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Manuel Yepes - Publications

Affiliations: 
Neurology Emory University, Atlanta, GA 
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Diaz A, Merino P, McCann P, Yepes MA, Quiceno LG, Torre E, Tomkins A, Zhang X, Hales CM, Tong FC, Yepes M. Urokinase-type plasminogen activator promotes N-cadherin-mediated synaptic recovery in the ischemic brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211002297. PMID 33757316 DOI: 10.1177/0271678X211002297  0.444
2020 Diaz A, Merino P, Guo JD, Yepes MA, McCann P, Katta T, Tong EM, Torre E, Rangaraju S, Yepes M. Urokinase-type Plasminogen Activator Protects Cerebral Cortical Neurons From Soluble Aβ-induced Synaptic Damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32332118 DOI: 10.1523/JNEUROSCI.2804-19.2020  0.308
2019 Merino P, Diaz A, Torre ER, Yepes M. Urokinase-type Plasminogen Activator (uPA) Regulates the Expression and Function of the Growth- associated Protein-43 (GAP-43) in the Synapse. The Journal of Biological Chemistry. PMID 31819012 DOI: 10.1074/jbc.RA119.010644  0.354
2019 Diaz A, Jeanneret V, Merino P, McCann P, Yepes M. Tissue-type plasminogen activator regulates p35-mediated Cdk5 activation in the postsynaptic terminal. Journal of Cell Science. PMID 30709918 DOI: 10.1242/jcs.224196  0.392
2018 Diaz A, Merino P, Manrique LG, Cheng L, Yepes M. Urokinase-type plasminogen activator (uPA) protects the tripartite synapse in the ischemic brain via ezrin-mediated formation of peripheral astrocytic processes. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18783653. PMID 29890880 DOI: 10.1177/0271678X18783653  0.442
2018 Merino P, Diaz A, Manrique LG, Cheng L, Yepes M. Urokinase-type plasminogen activator (uPA) promotes ezrin-mediated reorganization of the synaptic cytoskeleton in the ischemic brain. The Journal of Biological Chemistry. PMID 29720403 DOI: 10.1074/jbc.RA118.002534  0.437
2018 Diaz A, Yepes M. Urokinase-type plasminogen activator promotes synaptic repair in the ischemic brain. Neural Regeneration Research. 13: 232-233. PMID 29557368 DOI: 10.4103/1673-5374.226384  0.303
2018 Jeanneret V, Ospina JP, Diaz A, Manrique LG, Merino P, Gutierrez L, Torre E, Wu F, Cheng L, Yepes M. Tissue-type plasminogen activator protects the postsynaptic density in the ischemic brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18764495. PMID 29547062 DOI: 10.1177/0271678X18764495  0.392
2017 Diaz A, Merino P, Manrique LG, Ospina JP, Cheng L, Wu F, Jeanneret V, Yepes M. A Cross-talk Between Neuronal Urokinase-type Plasminogen Activator (uPA) and Astrocytic uPA Receptor (uPAR) Promotes Astrocytic Activation and Synaptic Recovery in the Ischemic Brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28931568 DOI: 10.1523/JNEUROSCI.1630-17.2017  0.496
2017 Su EJ, Cao C, Fredriksson L, Nilsson I, Stefanitsch C, Stevenson TK, Zhao J, Ragsdale M, Sun YY, Yepes M, Kuan CY, Eriksson U, Strickland DK, Lawrence DA, Zhang L. Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke. Acta Neuropathologica. PMID 28725968 DOI: 10.1007/S00401-017-1749-Z  0.345
2016 Jeanneret V, Wu F, Merino P, Torre E, Diaz A, Cheng L, Yepes M. Tissue-type Plasminogen Activator (tPA) Modulates the Postsynaptic Response of Cerebral Cortical Neurons to the Presynaptic Release of Glutamate. Frontiers in Molecular Neuroscience. 9: 121. PMID 27881952 DOI: 10.3389/fnmol.2016.00121  0.471
2015 Wu F, Torre E, Cuellar-Giraldo D, Cheng L, Yi H, Bichler EK, García PS, Yepes M. Tissue-type plasminogen activator triggers the synaptic vesicle cycle in cerebral cortical neurons. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26126868 DOI: 10.1038/jcbfm.2015.155  0.39
2014 Wu F, Catano M, Echeverry R, Torre E, Haile WB, An J, Chen C, Cheng L, Nicholson A, Tong FC, Park J, Yepes M. Urokinase-type plasminogen activator promotes dendritic spine recovery and improves neurological outcome following ischemic stroke. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14219-32. PMID 25339736 DOI: 10.1523/JNEUROSCI.5309-13.2014  0.411
2013 Wu F, Nicholson AD, Haile WB, Torre E, An J, Chen C, Lee AK, Duong DM, Dammer EB, Seyfried NT, Tong FC, Votaw JR, Yepes M. Tissue-type plasminogen activator mediates neuronal detection and adaptation to metabolic stress. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1761-9. PMID 23881246 DOI: 10.1038/Jcbfm.2013.124  0.481
2012 Wu F, Echeverry R, Wu J, An J, Haile WB, Cooper DS, Catano M, Yepes M. Tissue-type plasminogen activator protects neurons from excitotoxin-induced cell death via activation of the ERK1/2-CREB-ATF3 signaling pathway. Molecular and Cellular Neurosciences. 52: 9-19. PMID 23063501 DOI: 10.1016/j.mcn.2012.10.001  0.56
2012 Wu F, Wu J, Nicholson AD, Echeverry R, Haile WB, Catano M, An J, Lee AK, Duong D, Dammer EB, Seyfried NT, Tong FC, Votaw JR, Medcalf RL, Yepes M. Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9848-58. PMID 22815500 DOI: 10.1523/Jneurosci.1241-12.2012  0.487
2012 Echeverry R, Wu F, Haile WB, Wu J, Yepes M. The cytokine tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 have a neuroprotective effect in the central nervous system. Journal of Neuroinflammation. 9: 45. PMID 22394384 DOI: 10.1186/1742-2094-9-45  0.324
2011 Haile WB, Wu J, Echeverry R, Wu F, An J, Yepes M. Tissue-type plasminogen activator has a neuroprotective effect in the ischemic brain mediated by neuronal TNF-α. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 57-69. PMID 21792242 DOI: 10.1038/jcbfm.2011.106  0.565
2011 Chan CB, Liu X, Pradoldej S, Hao C, An J, Yepes M, Luo HR, Ye K. Phosphoinositide 3-kinase enhancer regulates neuronal dendritogenesis and survival in neocortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8083-92. PMID 21632930 DOI: 10.1523/Jneurosci.1129-11.2011  0.496
2010 Jang SW, Liu X, Yepes M, Shepherd KR, Miller GW, Liu Y, Wilson WD, Xiao G, Blanchi B, Sun YE, Ye K. A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone. Proceedings of the National Academy of Sciences of the United States of America. 107: 2687-92. PMID 20133810 DOI: 10.1073/Pnas.0913572107  0.399
2009 Jang SW, Liu X, Fu H, Rees H, Yepes M, Levey A, Ye K. Interaction of Akt-phosphorylated SRPK2 with 14-3-3 mediates cell cycle and cell death in neurons. The Journal of Biological Chemistry. 284: 24512-25. PMID 19592491 DOI: 10.1074/Jbc.M109.026237  0.369
2009 Roussel BD, Macrez R, Jullienne A, Agin V, Maubert E, Dauphinot L, Potier MC, Plawinski L, Castel H, Hommet Y, Munuera J, Montaner J, Yepes M, Ali C, Vivien D. Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact. Brain : a Journal of Neurology. 132: 2219-30. PMID 19574439 DOI: 10.1093/brain/awp162  0.306
2009 Zhang C, An J, Strickland DK, Yepes M. The low-density lipoprotein receptor-related protein 1 mediates tissue-type plasminogen activator-induced microglial activation in the ischemic brain. The American Journal of Pathology. 174: 586-94. PMID 19147818 DOI: 10.2353/Ajpath.2009.080661  0.367
2009 Yepes M, Roussel BD, Ali C, Vivien D. Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic. Trends in Neurosciences. 32: 48-55. PMID 18963068 DOI: 10.1016/j.tins.2008.09.006  0.302
2008 An J, Zhang C, Polavarapu R, Zhang X, Zhang X, Yepes M. Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein induce Akt phosphorylation in the ischemic brain. Blood. 112: 2787-94. PMID 18628488 DOI: 10.1182/blood-2008-02-141630  0.42
2008 Mannaioni G, Orr AG, Hamill CE, Yuan H, Pedone KH, McCoy KL, Berlinguer Palmini R, Junge CE, Lee CJ, Yepes M, Hepler JR, Traynelis SF. Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1. The Journal of Biological Chemistry. 283: 20600-11. PMID 18474593 DOI: 10.1074/Jbc.M803015200  0.331
2008 Polavarapu R, An J, Zhang C, Yepes M. Regulated intramembrane proteolysis of the low-density lipoprotein receptor-related protein mediates ischemic cell death. The American Journal of Pathology. 172: 1355-62. PMID 18403601 DOI: 10.2353/ajpath.2008.070975  0.343
2008 Liu Z, Jang SW, Liu X, Cheng D, Peng J, Yepes M, Li XJ, Matthews S, Watts C, Asano M, Hara-Nishimura I, Luo HR, Ye K. Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase. Molecular Cell. 29: 665-78. PMID 18374643 DOI: 10.1016/J.Molcel.2008.02.017  0.427
2007 Zhang X, Polavarapu R, She H, Mao Z, Yepes M. Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein mediate cerebral ischemia-induced nuclear factor-kappaB pathway activation. The American Journal of Pathology. 171: 1281-90. PMID 17717150 DOI: 10.2353/ajpath.2007.070472  0.352
2006 Polavarapu R, Gongora MC, Yi H, Ranganthan S, Lawrence DA, Strickland D, Yepes M. Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit. Blood. 109: 3270-8. PMID 17170123 DOI: 10.1182/Blood-2006-08-043125  0.324
2005 Yepes M, Brown SA, Moore EG, Smith EP, Lawrence DA, Winkles JA. A soluble Fn14-Fc decoy receptor reduces infarct volume in a murine model of cerebral ischemia. The American Journal of Pathology. 166: 511-20. PMID 15681834 DOI: 10.1016/S0002-9440(10)62273-0  0.359
2002 Zhang Z, Zhang L, Yepes M, Jiang Q, Li Q, Arniego P, Coleman TA, Lawrence DA, Chopp M. Adjuvant treatment with neuroserpin increases the therapeutic window for tissue-type plasminogen activator administration in a rat model of embolic stroke. Circulation. 106: 740-5. PMID 12163437 DOI: 10.1161/01.Cir.0000023942.10849.41  0.41
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