| Year |
Citation |
Score |
| 2023 |
Wei Y, Liu M, Yen EY, Yao J, Nguyen PT, Wang X, Yang Z, Yousef A, Pan D, Jin Y, Theady MS, Park J, Cai Y, Takeda M, Vasquez M, ... ... Ying H, et al. KRAS inhibition activates an actionable CD24 'don't eat me' signal in pancreas cancer. Biorxiv : the Preprint Server For Biology. PMID 37790498 DOI: 10.1101/2023.09.21.558891 |
0.315 |
|
| 2023 |
Li F, Wang Y, Hwang I, Jang JY, Xu L, Deng Z, Yu EY, Cai Y, Wu C, Han Z, Huang YH, Huang X, Zhang L, Yao J, Lue NF, ... ... Ying H, et al. Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance. Nature Communications. 14: 1756. PMID 36991019 DOI: 10.1038/s41467-023-37480-2 |
0.533 |
|
| 2023 |
Li F, Wang Y, Hwang I, Jang JY, Xu L, Deng Z, Yu EY, Cai Y, Wu C, Han Z, Huang YH, Huang X, Zhang L, Yao J, Lue NF, ... ... Ying H, et al. Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance. Biorxiv : the Preprint Server For Biology. PMID 36798426 DOI: 10.1101/2023.02.10.528023 |
0.534 |
|
| 2023 |
Sun C, Ye Y, Tan Z, Liu Y, Li Y, Hu W, Liang K, Egranov SD, Huang LA, Zhang Z, Zhang Y, Yao J, Nguyen TK, Zhao Z, Wu A, ... ... Ying H, et al. Tumor-associated nonmyelinating Schwann cell-expressed promotes pancreatic cancer kynurenine pathway and tumor immune exclusion. Science Advances. 9: eadd6995. PMID 36724291 DOI: 10.1126/sciadv.add6995 |
0.338 |
|
| 2022 |
Yuan M, Tu B, Li H, Pang H, Zhang N, Fan M, Bai J, Wang W, Shu Z, DuFort CC, Huo S, Zhai J, Yao K, Wang L, Ying H, et al. Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growth. Nature Cancer. PMID 35982178 DOI: 10.1038/s43018-022-00426-6 |
0.34 |
|
| 2022 |
Kerk S, Lin L, Myers AL, Sutton DJ, Andren A, Sajjakulnukit P, Zhang L, Zhang Y, Jiménez JA, Nelson BS, Chen B, Robinson A, Thurston G, Kemp SB, Steele NG, ... ... Ying H, et al. Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context. Elife. 11. PMID 35815941 DOI: 10.7554/eLife.73245 |
0.342 |
|
| 2022 |
Liu Y, Deguchi Y, Wei D, Liu F, Moussalli MJ, Deguchi E, Li D, Wang H, Valentin LA, Colby JK, Wang J, Zheng X, Ying H, Gagea M, Ji B, et al. Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARδ. Nature Communications. 13: 2665. PMID 35562376 DOI: 10.1038/s41467-022-30392-7 |
0.313 |
|
| 2021 |
Kim PK, Halbrook CJ, Kerk SA, Radyk M, Wisner S, Kremer DM, Sajjakulnukit P, Andren A, Hou SW, Trivedi A, Thurston G, Anand A, Yan L, Salamanca-Cardona L, Welling SD, ... ... Ying H, et al. Hyaluronic acid fuels pancreatic cancer cell growth. Elife. 10. PMID 34951587 DOI: 10.7554/eLife.62645 |
0.344 |
|
| 2021 |
Deng Y, Xia X, Zhao Y, Zhao Z, Martinez C, Yin W, Yao J, Hang Q, Wu W, Zhang J, Yu Y, Xia W, Yao F, Zhao D, Sun Y, ... Ying H, et al. Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance. Nature Communications. 12: 7041. PMID 34873175 DOI: 10.1038/s41467-021-27349-7 |
0.307 |
|
| 2021 |
Yan H, Yu CC, Fine SA, Youssof AL, Yang YR, Yan J, Karg DC, Cheung EC, Friedman RA, Ying H, Chen EI, Luo J, Miao Y, Qiu W, Su GH. Loss of the wild-type KRAS allele promotes pancreatic cancer progression through functional activation of YAP1. Oncogene. PMID 34663879 DOI: 10.1038/s41388-021-02040-9 |
0.389 |
|
| 2021 |
Giuliani V, Miller MA, Liu CY, Hartono SR, Class CA, Bristow CA, Suzuki E, Sanz LA, Gao G, Gay JP, Feng N, Rose JL, Tomihara H, Daniele JR, Peoples MD, ... ... Ying H, et al. PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma. Nature Communications. 12: 4626. PMID 34330913 DOI: 10.1038/s41467-021-24798-y |
0.318 |
|
| 2021 |
Yan L, Tu B, Yao J, Gong J, Carugo A, Bristow CA, Wang Q, Zhu C, Dai B, Kang Y, Han L, Feng N, Jin Y, Fleming J, Heffernan TP, ... ... Ying H, et al. Targeting glucose metabolism sensitizes pancreatic cancer to MEK inhibition. Cancer Research. PMID 34117030 DOI: 10.1158/0008-5472.CAN-20-3792 |
0.367 |
|
| 2021 |
Chang WH, Thi Nguyen TT, Hsu CH, Bryant KL, Kim HJ, Ying H, Erickson JW, Der CJ, Cerione RA, Antonyak MA. KRAS-dependent cancer cells promote survival by producing exosomes enriched in Survivin. Cancer Letters. PMID 34111513 DOI: 10.1016/j.canlet.2021.05.031 |
0.336 |
|
| 2021 |
Oh H, Hwang I, Jang JY, Wu L, Cao D, Yao J, Ying H, Li JY, Yao Y, Hu B, Wang Q, Zheng H, Paik J. Therapy-induced transdifferentiation promotes glioma growth independent of EGFR signaling. Cancer Research. PMID 33509942 DOI: 10.1158/0008-5472.CAN-20-1810 |
0.519 |
|
| 2020 |
Maitituoheti M, Keung EZ, Tang M, Yan L, Alam H, Han G, Singh AK, Raman AT, Terranova C, Sarkar S, Orouji E, Amin SB, Sharma S, Williams M, Samant NS, ... ... Ying H, et al. Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma. Cell Reports. 33: 108293. PMID 33086062 DOI: 10.1016/j.celrep.2020.108293 |
0.341 |
|
| 2020 |
Bryant KL, Stalnecker CA, Zeitouni D, Klomp JE, Peng S, Tikunov AP, Gunda V, Pierobon M, Waters AM, George SD, Tomar G, Papke B, Hobbs GA, Yan L, Hayes TK, ... ... Ying H, et al. Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer. Nature Medicine. PMID 32483362 DOI: 10.1038/S41591-020-0947-8 |
0.338 |
|
| 2020 |
Yao W, Maitra A, Ying H. Recent insights into the biology of pancreatic cancer. Ebiomedicine. 102655. PMID 32139179 DOI: 10.1016/J.Ebiom.2020.102655 |
0.37 |
|
| 2020 |
Dey P, Li J, Zhang J, Chaurasiya S, Strom A, Wang H, Liao WT, Cavallaro F, Denz P, Bernard V, Yen EY, Genovese G, Gulhati P, Liu J, Chakravarti D, ... ... Ying H, et al. Oncogenic Kras driven metabolic reprogramming in pancreas cancer cells utilizes cytokines from the tumor microenvironment. Cancer Discovery. PMID 32046984 DOI: 10.1158/2159-8290.Cd-19-0297 |
0.421 |
|
| 2020 |
Wang G, Lu X, Chakravarti D, Kapoor A, Yao W, Ying H, Dey P, Wu C, Spring D, Hou P, Deng P, Zhao D, Hu B, Xizeng M, Logothesis C, et al. Abstract IA24: YAP in cancer and inflammation Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-Ia24 |
0.402 |
|
| 2020 |
Boutin A, Chen P, Dey P, Hou P, Liao W, Lu X, Ying H, Zhao D, DePinho RA. Abstract IA01: Modeling and understanding tumor biologic mechanisms Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-Ia01 |
0.448 |
|
| 2019 |
Kapoor A, Yao W, Ying H, Hua S, Liewen A, Wang Q, Zhong Y, Wu CJ, Sadanandam A, Hu B, Chang Q, Chu GC, Al-Khalil R, Jiang S, Xia H, et al. Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer. Cell. 179: 1239. PMID 31730860 DOI: 10.1016/J.Cell.2019.10.037 |
0.379 |
|
| 2019 |
Yan L, Raj P, Yao W, Ying H. Glucose Metabolism in Pancreatic Cancer. Cancers. 11. PMID 31569510 DOI: 10.3390/Cancers11101460 |
0.43 |
|
| 2019 |
Tu B, Yao J, Ferri-Borgogno S, Zhao J, Chen S, Wang Q, Yan L, Zhou X, Zhu C, Bang S, Chang Q, Bristow CA, Kang Y, Zheng H, Wang H, ... ... Ying H, et al. YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma. Jci Insight. PMID 31557131 DOI: 10.1172/Jci.Insight.130811 |
0.623 |
|
| 2019 |
Li F, Deng Z, Zhang L, Wu C, Jin Y, Hwang I, Vladimirova O, Xu L, Yang L, Lu B, Dheekollu J, Li JY, Feng H, Hu J, Vakoc CR, ... Ying H, et al. ATRX loss induces telomere dysfunction and necessitates induction of alternative lengthening of telomeres during human cell immortalization. The Embo Journal. e96659. PMID 31454099 DOI: 10.15252/Embj.201796659 |
0.568 |
|
| 2019 |
Yu M, Nguyen ND, Huang Y, Lin D, Fujimoto TN, Molkentine JM, Deorukhkar A, Kang Y, San Lucas FA, Fernandes CJ, Koay EJ, Gupta S, Ying H, Koong AC, Herman JM, et al. Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer. Jci Insight. 5. PMID 31335325 DOI: 10.1172/Jci.Insight.126915 |
0.361 |
|
| 2019 |
Yao W, Rose JL, Wang W, Seth S, Jiang H, Taguchi A, Liu J, Yan L, Kapoor A, Hou P, Chen Z, Wang Q, Nezi L, Xu Z, Yao J, ... ... Ying H, et al. Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer. Nature. PMID 30918400 DOI: 10.1038/S41586-019-1062-1 |
0.434 |
|
| 2019 |
Bryant KL, Stalnecker CA, Zeitouni D, Klomp JE, Peng S, Tikunov AP, Gunda V, Pierobon M, Waters AM, George SD, Tomar G, Papke B, Hobbs GA, Yan L, Hayes TK, ... ... Ying H, et al. Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer. Nature Medicine. PMID 30833752 DOI: 10.1038/S41591-019-0368-8 |
0.402 |
|
| 2019 |
Chen Z, Liu J, Ho I, Rose J, Yan L, Yao W, Viale A, Carugo A, Ying H, Draetta G. Abstract C12: Lipids signaling contributes to glucose-independent metabolic adaptation in pancreatic ductal adenocarcinoma Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-C12 |
0.399 |
|
| 2018 |
Santana-Codina N, Roeth AA, Zhang Y, Yang A, Mashadova O, Asara JM, Wang X, Bronson RT, Lyssiotis CA, Ying H, Kimmelman AC. Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis. Nature Communications. 9: 4945. PMID 30470748 DOI: 10.1038/S41467-018-07472-8 |
0.436 |
|
| 2018 |
Xing Z, Zhang Y, Liang K, Yan L, Xiang Y, Li C, Hu Q, Jin F, Putluri V, Putluri N, Coarfa C, Sreekumar A, Park PK, Nguyen TK, Wang S, ... ... Ying H, et al. Expression of long non-coding RNA YIYA promotes glycolysis in breast cancer. Cancer Research. PMID 29967256 DOI: 10.1158/0008-5472.Can-17-0385 |
0.426 |
|
| 2018 |
Wang YN, Lee HH, Chou CK, Yang WH, Wei Y, Chen CT, Yao J, Hsu JL, Zhu C, Ying H, Ye Y, Wang WJ, Lim SO, Xia W, Ko HW, et al. Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer. Cancer Cell. PMID 29606349 DOI: 10.1016/J.Ccell.2018.02.012 |
0.311 |
|
| 2018 |
Zhao N, Cao J, Xu L, Tang Q, Dobrolecki LE, Lv X, Talukdar M, Lu Y, Wang X, Hu DZ, Shi Q, Xiang Y, Wang Y, Liu X, Bu W, ... ... Ying H, et al. Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. The Journal of Clinical Investigation. PMID 29480818 DOI: 10.1172/Jci95873 |
0.505 |
|
| 2018 |
Dey P, Baddour J, Kim Y, Macloed R, Muller F, Wu CC, Wang H, Viale A, Ying H, Draetta G, Maitra A, Wang A, Nagrath D, DePinho R. Abstract 777: Malic enzyme 3 as a collateral lethality target in pancreatic cancer Cancer Research. 78: 777-777. DOI: 10.1158/1538-7445.Am2018-777 |
0.471 |
|
| 2017 |
Ju HQ, Ying H, Tian T, Ling J, Fu J, Lu Y, Wu M, Yang L, Achreja A, Chen G, Zhuang Z, Wang H, Nagrath D, Yao J, Hung MC, et al. Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma. Nature Communications. 8: 14437. PMID 28232723 DOI: 10.1038/Ncomms14437 |
0.405 |
|
| 2017 |
Genovese G, Carugo A, Tepper J, Robinson FS, Li L, Svelto M, Nezi L, Corti D, Minelli R, Pettazzoni P, Gutschner T, Wu CC, Seth S, Akdemir KC, Leo E, ... ... Ying H, et al. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. Nature. PMID 28178232 DOI: 10.1038/Nature21064 |
0.451 |
|
| 2017 |
Dey P, Baddour J, Muller F, Wu CC, Wang H, Liao WT, Lan Z, Chen A, Gutschner T, Kang Y, Fleming J, Satani N, Zhao D, Achreja A, Yang L, ... ... Ying H, et al. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. PMID 28099419 DOI: 10.1038/Nature21052 |
0.374 |
|
| 2016 |
Mann KM, Ying H, Juan J, Jenkins NA, Copeland NG. KRAS-related proteins in pancreatic cancer. Pharmacology & Therapeutics. PMID 27595930 DOI: 10.1016/J.Pharmthera.2016.09.003 |
0.329 |
|
| 2016 |
Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC. Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature. PMID 27509858 DOI: 10.1038/Nature19084 |
0.371 |
|
| 2016 |
Jiang X, Niu M, Chen D, Chen J, Cao Y, Li X, Ying H, Bergholz J, Zhang Y, Xiao ZX. Inhibition of Cdc42 is essential for Mig-6 suppression of cell migration induced by EGF. Oncotarget. PMID 27341132 DOI: 10.18632/Oncotarget.10205 |
0.429 |
|
| 2016 |
Ying H, Dey P, Yao W, Kimmelman AC, Draetta GF, Maitra A, DePinho RA. Genetics and biology of pancreatic ductal adenocarcinoma. Genes & Development. 30: 355-85. PMID 26883357 DOI: 10.1101/Gad.275776.115 |
0.332 |
|
| 2016 |
Tsang YH, Dogruluk T, Tedeschi PM, Wardwell-Ozgo J, Lu H, Espitia M, Nair N, Minelli R, Chong Z, Chen F, Chang QE, Dennison JB, Dogruluk A, Li M, Ying H, et al. Functional annotation of rare gene aberration drivers of pancreatic cancer. Nature Communications. 7: 10500. PMID 26806015 DOI: 10.1038/Ncomms10500 |
0.451 |
|
| 2015 |
Klingler S, Guo B, Yao J, Yan H, Zhang L, Vaseva AV, Chen S, Canoll P, Horner JW, Wang YA, Paik JH, Ying H, Zheng H. Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms. Cancer Research. 75: 2109-19. PMID 25808866 DOI: 10.1158/0008-5472.Can-14-3122 |
0.514 |
|
| 2015 |
Pettazzoni P, Viale A, Shah P, Carugo A, Ying H, Wang H, Genovese G, Seth S, Minelli R, Green T, Huang-Hobbs E, Corti D, Sanchez N, Nezi L, Marchesini M, et al. Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer. Cancer Research. 75: 1091-101. PMID 25736685 DOI: 10.1158/0008-5472.Can-14-1854 |
0.424 |
|
| 2015 |
Tong Y, Ying H, Liu R, Li L, Bergholz J, Xiao ZX. Pin1 inhibits PP2A-mediated Rb dephosphorylation in regulation of cell cycle and S-phase DNA damage. Cell Death & Disease. 6: e1640. PMID 25675300 DOI: 10.1038/Cddis.2015.3 |
0.427 |
|
| 2015 |
Viale A, Pettazzoni P, Lyssiotis C, Ying H, Sánchez N, Marchesini M, Carugo A, Green T, Seth S, Giuliani V, Heffernan T, Kimmelman A, Wang H, Fleming J, Cantley L, et al. Abstract PR13: Pancreatic tumor stem cells resistant to inhibition of oncogenic signaling are dependent on mitochondrial function Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-Pr13 |
0.461 |
|
| 2015 |
Lyssiotis CA, Son J, Mancias JD, Ying H, Cantley LC, Kimmelman AC. Abstract B45: Pancreatic cancers depend on a non-canonical glutamine metabolism pathway Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B45 |
0.423 |
|
| 2015 |
Kapoor A, Yao W, Ying H, Hua S, Liewen A, Sadanandam A, Al-Khalil R, Viale A, Pettazzoni P, Sanchez N, Protopopov A, Zhang J, Heffernan T, Johnson RL, Chin L, et al. Abstract A94: Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A94 |
0.492 |
|
| 2015 |
Yao W, Wang W, Taguchi A, Kapoor A, Momin A, Jiang H, Rose J, Celiktas M, Deem A, Hanash S, DePinho R, Ying H, Draetta G. Abstract A18: Syndecan-1 is required for oncogenic Kras-driven PDAC tumorigenesis and maintenance Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A18 |
0.477 |
|
| 2015 |
Yao W, Ying H, Draetta G. Abstract C157: Syndecan1 is required for oncogenic Kras-driven PDAC tumorigenesis and maintenance Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-C157 |
0.485 |
|
| 2014 |
Viale A, Pettazzoni P, Lyssiotis CA, Ying H, Sánchez N, Marchesini M, Carugo A, Green T, Seth S, Giuliani V, Kost-Alimova M, Muller F, Colla S, Nezi L, Genovese G, et al. Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function. Nature. 514: 628-32. PMID 25119024 DOI: 10.1038/Nature13611 |
0.423 |
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| 2014 |
Ying H, DePinho RA. Cancer signaling: when phosphorylation meets methylation. Cell Research. 24: 1282-3. PMID 25104733 DOI: 10.1038/Cr.2014.103 |
0.379 |
|
| 2014 |
Kapoor A, Yao W, Ying H, Hua S, Liewen A, Wang Q, Zhong Y, Wu CJ, Sadanandam A, Hu B, Chang Q, Chu GC, Al-Khalil R, Jiang S, Xia H, et al. Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer. Cell. 158: 185-97. PMID 24954535 DOI: 10.1016/J.Cell.2014.06.003 |
0.479 |
|
| 2014 |
Stopczynski RE, Normolle DP, Hartman DJ, Ying H, DeBerry JJ, Bielefeldt K, Rhim AD, DePinho RA, Albers KM, Davis BM. Neuroplastic changes occur early in the development of pancreatic ductal adenocarcinoma. Cancer Research. 74: 1718-27. PMID 24448244 DOI: 10.1158/0008-5472.Can-13-2050 |
0.343 |
|
| 2014 |
Lyssiotis C, Son J, Mancias J, Ying H, Kimmelman A, Cantley L. Pancreatic cancers depend on a non-canonical glutamine metabolism pathway Cancer & Metabolism. 2. DOI: 10.1186/2049-3002-2-S1-P44 |
0.433 |
|
| 2014 |
Taguchi A, Kapoor A, Momin A, Katayama H, Yao W, Wang H, Ying H, DePinho R, Hanash S. Abstract PR03: Global quantitative proteomic and phosphoproteomic analysis of oncogenic Kras-driven mouse pancreatic cancer Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-Pr03 |
0.442 |
|
| 2014 |
Kapoor A, Yao W, Ying H, Hua S, Liewen A, Wang Q, Zhong Y, Wu C, Sadanandam A, Hu B, Chang Q, Chu G, Al-Khalil R, Jiang S, Xia H, et al. Abstract PR01: Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-Pr01 |
0.489 |
|
| 2014 |
Taguchi A, Kapoor A, Momin A, Katayama H, Yao W, Wang H, Ying H, DePinho R, Hanash S. Tu1678 Global Quantitative Proteomic and Phosphoproteomic Analysis of Oncogenic Kras-Driven Mouse Pancreatic Cancer Gastroenterology. 146: S-816. DOI: 10.1016/S0016-5085(14)62954-1 |
0.366 |
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| 2013 |
Jun S, Lee S, Kim HC, Ng C, Schneider AM, Ji H, Ying H, Wang H, DePinho RA, Park JI. PAF-mediated MAPK signaling hyperactivation via LAMTOR3 induces pancreatic tumorigenesis. Cell Reports. 5: 314-22. PMID 24209743 DOI: 10.1016/J.Celrep.2013.09.026 |
0.442 |
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| 2013 |
Yeo H, Lyssiotis CA, Zhang Y, Ying H, Asara JM, Cantley LC, Paik JH. FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells. The Embo Journal. 32: 2589-602. PMID 24013118 DOI: 10.1038/Emboj.2013.186 |
0.322 |
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| 2013 |
Zhang Y, Shin SJ, Liu D, Ivanova E, Foerster F, Ying H, Zheng H, Xiao Y, Chen Z, Protopopov A, Depinho RA, Paik JH. ZNF365 promotes stability of fragile sites and telomeres. Cancer Discovery. 3: 798-811. PMID 23776040 DOI: 10.1158/2159-8290.Cd-12-0536 |
0.601 |
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| 2013 |
Du W, Yi Y, Zhang H, Bergholz J, Wu J, Ying H, Zhang Y, Xiao ZX. Rapamycin inhibits IGF-1-mediated up-regulation of MDM2 and sensitizes cancer cells to chemotherapy. Plos One. 8: e63179. PMID 23638184 DOI: 10.1371/Journal.Pone.0063179 |
0.497 |
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| 2013 |
Son J, Lyssiotis CA, Ying H, Wang X, Hua S, Ligorio M, Perera RM, Ferrone CR, Mullarky E, Shyh-Chang N, Kang Y, Fleming JB, Bardeesy N, Asara JM, Haigis MC, et al. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature. 496: 101-5. PMID 23535601 DOI: 10.1038/Nature12040 |
0.415 |
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| 2013 |
Du W, Yi Y, Zhang H, Bergholz J, Wu J, Ying H, Zhang Y, Xiao ZJ. Correction: Rapamycin Inhibits IGF-1-Mediated Up-Regulation of MDM2 and Sensitizes Cancer Cells to Chemotherapy Plos One. 8. DOI: 10.1371/annotation/f1a4d192-57b9-43fb-a248-379e0f5a46ca |
0.705 |
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| 2013 |
Son J, Lyssiotis CA, Ying H, Wang X, Hua S, Ligorio M, Perera RM, Ferrone CR, Mullarky E, Shyh-Chang N, Kang Y, Fleming JB, Bardeesy N, Asara JM, Haigis MC, et al. Erratum: Corrigendum: Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway Nature. 499: 504-504. DOI: 10.1038/Nature12317 |
0.397 |
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| 2012 |
Chen AJ, Paik JH, Zhang H, Shukla SA, Mortensen R, Hu J, Ying H, Hu B, Hurt J, Farny N, Dong C, Xiao Y, Wang YA, Silver PA, Chin L, et al. STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA. Genes & Development. 26: 1459-72. PMID 22751500 DOI: 10.1101/Gad.189001.112 |
0.421 |
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| 2012 |
Genovese G, Ergun A, Shukla SA, Campos B, Hanna J, Ghosh P, Quayle SN, Rai K, Colla S, Ying H, Wu CJ, Sarkar S, Xiao Y, Zhang J, Zhang H, et al. microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma. Cancer Discovery. 2: 736-49. PMID 22750848 DOI: 10.1158/2159-8290.Cd-12-0111 |
0.496 |
|
| 2012 |
Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, et al. Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell. 149: 656-70. PMID 22541435 DOI: 10.1016/J.Cell.2012.01.058 |
0.609 |
|
| 2012 |
Hu J, Hwang SS, Liesa M, Gan B, Sahin E, Jaskelioff M, Ding Z, Ying H, Boutin AT, Zhang H, Johnson S, Ivanova E, Kost-Alimova M, Protopopov A, Wang YA, et al. Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer. Cell. 148: 651-63. PMID 22341440 DOI: 10.1016/J.Cell.2011.12.028 |
0.435 |
|
| 2012 |
Tai Y, Landesman Y, Acharya C, Zhong MY, Calle Y, Cea M, Hu Y, Cagnetta A, Tannenbaum D, Chen M, Munshi A, Senapedis W, Saint-Martin J, Kashyap T, Ying H, et al. CRM1 Blockade by Novel Inhibitors of Nuclear Export (SINEs) Inhibits Multiple Myeloma Cell Growth, Osteoclastogenesis, and Myeloma-Induced Osteolysis Blood. 120: 326-326. DOI: 10.1182/Blood.V120.21.326.326 |
0.3 |
|
| 2012 |
Stopczynski RE, Albers KM, Bielefeldt K, DePinho RA, Ying H, Davis BM. Abstract PR4: Neuroplastic changes and pain-related behavior in a transgenic mouse model of pancreatic ductal adenocarcinoma (PDAC). Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-Pr4 |
0.331 |
|
| 2012 |
Son J, Lyssiotis CA, Yang S, Ying H, Wang X, Cantley LC, Kimmelman AC. Abstract IA14: Autophagy, metabolism, and pancreatic cancer. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-Ia14 |
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Lyssiotis C, Ying H, Kimmelman A, DePinho R, Cantley L. Abstract A51: Oncogenic Kras is required for pancreatic tumor maintenance through the regulation of anabolic glucose metabolism. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A51 |
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Ying H, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik J, Lim C, Guimaraes AR, Kimmelman AC, Martin ES, Chang J, Hezel A, et al. Abstract A101: Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A101 |
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Chen S, Johnson N, Auger KR, Xiao Y, Ying H, Marszalek J, Middleton R, Andersen JN, McGrath JP, Chin L. Abstract 3714: Characterization of a selective focal adhesion kinase (FAK) inhibitor in a panel of glioblastoma cell lines identify rational drug-drug combination strategies Cancer Research. 72: 3714-3714. DOI: 10.1158/1538-7445.Am2012-3714 |
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Ying H, Elpek KG, Vinjamoori A, Zimmerman SM, Chu GC, Yan H, Fletcher-Sananikone E, Zhang H, Liu Y, Wang W, Ren X, Zheng H, Kimmelman AC, Paik JH, Lim C, et al. PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network. Cancer Discovery. 1: 158-69. PMID 21984975 DOI: 10.1158/2159-8290.Cd-11-0031 |
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Yang S, Wang X, Contino G, Liesa M, Sahin E, Ying H, Bause A, Li Y, Stommel JM, Dell'antonio G, Mautner J, Tonon G, Haigis M, Shirihai OS, Doglioni C, et al. Pancreatic cancers require autophagy for tumor growth. Genes & Development. 25: 717-29. PMID 21406549 DOI: 10.1101/Gad.2016111 |
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Zheng H, Ying H, Wiedemeyer R, Yan H, Quayle SN, Ivanova EV, Paik JH, Zhang H, Xiao Y, Perry SR, Hu J, Vinjamoori A, Gan B, Sahin E, Chheda MG, et al. PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas. Cancer Cell. 17: 497-509. PMID 20478531 DOI: 10.1016/J.Ccr.2010.03.020 |
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Ying H, Zheng H, Scott K, Wiedemeyer R, Yan H, Lim C, Huang J, Dhakal S, Ivanova E, Xiao Y, Zhang H, Hu J, Stommel JM, Lee MA, Chen AJ, et al. Mig-6 controls EGFR trafficking and suppresses gliomagenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 6912-7. PMID 20351267 DOI: 10.1073/Pnas.0914930107 |
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Stopczynski RE, DePinho RA, Ying H, Schwartz ES, Albers KM, Davis BM, Bielefeldt K. 412 Neuroplastic Changes in a Mouse Model of Pancreatic Ductal Adenocarcinoma (PDAC) Gastroenterology. 138: S-62. DOI: 10.1016/S0016-5085(10)60280-6 |
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Paik JH, Ding Z, Narurkar R, Ramkissoon S, Muller F, Kamoun WS, Chae SS, Zheng H, Ying H, Mahoney J, Hiller D, Jiang S, Protopopov A, Wong WH, Chin L, et al. FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. Cell Stem Cell. 5: 540-53. PMID 19896444 DOI: 10.1016/J.Stem.2009.09.013 |
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Mineva ND, Wang X, Yang S, Ying H, Xiao ZX, Holick MF, Sonenshein GE. Inhibition of RelB by 1,25-dihydroxyvitamin D3 promotes sensitivity of breast cancer cells to radiation. Journal of Cellular Physiology. 220: 593-9. PMID 19373868 DOI: 10.1002/Jcp.21765 |
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Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, et al. Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma. Cold Spring Harbor Symposia On Quantitative Biology. 73: 427-37. PMID 19150964 DOI: 10.1101/Sqb.2008.73.047 |
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Kimmelman AC, Hezel AF, Aguirre AJ, Zheng H, Paik JH, Ying H, Chu GC, Zhang JX, Sahin E, Yeo G, Ponugoti A, Nabioullin R, Deroo S, Yang S, Wang X, et al. Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer. Proceedings of the National Academy of Sciences of the United States of America. 105: 19372-7. PMID 19050074 DOI: 10.1073/Pnas.0809966105 |
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Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, et al. p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature. 455: 1129-33. PMID 18948956 DOI: 10.1038/Nature07443 |
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Stommel JM, Kimmelman AC, Ying H, Nabioullin R, Ponugoti AH, Wiedemeyer R, Stegh AH, Bradner JE, Ligon KL, Brennan C, Chin L, DePinho RA. Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science (New York, N.Y.). 318: 287-90. PMID 17872411 DOI: 10.1126/Science.1142946 |
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Chang DL, Qiu W, Ying H, Zhang Y, Chen CY, Xiao ZX. ARF promotes accumulation of retinoblastoma protein through inhibition of MDM2. Oncogene. 26: 4627-34. PMID 17297463 DOI: 10.1038/Sj.Onc.1210254 |
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Ying H, Xiao ZX. Targeting retinoblastoma protein for degradation by proteasomes. Cell Cycle (Georgetown, Tex.). 5: 506-8. PMID 16552188 DOI: 10.4161/Cc.5.5.2515 |
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Sdek P, Ying H, Chang DL, Qiu W, Zheng H, Touitou R, Allday MJ, Xiao ZX. MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein. Molecular Cell. 20: 699-708. PMID 16337594 DOI: 10.1016/J.Molcel.2005.10.017 |
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Currier N, Solomon SE, Demicco EG, Chang DL, Farago M, Ying H, Dominguez I, Sonenshein GE, Cardiff RD, Xiao ZX, Sherr DH, Seldin DC. Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors. Toxicologic Pathology. 33: 726-37. PMID 16263698 DOI: 10.1080/01926230500352226 |
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Ying H, Chang DL, Zheng H, McKeon F, Xiao ZX. DNA-binding and transactivation activities are essential for TAp63 protein degradation. Molecular and Cellular Biology. 25: 6154-64. PMID 15988026 DOI: 10.1128/Mcb.25.14.6154-6164.2005 |
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Murray SA, Yang S, Demicco E, Ying H, Sherr DH, Hafer LJ, Rogers AE, Sonenshein GE, Xiao ZX. Increased expression of MDM2, cyclin D1, and p27Kip1 in carcinogen-induced rat mammary tumors. Journal of Cellular Biochemistry. 95: 875-84. PMID 15844214 DOI: 10.1002/Jcb.20414 |
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Sdek P, Ying H, Zheng H, Margulis A, Tang X, Tian K, Xiao ZX. The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth. The Journal of Biological Chemistry. 279: 53317-22. PMID 15485814 DOI: 10.1074/Jbc.M406062200 |
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Gu L, Ying H, Zheng H, Murray SA, Xiao ZX. The MDM2 RING finger is required for cell cycle-dependent regulation of its protein expression. Febs Letters. 544: 218-22. PMID 12782320 DOI: 10.1016/S0014-5793(03)00502-7 |
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Gu L, Zheng H, Murray SA, Ying H, Jim Xiao ZX. Deregulation of Cdc2 kinase induces caspase-3 activation and apoptosis. Biochemical and Biophysical Research Communications. 302: 384-91. PMID 12604359 DOI: 10.1016/S0006-291X(03)00189-X |
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