Matthew J. Ellis - Publications

Affiliations: 
Baylor College of Medicine, Houston, TX 

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lei JT, Jaehnig EJ, Smith H, Holt MV, Li X, Anurag M, Ellis MJ, Mills GB, Zhang B, Labrie M. The Breast Cancer Proteome and Precision Oncology. Cold Spring Harbor Perspectives in Medicine. PMID 37137501 DOI: 10.1101/cshperspect.a041323  0.337
2023 Gou X, Kim BJ, Anurag M, Lei JT, Young MN, Holt MV, Fandino D, Vollert CT, Singh P, Alzubi MA, Malovannaya A, Dobrolecki LE, Lewis MT, Li S, Foulds CE, ... Ellis MJ, et al. Kinome reprogramming is a targetable vulnerability in ESR1 fusion-driven breast cancer. Cancer Research. PMID 37071495 DOI: 10.1158/0008-5472.CAN-22-3484  0.301
2022 Anurag M, Jaehnig EJ, Krug K, Lei JT, Bergstrom EJ, Kim BJ, Vashist TD, Tran Huynh AM, Dou Y, Gou X, Huang C, Shi Z, Wen B, Korchina V, Gibbs RA, ... ... Ellis MJ, et al. Proteogenomic markers of chemotherapy resistance and response in triple negative breast cancer. Cancer Discovery. PMID 36001024 DOI: 10.1158/2159-8290.CD-22-0200  0.303
2022 Kalra R, Chen CH, Wang J, Salam AB, Dobrolecki LE, Lewis A, Sallas C, Yates CC, Gutierrez C, Karanam B, Anurag M, Lim B, Ellis MJ, Kavuri SM. Poziotinib inhibits HER2 mutant-driven therapeutic resistance and multi-organ metastasis in breast cancer. Cancer Research. PMID 35736563 DOI: 10.1158/0008-5472.CAN-21-3106  0.308
2022 Eteleeb AM, Thunuguntla PK, Gelev KZ, Tang CY, Rozycki EB, Miller A, Lei JT, Jayasinghe RG, Dang HX, White NM, Reis-Filho JS, Mardis ER, Ellis MJ, Ding L, Silva-Fisher JM, et al. LINC00355 regulates p27 expression by binding to MENIN to induce proliferation in late-stage relapse breast cancer. Npj Breast Cancer. 8: 49. PMID 35418131 DOI: 10.1038/s41523-022-00412-2  0.316
2021 Ademuyiwa FO, Chen I, Luo J, Rimawi MF, Hagemann IS, Fisk B, Jeffers G, Skidmore ZL, Basu A, Richters M, Ma CX, Weilbaecher K, Davis J, Suresh R, Peterson LL, ... ... Ellis MJ, et al. Immunogenomic profiling and pathological response results from a clinical trial of docetaxel and carboplatin in triple-negative breast cancer. Breast Cancer Research and Treatment. PMID 34173924 DOI: 10.1007/s10549-021-06307-3  0.302
2021 Punturi NB, Seker S, Devarakonda V, Mazumder A, Kalra R, Chen CH, Li S, Primeau T, Ellis MJ, Kavuri SM, Haricharan S. Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer. Nature Communications. 12: 2940. PMID 34011995 DOI: 10.1038/s41467-021-23271-0  0.309
2021 Watt AC, Cejas P, DeCristo MJ, Metzger-Filho O, Lam EYN, Qiu X, BrinJones H, Kesten N, Coulson R, Font-Tello A, Lim K, Vadhi R, Daniels VW, Montero J, Taing L, ... ... Ellis MJ, et al. CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity. Nature Cancer. 2: 34-48. PMID 33997789 DOI: 10.1038/s43018-020-00135-y  0.309
2021 Wang X, Veeraraghavan J, Liu CC, Cao X, Qin L, Kim JA, Tan Y, Loo SK, Hu Y, Lin L, Lee S, Shea M, Mitchell T, Li S, Ellis MJ, et al. Therapeutic targeting of nemo-like kinase in primary and acquired endocrine-resistant breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33542078 DOI: 10.1158/1078-0432.CCR-20-2961  0.321
2021 Bowling EA, Wang JH, Gong F, Wu W, Neill NJ, Kim IS, Tyagi S, Orellana M, Kurley SJ, Dominguez-Vidaña R, Chung HC, Hsu TY, Dubrulle J, Saltzman AB, Li H, ... ... Ellis MJ, et al. Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer. Cell. PMID 33450205 DOI: 10.1016/j.cell.2020.12.031  0.531
2020 Guo Z, Primeau T, Luo J, Zhang C, Sun H, Hoog J, Gao F, Huang S, Edwards DP, Davies SR, Aft R, Ding L, Ellis MJ, Li S, Ma CX. Proteomic Resistance Biomarkers for PI3K Inhibitor in Triple Negative Breast Cancer Patient-Derived Xenograft Models. Cancers. 12. PMID 33371187 DOI: 10.3390/cancers12123857  0.308
2020 Nielsen TO, Leung SCY, Rimm DL, Dodson A, Acs B, Badve S, Denkert C, Ellis MJ, Fineberg S, Flowers M, Kreipe HH, Laenkholm AV, Pan H, Penault-Llorca FM, Polley MY, et al. Assessment of Ki67 in Breast Cancer: Updated Recommendations from the International Ki67 in Breast Cancer Working Group. Journal of the National Cancer Institute. PMID 33369635 DOI: 10.1093/jnci/djaa201  0.301
2020 Dustin D, Gu G, Beyer AR, Herzog SK, Edwards DG, Lin H, Gonzalez TL, Grimm SL, Coarfa C, Chan DW, Kim BJ, De La O JP, Ellis MJ, Liu D, Li S, et al. RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer. British Journal of Cancer. PMID 33257837 DOI: 10.1038/s41416-020-01174-z  0.34
2020 Krug K, Jaehnig EJ, Satpathy S, Blumenberg L, Karpova A, Anurag M, Miles G, Mertins P, Geffen Y, Tang LC, Heiman DI, Cao S, Maruvka YE, Lei JT, Huang C, ... ... Ellis MJ, et al. Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy. Cell. PMID 33212010 DOI: 10.1016/j.cell.2020.10.036  0.376
2020 Cairns J, Ingle JN, Dudenkov TTM, Kalari KR, Carlson EE, Na J, Buzdar AU, Robson ME, Ellis MJ, Goss PE, Shepherd LE, Goodnature B, Goetz MP, Weinshilboum RM, Li H, et al. Pharmacogenomics of aromatase inhibitors in postmenopausal breast cancer and additional mechanisms of anastrozole action. Jci Insight. PMID 32701512 DOI: 10.1172/Jci.Insight.137571  0.329
2020 Zheng ZY, Anurag M, Lei JT, Cao J, Singh P, Peng J, Kennedy H, Nguyen NC, Chen Y, Lavere P, Li J, Du XH, Cakar B, Song W, Kim BJ, ... ... Ellis MJ, et al. Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer. Cancer Cell. PMID 32142667 DOI: 10.1016/J.Ccell.2020.02.003  0.326
2020 Satpathy S, Jaehnig EJ, Krug K, Kim BJ, Saltzman AB, Chan DW, Holloway KR, Anurag M, Huang C, Singh P, Gao A, Namai N, Dou Y, Wen B, Vasaikar SV, ... ... Ellis MJ, et al. Microscaled proteogenomic methods for precision oncology. Nature Communications. 11: 532. PMID 31988290 DOI: 10.1038/S41467-020-14381-2  0.318
2019 Anurag M, Zhu M, Huang C, Vasaikar S, Wang J, Hoog J, Burugu S, Gao D, Suman V, Zhang XH, Zhang B, Nielsen T, Ellis MJ. Immune Checkpoint Profiles in Luminal B Breast Cancer (Alliance). Journal of the National Cancer Institute. PMID 31665365 DOI: 10.1093/Jnci/Djz213  0.313
2019 Sparano JA, Gray RJ, Makower DF, Albain KS, Saphner TJ, Badve SS, Wagner LI, Kaklamani VG, Keane MM, Gomez HL, Reddy PS, Goggins TF, Mayer IA, Toppmeyer DL, Brufsky AM, ... ... Ellis MJ, et al. Clinical Outcomes in Early Breast Cancer With a High 21-Gene Recurrence Score of 26 to 100 Assigned to Adjuvant Chemotherapy Plus Endocrine Therapy: A Secondary Analysis of the TAILORx Randomized Clinical Trial. Jama Oncology. PMID 31566680 DOI: 10.1001/Jamaoncol.2019.4794  0.31
2019 Pu M, Messer K, Davies SR, Vickery TL, Pittman E, Parker BA, Ellis MJ, Flatt SW, Marinac CR, Nelson SH, Mardis ER, Pierce JP, Natarajan L. Research-based PAM50 signature and long-term breast cancer survival. Breast Cancer Research and Treatment. PMID 31542876 DOI: 10.1007/s10549-019-05446-y  0.308
2019 Cheng AS, Leung SCY, Gao D, Burugu S, Anurag M, Ellis MJ, Nielsen TO. Mismatch repair protein loss in breast cancer: clinicopathological associations in a large British Columbia cohort. Breast Cancer Research and Treatment. PMID 31522348 DOI: 10.1007/s10549-019-05438-y  0.31
2019 Lei JT, Gou X, Seker S, Ellis MJ. alterations and metastasis in estrogen receptor positive breast cancer. Journal of Cancer Metastasis and Treatment. 5. PMID 31106278 DOI: 10.20517/2394-4722.2019.12  0.345
2018 Lei JT, Gou X, Ellis MJ. fusions drive endocrine therapy resistance and metastasis in breast cancer. Molecular & Cellular Oncology. 5: e1526005. PMID 30525098 DOI: 10.1080/23723556.2018.1526005  0.331
2018 Matsunuma R, Chan DW, Kim BJ, Singh P, Han A, Saltzman AB, Cheng C, Lei JT, Wang J, Roberto da Silva L, Sahin E, Leng M, Fan C, Perou CM, Malovannaya A, ... Ellis MJ, et al. DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 30498031 DOI: 10.1073/Pnas.1810598115  0.347
2018 Kim J, Piao HL, Kim BJ, Yao F, Han Z, Wang Y, Xiao Z, Siverly AN, Lawhon SE, Ton BN, Lee H, Zhou Z, Gan B, Nakagawa S, Ellis MJ, et al. Long noncoding RNA MALAT1 suppresses breast cancer metastasis. Nature Genetics. PMID 30349115 DOI: 10.1038/S41588-018-0252-3  0.36
2018 Reinert T, de Paula B, Shafaee MN, Souza PH, Ellis MJ, Bines J. Endocrine therapy for ER-positive/HER2-negative metastatic breast cancer. Chinese Clinical Oncology. 7: 25. PMID 30056727 DOI: 10.21037/cco.2018.06.06  0.354
2018 Nguyen TM, Kabotyanski EB, Dou Y, Reineke LC, Zhang P, Zhang XH, Malovannaya A, Jung SY, Mo Q, Roarty KP, Chen Y, Zhang B, Neilson JR, Lloyd RE, Perou CM, ... Ellis MJ, et al. FGFR1-activated Translation of WNT Pathway Components with Structured 5' UTRs is Vulnerable to Inhibition of EIF4A-dependent Translation Initiation. Cancer Research. PMID 29844125 DOI: 10.1158/0008-5472.Can-18-0631  0.5
2018 Reinert T, Gonçalves R, Ellis MJ. Current Status of Neoadjuvant Endocrine Therapy in Early Stage Breast Cancer. Current Treatment Options in Oncology. 19: 23. PMID 29663173 DOI: 10.1007/s11864-018-0538-9  0.314
2018 Nair A, Chung HC, Sun T, Tyagi S, Dobrolecki LE, Dominguez-Vidana R, Kurley SJ, Orellana M, Renwick A, Henke DM, Katsonis P, Schmitt E, Chan DW, Li H, Mao S, ... ... Ellis MJ, et al. Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer. Nature Medicine. PMID 29578538 DOI: 10.1038/Nm.4507  0.31
2017 Doostan I, Karakas C, Kohansal M, Low KH, Ellis MJ, Olson JA, Suman V, Hunt K, Moulder-Thompson S, Keyomarsi K. Cytoplasmic Cyclin E Mediates Resistance to Aromatase Inhibitors in Breast Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28947566 DOI: 10.1158/1078-0432.Ccr-17-1544  0.314
2017 Ma CX, Suman V, Goetz MP, Northfelt DW, Burkard ME, Ademuyiwa F, Naughton MJ, Margenthaler J, Aft R, Gray RJ, Tevaarwerk AJ, Wilke LG, Haddad TC, Moynihan T, Loprenzi C, ... ... Ellis MJ, et al. A Phase II trial of neoadjuvant MK2206, an AKT inhibitor, with anastrozole in clinical stage 2 or 3 PIK3CA mutant ER positive and HER2 negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28874413 DOI: 10.1158/1078-0432.Ccr-17-1260  0.313
2017 Haricharan S, Punturi N, Singh P, Holloway KR, Anurag M, Schmelz J, Schmidt C, Lei JT, Suman V, Hunt K, Olson JA, Hoog J, Li S, Huang S, Edwards DP, ... ... Ellis MJ, et al. Loss of MutL Disrupts Chk2-dependent Cell Cycle Control Through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer. Cancer Discovery. PMID 28801307 DOI: 10.1158/2159-8290.Cd-16-1179  0.33
2017 Ellis MJ. Lessons in precision oncology from neoadjuvant endocrine therapy trials in ER+ breast cancer. Breast (Edinburgh, Scotland). PMID 28669712 DOI: 10.1016/j.breast.2017.06.039  0.322
2017 Zhang X, Kim S, Hundal J, Herndon JM, Li S, Petti AA, Soysal SD, Li L, McLellan MD, Hoog J, Primeau T, Myers N, Vickery TL, Sturmoski M, Hagemann IS, ... ... Ellis MJ, et al. Breast cancer neoantigens can induce CD8 T cell responses and antitumor immunity. Cancer Immunology Research. PMID 28619968 DOI: 10.1158/2326-6066.Cir-16-0264  0.323
2017 Shafaee MN, Ellis MJ. Breast Cancer Patient-Derived Xenografts: Pros, Cons, and Next Steps. Journal of the National Cancer Institute. 109. PMID 28376181 DOI: 10.1093/jnci/djw307  0.303
2017 Ma CX, Gao F, Luo J, Northfelt DW, Goetz MP, Forero A, Hoog J, Naughton MJ, Ademuyiwa F, Suresh R, Anderson KS, Margenthaler J, Aft R, Hobday TJ, Moynihan T, ... ... Ellis MJ, et al. NeoPalAna: Neoadjuvant palbociclib, a cyclin-dependent kinase 4/6 inhibitor, and anastrozole for clinical stage 2 or 3 estrogen receptor positive breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28270497 DOI: 10.1158/1078-0432.Ccr-16-3206  0.313
2017 Bai L, Zhou B, Yang CY, Ji J, McEachern D, Przybranowski S, Jiang H, Hu J, Xu F, Zhao Y, Liu L, Fernandez-Salas E, Xu J, Dou Y, Wen B, ... ... Ellis MJ, et al. Targeted degradation of BET proteins in triple-negative breast cancer. Cancer Research. PMID 28209615 DOI: 10.1158/0008-5472.Can-16-2622  0.351
2016 Dobrolecki LE, Airhart SD, Alferez DG, Aparicio S, Behbod F, Bentires-Alj M, Brisken C, Bult CJ, Cai S, Clarke RB, Dowst H, Ellis MJ, Gonzalez-Suarez E, Iggo RD, Kabos P, et al. Patient-derived xenograft (PDX) models in basic and translational breast cancer research. Cancer Metastasis Reviews. PMID 28025748 DOI: 10.1007/S10555-016-9653-X  0.304
2016 Lu J, McEachern D, Li S, Ellis MJ, Wang S. Reactivation of p53 by MDM2 inhibitor MI-77301 for the treatment of endocrine-resistant breast cancer. Molecular Cancer Therapeutics. PMID 27765850 DOI: 10.1158/1535-7163.Mct-16-0028  0.316
2016 Ingle JN, Xie F, Ellis MJ, Goss PE, Shepherd LE, Chapman JW, Chen BE, Kubo M, Furukawa Y, Momozawa Y, Stearns V, Pritchard KI, Barman P, Carlson EE, Goetz MP, et al. Genetic polymorphisms in the long noncoding RNA MIR2052HG offer a pharmacogenomic basis for the response of breast cancer patients to aromatase inhibitor therapy. Cancer Research. PMID 27758888 DOI: 10.1158/0008-5472.Can-16-1371  0.349
2016 Mertins P, Mani DR, Ruggles KV, Gillette MA, Clauser KR, Wang P, Wang X, Qiao JW, Cao S, Petralia F, Kawaler E, Mundt F, Krug K, Tu Z, Lei JT, ... ... Ellis MJ, et al. Proteogenomics connects somatic mutations to signalling in breast cancer. Nature. 534: 55-62. PMID 27251275 DOI: 10.1038/Nature18003  0.326
2016 Krop IE, Mayer IA, Ganju V, Dickler M, Johnston S, Morales S, Yardley DA, Melichar B, Forero-Torres A, Lee SC, de Boer R, Petrakova K, Vallentin S, Perez EA, Piccart M, ... Ellis M, et al. Pictilisib for oestrogen receptor-positive, aromatase inhibitor-resistant, advanced or metastatic breast cancer (FERGI): a randomised, double-blind, placebo-controlled, phase 2 trial. The Lancet. Oncology. PMID 27155741 DOI: 10.1016/S1470-2045(16)00106-6  0.317
2016 Ma CX, Bose R, Ellis MJ. Prognostic and Predictive Biomarkers of Endocrine Responsiveness for Estrogen Receptor Positive Breast Cancer. Advances in Experimental Medicine and Biology. 882: 125-54. PMID 26987533 DOI: 10.1007/978-3-319-22909-6_5  0.322
2016 Haricharan S, Lei J, Ellis M. Mammary Ductal Environment Is Necessary for Faithful Maintenance of Estrogen Signaling in ER(+) Breast Cancer. Cancer Cell. 29: 249-250. PMID 26977876 DOI: 10.1016/j.ccell.2016.02.017  0.331
2016 Chimge NO, Little GH, Baniwal SK, Adisetiyo H, Xie Y, Zhang T, O'Laughlin A, Liu ZY, Ulrich P, Martin A, Mhawech-Fauceglia P, Ellis MJ, Tripathy D, Groshen S, Liang C, et al. RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer. Nature Communications. 7: 10751. PMID 26916619 DOI: 10.1038/Ncomms10751  0.321
2016 Ma CX, Sanchez C, Gao F, Crowder R, Naughton M, Pluard T, Creekmore A, Guo Z, Hoog J, Lockhart AC, Doyle A, Erlichman C, Ellis MJ. A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor Positive Metastatic Breast Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26783290 DOI: 10.1158/1078-0432.CCR-15-2160  0.323
2015 Ben-Baruch NE, Bose R, Kavuri SM, Ma CX, Ellis MJ. HER2-Mutated Breast Cancer Responds to Treatment With Single-Agent Neratinib, a Second-Generation HER2/EGFR Tyrosine Kinase Inhibitor. Journal of the National Comprehensive Cancer Network : Jnccn. 13: 1061-4. PMID 26358790 DOI: 10.6004/Jnccn.2015.0131  0.324
2015 Wardell SE, Ellis MJ, Alley HM, Eisele K, VanArsdale T, Dann SG, Arndt KT, Primeau T, Griffin E, Shao J, Crowder RJ, Lai JP, Norris JD, McDonnell DP, Li S. Efficacy of SERD/SERM Hybrid-CDK4/6 inhibitor combinations in models of endocrine therapy resistant breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 25991817 DOI: 10.1158/1078-0432.Ccr-15-0360  0.316
2015 Tolaney SM, Barry WT, Dang CT, Yardley DA, Moy B, Marcom PK, Albain KS, Rugo HS, Ellis M, Shapira I, Wolff AC, Carey LA, Overmoyer BA, Partridge AH, Guo H, et al. Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer. The New England Journal of Medicine. 372: 134-41. PMID 25564897 DOI: 10.1056/Nejmoa1406281  0.314
2015 Xu Z, Wu C, Xie F, Slysz GW, Tolic N, Monroe ME, Petyuk VA, Payne SH, Fujimoto GM, Moore RJ, Fillmore TL, Schepmoes AA, Levine DA, Townsend RR, Davies SR, ... ... Ellis M, et al. Comprehensive quantitative analysis of ovarian and breast cancer tumor peptidomes. Journal of Proteome Research. 14: 422-33. PMID 25350482 DOI: 10.1021/Pr500840W  0.303
2014 Goncalves R, Warner WA, Luo J, Ellis MJ. New concepts in breast cancer genomics and genetics. Breast Cancer Research : Bcr. 16: 460. PMID 25606588 DOI: 10.1186/s13058-014-0460-4  0.33
2014 Barbie TU, Alexe G, Aref AR, Li S, Zhu Z, Zhang X, Imamura Y, Thai TC, Huang Y, Bowden M, Herndon J, Cohoon TJ, Fleming T, Tamayo P, Mesirov JP, ... ... Ellis MJ, et al. Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth. The Journal of Clinical Investigation. 124: 5411-23. PMID 25365225 DOI: 10.1172/Jci75661  0.354
2014 Ellis MJ. HER2-positive breast cancer, intrinsic subtypes, and tailoring therapy. Journal of the National Cancer Institute. 106. PMID 25139535 DOI: 10.1093/jnci/dju212  0.305
2014 Ellis MJ. Mutational analysis of breast cancer: guiding personalized treatments. Breast (Edinburgh, Scotland). S19-21. PMID 24074785 DOI: 10.1016/j.breast.2013.07.003  0.332
2013 Buzdar AU, Suman VJ, Meric-Bernstam F, Leitch AM, Ellis MJ, Boughey JC, Unzeitig G, Royce M, McCall LM, Ewer MS, Hunt KK. Fluorouracil, epirubicin, and cyclophosphamide (FEC-75) followed by paclitaxel plus trastuzumab versus paclitaxel plus trastuzumab followed by FEC-75 plus trastuzumab as neoadjuvant treatment for patients with HER2-positive breast cancer (Z1041): a randomised, controlled, phase 3 trial. The Lancet. Oncology. 14: 1317-25. PMID 24239210 DOI: 10.1016/S1470-2045(13)70502-3  0.3
2013 Ademuyiwa FO, Ellis MJ, Ma CX. Neoadjuvant therapy in operable breast cancer: application to triple negative breast cancer. Journal of Oncology. 2013: 219869. PMID 23983689 DOI: 10.1155/2013/219869  0.308
2013 Won JR, Gao D, Chow C, Cheng J, Lau SY, Ellis MJ, Perou CM, Bernard PS, Nielsen TO. A survey of immunohistochemical biomarkers for basal-like breast cancer against a gene expression profile gold standard. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 26: 1438-50. PMID 23702728 DOI: 10.1038/Modpathol.2013.97  0.339
2013 Xu S, Li S, Guo Z, Luo J, Ellis MJ, Ma CX. Combined targeting of mTOR and AKT Is an effective strategy for basal-like breast cancer in patient-derived xenograft models Molecular Cancer Therapeutics. 12: 1665-1675. PMID 23689832 DOI: 10.1158/1535-7163.MCT-13-0159  0.375
2013 Ellis MJ, Perou CM. The genomic landscape of breast cancer as a therapeutic roadmap. Cancer Discovery. 3: 27-34. PMID 23319768 DOI: 10.1158/2159-8290.Cd-12-0462  0.349
2012 Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Wallis JW, Van Tine BA, Hoog J, Goiffon RJ, Goldstein TC, Ng S, Lin L, Crowder R, Snider J, Ballman K, et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature. 486: 353-60. PMID 22722193 DOI: 10.1038/Nature11143  0.309
2012 Fleming GF, Ma CX, Huo D, Sattar H, Tretiakova M, Lin L, Hahn OM, Olopade FO, Nanda R, Hoffman PC, Naughton MJ, Pluard T, Conzen SD, Ellis MJ. Phase II trial of temsirolimus in patients with metastatic breast cancer. Breast Cancer Research and Treatment. 136: 355-63. PMID 22245973 DOI: 10.1007/S10549-011-1910-7  0.304
2012 Chimge NO, Baniwal SK, Luo J, Coetzee S, Khalid O, Berman BP, Tripathy D, Ellis MJ, Frenkel B. Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 901-11. PMID 22147940 DOI: 10.1158/1078-0432.Ccr-11-1530  0.334
2012 Prat A, Ellis MJ, Perou CM. Practical implications of gene-expression-based assays for breast oncologists. Nature Reviews. Clinical Oncology. 9: 48-57. PMID 22143140 DOI: 10.1038/Nrclinonc.2011.178  0.325
2012 Ma CX, Luo J, Ellis MJ. Molecular profiling of triple negative breast cancer. Breast Disease. 32: 73-84. PMID 21778575 DOI: 10.3233/BD-2010-0309  0.324
2011 Peddi PF, Ellis MJ, Ma C. Molecular basis of triple negative breast cancer and implications for therapy. International Journal of Breast Cancer. 2012: 217185. PMID 22295242 DOI: 10.1155/2012/217185  0.353
2011 Roop RP, Ma CX, Ellis MJ. PARP inhibitors and their evolving role in breast cancer. Oncology (Williston Park, N.Y.). 25: 1033-4. PMID 22106554  0.312
2011 Van Tine BA, Crowder RJ, Ellis MJ. ER and PI3K independently modulate endocrine resistance in ER-positive breast cancer. Cancer Discovery. 1: 287-8. PMID 22096658 DOI: 10.1158/2159-8290.CD-11-0192  0.34
2011 Dowsett M, Nielsen TO, A'Hern R, Bartlett J, Coombes RC, Cuzick J, Ellis M, Henry NL, Hugh JC, Lively T, McShane L, Paik S, Penault-Llorca F, Prudkin L, Regan M, et al. Assessment of Ki67 in breast cancer: recommendations from the International Ki67 in Breast Cancer working group. Journal of the National Cancer Institute. 103: 1656-64. PMID 21960707 DOI: 10.1093/jnci/djr393  0.319
2011 Ma CX, Crowder RJ, Ellis MJ. Importance of PI3-kinase pathway in response/resistance to aromatase inhibitors. Steroids. 76: 750-2. PMID 21420991 DOI: 10.1016/j.steroids.2011.02.023  0.37
2011 Sanchez CG, Ma CX, Crowder RJ, Guintoli T, Phommaly C, Gao F, Lin L, Ellis MJ. Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer. Breast Cancer Research : Bcr. 13: R21. PMID 21362200 DOI: 10.1186/bcr2833  0.31
2009 Graveel CR, DeGroot JD, Su Y, Koeman J, Dykema K, Leung S, Snider J, Davies SR, Swiatek PJ, Cottingham S, Watson MA, Ellis MJ, Sigler RE, Furge KA, Vande Woude GF. Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 106: 12909-14. PMID 19567831 DOI: 10.1073/pnas.0810403106  0.365
2009 Toi M, Sasano H, Ellis MJ. [Future prospects of neoadjuvant endocrine therapy in postmenopausal breast cancer]. Gan to Kagaku Ryoho. Cancer & Chemotherapy. 36: 1035-42. PMID 19542732  0.324
2009 Cheang MC, Chia SK, Voduc D, Gao D, Leung S, Snider J, Watson M, Davies S, Bernard PS, Parker JS, Perou CM, Ellis MJ, Nielsen TO. Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. Journal of the National Cancer Institute. 101: 736-50. PMID 19436038 DOI: 10.1093/Jnci/Djp082  0.324
2009 Crowder RJ, Phommaly C, Tao Y, Hoog J, Luo J, Perou CM, Parker JS, Miller MA, Huntsman DG, Lin L, Snider J, Davies SR, Olson JA, Watson MA, Saporita A, ... ... Ellis MJ, et al. PIK3CA and PIK3CB inhibition produce synthetic lethality when combined with estrogen deprivation in estrogen receptor-positive breast cancer. Cancer Research. 69: 3955-62. PMID 19366795 DOI: 10.1158/0008-5472.Can-08-4450  0.351
2009 Ma CX, Sanchez CG, Ellis MJ. Predicting endocrine therapy responsiveness in breast cancer. Oncology (Williston Park, N.Y.). 23: 133-42. PMID 19323294  0.33
2008 Ellis MJ, Tao Y, Luo J, A'Hern R, Evans DB, Bhatnagar AS, Chaudri Ross HA, von Kameke A, Miller WR, Smith I, Eiermann W, Dowsett M. Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics. Journal of the National Cancer Institute. 100: 1380-8. PMID 18812550 DOI: 10.1093/jnci/djn309  0.311
2007 Ellis MJ, Ma C. Letrozole in the neoadjuvant setting: the P024 trial. Breast Cancer Research and Treatment. 33-43. PMID 17912634 DOI: 10.1007/s10549-007-9701-x  0.331
2006 Marcom PK, Isaacs C, Harris L, Wong ZW, Kommarreddy A, Novielli N, Mann G, Tao Y, Ellis MJ. The combination of letrozole and trastuzumab as first or second-line biological therapy produces durable responses in a subset of HER2 positive and ER positive advanced breast cancers. Breast Cancer Research and Treatment. 102: 43-9. PMID 16897431 DOI: 10.1007/s10549-006-9307-8  0.301
2005 Crowder RJ, Ellis MJ. Treating breast cancer through novel inhibitors of the phosphatidylinositol 3'-kinase pathway. Breast Cancer Research : Bcr. 7: 212-4. PMID 16168140 DOI: 10.1186/bcr1307  0.352
2005 Ellis MJ. Neoadjuvant endocrine therapy for breast cancer: more questions than answers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 4842-4. PMID 15998901 DOI: 10.1200/JCO.2005.92.003  0.306
2004 Crowder RJ, Lombardi DP, Ellis MJ. Successful targeting of ErbB2 receptors-is PTEN the key? Cancer Cell. 6: 103-4. PMID 15324690 DOI: 10.1016/j.ccr.2004.08.001  0.311
2004 Cristofanilli M, Budd GT, Ellis MJ, Stopeck A, Matera J, Miller MC, Reuben JM, Doyle GV, Allard WJ, Terstappen LW, Hayes DF. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. The New England Journal of Medicine. 351: 781-91. PMID 15317891 DOI: 10.1056/NEJMoa040766  0.303
2004 Dougherty MK, Schumaker LM, Jordan VC, Welshons WV, Curran EM, Ellis MJ, El-Ashry D. Estrogen receptor expression and sensitivity to paclitaxel in breast cancer. Cancer Biology & Therapy. 3: 460-7. PMID 15020841 DOI: 10.4161/Cbt.3.5.810  0.315
2004 Wong ZW, Phillips SJ, Ellis MJ. Dramatic Response of Choroidal Metastases from Breast Cancer to a Combination of Trastuzumab and Vinorelbine Breast Journal. 10: 54-56. PMID 14717761 DOI: 10.1111/j.1524-4741.2004.09614.x  0.315
2004 Ellis MJ. Breast cancer gene expression analysis--the case for dynamic profiling. Advances in Experimental Medicine and Biology. 532: 223-34. PMID 12908561  0.333
2004 Dowsett M, Ellis MJ. Role of biologic markers in patient selection and application to disease prevention. American Journal of Clinical Oncology. 26: S34-9. PMID 12902875 DOI: 10.1097/00000421-200308001-00006  0.343
2003 Ellis MJ, Coop A, Singh B, Tao Y, Llombart-Cussac A, Jänicke F, Mauriac L, Quebe-Fehling E, Chaudri-Ross HA, Evans DB, Miller WR. Letrozole inhibits tumor proliferation more effectively than tamoxifen independent of HER1/2 expression status. Cancer Research. 63: 6523-31. PMID 14559846  0.311
2002 Shaw HS, Ellis MJ. Letrozole in the treatment of breast cancer. Expert Opinion On Pharmacotherapy. 3: 607-17. PMID 11996638 DOI: 10.1517/14656566.3.5.607  0.318
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