Year |
Citation |
Score |
2023 |
Miller ET, Tsodikov OV, Garneau-Tsodikova S. Structural insights into the diverse prenylating capabilities of DMATS prenyltransferases. Natural Product Reports. PMID 37929638 DOI: 10.1039/d3np00036b |
0.558 |
|
2023 |
Pang AH, Green KD, Tsodikov OV, Garneau-Tsodikova S. Discovery and development of inhibitors of acetyltransferase Eis to combat Mycobacterium tuberculosis. Methods in Enzymology. 690: 369-396. PMID 37858535 DOI: 10.1016/bs.mie.2023.06.017 |
0.648 |
|
2023 |
Thamban Chandrika N, Green KD, Spencer AC, Tsodikov OV, Garneau-Tsodikova S. Discovery and development of novel substituted monohydrazides as potent antifungal agents. Rsc Medicinal Chemistry. 14: 1351-1361. PMID 37484566 DOI: 10.1039/d3md00167a |
0.531 |
|
2023 |
Travis S, Green KD, Thamban Chandrika N, Pang AH, Frantom PA, Tsodikov OV, Garneau-Tsodikova S, Thompson MK. Identification and analysis of small molecule inhibitors of FosB from . Rsc Medicinal Chemistry. 14: 947-956. PMID 37252104 DOI: 10.1039/d3md00113j |
0.651 |
|
2023 |
Gelzinis JA, Szahaj MK, Bekendam RH, Wurl SE, Pantos MM, Verbetsky CA, Dufresne A, Shea M, Howard KC, Tsodikov OV, Garneau-Tsodikova S, Zwicker JI, Kennedy DR. Targeting thiol isomerase activity with zafirlukast to treat ovarian cancer from the bench to clinic. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 37: e22914. PMID 37043381 DOI: 10.1096/fj.202201952R |
0.487 |
|
2023 |
Green KD, Thamban Chandrika N, Vu LY, Pang AH, Tsodikov OV, Garneau-Tsodikova S. Aromatic hydrazides: A potential solution for Acinetobacter baumannii infections. European Journal of Medicinal Chemistry. 249: 115165. PMID 36739749 DOI: 10.1016/j.ejmech.2023.115165 |
0.584 |
|
2023 |
Pang AH, Green KD, Punetha A, Thamban Chandrika N, Howard KC, Garneau-Tsodikova S, Tsodikov OV. Discovery and Mechanistic Analysis of Structurally Diverse Inhibitors of Acetyltransferase Eis among FDA-Approved Drugs. Biochemistry. 62: 710-721. PMID 36657084 DOI: 10.1021/acs.biochem.2c00658 |
0.629 |
|
2022 |
Travis S, Green KD, Gilbert NC, Tsodikov OV, Garneau-Tsodikova S, Thompson MK. Inhibition of Fosfomycin Resistance Protein FosB from Gram-Positive Pathogens by Phosphonoformate. Biochemistry. PMID 36525630 DOI: 10.1021/acs.biochem.2c00566 |
0.646 |
|
2022 |
Pang AH, Tsodikov OV. A Colorimetric Assay to Identify and Characterize Bacterial Primase Inhibitors. Methods in Molecular Biology (Clifton, N.J.). 2601: 283-301. PMID 36445590 DOI: 10.1007/978-1-0716-2855-3_15 |
0.313 |
|
2022 |
Pang AH, Green KD, Chandrika NT, Garzan A, Punetha A, Holbrook SYL, Willby MJ, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity. European Journal of Medicinal Chemistry. 242: 114698. PMID 36037791 DOI: 10.1016/j.ejmech.2022.114698 |
0.663 |
|
2022 |
Green KD, Pang AH, Thamban Chandrika N, Garzan A, Baughn AD, Tsodikov OV, Garneau-Tsodikova S. Discovery and Optimization of 6-(1-Substituted pyrrole-2-yl)--triazine Containing Compounds as Antibacterial Agents. Acs Infectious Diseases. 8: 757-767. PMID 35239306 DOI: 10.1021/acsinfecdis.1c00450 |
0.59 |
|
2021 |
Punetha A, Green KD, Garzan A, Thamban Chandrika N, Willby MJ, Pang AH, Hou C, Holbrook SYL, Krieger K, Posey JE, Parish T, Tsodikov OV, Garneau-Tsodikova S. Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from to overcome kanamycin resistance. Rsc Medicinal Chemistry. 12: 1894-1909. PMID 34825186 DOI: 10.1039/d1md00239b |
0.659 |
|
2021 |
Green KD, Punetha A, Chandrika NT, Hou C, Garneau-Tsodikova S, Tsodikov OV. Development of single-stranded DNA bisintercalating inhibitors of primase DnaG as antibiotics. Chemmedchem. PMID 33711198 DOI: 10.1002/cmdc.202100001 |
0.603 |
|
2020 |
Mori S, Garneau-Tsodikova S, Tsodikov OV. Unimodular Methylation by Adenylation-Thiolation Domains Containing an Embedded Methyltransferase. Journal of Molecular Biology. PMID 32920052 DOI: 10.1016/J.Jmb.2020.09.004 |
0.495 |
|
2020 |
Punetha A, Ngo HX, Holbrook SYL, Green KD, Willby MJ, Bonnett SA, Krieger K, Dennis EK, Posey JE, Parish T, Tsodikov OV, Garneau-Tsodikova S. Structure-Guided Optimization of Inhibitors of Acetyltransferase Eis from . Acs Chemical Biology. PMID 32421305 DOI: 10.1021/Acschembio.0C00184 |
0.646 |
|
2019 |
Thamban Chandrika N, Fosso MY, Tsodikov OV, LeVine Iii H, Garneau-Tsodikova S. Combining Chalcones with Donepezil to Inhibit Both Cholinesterases and Aβ Fibril Assembly. Molecules (Basel, Switzerland). 25. PMID 31878304 DOI: 10.3390/Molecules25010077 |
0.544 |
|
2019 |
Green KD, Punetha A, Hou C, Garneau-Tsodikova S, Tsodikov OV. Probing the Robustness of Inhibitors of Tuberculosis Aminoglycoside Resistance Enzyme Eis by Mutagenesis. Acs Infectious Diseases. PMID 31433614 DOI: 10.1021/Acsinfecdis.9B00228 |
0.659 |
|
2019 |
Mori S, Pang AH, Chandrika NT, Garneau-Tsodikova S, Tsodikov OV. Publisher Correction: Unusual substrate and halide versatility of phenolic halogenase PltM. Nature Communications. 10: 2053. PMID 31040284 DOI: 10.1038/S41467-019-09731-8 |
0.444 |
|
2019 |
Mori S, Pang AH, Thamban Chandrika N, Garneau-Tsodikova S, Tsodikov OV. Unusual substrate and halide versatility of phenolic halogenase PltM. Nature Communications. 10: 1255. PMID 30890712 DOI: 10.1038/s41467-019-09215-9 |
0.557 |
|
2019 |
Hayden RC, Hou C, Mitra P, Mandal A, Rohr J, Thorson J, Tsodikov O, Leggas M. Abstract 2954: Mithramycin analogues disrupt ETS transcription factor DNA binding Cancer Research. 79: 2954-2954. DOI: 10.1158/1538-7445.Sabcs18-2954 |
0.326 |
|
2018 |
Holbrook SYL, Gentry MS, Tsodikov OV, Garneau-Tsodikova S. Nucleoside triphosphate cosubstrates control the substrate profile and efficiency of aminoglycoside 3'--phosphotransferase type IIa. Medchemcomm. 9: 1332-1339. PMID 30151088 DOI: 10.1039/C8Md00234G |
0.549 |
|
2018 |
Ngo HX, Green KD, Gajadeera CS, Willby MJ, Holbrook SYL, Hou C, Garzan A, Mayhoub AS, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Potent 1,2,4-Triazino[5,6 b]indole-3-thioether Inhibitors of the Kanamycin Resistance Enzyme Eis from Mycobacterium tuberculosis. Acs Infectious Diseases. PMID 29601176 DOI: 10.1021/Acsinfecdis.8B00074 |
0.659 |
|
2018 |
Mori S, Pang AH, Lundy TA, Garzan A, Tsodikov OV, Garneau-Tsodikova S. Structural basis for backbone N-methylation by an interrupted adenylation domain. Nature Chemical Biology. PMID 29556104 DOI: 10.1038/S41589-018-0014-7 |
0.552 |
|
2018 |
Green KD, Biswas T, Pang AH, Willby MJ, Reed MS, Stuchlik O, Pohl J, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Acetylation by Eis and Deacetylation by Rv1151c of Mycobacterium tuberculosis HupB: Biochemical and Structural Insight. Biochemistry. PMID 29345920 DOI: 10.1021/Acs.Biochem.7B01089 |
0.549 |
|
2017 |
Thamban Chandrika N, Shrestha SK, Ngo HX, Tsodikov OV, Howard KC, Garneau-Tsodikova S. Alkylated Piperazines and Piperazine-Azole Hybrids as Antifungal Agents. Journal of Medicinal Chemistry. PMID 29256601 DOI: 10.1021/Acs.Jmedchem.7B01138 |
0.59 |
|
2017 |
Mori S, Garzan A, Tsodikov OV, Garneau-Tsodikova S. Deciphering Nature's Intricate Way of N,S-Dimethylating l-Cysteine: Sequential Action of Two Bifunctional Adenylation Domains. Biochemistry. PMID 29112395 DOI: 10.1021/Acs.Biochem.7B00980 |
0.513 |
|
2017 |
Garzan A, Willby MJ, Ngo HX, Gajadeera CS, Green KD, Holbrook SY, Hou C, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Combating Eis-mediated kanamycin resistance of M. tuber-culosis by novel pyrrolo[1,5-a]pyrazine-based Eis inhibitors. Acs Infectious Diseases. PMID 28192916 DOI: 10.1021/Acsinfecdis.6B00193 |
0.662 |
|
2017 |
Pang AH, Garneau-Tsodikova S, Tsodikov OV. In Vitro Assays to Identify Antibiotics Targeting DNA Metabolism. Methods in Molecular Biology (Clifton, N.J.). 1520: 175-200. PMID 27873253 DOI: 10.1007/978-1-4939-6634-9_11 |
0.519 |
|
2016 |
Garzan A, Willby MJ, Green KD, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Discovery and Optimization of Two Eis Inhibitor Families as Kanamycin Adjuvants against Drug-Resistant M. tuberculosis. Acs Medicinal Chemistry Letters. 7: 1219-1221. PMID 27994767 DOI: 10.1021/Acsmedchemlett.6B00261 |
0.629 |
|
2016 |
Garzan A, Willby MJ, Green KD, Gajadeera CS, Hou C, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 59: 10619-10628. PMID 27933949 DOI: 10.1021/Acs.Jmedchem.6B01161 |
0.644 |
|
2016 |
Pang AH, Garzan A, Larsen MJ, McQuade TJ, Garneau-Tsodikova S, Tsodikov OV. Discovery of allosteric and selective inhibitors of inorganic pyrophosphatase from Mycobacterium tuberculosis. Acs Chemical Biology. PMID 27622287 DOI: 10.1021/Acschembio.6B00510 |
0.639 |
|
2016 |
Willby MJ, Green KD, Gajadeera CS, Hou C, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Potent inhibitors of acetyltransferase Eis overcome kanamycin re-sistance in Mycobacterium tuberculosis. Acs Chemical Biology. PMID 27010218 DOI: 10.1021/Acschembio.6B00110 |
0.656 |
|
2015 |
Pang AH, Garneau-Tsodikova S, Tsodikov OV. Crystal structure of halogenase PltA from the pyoluteorin biosynthetic pathway. Journal of Structural Biology. PMID 26416533 DOI: 10.1016/J.Jsb.2015.09.013 |
0.562 |
|
2015 |
Pratt AC, Dewage SW, Pang AH, Biswas T, Barnard-Britson S, Cisneros GA, Tsodikov OV. Structural and computational dissection of the catalytic mechanism of the inorganic pyrophosphatase from Mycobacterium tuberculosis. Journal of Structural Biology. 192: 76-87. PMID 26296329 DOI: 10.1016/J.Jsb.2015.08.010 |
0.32 |
|
2015 |
Fosso MY, LeVine H, Green KD, Tsodikov OV, Garneau-Tsodikova S. Effects of structural modifications on the metal binding, anti-amyloid activity, and cholinesterase inhibitory activity of chalcones. Organic & Biomolecular Chemistry. 13: 9418-26. PMID 26248214 DOI: 10.1039/C5Ob01478F |
0.528 |
|
2015 |
Tsodikov OV, Hou C, Walsh CT, Garneau-Tsodikova S. Crystal structure of O-methyltransferase CalO6 from the calicheamicin biosynthetic pathway: a case of challenging structure determination at low resolution. Bmc Structural Biology. 15: 13. PMID 26170207 DOI: 10.1186/S12900-015-0040-6 |
0.562 |
|
2015 |
Green KD, Biswas T, Chang C, Wu R, Chen W, Janes BK, Chalupska D, Gornicki P, Hanna PC, Tsodikov OV, Joachimiak A, Garneau-Tsodikova S. Biochemical and Structural Analysis of an Eis Family Aminoglycoside Acetyltransferase from Bacillus anthracis. Biochemistry. 54: 3197-206. PMID 25928210 DOI: 10.1021/Acs.Biochem.5B00244 |
0.612 |
|
2015 |
Gajadeera C, Willby MJ, Green KD, Shaul P, Fridman M, Garneau-Tsodikova S, Posey JE, Tsodikov OV. Antimycobacterial activity of DNA intercalator inhibitors of Mycobacterium tuberculosis primase DnaG. The Journal of Antibiotics. 68: 153-7. PMID 25248725 DOI: 10.1038/Ja.2014.131 |
0.64 |
|
2015 |
Tsodikov OV, Hou C, Walsh CT, Garneau-Tsodikova S. Crystal structure of O-methyltransferase CalO6 from the calicheamicin biosynthetic pathway: A case of challenging structure determination at low resolution Bmc Structural Biology. 15. DOI: 10.1186/s12900-015-0040-6 |
0.509 |
|
2015 |
Fosso MY, LeVine H, Green KD, Tsodikov OV, Garneau-Tsodikova S. Effects of structural modifications on the metal binding, anti-amyloid activity, and cholinesterase inhibitory activity of chalcones Organic and Biomolecular Chemistry. 13: 9418-9426. DOI: 10.1039/c5ob01478f |
0.526 |
|
2014 |
Tsodikov OV, Green KD, Garneau-Tsodikova S. A random sequential mechanism of aminoglycoside acetylation by Mycobacterium tuberculosis Eis protein. Plos One. 9: e92370. PMID 24699000 DOI: 10.1371/Journal.Pone.0092370 |
0.619 |
|
2013 |
Houghton JL, Biswas T, Chen W, Tsodikov OV, Garneau-Tsodikova S. Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase Eis. Chembiochem : a European Journal of Chemical Biology. 14: 2127-35. PMID 24106131 DOI: 10.1002/Cbic.201300359 |
0.64 |
|
2013 |
Biswas T, Green KD, Garneau-Tsodikova S, Tsodikov OV. Discovery of inhibitors of Bacillus anthracis primase DnaG. Biochemistry. 52: 6905-10. PMID 24004110 DOI: 10.1021/Bi4011286 |
0.602 |
|
2013 |
Larrouy-Maumus G, Biswas T, Hunt DM, Kelly G, Tsodikov OV, de Carvalho LP. Discovery of a glycerol 3-phosphate phosphatase reveals glycerophospholipid polar head recycling in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 110: 11320-5. PMID 23801751 DOI: 10.1073/Pnas.1221597110 |
0.305 |
|
2013 |
Houghton JL, Biswas T, Chen W, Tsodikov OV, Garneau-Tsodikova S. Cover Picture: Chemical and Structural Insights into the Regioversatility of the Aminoglycoside Acetyltransferase Eis (ChemBioChem 16/2013) Chembiochem. 14: 2061-2061. DOI: 10.1002/cbic.201390058 |
0.521 |
|
2012 |
Chen W, Green KD, Tsodikov OV, Garneau-Tsodikova S. Aminoglycoside multiacetylating activity of the enhanced intracellular survival protein from Mycobacterium smegmatis and its inhibition. Biochemistry. 51: 4959-67. PMID 22646013 DOI: 10.1021/Bi3004473 |
0.606 |
|
2012 |
Biswas T, Houghton JL, Garneau-Tsodikova S, Tsodikov OV. The structural basis for substrate versatility of chloramphenicol acetyltransferase CATI. Protein Science : a Publication of the Protein Society. 21: 520-30. PMID 22294317 DOI: 10.1002/Pro.2036 |
0.592 |
|
2011 |
Chen W, Biswas T, Porter VR, Tsodikov OV, Garneau-Tsodikova S. Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB. Proceedings of the National Academy of Sciences of the United States of America. 108: 9804-8. PMID 21628583 DOI: 10.1073/Pnas.1105379108 |
0.61 |
|
2010 |
Biswas T, Zolova OE, Lombó F, de la Calle F, Salas JA, Tsodikov OV, Garneau-Tsodikova S. A new scaffold of an old protein fold ensures binding to the bisintercalator thiocoraline. Journal of Molecular Biology. 397: 495-507. PMID 20122935 DOI: 10.1016/J.Jmb.2010.01.053 |
0.562 |
|
2009 |
Biswas T, Yi L, Aggarwal P, Wu J, Rubin JR, Stuckey JA, Woodard RW, Tsodikov OV. The tail of KdsC: conformational changes control the activity of a haloacid dehalogenase superfamily phosphatase. The Journal of Biological Chemistry. 284: 30594-603. PMID 19726684 DOI: 10.1074/Jbc.M109.012278 |
0.314 |
|
2009 |
Garneau-Tsodikova S, Shkel IA, Tsodikov OV. Exact and user-friendly kinetic analysis of the two-step rapid equilibrium Michaelis-Menten mechanism. Analytical Biochemistry. 387: 276-9. PMID 19344659 DOI: 10.1016/J.Ab.2009.01.023 |
0.491 |
|
2009 |
McQuade TJ, Shallop AD, Sheoran A, Delproposto JE, Tsodikov OV, Garneau-Tsodikova S. A nonradioactive high-throughput assay for screening and characterization of adenylation domains for nonribosomal peptide combinatorial biosynthesis. Analytical Biochemistry. 386: 244-50. PMID 19135023 DOI: 10.1016/J.Ab.2008.12.014 |
0.535 |
|
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