. DOI: 10.1093/Neuonc/Nov061.97  0.366
2015 Lim H, Schrader K, Young S, Fok A, Pleasance E, Jones M, Shen Y, Armstrong L, Virani A, Rassekh S, Deyell R, Yip S, Roscoe R, Karsan A, Marra M, et al. 232 Management of germline findings revealed throughout the course of tumor-normal whole genome sequencing in oncology European Journal of Cancer. 51: S37-S38. DOI: 10.1016/S0959-8049(16)30119-8  0.385
2015 Walz A, Ooms A, Gadd S, Gerhard D, Smith M, Guidry Auvil J, Meerzaman D, Chen Q, Hsu C, Yan C, Nguyen C, Hu Y, Bowlby R, Brooks D, Ma Y, ... ... Marra M, et al. Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors Cancer Cell. 27: 426. DOI: 10.1016/J.Ccell.2015.02.008  0.362
2014 Lim H, Virani A, Fok A, Karsan A, Renouf D, Gelmon KA, Yip S, Chia S, Sun S, Tinker A, Lee SJ, Rassekh R, Deyell R, Roscoe R, Jones S, ... ... Marra M, et al. 1615PPRACTICAL GUIDELINES FOR ETHICAL AND POLICY ISSUES THAT ARISE FROM THE CLINICAL APPLICATION OF WHOLE GENOME SEQUENCING IN CANCER PATIENTS. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 25: iv559. PMID 28172389 DOI: 10.1093/Annonc/Mdu358.46  0.346
2014 Laskin J, Moore R, Shen Y, Lim H, Gelmon KA, Renouf D, Yip S, Huntsman D, Ng T, Mungall A, Fok A, Ho C, Chia S, Leelakumari S, Kasaian K, ... ... Marra M, et al. 1570ODEMONSTRATION OF TEMPORAL HETEROGENEITY IDENTIFIED BY GENOME SEQUENCING AND THE POTENTIAL EFFECT ON TREATMENT DECISIONS FOR ADVANCED CANCER PATIENTS. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 25: iv546. PMID 28172072 DOI: 10.1093/Annonc/Mdu358.1  0.422
2014 Lowdon RF, Zhang B, Bilenky M, Mauro T, Li D, Gascard P, Sigaroudinia M, Farnham PJ, Bastian BC, Tlsty TD, Marra MA, Hirst M, Costello JF, Wang T, Cheng JB. Regulatory network decoded from epigenomes of surface ectoderm-derived cell types. Nature Communications. 5: 5442. PMID 25421844 DOI: 10.1038/Ncomms6442  0.317
2014 Chittaranjan S, Chan S, Yang C, Yang KC, Chen V, Moradian A, Firme M, Song J, Go NE, Blough MD, Chan JA, Cairncross JG, Gorski SM, Morin GB, Yip S, ... Marra MA, et al. Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity. Oncotarget. 5: 7960-79. PMID 25277207 DOI: 10.18632/Oncotarget.2401  0.366
2014 Alder O, Cullum R, Lee S, Kan AC, Wei W, Yi Y, Garside VC, Bilenky M, Griffith M, Morrissy AS, Robertson GA, Thiessen N, Zhao Y, Chen Q, Pan D, ... ... Marra MA, et al. Hippo signaling influences HNF4A and FOXA2 enhancer switching during hepatocyte differentiation. Cell Reports. 9: 261-71. PMID 25263553 DOI: 10.1016/J.Celrep.2014.08.046  0.551
2014 Ha G, Roth A, Khattra J, Ho J, Yap D, Prentice LM, Melnyk N, McPherson A, Bashashati A, Laks E, Biele J, Ding J, Le A, Rosner J, Shumansky K, ... Marra MA, et al. TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data. Genome Research. 24: 1881-93. PMID 25060187 DOI: 10.1101/Gr.180281.114  0.453
2014 Firme MR, Marra MA. The molecular landscape of pediatric brain tumors in the next-generation sequencing era. Current Neurology and Neuroscience Reports. 14: 474. PMID 25037717 DOI: 10.1007/S11910-014-0474-4  0.322
2014 Dias C, Rupps R, Millar B, Choi K, Marra M, Demos M, Kratz LE, Boerkoel CF. Desmosterolosis: an illustration of diagnostic ambiguity of cholesterol synthesis disorders. Orphanet Journal of Rare Diseases. 9: 94. PMID 24961299 DOI: 10.1186/1750-1172-9-94  0.318
2014 Vanner RJ, Remke M, Gallo M, Selvadurai HJ, Coutinho F, Lee L, Kushida M, Head R, Morrissy S, Zhu X, Aviv T, Voisin V, Clarke ID, Li Y, Mungall AJ, ... ... Marra MA, et al. Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma. Cancer Cell. 26: 33-47. PMID 24954133 DOI: 10.1016/J.Ccr.2014.05.005  0.35
2014 Jamshidi F, Pleasance E, Li Y, Shen Y, Kasaian K, Corbett R, Eirew P, Lum A, Pandoh P, Zhao Y, Schein JE, Moore RA, Rassekh R, Huntsman DG, Knowling M, ... ... Marra MA, et al. Diagnostic value of next-generation sequencing in an unusual sphenoid tumor. The Oncologist. 19: 623-30. PMID 24807916 DOI: 10.1634/Theoncologist.2013-0390  0.451
2014 Berg T, Thoene S, Yap D, Wee T, Schoeler N, Rosten P, Lim E, Bilenky M, Mungall AJ, Oellerich T, Lee S, Lai CK, Umlandt P, Salmi A, Chang H, ... ... Marra MA, et al. A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis. Blood. 123: 3914-24. PMID 24802772 DOI: 10.1182/Blood-2012-12-473439  0.635
2014 Janbon G, Ormerod KL, Paulet D, Byrnes EJ, Yadav V, Chatterjee G, Mullapudi N, Hon CC, Billmyre RB, Brunel F, Bahn YS, Chen W, Chen Y, Chow EW, Coppée JY, ... ... Marra M, et al. Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. Plos Genetics. 10: e1004261. PMID 24743168 DOI: 10.1371/Journal.Pgen.1004261  0.464
2014 Ramos P, Karnezis AN, Craig DW, Sekulic A, Russell ML, Hendricks WP, Corneveaux JJ, Barrett MT, Shumansky K, Yang Y, Shah SP, Prentice LM, Marra MA, Kiefer J, Zismann VL, et al. Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4. Nature Genetics. 46: 427-9. PMID 24658001 DOI: 10.1038/Ng.2928  0.402
2014 Mack SC, Witt H, Piro RM, Gu L, Zuyderduyn S, Stütz AM, Wang X, Gallo M, Garzia L, Zayne K, Zhang X, Ramaswamy V, Jäger N, Jones DT, Sill M, ... ... Marra MA, et al. Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. Nature. 506: 445-50. PMID 24553142 DOI: 10.1038/Nature13108  0.582
2014 Zovoilis A, Mungall AJ, Moore R, Varhol R, Chu A, Wong T, Marra M, Jones SJ. The expression level of small non-coding RNAs derived from the first exon of protein-coding genes is predictive of cancer status. Embo Reports. 15: 402-10. PMID 24534129 DOI: 10.1002/Embr.201337950  0.378
2014 Gunawardana J, Chan FC, Telenius A, Woolcock B, Kridel R, Tan KL, Ben-Neriah S, Mottok A, Lim RS, Boyle M, Rogic S, Rimsza LM, Guiter C, Leroy K, Gaulard P, ... ... Marra MA, et al. Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma. Nature Genetics. 46: 329-35. PMID 24531327 DOI: 10.1038/Ng.2900  0.472
2014 Weinstein JN, Akbani R, Broom BM, Wang W, Verhaak RGW, McConkey D, Lerner S, Morgan M, Creighton CJ, Smith C, Cherniack AD, Kim J, Pedamallu CS, Noble MS, Al-Ahmadie HA, ... ... Marra MA, et al. Comprehensive molecular characterization of urothelial bladder carcinoma Nature. 507: 315-322. PMID 24476821 DOI: 10.1038/Nature12965  0.696
2014 Johnson BE, Mazor T, Hong C, Barnes M, Aihara K, McLean CY, Fouse SD, Yamamoto S, Ueda H, Tatsuno K, Asthana S, Jalbert LE, Nelson SJ, Bollen AW, Gustafson WC, ... ... Marra MA, et al. Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma. Science (New York, N.Y.). 343: 189-93. PMID 24336570 DOI: 10.1126/Science.1239947  0.395
2014 Huse JT, Wallace M, Aldape KD, Berger MS, Bettegowda C, Brat DJ, Cahill DP, Cloughesy T, Haas-Kogan DA, Marra M, Miller CR, Nelson SJ, Salama SR, Soffietti R, Wen PY, et al. Where are we now? And where are we going? A report from the Accelerate Brain Cancer Cure (ABC2) low-grade glioma research workshop. Neuro-Oncology. 16: 173-8. PMID 24305708 DOI: 10.1093/Neuonc/Not229  0.337
2014 Tucker T, Zahir FR, Griffith M, Delaney A, Chai D, Tsang E, Lemyre E, Dobrzeniecka S, Marra M, Eydoux P, Langlois S, Hamdan FF, Michaud JL, Friedman JM. Single exon-resolution targeted chromosomal microarray analysis of known and candidate intellectual disability genes. European Journal of Human Genetics : Ejhg. 22: 792-800. PMID 24253858 DOI: 10.1038/Ejhg.2013.248  0.596
2014 Baxter SD, Lim HJ, Shen Y, Laskin JJ, Renouf DJ, Yip S, Huntsman D, Chia SKL, Li Y, Kasaian K, Eirew P, Leelakumari S, Ma Y, Aparicio S, Jones S, ... Marra M, et al. Whole-genome DNA and RNA sequencing in patients with metastatic colorectal cancer (mCRC). Journal of Clinical Oncology. 32. DOI: 10.1200/Jco.2014.32.15_Suppl.E22078  0.432
2014 Lim HJ, Shen Y, Laskin JJ, Gelmon KA, Renouf DJ, Sun S, Yip S, Huntsman D, Tinker A, Ho C, Chia SKL, Li Y, Kasaian K, Eirew P, Leelakumari S, ... ... Marra M, et al. The use of whole-genome sequencing in therapeutic for decision making in patients with advanced malignancies. Journal of Clinical Oncology. 32: 11026-11026. DOI: 10.1200/Jco.2014.32.15_Suppl.11026  0.348
2014 Ennishi D, Hoffer C, Shulha H, Mottok A, Farinha P, Chan FC, Meissner B, Boyle M, Ben-Neriah S, Morin RD, Marra MA, Savage KJ, Sehn LH, Connors JM, Steidl C, et al. Clinical Significance of Genetic Aberrations in Diffuse Large B Cell Lymphoma Blood. 124: 703-703. DOI: 10.1182/Blood.V124.21.703.703  0.682
2014 Totten S, Gaucher D, Morin RD, Assouline S, Connors JM, Marra MA, Scott DW, Gascoyne RD, Pelletier J, Mann KK, Johnson N. FAS Mutations Accelerate Lymphoma Growth and Induce Therapeutic Resistance Blood. 124: 3018-3018. DOI: 10.1182/Blood.V124.21.3018.3018  0.609
2014 Bashashati A, Anglesio M, Wang Y, Ha G, Senz J, Yang W, Kalloger S, Prentice L, Yanagida S, Salamanca C, Soukhatcheva G, Karnezis A, Chang H, Hirst M, Mes-Mason A, ... ... Marra M, et al. Abstract LB-312: The somatic mutational landscape of ovarian clear cell carcinoma and its precursor lesions Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-312  0.449
2014 Ramos P, Karnezis A, Craig D, Sekulic A, Russell M, Hendricks W, Barrett M, Shumansky K, Yang Y, Shah S, Prentice L, Marra M, Kiefer J, Zismann V, McEachron T, et al. Abstract LB-202: The rare, highly malignant small cell carcinoma of the ovary displays common inactivating germline and somatic mutations in the tumor suppressor SMARCA4 Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-202  0.439
2014 Johnson N, Gaucher D, Morin R, Gascoyne R, Connors J, Marra M, Pelletier J, Rigsby H, Mann K. Abstract 959: FAS mutations induce therapeutic resistance in non-Hodgkin lymphomas Cancer Research. 74: 959-959. DOI: 10.1158/1538-7445.Am2014-959  0.599
2014 Kasaian K, Shen Y, Leelakumari S, Eirew P, Li YY, Pleasance E, Corbett R, Mungall KL, Schein J, Mungall AJ, Zhao Y, Moore RA, Yip S, Gelmon K, Lim H, ... ... Marra MA, et al. Abstract 5340: Bioinformatic analyses approaches for personalized oncogenomics Cancer Research. 74: 5340-5340. DOI: 10.1158/1538-7445.Am2014-5340  0.458
2014 Laskin JJ, Shen Y, Lim H, Gelmon KA, Renouf D, Yip S, Huntsman D, Tinker A, Ho C, Chia S, Li Y, Kasaian K, Eirew P, Leelakumari S, Moore R, ... ... Marra M, et al. Abstract 4283: Whole genome sequencing is superior to cancer panels to aid in decision-making in patients with advanced malignancies Cancer Research. 74: 4283-4283. DOI: 10.1158/1538-7445.Am2014-4283  0.44
2014 Crews LA, Jiang Q, Zipeto MA, Court AC, Barrett CL, Marra MA, Frazer KA, Jamieson CHM. Abstract 375: A novel diagnostic assay for detection of primate-specific RNA editing events in leukemia stem cells Cancer Research. 74: 375-375. DOI: 10.1158/1538-7445.Am2014-375  0.326
2014 Chun HE, Zhu K, Qian JQ, Mungall KL, Ma Y, Zhao Y, Mungall AJ, Moore RA, Schein JE, Gerhard DS, Perlman EJ, Marra MA. Abstract 3087: Whole genome sequencing of rhabdoid tumors of the kidney Cancer Research. 74: 3087-3087. DOI: 10.1158/1538-7445.Am2014-3087  0.508
2014 Chen WC, Yuan JS, Mbong N, Popescu AC, Xing Y, Gerhard G, Zhang W, Ma Y, Moore R, Marra M, Minden MD, Hogge DE, Guidos C, Dick JE, Wang JCY. Abstract 2914: Phosphoproteomic and transcriptional biomarkers predict response to SAR302503, a JAK2 inhibitor, in human acute myeloid leukemia preclinical models Cancer Research. 74: 2914-2914. DOI: 10.1158/1538-7445.Am2014-2914  0.349
2014 Remke M, Jorgensen FMG, Morrissy AS, Ramaswamy V, Jones DTW, Marra M, Packer R, Bouffet E, Pfister SM, Jabado N, Taylor MD. GE-28 * INTEGRATED GENOMICS DEMONSTRATE RELATIVE SPATIAL HOMOGENEITY IN PEDIATRIC BRAIN TUMORS Neuro-Oncology. 16: v102-v102. DOI: 10.1093/Neuonc/Nou256.27  0.356
2014 Morrissy S, Garzia L, Remke M, Ramaswamy V, Jorgensen F, Wu X, Shah S, Ma Y, Mungall K, Meter TV, Cho Y, Collins P, MacDonald T, Li X, Moore R, ... ... Marra M, et al. Ge-21Drastic Genomic Divergence Of Recurrent Medulloblastoma Invalidates Targeted Therapies Discovered At Diagnosis. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou256.20  0.394
2014 Kaplan D, Grinshtein N, Rioseco C, Luchman A, Datti A, Aman A, Uehling D, Prakesch M, Wrana J, Cairncross G, Shen Y, Jones S, Marra M, Senger D, Robbins S, et al. COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS AND NOVEL TARGETS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS Neuro-Oncology. 16: iii20-iii20. DOI: 10.1093/Neuonc/Nou206.72  0.318
2014 Ramos P, Karnezis AN, Craig DW, Sekulic A, Russel ML, Hendricks WPD, Corneveaux JJ, Barrett MT, Shumansky K, Yang Y, Shah SP, Prentice LM, Marra MA, Kiefer J, Zismann VL, et al. Corrigendum: Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4 Nature Genetics. 46: 759-759. DOI: 10.1038/Ng0714-759A  0.355
2014 Brennan C, Verhaak R, McKenna A, Campos B, Noushmehr H, Salama S, Zheng S, Chakravarty D, Sanborn J, Berman S, Beroukhim R, Bernard B, Wu C, Genovese G, Shmulevich I, ... ... Marra M, et al. The Somatic Genomic Landscape of Glioblastoma Cell. 157: 753. DOI: 10.1016/J.Cell.2014.04.004  0.528
2013 Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, ... ... Marra M, et al. The somatic genomic landscape of glioblastoma. Cell. 155: 462-77. PMID 24120142 DOI: 10.1016/J.Cell.2013.09.034  0.609
2013 Bosdet IE, Docking TR, Butterfield YS, Mungall AJ, Zeng T, Coope RJ, Yorida E, Chow K, Bala M, Young SS, Hirst M, Birol I, Moore RA, Jones SJ, Marra MA, et al. A clinically validated diagnostic second-generation sequencing assay for detection of hereditary BRCA1 and BRCA2 mutations. The Journal of Molecular Diagnostics : Jmd. 15: 796-809. PMID 24094589 DOI: 10.1016/J.Jmoldx.2013.07.004  0.741
2013 Stevens M, Cheng JB, Li D, Xie M, Hong C, Maire CL, Ligon KL, Hirst M, Marra MA, Costello JF, Wang T. Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods. Genome Research. 23: 1541-53. PMID 23804401 DOI: 10.1101/Gr.152231.112  0.377
2013 Zhang B, Zhou Y, Lin N, Lowdon RF, Hong C, Nagarajan RP, Cheng JB, Li D, Stevens M, Lee HJ, Xing X, Zhou J, Sundaram V, Elliott G, Gu J, ... ... Marra MA, et al. Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm. Genome Research. 23: 1522-40. PMID 23804400 DOI: 10.1101/Gr.156539.113  0.314
2013 Bashashati A, Ha G, Tone A, Ding J, Prentice LM, Roth A, Rosner J, Shumansky K, Kalloger S, Senz J, Yang W, McConechy M, Melnyk N, Anglesio M, Luk MT, ... ... Marra MA, et al. Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling. The Journal of Pathology. 231: 21-34. PMID 23780408 DOI: 10.1002/Path.4230  0.471
2013 Xie M, Hong C, Zhang B, Lowdon RF, Xing X, Li D, Zhou X, Lee HJ, Maire CL, Ligon KL, Gascard P, Sigaroudinia M, Tlsty TD, Kadlecek T, Weiss A, ... ... Marra MA, et al. DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape. Nature Genetics. 45: 836-41. PMID 23708189 DOI: 10.1038/Ng.2649  0.349
2013 Vojvodic M, Hansford LM, Morozova O, Blakely KM, Taylor P, Fathers KE, Moffat J, Marra M, Smith KM, Moran MF, Kaplan DR. A phosphoproteomics approach to identify candidate kinase inhibitor pathway targets in lymphoma-like primary cell lines. Current Drug Discovery Technologies. 10: 283-304. PMID 23701117 DOI: 10.2174/15701638113109990001  0.681
2013 Morin RD, Mungall K, Pleasance E, Mungall AJ, Goya R, Huff RD, Scott DW, Ding J, Roth A, Chiu R, Corbett RD, Chan FC, Mendez-Lago M, Trinh DL, Bolger-Munro M, ... ... Marra MA, et al. Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing. Blood. 122: 1256-65. PMID 23699601 DOI: 10.1182/Blood-2013-02-483727  0.852
2013 Ley TJ, Miller C, Ding L, Raphael BJ, Mungall AJ, Robertson G, Hoadley K, Triche TJ, Laird PW, Baty JD, Fulton LL, Fulton R, Heath SE, Kalicki-Veizer J, Kandoth C, ... ... Marra MA, et al. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia New England Journal of Medicine. 368: 2059-2074. PMID 23634996 DOI: 10.1056/Nejmoa1301689  0.382
2013 Kasaian K, Wiseman SM, Thiessen N, Mungall KL, Corbett RD, Qian JQ, Nip KM, He A, Tse K, Chuah E, Varhol RJ, Pandoh P, McDonald H, Zeng T, Tam A, ... ... Marra MA, et al. Complete genomic landscape of a recurring sporadic parathyroid carcinoma. The Journal of Pathology. 230: 249-60. PMID 23616356 DOI: 10.1002/Path.4203  0.454
2013 Mwenifumbo JC, Marra MA. Cancer genome-sequencing study design Nature Reviews Genetics. 14: 321-332. PMID 23594910 DOI: 10.1038/Nrg3445  0.383
2013 Trinh DL, Scott DW, Morin RD, Mendez-Lago M, An J, Jones SJ, Mungall AJ, Zhao Y, Schein J, Steidl C, Connors JM, Gascoyne RD, Marra MA. Analysis of FOXO1 mutations in diffuse large B-cell lymphoma. Blood. 121: 3666-74. PMID 23460611 DOI: 10.1182/Blood-2013-01-479865  0.63
2013 Nolte SM, Venugopal C, McFarlane N, Morozova O, Hallett RM, O'Farrell E, Manoranjan B, Murty NK, Klurfan P, Kachur E, Provias JP, Farrokhyar F, Hassell JA, Marra M, Singh SK. A cancer stem cell model for studying brain metastases from primary lung cancer Journal of the National Cancer Institute. 105: 551-562. PMID 23418195 DOI: 10.1093/Jnci/Djt022  0.664
2013 Meissner B, Kridel R, Lim RS, Rogic S, Tse K, Scott DW, Moore R, Mungall AJ, Marra MA, Connors JM, Steidl C, Gascoyne RD. The E3 ubiquitin ligase UBR5 is recurrently mutated in mantle cell lymphoma. Blood. 121: 3161-4. PMID 23407552 DOI: 10.1182/Blood-2013-01-478834  0.42
2013 Pugh TJ, Morozova O, Attiyeh EF, Asgharzadeh S, Wei JS, Auclair D, Carter SL, Cibulskis K, Hanna M, Kiezun A, Kim J, Lawrence MS, Lichenstein L, McKenna A, Pedamallu CS, ... ... Marra MA, et al. The genetic landscape of high-risk neuroblastoma. Nature Genetics. 45: 279-84. PMID 23334666 DOI: 10.1038/Ng.2529  0.816
2013 Goff DJ, Court Recart A, Sadarangani A, Chun HJ, Barrett CL, Krajewska M, Leu H, Low-Marchelli J, Ma W, Shih AY, Wei J, Zhai D, Geron I, Pu M, Bao L, ... ... Marra M, et al. A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. Cell Stem Cell. 12: 316-28. PMID 23333150 DOI: 10.1016/J.Stem.2012.12.011  0.339
2013 Jiang Q, Crews LA, Barrett CL, Chun HJ, Court AC, Isquith JM, Zipeto MA, Goff DJ, Minden M, Sadarangani A, Rusert JM, Dao KH, Morris SR, Goldstein LS, Marra MA, et al. ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 110: 1041-6. PMID 23275297 DOI: 10.1073/Pnas.1213021110  0.372
2013 Dubuc AM, Remke M, Korshunov A, Northcott PA, Zhan SH, Mendez-Lago M, Kool M, Jones DT, Unterberger A, Morrissy AS, Shih D, Peacock J, Ramaswamy V, Rolider A, Wang X, ... ... Marra MA, et al. Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma. Acta Neuropathologica. 125: 373-84. PMID 23184418 DOI: 10.1007/S00401-012-1070-9  0.419
2013 Chand D, Yamazaki Y, Ruuth K, Schönherr C, Martinsson T, Kogner P, Attiyeh EF, Maris J, Morozova O, Marra MA, Ohira M, Nakagawara A, Sandström PE, Palmer RH, Hallberg B. Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma. Disease Models & Mechanisms. 6: 373-82. PMID 23104988 DOI: 10.1242/Dmm.010348  0.713
2013 Griffith M, Mwenifumbo JC, Cheung PY, Paul JE, Pugh TJ, Tang MJ, Chittaranjan S, Morin RD, Asano JK, Ally AA, Miao L, Lee A, Chan SY, Taylor G, Severson T, ... ... Marra MA, et al. Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer. The Pharmacogenomics Journal. 13: 148-58. PMID 22249354 DOI: 10.1038/Tpj.2011.65  0.765
2013 Peixoto RD, Li Y, Pleasance E, Yip S, Zhao Y, Schein J, Shen Y, Lim HJ, Renouf DJ, Gelmon KA, Huntsman D, Jones S, Marra M, Laskin JJ. A case of the utilization of genomic information in the management of metastatic colorectal cancer. Journal of Clinical Oncology. 31: 444-444. DOI: 10.1200/Jco.2013.31.4_Suppl.444  0.413
2013 Laskin JJ, Lim HJ, Gelmon KA, Ho C, Renouf DJ, Yip S, Huntsman D, Tinker A, Pleasance E, Li Y, Shen Y, Kasaian K, Corbett R, Mungall K, Mungall A, ... ... Marra M, et al. Practical application of whole genome and transcriptome tumour analysis to guide chemotherapy decision-making for patients with advanced cancers. Journal of Clinical Oncology. 31. DOI: 10.1200/Jco.2013.31.15_Suppl.E22020  0.398
2013 Sloma I, Mitjavila-Garcia MT, Feraud O, Oudrhiri N, Tosca L, El Marsafy S, Gobbo E, Divers D, Proust A, Griscelli F, Tachdjian G, Marra MA, Eaves CJ, Bennaceur-Griscelli A, Turhan AG. Whole Genome Sequencing Of Chronic Myeloid Leukemia (CML)-Derived Induced Pluripotent Stem Cells (iPSC) Reveals Faithful Genocopying Of Highly Mutated Primary Leukemic Cells Blood. 122: 514-514. DOI: 10.1182/Blood.V122.21.514.514  0.47
2013 Ennishi D, Chan FC, Scott DW, Hother C, Meissner B, Boyle M, Morin RD, Sehn LH, Marra MA, Connors JM, Steidl C, Gascoyne RD. Genetic Alterations In Immune Cell Crosstalk Genes In Diffuse Large B-Cell Lymphoma Predict Survival Blood. 122: 500-500. DOI: 10.1182/Blood.V122.21.500.500  0.642
2013 Berg T, Thoene S, Yap D, Wee T, Schoeler N, Rosten P, Lim E, Bilenky M, Mungall AJ, Oellerich T, Umlandt P, Salmi A, Chang H, Yue L, Lai D, ... ... Marra MA, et al. Characterization Of The Effects Of Mutated EZH2 On Expression and Epigenome In a Mouse Lymphoma Model Blood. 122: 346-346. DOI: 10.1182/Blood.V122.21.346.346  0.666
2013 Gunawardana J, Chan FC, Telenius A, Woolcock BW, Kridel R, Tan KL, Ben Neriah S, Lim RS, Rogic S, Boyle M, Guiter C, Leroy K, Haioun C, Rimsza LM, Gaulard P, ... ... Marra MA, et al. Protein Tyrosine Phosphatase Type-1 (PTPN1) Is Frequently Mutated In Primary Mediastinal B Cell Lymphoma and Hodgkin Lymphoma Blood. 122: 242-242. DOI: 10.1182/Blood.V122.21.242.242  0.473
2013 Court Recart AC, Sadarangani A, Chun E, Mason CN, Jiang Q, Barrett CL, Wall R, Goff DJ, Geron I, Shih A, Leu HS, Ma W, Minden MD, Frazer KA, Marra MA, et al. Inhibition Of Inflammation Driven Leukemia Stem Cell Self-Renewal With a Selective JAK2 Antagonist Blood. 122: 1481-1481. DOI: 10.1182/Blood.V122.21.1481.1481  0.347
2013 Laskin JJ, Gelmon K, Lim H, Renouf D, Yip S, Huntsman D, Tinker A, Ho C, Pleasance ED, Li Y, Shen Y, Kasaian K, Corbett R, Mungall K, Zhao Y, ... ... Marra M, et al. Abstract LB-173: Genome analysis informs chemotherapy decision-making in patients with advanced malignancies. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-173  0.425
2013 Wood AC, Pugh TJ, Morozova O, Koster J, Molenaar JJ, Pineros V, Bosse KR, Perin JC, Diskin S, Diamond MA, Marra M, Meyerson M, Versteeg R, Maris JM. Abstract 3804: Rare DNA variants are enriched at the BARD1 locus and likely influence neuroblastoma susceptibility. Cancer Research. 73: 3804-3804. DOI: 10.1158/1538-7445.Am2013-3804  0.692
2013 Jiang Q, Crews LA, Barrett CL, Court-Recart A, Goff D, Sadarangani A, Rusert J, Morris S, Goldstein L, Chun H, Marra M, Fraser K, Dao K, Minden M, Jamieson C. Abstract 247: ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Cancer Research. 73: 247-247. DOI: 10.1158/1538-7445.Am2013-247  0.374
2013 Adachi K, Sasaki H, Nagahisa S, Yoshida K, Hattori N, Nishiyama Y, Kawase T, Hasegawa M, Abe M, Hirose Y, Alentorn A, Marie Y, Poggioli S, Alshehhi H, Boisselier B, ... ... Marra M, et al. OMICS AND PROGNSTIC MARKERS Neuro-Oncology. 15: iii136-iii155. DOI: 10.1093/Neuonc/Not183  0.422
2013 Morin RD, Marra M. Transcriptomics in the Age of Ultra High-Throughput Sequencing Genomic and Personalized Medicine. 1: 145-154. DOI: 10.1016/B978-0-12-382227-7.00012-4  0.508
2012 Khodabakhshi AH, Morin RD, Fejes AP, Mungall AJ, Mungall KL, Bolger-Munro M, Johnson NA, Connors JM, Gascoyne RD, Marra MA, Birol I, Jones SJM. Recurrent targets of aberrant somatic hypermutation in lymphoma Oncotarget. 3: 1308-1319. PMID 23131835 DOI: 10.18632/Oncotarget.653  0.646
2012 Cheng SW, Kuzyk MA, Moradian A, Ichu TA, Chang VC, Tien JF, Vollett SE, Griffith M, Marra MA, Morin GB. Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II. Molecular and Cellular Biology. 32: 4691-704. PMID 22988298 DOI: 10.1128/Mcb.06267-11  0.507
2012 Hammerman PS, Voet D, Lawrence MS, Jing R, Cibulskis K, Sivachenko A, Stojanov P, McKenna A, Lander ES, Gabriel S, Getz G, Imielinski M, Helman E, Hernandez B, Pho NH, ... ... Marra MA, et al. Comprehensive genomic characterization of squamous cell lung cancers Nature. 489: 519-525. PMID 22960745 DOI: 10.1038/Nature11404  0.571
2012 Wu C, Wyatt AW, McPherson A, Lin D, McConeghy BJ, Mo F, Shukin R, Lapuk AV, Jones SJ, Zhao Y, Marra MA, Gleave ME, Volik SV, Wang Y, Sahinalp SC, et al. Poly-gene fusion transcripts and chromothripsis in prostate cancer. Genes, Chromosomes & Cancer. 51: 1144-53. PMID 22927308 DOI: 10.1002/Gcc.21999  0.458
2012 Crisan A, Goya R, Ha G, Ding J, Prentice LM, Oloumi A, Senz J, Zeng T, Tse K, Delaney A, Marra MA, Huntsman DG, Hirst M, Aparicio S, Shah S. Mutation discovery in regions of segmental cancer genome amplifications with CoNAn-SNV: a mixture model for next generation sequencing of tumors. Plos One. 7: e41551. PMID 22916110 DOI: 10.1371/Journal.Pone.0041551  0.807
2012 Roberts KG, Morin RD, Zhang J, Hirst M, Zhao Y, Su X, Chen SC, Payne-Turner D, Churchman ML, Harvey RC, Chen X, Kasap C, Yan C, Becksfort J, Finney RP, ... ... Marra MA, et al. Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. Cancer Cell. 22: 153-66. PMID 22897847 DOI: 10.1016/J.Ccr.2012.06.005  0.611
2012 Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T, Stütz AM, Korshunov A, Reimand J, Schumacher SE, Beroukhim R, Ellison DW, Marshall CR, Lionel AC, Mack S, ... ... Marra MA, et al. Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature. 488: 49-56. PMID 22832581 DOI: 10.1038/Nature11327  0.508
2012 Vrljicak P, Cullum R, Xu E, Chang AC, Wederell ED, Bilenky M, Jones SJ, Marra MA, Karsan A, Hoodless PA. Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse. Plos One. 7: e40815. PMID 22815831 DOI: 10.1371/Journal.Pone.0040815  0.333
2012 Muzny DM, Bainbridge MN, Chang K, Dinh HH, Drummond JA, Fowler G, Kovar CL, Lewis LR, Morgan MB, Newsham IF, Reid JG, Santibanez J, Shinbrot E, Trevino LR, Wu YQ, ... ... Marra MA, et al. Comprehensive molecular characterization of human colon and rectal cancer Nature. 487: 330-337. PMID 22810696 DOI: 10.1038/Nature11252  0.481
2012 Blough MD, Al-Najjar M, Chesnelong C, Binding CE, Rogers AD, Luchman HA, Kelly JJ, Fliegel L, Morozova O, Yip S, Marra M, Weiss S, Chan JA, Cairncross JG. DNA hypermethylation and 1p Loss silence NHE-1 in oligodendroglioma. Annals of Neurology. 71: 845-9. PMID 22718548 DOI: 10.1002/Ana.23610  0.681
2012 Ha G, Roth A, Lai D, Bashashati A, Ding J, Goya R, Giuliany R, Rosner J, Oloumi A, Shumansky K, Chin SF, Turashvili G, Hirst M, Caldas C, Marra MA, et al. Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer. Genome Research. 22: 1995-2007. PMID 22637570 DOI: 10.1101/Gr.137570.112  0.817
2012 Chen K, Wallis JW, Kandoth C, Kalicki-Veizer JM, Mungall KL, Mungall AJ, Jones SJ, Marra MA, Ley TJ, Mardis ER, Wilson RK, Weinstein JN, Ding L. BreakFusion: targeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data. Bioinformatics (Oxford, England). 28: 1923-4. PMID 22563071 DOI: 10.1093/Bioinformatics/Bts272  0.369
2012 Lapuk AV, Wu C, Wyatt AW, McPherson A, McConeghy BJ, Brahmbhatt S, Mo F, Zoubeidi A, Anderson S, Bell RH, Haegert A, Shukin R, Wang Y, Fazli L, Hurtado-Coll A, ... ... Marra MA, et al. From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer. The Journal of Pathology. 227: 286-97. PMID 22553170 DOI: 10.1002/Path.4047  0.367
2012 Scott DW, Mungall KL, Ben-Neriah S, Rogic S, Morin RD, Slack GW, Tan KL, Chan FC, Lim RS, Connors JM, Marra MA, Mungall AJ, Steidl C, Gascoyne RD. TBL1XR1/TP63: a novel recurrent gene fusion in B-cell non-Hodgkin lymphoma. Blood. 119: 4949-52. PMID 22496164 DOI: 10.1182/Blood-2012-02-414441  0.63
2012 Shah SP, Roth A, Goya R, Oloumi A, Ha G, Zhao Y, Turashvili G, Ding J, Tse K, Haffari G, Bashashati A, Prentice LM, Khattra J, Burleigh A, Yap D, ... ... Marra MA, et al. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature. 486: 395-9. PMID 22495314 DOI: 10.1038/Nature10933  0.825
2012 Baradaran-Heravi A, Cho KS, Tolhuis B, Sanyal M, Morozova O, Morimoto M, Elizondo LI, Bridgewater D, Lubieniecka J, Beirnes K, Myung C, Leung D, Fam HK, Choi K, Huang Y, ... ... Marra MA, et al. Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression. Human Molecular Genetics. 21: 2572-87. PMID 22378147 DOI: 10.1093/Hmg/Dds083  0.721
2012 Dubuc AM, Morrissy AS, Kloosterhof NK, Northcott PA, Yu EP, Shih D, Peacock J, Grajkowska W, van Meter T, Eberhart CG, Pfister S, Marra MA, Weiss WA, Scherer SW, Rutka JT, et al. Subgroup-specific alternative splicing in medulloblastoma. Acta Neuropathologica. 123: 485-99. PMID 22358458 DOI: 10.1007/S00401-012-0959-7  0.355
2012 Wu C, Wyatt AW, Lapuk AV, McPherson A, McConeghy BJ, Bell RH, Anderson S, Haegert A, Brahmbhatt S, Shukin R, Mo F, Li E, Fazli L, Hurtado-Coll A, Jones EC, ... ... Marra MA, et al. Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer. The Journal of Pathology. 227: 53-61. PMID 22294438 DOI: 10.1002/Path.3987  0.428
2012 Roth A, Ding J, Morin R, Crisan A, Ha G, Giuliany R, Bashashati A, Hirst M, Turashvili G, Oloumi A, Marra MA, Aparicio S, Shah SP. JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data. Bioinformatics (Oxford, England). 28: 907-13. PMID 22285562 DOI: 10.1093/Bioinformatics/Bts053  0.653
2012 Chu JS, Johnsen RC, Chua SY, Tu D, Dennison M, Marra M, Jones SJ, Baillie DL, Rose AM. Allelic ratios and the mutational landscape reveal biologically significant heterozygous SNVs. Genetics. 190: 1225-33. PMID 22267497 DOI: 10.1534/Genetics.111.137208  0.79
2012 Collins CC, Volik SV, Lapuk AV, Wang Y, Gout PW, Wu C, Xue H, Cheng H, Haegert A, Bell RH, Brahmbhatt S, Anderson S, Fazli L, Hurtado-Coll A, Rubin MA, ... ... Marra M, et al. Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target. Molecular Cancer Therapeutics. 11: 775-83. PMID 22252602 DOI: 10.1158/1535-7163.Mct-11-0826  0.377
2012 Astanehe A, Finkbeiner MR, Krzywinski M, Fotovati A, Dhillon J, Berquin IM, Mills GB, Marra MA, Dunn SE. MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition. Oncogene. 31: 4434-46. PMID 22249268 DOI: 10.1038/Onc.2011.617  0.336
2012 Najafzadeh M, Lynd LD, Davis JC, Bryan S, Anis A, Marra M, Marra CA. Barriers to integrating personalized medicine into clinical practice: a best-worst scaling choice experiment. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 14: 520-6. PMID 22241089 DOI: 10.1038/Gim.2011.26  0.327
2012 Lee CH, Ou WB, Mariño-Enriquez A, Zhu M, Mayeda M, Wang Y, Guo X, Brunner AL, Amant F, French CA, West RB, McAlpine JN, Gilks CB, Yaffe MB, Prentice LM, ... ... Marra MA, et al. 14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma. Proceedings of the National Academy of Sciences of the United States of America. 109: 929-34. PMID 22223660 DOI: 10.1073/Pnas.1115528109  0.431
2012 Kridel R, Meissner B, Rogic S, Boyle M, Telenius A, Woolcock B, Gunawardana J, Jenkins C, Cochrane C, Ben-Neriah S, Tan K, Morin RD, Opat S, Sehn LH, Connors JM, ... Marra MA, et al. Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma. Blood. 119: 1963-71. PMID 22210878 DOI: 10.1182/Blood-2011-11-391474  0.654
2012 Schuetz JM, Johnson NA, Morin RD, Scott DW, Tan K, Ben-Nierah S, Boyle M, Slack GW, Marra MA, Connors JM, Brooks-Wilson AR, Gascoyne RD. BCL2 mutations in diffuse large B-cell lymphoma. Leukemia. 26: 1383-90. PMID 22189900 DOI: 10.1038/Leu.2011.378  0.645
2012 Heravi-Moussavi A, Anglesio MS, Cheng SW, Senz J, Yang W, Prentice L, Fejes AP, Chow C, Tone A, Kalloger SE, Hamel N, Roth A, Ha G, Wan AN, Maines-Bandiera S, ... ... Marra MA, et al. Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers. The New England Journal of Medicine. 366: 234-42. PMID 22187960 DOI: 10.1056/Nejmoa1102903  0.35
2012 Gibson WT, Hood RL, Zhan SH, Bulman DE, Fejes AP, Moore R, Mungall AJ, Eydoux P, Babul-Hirji R, An J, Marra MA, Chitayat D, Boycott KM, Weaver DD, et al. Mutations in EZH2 cause Weaver syndrome. American Journal of Human Genetics. 90: 110-8. PMID 22177091 DOI: 10.1016/J.Ajhg.2011.11.018  0.39
2012 Ding J, Bashashati A, Roth A, Oloumi A, Tse K, Zeng T, Haffari G, Hirst M, Marra MA, Condon A, Aparicio S, Shah SP. Feature-based classifiers for somatic mutation detection in tumour-normal paired sequencing data. Bioinformatics (Oxford, England). 28: 167-75. PMID 22084253 DOI: 10.1093/Bioinformatics/Btr629  0.445
2012 Yip S, Butterfield YS, Morozova O, Chittaranjan S, Blough MD, An J, Birol I, Chesnelong C, Chiu R, Chuah E, Corbett R, Docking R, Firme M, Hirst M, Jackman S, ... ... Marra MA, et al. Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers. The Journal of Pathology. 226: 7-16. PMID 22072542 DOI: 10.1002/Path.2995  0.73
2012 Northcott PA, Shih DJ, Remke M, Cho YJ, Kool M, Hawkins C, Eberhart CG, Dubuc A, Guettouche T, Cardentey Y, Bouffet E, Pomeroy SL, Marra M, Malkin D, Rutka JT, et al. Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples. Acta Neuropathologica. 123: 615-26. PMID 22057785 DOI: 10.1007/S00401-011-0899-7  0.328
2012 Recart ACC, Goff DJ, Sadarangani A, Mason CN, Shih AY, Wall R, Leu HS, Ma W, Chun H, Marra MA, Barrett CL, Frazer KA, Jamieson C. Combined JAK/STAT5A and BCR-ABL Inhibition Impairs Blast Crisis Chronic Myeloid Leukemia Stem Cell Self-Renewal Blood. 120: 910-910. DOI: 10.1182/Blood.V120.21.910.910  0.322
2012 Leu HS, Goff DJ, Low-Marchelli J, Recart ACC, Smith KM, Ma W, Sadarangani A, Shih AY, Wei J, Zhai D, Gotlib J, Minden MD, Martinelli G, Marra MA, Frazer KA, et al. Sabutoclax, a Novel Pan BCL2 Family Inhibitor, Sensitizes Dormant Blast Crisis Chronic Myeloid Leukemia Stem Cells to Dasatinib Blood. 120: 3739-3739. DOI: 10.1182/Blood.V120.21.3739.3739  0.324
2012 Chan FC, Ben-Neriah S, Lim R, Hu S, Rogic S, Johnson N, Morin RD, Ha G, Ding J, Scott DW, Sehn LH, Connors JM, Marra MA, Gascoyne RD, Shah SP, et al. Large-Scale High Resolution Integration of Copy Number and Gene Expression in DLBCL Reveals Focal and Frequent Deletions in Chromatin Modifying Genes with Outcome Correlation Blood. 120: 295-295. DOI: 10.1182/Blood.V120.21.295.295  0.649
2012 Jiang Q, Crews-Robertson L, Barrett CL, Chun H, Court-Recart AC, Goff DJ, Minden MD, Sadarangani A, Rusert J, Dao K, Morris SR, Goldstein LSB, Marra MA, Frazer KA, Jamieson C. The RNA Editase ADAR1 Promotes Malignant Progenitor Reprogramming in Chronic Myeloid Leukemia. Blood. 120: 2772-2772. DOI: 10.1182/Blood.V120.21.2772.2772  0.362
2012 Balaian L, Sadarangani A, Widhopf GF, Zhong R, Prussak C, Marra MA, Dick JE, Minden MD, Ball ED, Carson DA, Jamieson C, Kipps TJ. A Highly Selective Anti-ROR1 Monoclonal Antibody Inhibits Human Acute Myeloid Leukemia CD34+ Cell Survival and Self-Renewal. Blood. 120: 2560-2560. DOI: 10.1182/Blood.V120.21.2560.2560  0.328
2012 Johnson N, Gaucher D, Rigsby H, Morin RD, Connors JM, Marra M, Gascoyne RD. FAS Mutations Are Associated with Therapeutic Resistance in Follicular Lymphoma Blood. 120: 1549-1549. DOI: 10.1182/Blood.V120.21.1549.1549  0.634
2012 Koboldt DC, Fulton RS, McLellan MD, Schmidt H, Kalicki-Veizer J, McMichael JF, Fulton LL, Dooling DJ, Ding L, Mardis ER, Wilson RK, Ally A, Balasundaram M, Butterfield YSN, Carlsen R, ... ... Marra MA, et al. Comprehensive molecular portraits of human breast tumours Nature. 490: 61-70. DOI: 10.1038/Nature11412  0.551
2012 Mendez-Lago M, Morin R, Mungall A, Goya R, Trinh D, Corbett R, Rogic S, Gascoyne R, Connors J, Marra M. 567 Genomic Analysis of Non-Hodgkin Lymphomas Reveals Mutations in Chromatin Remodelling Genes European Journal of Cancer. 48: S135. DOI: 10.1016/S0959-8049(12)71226-1  0.833
2011 White AK, VanInsberghe M, Petriv OI, Hamidi M, Sikorski D, Marra MA, Piret J, Aparicio S, Hansen CL. High-throughput microfluidic single-cell RT-qPCR. Proceedings of the National Academy of Sciences of the United States of America. 108: 13999-4004. PMID 21808033 DOI: 10.1073/Pnas.1019446108  0.335
2011 Morin RD, Mendez-Lago M, Mungall AJ, Goya R, Mungall KL, Corbett RD, Johnson NA, Severson TM, Chiu R, Field M, Jackman S, Krzywinski M, Scott DW, Trinh DL, Tamura-Wells J, ... ... Marra MA, et al. Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma Nature. 476: 298-303. PMID 21796119 DOI: 10.1038/Nature10351  0.828
2011 Schrader KA, Heravi-Moussavi A, Waters PJ, Senz J, Whelan J, Ha G, Eydoux P, Nielsen T, Gallagher B, Oloumi A, Boyd N, Fernandez BA, Young TL, Jones SJ, Hirst M, ... ... Marra MA, et al. Using next-generation sequencing for the diagnosis of rare disorders: a family with retinitis pigmentosa and skeletal abnormalities. The Journal of Pathology. 225: 12-8. PMID 21792934 DOI: 10.1002/Path.2941  0.408
2011 Heuser M, Yun H, Berg T, Yung E, Argiropoulos B, Kuchenbauer F, Park G, Hamwi I, Palmqvist L, Lai CK, Leung M, Lin G, Chaturvedi A, Thakur BK, Iwasaki M, ... ... Marra M, et al. Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex. Cancer Cell. 20: 39-52. PMID 21741595 DOI: 10.1016/J.Ccr.2011.06.020  0.331
2011 Morrissy AS, Griffith M, Marra MA. Extensive relationship between antisense transcription and alternative splicing in the human genome. Genome Research. 21: 1203-12. PMID 21719572 DOI: 10.1101/Gr.113431.110  0.589
2011 O'Connor MD, Wederell E, Robertson G, Delaney A, Morozova O, Poon SS, Yap D, Fee J, Zhao Y, McDonald H, Zeng T, Hirst M, Marra MA, Aparicio SA, Eaves CJ. Retinoblastoma-binding proteins 4 and 9 are important for human pluripotent stem cell maintenance. Experimental Hematology. 39: 866-79.e1. PMID 21689726 DOI: 10.1016/J.Exphem.2011.05.008  0.675
2011 Kuchenbauer F, Mah SM, Heuser M, McPherson A, Rüschmann J, Rouhi A, Berg T, Bullinger L, Argiropoulos B, Morin RD, Lai D, Starczynowski DT, Karsan A, Eaves CJ, Watahiki A, ... ... Marra MA, et al. Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells. Blood. 118: 3350-8. PMID 21628414 DOI: 10.1182/Blood-2010-10-312454  0.517
2011 McPherson A, Hormozdiari F, Zayed A, Giuliany R, Ha G, Sun MG, Griffith M, Heravi Moussavi A, Senz J, Melnyk N, Pacheco M, Marra MA, Hirst M, Nielsen TO, Sahinalp SC, et al. deFuse: an algorithm for gene fusion discovery in tumor RNA-Seq data. Plos Computational Biology. 7: e1001138. PMID 21625565 DOI: 10.1371/Journal.Pcbi.1001138  0.629
2011 Tucker T, Montpetit A, Chai D, Chan S, Chénier S, Coe BP, Delaney A, Eydoux P, Lam WL, Langlois S, Lemyre E, Marra M, Qian H, Rouleau GA, Vincent D, et al. Comparison of genome-wide array genomic hybridization platforms for the detection of copy number variants in idiopathic mental retardation. Bmc Medical Genomics. 4: 25. PMID 21439053 DOI: 10.1186/1755-8794-4-25  0.332
2011 Steidl C, Shah SP, Woolcock BW, Rui L, Kawahara M, Farinha P, Johnson NA, Zhao Y, Telenius A, Neriah SB, McPherson A, Meissner B, Okoye UC, Diepstra A, van den Berg A, ... ... Marra MA, et al. MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers. Nature. 471: 377-81. PMID 21368758 DOI: 10.1038/Nature09754  0.412
2011 Blahnik KR, Dou L, Echipare L, Iyengar S, O'Geen H, Sanchez E, Zhao Y, Marra MA, Hirst M, Costello JF, Korf I, Farnham PJ. Characterization of the contradictory chromatin signatures at the 3' exons of zinc finger genes. Plos One. 6: e17121. PMID 21347206 DOI: 10.1371/Journal.Pone.0017121  0.378
2011 D'Souza CA, Kronstad JW, Taylor G, Warren R, Yuen M, Hu G, Jung WH, Sham A, Kidd SE, Tangen K, Lee N, Zeilmaker T, Sawkins J, McVicker G, Shah S, ... ... Marra M, et al. Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts. Mbio. 2: e00342-10. PMID 21304167 DOI: 10.1128/Mbio.00342-10  0.372
2011 DiGuistini S, Wang Y, Liao NY, Taylor G, Tanguay P, Feau N, Henrissat B, Chan SK, Hesse-Orce U, Alamouti SM, Tsui CK, Docking RT, Levasseur A, Haridas S, Robertson G, ... ... Marra MA, et al. Genome and transcriptome analyses of the mountain pine beetle-fungal symbiont Grosmannia clavigera, a lodgepole pine pathogen. Proceedings of the National Academy of Sciences of the United States of America. 108: 2504-9. PMID 21262841 DOI: 10.1073/Pnas.1011289108  0.392
2011 Yap DB, Chu J, Berg T, Schapira M, Cheng SW, Moradian A, Morin RD, Mungall AJ, Meissner B, Boyle M, Marquez VE, Marra MA, Gascoyne RD, Humphries RK, Arrowsmith CH, et al. Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation. Blood. 117: 2451-9. PMID 21190999 DOI: 10.1182/Blood-2010-11-321208  0.616
2011 Starczynowski DT, Morin R, McPherson A, Lam J, Chari R, Wegrzyn J, Kuchenbauer F, Hirst M, Tohyama K, Humphries RK, Lam WL, Marra M, Karsan A. Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations. Blood. 117: 595-607. PMID 20962326 DOI: 10.1182/Blood-2010-03-277012  0.566
2011 Yip S, Butterfield Y, Morozova O, Blough M, Chittaranjan S, Maslova A, Corbett R, Chan J, Cairncross J, Marra M. Next generation sequencing of oligodendroglioma – a work in progress F1000research. 2. DOI: 10.7490/F1000Research.1984.1  0.313
2011 Roberts KG, Morin RD, Zhang J, Hirst M, Harvey RC, Kasap C, Chen X, Edmonson M, Chen I, Shah N, Devidas M, Reaman GH, Smith MA, Pui C, Downing JR, ... ... Marra MA, et al. Novel Chromosomal Rearrangements and Sequence Mutations in High-Risk Ph-Like Acute Lymphoblastic Leukemia Blood. 118: 67-67. DOI: 10.1182/Blood.V118.21.67.67  0.656
2011 Berg T, Yap D, Thoene S, Wee T, Schoeler N, Umlandt P, Chang H, Yue L, Lai D, Cheng G, Morin RD, Hirst M, Marra MA, Morin GB, Gascoyne RD, et al. Mutated EZH2 Collaborates with Myc in Inducing Lymphoma in a Mouse Model Blood. 118: 227-227. DOI: 10.1182/Blood.V118.21.227.227  0.609
2011 Recart ACC, Sadarangani A, Goff D, Shih AY, Wall R, Leu H, Ma W, Barrett CL, Frazer KA, Chun E, Marra MA, Jamieson C. Combination Targeted Therapy to Impair Self-Renewal Capacity of Human Blast Crisis Leukemia Stem Cells Blood. 118: 1693-1693. DOI: 10.1182/Blood.V118.21.1693.1693  0.302
2011 Morozova O, Birol I, Corbett R, Mungall K, Attiyeh EF, Asgharzadeh S, Zhao Y, Moore RA, Hirst M, Jones S, Hogarty MD, Diskin S, Mosse YP, Diamond M, Sposto R, ... ... Marra MA, et al. Abstract 926: Whole genome and transcriptome sequencing defines the spectrum of somatic changes in high-risk neuroblastoma Cancer Research. 71: 926-926. DOI: 10.1158/1538-7445.Am2011-926  0.774
2010 Hirst M, Marra MA. Next generation sequencing based approaches to epigenomics Briefings in Functional Genomics. 9: 455-465. PMID 21266347 DOI: 10.1093/Bfgp/Elq035  0.324
2010 McLarren KW, Severson TM, du Souich C, Stockton DW, Kratz LE, Cunningham D, Hendson G, Morin RD, Wu D, Paul JE, An J, Nelson TN, Chou A, DeBarber AE, Merkens LS, ... ... Marra MA, et al. Hypomorphic temperature-sensitive alleles of NSDHL cause CK syndrome. American Journal of Human Genetics. 87: 905-14. PMID 21129721 DOI: 10.1016/J.Ajhg.2010.11.004  0.568
2010 Cerchietti LC, Hatzi K, Caldas-Lopes E, Yang SN, Figueroa ME, Morin RD, Hirst M, Mendez L, Shaknovich R, Cole PA, Bhalla K, Gascoyne RD, Marra M, Chiosis G, Melnick A. BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy. The Journal of Clinical Investigation. 120: 4569-82. PMID 21041953 DOI: 10.1172/Jci42869  0.597
2010 Law MJ, Lower KM, Voon HP, Hughes JR, Garrick D, Viprakasit V, Mitson M, De Gobbi M, Marra M, Morris A, Abbott A, Wilder SP, Taylor S, Santos GM, Cross J, et al. ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner. Cell. 143: 367-78. PMID 21029860 DOI: 10.1016/J.Cell.2010.09.023  0.403
2010 Wiegand KC, Shah SP, Al-Agha OM, Zhao Y, Tse K, Zeng T, Senz J, McConechy MK, Anglesio MS, Kalloger SE, Yang W, Heravi-Moussavi A, Giuliany R, Chow C, Fee J, ... ... Marra MA, et al. ARID1A mutations in endometriosis-associated ovarian carcinomas. The New England Journal of Medicine. 363: 1532-43. PMID 20942669 DOI: 10.1056/Nejmoa1008433  0.367
2010 Robertson G, Schein J, Chiu R, Corbett R, Field M, Jackman SD, Mungall K, Lee S, Okada HM, Qian JQ, Griffith M, Raymond A, Thiessen N, Cezard T, Butterfield YS, ... ... Marra MA, et al. De novo assembly and analysis of RNA-seq data. Nature Methods. 7: 909-12. PMID 20935650 DOI: 10.1038/Nmeth.1517  0.542
2010 Cheung KJ, Johnson NA, Affleck JG, Severson T, Steidl C, Ben-Neriah S, Schein J, Morin RD, Moore R, Shah SP, Qian H, Paul JE, Telenius A, Relander T, Lam W, ... ... Marra MA, et al. Acquired TNFRSF14 mutations in follicular lymphoma are associated with worse prognosis. Cancer Research. 70: 9166-74. PMID 20884631 DOI: 10.1158/0008-5472.Can-10-2460  0.645
2010 Romanuik TL, Wang G, Morozova O, Delaney A, Marra MA, Sadar MD. LNCaP Atlas: gene expression associated with in vivo progression to castration-recurrent prostate cancer. Bmc Medical Genomics. 3: 43. PMID 20868494 DOI: 10.1186/1755-8794-3-43  0.668
2010 Harris RA, Wang T, Coarfa C, Nagarajan RP, Hong C, Downey SL, Johnson BE, Fouse SD, Delaney A, Zhao Y, Olshen A, Ballinger T, Zhou X, Forsberg KJ, Gu J, ... ... Marra MA, et al. Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nature Biotechnology. 28: 1097-105. PMID 20852635 DOI: 10.1038/Nbt.1682  0.349
2010 Jinno H, Morozova O, Jones KL, Biernaskie JA, Paris M, Hosokawa R, Rudnicki MA, Chai Y, Rossi F, Marra MA, Miller FD. Convergent genesis of an adult neural crest-like dermal stem cell from distinct developmental origins. Stem Cells (Dayton, Ohio). 28: 2027-40. PMID 20848654 DOI: 10.1002/Stem.525  0.685
2010 Griffith M, Griffith OL, Mwenifumbo J, Goya R, Morrissy AS, Morin RD, Corbett R, Tang MJ, Hou YC, Pugh TJ, Robertson G, Chittaranjan S, Ally A, Asano JK, Chan SY, ... ... Marra MA, et al. Alternative expression analysis by RNA sequencing. Nature Methods. 7: 843-7. PMID 20835245 DOI: 10.1038/Nmeth.1503  0.808
2010 Smith KM, Datti A, Fujitani M, Grinshtein N, Zhang L, Morozova O, Blakely KM, Rotenberg SA, Hansford LM, Miller FD, Yeger H, Irwin MS, Moffat J, Marra MA, Baruchel S, et al. Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens. Embo Molecular Medicine. 2: 371-84. PMID 20721990 DOI: 10.1002/Emmm.201000093  0.69
2010 Jones SJ, Laskin J, Li YY, Griffith OL, An J, Bilenky M, Butterfield YS, Cezard T, Chuah E, Corbett R, Fejes AP, Griffith M, Yee J, Martin M, Mayo M, ... ... Marra MA, et al. Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors. Genome Biology. 11: R82. PMID 20696054 DOI: 10.1186/Gb-2010-11-8-R82  0.741
2010 Morin RD, Zhao Y, Prabhu AL, Dhalla N, McDonald H, Pandoh P, Tam A, Zeng T, Hirst M, Marra M. Preparation and analysis of microRNA libraries using the Illumina massively parallel sequencing technology. Methods in Molecular Biology (Clifton, N.J.). 650: 173-99. PMID 20686952 DOI: 10.1007/978-1-60761-769-3_14  0.61
2010 Morozova O, Vojvodic M, Grinshtein N, Hansford LM, Blakely KM, Maslova A, Hirst M, Cezard T, Morin RD, Moore R, Smith KM, Miller F, Taylor P, Thiessen N, Varhol R, ... ... Marra MA, et al. System-level analysis of neuroblastoma tumor-initiating cells implicates AURKB as a novel drug target for neuroblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4572-82. PMID 20651058 DOI: 10.1158/1078-0432.Ccr-10-0627  0.786
2010 Maunakea AK, Nagarajan RP, Bilenky M, Ballinger TJ, D'Souza C, Fouse SD, Johnson BE, Hong C, Nielsen C, Zhao Y, Turecki G, Delaney A, Varhol R, Thiessen N, Shchors K, ... ... Marra MA, et al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature. 466: 253-7. PMID 20613842 DOI: 10.1038/Nature09165  0.304
2010 Hoffman BG, Robertson G, Zavaglia B, Beach M, Cullum R, Lee S, Soukhatcheva G, Li L, Wederell ED, Thiessen N, Bilenky M, Cezard T, Tam A, Kamoh B, Birol I, ... ... Marra MA, et al. Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver. Genome Research. 20: 1037-51. PMID 20551221 DOI: 10.1101/Gr.104356.109  0.301
2010 Cheung KJ, Delaney A, Ben-Neriah S, Schein J, Lee T, Shah SP, Cheung D, Johnson NA, Mungall AJ, Telenius A, Lai B, Boyle M, Connors JM, Gascoyne RD, Marra MA, et al. High resolution analysis of follicular lymphoma genomes reveals somatic recurrent sites of copy-neutral loss of heterozygosity and copy number alterations that target single genes. Genes, Chromosomes & Cancer. 49: 669-81. PMID 20544841 DOI: 10.1002/Gcc.20780  0.381
2010 Flibotte S, Edgley ML, Chaudhry I, Taylor J, Neil SE, Rogula A, Zapf R, Hirst M, Butterfield Y, Jones SJ, Marra MA, Barstead RJ, Moerman DG. Whole-genome profiling of mutagenesis in Caenorhabditis elegans. Genetics. 185: 431-41. PMID 20439774 DOI: 10.1534/Genetics.110.116616  0.403
2010 Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bernabé RR, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, ... ... Marra M, ... ... Marra M, et al. International network of cancer genome projects. Nature. 464: 993-8. PMID 20393554 DOI: 10.1038/Nature08987  0.379
2010 Morrissy S, Zhao Y, Delaney A, Asano J, Dhalla N, Li I, McDonald H, Pandoh P, Prabhu AL, Tam A, Hirst M, Marra M. Digital gene expression by tag sequencing on the illumina genome analyzer. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 11.11.1-36. PMID 20373513 DOI: 10.1002/0471142905.Hg1111S65  0.415
2010 Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A. MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing. Molecular Human Reproduction. 16: 463-71. PMID 20215419 DOI: 10.1093/Molehr/Gaq017  0.56
2010 Rose AM, O'Neil NJ, Bilenky M, Butterfield YS, Malhis N, Flibotte S, Jones MR, Marra M, Baillie DL, Jones SJ. Genomic sequence of a mutant strain of Caenorhabditis elegans with an altered recombination pattern. Bmc Genomics. 11: 131. PMID 20178641 DOI: 10.1186/1471-2164-11-131  0.754
2010 Goya R, Sun MG, Morin RD, Leung G, Ha G, Wiegand KC, Senz J, Crisan A, Marra MA, Hirst M, Huntsman D, Murphy KP, Aparicio S, Shah SP. SNVMix: predicting single nucleotide variants from next-generation sequencing of tumors. Bioinformatics (Oxford, England). 26: 730-6. PMID 20130035 DOI: 10.1093/Bioinformatics/Btq040  0.819
2010 Morin RD, Johnson NA, Severson TM, Mungall AJ, An J, Goya R, Paul JE, Boyle M, Woolcock BW, Kuchenbauer F, Yap D, Humphries RK, Griffith OL, Shah S, Zhu H, ... ... Marra MA, et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nature Genetics. 42: 181-5. PMID 20081860 DOI: 10.1038/ng.518  0.824
2010 Vrljicak P, Chang AC, Morozova O, Wederell ED, Niessen K, Marra MA, Karsan A, Hoodless PA. Genomic analysis distinguishes phases of early development of the mouse atrio-ventricular canal. Physiological Genomics. 40: 150-7. PMID 19952280 DOI: 10.1152/Physiolgenomics.00142.2009  0.699
2010 Starczynowski DT, Kuchenbauer F, Argiropoulos B, Sung S, Morin R, Muranyi A, Hirst M, Hogge D, Marra M, Wells RA, Buckstein R, Lam W, Humphries RK, Karsan A. Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype. Nature Medicine. 16: 49-58. PMID 19898489 DOI: 10.1038/Nm.2054  0.525
2010 Jones SJ, Laskin J, Li YY, Griffith OL, An J, Bilenky M, Butterfield YS, Chuah E, Corbett R, Fejes A, Chan S, Liao N, Kasaian K, Griffith M, Yee J, ... ... Marra MA, et al. Personalized oncogenomics Genome Biology. 11: I5. DOI: 10.1186/gb-2010-11-s1-i5  0.654
2010 Jones SJ, Laskin J, Li YY, Griffith OL, An J, Bilenky M, Butterfield YS, Cezard T, Chuah E, Corbett R, Fejes A, Griffith M, Yee J, Martin M, Mayo M, ... ... Marra MA, et al. Genomic analysis of a rare human tumor Bmc Bioinformatics. 11. DOI: 10.1186/1471-2105-11-S4-O3  0.743
2010 Morin RD, Mendez-Lago M, Mungall AJ, Johnson NA, Goya R, Severson T, Mungall K, An J, Yakovenko O, Jackman S, Krzywinski M, Griffith M, Chan S, Tam A, Smailus D, ... ... Marra MA, et al. Identification of Genes Frequently Mutated In FL and DLBCL with Transcriptome, Genome and Exome Sequencing Blood. 116: 804-804. DOI: 10.1182/Blood.V116.21.804.804  0.843
2010 Mungall AJ, Morin RD, An J, Yakovenko O, Boyle M, Johnson NA, Woolcock B, Leach S, Mayo M, Mendez-Lago M, Munro S, Zeng T, Zhao Y, Hirst M, Holt RA, ... ... Marra MA, et al. Recurrent DNA Mutations In Non-Hodgkin Lymphomas Reveal Candidate Therapeutic Targets Blood. 116: 632-632. DOI: 10.1182/Blood.V116.21.632.632  0.683
2010 Mendez-Lago M, Morin RD, Mungall AJ, Chan S, Chittaranjan S, Severson T, Goya R, Mungall K, Johnson NA, Boyle M, Woolcock B, Zeng T, McDonald H, An J, Yakovenko O, ... ... Marra MA, et al. Mutations In MLL2 and MEF2B Genes In Follicular Lymphoma and Diffuse Large B-Cell Lymphoma Blood. 116: 473-473. DOI: 10.1182/Blood.V116.21.473.473  0.844
2010 Schuetz JM, Johnson NA, Morin RD, Hirst M, Zhao Y, Tam A, Moore R, Zeng T, Marra MA, Connors JM, Brooks-Wilson AR, Gascoyne RD. BCL2 Is Highly Mutated In Diffuse Large B-Cell Lymphoma Blood. 116: 4187-4187. DOI: 10.1182/Blood.V116.21.4187.4187  0.666
2010 Hansford LM, Morozova O, Lipman T, Blakely K, Ohira M, Marrano P, Angelini P, Moffat J, Thiele CJ, Thorner P, Dick J, Nakagawara A, Irwin M, Marra M, Kaplan DR. Abstract 12: Metastatic neuroblastoma cancer stem cells display a mixed phenotype of tumor and niche origin required for survival Cancer Research. 70: 12-12. DOI: 10.1158/1538-7445.Am10-12  0.696
2009 Laskin JJ, Pugh T, Jackson C, Sutcliffe M, Ionescu D, Melosky B, Ho C, Sun S, Murray N, Marra M. Transcriptome-wide mutation discovery in patients in a phase II clinical trial of first-line erlotinib for clinically selected patients with advanced non-small cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 8102. PMID 27964273 DOI: 10.1200/Jco.2009.27.15_Suppl.8102  0.543
2009 Biernaskie J, Paris M, Morozova O, Fagan BM, Marra M, Pevny L, Miller FD. SKPs derive from hair follicle precursors and exhibit properties of adult dermal stem cells. Cell Stem Cell. 5: 610-23. PMID 19951689 DOI: 10.1016/J.Stem.2009.10.019  0.666
2009 Friedman J, Adam S, Arbour L, Armstrong L, Baross A, Birch P, Boerkoel C, Chan S, Chai D, Delaney AD, Flibotte S, Gibson WT, Langlois S, Lemyre E, Li HI, ... ... Marra MA, et al. Detection of pathogenic copy number variants in children with idiopathic intellectual disability using 500 K SNP array genomic hybridization. Bmc Genomics. 10: 526. PMID 19917086 DOI: 10.1186/1471-2164-10-526  0.333
2009 Shah SP, Morin RD, Khattra J, Prentice L, Pugh T, Burleigh A, Delaney A, Gelmon K, Guliany R, Senz J, Steidl C, Holt RA, Jones S, Sun M, Leung G, ... ... Marra MA, et al. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature. 461: 809-13. PMID 19812674 DOI: 10.1038/Nature08489  0.727
2009 Lehman AM, Friedman JM, Chai D, Zahir FR, Marra MA, Prisman L, Tsang E, Eydoux P, Armstrong L. A characteristic syndrome associated with microduplication of 8q12, inclusive of CHD7. European Journal of Medical Genetics. 52: 436-9. PMID 19772954 DOI: 10.1016/J.Ejmg.2009.09.006  0.322
2009 Temple G, Gerhard DS, Rasooly R, Feingold EA, Good PJ, Robinson C, Mandich A, Derge JG, Lewis J, Shoaf D, Collins FS, Jang W, Wagner L, Shenmen CM, ... ... Marra MA, et al. The completion of the Mammalian Gene Collection (MGC). Genome Research. 19: 2324-33. PMID 19767417 DOI: 10.1101/Gr.095976.109  0.707
2009 Diguistini S, Liao NY, Platt D, Robertson G, Seidel M, Chan SK, Docking TR, Birol I, Holt RA, Hirst M, Mardis E, Marra MA, Hamelin RC, Bohlmann J, Breuil C, et al. De novo genome sequence assembly of a filamentous fungus using Sanger, 454 and Illumina sequence data. Genome Biology. 10: R94. PMID 19747388 DOI: 10.1186/Gb-2009-10-9-R94  0.376
2009 Morozova O, Hirst M, Marra MA. Applications of new sequencing technologies for transcriptome analysis. Annual Review of Genomics and Human Genetics. 10: 135-51. PMID 19715439 DOI: 10.1146/Annurev-Genom-082908-145957  0.712
2009 Halaschek-Wiener J, Amirabbasi-Beik M, Monfared N, Pieczyk M, Sailer C, Kollar A, Thomas R, Agalaridis G, Yamada S, Oliveira L, Collins JA, Meneilly G, Marra MA, Madden KM, Le ND, et al. Genetic variation in healthy oldest-old. Plos One. 4: e6641. PMID 19680556 DOI: 10.1371/Journal.Pone.0006641  0.354
2009 Tucker T, Marra M, Friedman JM. Massively parallel sequencing: the next big thing in genetic medicine. American Journal of Human Genetics. 85: 142-54. PMID 19679224 DOI: 10.1016/J.Ajhg.2009.06.022  0.414
2009 Pugh TJ, Keyes M, Barclay L, Delaney A, Krzywinski M, Thomas D, Novik K, Yang C, Agranovich A, McKenzie M, Morris WJ, Olive PL, Marra MA, Moore RA. Sequence variant discovery in DNA repair genes from radiosensitive and radiotolerant prostate brachytherapy patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5008-16. PMID 19638463 DOI: 10.1158/1078-0432.Ccr-08-3357  0.589
2009 Meissner B, Warner A, Wong K, Dube N, Lorch A, McKay SJ, Khattra J, Rogalski T, Somasiri A, Chaudhry I, Fox RM, Miller DM, Baillie DL, Holt RA, Jones SJ, ... Marra MA, et al. An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans. Plos Genetics. 5: e1000537. PMID 19557190 DOI: 10.1371/Journal.Pgen.1000537  0.596
2009 Krzywinski M, Schein J, Birol I, Connors J, Gascoyne R, Horsman D, Jones SJ, Marra MA. Circos: An information aesthetic for comparative genomics Genome Research. 19: 1639-1645. PMID 19541911 DOI: 10.1101/Gr.092759.109  0.365
2009 Morrissy AS, Morin RD, Delaney A, Zeng T, McDonald H, Jones S, Zhao Y, Hirst M, Marra MA. Next-generation tag sequencing for cancer gene expression profiling. Genome Research. 19: 1825-35. PMID 19541910 DOI: 10.1101/Gr.094482.109  0.617
2009 Birol I, Jackman SD, Nielsen CB, Qian JQ, Varhol R, Stazyk G, Morin RD, Zhao Y, Hirst M, Schein JE, Horsman DE, Connors JM, Gascoyne RD, Marra MA, Jones SJM. De novo transcriptome assembly with ABySS Bioinformatics. 25: 2872-2877. PMID 19528083 DOI: 10.1093/Bioinformatics/Btp367  0.615
2009 Shah SP, Köbel M, Senz J, Morin RD, Clarke BA, Wiegand KC, Leung G, Zayed A, Mehl E, Kalloger SE, Sun M, Giuliany R, Yorida E, Jones S, Varhol R, ... ... Marra M, et al. Mutation of FOXL2 in granulosa-cell tumors of the ovary. The New England Journal of Medicine. 360: 2719-29. PMID 19516027 DOI: 10.1056/Nejmoa0902542  0.658
2009 Zahir FR, Langlois S, Gall K, Eydoux P, Marra MA, Friedman JM. A novel de novo 1.1 Mb duplication of 17q21.33 associated with cognitive impairment and other anomalies. American Journal of Medical Genetics. Part A. 149: 1257-62. PMID 19449402 DOI: 10.1002/Ajmg.A.32827  0.323
2009 Wang X, Zhao Y, Wong K, Ehlers P, Kohara Y, Jones SJ, Marra MA, Holt RA, Moerman DG, Hansen D. Identification of genes expressed in the hermaphrodite germ line of C. elegans using SAGE. Bmc Genomics. 10: 213. PMID 19426519 DOI: 10.1186/1471-2164-10-213  0.3
2009 Elsik CG, Tellam RL, Worley KC, Gibbs RA, Muzny DM, Weinstock GM, Adelson DL, Eichler EE, Elnitski L, Guigó R, Hamernik DL, Kappes SM, Lewin HA, Lynn DJ, ... ... Marra MA, et al. The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science (New York, N.Y.). 324: 522-8. PMID 19390049 DOI: 10.1126/Science.1169588  0.413
2009 Hillier LW, Reinke V, Green P, Hirst M, Marra MA, Waterston RH. Massively parallel sequencing of the polyadenylated transcriptome of C. elegans Genome Research. 19: 657-666. PMID 19181841 DOI: 10.1101/Gr.088112.108  0.415
2009 McGhee JD, Fukushige T, Krause MW, Minnema SE, Goszczynski B, Gaudet J, Kohara Y, Bossinger O, Zhao Y, Khattra J, Hirst M, Jones SJ, Marra MA, Ruzanov P, Warner A, et al. ELT-2 is the predominant transcription factor controlling differentiation and function of the C. elegans intestine, from embryo to adult. Developmental Biology. 327: 551-65. PMID 19111532 DOI: 10.1016/J.Ydbio.2008.11.034  0.349
2009 Mullighan CG, Morin R, Zhang J, Hirst M, Zhao Y, Yan C, Finney R, Edmonson M, Su X, Buetow KE, Carroll WL, Chen I, Devidas M, Gerhard D, Harvey RC, ... ... Marra M, et al. Next Generation Transcriptomic Resequencing Identifies Novel Genetic Alterations in High-Risk (HR) Childhood Acute Lymphoblastic Leukemia (ALL): A Report From the Children's Oncology Group (COG) HR ALL TARGET Project. Blood. 114: 704-704. DOI: 10.1182/Blood.V114.22.704.704  0.683
2009 Reiman T, Morin R, Goya R, Wong T, Zhao Y, Hirst M, Pilarski LM, Belch A, Marra M. Comparative Whole Transcriptome Shotgun Sequencing (WTSS) of Myeloma at Diagnosis and at Drug-Resistant Relapse. Blood. 114: 603-603. DOI: 10.1182/Blood.V114.22.603.603  0.645
2009 Mungall AJ, Chu A, Chiu R, Corbett R, Field MA, Jackman SD, Mungall KL, Wong K, Boyle M, Carlsen R, Chan SY, Coope RJN, Hirst CA, Hirst M, Johnson N, ... ... Marra MA, et al. Base-Pair Resolution of Somatic and Germline-Derived Genome Rearrangement Breakpoints in Follicular Lymphoma. Blood. 114: 439-439. DOI: 10.1182/Blood.V114.22.439.439  0.473
2009 Johnson NA, Morin R, Severson T, Mungall AJ, Zhao Y, Schein JE, Boyle M, Woolcock B, Moore R, Holt R, Horsman DE, Connors JM, Jones S, Hirst M, Marra MA, et al. FAS Mutations in Follicular Lymphoma Are Rare but Associated with Aggressive Clinical Behavior. Blood. 114: 3967-3967. DOI: 10.1182/Blood.V114.22.3967.3967  0.686
2009 Kuchenbauer F, Mah SM, McPherson A, Heuser M, Argiropolous B, Morin R, Berg T, Lai D, Muranyi AL, Hogge DE, Ruschmann J, Starczynowski DT, Karsan A, O'Connor M, Eaves CJ, ... ... Marra M, et al. Differential Expression of Mirna* Species in Cancer and the Contribution of MiR-223* to the Development of Acute Myeloid Leukemia. Blood. 114: 2960-2960. DOI: 10.1182/Blood.V114.22.2960.2960  0.521
2009 Cheung K, Johnson N, Affleck J, Severson T, Steidl C, Ben-Neriah S, Schein J, Morin R, Moore R, Shah SP, Qian H, Paul J, Telenius A, Lai B, Relander T, ... ... Marra M, et al. TNFRSF14 Is Mutated in a Subset of Follicular Lymphoma and Correlated with Inferior Prognosis. Blood. 114: 1919-1919. DOI: 10.1182/Blood.V114.22.1919.1919  0.653
2009 Morin R, Johnson N, Severson T, Mungall AJ, An J, Paul J, Boyle M, Woolcock B, Kuchenbauer F, Yap D, Humphries RK, Griffith O, Shah SP, Corbett R, Tam A, ... ... Marra MA, et al. Tyrosine 641 of the EZH2 Oncogene Is Frequently Mutated in Follicular and Diffuse Large B-Cell Lymphomas of Germinal Center Origin. Blood. 114: 139-139. DOI: 10.1182/Blood.V114.22.139.139  0.699
2009 Ahn HW, Zhao H, Harris RA, Coarfa C, Milosavljevic A, Morin RD, Marra MA, Rajkovic A. Massive Parallel Sequencing of Small RNAs from Newborn Mouse Ovaries Identifies Novel miRNAs Preferentially Expressed in the Ovaries. Biology of Reproduction. 81: 565-565. DOI: 10.1093/Biolreprod/81.S1.565  0.567
2008 Delaney AD, Qian H, Friedman JM, Marra MA. Use of Affymetrix mapping arrays in the diagnosis of gene copy number variation. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 8.13. PMID 18972373 DOI: 10.1002/0471142905.Hg0813S59  0.318
2008 Ralph SG, Chun HJ, Kolosova N, Cooper D, Oddy C, Ritland CE, Kirkpatrick R, Moore R, Barber S, Holt RA, Jones SJ, Marra MA, Douglas CJ, Ritland K, Bohlmann J. A conifer genomics resource of 200,000 spruce (Picea spp.) ESTs and 6,464 high-quality, sequence-finished full-length cDNAs for Sitka spruce (Picea sitchensis). Bmc Genomics. 9: 484. PMID 18854048 DOI: 10.1186/1471-2164-9-484  0.386
2008 Kuchenbauer F, Morin RD, Argiropoulos B, Petriv OI, Griffith M, Heuser M, Yung E, Piper J, Delaney A, Prabhu AL, Zhao Y, McDonald H, Zeng T, Hirst M, Hansen CL, ... Marra MA, et al. In-depth characterization of the microRNA transcriptome in a leukemia progression model. Genome Research. 18: 1787-97. PMID 18849523 DOI: 10.1101/Gr.077578.108  0.649
2008 Morozova O, Morozov V, Hoffman BG, Helgason CD, Marra MA. A seriation approach for visualization-driven discovery of co-expression patterns in Serial Analysis of Gene Expression (SAGE) data Plos One. 3. PMID 18787709 DOI: 10.1371/Journal.Pone.0003205  0.692
2008 Morozova O, Marra MA. Applications of next-generation sequencing technologies in functional genomics Genomics. 92: 255-264. PMID 18703132 DOI: 10.1016/J.Ygeno.2008.07.001  0.711
2008 D'Souza CA, Chopra V, Varhol R, Xie YY, Bohacec S, Zhao Y, Lee LL, Bilenky M, Portales-Casamar E, He A, Wasserman WW, Goldowitz D, Marra MA, Holt RA, Simpson EM, et al. Identification of a set of genes showing regionally enriched expression in the mouse brain. Bmc Neuroscience. 9: 66. PMID 18625066 DOI: 10.1186/1471-2202-9-66  0.328
2008 Wederell ED, Bilenky M, Cullum R, Thiessen N, Dagpinar M, Delaney A, Varhol R, Zhao Y, Zeng T, Bernier B, Ingham M, Hirst M, Robertson G, Marra MA, Jones S, et al. Global analysis of in vivo Foxa2-binding sites in mouse adult liver using massively parallel sequencing. Nucleic Acids Research. 36: 4549-64. PMID 18611952 DOI: 10.1093/Nar/Gkn382  0.307
2008 Shin H, Hirst M, Bainbridge MN, Magrini V, Mardis E, Moerman DG, Marra MA, Baillie DL, Jones SJ. Transcriptome analysis for Caenorhabditis elegans based on novel expressed sequence tags. Bmc Biology. 6: 30. PMID 18611272 DOI: 10.1186/1741-7007-6-30  0.624
2008 Morin R, Bainbridge M, Fejes A, Hirst M, Krzywinski M, Pugh T, McDonald H, Varhol R, Jones S, Marra M. Profiling the HeLa S3 transcriptome using randomly primed cDNA and massively parallel short-read sequencing. Biotechniques. 45: 81-94. PMID 18611170 DOI: 10.2144/000112900  0.711
2008 Raouf A, Zhao Y, To K, Stingl J, Delaney A, Barbara M, Iscove N, Jones S, McKinney S, Emerman J, Aparicio S, Marra M, Eaves C. Transcriptome analysis of the normal human mammary cell commitment and differentiation process. Cell Stem Cell. 3: 109-18. PMID 18593563 DOI: 10.1016/J.Stem.2008.05.018  0.336
2008 Pugh TJ, Delaney AD, Farnoud N, Flibotte S, Griffith M, Li HI, Qian H, Farinha P, Gascoyne RD, Marra MA. Impact of whole genome amplification on analysis of copy number variants. Nucleic Acids Research. 36: e80. PMID 18559357 DOI: 10.1093/Nar/Gkn378  0.666
2008 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJM, Marra MA, Helgason CD. Identification of transcripts with enriched expression in the developing and adult pancreas Genome Biology. 9. PMID 18554416 DOI: 10.1186/Gb-2008-9-6-R99  0.33
2008 Morozova O, Marra MA. From cytogenetics to next-generation sequencing technologies: Advances in the detection of genome rearrangements in tumors Biochemistry and Cell Biology. 86: 81-91. PMID 18443621 DOI: 10.1139/O08-003  0.706
2008 Mathewson CA, Schein JE, Marra MA. Large-scale BAC clone restriction digest fingerprinting. Current Protocols in Human Genetics. Unit 5.19. PMID 18428413 DOI: 10.1002/0471142905.Hg0519S53  0.349
2008 Morin RD, O'Connor MD, Griffith M, Kuchenbauer F, Delaney A, Prabhu AL, Zhao Y, McDonald H, Zeng T, Hirst M, Eaves CJ, Marra MA. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. Genome Research. 18: 610-21. PMID 18285502 DOI: 10.1101/Gr.7179508  0.693
2008 Griffith M, Tang MJ, Griffith OL, Morin RD, Chan SY, Asano JK, Zeng T, Flibotte S, Ally A, Baross A, Hirst M, Jones SJM, Morin GB, Tai IT, Marra MA. ALEXA: A microarray design platform for alternative expression analysis [3] Nature Methods. 5: 118. PMID 18235430 DOI: 10.1038/Nmeth0208-118  0.648
2008 Ralph SG, Chun HJ, Cooper D, Kirkpatrick R, Kolosova N, Gunter L, Tuskan GA, Douglas CJ, Holt RA, Jones SJ, Marra MA, Bohlmann J. Analysis of 4,664 high-quality sequence-finished poplar full-length cDNA clones and their utility for the discovery of genes responding to insect feeding. Bmc Genomics. 9: 57. PMID 18230180 DOI: 10.1186/1471-2164-9-57  0.321
2008 Zahir FR, Baross A, Delaney AD, Eydoux P, Fernandes ND, Pugh T, Marra MA, Friedman JM. A patient with vertebral, cognitive and behavioural abnormalities and a de novo deletion of NRXN1alpha. Journal of Medical Genetics. 45: 239-43. PMID 18057082 DOI: 10.1136/Jmg.2007.054437  0.479
2008 Starczynowski DT, Kuchenbauer F, Argiropoulos B, Sung S, Morin R, Muranyi AL, Hirst M, Hogge DE, Marra M, Wells RA, Lam W, Humphries RK, Karsan A. Identification of Mir-145 and Mir-146a as Micrornas Involved in the Pathogenesis of 5q- Syndrome Blood. 112: 853-853. DOI: 10.1182/Blood.V112.11.853.853  0.522
2008 Kent DG, Copley MR, Benz C, Dykstra BJ, Ma E, Cheyne J, Zhao Y, Gasparetto M, Delaney A, Smith C, Marra M, Eaves CJ. New Candidate Regulators of Hematopoietic Stem Cells Identified from Transcriptional Comparisons of Highly Purified Populations of Longterm Repopulating Cells with Markedly Different in Vivo Self-Renewal Activities Blood. 112: 2460-2460. DOI: 10.1182/Blood.V112.11.2460.2460  0.352
2008 Griffith M, Tang MJ, Chan S, Asano JK, Ally A, Pugh T, Tai IT, Marra MA. M1982 Identification of Differentially Expressed Alternative mRNA Isoforms Associated with Chemotherapy Resistance in Colon Cancer Cell Lines Gastroenterology. 134: A-444. DOI: 10.1016/S0016-5085(08)62075-2  0.647
2008 Keyes M, Pugh T, Moore R, Pickles T, Marra M, Agranovich A, Barcla L, Delaney A, Morris WJ, Thomas D. Variants in DNA repair genes and their association with late side-effects in prostate brachytherapy patients Brachytherapy. 7: 122-123. DOI: 10.1016/J.Brachy.2008.02.094  0.501
2007 Hu G, Linning R, McCallum B, Banks T, Cloutier S, Butterfield Y, Liu J, Kirkpatrick R, Stott J, Yang G, Smailus D, Jones S, Marra M, Schein J, Bakkeren G. Generation of a wheat leaf rust, Puccinia triticina, EST database from stage-specific cDNA libraries. Molecular Plant Pathology. 8: 451-67. PMID 20507513 DOI: 10.1111/J.1364-3703.2007.00406.X  0.372
2007 Krzywinski M, Bosdet I, Mathewson C, Wye N, Brebner J, Chiu R, Corbett R, Field M, Lee D, Pugh T, Volik S, Siddiqui A, Jones S, Schein J, Collins C, ... Marra M, et al. A BAC clone fingerprinting approach to the detection of human genome rearrangements. Genome Biology. 8: R224. PMID 17953769 DOI: 10.1186/Gb-2007-8-10-R224  0.764
2007 Baross A, Delaney AD, Li HI, Nayar T, Flibotte S, Qian H, Chan SY, Asano J, Ally A, Cao M, Birch P, Brown-John M, Fernandes N, Go A, Kennedy G, ... ... Marra MA, et al. Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data. Bmc Bioinformatics. 8: 368. PMID 17910767 DOI: 10.1186/1471-2105-8-368  0.344
2007 Stratford AL, Habibi G, Astanehe A, Jiang H, Hu K, Park E, Shadeo A, Buys TP, Lam W, Pugh T, Marra M, Nielsen TO, Klinge U, Mertens PR, Aparicio S, et al. Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy. Breast Cancer Research : Bcr. 9: R61. PMID 17875215 DOI: 10.1186/Bcr1767  0.508
2007 Hunt-Newbury R, Viveiros R, Johnsen R, Mah A, Anastas D, Fang L, Halfnight E, Lee D, Lin J, Lorch A, McKay S, Okada HM, Pan J, Schulz AK, Tu D, ... ... Marra MA, et al. High-throughput in vivo analysis of gene expression in Caenorhabditis elegans. Plos Biology. 5: e237. PMID 17850180 DOI: 10.1371/Journal.Pbio.0050237  0.623
2007 Peng FY, Reid KE, Liao N, Schlosser J, Lijavetzky D, Holt R, Martínez Zapater JM, Jones S, Marra M, Bohlmann J, Lund ST. Generation of ESTs in Vitis vinifera wine grape (Cabernet Sauvignon) and table grape (Muscat Hamburg) and discovery of new candidate genes with potential roles in berry development Gene. 402: 40-50. PMID 17761391 DOI: 10.1016/J.Gene.2007.07.016  0.393
2007 Huang P, Pleasance ED, Maydan JS, Hunt-Newbury R, O'Neil NJ, Mah A, Baillie DL, Marra MA, Moerman DG, Jones SJ. Identification and analysis of internal promoters in Caenorhabditis elegans operons. Genome Research. 17: 1478-85. PMID 17712020 DOI: 10.1101/Gr.6824707  0.626
2007 Snelling WM, Chiu R, Schein JE, Hobbs M, Abbey CA, Adelson DL, Aerts J, Bennett GL, Bosdet IE, Boussaha M, Brauning R, Caetano AR, Costa MM, Crawford AM, Dalrymple BP, ... ... Marra MA, et al. A physical map of the bovine genome. Genome Biology. 8: R165. PMID 17697342 DOI: 10.1186/Gb-2007-8-8-R165  0.707
2007 Hou J, Charters AM, Lee SC, Zhao Y, Wu MK, Jones SJ, Marra MA, Hoodless PA. A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE). Bmc Developmental Biology. 7: 92. PMID 17683524 DOI: 10.1186/1471-213X-7-92  0.319
2007 Pugh TJ, Bebb G, Barclay L, Sutcliffe M, Fee J, Salski C, O'Connor R, Ho C, Murray N, Melosky B, English J, Vielkind J, Horsman D, Laskin JJ, Marra MA. Correlations of EGFR mutations and increases in EGFR and HER2 copy number to gefitinib response in a retrospective analysis of lung cancer patients. Bmc Cancer. 7: 128. PMID 17626639 DOI: 10.1186/1471-2407-7-128  0.533
2007 Hirst M, Delaney A, Rogers SA, Schnerch A, Persaud DR, O'Connor MD, Zeng T, Moksa M, Fichter K, Mah D, Go A, Morin RD, Baross A, Zhao Y, Khattra J, ... ... Marra MA, et al. LongSAGE profiling of nine human embryonic stem cell lines. Genome Biology. 8: R113. PMID 17570852 DOI: 10.1186/Gb-2007-8-6-R113  0.563
2007 Margulies EH, Cooper GM, Asimenos G, Thomas DJ, Dewey CN, Siepel A, Birney E, Keefe D, Schwartz AS, Hou M, Taylor J, Nikolaev S, Montoya-Burgos JI, Löytynoja A, Whelan S, ... ... Marra MA, et al. Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. Genome Research. 17: 760-74. PMID 17567995 DOI: 10.1101/Gr.6034307  0.392
2007 Robertson G, Hirst M, Bainbridge M, Bilenky M, Zhao Y, Zeng T, Euskirchen G, Bernier B, Varhol R, Delaney A, Thiessen N, Griffith OL, He A, Marra M, Snyder M, et al. Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing Nature Methods. 4: 651-657. PMID 17558387 DOI: 10.1038/Nmeth1068  0.37
2007 Ruzanov P, Riddle DL, Marra MA, McKay SJ, Jones SM. Genes that may modulate longevity in C. elegans in both dauer larvae and long-lived daf-2 adults. Experimental Gerontology. 42: 825-39. PMID 17543485 DOI: 10.1016/J.Exger.2007.04.002  0.312
2007 Mikkelsen TS, Wakefield MJ, Aken B, Amemiya CT, Chang JL, Duke S, Garber M, Gentles AJ, Goodstadt L, Heger A, Jurka J, Kamal M, Mauceli E, Searle SM, Sharpe T, ... ... Marra MA, et al. Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature. 447: 167-77. PMID 17495919 DOI: 10.1038/Nature05805  0.413
2007 Kelleher CT, Chiu R, Shin H, Bosdet IE, Krzywinski MI, Fjell CD, Wilkin J, Yin T, DiFazio SP, Ali J, Asano JK, Chan S, Cloutier A, Girn N, Leach S, ... ... Marra MA, et al. A physical map of the highly heterozygous Populus genome: integration with the genome sequence and genetic map and analysis of haplotype variation. The Plant Journal : For Cell and Molecular Biology. 50: 1063-78. PMID 17488239 DOI: 10.1111/J.1365-313X.2007.03112.X  0.721
2007 Gibbs RA, Rogers J, Katze MG, Bumgarner R, Weinstock GM, Mardis ER, Remington KA, Strausberg RL, Venter JC, Wilson RK, Batzer MA, Bustamante CD, Eichler EE, Hahn MW, ... ... Marra MA, et al. Evolutionary and biomedical insights from the rhesus macaque genome. Science (New York, N.Y.). 316: 222-34. PMID 17431167 DOI: 10.1126/Science.1139247  0.375
2007 Zhao Y, Raouf A, Kent D, Khattra J, Delaney A, Schnerch A, Asano J, McDonald H, Chan C, Jones S, Marra MA, Eaves CJ. A modified polymerase chain reaction-long serial analysis of gene expression protocol identifies novel transcripts in human CD34+ bone marrow cells. Stem Cells (Dayton, Ohio). 25: 1681-9. PMID 17412892 DOI: 10.1634/Stemcells.2006-0794  0.367
2007 Quayle SN, Hare H, Delaney AD, Hirst M, Hwang D, Schein JE, Jones SJM, Marra MA, Sadar MD. Novel expressed sequences identified in a model of androgen independent prostate cancer Bmc Genomics. 8: 32-32. PMID 17257419 DOI: 10.1186/1471-2164-8-32  0.371
2007 Khattra J, Delaney AD, Zhao Y, Siddiqui A, Asano J, McDonald H, Pandoh P, Dhalla N, Prabhu AL, Ma K, Lee S, Ally A, Tam A, Sa D, Rogers S, ... ... Marra MA, et al. Large-scale production of SAGE libraries from microdissected tissues, flow-sorted cells, and cell lines. Genome Research. 17: 108-16. PMID 17135571 DOI: 10.1101/Gr.5488207  0.381
2007 McGhee JD, Sleumer MC, Bilenky M, Wong K, McKay SJ, Goszczynski B, Tian H, Krich ND, Khattra J, Holt RA, Baillie DL, Kohara Y, Marra MA, Jones SJ, Moerman DG, et al. The ELT-2 GATA-factor and the global regulation of transcription in the C. elegans intestine. Developmental Biology. 302: 627-45. PMID 17113066 DOI: 10.1016/J.Ydbio.2006.10.024  0.605
2007 Kuchenbauer F, Morin R, Staaf J, Borg A, Agiropoulos B, Delaney A, Zeng T, Mcdonald H, Hirst M, Rovira C, Marra M, Humphries RK. Accurate Detection of the microRNA Transcriptome in a Leukemia Progression Model. Blood. 110: 866-866. DOI: 10.1182/Blood.V110.11.866.866  0.53
2007 Zhao Y, Delaney A, Marra MA, Jiang X, Eaves AC, Eaves CJ. Comparative Transcriptome Analysis of Different Subsets of CD34+ Normal and Chronic Myeloid Leukemia Cells Identifies Novel Perturbations in the CML Stem Cell Population. Blood. 110: 35-35. DOI: 10.1182/Blood.V110.11.35.35  0.374
2007 Cheung K, Telenius A, Lai B, Johnson N, Relander T, Steidl C, Baross A, Qian H, Schein J, Marra M, Connors JM, Gascoyne RD, Horsman DE. High Frequency of 1p36.32 Deletion or Loss of Heterozygosity in Follicular Lymphoma (FL). Blood. 110: 183-183. DOI: 10.1182/Blood.V110.11.183.183  0.374
2007 Kent D, Zhao Y, Bowie M, Dykstra B, Cheyne J, Zhao Y, Delaney A, Hirst M, Marra M, Eaves CJ. Differences in the Transcriptomes of Highly Purified Fetal Liver and Adult Bone Marrow Hematopoietic Stem Cells Revealed by Long Serial Analysis of Gene Expression (LongSAGE) Blood. 110: 1277-1277. DOI: 10.1182/Blood.V110.11.1277.1277  0.379
2007 Laskin JJ, Pugh T, Barclay L, Sutcliffe M, Ionescu D, Lam S, Melosky B, Ho C, Murray N, Lee CW, Marra M. P3-108: Correlative genomics in a phase II clinical trial of first-line therapy of erlotinib for clinically selected patients with advanced non-small cell lung cancer Journal of Thoracic Oncology. 2: S725. DOI: 10.1097/01.Jto.0000284084.26665.47  0.528
2007 Pugh TJ, Delaney AD, Flibotte S, Farnoud N, Li I, Farinha P, Gascoyne RD, Marra MA. PD2-2-7: Two wrongs make a right: the use of whole genome amplification for pair-wise genome-wide copy number analysis of limited patient material Journal of Thoracic Oncology. 2: S442-S443. DOI: 10.1097/01.Jto.0000283361.52989.E3  0.534
2007 Hoffman B, Kok D, Witzsche J, Hirst M, Robertson G, Hoodless PA, Jones, Marra M. Genome-wide analysis of Nkx2.2 binding sites using ChIP-tag sequencing (ChIP-TS) Developmental Biology. 306: 354. DOI: 10.1016/J.Ydbio.2007.03.226  0.345
2006 Chen N, Mah A, Blacque OE, Chu J, Phgora K, Bakhoum MW, Newbury CR, Khattra J, Chan S, Go A, Efimenko E, Johnsen R, Phirke P, Swoboda P, Marra M, et al. Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics. Genome Biology. 7: R126. PMID 17187676 DOI: 10.1186/Gb-2006-7-12-R126  0.642
2006 Sodergren E, Weinstock GM, Davidson EH, Cameron RA, Gibbs RA, Angerer RC, Angerer LM, Arnone MI, Burgess DR, Burke RD, Coffman JA, Dean M, Elphick MR, Ettensohn CA, ... ... Marra MA, et al. The genome of the sea urchin Strongylocentrotus purpuratus. Science (New York, N.Y.). 314: 941-52. PMID 17095691 DOI: 10.1126/Science.1133609  0.734
2006 McLeod MP, Warren RL, Hsiao WW, Araki N, Myhre M, Fernandes C, Miyazawa D, Wong W, Lillquist AL, Wang D, Dosanjh M, Hara H, Petrescu A, Morin RD, Yang G, ... ... Marra MA, et al. The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse. Proceedings of the National Academy of Sciences of the United States of America. 103: 15582-7. PMID 17030794 DOI: 10.1073/Pnas.0607048103  0.618
2006 Bainbridge MN, Warren RL, Hirst M, Romanuik T, Zeng T, Go A, Delaney A, Griffith M, Hickenbotham M, Magrini V, Mardis ER, Sadar MD, Siddiqui AS, Marra MA, Jones SJ. Analysis of the prostate cancer cell line LNCaP transcriptome using a sequencing-by-synthesis approach. Bmc Genomics. 7: 246. PMID 17010196 DOI: 10.1186/1471-2164-7-246  0.591
2006 Friedman JM, Baross A, Delaney AD, Ally A, Arbour L, Armstrong L, Asano J, Bailey DK, Barber S, Birch P, Brown-John M, Cao M, Chan S, Charest DL, Farnoud N, ... ... Marra MA, et al. Oligonucleotide microarray analysis of genomic imbalance in children with mental retardation. American Journal of Human Genetics. 79: 500-13. PMID 16909388 DOI: 10.1086/507471  0.542
2006 Ralph SG, Yueh H, Friedmann M, Aeschliman D, Zeznik JA, Nelson CC, Butterfield YS, Kirkpatrick R, Liu J, Jones SJ, Marra MA, Douglas CJ, Ritland K, Bohlmann J. Conifer defence against insects: microarray gene expression profiling of Sitka spruce (Picea sitchensis) induced by mechanical wounding or feeding by spruce budworms (Choristoneura occidentalis) or white pine weevils (Pissodes strobi) reveals large-scale changes of the host transcriptome. Plant, Cell & Environment. 29: 1545-70. PMID 16898017 DOI: 10.1111/J.1365-3040.2006.01532.X  0.359
2006 Siddiqui AS, Delaney AD, Schnerch A, Griffith OL, Jones SJM, Marra MA. Sequence biases in large scale gene expression profiling data Nucleic Acids Research. 34: e83. PMID 16840527 DOI: 10.1093/Nar/Gkl404  0.349
2006 Lonergan KM, Chari R, Deleeuw RJ, Shadeo A, Chi B, Tsao MS, Jones S, Marra M, Ling V, Ng R, Macaulay C, Lam S, Lam WL. Identification of novel lung genes in bronchial epithelium by serial analysis of gene expression. American Journal of Respiratory Cell and Molecular Biology. 35: 651-61. PMID 16809635 DOI: 10.1165/Rcmb.2006-0056Oc  0.348
2006 Bakkeren G, Jiang G, Warren RL, Butterfield Y, Shin H, Chiu R, Linning R, Schein J, Lee N, Hu G, Kupfer DM, Tang Y, Roe BA, Jones S, Marra M, et al. Mating factor linkage and genome evolution in basidiomycetous pathogens of cereals. Fungal Genetics and Biology : Fg & B. 43: 655-66. PMID 16793293 DOI: 10.1016/J.Fgb.2006.04.002  0.362
2006 Wang G, Jones SJ, Marra MA, Sadar MD. Identification of genes targeted by the androgen and PKA signaling pathways in prostate cancer cells. Oncogene. 25: 7311-23. PMID 16751804 DOI: 10.1038/Sj.Onc.1209715  0.329
2006 Warren RL, Varabei D, Platt D, Huang X, Messina D, Yang SP, Kronstad JW, Krzywinski M, Warren WC, Wallis JW, Hillier LW, Chinwalla AT, Schein JE, Siddiqui AS, Marra MA, et al. Physical map-assisted whole-genome shotgun sequence assemblies. Genome Research. 16: 768-75. PMID 16741162 DOI: 10.1101/Gr.5090606  0.35
2006 Morin RD, Chang E, Petrescu A, Liao N, Griffith M, Chow W, Kirkpatrick R, Butterfield YS, Young AC, Stott J, Barber S, Babakaiff R, Dickson MC, Matsuo C, Wong D, ... ... Marra MA, et al. Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling. Genome Research. 16: 796-803. PMID 16672307 DOI: 10.1101/Gr.4871006  0.692
2006 Ralph S, Oddy C, Cooper D, Yueh H, Jancsik S, Kolosova N, Philippe RN, Aeschliman D, White R, Huber D, Ritland CE, Benoit F, Rigby T, Nantel A, Butterfield YS, ... ... Marra MA, et al. Genomics of hybrid poplar (Populus trichocarpax deltoides) interacting with forest tent caterpillars (Malacosoma disstria): normalized and full-length cDNA libraries, expressed sequence tags, and a cDNA microarray for the study of insect-induced defences in poplar. Molecular Ecology. 15: 1275-97. PMID 16626454 DOI: 10.1111/J.1365-294X.2006.02824.X  0.402
2006 Wilson GM, Flibotte S, Missirlis PI, Marra MA, Jones S, Thornton K, Clark AG, Holt RA. Identification by full-coverage array CGH of human DNA copy number increases relative to chimpanzee and gorilla. Genome Research. 16: 173-81. PMID 16365383 DOI: 10.1101/Gr.4456006  0.361
2006 Bebb DG, Pugh T, Sutcliffe M, Barclay L, Fee J, O’Connor R, Vielkind J, Murray N, Laskin JJ, Marra M. Previously documented mutations in the epidermal growth factor receptor (EGFR) gene in a non-small cell lung cancer (NSCLC) population treated with gefitinib are not associated with response Journal of Clinical Oncology. 24: 7163-7163. DOI: 10.1200/Jco.2006.24.18_Suppl.7163  0.58
2005 Siddiqui AS, Khattra J, Delaney AD, Zhao Y, Astell C, Asano J, Babakaiff R, Barber S, Beland J, Bohacec S, Brown-John M, Chand S, Charest D, Charters AM, Cullum R, ... ... Marra MA, et al. A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 18485-90. PMID 16352711 DOI: 10.1073/Pnas.0509455102  0.379
2005 Everts-van der Wind A, Larkin DM, Green CA, Elliott JS, Olmstead CA, Chiu R, Schein JE, Marra MA, Womack JE, Lewin HA. A high-resolution whole-genome cattle-human comparative map reveals details of mammalian chromosome evolution. Proceedings of the National Academy of Sciences of the United States of America. 102: 18526-31. PMID 16339895 DOI: 10.1073/Pnas.0509285102  0.317
2005 Larraya LM, Boyce KJ, So A, Steen BR, Jones S, Marra M, Kronstad JW. Serial analysis of gene expression reveals conserved links between protein kinase A, ribosome biogenesis, and phosphate metabolism in Ustilago maydis. Eukaryotic Cell. 4: 2029-43. PMID 16339721 DOI: 10.1128/Ec.4.12.2029-2043.2005  0.315
2005 Pavy N, Paule C, Parsons L, Crow JA, Morency MJ, Cooke J, Johnson JE, Noumen E, Guillet-Claude C, Butterfield Y, Barber S, Yang G, Liu J, Stott J, Kirkpatrick R, ... ... Marra M, et al. Generation, annotation, analysis and database integration of 16,500 white spruce EST clusters. Bmc Genomics. 6: 144. PMID 16236172 DOI: 10.1186/1471-2164-6-144  0.397
2005 Smailus DE, Marziali A, Dextras P, Marra MA, Holt RA. Simple, robust methods for high-throughput nanoliter-scale DNA sequencing. Genome Research. 15: 1447-50. PMID 16169928 DOI: 10.1101/Gr.4221805  0.333
2005 Ng SH, Artieri CG, Bosdet IE, Chiu R, Danzmann RG, Davidson WS, Ferguson MM, Fjell CD, Hoyheim B, Jones SJ, de Jong PJ, Koop BF, Krzywinski MI, Lubieniecki K, Marra MA, et al. A physical map of the genome of Atlantic salmon, Salmo salar. Genomics. 86: 396-404. PMID 16026963 DOI: 10.1016/J.Ygeno.2005.06.001  0.722
2005 Ivens AC, Peacock CS, Worthey EA, Murphy L, Aggarwal G, Berriman M, Sisk E, Rajandream MA, Adlem E, Aert R, Anupama A, Apostolou Z, Attipoe P, Bason N, Bauser C, ... ... Marra M, et al. The genome of the kinetoplastid parasite, Leishmania major. Science (New York, N.Y.). 309: 436-42. PMID 16020728 DOI: 10.1126/Science.1112680  0.386
2005 Warren RL, Butterfield YS, Morin RD, Siddiqui AS, Marra MA, Jones SJ. Management and visualization of whole genome shotgun assemblies using SAM. Biotechniques. 38: 715-6, 718, 720. PMID 15945370 DOI: 10.2144/05385St01  0.595
2005 Blacque OE, Perens EA, Boroevich KA, Inglis PN, Li C, Warner A, Khattra J, Holt RA, Ou G, Mah AK, McKay SJ, Huang P, Swoboda P, Jones SJ, Marra MA, et al. Functional genomics of the cilium, a sensory organelle. Current Biology : Cb. 15: 935-41. PMID 15916950 DOI: 10.1016/J.Cub.2005.04.059  0.627
2005 Halaschek-Wiener J, Khattra JS, McKay S, Pouzyrev A, Stott JM, Yang GS, Holt RA, Jones SJ, Marra MA, Brooks-Wilson AR, Riddle DL. Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression. Genome Research. 15: 603-15. PMID 15837805 DOI: 10.1101/Gr.3274805  0.349
2005 Hillier LW, Graves TA, Fulton RS, Fulton LA, Pepin KH, Minx P, Wagner-McPherson C, Layman D, Wylie K, Sekhon M, Becker MC, Fewell GA, Delehaunty KD, Miner TL, Nash WE, ... ... Marra MA, et al. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature. 434: 724-31. PMID 15815621 DOI: 10.1038/Nature03466  0.341
2005 Loftus BJ, Fung E, Roncaglia P, Rowley D, Amedeo P, Bruno D, Vamathevan J, Miranda M, Anderson IJ, Fraser JA, Allen JE, Bosdet IE, Brent MR, Chiu R, Doering TL, ... ... Marra MA, et al. The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science (New York, N.Y.). 307: 1321-4. PMID 15653466 DOI: 10.1126/Science.1103773  0.741
2005 Marra MA, Krzywinski M, Chiu R, Field M, Birol I, D’Souza B, Bosdet I, Mathewson C, Lee D, Baross A, Gascoyne RD, Horsman D, Holt R, Schein J, Connors JM. Towards the Human Cancer Genome Project: A Sequence-Ready Physical Map of a Follicular Lymphoma Genome. Blood. 106: 605-605. DOI: 10.1182/Blood.V106.11.605.605  0.74
2005 Bebb G, Pugh T, Ho C, Laskin J, Murray N, van Niekirk D, Sutcliffe M, Fee J, Brooks-Wilson A, Marra M. O-184 Asian ethnicity, somatic epidermal growth factor receptor (EGFR) mutations and response to gefitinib in non-small cell lung cancer patients treated in a North American setting Lung Cancer. 49: S61. DOI: 10.1016/S0169-5002(05)80318-6  0.525
2004 Hirst M, Astell CR, Griffith M, Coughlin SM, Moksa M, Zeng T, Smailus DE, Holt RA, Jones S, Marra MA, Petric M, Krajden M, Lawrence D, Mak A, Chow R, et al. Novel avian influenza H7N3 strain outbreak, British Columbia. Emerging Infectious Diseases. 10: 2192-5. PMID 15663859 DOI: 10.3201/Eid1012.040743  0.505
2004 Warren R, Hsiao WW, Kudo H, Myhre M, Dosanjh M, Petrescu A, Kobayashi H, Shimizu S, Miyauchi K, Masai E, Yang G, Stott JM, Schein JE, Shin H, Khattra J, ... ... Marra MA, et al. Functional characterization of a catabolic plasmid from polychlorinated- biphenyl-degrading Rhodococcus sp. strain RHA1. Journal of Bacteriology. 186: 7783-95. PMID 15516593 DOI: 10.1128/Jb.186.22.7783-7795.2004  0.366
2004 Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, ... ... Marra MA, et al. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Research. 14: 2121-7. PMID 15489334 DOI: 10.1101/Gr.2596504  0.704
2004 Baross A, Butterfield YS, Coughlin SM, Zeng T, Griffith M, Griffith OL, Petrescu AS, Smailus DE, Khattra J, McDonald HL, McKay SJ, Moksa M, Holt RA, Marra MA. Systematic recovery and analysis of full-ORF human cDNA clones. Genome Research. 14: 2083-92. PMID 15489330 DOI: 10.1101/Gr.2473704  0.604
2004 Anglesio MS, Evdokimova V, Melnyk N, Zhang L, Fernandez CV, Grundy PE, Leach S, Marra MA, Brooks-Wilson AR, Penninger J, Sorensen PH. Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidney. Human Molecular Genetics. 13: 2061-74. PMID 15254018 DOI: 10.1093/Hmg/Ddh215  0.351
2004 Krzywinski M, Bosdet I, Smailus D, Chiu R, Mathewson C, Wye N, Barber S, Brown-John M, Chan S, Chand S, Cloutier A, Girn N, Lee D, Masson A, Mayo M, ... ... Marra MA, et al. A set of BAC clones spanning the human genome. Nucleic Acids Research. 32: 3651-60. PMID 15247347 DOI: 10.1093/Nar/Gkh700  0.717
2004 Garnis C, Coe B, Henderson LJ, Ishkanian A, Watson S, Marra M, Minna J, Lam S, MacAulay C, Lam W. Construction and optimization of chromosome arm-specific comparative genomic hybridization arrays for identifying genetic alterations in preinvasive lung cancers. Chest. 125: 104S-5S. PMID 15136441 DOI: 10.1378/Chest.125.5_Suppl.104S  0.318
2004 MacAulay C, Lonergan K, Chi B, Zuyderduyn S, Shein J, Tsao M, LeRiche J, Jones S, Marra M, Lam S, Lam WL. Serial analysis of gene expression profiles of developmental stages in non-small cell lung carcinoma. Chest. 125: 97S. PMID 15136435 DOI: 10.1378/Chest.125.5_Suppl.97S  0.302
2004 Krzywinski M, Wallis J, Gösele C, Bosdet I, Chiu R, Graves T, Hummel O, Layman D, Mathewson C, Wye N, Zhu B, Albracht D, Asano J, Barber S, Brown-John M, ... ... Marra M, et al. Integrated and sequence-ordered BAC- and YAC-based physical maps for the rat genome. Genome Research. 14: 766-79. PMID 15060021 DOI: 10.1101/Gr.2336604  0.71
2004 Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, ... ... Marra M, et al. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature. 428: 493-521. PMID 15057822 DOI: 10.1038/Nature02426  0.733
2004 Ishkanian AS, Malloff CA, Watson SK, DeLeeuw RJ, Chi B, Coe BP, Snijders A, Albertson DG, Pinkel D, Marra MA, Ling V, MacAulay C, Lam WL. A tiling resolution DNA microarray with complete coverage of the human genome. Nature Genetics. 36: 299-303. PMID 14981516 DOI: 10.1038/Ng1307  0.421
2004 Baross A, Schertzer M, Zuyderduyn SD, Jones SJ, Marra MA, Lansdorp PM. Effect of TERT and ATM on gene expression profiles in human fibroblasts. Genes, Chromosomes & Cancer. 39: 298-310. PMID 14978791 DOI: 10.1002/Gcc.20006  0.411
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