Christopher T. Lemke, Ph.D.

Affiliations: 
2002 University of Toronto, Toronto, ON, Canada 
Area:
Biochemistry, Pathology
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"Christopher Lemke"
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P. Lynne Howell grad student 2002 University of Toronto
 (X-ray crystallographic studies of argininosuccinate synthetase.)
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Publications

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Fong DH, Lemke CT, Hwang J, et al. (2010) Structure of the antibiotic resistance factor spectinomycin phosphotransferase from Legionella pneumophila. The Journal of Biological Chemistry. 285: 9545-55
Smith GD, Lemke CT, Howell PL. (2007) Substructure determination in multiwavelength anomalous diffraction, single anomalous diffraction, and single isomorphous replacement with anomalous scattering data using Shake-and-Bake. Methods in Molecular Biology (Clifton, N.J.). 364: 183-96
Lemke CT, Smith GD, Howell PL. (2002) S-SAD, Se-SAD and S/Se-SIRAS using Cu Kalpha radiation: why wait for synchrotron time? Acta Crystallographica. Section D, Biological Crystallography. 58: 2096-101
Lemke CT, Howell PL. (2002) Substrate induced conformational changes in argininosuccinate synthetase. The Journal of Biological Chemistry. 277: 13074-81
Lemke CT, Howell PL. (2001) The 1.6 A crystal structure of E. coli argininosuccinate synthetase suggests a conformational change during catalysis. Structure (London, England : 1993). 9: 1153-64
Lemke C, Yeung M, Howell PL. (1999) Expression, purification, crystallization and preliminary X-ray analysis of Escherichia coli argininosuccinate synthetase. Acta Crystallographica. Section D, Biological Crystallography. 55: 2028-30
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