| Year |
Citation |
Score |
| 2020 |
Hong B, Luo T, Lei X. Late-Stage Diversification of Natural Products. Acs Central Science. 6: 622-635. PMID 32490181 DOI: 10.1021/Acscentsci.9B00916 |
0.321 |
|
| 2020 |
Gao L, Su C, Du X, Wang R, Chen S, Zhou Y, Liu C, Liu X, Tian R, Zhang L, Xie K, Chen S, Guo Q, Guo L, Hano Y, ... ... Lei X, et al. FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis. Nature Chemistry. PMID 32451436 DOI: 10.1038/S41557-020-0467-7 |
0.354 |
|
| 2020 |
Bai Y, Lam HC, Lei X. Dissecting Programmed Cell Death with Small Molecules. Accounts of Chemical Research. PMID 32297735 DOI: 10.1021/Acs.Accounts.9B00600 |
0.39 |
|
| 2020 |
Wang J, Hong B, Hu D, Kadonaga Y, Tang R, Lei X. Protecting-group-free syntheses of ent-kaurane diterpenoids: [3+2+1] cycloaddition/cycloalkenylation approach. Journal of the American Chemical Society. PMID 31968171 DOI: 10.1021/Jacs.9B13722 |
0.302 |
|
| 2020 |
Meesakul P, Jaidee W, Richardson C, Andersen RJ, Patrick BO, Willis AC, Muanprasat C, Wang J, Lei X, Hadsadee S, Jungsuttiwong S, Pyne SG, Laphookhieo S. Styryllactones from Goniothalamus tamirensis. Phytochemistry. 171: 112248. PMID 31918304 DOI: 10.1016/J.Phytochem.2019.112248 |
0.312 |
|
| 2019 |
Lei X, Yue Z, Lam H, Chen K, Siridechakorn I, Liu Y, Pudhom K. Biomimetic synthesis of rhytidenone A and elucidation of mode of action of the cytotoxic rhytidenone F. Angewandte Chemie (International Ed. in English). PMID 31868281 DOI: 10.1002/Anie.201914257 |
0.302 |
|
| 2019 |
Zhang J, Zhao T, Yang R, Siridechakorn I, Wang S, Guo Q, Bai Y, Shen HC, Lei X. synthesis, structural assignment and biological evaluation of pseudopaline, a metallophore produced by . Chemical Science. 10: 6635-6641. PMID 31367316 DOI: 10.1039/C9Sc01405E |
0.379 |
|
| 2019 |
Shi Y, Xu Z, Tan R, Lei X. Divergent Total Synthesis of Chaetoglines C to F. The Journal of Organic Chemistry. PMID 31185713 DOI: 10.1021/Acs.Joc.9B01076 |
0.32 |
|
| 2019 |
Lei X, Wu J, Kadonaga Y, Hong B, Wang J. 13-step Enantioselective Total Synthesis of (+)-Jungermatrobrunin A. Angewandte Chemie (International Ed. in English). PMID 31056826 DOI: 10.1002/Anie.201903682 |
0.313 |
|
| 2019 |
Hong B, Liu W, Wang J, Wu J, Kadonaga Y, Cai P, Lou H, Yu Z, Li H, Lei X. Photoinduced Skeletal Rearrangements Reveal Radical-Mediated Synthesis of Terpenoids Chem. 5: 1671-1681. DOI: 10.1016/J.Chempr.2019.04.023 |
0.374 |
|
| 2018 |
Wang X, Du C, Hong B, Lei X. Total synthesis of (±)-antroquinonol. Organic & Biomolecular Chemistry. PMID 30418462 DOI: 10.1039/C8Ob02494D |
0.328 |
|
| 2018 |
Ozaki T, Shinde SS, Gao L, Okuizumi R, Liu C, Ogasawara Y, Lei X, Dairi T, Minami A, Oikawa H. Enzymatic formation of a skipped methyl-substituted octaprenyl side chain of longestin (KS-505a): Involvement of homo-IPP as a common extender unit. Angewandte Chemie (International Ed. in English). PMID 29603559 DOI: 10.1002/Anie.201802116 |
0.303 |
|
| 2017 |
Li H, Lei X. Fawcettimine-Type Lycopodium Alkaloids as a Driving Force for Discoveries in Organic Synthesis. Chemical Record (New York, N.Y.). PMID 29251805 DOI: 10.1002/Tcr.201700047 |
0.306 |
|
| 2017 |
Narita K, Sato H, Minami A, Kudo K, Gao L, Liu C, Ozaki T, Kodama M, Lei X, Taniguchi T, Monde K, Yamazaki M, Uchiyama M, Oikawa H. Focused Genome Mining of Structurally Related Sesterterpenes: Enzymatic Formation of Enantiomeric and Diastereomeric Products. Organic Letters. 19: 6696-6699. PMID 29185768 DOI: 10.1021/Acs.Orglett.7B03418 |
0.332 |
|
| 2017 |
Lei X, Hong B, Hu D, Wu J, Zhang J, Li H. Divergent Total Syntheses of (-)-Huperzine Q, (+)-Lycopladine B, (+)-Lycopladine C and (-)-4-epi-Lycopladine D. Chemistry, An Asian Journal. PMID 28440575 DOI: 10.1002/Asia.201700364 |
0.329 |
|
| 2016 |
Ren Y, Su Y, Sun L, He S, Meng L, Liao D, Liu X, Ma Y, Liu C, Li S, Ruan H, Lei X, Wang X, Zhang Z. Discovery of a highly potent, selective, and metabolically stable inhibitor of receptor-interacting protein 1 (RIP1) for the treatment of systemic inflammatory response syndrome. Journal of Medicinal Chemistry. PMID 27992216 DOI: 10.1021/Acs.Jmedchem.6B01196 |
0.318 |
|
| 2016 |
Li D, Li C, Li L, Chen S, Wang L, Li Q, Wang X, Lei X, Shen Z. Natural Product Kongensin A is a Non-Canonical HSP90 Inhibitor that Blocks RIP3-dependent Necroptosis. Cell Chemical Biology. 23: 257-266. PMID 27028885 DOI: 10.1016/J.Chembiol.2015.08.018 |
0.34 |
|
| 2016 |
Yang S, Liao D, Tian X, Lei X. Access to the 2H-Tetrahydro-4,6-dioxo-1,2-oxazine Ring System from Nitrone via a Tandem Nucleophilic Addition and Transesterification Reaction. Organic Letters. 18: 376-379. PMID 26849452 DOI: 10.1021/Acs.Orglett.5B03374 |
0.343 |
|
| 2016 |
Liu W, Li H, Cai PJ, Wang Z, Yu ZX, Lei X. Scalable Total Synthesis of rac-Jungermannenones B and C. Angewandte Chemie (International Ed. in English). PMID 26823176 DOI: 10.1002/Anie.201511659 |
0.361 |
|
| 2016 |
Dong T, Liu W, Shen Z, Li L, Chen S, Lei X. Pterisolic Acid B is a Nrf2 Activator by Targeting C171 within Keap1-BTB Domain. Scientific Reports. 6: 19231. PMID 26757824 DOI: 10.1038/Srep19231 |
0.363 |
|
| 2016 |
Gao L, Han J, Lei X. Enantioselective Total Syntheses of Kuwanon X, Kuwanon Y, and Kuwanol A. Organic Letters. PMID 26756182 DOI: 10.1021/Acs.Orglett.5B03285 |
0.324 |
|
| 2016 |
Lei XG, Zhu JH, Cheng WH, Bao Y, Ho YS, Reddi AR, Holmgren A, Arnér ES. Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications. Physiological Reviews. 96: 307-64. PMID 26681794 DOI: 10.1152/Physrev.00010.2014 |
0.39 |
|
| 2016 |
Ma K, Liao D, Yang S, Li X, Lei X. Studies towards the synthesis of the functionalized C3–C14 decalin framework of alchivemycin A Organic Chemistry Frontiers. 3: 251-258. DOI: 10.1039/C5Qo00343A |
0.358 |
|
| 2016 |
Hong B, Dong T, Lei X. Recent advances in target identification by natural product based chemical probes Science China Chemistry. 59: 1088-1092. DOI: 10.1007/S11426-016-0063-5 |
0.304 |
|
| 2015 |
Li X, Han J, Jones AX, Lei X. Chiral Boron Complex-Promoted Asymmetric Diels-Alder Cycloaddition and Its Application in Natural Product Synthesis. The Journal of Organic Chemistry. PMID 26693852 DOI: 10.1021/Acs.Joc.5B02248 |
0.375 |
|
| 2015 |
Abazov VM, Abbott B, Acharya BS, Adams M, Adams T, Agnew JP, Alexeev GD, Alkhazov G, Alton A, Askew A, Atkins S, Augsten K, Avila C, Badaud F, Bagby L, ... ... Lei X, et al. Inclusive Production of the X(4140) State in pp[over ¯] Collisions at D0. Physical Review Letters. 115: 232001. PMID 26684112 DOI: 10.1103/Physrevlett.115.232001 |
0.382 |
|
| 2015 |
Liao D, Yang S, Wang J, Zhang J, Hong B, Wu F, Lei X. Total Synthesis and Structural Reassignment of Aspergillomarasmine A. Angewandte Chemie (International Ed. in English). PMID 26592805 DOI: 10.1002/Anie.201509960 |
0.311 |
|
| 2015 |
Abazov VM, Abbott B, Acharya BS, Adams M, Adams T, Agnew JP, Alexeev GD, Alkhazov G, Alton A, Askew A, Atkins S, Augsten K, Avila C, Badaud F, Bagby L, ... ... Lei X, et al. Search for Violation of CPT and Lorentz Invariance in Bs(0) Meson Oscillations. Physical Review Letters. 115: 161601. PMID 26550864 DOI: 10.1103/Physrevlett.115.161601 |
0.366 |
|
| 2015 |
Aaltonen T, Abazov VM, Abbott B, Acharya BS, Adams M, Adams T, Agnew JP, Alexeev GD, Alkhazov G, Alton A, Amerio S, Amidei D, Anastassov A, Annovi A, Antos J, ... ... Lei X, et al. Tevatron Combination of Single-Top-Quark Cross Sections and Determination of the Magnitude of the Cabibbo-Kobayashi-Maskawa Matrix Element V_{tb}. Physical Review Letters. 115: 152003. PMID 26550718 DOI: 10.1103/Physrevlett.115.152003 |
0.357 |
|
| 2015 |
Aad G, Abbott B, Abdallah J, Abdinov O, Aben R, Abolins M, AbouZeid OS, Abramowicz H, Abreu H, Abreu R, Abulaiti Y, Acharya BS, Adamczyk L, Adams DL, Adelman J, ... Lei X, et al. ATLAS Run 1 searches for direct pair production of third-generation squarks at the Large Hadron Collider. The European Physical Journal. C, Particles and Fields. 75: 510. PMID 26549981 DOI: 10.1140/Epjc/S10052-015-3726-9 |
0.388 |
|
| 2015 |
Aad G, Abbott B, Abdallah J, Abdinov O, Aben R, Abolins M, AbouZeid OS, Abramowicz H, Abreu H, Abreu R, Abulaiti Y, Acharya BS, Adamczyk L, Adams DL, ... Lei X, et al. Search for metastable heavy charged particles with large ionisation energy loss in pp collisions at [Formula: see text] TeV using the ATLAS experiment. The European Physical Journal. C, Particles and Fields. 75: 407. PMID 26543401 DOI: 10.1140/Epjc/S10052-015-3609-0 |
0.357 |
|
| 2015 |
Li C, Jones AX, Lei X. Synthesis and mode of action of oligomeric sesquiterpene lactones. Natural Product Reports. PMID 26510522 DOI: 10.1039/C5Np00089K |
0.386 |
|
| 2015 |
Hong B, Li C, Wang Z, Chen J, Li H, Lei X. Enantioselective Total Synthesis of (-)-Incarviatone A. Journal of the American Chemical Society. 137: 11946-9. PMID 26371964 DOI: 10.1021/Jacs.5B08551 |
0.364 |
|
| 2015 |
Qin XY, Chen BY, Fu JJ, Shan L, Lei XG, Zhang WD. Synthesis, cytotoxicity and inhibition of NO production of ivangustin enantiomer analogues. European Journal of Medicinal Chemistry. 102: 256-265. PMID 26280922 DOI: 10.1016/J.Ejmech.2015.07.051 |
0.337 |
|
| 2015 |
Dong T, Li C, Wang X, Dian L, Zhang X, Li L, Chen S, Cao R, Li L, Huang N, He S, Lei X. Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine. Nature Communications. 6: 6522. PMID 25813672 DOI: 10.1038/Ncomms7522 |
0.731 |
|
| 2015 |
Liu W, Li X, Chen J, Li T, Dong M, Lei X. Site-selective and metal-free aliphatic C-H oxidation enabled synthesis of [5,24,25-D3]-(25S)-Δ(7)-dafachronic acid. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 5345-9. PMID 25704922 DOI: 10.1002/Chem.201500324 |
0.322 |
|
| 2015 |
Hong B, Li H, Wu J, Zhang J, Lei X. Total syntheses of (-)-huperzine Q and (+)-lycopladines B and C. Angewandte Chemie (International Ed. in English). 54: 1011-5. PMID 25358669 DOI: 10.1002/Anie.201409503 |
0.369 |
|
| 2015 |
Han J, Jones AX, Lei X. Recent Advances in the Total Synthesis of Prenylflavonoid and Related Diels–Alder Natural Products Synthesis. 47: 1519-1533. DOI: 10.1055/S-0034-1378696 |
0.348 |
|
| 2014 |
Zhang J, Chen J, Zhang X, Lei X. Total syntheses of menisporphine and daurioxoisoporphine C enabled by photoredox-catalyzed direct C-H arylation of isoquinoline with aryldiazonium salt. The Journal of Organic Chemistry. 79: 10682-8. PMID 25313860 DOI: 10.1021/Jo5020432 |
0.365 |
|
| 2014 |
Li C, Dong T, Li Q, Lei X. Probing the anticancer mechanism of (-)-ainsliatrimer A through diverted total synthesis and bioorthogonal ligation. Angewandte Chemie (International Ed. in English). 53: 12111-5. PMID 25223829 DOI: 10.1002/Anie.201407225 |
0.369 |
|
| 2014 |
Zhang J, Wu J, Hong B, Ai W, Wang X, Li H, Lei X. Diversity-oriented synthesis of Lycopodium alkaloids inspired by the hidden functional group pairing pattern. Nature Communications. 5: 4614. PMID 25082077 DOI: 10.1038/Ncomms5614 |
0.351 |
|
| 2014 |
Han J, Li X, Guan Y, Zhao W, Wulff WD, Lei X. Enantioselective biomimetic total syntheses of kuwanons I and J and brosimones A and B. Angewandte Chemie (International Ed. in English). 53: 9257-61. PMID 25044511 DOI: 10.1002/Anie.201404499 |
0.384 |
|
| 2014 |
Li C, Lei X. Strategies toward the biomimetic syntheses of oligomeric sesquiterpenoids. The Journal of Organic Chemistry. 79: 3289-95. PMID 24620778 DOI: 10.1021/Jo5002092 |
0.345 |
|
| 2014 |
Liao D, Sun L, Liu W, He S, Wang X, Lei X. Necrosulfonamide inhibits necroptosis by selectively targeting the mixed lineage kinase domain-like protein Medchemcomm. 5: 333-337. DOI: 10.1039/C3Md00278K |
0.306 |
|
| 2013 |
Wang G, Wang X, Yu H, Wei S, Williams N, Holmes DL, Halfmann R, Naidoo J, Wang L, Li L, Chen S, Harran P, Lei X. Small-molecule activation of the TRAIL receptor DR5 in human cancer cells Nature Chemical Biology. 9: 84-89. PMID 23292651 DOI: 10.1038/Nchembio.1153 |
0.313 |
|
| 2013 |
Li H, Wang X, Hong B, Lei X. Collective synthesis of Lycopodium alkaloids and tautomer locking strategy for the total synthesis of (-)-lycojapodine A. The Journal of Organic Chemistry. 78: 800-21. PMID 22973823 DOI: 10.1021/Jo3017555 |
0.373 |
|
| 2013 |
Wang X, Li H, Lei X. Challenges and Strategies to the Total Syntheses of Fawcettimine-Type and Serratinine-Type Lycopodium Alkaloids Synlett. 24: 1032-1043. DOI: 10.1055/S-0032-1316912 |
0.311 |
|
| 2013 |
Li C, Dong T, Dian L, Zhang W, Lei X. Biomimetic syntheses and structural elucidation of the apoptosis-inducing sesquiterpenoid trimers: (−)-ainsliatrimers A and B Chemical Science. 4: 1163. DOI: 10.1039/C2Sc22023G |
0.742 |
|
| 2013 |
Huang J, Lei X. A nature-inspired concise synthesis of (+)-ent-chromazonarol Science China-Chemistry. 56: 349-353. DOI: 10.1007/S11426-012-4826-0 |
0.37 |
|
| 2013 |
Li C, Li X, Wang X, Lei X. Diversity-oriented synthesis of bicyclic ring systems via a conjugate addition/aldol/RCM process Science China-Chemistry. 56: 337-341. DOI: 10.1007/S11426-012-4805-5 |
0.362 |
|
| 2012 |
Li C, Dian L, Zhang W, Lei X. Biomimetic syntheses of (-)-gochnatiolides A-C and (-)-ainsliadimer B. Journal of the American Chemical Society. 134: 12414-7. PMID 22799742 DOI: 10.1021/Ja305464S |
0.739 |
|
| 2012 |
Lei X, Li H. Selective alkene metathesis in the total synthesis of complex natural product. Topics in Current Chemistry. 327: 163-96. PMID 22527405 DOI: 10.1007/128_2012_318 |
0.346 |
|
| 2012 |
Li H, Wang X, Lei X. Total syntheses of Lycopodium alkaloids (+)-fawcettimine, (+)-fawcettidine, and (-)-8-deoxyserratinine. Angewandte Chemie (International Ed. in English). 51: 491-5. PMID 22109940 DOI: 10.1002/Anie.201106753 |
0.317 |
|
| 2012 |
Liao D, Li H, Lei X. Efficient generation of ortho-quinone methide: application to the biomimetic syntheses of (±)-schefflone and tocopherol trimers. Organic Letters. 14: 18-21. PMID 22047096 DOI: 10.1021/Ol202641Y |
0.334 |
|
| 2011 |
Chou TC, Dong H, Zhang X, Lei X, Hartung J, Zhang Y, Lee JH, Wilson RM, Danishefsky SJ. Multifaceted cytoprotection by synthetic polyacetylenes inspired by the ginseng-derived natural product, panaxytriol. Proceedings of the National Academy of Sciences of the United States of America. 108: 14336-41. PMID 21844359 DOI: 10.1073/Pnas.1111332108 |
0.307 |
|
| 2011 |
Li C, Tu S, Wen S, Li S, Chang J, Shao F, Lei X. Total synthesis of the G2/M DNA damage checkpoint inhibitor psilostachyin C. The Journal of Organic Chemistry. 76: 3566-70. PMID 21417227 DOI: 10.1021/Jo2001275 |
0.321 |
|
| 2010 |
Gong YN, Wang X, Wang J, Yang Z, Li S, Yang J, Liu L, Lei X, Shao F. Chemical probing reveals insights into the signaling mechanism of inflammasome activation. Cell Research. 20: 1289-305. PMID 20856264 DOI: 10.1038/Cr.2010.135 |
0.328 |
|
| 2010 |
Li C, Yu X, Lei X. A biomimetic total synthesis of (+)-ainsliadimer A. Organic Letters. 12: 4284-7. PMID 20812751 DOI: 10.1021/Ol101705J |
0.33 |
|
| 2008 |
Lei X, Danishefsky SJ. Efficient Synthesis of a Novel Resorcyclide as Anticancer Agent Based on Hsp90 Inhibition. Advanced Synthesis & Catalysis. 350: 1677-1681. PMID 21442009 DOI: 10.1002/Adsc.200800187 |
0.332 |
|
| 2008 |
Lei X, Dai M, Hua Z, Danishefsky SJ. Biomimetic total synthesis of tricycloillicinone and mechanistic studies toward the rearrangement of prenyl phenyl ethers. Tetrahedron Letters. 49: 6383-6385. PMID 19890380 DOI: 10.1016/J.Tetlet.2008.07.184 |
0.342 |
|
| 2007 |
Peng LF, Kim SS, Matchacheep S, Lei X, Su S, Lin W, Runguphan W, Choe WH, Sakamoto N, Ikeda M, Kato N, Beeler AB, Porco JA, Schreiber SL, Chung RT. Identification of novel epoxide inhibitors of hepatitis C virus replication using a high-throughput screen. Antimicrobial Agents and Chemotherapy. 51: 3756-9. PMID 17682098 DOI: 10.1128/Aac.00233-07 |
0.66 |
|
| 2006 |
Lei X, Porco JA. Total synthesis of the diazobenzofluorene antibiotic (-)-kinamycin C1. Journal of the American Chemical Society. 128: 14790-1. PMID 17105273 DOI: 10.1021/Ja066621V |
0.561 |
|
| 2006 |
Porco JA, Su S, Lei X, Bardhan S, Rychnovsky SD. Total synthesis and structure assignment of (+)-hexacyclinol. Angewandte Chemie (International Ed. in English). 45: 5790-2. PMID 16871643 DOI: 10.1002/Anie.200602854 |
0.713 |
|
| 2005 |
Lei X, Zaarur N, Sherman MY, Porco JA. Stereocontrolled synthesis of a complex library via elaboration of angular epoxyquinol scaffolds. The Journal of Organic Chemistry. 70: 6474-83. PMID 16050712 DOI: 10.1021/Jo050956Y |
0.57 |
|
| 2005 |
Su S, Acquilano DE, Arumugasamy J, Beeler AB, Eastwood EL, Giguere JR, Lan P, Lei X, Min GK, Yeager AR, Zhou Y, Panek JS, Snyder JK, Schaus SE, Porco JA. Convergent synthesis of a complex oxime library using chemical domain shuffling. Organic Letters. 7: 2751-4. PMID 15957938 DOI: 10.1021/Ol051023R |
0.643 |
|
| 2004 |
Lei X, Porco JA. Synthesis of a polymer-supported anthracene and its application as a dienophile scavenger. Organic Letters. 6: 795-8. PMID 14986977 DOI: 10.1021/Ol036502+ |
0.504 |
|
| 2003 |
Lei X, Johnson RP, Porco JA. Total synthesis of the ubiquitin-activating enzyme inhibitor (+)-panepophenanthrin. Angewandte Chemie (International Ed. in English). 42: 3913-7. PMID 12949867 DOI: 10.1002/Anie.200351862 |
0.531 |
|
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