| Year |
Citation |
Score |
| 2023 |
Sack KD, Eaton N, Tehrani MD, Flaumenhaft R. Interferons prime the endothelium for toll-like receptor-mediated thrombin generation. Journal of Thrombosis and Haemostasis : Jth. PMID 38159649 DOI: 10.1016/j.jtha.2023.12.021 |
0.768 |
|
| 2023 |
Lin L, Chen DY, Scartelli C, Xie H, Merrill-Skoloff G, Yang M, Sun L, Saeed M, Flaumenhaft R. Plant flavonoid inhibition of SARS-CoV-2 main protease and viral replication. Iscience. 26: 107602. PMID 37664626 DOI: 10.1016/j.isci.2023.107602 |
0.75 |
|
| 2023 |
Muse O, Patell R, Peters CG, Yang M, El-Darzi E, Schulman S, Falanga A, Marchetti M, Russo L, Zwicker JI, Flaumenhaft R. The unfolded protein response links ER stress to cancer-associated thrombosis. Jci Insight. PMID 37651191 DOI: 10.1172/jci.insight.170148 |
0.779 |
|
| 2023 |
Fritz DI, Ding Y, Merrill-Skoloff G, Flaumenhaft R, Hanada T, Chishti AH. Dematin Regulates Calcium Mobilization, Thrombosis, and Early Akt Activation in Platelets. Molecular and Cellular Biology. 1-17. PMID 37216480 DOI: 10.1080/10985549.2023.2210033 |
0.361 |
|
| 2023 |
Roka-Moiia Y, Ammann KR, Miller-Gutierrez S, Sheriff J, Bluestein D, Italiano JE, Flaumenhaft RC, Slepian MJ. Shear-Mediated Platelet Microparticles Demonstrate Phenotypic Heterogeneity as to Morphology, Receptor Distribution, and Hemostatic Function. International Journal of Molecular Sciences. 24. PMID 37108551 DOI: 10.3390/ijms24087386 |
0.324 |
|
| 2023 |
Liao X, Ji P, Chi K, Chen X, Zhou Y, Chen S, Cheng Y, Flaumenhaft R, Yuan C, Huang M. Enhanced inhibition of protein disulfide isomerase and anti-thrombotic activity of a rutin derivative: rutin:Zn complex. Rsc Advances. 13: 11464-11471. PMID 37063725 DOI: 10.1039/d3ra01135f |
0.448 |
|
| 2023 |
Yang M, Chiu J, Scartelli C, Ponzar N, Patel S, Patel A, Ferreira RB, Keyes RF, Carroll K, Pozzi N, Hogg PJ, Smith BC, Flaumenhaft R. Sulfenylation links oxidative stress to protein disulfide isomerase oxidase activity and thrombus formation. Journal of Thrombosis and Haemostasis : Jth. PMID 37037379 DOI: 10.1016/j.jtha.2023.03.034 |
0.762 |
|
| 2023 |
Schmaier AA, Anderson PF, Chen SM, El-Darzi E, Aivasovsky I, Kaushik MP, Sack KD, Hartzell HC, Parikh SM, Flaumenhaft R, Schulman S. TMEM16E regulates endothelial cell procoagulant activity and thrombosis. The Journal of Clinical Investigation. PMID 36951953 DOI: 10.1172/JCI163808 |
0.812 |
|
| 2022 |
Shieh M, Ni X, Xu S, Lindahl SP, Yang M, Matsunaga T, Flaumenhaft R, Akaike T, Xian M. Shining a light on SSP4: A comprehensive analysis and biological applications for the detection of sulfane sulfurs. Redox Biology. 56: 102433. PMID 35987086 DOI: 10.1016/j.redox.2022.102433 |
0.707 |
|
| 2022 |
Liao X, Zhuang X, Liang C, Li J, Flaumenhaft R, Yuan C, Huang M. Flavonoids as Protein Disulfide Isomerase Inhibitors: Key Molecular and Structural Features for the Interaction. Journal of Agricultural and Food Chemistry. 70: 4475-4483. PMID 35377153 DOI: 10.1021/acs.jafc.1c07994 |
0.509 |
|
| 2022 |
Zhu W, Guo S, Homilius M, Nsubuga C, Wright SH, Quan D, Kc A, Eddy SS, Victorio RA, Beerens M, Flaumenhaft R, Deo RC, MacRae CA. PIEZO1 mediates a mechanothrombotic pathway in diabetes. Science Translational Medicine. 14: eabk1707. PMID 34985971 DOI: 10.1126/scitranslmed.abk1707 |
0.63 |
|
| 2021 |
Liang C, Flaumenhaft R, Yuan C, Huang M. Vascular thiol isomerases: structures, regulatory mechanisms, and inhibitor development. Drug Discovery Today. PMID 34757205 DOI: 10.1016/j.drudis.2021.10.018 |
0.497 |
|
| 2021 |
Schmaier AA, Pajares Hurtado GM, Manickas-Hill ZJ, Sack KD, Chen SM, Bhambhani V, Quadir J, Nath AK, Collier AY, Ngo D, Barouch DH, Shapiro NI, Gerszten RE, Yu X, Peters KG, ... Flaumenhaft R, et al. Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19. Jci Insight. PMID 34506304 DOI: 10.1172/jci.insight.151527 |
0.792 |
|
| 2021 |
Revollo LD, Merrill-Skoloff G, De Ceunynck K, Dilks JR, Guo S, Bordoli MR, Peters CG, Noetzli L, Ionescu AM, Rosen V, Italiano JE, Whitman M, Flaumenhaft R. The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation. Blood. PMID 34329392 DOI: 10.1182/blood.2020010342 |
0.745 |
|
| 2021 |
Yang M, Flaumenhaft R. Oxidative Cysteine Modification of Thiol Isomerases in Thrombotic Disease: A Hypothesis. Antioxidants & Redox Signaling. PMID 34121445 DOI: 10.1089/ars.2021.0108 |
0.724 |
|
| 2021 |
Schmaier AA, Hurtado GP, Manickas-Hill ZJ, Sack KD, Chen SM, Bhambhani V, Quadir J, Nath AK, Collier AY, Ngo D, Barouch DH, Gerszten RE, Yu XG, Peters K, ... Flaumenhaft R, et al. Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 34031665 DOI: 10.1101/2021.05.13.21257070 |
0.796 |
|
| 2020 |
Grover SP, Bendapudi PK, Yang M, Merrill-Skoloff G, Govindarajan V, Mitrophanov AY, Flaumenhaft R. Injury measurements improve interpretation of thrombus formation data in the cremaster arteriole laser-induced injury model of thrombosis. Journal of Thrombosis and Haemostasis : Jth. 18: 3078-3085. PMID 33456401 DOI: 10.1111/jth.15059 |
0.736 |
|
| 2020 |
Yang M, Li W, Harberg C, Chen W, Yue H, Ferreira RB, Wynia-Smith SL, Carroll KS, Zielonka J, Flaumenhaft R, Silverstein RL, Smith BC. Cysteine sulfenylation by CD36 signaling promotes arterial thrombosis in dyslipidemia. Blood Advances. 4: 4494-4507. PMID 32946569 DOI: 10.1182/Bloodadvances.2020001609 |
0.798 |
|
| 2020 |
Chinnaraj M, Barrios DA, Frieden C, Heyduk T, Flaumenhaft R, Pozzi N. Bioorthogonal Chemistry Enables Single-Molecule FRET Measurements of Catalytically Active Protein Disulfide Isomerase. Chembiochem : a European Journal of Chemical Biology. PMID 32857455 DOI: 10.1002/Cbic.202000537 |
0.767 |
|
| 2020 |
Matsuura S, Thompson CR, Belghasem ME, Bekendam RH, Piasecki A, Leiva O, Ray A, Italiano J, Yang M, Merill-Skoloff G, Chitalia VC, Flaumenhaft R, Ravid K. Platelet Dysfunction and Thrombosis in JAK2-Mutated Primary Myelofibrotic Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314760. PMID 32814440 DOI: 10.1161/Atvbaha.120.314760 |
0.776 |
|
| 2020 |
Greve E, Lindeman SV, Scartelli C, Lin L, Flaumenhaft R, Dockendorff C. Route exploration and synthesis of the reported pyridone-based PDI inhibitor STK076545. Organic & Biomolecular Chemistry. PMID 32812971 DOI: 10.1039/D0Ob01205J |
0.507 |
|
| 2020 |
Gao Y, Sarode A, Kokoroskos N, Ukidve A, Zhao Z, Guo S, Flaumenhaft R, Gupta AS, Saillant N, Mitragotri S. A polymer-based systemic hemostatic agent. Science Advances. 6: eaba0588. PMID 32775633 DOI: 10.1126/Sciadv.Aba0588 |
0.708 |
|
| 2020 |
Schulman S, El-Darzi E, Florido MH, Friesen M, Merrill-Skoloff G, Brake MA, Schuster CR, Lin L, Westrick RJ, Cowan CA, Flaumenhaft R, BioResource N, Ouwehand WH, Peerlinck K, Freson K, et al. A coagulation defect arising from heterozygous premature termination of tissue factor. The Journal of Clinical Investigation. PMID 32663190 DOI: 10.1172/Jci133780 |
0.75 |
|
| 2020 |
Mitrophanov AY, Merrill-Skoloff G, Grover SP, Govindarajan V, Kolanjiyil A, Hariprasad DS, Unnikrishnan G, Flaumenhaft R, Reifman J. Injury Length and Arteriole Constriction Shape Clot Growth and Blood-Flow Acceleration in a Mouse Model of Thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314786. PMID 32640902 DOI: 10.1161/Atvbaha.120.314786 |
0.318 |
|
| 2020 |
Sharda AV, Barr AM, Harrison JA, Wilkie AR, Fang C, Mendez LM, Ghiran IC, Italiano JE, Flaumenhaft R. vWF maturation and release are controlled by two regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2. Blood. PMID 32614949 DOI: 10.1182/Blood.2020005300 |
0.377 |
|
| 2020 |
Chaudhry SA, Serrata M, Tomczak L, Higgins S, Ryu J, Laprise D, Enjyoji K, Bekendam R, Kaushik V, Flaumenhaft R, Bendapudi PK. Cationic Zinc is Required for Factor XII Recruitment and Activation by Stimulated Platelets and for Thrombus Formation in vivo. Journal of Thrombosis and Haemostasis : Jth. PMID 32542960 DOI: 10.1111/Jth.14964 |
0.762 |
|
| 2020 |
Revollo L, Merrill-Skoloff G, De Ceunynck K, Dilks J, Bordoli M, Peters C, Noetzli L, Ionescu A, Rosen V, Italiano JE, Whitman M, Flaumenhaft R. The Secreted Tyrosine Kinase Vlk Is Essential for Normal Platelet Activation and Thrombus Formation Blood. 136: 10-11. DOI: 10.1182/blood-2020-137243 |
0.372 |
|
| 2019 |
Battinelli EM, Thon JN, Okazaki R, Peters CG, Vijey P, Wilkie AR, Noetzli LJ, Flaumenhaft R, Italiano JE. Megakaryocytes package contents into separate α-granules that are differentially distributed in platelets. Blood Advances. 3: 3092-3098. PMID 31648331 DOI: 10.1182/Bloodadvances.2018020834 |
0.425 |
|
| 2019 |
Bekendam RH, Flaumenhaft R. Assays of Thiol Isomerase Enzymatic Activity. Methods in Molecular Biology (Clifton, N.J.). 1967: 133-148. PMID 31069768 DOI: 10.1007/978-1-4939-9187-7_8 |
0.328 |
|
| 2019 |
Eriksson O, Chiu J, Hogg PJ, Atkinson JP, Liszewski MK, Flaumenhaft R, Furie B. Thiol isomerase ERp57 targets and modulates the lectin pathway of complement activation. The Journal of Biological Chemistry. PMID 30670593 DOI: 10.1074/Jbc.Ra118.006792 |
0.79 |
|
| 2019 |
Zwicker JI, Schlechter BL, Stopa JD, Liebman H, Aggarwal A, Puligandla M, Caughey T, Bauer KA, Kuemmerle N, Wong E, Wun T, McLaughlin M, Hidalgo M, Neuberg D, Furie B, ... Flaumenhaft R, et al. Targeting protein disulfide isomerase with the flavonoid isoquercetin to improve hypercoagulability in advanced cancer. Jci Insight. PMID 30652973 DOI: 10.1172/Jci.Insight.125851 |
0.822 |
|
| 2019 |
Roweth HG, Malloy M, Forward JA, Ceglowski J, Flaumenhaft RC, Italiano JE, Battinelli E. The Effects of Antiplatelet Agents on Endocytosis Blood. 134: 1058-1058. DOI: 10.1182/blood-2019-131912 |
0.404 |
|
| 2019 |
Muse O, Patell R, Peters C, Schulman S, Darzi E, Schuster C, Huang L, Mukherjee S, Muthuswamy S, Zwicker JI, Flaumenhaft RC. The Unfolded Protein Response Causes Prothrombotic Transformation of Pancreatic Cancer Linking Tumor Progression with Cancer-Associated Thrombosis Blood. 134: 632-632. DOI: 10.1182/Blood-2019-123544 |
0.595 |
|
| 2019 |
Chaudhry SA, Serrata M, Enjoji K, Flaumenhaft R, Bendapudi PK. PC240. Surface Activation of Factor XII by Activated Platelets Contributes to Arterial Thrombus Formation Journal of Vascular Surgery. 69. DOI: 10.1016/J.Jvs.2019.04.413 |
0.404 |
|
| 2018 |
Wang X, Xue G, Song M, Xu P, Chen D, Yuan C, Lin L, Flaumenhaft R, Li J, Huang M. Molecular basis of rutin inhibition of protein disulfide isomerase (PDI) by combined and experimental methods. Rsc Advances. 8: 18480-18491. PMID 35541126 DOI: 10.1039/c8ra02683a |
0.609 |
|
| 2018 |
Bekendam RH, Iyu D, Passam F, Stopa JD, De Ceunynck K, Muse O, Bendapudi PK, Garnier CL, Gopal S, Crescence L, Chiu J, Furie B, Panicot-Dubois L, Hogg PJ, Dubois C, ... Flaumenhaft R, et al. Protein disulfide isomerase regulation by nitric oxide maintains vascular quiescence and controls thrombus formation. Journal of Thrombosis and Haemostasis : Jth. PMID 30207066 DOI: 10.1111/Jth.14291 |
0.809 |
|
| 2018 |
Sharda A, Flaumenhaft R. The life cycle of platelet granules. F1000research. 7: 236. PMID 29560259 DOI: 10.12688/F1000Research.13283.1 |
0.433 |
|
| 2018 |
Higgins SJ, Ceunynck K, Kellum J, Chen X, Gu X, Chaudhry SA, Schulman S, Libermann TA, Lu S, Shapiro NI, Christiani DC, Flaumenhaft R, Parikh SM. Tie2 protects the vasculature against thrombus formation in systemic inflammation. The Journal of Clinical Investigation. PMID 29360642 DOI: 10.1172/Jci97488 |
0.796 |
|
| 2018 |
De Ceunynck K, Peters CG, Jain A, Higgins SJ, Aisiku O, Fitch-Tewfik JL, Chaudhry SA, Dockendorff C, Parikh SM, Ingber DE, Flaumenhaft R. PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 29343648 DOI: 10.1073/Pnas.1718600115 |
0.747 |
|
| 2018 |
Zwicker JI, Schlechter BL, Stopa JD, Liebman HA, Aggarwal A, Caughey T, Bauer KA, Kuemmerle N, Wong EY, Wun T, Mclaughlin M, Puligandla M, Neuberg DS, Furie B, Flaumenhaft RC. Targeting Protein Disulfide Isomerase with the Oral Flavonoid Isoquercetin Prevents Venous Thromboembolism in Advanced Cancer: Results of a Multi-Dose, Multi-Center, Phase II Clinical Trial (CATIQ Study) Blood. 132: 985-985. DOI: 10.1182/Blood-2018-99-114946 |
0.785 |
|
| 2018 |
Wang X, Xue G, Song M, Xu P, Chen D, Yuan C, Lin L, Flaumenhaft R, Li J, Huang M. Molecular basis of rutin inhibition of protein disulfide isomerase (PDI) by combined in silico and experimental methods Rsc Advances. 8: 18480-18491. DOI: 10.1039/C8Ra02683A |
0.334 |
|
| 2017 |
Flaumenhaft R, De Ceunynck K. Targeting PAR1: Now What? Trends in Pharmacological Sciences. 38: 701-716. PMID 28558960 DOI: 10.1016/J.Tips.2017.05.001 |
0.307 |
|
| 2017 |
Jain A, Barrile R, van der Meer AD, Mammoto A, Mammoto T, De Ceunynck K, Aisiku O, Otieno MA, Louden CS, Hamilton GA, Flaumenhaft R, Ingber DE. A primary human lung alveolus-on-a-chip model of intravascular thrombosis for assessment of therapeutics. Clinical Pharmacology and Therapeutics. PMID 28516446 DOI: 10.1002/Cpt.742 |
0.379 |
|
| 2017 |
Stopa JD, Baker KM, Grover SP, Flaumenhaft R, Furie B. Kinetic-based Trapping by Intervening Sequence Variants of the Active Sites of Protein Disulfide Isomerase Identifies Platelet Protein Substrates. The Journal of Biological Chemistry. PMID 28364042 DOI: 10.1074/Jbc.M116.771832 |
0.793 |
|
| 2017 |
Flaumenhaft R. Stressed platelets ASK1 for a MAPK. Blood. 129: 1066-1068. PMID 28254824 DOI: 10.1182/Blood-2017-01-760546 |
0.426 |
|
| 2017 |
Stopa JD, Neuberg D, Puligandla M, Furie B, Flaumenhaft R, Zwicker JI. Protein disulfide isomerase inhibition blocks thrombin generation in humans by interfering with platelet factor V activation. Jci Insight. 2: e89373. PMID 28097231 DOI: 10.1172/Jci.Insight.89373 |
0.823 |
|
| 2016 |
Schiemer J, Bohm A, Lin L, Merrill-Skoloff G, Flaumenhaft R, Huang JS, Le Breton GC, Chishti AH. Galpha13 Switch Region 2 Relieves Talin Autoinhibition to activate alphaIIbbeta3 Integrin. The Journal of Biological Chemistry. PMID 27803165 DOI: 10.1074/Jbc.M116.747279 |
0.368 |
|
| 2016 |
Flaumenhaft R. Young platelets out-of-control. Thrombosis and Haemostasis. 116: 780. PMID 27683761 DOI: 10.1160/Th16-09-0701 |
0.381 |
|
| 2016 |
Bekendam RH, Bendapudi PK, Lin L, Nag PP, Pu J, Kennedy DR, Feldenzer A, Chiu J, Cook KM, Furie B, Huang M, Hogg PJ, Flaumenhaft R. A substrate-driven allosteric switch that enhances PDI catalytic activity. Nature Communications. 7: 12579. PMID 27573496 DOI: 10.1038/Ncomms12579 |
0.7 |
|
| 2016 |
Flaumenhaft R. SERCAmnavigating calcium signaling in platelets. Blood. 128: 1034-5. PMID 27563149 DOI: 10.1182/Blood-2016-07-723965 |
0.354 |
|
| 2016 |
Flaumenhaft R, Furie B. Vascular thiol isomerases. Blood. 128: 893-901. PMID 27357699 DOI: 10.1182/Blood-2016-04-636456 |
0.635 |
|
| 2016 |
Atefi G, Aisiku O, Shapiro N, Hauser C, Dalle Lucca J, Flaumenhaft R, Tsokos GC. Complement Activation in Trauma Patients Alters Platelet Function. Shock (Augusta, Ga.). 46: 83-8. PMID 27355402 DOI: 10.1097/Shk.0000000000000675 |
0.44 |
|
| 2016 |
Gong L, Proulle V, Fang C, Hong Z, Lin Z, Liu M, Xue G, Yuan C, Lin L, Furie B, Flaumenhaft R, Andreasen P, Furie B, Huang M. A specific plasminogen activator inhibitor-1 antagonist derived from inactivated urokinase. Journal of Cellular and Molecular Medicine. PMID 27197780 DOI: 10.1111/Jcmm.12875 |
0.741 |
|
| 2016 |
Bekendam RH, Flaumenhaft R. Inhibition of Protein Disulfide Isomerase in Thrombosis. Basic & Clinical Pharmacology & Toxicology. 119: 42-48. PMID 26919268 DOI: 10.1111/Bcpt.12573 |
0.484 |
|
| 2016 |
Jain A, Graveline A, Waterhouse A, Vernet A, Flaumenhaft R, Ingber DE. A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function. Nature Communications. 7: 10176. PMID 26733371 DOI: 10.1038/Ncomms10176 |
0.351 |
|
| 2016 |
Schiemer J, Bohm A, Merrill-Skoloff G, Flaumenhaft RC, Le Breton G, Chishti A. Gα13 Switch Region 2 Relieves Talin Autoinhibition to Activate Platelet αIIbβ3 Integrin Blood. 128: 712-712. DOI: 10.1182/Blood.V128.22.712.712 |
0.305 |
|
| 2016 |
De Ceunynck KE, Peters CG, Chaudhry SA, Jain A, Higgins SJ, Aisiku O, Fitch-Tewfik J, Dockendorff C, Parikh S, Ingber DE, Flaumenhaft RC. A Chemical APC Mimetic Protects Endothelium from Thromboinflammatory Injury Blood. 128: 3835-3835. DOI: 10.1182/Blood.V128.22.3835.3835 |
0.335 |
|
| 2016 |
De Ceunynck KE, Higgins SJ, Chaudhry SA, Parikh S, Flaumenhaft RC. Dysfunctional Endothelium Drives a Pre-DIC State in Endotoxemia Blood. 128: 3725-3725. DOI: 10.1182/BLOOD.V128.22.3725.3725 |
0.345 |
|
| 2016 |
Stopa JD, Neuberg DS, Puligandla M, Furie B, Flaumenhaft RC, Zwicker JI. PDI Inhibition Blocks Thrombin Generation in Humans By Interfering with Platelet Factor V Activation Blood. 128: 2628-2628. DOI: 10.1182/Blood.V128.22.2628.2628 |
0.828 |
|
| 2016 |
Bendapudi PK, Deceunynck K, Koseoglu S, Bekendam RH, Mason SD, Kenniston J, Flaumenhaft RC. Stimulated Platelets but Not Endothelium Generate Thrombin Via a Factor XIIa-Dependent Mechanism Requiring Phosphatidylserine Exposure Blood. 128: 258-258. DOI: 10.1182/Blood.V128.22.258.258 |
0.414 |
|
| 2015 |
Schulman S, Bendapudi P, Sharda A, Chen V, Bellido-Martin L, Jasuja R, Furie BC, Flaumenhaft R, Furie B. EXTRACELLULAR THIOL ISOMERASES AND THEIR ROLE IN THROMBUS FORMATION. Antioxidants & Redox Signaling. PMID 26467859 DOI: 10.1089/Ars.2015.6530 |
0.689 |
|
| 2015 |
Lin L, Gopal S, Sharda A, Passam F, Bowley SR, Stopa J, Xue G, Yuan C, Furie BC, Flaumenhaft R, Huang M, Furie B. Quercetin-3-rutinoside Inhibits Protein Disulfide Isomerase by Binding to Its b'x Domain. The Journal of Biological Chemistry. 290: 23543-52. PMID 26240139 DOI: 10.1074/Jbc.M115.666180 |
0.773 |
|
| 2015 |
Flaumenhaft R. A new story ARC for α-granule formation. Blood. 126: 123-4. PMID 26160182 DOI: 10.1182/Blood-2015-05-645739 |
0.337 |
|
| 2015 |
Koseoglu S, Peters CG, Fitch-Tewfik JL, Aisiku O, Danglot L, Galli T, Flaumenhaft R. VAMP-7 links granule exocytosis to actin reorganization during platelet activation. Blood. 126: 651-60. PMID 25999457 DOI: 10.1182/Blood-2014-12-618744 |
0.46 |
|
| 2015 |
Sakurai Y, Fitch-Tewfik JL, Qiu Y, Ahn B, Myers DR, Tran R, Fay ME, Ding L, Spearman PW, Michelson AD, Flaumenhaft R, Lam WA. Platelet geometry sensing spatially regulates α-granule secretion to enable matrix self-deposition. Blood. 126: 531-8. PMID 25964667 DOI: 10.1182/Blood-2014-11-607614 |
0.449 |
|
| 2015 |
Sharda A, Kim SH, Jasuja R, Gopal S, Flaumenhaft R, Furie BC, Furie B. Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome. Blood. 125: 1633-42. PMID 25593336 DOI: 10.1182/Blood-2014-08-597419 |
0.647 |
|
| 2015 |
Aisiku O, Peters CG, De Ceunynck K, Ghosh CC, Dilks JR, Fustolo-Gunnink SF, Huang M, Dockendorff C, Parikh SM, Flaumenhaft R. Parmodulins inhibit thrombus formation without inducing endothelial injury caused by vorapaxar. Blood. 125: 1976-85. PMID 25587041 DOI: 10.1182/Blood-2014-09-599910 |
0.57 |
|
| 2015 |
Flaumenhaft R. Making (anti)sense of factor XI in thrombosis. The New England Journal of Medicine. 372: 277-8. PMID 25482334 DOI: 10.1056/Nejme1413874 |
0.373 |
|
| 2015 |
Flaumenhaft R, Furie B, Zwicker JI. Therapeutic implications of protein disulfide isomerase inhibition in thrombotic disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 16-23. PMID 25104801 DOI: 10.1161/Atvbaha.114.303410 |
0.645 |
|
| 2014 |
Furie B, Flaumenhaft R. Thiol isomerases in thrombus formation. Circulation Research. 114: 1162-73. PMID 24677236 DOI: 10.1161/Circresaha.114.301808 |
0.671 |
|
| 2014 |
Flaumenhaft R. Bioengineering in platelet biology. Thrombosis Research. 133: 523-4. PMID 24433610 DOI: 10.1016/J.Thromres.2013.12.036 |
0.423 |
|
| 2014 |
Battinelli EM, Markens BA, Kulenthirarajan RA, Machlus KR, Flaumenhaft R, Italiano JE. Anticoagulation inhibits tumor cell-mediated release of platelet angiogenic proteins and diminishes platelet angiogenic response. Blood. 123: 101-12. PMID 24065244 DOI: 10.1182/Blood-2013-02-485011 |
0.486 |
|
| 2014 |
Furie B, Furie BC, Flaumenhaft R, Zwicker JI. Animal Models of Arterial and Venous Thrombosis Blood. 124. DOI: 10.1182/Blood.V124.21.Sci-2.Sci-2 |
0.684 |
|
| 2014 |
Bekendam RH, Srila G, Bendapudi PK, Dilks JR, Lin L, Bowley S, Stopa J, Huang M, Furie B, Croce K, Flaumenhaft R. Regulation of Protein Disulfide Isomerase By S-Nitrosylation Controls Its Function during Thrombus Formation Blood. 124: 93-93. DOI: 10.1182/Blood.V124.21.93.93 |
0.828 |
|
| 2014 |
Bendapudi PK, Bekendam RH, Lin L, Huang M, Furie B, Flaumenhaft R. ML359, a Small Molecule Inhibitor of Protein Disulfide Isomerase That Prevents Thrombus Formation and Inhibits Oxidoreductase but Not Transnitrosylase Activity Blood. 124: 2880-2880. DOI: 10.1182/Blood.V124.21.2880.2880 |
0.641 |
|
| 2014 |
Sakurai Y, Fitch-Tewfik JL, Qiu Y, Myers DR, Ahn B, Flaumenhaft R, Lam WA. “Self-Deposition” of Matrix Proteins from Platelet α-Granules Enable Extended Adhesion and Spreading on Micron/Submicron-Scale Fibrinogen and Collagen Substrates. Blood. 124: 2764-2764. DOI: 10.1182/Blood.V124.21.2764.2764 |
0.465 |
|
| 2013 |
Koseoglu S, Flaumenhaft R. Advances in platelet granule biology. Current Opinion in Hematology. 20: 464-71. PMID 23839294 DOI: 10.1097/Moh.0B013E3283632E6B |
0.374 |
|
| 2013 |
Fitch-Tewfik JL, Flaumenhaft R. Platelet granule exocytosis: a comparison with chromaffin cells. Frontiers in Endocrinology. 4: 77. PMID 23805129 DOI: 10.3389/Fendo.2013.00077 |
0.435 |
|
| 2013 |
Flaumenhaft R. Protein disulfide isomerase as an antithrombotic target. Trends in Cardiovascular Medicine. 23: 264-8. PMID 23541171 DOI: 10.1016/J.Tcm.2013.03.001 |
0.468 |
|
| 2013 |
Koseoglu S, Dilks JR, Peters CG, Fitch-Tewfik JL, Fadel NA, Jasuja R, Italiano JE, Haynes CL, Flaumenhaft R. Dynamin-related protein-1 controls fusion pore dynamics during platelet granule exocytosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 481-8. PMID 23288151 DOI: 10.1161/Atvbaha.112.255737 |
0.476 |
|
| 2013 |
Kennedy DR, Nag PP, Galinski CN, Bowley S, Bekendam RH, Dilks JR, Scalise AA, van Hessem L, Pu J, Pilyugina T, Dandapani S, Munoz B, Flaumenhaft R. Development Of Second Generation Thiol Isomerase Inhibitors To Prevent Thrombus Formation Blood. 122: 926-926. DOI: 10.1182/Blood.V122.21.926.926 |
0.761 |
|
| 2013 |
Battinelli EM, Markens BA, Kulenthirarajan R, Machlus KR, Flaumenhaft R, Italiano JE. Anticoagulation Inhibits Tumor Cell-Mediated Release Of Platelet Angiogenic Proteins and Disrupts The Platelet Angiogenic Potential Blood. 122: 2303-2303. DOI: 10.1182/Blood.V122.21.2303.2303 |
0.479 |
|
| 2013 |
Peters CG, Gunnink S, Dilks JR, Dockendorff C, Flaumenhaft R. Effects Of Biased PAR1 Ligands On Platelets and Endothelial Cells Blood. 122: 23-23. DOI: 10.1182/Blood.V122.21.23.23 |
0.505 |
|
| 2013 |
Koseoglu S, Fitch-Tewfik JL, Peters CG, Danglot L, Galli T, Flaumenhaft RC. VAMP-7 Interacts With The Actin Cytoskeleton To Control Platelet Spreading and Mediate α-Granule Exocytosis During Thrombus Formation Blood. 122: 1058-1058. DOI: 10.1182/Blood.V122.21.1058.1058 |
0.39 |
|
| 2012 |
Flaumenhaft R. α-granules: a story in the making. Blood. 120: 4908-9. PMID 23243155 DOI: 10.1182/Blood-2012-10-459115 |
0.323 |
|
| 2012 |
Flaumenhaft R. Monitoring granule traffic in megakaryocytes. Blood. 120: 3869-70. PMID 23144159 DOI: 10.1182/Blood-2012-09-455121 |
0.391 |
|
| 2012 |
Peters CG, Michelson AD, Flaumenhaft R. Granule exocytosis is required for platelet spreading: differential sorting of α-granules expressing VAMP-7. Blood. 120: 199-206. PMID 22589474 DOI: 10.1182/Blood-2011-10-389247 |
0.412 |
|
| 2012 |
Jasuja R, Passam FH, Kennedy DR, Kim SH, van Hessem L, Lin L, Bowley SR, Joshi SS, Dilks JR, Furie B, Furie BC, Flaumenhaft R. Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents. The Journal of Clinical Investigation. 122: 2104-13. PMID 22565308 DOI: 10.1172/Jci61228 |
0.825 |
|
| 2012 |
Dockendorff C, Aisiku O, Verplank L, Dilks JR, Smith DA, Gunnink SF, Dowal L, Negri J, Palmer M, Macpherson L, Schreiber SL, Flaumenhaft R. Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor. Acs Medicinal Chemistry Letters. 3: 232-237. PMID 22408714 DOI: 10.1021/Ml2002696 |
0.443 |
|
| 2012 |
Dowal LM, Dilks JR, Fadel NA, Aisiku OR, Merrill-Skoloff G, Flaumenhaft RC. Acyl-Protein Thioesterase 1 Functions in Palmitoylation/Depalmitoylation Cycles of G Proteins and Regulates Platelet Activation Blood. 120: 1062-1062. DOI: 10.1182/Blood.V120.21.1062.1062 |
0.395 |
|
| 2011 |
Flaumenhaft R. Platelets get the message. Blood. 118: 1712-3. PMID 21852441 DOI: 10.1182/Blood-2011-06-359802 |
0.405 |
|
| 2011 |
Dowal L, Yang W, Freeman MR, Steen H, Flaumenhaft R. Proteomic analysis of palmitoylated platelet proteins. Blood. 118: e62-73. PMID 21813449 DOI: 10.1182/Blood-2011-05-353078 |
0.429 |
|
| 2011 |
Dowal L, Sim DS, Dilks JR, Blair P, Beaudry S, Denker BM, Koukos G, Kuliopulos A, Flaumenhaft R. Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1. Proceedings of the National Academy of Sciences of the United States of America. 108: 2951-6. PMID 21282664 DOI: 10.1073/Pnas.1014863108 |
0.443 |
|
| 2011 |
Liu J, Gao BB, Clermont AC, Blair P, Chilcote TJ, Sinha S, Flaumenhaft R, Feener EP. Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein. Nature Medicine. 17: 206-10. PMID 21258336 DOI: 10.1038/Nm.2295 |
0.433 |
|
| 2011 |
Nachtigall MJ, Jessel RH, Flaumenhaft R, Nachtigall R, Yoles I, Naftolin F, Nachtigall LE. The selective estrogen receptor modulator DT56a (Femarelle) does not affect platelet reactivity in normal or thrombophilic postmenopausal women. Menopause (New York, N.Y.). 18: 285-8. PMID 21037489 DOI: 10.1097/Gme.0B013E3181F2F01A |
0.326 |
|
| 2011 |
Flaumenhaft R. Sorting Out Platelet …-Granules The Hematologist. 8. DOI: 10.1182/hem.v8.6.1217 |
0.303 |
|
| 2011 |
Jasuja R, Passam FH, Kennedy DR, Kim SH, Hessem Lv, Lin L, Joshi SS, Dilks JR, Furie B, Furie BC, Flaumenhaft RC. Protein Disulfide Isomerase Inhibitors: A New Class of Antithrombotic Agents Blood. 118: 369-369. DOI: 10.1182/Blood.V118.21.369.369 |
0.618 |
|
| 2011 |
Flaumenhaft RC, Koseoglu S, Dilks JR, Peters CG, Fadel NA, Jasuja R, Haynes CL. Dynamin-Related Protein-1 Controls Fusion Pore Dynamics During Platelet Granule Secretion and Thrombus Formation In Vivo Blood. 118: 361-361. DOI: 10.1182/Blood.V118.21.361.361 |
0.358 |
|
| 2011 |
Flaumenhaft RC, Michelson AD, Peters CG. Platelet Spreading Requires Exocytosis of a Subpopulation of α-Granules Expressing VAMP-7, Blood. 118: 3248-3248. DOI: 10.1182/BLOOD.V118.21.3248.3248 |
0.309 |
|
| 2011 |
Aisiku OR, Dockendorff C, Gunnick SF, Smith DA, Dilks JR, Dowal LM, Flaumenhaft RC. An Allosteric Modulator of PAR1 Demonstrates Selective Inhibition of G Protein Coupling and Impairs Thrombus Formation In Vivo Blood. 118: 1138-1138. DOI: 10.1182/Blood.V118.21.1138.1138 |
0.381 |
|
| 2010 |
Flaumenhaft R. Filling a void in Gray Platelets. Blood. 116: 4738-40. PMID 21127182 DOI: 10.1182/Blood-2010-09-304378 |
0.33 |
|
| 2010 |
Flaumenhaft R, Mairuhu AT, Italiano JE. Platelet- and megakaryocyte-derived microparticles. Seminars in Thrombosis and Hemostasis. 36: 881-7. PMID 21049389 DOI: 10.1055/S-0030-1267042 |
0.44 |
|
| 2010 |
Italiano JE, Mairuhu AT, Flaumenhaft R. Clinical relevance of microparticles from platelets and megakaryocytes. Current Opinion in Hematology. 17: 578-84. PMID 20739880 DOI: 10.1097/Moh.0B013E32833E77Ee |
0.41 |
|
| 2010 |
Woronowicz K, Dilks JR, Rozenvayn N, Dowal L, Blair PS, Peters CG, Woronowicz L, Flaumenhaft R. The platelet actin cytoskeleton associates with SNAREs and participates in alpha-granule secretion. Biochemistry. 49: 4533-42. PMID 20429610 DOI: 10.1021/Bi100541T |
0.443 |
|
| 2010 |
Dowal L, Flaumenhaft R. Targeting platelet G-protein coupled receptors (GPCRs): looking beyond conventional GPCR antagonism. Current Vascular Pharmacology. 8: 140-54. PMID 19485898 DOI: 10.2174/157016110790886938 |
0.374 |
|
| 2010 |
Dowal LM, Sim D, Dilks JR, Blair P, Beaudry S, Denker B, Koukos G, Kuliopulos A, Flaumenhaft R. A Chemical Genetic Analysis of Platelet Activation Identifies An Antithrombotic Allosteric Modulator That Acts through Helix 8 of Par1 Blood. 116: 483-483. DOI: 10.1182/Blood.V116.21.483.483 |
0.475 |
|
| 2010 |
Flaumenhaft R, VerPlank L, Dilks JR, Smith DA, Blair P, Mairuhu AT, Negri J, Dockendorff C, McPherson L, Palmer M, Scheiber SL. Identification of a Novel Par1 inhibitor Using a Chemical Genetic Screen Blood. 116: 2018-2018. DOI: 10.1182/Blood.V116.21.2018.2018 |
0.461 |
|
| 2010 |
Peters CG, Flaumenhaft R. Localization of VAMP Isoforms In Platelets Reveals Separate Granule Populations with Distinct Functions Blood. 116: 2015-2015. DOI: 10.1182/Blood.V116.21.2015.2015 |
0.419 |
|
| 2009 |
Flaumenhaft R. Getting in shape with RanBP10. Blood. 114: 5412-3. PMID 20035043 DOI: 10.1182/Blood-2009-10-247528 |
0.4 |
|
| 2009 |
Blair P, Flaumenhaft R. Platelet alpha-granules: basic biology and clinical correlates. Blood Reviews. 23: 177-89. PMID 19450911 DOI: 10.1016/J.Blre.2009.04.001 |
0.35 |
|
| 2009 |
Graham GJ, Ren Q, Dilks JR, Blair P, Whiteheart SW, Flaumenhaft R. Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo. Blood. 114: 1083-90. PMID 19395672 DOI: 10.1182/Blood-2009-03-210211 |
0.452 |
|
| 2009 |
Flaumenhaft R, Nachtigall M, Lowenstein J, Nachtigall L, Nachtigall R, Nachtigall L. Association of oral but not transdermal estrogen therapy with enhanced platelet reactivity in a subset of postmenopausal women. Menopause (New York, N.Y.). 16: 407-12. PMID 18989235 DOI: 10.1097/Gme.0B013E3181833886 |
0.311 |
|
| 2009 |
Flaumenhaft R, Dilks JR, Richardson J, Alden E, Patel-Hett SR, Battinelli E, Klement GL, Sola-Visner M, Italiano JE. Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles. Blood. 113: 1112-21. PMID 18802008 DOI: 10.1182/Blood-2008-06-163832 |
0.457 |
|
| 2009 |
Flaumenhaft R, VerPlank L, Dilks JR, Blair PS, Mairuhu A, Negri J, Burbank J, Walzer G, Aldredge T, Dockendorff C, Gould R, MacPherson L, Palmer M. A Chemical Genetic Analysis of Platelet Activation. Blood. 114: 4009-4009. DOI: 10.1182/Blood.V114.22.4009.4009 |
0.388 |
|
| 2008 |
Flaumenhaft R, Dilks JR. Discovery-based strategies for studying platelet function. Mini-Reviews in Medicinal Chemistry. 8: 350-357. PMID 18473926 DOI: 10.2174/138955708783955971 |
0.469 |
|
| 2008 |
Dilks JR, Flaumenhaft R. Fluoxetine (Prozac) augments platelet activation mediated through protease-activated receptors. Journal of Thrombosis and Haemostasis. 6: 705-708. PMID 18194419 DOI: 10.1111/J.1538-7836.2008.02896.X |
0.421 |
|
| 2008 |
Flaumenhaft R, Dilks JR, Rozenvayn N, Woronowicz K. The Platelet Actin Cytoskeleton Associates Directly with Syntaxin-4 and Participates in α-Granule Secretion. Blood. 112: 1839-1839. DOI: 10.1182/Blood.V112.11.1839.1839 |
0.437 |
|
| 2008 |
Flaumenhaft R. Platelet proteoglycans packing it in Blood. 111: 3308-3309. DOI: 10.1182/Blood-2008-01-131870 |
0.405 |
|
| 2007 |
Flaumenhaft R, Rozenvayn N, Feng D, Dvorak AM. SNAP-23 and syntaxin-2 localize to the extracellular surface of the platelet plasma membrane. Blood. 110: 1492-501. PMID 17485553 DOI: 10.1182/Blood-2006-11-055772 |
0.422 |
|
| 2007 |
Sim DS, Dilks JR, Flaumenhaft R. Platelets possess and require an active protein palmitoylation pathway for agonist-mediated activation and in vivo thrombus formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1478-85. PMID 17303775 DOI: 10.1161/Atvbaha.106.139287 |
0.496 |
|
| 2007 |
Flaumenhaft R, Tanaka E, Graham GJ, De Grand AM, Laurence RG, Hoshino K, Hajjar RJ, Frangioni JV. Localization and quantification of platelet-rich thrombi in large blood vessels with near-infrared fluorescence imaging. Circulation. 115: 84-93. PMID 17179017 DOI: 10.1161/Circulationaha.106.643908 |
0.328 |
|
| 2007 |
Woronowicz K, Rozenvayn N, Flaumenhaft R. Platelet-Platelet Fusion Results from Fusing of Plasma Membranes and Is Augmented by Stimulation through PAR1 or CCR4. Blood. 110: 137-137. DOI: 10.1182/Blood.V110.11.137.137 |
0.444 |
|
| 2007 |
Flaumenhaft R, Rozenvayn N, Feng D, Dvorak AM. Response: Extracellular localization of platelet SNARE proteins Blood. 110: 3082-3083. DOI: 10.1182/Blood-2007-07-098376 |
0.363 |
|
| 2006 |
Flaumenhaft R. Formation and fate of platelet microparticles. Blood Cells, Molecules & Diseases. 36: 182-7. PMID 16466949 DOI: 10.1016/J.Bcmd.2005.12.019 |
0.447 |
|
| 2006 |
Graham GJ, Tanaka E, Grand AMD, Laurence RG, Hoshino K, Hajjar RJ, Frangioni JV, Flaumenhaft R. Real-Time Imaging of Platelet-Rich Thrombi in Thick-Walled Blood Vessels Using Near-Infrared Fluorescence Light. Blood. 108: 383-383. DOI: 10.1182/Blood.V108.11.383.383 |
0.437 |
|
| 2006 |
Flaumenhaft R, Dilks JR, Patel SR, Klement G, Italiano JE. Megakaryocyte-Derived Microparticles: Mechanism of Formation and Circulation in Plasma. Blood. 108: 1507-1507. DOI: 10.1182/Blood.V108.11.1507.1507 |
0.46 |
|
| 2005 |
Flaumenhaft R, Sim DS. Protein palmitoylation in signal transduction of hematopoietic cells. Hematology (Amsterdam, Netherlands). 10: 511-9. PMID 16321817 DOI: 10.1080/10245330500141507 |
0.351 |
|
| 2005 |
O'Connell DJ, Rozenvayn N, Flaumenhaft R. Phosphatidylinositol 4,5-bisphosphate regulates activation-induced platelet microparticle formation. Biochemistry. 44: 6361-70. PMID 15835925 DOI: 10.1021/Bi047344C |
0.494 |
|
| 2005 |
Sim DS, Flaumenhaft R, Furie BC, Furie B. Interactions of platelets, blood-borne tissue factor, and fibrin during arteriolar thrombus formation in vivo Microcirculation. 12: 301-311. PMID 15814438 DOI: 10.1080/10739680590925682 |
0.622 |
|
| 2005 |
Flaumenhaft R, Dilks JR, Rozenvayn N, Monahan-Earley RA, Feng D, Dvorak AM. The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretion. Blood. 105: 3879-87. PMID 15671445 DOI: 10.1182/Blood-2004-04-1392 |
0.424 |
|
| 2005 |
Flaumenhaft R, Dilks JR, Sim DS. Protein Palmitoylation in Platelet Function: Role in G Protein-Mediated Platelet Activation and Platelet Recruitment into Thrombi. Blood. 106: 650-650. DOI: 10.1182/Blood.V106.11.650.650 |
0.501 |
|
| 2005 |
Flaumenhaft R, Rozenvayn N, Feng D, Dvorak AM. SNARE Protein Distribution in Platelets: Extracellular Localization of SNAP-23 and Syntaxin 2. Blood. 106: 3566-3566. DOI: 10.1182/Blood.V106.11.3566.3566 |
0.459 |
|
| 2005 |
Flaumenhaft R. VPS33B: let there be α-granules Blood. 106: 4022-4023. DOI: 10.1182/Blood-2005-09-3928 |
0.301 |
|
| 2004 |
Flaumenhaft R. Platelet permeabilization. Methods in Molecular Biology (Clifton, N.J.). 273: 365-78. PMID 15308812 DOI: 10.1385/1-59259-783-1:365 |
0.306 |
|
| 2004 |
Falati S, Gross PL, Merrill-Skoloff G, Sim D, Flaumenhaft R, Celi A, Furie BC, Furie B. In vivo models of platelet function and thrombosis: study of real-time thrombus formation. Methods in Molecular Biology (Clifton, N.J.). 272: 187-97. PMID 15226545 DOI: 10.1385/1-59259-782-3:187 |
0.604 |
|
| 2004 |
Sim DS, Merrill-Skoloff G, Furie BC, Furie B, Flaumenhaft R. Initial accumulation of platelets during arterial thrombus formation in vivo is inhibited by elevation of basal cAMP levels. Blood. 103: 2127-34. PMID 14645013 DOI: 10.1182/Blood-2003-04-1133 |
0.652 |
|
| 2004 |
Flaumenhaft R, Dilks JR, Rozenvayn N, Monahan-Earley RA, Feng D, Dvorak AM. Differential Regulation of α-Granule and Dense Granule Secretion by an Actin Cytoskeletal Barrier. Blood. 104: 3528-3528. DOI: 10.1182/Blood.V104.11.3528.3528 |
0.361 |
|
| 2004 |
Sim DS, Peterson BR, Creaser SP, Flaumenhaft R. Protein Palmitoylation Participates in PAR1-Mediated Platelet Activation. Blood. 104: 1560-1560. DOI: 10.1182/Blood.V104.11.1560.1560 |
0.483 |
|
| 2004 |
Flaumenhaft R. Platelets feel your pain Blood. 104: 913-913. DOI: 10.1182/Blood-2004-05-1882 |
0.312 |
|
| 2003 |
Celi A, Merrill-Skoloff G, Gross P, Falati S, Sim DS, Flaumenhaft R, Furie BC, Furie B. Thrombus formation: Direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy Journal of Thrombosis and Haemostasis. 1: 60-68. PMID 12871540 DOI: 10.1046/J.1538-7836.2003.T01-1-00033.X |
0.575 |
|
| 2003 |
Flaumenhaft R, Sim DS. The platelet as a model for chemical genetics. Chemistry & Biology. 10: 481-6. PMID 12837380 DOI: 10.1016/S1074-5521(03)00127-3 |
0.306 |
|
| 2003 |
Flaumenhaft R. Molecular basis of platelet granule secretion. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1152-60. PMID 12738684 DOI: 10.1161/01.Atv.0000075965.88456.48 |
0.389 |
|
| 2003 |
Rozenvayn N, Flaumenhaft R. Protein kinase C mediates translocation of type II phosphatidylinositol 5-phosphate 4-kinase required for platelet alpha-granule secretion. The Journal of Biological Chemistry. 278: 8126-34. PMID 12509423 DOI: 10.1074/Jbc.M206493200 |
0.338 |
|
| 2003 |
Lai KC, Flaumenhaft R. SNARE protein degradation upon platelet activation: calpain cleaves SNAP-23. Journal of Cellular Physiology. 194: 206-14. PMID 12494459 DOI: 10.1002/Jcp.10222 |
0.456 |
|
| 2002 |
Feng D, Crane K, Rozenvayn N, Dvorak AM, Flaumenhaft R. Subcellular distribution of 3 functional platelet SNARE proteins: human cellubrevin, SNAP-23, and syntaxin 2. Blood. 99: 4006-14. PMID 12010801 DOI: 10.1182/Blood.V99.11.4006 |
0.397 |
|
| 2001 |
Rozenvayn N, Flaumenhaft R. Phosphatidylinositol 4,5-bisphosphate mediates Ca2+-induced platelet alpha-granule secretion: evidence for type II phosphatidylinositol 5-phosphate 4-kinase function. Journal of Biological Chemistry. 276: 22410-22419. PMID 11304526 DOI: 10.1074/Jbc.M008184200 |
0.338 |
|
| 2001 |
Furie B, Furie BC, Flaumenhaft R. A journey with platelet P-selectin: the molecular basis of granule secretion, signalling and cell adhesion. Thrombosis and Haemostasis. 86: 214-221. DOI: 10.1055/S-0037-1616219 |
0.615 |
|
| 1999 |
Yang J, Hirata T, Croce K, Merrill-Skoloff G, Tchernychev B, Williams E, Flaumenhaft R, Furie BC, Furie B. Targeted Gene Disruption Demonstrates That P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is Required for P-Selectin–Mediated but Not E-Selectin–Mediated Neutrophil Rolling and Migration Journal of Experimental Medicine. 190: 1769-1782. PMID 10601352 DOI: 10.1084/Jem.190.12.1769 |
0.55 |
|
| 1999 |
Croce K, Flaumenhaft R, Rivers M, Furie B, Furie BC, Herman IM, Potter DA. Inhibition of calpain blocks platelet secretion, aggregation, and spreading. The Journal of Biological Chemistry. 274: 36321-7. PMID 10593923 DOI: 10.1074/Jbc.274.51.36321 |
0.651 |
|
| 1999 |
Thorpe CM, Flaumenhaft R, Hurley B, Jacewicz M, Acheson DW, Keusch GT. Shiga toxins do not directly stimulate alpha-granule secretion or enhance aggregation of human platelets. Acta Haematologica. 102: 51-5. PMID 10473889 DOI: 10.1159/000040968 |
0.361 |
|
| 1999 |
Flaumenhaft R, Furie B, Furie BC. Alpha-granule secretion from alpha-toxin permeabilized, MgATP-exposed platelets is induced independently by H+ and Ca2+. Journal of Cellular Physiology. 179: 1-10. PMID 10082126 DOI: 10.1002/(Sici)1097-4652(199904)179:1<1::Aid-Jcp1>3.0.Co;2-E |
0.545 |
|
| 1999 |
Flaumenhaft R, Croce K, Chen E, Furie B, Furie BC. Proteins of the exocytotic core complex mediate platelet alpha-granule secretion. Roles of vesicle-associated membrane protein, SNAP-23, and syntaxin 4. Journal of Biological Chemistry. 274: 2492-2501. PMID 9891020 DOI: 10.1074/Jbc.274.4.2492 |
0.605 |
|
| 1992 |
Flaumenhaft R, Abe M, Mignatti P, Rifkin DB. Basic fibroblast growth factor-induced activation of latent transforming growth factor beta in endothelial cells: regulation of plasminogen activator activity. The Journal of Cell Biology. 118: 901-9. PMID 1380001 DOI: 10.1083/Jcb.118.4.901 |
0.3 |
|
| 1991 |
Flaumenhaft R, Rifkin DB. Extracellular matrix regulation of growth factor and protease activity Current Opinion in Cell Biology. 3: 817-823. PMID 1931082 DOI: 10.1016/0955-0674(91)90055-4 |
0.331 |
|
| 1990 |
Flaumenhaft R, Moscatelli D, Rifkin DB. Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor. Journal of Cell Biology. 111: 1651-1659. PMID 2170425 DOI: 10.1083/Jcb.111.4.1651 |
0.319 |
|
| 1990 |
Rifkin DB, Moscatelli D, Bizik J, Quarto N, Blei F, Dennis P, Flaumenhaft R, Mignatti P. Growth factor control of extracellular proteolysis. Cell Differentiation and Development : the Official Journal of the International Society of Developmental Biologists. 32: 313-8. PMID 1711916 DOI: 10.1016/0922-3371(90)90045-X |
0.336 |
|
| 1989 |
Flaumenhaft R, Moscatelli D, Saksela O, Rifkin DB. Role of extracellular matrix in the action of basic fibroblast growth factor: matrix as a source of growth factor for long-term stimulation of plasminogen activator production and DNA synthesis. Journal of Cellular Physiology. 140: 75-81. PMID 2738111 DOI: 10.1002/Jcp.1041400110 |
0.303 |
|
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