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Wah Chiu, PhD - Publications

Affiliations: 
1989-2016 Biochemistry and Molecular Biology Baylor College of Medicine, Houston, TX 
 2017- Bioengineering Stanford University, Palo Alto, CA 
Area:
Electron Cryo-Microscopy of Biological Machines and Cells
Website:
https://profiles.stanford.edu/wah-chiu
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Year Citation  Score
2023 Kretsch RC, Andersen ES, Bujnicki JM, Chiu W, Das R, Luo B, Masquida B, McRae EKS, Schroeder GM, Su Z, Wedekind JE, Xu L, Zhang K, Zheludev IN, Moult J, et al. RNA target highlights in CASP15: Evaluation of predicted models by structure providers. Proteins. PMID 37466021 DOI: 10.1002/prot.26550  0.65
2023 Gestaut D, Zhao Y, Park J, Ma B, Leitner A, Collier M, Pintilie G, Roh SH, Chiu W, Frydman J. Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell. 186: 2038. PMID 37116473 DOI: 10.1016/j.cell.2023.04.004  0.67
2022 Kaelber JT, Chmielewski D, Chiu W, Auguste AJ. Alphavirus Particles Can Assemble with an Alternate Triangulation Number. Viruses. 14. PMID 36560655 DOI: 10.3390/v14122650  0.696
2022 Gestaut D, Zhao Y, Park J, Ma B, Leitner A, Collier M, Pintilie G, Roh SH, Chiu W, Frydman J. Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell. 185: 4770-4787.e20. PMID 36493755 DOI: 10.1016/j.cell.2022.11.014  0.697
2022 Burley SK, Berman HM, Chiu W, Dai W, Flatt JW, Hudson BP, Kaelber JT, Khare SD, Kulczyk AW, Lawson CL, Pintilie GD, Sali A, Vallat B, Westbrook JD, Young JY, et al. Electron microscopy holdings of the Protein Data Bank: the impact of the resolution revolution, new validation tools, and implications for the future. Biophysical Reviews. 1-21. PMID 36474933 DOI: 10.1007/s12551-022-01013-w  0.737
2022 Li S, Palo MZ, Pintilie G, Zhang X, Su Z, Kappel K, Chiu W, Zhang K, Das R. Topological crossing in the misfolded ribozyme resolved by cryo-EM. Proceedings of the National Academy of Sciences of the United States of America. 119: e2209146119. PMID 36067294 DOI: 10.1073/pnas.2209146119  0.636
2022 Zhou W, Bammes B, Mitchell PG, Betz K, Chiu W. Corrigendum to "Electron crystallography of chiral and non-chiral small molecules" [Ultramicroscopy 232 (2022) 113417]. Ultramicroscopy. 113474. PMID 35090780 DOI: 10.1016/j.ultramic.2022.113474  0.695
2022 Wang Y, Binning JM, Pintilie GD, Chiu W, Amarasinghe GK, Leung DW, Su Z. Cryo-EM analysis of Ebola virus nucleocapsid-like assembly. Star Protocols. 3: 101030. PMID 34977676 DOI: 10.1016/j.xpro.2021.101030  0.673
2021 Cogan DP, Zhang K, Li X, Li S, Pintilie GD, Roh SH, Craik CS, Chiu W, Khosla C. Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science (New York, N.Y.). 374: 729-734. PMID 34735239 DOI: 10.1126/science.abi8358  0.669
2021 Zhou W, Bammes B, Mitchell PG, Betz K, Chiu W. Electron crystallography of chiral and non-chiral small molecules. Ultramicroscopy. 232: 113417. PMID 34695647 DOI: 10.1016/j.ultramic.2021.113417  0.734
2021 Su Z, Zhang K, Kappel K, Li S, Palo MZ, Pintilie GD, Rangan R, Luo B, Wei Y, Das R, Chiu W. Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 Å resolution. Nature. PMID 34381213 DOI: 10.1038/s41586-021-03803-w  0.695
2021 Torabi SF, Chen YL, Zhang K, Wang J, DeGregorio SJ, Vaidya AT, Su Z, Pabit SA, Chiu W, Pollack L, Steitz JA. Structural analyses of an RNA stability element interacting with poly(A). Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33785601 DOI: 10.1073/pnas.2026656118  0.662
2021 Oliver SL, Xing Y, Chen DH, Roh SH, Pintilie GD, Bushnell DA, Sommer MH, Yang E, Carfi A, Chiu W, Arvin AM. The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion. Plos Pathogens. 17: e1008961. PMID 33411789 DOI: 10.1371/journal.ppat.1008961  0.707
2020 Roh SH, Shekhar M, Pintilie G, Chipot C, Wilkens S, Singharoy A, Chiu W. Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of V complex. Science Advances. 6. PMID 33028525 DOI: 10.1126/sciadv.abb9605  0.69
2020 Selzer L, Su Z, Pintilie GD, Chiu W, Kirkegaard K. Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer. Plos Biology. 18: e3000827. PMID 32997652 DOI: 10.1371/journal.pbio.3000827  0.661
2020 Oliver SL, Xing Y, Chen DH, Roh SH, Pintilie GD, Bushnell DA, Sommer MH, Yang E, Carfi A, Chiu W, Arvin AM. Publisher Correction: A glycoprotein B-neutralizing antibody structure at 2.8 Å uncovers a critical domain for herpesvirus fusion initiation. Nature Communications. 11: 4398. PMID 32859924 DOI: 10.1038/S41467-020-18385-W  0.698
2020 Wu GH, Mitchell PG, Galaz-Montoya JG, Hecksel CW, Sontag EM, Gangadharan V, Marshman J, Mankus D, Bisher ME, Lytton-Jean AKR, Frydman J, Czymmek K, Chiu W. Multi-scale 3D Cryo-Correlative Microscopy for Vitrified Cells. Structure (London, England : 1993). PMID 32814034 DOI: 10.1016/J.Str.2020.07.017  0.325
2020 Oliver SL, Xing Y, Chen DH, Roh SH, Pintilie GD, Bushnell DA, Sommer MH, Yang E, Carfi A, Chiu W, Arvin AM. A glycoprotein B-neutralizing antibody structure at 2.8 Å uncovers a critical domain for herpesvirus fusion initiation. Nature Communications. 11: 4141. PMID 32811830 DOI: 10.1038/S41467-020-17911-0  0.729
2020 Li Y, Huang W, Li Y, Chiu W, Cui Y. Opportunities for Cryogenic Electron Microscopy in Materials Science and Nanoscience. Acs Nano. PMID 32806083 DOI: 10.1021/Acsnano.0C05020  0.313
2020 Kappel K, Zhang K, Su Z, Watkins AM, Kladwang W, Li S, Pintilie G, Topkar VV, Rangan R, Zheludev IN, Yesselman JD, Chiu W, Das R. Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures. Nature Methods. 17: 699-707. PMID 32616928 DOI: 10.1038/S41592-020-0878-9  0.688
2020 Huang CS, Yu X, Fordstrom P, Choi K, Chung BC, Roh SH, Chiu W, Zhou M, Min X, Wang Z. Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition. Science Advances. 6: eabb1989. PMID 32596471 DOI: 10.1126/Sciadv.Abb1989  0.703
2020 Dahlberg PD, Saurabh S, Sartor AM, Wang J, Mitchell PG, Chiu W, Shapiro L, Moerner WE. Cryogenic single-molecule fluorescence annotations for electron tomography reveal in situ organization of key proteins in . Proceedings of the National Academy of Sciences of the United States of America. PMID 32513734 DOI: 10.1073/Pnas.2001849117  0.342
2020 Dahlberg PD, Perez D, Su Z, Chiu W, Moerner WE. Cryogenic Correlative Single-Particle Photoluminescence Spectroscopy and Electron Tomography for Investigation of Nanomaterials. Angewandte Chemie (International Ed. in English). PMID 32330371 DOI: 10.1002/Anie.202002856  0.677
2020 Zhang K, Wang S, Li S, Zhu Y, Pintilie GD, Mou TC, Schmid MF, Huang Z, Chiu W. Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM. Proceedings of the National Academy of Sciences of the United States of America. PMID 32170016 DOI: 10.1073/Pnas.1922638117  0.33
2020 Kaelber JT, Jiang W, Weaver SC, Auguste AJ, Chiu W. Arrangement of the Polymerase Complexes inside a Nine-Segmented dsRNA Virus. Structure (London, England : 1993). PMID 32049031 DOI: 10.1016/J.Str.2020.01.011  0.742
2020 Pintilie G, Zhang K, Su Z, Li S, Schmid MF, Chiu W. Measurement of atom resolvability in cryo-EM maps with Q-scores. Nature Methods. PMID 32042190 DOI: 10.1038/S41592-020-0731-1  0.669
2020 Lawson CL, Berman HM, Chiu W. Evolving data standards for cryo-EM structures. Structural Dynamics (Melville, N.Y.). 7: 014701. PMID 32002441 DOI: 10.1063/1.5138589  0.383
2020 Zhang H, Pan Y, Hu L, Hudson MA, Hofstetter KS, Xu Z, Rong M, Wang Z, Prasad BVV, Lockless SW, Chiu W, Zhou M. TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nature Communications. 11: 547. PMID 31992706 DOI: 10.1038/S41467-019-14240-9  0.711
2020 Bammes B, Zhou W, Chiu W. Sub-Ångström-Resolution MicroED Using a Direct Detection Camera Microscopy and Microanalysis. 1-4. DOI: 10.1017/S1431927620018401  0.702
2019 Zhang K, Li S, Kappel K, Pintilie G, Su Z, Mou TC, Schmid MF, Das R, Chiu W. Cryo-EM structure of a 40 kDa SAM-IV riboswitch RNA at 3.7 Å resolution. Nature Communications. 10: 5511. PMID 31796736 DOI: 10.1038/S41467-019-13494-7  0.703
2019 Berman HM, Adams PD, Bonvin AA, Burley SK, Carragher B, Chiu W, DiMaio F, Ferrin TE, Gabanyi MJ, Goddard TD, Griffin PR, Haas J, Hanke CA, Hoch JC, Hummer G, et al. Federating Structural Models and Data: Outcomes from A Workshop on Archiving Integrative Structures. Structure (London, England : 1993). PMID 31780431 DOI: 10.1016/J.Str.2019.11.002  0.337
2019 Li S, Su Z, Lehmann J, Stamatopoulou V, Giarimoglou N, Henderson FE, Fan L, Pintilie GD, Zhang K, Chen M, Ludtke SJ, Wang YX, Stathopoulos C, Chiu W, Zhang J. Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions. Nature Structural & Molecular Biology. PMID 31740854 DOI: 10.2210/Pdb6Pom/Pdb  0.735
2019 Kryshtafovych A, Malhotra S, Monastyrskyy B, Cragnolini T, Joseph AP, Chiu W, Topf M. Cryo-EM targets in CASP13: overview and evaluation of results. Proteins. PMID 31576602 DOI: 10.1002/Prot.25817  0.364
2019 Pintilie G, Chen DH, Tran BN, Jakana J, Wu J, Hew CL, Chiu W. Segmentation and Comparative Modeling in an 8.6-Å Cryo-EM Map of the Singapore Grouper Iridovirus. Structure (London, England : 1993). PMID 31447288 DOI: 10.1016/J.Str.2019.08.002  0.334
2019 Gestaut D, Roh SH, Ma B, Pintilie G, Joachimiak LA, Leitner A, Walzthoeni T, Aebersold R, Chiu W, Frydman J. The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell. PMID 30955883 DOI: 10.1016/J.Cell.2019.03.012  0.716
2019 Guo M, Zhang K, Zhu Y, Pintilie GD, Guan X, Li S, Schmid MF, Ma Z, Chiu W, Huang Z. Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry. Cell Research. PMID 30814678 DOI: 10.1038/S41422-019-0151-X  0.371
2019 Zhang K, Zhang H, Li S, Pintilie GD, Mou TC, Gao Y, Zhang Q, Bedem Hvd, Schmid MF, Au SWN, Chiu W. Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution. Proceedings of the National Academy of Sciences of the United States of America. 116: 6800-6805. DOI: 10.2210/Pdb6Nym/Pdb  0.356
2019 Lawson CL, Kryshtafovych A, Pintilie G, Berman HM, Chiu W. Evolving data standards for cryo electron microscopy Acta Crystallographica Section a Foundations and Advances. 75: a68-a68. DOI: 10.1107/S0108767319099318  0.324
2019 Chiu W, Pintilie G. Quantifying the resolvability in cryo-EM structures Acta Crystallographica Section A. 75. DOI: 10.1107/S0108767319096582  0.36
2019 Li Y, Zhou W, Li Y, Huang W, Zhang Z, Chen G, Wang H, Wu G, Rolston N, Vila R, Chiu W, Cui Y. Unravelling Degradation Mechanisms and Atomic Structure of Organic-Inorganic Halide Perovskites by Cryo-EM Joule. 3: 2854-2866. DOI: 10.1016/J.Joule.2019.08.016  0.356
2018 Dosey TL, Wang Z, Fan G, Zhang Z, Serysheva II, Chiu W, Wensel TG. Structures of TRPV2 in distinct conformations provide insight into role of the pore turret. Nature Structural & Molecular Biology. PMID 30598551 DOI: 10.1038/S41594-018-0168-8  0.723
2018 Michalska K, Zhang K, March ZM, Hatzos-Skintges C, Pintilie G, Bigelow L, Castellano LM, Miles LJ, Jackrel ME, Chuang E, Jedrzejczak R, Shorter J, Chiu W, Joachimiak A. Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events. Structure (London, England : 1993). PMID 30595457 DOI: 10.1016/J.Str.2018.11.001  0.329
2018 Qi X, Zhang F, Su Z, Jiang S, Han D, Ding B, Liu Y, Chiu W, Yin P, Yan H. Programming molecular topologies from single-stranded nucleic acids. Nature Communications. 9: 4579. PMID 30389935 DOI: 10.1038/S41467-018-07039-7  0.665
2018 Lawson CL, Chiu W. Comparing Cryo-EM Structures. Journal of Structural Biology. PMID 30321594 DOI: 10.1016/J.Jsb.2018.10.004  0.351
2018 Duyvesteyn HME, Kotecha A, Ginn HM, Hecksel CW, Beale EV, de Haas F, Evans G, Zhang P, Chiu W, Stuart DI. Machining protein microcrystals for structure determination by electron diffraction. Proceedings of the National Academy of Sciences of the United States of America. PMID 30171169 DOI: 10.1073/Pnas.1809978115  0.348
2018 Pintilie G, Chiu W. Assessment of Structural Features in Cryo-EM Density Maps using SSE and Side Chain Z-Scores. Journal of Structural Biology. PMID 30144506 DOI: 10.1016/J.Jsb.2018.08.015  0.303
2018 Dai W, Chen M, Myers C, Ludtke SJ, Montgomery Pettitt B, King JA, Schmid MF, Chiu W. Visualizing Individual RuBisCO and its Assembly into Carboxysomes in Marine Cyanobacteria by Cryo-Electron Tomography. Journal of Molecular Biology. PMID 30138616 DOI: 10.1016/J.Jmb.2018.08.013  0.6
2018 Heymann JB, Marabini R, Kazemi M, Sorzano COS, Holmdahl M, Mendez JH, Stagg SM, Jonic S, Palovcak E, Armache JP, Zhao J, Cheng Y, Pintilie G, Chiu W, Patwardhan A, et al. The First Single Particle Analysis Map Challenge: A Summary of the Assessments. Journal of Structural Biology. PMID 30114512 DOI: 10.1016/J.Jsb.2018.08.010  0.332
2018 Ge Z, Su Z, Simmons CR, Li J, Jiang S, Li W, Yang Y, Liu Y, Chiu W, Fan C, Yan H. Redox Engineering of Cytochrome c using DNA Nanostructure-Based Charged Encapsulation and Spatial Control. Acs Applied Materials & Interfaces. PMID 29939710 DOI: 10.1021/Acsami.8B07101  0.666
2018 Sun SY, Kaelber JT, Chen M, Dong X, Nematbakhsh Y, Shi J, Dougherty M, Lim CT, Schmid MF, Chiu W, He CY. Flagellum couples cell shape to motility in . Proceedings of the National Academy of Sciences of the United States of America. PMID 29891682 DOI: 10.1073/Pnas.1722618115  0.689
2018 Roh SH, Stam NJ, Hryc CF, Couoh-Cardel S, Pintilie G, Chiu W, Wilkens S. The 3.5-Å CryoEM Structure of Nanodisc-Reconstituted Yeast Vacuolar ATPase VProton Channel. Molecular Cell. PMID 29526695 DOI: 10.1016/J.Molcel.2018.02.006  0.733
2018 Su Z, Wu C, Shi L, Luthra P, Pintilie GD, Johnson B, Porter JR, Ge P, Chen M, Liu G, Frederick TE, Binning JM, Bowman GR, Zhou ZH, Basler CF, ... ... Chiu W, et al. Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly. Cell. 172: 966-978.e12. PMID 29474922 DOI: 10.1016/J.Cell.2018.02.009  0.694
2018 Zhang K, Keane SC, Su Z, Irobalieva RN, Chen M, Van V, Sciandra CA, Marchant J, Heng X, Schmid MF, Case DA, Ludtke SJ, Summers MF, Chiu W. Structure of the 30 kDa HIV-1 RNA Dimerization Signal by a Hybrid Cryo-EM, NMR, and Molecular Dynamics Approach. Structure (London, England : 1993). PMID 29398526 DOI: 10.1016/J.Str.2018.01.001  0.766
2018 Du D, Wang Z, Chiu W, Luisi BF. Purification of AcrAB-TolC Multidrug Efflux Pump for Cryo-EM Analysis. Methods in Molecular Biology (Clifton, N.J.). 1700: 71-81. PMID 29177826 DOI: 10.1007/978-1-4939-7454-2_5  0.705
2018 Miao J, Pryor A, Yang Y, Rana A, Gallagher-Jones M, Zhou J, Lo YH, Rodriguez JA, Chiu W. GENFIRE: from Precisely Localizing Single Atoms in Materials to High Resolution 3D Imaging of Cellular Structures Microscopy and Microanalysis. 24: 1446-1447. DOI: 10.1017/S1431927618007717  0.326
2017 Erasmus JH, Seymour RL, Kaelber JT, Kim DY, Leal G, Sherman MB, Frolov I, Chiu W, Weaver SC, Nasar F. Novel insect-specific Eilat virus-based chimeric vaccine candidates provide durable, mono- and multi-valent, single dose protection against lethal alphavirus challenge. Journal of Virology. PMID 29187545 DOI: 10.1128/Jvi.01274-17  0.693
2017 Liu Y, Lan X, Su Z, Zhou Y, Meyer T, Ke Y, Wang Q, Chiu W, Liu N, Zou S, Yan H. Programmable Supra-Assembly of DNA Surface Adapter for Tunable Chiral Directional Self-Assembly of Gold Nanorods. Angewandte Chemie (International Ed. in English). PMID 28971555 DOI: 10.1002/Anie.201709775  0.644
2017 Chen M, Dai W, Sun SY, Jonasch D, He CY, Schmid MF, Chiu W, Ludtke SJ. Convolutional neural networks for automated annotation of cellular cryo-electron tomograms. Nature Methods. PMID 28846087 DOI: 10.1038/Nmeth.4405  0.581
2017 Yi P, Wang Z, Feng Q, Chou CK, Pintilie GD, Shen H, Foulds CE, Fan G, Serysheva I, Ludtke SJ, Schmid MF, Hung MC, Chiu W, O'Malley BW. Structural and Functional Impacts of ER Coactivator Sequential Recruitment. Molecular Cell. 67: 733-743.e4. PMID 28844863 DOI: 10.1016/J.Molcel.2017.07.026  0.766
2017 Chiu W, Downing KH. Editorial overview: Cryo Electron Microscopy: Exciting advances in CryoEM Herald a new era in structural biology. Current Opinion in Structural Biology. PMID 28801059 DOI: 10.1016/J.Sbi.2017.07.006  0.348
2017 Kaelber JT, Hryc CF, Chiu W. Electron Cryomicroscopy of Viruses at Near-Atomic Resolutions. Annual Review of Virology. PMID 28715974 DOI: 10.1146/Annurev-Virology-101416-041921  0.762
2017 Roh SH, Hryc CF, Jeong HH, Fei X, Jakana J, Lorimer GH, Chiu W. Subunit conformational variation within individual GroEL oligomers resolved by Cryo-EM. Proceedings of the National Academy of Sciences of the United States of America. PMID 28710336 DOI: 10.1073/Pnas.1704725114  0.744
2017 Wang Z, Fan G, Hryc CF, Blaza JN, Serysheva II, Schmid MF, Chiu W, Luisi BF, Du D. An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump. Elife. 6. PMID 28355133 DOI: 10.7554/Elife.24905  0.71
2017 Hryc CF, Chen DH, Afonine PV, Jakana J, Wang Z, Haase-Pettingell C, Jiang W, Adams PD, King JA, Schmid MF, Chiu W. Accurate model annotation of a near-atomic resolution cryo-EM map. Proceedings of the National Academy of Sciences of the United States of America. PMID 28270620 DOI: 10.1073/Pnas.1621152114  0.748
2017 Wang Z, Fan G, Hryc CF, Blaza JN, Serysheva II, Schmid MF, Chiu W, Luisi BF, Du D. Author response: An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump Elife. DOI: 10.7554/Elife.24905.042  0.665
2017 Chen M, Dai W, Sun SY, Schmid MF, Chiu W, Ludtke SJ. Going Deeper in Cryo Electron Tomography with Neural Networks Microscopy and Microanalysis. 23: 814-815. DOI: 10.1017/S1431927617004731  0.548
2017 Chiu W. Optimization of a Cryo-EM Structural Model Representation Biophysical Journal. 112: 341a. DOI: 10.1016/J.Bpj.2016.11.1852  0.396
2017 Zhang H, Wang Z, Rong M, Pan Y, Chiu W, Zhou M. Novel Mechanism of Gating in the TrkH-TrkA Complex Biophysical Journal. 112: 21a-22a. DOI: 10.1016/J.Bpj.2016.11.150  0.727
2016 Erasmus JH, Auguste AJ, Kaelber JT, Luo H, Rossi SL, Fenton K, Leal G, Kim DY, Chiu W, Wang T, Frolov I, Nasar F, Weaver SC. A chikungunya fever vaccine utilizing an insect-specific virus platform. Nature Medicine. PMID 27991917 DOI: 10.1038/Nm.4253  0.699
2016 DiMaio F, Chiu W. Tools for Model Building and Optimization into Near-Atomic Resolution Electron Cryo-Microscopy Density Maps. Methods in Enzymology. 579: 255-76. PMID 27572730 DOI: 10.1016/Bs.Mie.2016.06.003  0.361
2016 Roh SH, Kasembeli MM, Galaz-Montoya JG, Chiu W, Tweardy DJ. Chaperonin TRiC/CCT Recognizes Fusion Oncoprotein AML1-ETO through Subunit-Specific Interactions. Biophysical Journal. 110: 2377-2385. PMID 27276256 DOI: 10.1016/J.Bpj.2016.04.045  0.712
2016 Veneziano R, Ratanalert S, Zhang K, Zhang F, Yan H, Chiu W, Bathe M. Designer nanoscale DNA assemblies programmed from the top down. Science (New York, N.Y.). PMID 27229143 DOI: 10.1126/Science.Aaf4388  0.306
2016 Hecksel CW, Darrow MC, Dai W, Galaz-Montoya JG, Chin JA, Mitchell PG, Chen S, Jakana J, Schmid MF, Chiu W. Quantifying Variability of Manual Annotation in Cryo-Electron Tomograms. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 1-10. PMID 27225525 DOI: 10.1017/S1431927616000799  0.307
2016 Galaz-Montoya JG, Hecksel CW, Baldwin PR, Wang E, Weaver SC, Schmid MF, Ludtke SJ, Chiu W. Alignment Algorithms and Per-Particle CTF Correction for Single Particle Cryo-Electron Tomography. Journal of Structural Biology. PMID 27016284 DOI: 10.1016/J.Jsb.2016.03.018  0.611
2016 Marabini R, Ludtke SJ, Murray SC, Chiu W, de la Rosa-Trevín JM, Patwardhan A, Heymann JB, Carazo JM. The Electron Microscopy eXchange (EMX) initiative. Journal of Structural Biology. 194: 156-63. PMID 26873784 DOI: 10.1016/J.Jsb.2016.02.008  0.618
2016 Galaz-Montoya JG, Hecksel CW, Chin J, Wang R, Lewis CW, Haemmerle M, Schmid MF, Ludtke SJ, Sood AK, Chiu W. Computational Tools to Improve Visualization by Cryo-Electron Tomography Biophysical Journal. 110: 159a. DOI: 10.1016/J.Bpj.2015.11.891  0.609
2016 Pintilie G, Chen D, King JA, Chiu W. Resolution and Probabilistic Structural Models of Subcomponents Derived from CryoEM Maps of Mature P22 Bacteriophage Biophysical Journal. 110: 158a. DOI: 10.1016/J.Bpj.2015.11.887  0.346
2016 Ratanalert S, Veneziano R, Zhang K, Pan K, Zhang F, Chiu W, Yan H, Bathe M. Structure-Based Design, Synthesis, and Characterization of Custom DNA Nanoparticles Biophysical Journal. 110: 565a. DOI: 10.1016/J.Bpj.2015.11.3025  0.362
2016 Dosey TL, Wang Z, Guizhen F, Serysheva II, Chiu W, Wensel TG. Structural Basis of TRPV2 Channel Gating Investigated with cryo-EM Biophysical Journal. 110: 25a. DOI: 10.1016/J.Bpj.2015.11.201  0.732
2016 Wang Z, Du D, Fan G, Serysheva II, Luisi BF, Chiu W. Structure of the AcrABZ-TolC Multidrug Efflux Pump in a Drug-Bound State Biophysical Journal. 110: 10a. DOI: 10.1016/J.Bpj.2015.11.108  0.74
2015 Pintilie G, Chen DH, Haase-Pettingell CA, King JA, Chiu W. Resolution and Probabilistic Models of Components in CryoEM Maps of Mature P22 Bacteriophage. Biophysical Journal. PMID 26743049 DOI: 10.1016/J.Bpj.2015.11.3522  0.364
2015 Roh SH, Kasembeli M, Galaz-Montoya JG, Trnka M, Lau WC, Burlingame A, Chiu W, Tweardy DJ. Chaperonin TRiC/CCT Modulates the Folding and Activity of Leukemogenic Fusion Oncoprotein AML1-ETO. The Journal of Biological Chemistry. PMID 26706127 DOI: 10.1074/Jbc.M115.684878  0.69
2015 Wang R, Stone RL, Kaelber JT, Rochat RH, Nick AM, Vijayan KV, Afshar-Kharghan V, Schmid MF, Dong JF, Sood AK, Chiu W. Electron cryotomography reveals ultrastructure alterations in platelets from patients with ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. 112: 14266-14271. PMID 26578771 DOI: 10.1073/Pnas.1518628112  0.68
2015 Lawson CL, Patwardhan A, Baker ML, Hryc C, Garcia ES, Hudson BP, Lagerstedt I, Ludtke SJ, Pintilie G, Sala R, Westbrook JD, Berman HM, Kleywegt GJ, Chiu W. EMDataBank unified data resource for 3DEM. Nucleic Acids Research. PMID 26578576 DOI: 10.1093/Nar/Gkv1126  0.614
2015 Roh SH, Kasembeli M, Bakthavatsalam D, Chiu W, Tweardy DJ. Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis. International Journal of Molecular Sciences. 16: 26706-20. PMID 26561808 DOI: 10.3390/Ijms161125975  0.696
2015 Irobalieva RN, Fogg JM, Catanese DJ, Sutthibutpong T, Chen M, Barker AK, Ludtke SJ, Harris SA, Schmid MF, Chiu W, Zechiedrich L. Erratum: Structural diversity of supercoiled DNA. Nature Communications. 6: 8851. PMID 26511109 DOI: 10.1038/Ncomms9851  0.536
2015 Fan G, Baker ML, Wang Z, Baker MR, Sinyagovskiy PA, Chiu W, Ludtke SJ, Serysheva II. Gating machinery of InsP3R channels revealed by electron cryomicroscopy. Nature. PMID 26458101 DOI: 10.1038/Nature15249  0.779
2015 Irobalieva RN, Fogg JM, Catanese DJ, Sutthibutpong T, Chen M, Barker AK, Ludtke SJ, Harris SA, Schmid MF, Chiu W, Zechiedrich L. Structural diversity of supercoiled DNA. Nature Communications. 6: 8440. PMID 26455586 DOI: 10.1038/Ncomms9440  0.563
2015 Lu J, Trnka MJ, Roh SH, Robinson PJ, Shiau C, Fujimori DG, Chiu W, Burlingame AL, Guan S. Improved Peak Detection and Deconvolution of Native Electrospray Mass Spectra from Large Protein Complexes. Journal of the American Society For Mass Spectrometry. PMID 26323614 DOI: 10.1007/S13361-015-1235-6  0.693
2015 Darrow MC, Sergeeva OA, Isas JM, Galaz-Montoya J, King JA, Langen R, Schmid MF, Chiu W. Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by Synthetic Chaperonin-like CCT5 Complex Explained by Cryo-electron Tomography. The Journal of Biological Chemistry. PMID 25995452 DOI: 10.1074/Jbc.M115.655373  0.312
2015 Marabini R, Carragher B, Chen S, Chen J, Cheng A, Downing KH, Frank J, Grassucci RA, Bernard Heymann J, Jiang W, Jonic S, Liao HY, Ludtke SJ, Patwari S, Piotrowski AL, ... ... Chiu W, et al. CTF Challenge: Result summary. Journal of Structural Biology. 190: 348-59. PMID 25913484 DOI: 10.1016/J.Jsb.2015.04.003  0.692
2015 Leung DW, Borek D, Luthra P, Binning JM, Anantpadma M, Liu G, Harvey IB, Su Z, Endlich-Frazier A, Pan J, Shabman RS, Chiu W, Davey RA, Otwinowski Z, Basler CF, et al. An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions. Cell Reports. 11: 376-89. PMID 25865894 DOI: 10.1016/J.Celrep.2015.03.034  0.651
2015 Du D, Voss J, Wang Z, Chiu W, Luisi BF. The pseudo-atomic structure of an RND-type tripartite multidrug efflux pump. Biological Chemistry. PMID 25803077 DOI: 10.1515/Hsz-2015-0118  0.705
2015 Yi P, Wang Z, Feng Q, Pintilie GD, Foulds CE, Lanz RB, Ludtke SJ, Schmid MF, Chiu W, O'Malley BW. Structure of a biologically active estrogen receptor-coactivator complex on DNA. Molecular Cell. 57: 1047-58. PMID 25728767 DOI: 10.1016/J.Molcel.2015.01.025  0.775
2015 Hong C, Pietilä MK, Fu CJ, Schmid MF, Bamford DH, Chiu W. Lemon-shaped halo archaeal virus His1 with uniform tail but variable capsid structure. Proceedings of the National Academy of Sciences of the United States of America. 112: 2449-54. PMID 25675521 DOI: 10.1073/Pnas.1425008112  0.341
2015 Auguste AJ, Kaelber JT, Fokam EB, Guzman H, Carrington CV, Erasmus JH, Kamgang B, Popov VL, Jakana J, Liu X, Wood TG, Widen SG, Vasilakis N, Tesh RB, Chiu W, et al. A newly isolated reovirus has the simplest genomic and structural organization of any reovirus. Journal of Virology. 89: 676-87. PMID 25355879 DOI: 10.1128/Jvi.02264-14  0.721
2015 Ludtke SJ, Fan G, Baker ML, Wang Z, Baker MR, Murray S, Synyagovsky PA, Chiu W, Serysheva II. IP3R1 - Assessing Map Interpretability at Near Atomic Resolution Microscopy and Microanalysis. 21: 543-544. DOI: 10.1017/S1431927615003517  0.758
2015 Baker ML, Chen M, Baldwin PR, Ludtke SJ, Chiu W. Modeling Protein Structure in Macromolecular Assemblies at Near Atomic Resolutions Microscopy and Microanalysis. 21: 541-542. DOI: 10.1017/S1431927615003505  0.616
2014 Hong C, Oksanen HM, Liu X, Jakana J, Bamford DH, Chiu W. A structural model of the genome packaging process in a membrane-containing double stranded DNA virus. Plos Biology. 12: e1002024. PMID 25514469 DOI: 10.1371/Journal.Pbio.1002024  0.344
2014 Dai W, Schmid MF, King JA, Chiu W. Identifying the assembly pathway of cyanophage inside the marine bacterium using electron cryo-tomography. Microbial Cell. 1: 45-47. PMID 25419524 DOI: 10.15698/Mic2014.01.125  0.356
2014 Dai W, Fu C, Khant HA, Ludtke SJ, Schmid MF, Chiu W. Zernike phase-contrast electron cryotomography applied to marine cyanobacteria infected with cyanophages. Nature Protocols. 9: 2630-42. PMID 25321408 DOI: 10.1038/Nprot.2014.176  0.608
2014 Guo F, Liu Z, Fang PA, Zhang Q, Wright ET, Wu W, Zhang C, Vago F, Ren Y, Jakana J, Chiu W, Serwer P, Jiang W. Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions. Proceedings of the National Academy of Sciences of the United States of America. 111: E4606-14. PMID 25313071 DOI: 10.1073/Pnas.1407020111  0.463
2014 Wang Z, Hryc CF, Bammes B, Afonine PV, Jakana J, Chen DH, Liu X, Baker ML, Kao C, Ludtke SJ, Schmid MF, Adams PD, Chiu W. An atomic model of brome mosaic virus using direct electron detection and real-space optimization. Nature Communications. 5: 4808. PMID 25185801 DOI: 10.1038/Ncomms5808  0.802
2014 Guo YR, Hryc CF, Jakana J, Jiang H, Wang D, Chiu W, Zhong W, Tao YJ. Crystal structure of a nematode-infecting virus. Proceedings of the National Academy of Sciences of the United States of America. 111: 12781-6. PMID 25136116 DOI: 10.1073/Pnas.1407122111  0.353
2014 Gipson P, Baker ML, Raytcheva D, Haase-Pettingell C, Piret J, King JA, Chiu W. Protruding knob-like proteins violate local symmetries in an icosahedral marine virus. Nature Communications. 5: 4278. PMID 24985522 DOI: 10.1038/Ncomms5278  0.364
2014 Rizzo AA, Suhanovsky MM, Baker ML, Fraser LC, Jones LM, Rempel DL, Gross ML, Chiu W, Alexandrescu AT, Teschke CM. Multiple functional roles of the accessory I-domain of bacteriophage P22 coat protein revealed by NMR structure and CryoEM modeling. Structure (London, England : 1993). 22: 830-41. PMID 24836025 DOI: 10.1016/J.Str.2014.04.003  0.302
2014 Kasembeli M, Lau WC, Roh SH, Eckols TK, Frydman J, Chiu W, Tweardy DJ. Modulation of STAT3 folding and function by TRiC/CCT chaperonin. Plos Biology. 12: e1001844. PMID 24756126 DOI: 10.1371/Journal.Pbio.1001844  0.691
2014 Du D, Wang Z, James NR, Voss JE, Klimont E, Ohene-Agyei T, Venter H, Chiu W, Luisi BF. Structure of the AcrAB-TolC multidrug efflux pump. Nature. 509: 512-5. PMID 24747401 DOI: 10.1038/Nature13205  0.709
2014 Chiu W, Crépin T, Ruigrok RW. Editorial overview: virus structure and function. Current Opinion in Virology. 5: viii-ix. PMID 24726158 DOI: 10.1016/J.Coviro.2014.03.003  0.375
2014 Rochat RH, Hecksel CW, Chiu W. Cryo-EM techniques to resolve the structure of HSV-1 capsid-associated components. Methods in Molecular Biology (Clifton, N.J.). 1144: 265-81. PMID 24671690 DOI: 10.1007/978-1-4939-0428-0_18  0.411
2014 Shahmoradian SH, Galiano MR, Wu C, Chen S, Rasband MN, Mobley WC, Chiu W. Preparation of primary neurons for visualizing neurites in a frozen-hydrated state using cryo-electron tomography. Journal of Visualized Experiments : Jove. e50783. PMID 24561719 DOI: 10.3791/50783  0.301
2014 Popova OB, Fan G, Baker MR, Jakana J, Chiu W, Ludtke SJ, Serysheva II. Cryo-EM Studies of RyR1 Channel in Detergent-Free Aqueous Environment Biophysical Journal. 106: 109a. DOI: 10.1016/J.Bpj.2013.11.668  0.613
2014 Wang Z, Hryc C, Bammes B, Afonine P, Jakana J, Chen D, liu x, Baker ML, Kao C, Ludtke SJ, Schmid MF, Adams P, Chiu W. CRYO-EM Atomic Model of Brome Mosaic Virus Derived from Direct Electron Detection Images and a Real-Space Model Optimization Protocol Biophysical Journal. 106: 600a. DOI: 10.1016/J.Bpj.2013.11.3321  0.804
2014 Hoersch D, Roh S, Chiu W, Kortemme T. Reprogramming an ATP-Driven Biological Machine into a Light-Gated Protein Nanocage Biophysical Journal. 106: 439a. DOI: 10.1016/J.Bpj.2013.11.2472  0.72
2013 Hoersch D, Roh SH, Chiu W, Kortemme T. Reprogramming an ATP-driven protein machine into a light-gated nanocage. Nature Nanotechnology. 8: 928-32. PMID 24270642 DOI: 10.1038/Nnano.2013.242  0.724
2013 Dai W, Fu C, Raytcheva D, Flanagan J, Khant HA, Liu X, Rochat RH, Haase-Pettingell C, Piret J, Ludtke SJ, Nagayama K, Schmid MF, King JA, Chiu W. Visualizing virus assembly intermediates inside marine cyanobacteria. Nature. 502: 707-10. PMID 24107993 DOI: 10.1038/Nature12604  0.592
2013 Wagner G, Chiu W. Exploring new limits in complex biological structures. Current Opinion in Structural Biology. 23: 704-6. PMID 24076042 DOI: 10.1016/J.Sbi.2013.09.003  0.301
2013 Shahmoradian SH, Galaz-Montoya JG, Schmid MF, Cong Y, Ma B, Spiess C, Frydman J, Ludtke SJ, Chiu W. TRiC's tricks inhibit huntingtin aggregation. Elife. 2: e00710. PMID 23853712 DOI: 10.7554/Elife.00710  0.604
2013 Baker ML, Hryc CF, Zhang Q, Wu W, Jakana J, Haase-Pettingell C, Afonine PV, Adams PD, King JA, Jiang W, Chiu W. Validated near-atomic resolution structure of bacteriophage epsilon15 derived from cryo-EM and modeling. Proceedings of the National Academy of Sciences of the United States of America. 110: 12301-6. PMID 23840063 DOI: 10.1073/Pnas.1309947110  0.522
2013 Chen DH, Madan D, Weaver J, Lin Z, Schröder GF, Chiu W, Rye HS. Visualizing GroEL/ES in the act of encapsulating a folding protein. Cell. 153: 1354-65. PMID 23746846 DOI: 10.1016/J.Cell.2013.04.052  0.344
2013 Murray SC, Flanagan J, Popova OB, Chiu W, Ludtke SJ, Serysheva II. Validation of cryo-EM structure of IP₃R1 channel. Structure (London, England : 1993). 21: 900-9. PMID 23707684 DOI: 10.1016/J.Str.2013.04.016  0.64
2013 Sergeeva OA, Chen B, Haase-Pettingell C, Ludtke SJ, Chiu W, King JA. Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers. The Journal of Biological Chemistry. 288: 17734-44. PMID 23612981 DOI: 10.1074/Jbc.M112.443929  0.578
2013 DiMaio F, Zhang J, Chiu W, Baker D. Cryo-EM model validation using independent map reconstructions. Protein Science : a Publication of the Protein Society. 22: 865-8. PMID 23592445 DOI: 10.1002/Pro.2267  0.336
2013 Zhang Q, Dai X, Cong Y, Zhang J, Chen DH, Dougherty MT, Wang J, Ludtke SJ, Schmid MF, Chiu W. Cryo-EM structure of a molluscan hemocyanin suggests its allosteric mechanism. Structure (London, England : 1993). 21: 604-13. PMID 23541894 DOI: 10.1016/J.Str.2013.02.018  0.6
2013 Rees I, Langley E, Chiu W, Ludtke SJ. EMEN2: an object oriented database and electronic lab notebook. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 19: 1-10. PMID 23360752 DOI: 10.1017/S1431927612014043  0.589
2012 Gilliam JC, Chang JT, Sandoval IM, Zhang Y, Li T, Pittler SJ, Chiu W, Wensel TG. Three-dimensional architecture of the rod sensory cilium and its disruption in retinal neurodegeneration. Cell. 151: 1029-41. PMID 23178122 DOI: 10.1016/J.Cell.2012.10.038  0.321
2012 Schmid MF, Hecksel CW, Rochat RH, Bhella D, Chiu W, Rixon FJ. A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions. Plos Pathogens. 8: e1002961. PMID 23055933 DOI: 10.1371/Journal.Ppat.1002961  0.329
2012 Baker ML, Baker MR, Hryc CF, Ju T, Chiu W. Gorgon and pathwalking: macromolecular modeling tools for subnanometer resolution density maps. Biopolymers. 97: 655-68. PMID 22696403 DOI: 10.1002/Bip.22065  0.419
2012 Ludtke SJ, Lawson CL, Kleywegt GJ, Berman H, Chiu W. The 2010 cryo-EM modeling challenge. Biopolymers. 97: 651-4. PMID 22696402 DOI: 10.1002/Bip.22081  0.549
2012 Leitner A, Joachimiak LA, Bracher A, Mönkemeyer L, Walzthoeni T, Chen B, Pechmann S, Holmes S, Cong Y, Ma B, Ludtke S, Chiu W, Hartl FU, Aebersold R, Frydman J. The molecular architecture of the eukaryotic chaperonin TRiC/CCT. Structure (London, England : 1993). 20: 814-25. PMID 22503819 DOI: 10.1016/J.Str.2012.03.007  0.627
2012 Ni P, Wang Z, Ma X, Das NC, Sokol P, Chiu W, Dragnea B, Hagan M, Kao CC. An examination of the electrostatic interactions between the N-terminal tail of the Brome Mosaic Virus coat protein and encapsidated RNAs. Journal of Molecular Biology. 419: 284-300. PMID 22472420 DOI: 10.1016/J.Jmb.2012.03.023  0.692
2012 Baker MR, Rees I, Ludtke SJ, Chiu W, Baker ML. Constructing and validating initial Cα models from subnanometer resolution density maps with pathwalking. Structure (London, England : 1993). 20: 450-63. PMID 22405004 DOI: 10.1016/J.Str.2012.01.008  0.624
2012 Fauerbach JA, Yushchenko DA, Shahmoradian SH, Chiu W, Jovin TM, Jares-Erijman EA. Supramolecular non-amyloid intermediates in the early stages of α-synuclein aggregation. Biophysical Journal. 102: 1127-36. PMID 22404935 DOI: 10.1016/J.Bpj.2012.01.051  0.307
2012 Henderson R, Sali A, Baker ML, Carragher B, Devkota B, Downing KH, Egelman EH, Feng Z, Frank J, Grigorieff N, Jiang W, Ludtke SJ, Medalia O, Penczek PA, Rosenthal PB, ... ... Chiu W, et al. Outcome of the first electron microscopy validation task force meeting. Structure (London, England : 1993). 20: 205-14. PMID 22325770 DOI: 10.1016/J.Str.2011.12.014  0.696
2012 Chang J, Liu X, Rochat RH, Baker ML, Chiu W. Reconstructing virus structures from nanometer to near-atomic resolutions with cryo-electron microscopy and tomography. Advances in Experimental Medicine and Biology. 726: 49-90. PMID 22297510 DOI: 10.1007/978-1-4614-0980-9_4  0.44
2012 Bammes BE, Rochat RH, Jakana J, Chen DH, Chiu W. Direct electron detection yields cryo-EM reconstructions at resolutions beyond 3/4 Nyquist frequency. Journal of Structural Biology. 177: 589-601. PMID 22285189 DOI: 10.1016/J.Jsb.2012.01.008  0.747
2012 Cong Y, Schröder GF, Meyer AS, Jakana J, Ma B, Dougherty MT, Schmid MF, Reissmann S, Levitt M, Ludtke SL, Frydman J, Chiu W. Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle. The Embo Journal. 31: 720-30. PMID 22045336 DOI: 10.1038/Emboj.2011.366  0.603
2012 Galaz J, Flanagan J, Schmid M, Chiu W, Ludtke S. Single Particle Tomography in EMAN2 Microscopy and Microanalysis. 18: 552-553. DOI: 10.1017/S1431927612004618  0.568
2012 Chiu W, Liu X, Murata K, Khant H, Rochat R, Nagayama K, Rixon F. Zernike Phase Contrast Cryo-Electron Microscopy of Virus Particles Microscopy and Microanalysis. 18: 462-463. DOI: 10.1017/S1431927612004163  0.328
2012 Koyfman AY, Schmid MF, Gheiratmand L, Fu CJ, Huang D, Khant HA, He CY, Chiu W. Structural Investigation of Molecular Components of T. Brucei Flagellum by Cryo Electron Tomography Biophysical Journal. 102: 393a. DOI: 10.1016/J.Bpj.2011.11.2149  0.334
2011 Hryc CF, Chen DH, Chiu W. Near-atomic-resolution cryo-EM for molecular virology. Current Opinion in Virology. 1: 110-7. PMID 21845206 DOI: 10.1016/J.Coviro.2011.05.019  0.425
2011 Zhang R, Hryc CF, Cong Y, Liu X, Jakana J, Gorchakov R, Baker ML, Weaver SC, Chiu W. 4.4 Ã… cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus. The Embo Journal. 30: 3854-63. PMID 21829169 DOI: 10.1038/Emboj.2011.261  0.447
2011 Ludtke SJ, Tran TP, Ngo QT, Moiseenkova-Bell VY, Chiu W, Serysheva II. Flexible architecture of IP3R1 by Cryo-EM. Structure (London, England : 1993). 19: 1192-9. PMID 21827954 DOI: 10.1016/J.Str.2011.05.003  0.631
2011 Kostyuchenko VA, Jakana J, Liu X, Haddow AD, Aung M, Weaver SC, Chiu W, Lok SM. The structure of barmah forest virus as revealed by cryo-electron microscopy at a 6-angstrom resolution has detailed transmembrane protein architecture and interactions. Journal of Virology. 85: 9327-33. PMID 21752915 DOI: 10.1128/Jvi.05015-11  0.308
2011 Koyfman AY, Schmid MF, Gheiratmand L, Fu CJ, Khant HA, Huang D, He CY, Chiu W. Structure of Trypanosoma brucei flagellum accounts for its bihelical motion. Proceedings of the National Academy of Sciences of the United States of America. 108: 11105-8. PMID 21690369 DOI: 10.1073/Pnas.1103634108  0.302
2011 Bammes BE, Rochat RH, Jakana J, Chiu W. Practical performance evaluation of a 10k × 10k CCD for electron cryo-microscopy. Journal of Structural Biology. 175: 384-93. PMID 21619932 DOI: 10.1016/J.Jsb.2011.05.012  0.735
2011 Zhang J, Ma B, DiMaio F, Douglas NR, Joachimiak LA, Baker D, Frydman J, Levitt M, Chiu W. Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure. Structure (London, England : 1993). 19: 633-9. PMID 21565698 DOI: 10.1016/J.Str.2011.03.005  0.355
2011 Baker ML, Abeysinghe SS, Schuh S, Coleman RA, Abrams A, Marsh MP, Hryc CF, Ruths T, Chiu W, Ju T. Modeling protein structure at near atomic resolutions with Gorgon. Journal of Structural Biology. 174: 360-73. PMID 21296162 DOI: 10.1016/J.Jsb.2011.01.015  0.405
2011 Chen DH, Baker ML, Hryc CF, DiMaio F, Jakana J, Wu W, Dougherty M, Haase-Pettingell C, Schmid MF, Jiang W, Baker D, King JA, Chiu W. Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus. Proceedings of the National Academy of Sciences of the United States of America. 108: 1355-60. PMID 21220301 DOI: 10.1073/Pnas.1015739108  0.497
2011 Ludtke SJ, Lawson CL, Kleywegt GJ, Berman HM, Chiu W. Workshop on the validation and modeling of electron cryo-microscopy structures of biological nanomachines. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 369-73. PMID 21121065 DOI: 10.1142/9789814335058_0039  0.612
2011 Rochat RH, Liu X, Murata K, Nagayama K, Rixon FJ, Chiu W. Seeing the Portal in Herpes Simplex Virus Type 1 B Capsids Journal of Virology. 85: 1871-1874. PMID 21106752 DOI: 10.1128/Jvi.01663-10  0.35
2011 Knee KM, Goulet DR, Zhang J, Chen B, Chiu W, King JA. The group II chaperonin Mm-Cpn binds and refolds human γD crystallin. Protein Science : a Publication of the Protein Society. 20: 30-41. PMID 20981710 DOI: 10.1002/Pro.531  0.303
2011 Lawson CL, Baker ML, Best C, Bi C, Dougherty M, Feng P, van Ginkel G, Devkota B, Lagerstedt I, Ludtke SJ, Newman RH, Oldfield TJ, Rees I, Sahni G, Sala R, ... ... Chiu W, et al. EMDataBank.org: unified data resource for CryoEM. Nucleic Acids Research. 39: D456-64. PMID 20935055 DOI: 10.1093/Nar/Gkq880  0.626
2011 Gilliam JC, Chang JT, Chiu W, Wensel TG. Electron Cryo-Tomography of Cilia-Associated Structures of Rod Photoreceptors Biophysical Journal. 100: 338a. DOI: 10.1016/J.Bpj.2010.12.2049  0.359
2010 Baird NJ, Ludtke SJ, Khant H, Chiu W, Pan T, Sosnick TR. Discrete structure of an RNA folding intermediate revealed by cryo-electron microscopy. Journal of the American Chemical Society. 132: 16352-3. PMID 21038867 DOI: 10.1021/Ja107492B  0.634
2010 Miyazaki Y, Irobalieva RN, Tolbert BS, Smalls-Mantey A, Iyalla K, Loeliger K, D'Souza V, Khant H, Schmid MF, Garcia EL, Telesnitsky A, Chiu W, Summers MF. Structure of a conserved retroviral RNA packaging element by NMR spectroscopy and cryo-electron tomography. Journal of Molecular Biology. 404: 751-72. PMID 20933521 DOI: 10.1016/J.Jmb.2010.09.009  0.314
2010 Baker ML, Zhang J, Ludtke SJ, Chiu W. Cryo-EM of macromolecular assemblies at near-atomic resolution. Nature Protocols. 5: 1697-708. PMID 20885381 DOI: 10.1038/Nprot.2010.126  0.625
2010 Chang JT, Schmid MF, Haase-Pettingell C, Weigele PR, King JA, Chiu W. Visualizing the structural changes of bacteriophage Epsilon15 and its Salmonella host during infection. Journal of Molecular Biology. 402: 731-40. PMID 20709082 DOI: 10.1016/J.Jmb.2010.07.058  0.323
2010 Murata K, Liu X, Danev R, Jakana J, Schmid MF, King J, Nagayama K, Chiu W. Zernike phase contrast cryo-electron microscopy and tomography for structure determination at nanometer and subnanometer resolutions. Structure (London, England : 1993). 18: 903-12. PMID 20696391 DOI: 10.1016/J.Str.2010.06.006  0.401
2010 Liu X, Zhang Q, Murata K, Baker ML, Sullivan MB, Fu C, Dougherty MT, Schmid MF, Osburne MS, Chisholm SW, Chiu W. Structural changes in a marine podovirus associated with release of its genome into Prochlorococcus. Nature Structural & Molecular Biology. 17: 830-6. PMID 20543830 DOI: 10.1038/Nsmb.1823  0.362
2010 Saha M, Levitt M, Chiu W. MOTIF-EM: an automated computational tool for identifying conserved regions in CryoEM structures. Bioinformatics (Oxford, England). 26: i301-9. PMID 20529921 DOI: 10.1093/Bioinformatics/Btq195  0.359
2010 Nakamura N, Shimizu Y, Shinkawa T, Nakata M, Bammes B, Zhang J, Chiu W. Automated specimen search in cryo-TEM observation with DIFF-defocus imaging. Journal of Electron Microscopy. 59: 299-310. PMID 20356853 DOI: 10.1093/Jmicro/Dfq009  0.735
2010 Pintilie GD, Zhang J, Goddard TD, Chiu W, Gossard DC. Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions. Journal of Structural Biology. 170: 427-38. PMID 20338243 DOI: 10.1016/J.Jsb.2010.03.007  0.336
2010 Cong Y, Baker ML, Jakana J, Woolford D, Miller EJ, Reissmann S, Kumar RN, Redding-Johanson AM, Batth TS, Mukhopadhyay A, Ludtke SJ, Frydman J, Chiu W. 4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement. Proceedings of the National Academy of Sciences of the United States of America. 107: 4967-72. PMID 20194787 DOI: 10.1073/Pnas.0913774107  0.631
2010 Zhang J, Baker ML, Schröder GF, Douglas NR, Reissmann S, Jakana J, Dougherty M, Fu CJ, Levitt M, Ludtke SJ, Frydman J, Chiu W. Mechanism of folding chamber closure in a group II chaperonin. Nature. 463: 379-83. PMID 20090755 DOI: 10.1038/Nature08701  0.633
2010 Ren G, Rudenko G, Ludtke SJ, Deisenhofer J, Chiu W, Pownall HJ. Model of human low-density lipoprotein and bound receptor based on cryoEM. Proceedings of the National Academy of Sciences of the United States of America. 107: 1059-64. PMID 20080547 DOI: 10.1073/Pnas.0908004107  0.692
2010 Bammes BE, Jakana J, Schmid MF, Chiu W. Radiation damage effects at four specimen temperatures from 4 to 100 K. Journal of Structural Biology. 169: 331-41. PMID 19903530 DOI: 10.1016/J.Jsb.2009.11.001  0.707
2010 Schmid M, Chiu W, Bhella D, Rixon F. Cryo-Electron Tomography Reveals Tegument Density at the Portal Vertex of the HSV-1 Virion Microscopy and Microanalysis. 16: 1100-1101. DOI: 10.1017/S1431927610059465  0.307
2010 Murata K, Liu X, Danev R, Jakana J, Khant H, Schmid M, Nagayama K, Chiu W. Zernike Phase Contrast Cryo-EM for Biological Structure Determination Microscopy and Microanalysis. 16: 544-545. DOI: 10.1017/S1431927610057107  0.309
2010 Ludtke SJ, Tran TP, Ngo QT, Moiseenkova-Bell VY, Maxwell JT, Mignery GA, Chiu W, Serysheva II. Visualizing Alpha Helices in the Transmembrane Region of IP3R1 Calcium Release Channel by Single Particle Electron Cryomicroscopy Biophysical Journal. 98: 513a. DOI: 10.1016/J.Bpj.2009.12.2791  0.618
2010 Ren G, Rudenko G, Ludtke SJ, Deisenhofer J, Pownall HJ, Chiu W. The Molecular Architecture of Human Low Density Lipoprotein and Bound Receptor Revealed by Electron Cryo-Microscopy Biophysical Journal. 98: 384a-385a. DOI: 10.1016/J.Bpj.2009.12.2070  0.702
2010 Schmid MF, Chiu W, Bhella D, Rixon F. A Uniique Density at the Portal Vertex of HSV Virions Revealed by Asymmetric Averaging of Subtomograms Biophysical Journal. 98: 383a. DOI: 10.1016/J.Bpj.2009.12.2063  0.356
2010 Koyfman AY, Schmid MF, Gheiratmand L, Khant HA, Fu CJ, He CY, Chiu W. The Trypanosoma Brucei Flagellum Reveals Unique and Dynamic Structures of a Nanomachine Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.2062  0.349
2010 Zhang J, Baker ML, Schroeder G, Douglas NR, Jakana J, Fu CJ, Levitt M, Ludtke SJ, Frydman J, Chiu W. Rocking Motion of a Protein-Folding Nano-Machine Revealed By Single-Particle Cryo-Em Biophysical Journal. 98: 33a. DOI: 10.1016/J.Bpj.2009.12.192  0.607
2010 Cong Y, Baker M, Jakana J, Woolford D, Reissmann S, Ludtke SJ, Frydman J, Chiu W. 4.0 Å Cryo-EM Structure of the Mammalian Chaperonin: TRiC/CCT Biophysical Journal. 98: 222a-223a. DOI: 10.1016/J.Bpj.2009.12.1202  0.649
2010 Baker ML, Marsh MP, Chiu W. Electron Cryomicroscopy of Molecular Nanomachines and Cells Nanotechnology. 89-111. DOI: 10.1002/9783527628155.Nanotech052  0.401
2009 DiMaio F, Tyka MD, Baker ML, Chiu W, Baker D. Refinement of protein structures into low-resolution density maps using rosetta. Journal of Molecular Biology. 392: 181-90. PMID 19596339 DOI: 10.1016/J.Jmb.2009.07.008  0.351
2009 Cong Y, Zhang Q, Woolford D, Schweikardt T, Khant H, Dougherty M, Ludtke SJ, Chiu W, Decker H. Structural mechanism of SDS-induced enzyme activity of scorpion hemocyanin revealed by electron cryomicroscopy. Structure (London, England : 1993). 17: 749-58. PMID 19446530 DOI: 10.1016/J.Str.2009.03.005  0.599
2009 Zhang R, Hu X, Khant H, Ludtke SJ, Chiu W, Schmid MF, Frieden C, Lee JM. Interprotofilament interactions between alzheimer's aβ 1-42 peptides in amyloid fibrils revealed by cryoEM Proceedings of the National Academy of Sciences of the United States of America. 106: 4653-4658. PMID 19264960 DOI: 10.1073/Pnas.0901085106  0.566
2009 Yang C, Jiang W, Chen D, Adiga U, Ng EG, Chiu W. Estimating contrast transfer function and associated parameters by constrained non-linear optimization Journal of Microscopy. 233: 391-403. PMID 19250460 DOI: 10.1111/J.1365-2818.2009.03137.X  0.433
2009 Zhang J, Nakamura N, Shimizu Y, Liang N, Liu X, Jakana J, Marsh MP, Booth CR, Shinkawa T, Nakata M, Chiu W. JADAS: a customizable automated data acquisition system and its application to ice-embedded single particles. Journal of Structural Biology. 165: 1-9. PMID 18926912 DOI: 10.1016/J.Jsb.2008.09.006  0.543
2009 Ludtke S, Schmid M, Chiu W. Extending the Limits of Single Particle Reconstruction Microscopy and Microanalysis. 15: 566-567. DOI: 10.1017/S1431927609098225  0.575
2009 Ngo QT, Maxwell JT, Mignery GA, Chiu W, Ludtke SJ, Serysheva II. Electron Cryomicroscopy of IP3R1 Calcium Release Channel Biophysical Journal. 96: 96a. DOI: 10.1016/J.Bpj.2008.12.406  0.626
2008 Serysheva II, Ludtke SJ, Baker ML, Cong Y, Topf M, Eramian D, Sali A, Hamilton SL, Chiu W. Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel. Proceedings of the National Academy of Sciences of the United States of America. 105: 9610-5. PMID 18621707 DOI: 10.1073/Pnas.0803189105  0.598
2008 Chen DH, Luke K, Zhang J, Chiu W, Wittung-Stafshede P. Location and flexibility of the unique C-terminal tail of Aquifex aeolicus co-chaperonin protein 10 as derived by cryo-electron microscopy and biophysical techniques. Journal of Molecular Biology. 381: 707-17. PMID 18588898 DOI: 10.1016/J.Jmb.2008.06.021  0.421
2008 Booth CR, Meyer AS, Cong Y, Topf M, Sali A, Ludtke SJ, Chiu W, Frydman J. Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT. Nature Structural & Molecular Biology. 15: 746-53. PMID 18536725 DOI: 10.1038/Nsmb.1436  0.693
2008 Chen DH, Jakana J, Liu X, Schmid MF, Chiu W. Achievable resolution from images of biological specimens acquired from a 4k x 4k CCD camera in a 300-kV electron cryomicroscope. Journal of Structural Biology. 163: 45-52. PMID 18514542 DOI: 10.1016/J.Jsb.2008.04.001  0.353
2008 Ludtke SJ, Baker ML, Chen DH, Song JL, Chuang DT, Chiu W. De novo backbone trace of GroEL from single particle electron cryomicroscopy. Structure (London, England : 1993). 16: 441-8. PMID 18334219 DOI: 10.1016/J.Str.2008.02.007  0.653
2008 Jiang W, Baker ML, Jakana J, Weigele PR, King J, Chiu W. Backbone structure of the infectious epsilon15 virus capsid revealed by electron cryomicroscopy. Nature. 451: 1130-4. PMID 18305544 DOI: 10.1038/Nature06665  0.532
2008 Topf M, Lasker K, Webb B, Wolfson H, Chiu W, Sali A. Protein structure fitting and refinement guided by cryo-EM density. Structure (London, England : 1993). 16: 295-307. PMID 18275820 DOI: 10.1016/J.Str.2007.11.016  0.384
2008 Cong Y, Topf M, Sali A, Matsudaira P, Dougherty M, Chiu W, Schmid MF. Crystallographic conformers of actin in a biologically active bundle of filaments. Journal of Molecular Biology. 375: 331-6. PMID 18022194 DOI: 10.1016/J.Jmb.2007.10.027  0.303
2008 Jiang W, Baker M, Jakata J, Weigele P, King J, Chiu W. Backbone structure of the infectious Epsilon15 virus capsid revealed by electron cryomicroscopy Acta Crystallographica Section a Foundations of Crystallography. 64: C46-C46. DOI: 10.1107/S0108767308098528  0.477
2007 Marsh MP, Chang JT, Booth CR, Liang NL, Schmid MF, Chiu W. Modular software platform for low-dose electron microscopy and tomography. Journal of Microscopy. 228: 384-9. PMID 18045333 DOI: 10.1111/J.1365-2818.2007.01856.X  0.528
2007 Chiu W, Moffat K. Biophysical methods: structure, dynamics and gorgeous images. Current Opinion in Structural Biology. 17: 546-8. PMID 17959374 DOI: 10.1016/J.Sbi.2007.09.008  0.3
2007 Liu X, Jiang W, Jakana J, Chiu W. Averaging tens to hundreds of icosahedral particle images to resolve protein secondary structure elements using a Multi-Path Simulated Annealing optimization algorithm. Journal of Structural Biology. 160: 11-27. PMID 17698370 DOI: 10.1016/J.Jsb.2007.06.009  0.448
2007 Jiang W, Chiu W. Cryoelectron microscopy of icosahedral virus particles. Methods in Molecular Biology (Clifton, N.J.). 369: 345-63. PMID 17656759 DOI: 10.1007/978-1-59745-294-6_17  0.512
2007 Reissmann S, Parnot C, Booth CR, Chiu W, Frydman J. Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins. Nature Structural & Molecular Biology. 14: 432-40. PMID 17460696 DOI: 10.1038/Nsmb1236  0.501
2007 Johnson JE, Chiu W. DNA packaging and delivery machines in tailed bacteriophages. Current Opinion in Structural Biology. 17: 237-43. PMID 17395453 DOI: 10.1016/J.Sbi.2007.03.011  0.345
2007 Pope WH, Weigele PR, Chang J, Pedulla ML, Ford ME, Houtz JM, Jiang W, Chiu W, Hatfull GF, Hendrix RW, King J. Genome sequence, structural proteins, and capsid organization of the cyanophage Syn5: a "horned" bacteriophage of marine synechococcus. Journal of Molecular Biology. 368: 966-81. PMID 17383677 DOI: 10.1016/J.Jmb.2007.02.046  0.438
2007 Serysheva II, Chiu W, Ludtke SJ. Single-particle electron cryomicroscopy of the ion channels in the excitation-contraction coupling junction. Methods in Cell Biology. 79: 407-35. PMID 17327167 DOI: 10.1016/S0091-679X(06)79016-1  0.624
2007 Baker ML, Ju T, Chiu W. Identification of secondary structure elements in intermediate-resolution density maps. Structure (London, England : 1993). 15: 7-19. PMID 17223528 DOI: 10.1016/J.Str.2006.11.008  0.365
2007 Ludtke S, Baker M, Chen D, Song J, Chuang D, Chiu W. Backbone Trace of GroEL from a 4 A Resolution Single Particle Reconstruction Microscopy and Microanalysis. 13. DOI: 10.1017/S1431927607078178  0.589
2007 Serysheva I, Ludtke S, Baker M, Cong Y, Topf M, Sali A, Hamilton S, Chiu W. Single Particle Cryo-EM of RyR1 Channel at Subnanometer Resolution Microscopy and Microanalysis. 13. DOI: 10.1017/S1431927607071401  0.58
2006 Chang JT, Schmid MF, Rixon FJ, Chiu W. Electron cryotomography reveals the portal in the herpesvirus capsid. Journal of Virology. 81: 2065-8. PMID 17151101 DOI: 10.1128/Jvi.02053-06  0.346
2006 Chen DH, Song JL, Chuang DT, Chiu W, Ludtke SJ. An expanded conformation of single-ring GroEL-GroES complex encapsulates an 86 kDa substrate. Structure (London, England : 1993). 14: 1711-22. PMID 17098196 DOI: 10.1016/J.Str.2006.09.010  0.592
2006 Baker ML, Jiang W, Wedemeyer WJ, Rixon FJ, Baker D, Chiu W. Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density. Plos Computational Biology. 2: e146. PMID 17069457 DOI: 10.1371/Journal.Pcbi.0020146  0.502
2006 Booth CR, Jakana J, Chiu W. Assessing the capabilities of a 4kx4k CCD camera for electron cryo-microscopy at 300kV. Journal of Structural Biology. 156: 556-63. PMID 17067819 DOI: 10.1016/J.Jsb.2006.08.019  0.522
2006 Schmid MF, Paredes AM, Khant HA, Soyer F, Aldrich HC, Chiu W, Shively JM. Structure of Halothiobacillus neapolitanus carboxysomes by cryo-electron tomography. Journal of Molecular Biology. 364: 526-35. PMID 17028023 DOI: 10.1016/J.Jmb.2006.09.024  0.365
2006 Marsh MP, Campos SK, Baker ML, Chen CY, Chiu W, Barry MA. Cryoelectron microscopy of protein IX-modified adenoviruses suggests a new position for the C terminus of protein IX. Journal of Virology. 80: 11881-6. PMID 16987967 DOI: 10.1128/Jvi.01471-06  0.302
2006 Berman HM, Burley SK, Chiu W, Sali A, Adzhubei A, Bourne PE, Bryant SH, Dunbrack RL, Fidelis K, Frank J, Godzik A, Henrick K, Joachimiak A, Heymann B, Jones D, et al. Outcome of a Workshop on Archiving Structural Models of Biological Macromolecules Structure. 14: 1211-1217. PMID 16955948 DOI: 10.1016/J.Str.2006.06.005  0.458
2006 Baker ML, Yu Z, Chiu W, Bajaj C. Automated segmentation of molecular subunits in electron cryomicroscopy density maps. Journal of Structural Biology. 156: 432-41. PMID 16908194 DOI: 10.1016/J.Jsb.2006.05.013  0.325
2006 Chang J, Weigele P, King J, Chiu W, Jiang W. Cryo-EM asymmetric reconstruction of bacteriophage P22 reveals organization of its DNA packaging and infecting machinery. Structure (London, England : 1993). 14: 1073-82. PMID 16730179 DOI: 10.1016/J.Str.2006.05.007  0.451
2006 Araç D, Chen X, Khant HA, Ubach J, Ludtke SJ, Kikkawa M, Johnson AE, Chiu W, Südhof TC, Rizo J. Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nature Structural & Molecular Biology. 13: 209-17. PMID 16491093 DOI: 10.1038/Nsmb1056  0.548
2006 Topf M, Baker ML, Marti-Renom MA, Chiu W, Sali A. Refinement of protein structures by iterative comparative modeling and cryoEM density fitting Journal of Molecular Biology. 357: 1655-1668. PMID 16490207 DOI: 10.1016/J.Jmb.2006.01.062  0.376
2006 Chiu W, Baker ML, Almo SC. Structural biology of cellular machines Trends in Cell Biology. 16: 144-150. PMID 16459078 DOI: 10.1016/J.Tcb.2006.01.002  0.363
2006 Jiang W, Chang J, Jakana J, Weigele P, King J, Chiu W. Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatus Nature. 439: 612-616. PMID 16452981 DOI: 10.1038/Nature04487  0.503
2006 Chiu W. Electron diffraction of protein crystals International Tables For Crystallography. 423-427. DOI: 10.1107/97809553602060000699  0.348
2006 Khant H, Ludtke S, Chiu W. Automated Data Quality Assessment in Electron Cryomicroscopy Microscopy and Microanalysis. 12: 1108-1109. DOI: 10.1017/S1431927606068644  0.567
2006 Tu H, Chiu W, Mann D, Ludtke S. EMEN2: A Flexible & Mineable Data/Metadata Archival System for Cryo-EM Microscopy and Microanalysis. 12: 1098-1099. DOI: 10.1017/S1431927606067663  0.553
2005 Passmore LA, Booth CR, Vénien-Bryan C, Ludtke SJ, Fioretto C, Johnson LN, Chiu W, Barford D. Structural analysis of the anaphase-promoting complex reveals multiple active sites and insights into polyubiquitylation. Molecular Cell. 20: 855-66. PMID 16364911 DOI: 10.1016/J.Molcel.2005.11.003  0.678
2005 Baker ML, Jiang W, Rixon FJ, Chiu W. Common ancestry of herpesviruses and tailed DNA bacteriophages Journal of Virology. 79: 14967-14970. PMID 16282496 DOI: 10.1128/Jvi.79.23.14967-14970.2005  0.437
2005 Cong Y, Jiang W, Birmanns S, Zhou ZH, Chiu W, Wriggers W. Fast rotational matching of single-particle images. Journal of Structural Biology. 152: 104-12. PMID 16236526 DOI: 10.1016/J.Jsb.2005.08.006  0.449
2005 Ludtke SJ, Serysheva II, Hamilton SL, Chiu W. The pore structure of the closed RyR1 channel. Structure (London, England : 1993). 13: 1203-11. PMID 16084392 DOI: 10.1016/J.Str.2005.06.005  0.596
2005 Sitharaman B, Kissell KR, Hartman KB, Tran LA, Baikalov A, Rusakova I, Sun Y, Khant HA, Ludtke SJ, Chiu W, Laus S, Tóth E, Helm L, Merbach AE, Wilson LJ. Superparamagnetic gadonanotubes are high-performance MRI contrast agents. Chemical Communications (Cambridge, England). 3915-7. PMID 16075070 DOI: 10.1039/B504435A  0.531
2005 Chiu W, Baker ML, Jiang W, Dougherty M, Schmid MF. Electron cryomicroscopy of biological machines at subnanometer resolution. Structure (London, England : 1993). 13: 363-72. PMID 15766537 DOI: 10.1016/J.Str.2004.12.016  0.472
2005 Topf M, Baker ML, John B, Chiu W, Sali A. Structural characterization of components of protein assemblies by comparative modeling and electron cryo-microscopy Journal of Structural Biology. 149: 191-203. PMID 15681235 DOI: 10.1016/J.Jsb.2004.11.004  0.367
2005 Serysheva II, Hamilton SL, Chiu W, Ludtke SJ. Structure of Ca2+ release channel at 14 A resolution. Journal of Molecular Biology. 345: 427-31. PMID 15581887 DOI: 10.1016/J.Jmb.2004.10.073  0.633
2005 Marsh MP, Chang J, Chen J, Lopez J, Chiu W. The 3-Dimensional Architecture of Platelets in the Native State by Electron Cryotomography. Blood. 106: 1658-1658. DOI: 10.1182/Blood.V106.11.1658.1658  0.345
2005 Sali A, Topf M, Baker ML, Chiu W. Structure of protein assemblies by comparative modeling and electron microscopy Acta Crystallographica Section a Foundations of Crystallography. 61: c3-c3. DOI: 10.1107/S0108767305099897  0.393
2005 Schmid MF, Sherman MB, Matsudaira P, Chiu W. Structure of the Acrosomal Bundle, a Biological Machine, at 9.5 Â Resolution Microscopy and Microanalysis. 11. DOI: 10.1107/S0108767305097138  0.325
2005 Chiu W, Jiang W, Chang J, Jakana J, Weigele P, King J. Electron cryomicroscopy of epsilon 15 phage Acta Crystallographica Section a Foundations of Crystallography. 61: c455-c455. DOI: 10.1107/S0108767305080931  0.333
2005 Chiu W. Electron Cryomicroscopy of Cellular Machines at Subnanometer Resolution Microscopy and Microanalysis. 11. DOI: 10.1017/S1431927605509723  0.302
2005 Jakana J, Chiu W. Recording Subnanometer Resolution Images of Ice-Embedded Particles with a 4K CCD Camera in a 300 kV Electron Cryomicroscope Microscopy and Microanalysis. 11: 1054-1055. DOI: 10.1017/S143192760550391X  0.317
2005 Ludtke SJ, Booth CR, Serysheva II, Chen D, Chiu W. Single Particle Reconstructions at Subnanometer Resolution from a JEOL 2010F and a 4k x 4k Gatan CCD Camera Microscopy and Microanalysis. 11. DOI: 10.1017/S143192760550388X  0.642
2005 Chen D, Song J, Chuang DT, Chiu W, Ludtke S. Novel Conformation of Single Ring GroEL-GroES Suitable for Encapsulation of an 86 kDa Assembly Intermediate as Visualized by Electron Cryomicroscopy Microscopy and Microanalysis. 11. DOI: 10.1017/S1431927605502393  0.589
2005 Nakamura N, Moriya T, Shinkawa T, Booth CR, Chiu W. A Programmable TEM Image Collection System Microscopy and Microanalysis. 11. DOI: 10.1017/S1431927605500801  0.473
2005 Sali A, Chiu W. Macromolecular assemblies highlighted Structure. 13: 339-341. DOI: 10.1016/J.Str.2005.02.010  0.339
2004 Schmid MF, Sherman MB, Matsudaira P, Chiu W. Structure of the acrosomal bundle Nature. 431: 104-107. PMID 15343340 DOI: 10.1038/Nature02881  0.327
2004 Mao Y, Vyas NK, Vyas MN, Chen DH, Ludtke SJ, Chiu W, Quiocho FA. Structure of the bifunctional and Golgi-associated formiminotransferase cyclodeaminase octamer. The Embo Journal. 23: 2963-71. PMID 15272307 DOI: 10.1038/Sj.Emboj.7600327  0.61
2004 Ludtke SJ, Chen DH, Song JL, Chuang DT, Chiu W. Seeing GroEL at 6 A resolution by single particle electron cryomicroscopy. Structure (London, England : 1993). 12: 1129-36. PMID 15242589 DOI: 10.1016/J.Str.2004.05.006  0.644
2004 Booth CR, Jiang W, Baker ML, Zhou ZH, Ludtke SJ, Chiu W. A 9 angstroms single particle reconstruction from CCD captured images on a 200 kV electron cryomicroscope. Journal of Structural Biology. 147: 116-27. PMID 15193640 DOI: 10.1016/J.Jsb.2004.02.004  0.744
2004 Chen C, Ko Y, Delannoy M, Ludtke SJ, Chiu W, Pedersen PL. Mitochondrial ATP synthasome: three-dimensional structure by electron microscopy of the ATP synthase in complex formation with carriers for Pi and ADP/ATP. The Journal of Biological Chemistry. 279: 31761-8. PMID 15166242 DOI: 10.1074/Jbc.M401353200  0.596
2004 Brink J, Ludtke SJ, Kong Y, Wakil SJ, Ma J, Chiu W. Experimental verification of conformational variation of human fatty acid synthase as predicted by normal mode analysis. Structure (London, England : 1993). 12: 185-91. PMID 14962379 DOI: 10.1016/J.Str.2004.01.015  0.633
2004 Ludtke SJ, Chen D, Song J, Chuang DT, Chiu W. GroEL Structure at 6 Å Resolution Using Electron Cryomicroscopy and EMAN Microscopy and Microanalysis. 10: 1494-1495. DOI: 10.1017/S1431927604883296  0.622
2004 Kang S, Jiang W, Li Z, Zhang Z, Baker ML, Chiu W, Prevelige PE. Cryo-EM and mass spectrometry based investigations of viral capsid morphogenesis Microscopy and Microanalysis. 10: 226-227. DOI: 10.1017/S143192760488303X  0.374
2003 Ludtke SJ, Nason L, Tu H, Peng L, Chiu W. Object oriented database and electronic notebook for transmission electron microscopy. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 9: 556-65. PMID 14750990 DOI: 10.1017/S1431927603030575  0.595
2003 Jiang W, Baker ML, Wu Q, Bajaj C, Chiu W. Applications of a bilateral denoising filter in biological electron microscopy. Journal of Structural Biology. 144: 114-22. PMID 14643214 DOI: 10.1016/J.Jsb.2003.09.028  0.431
2003 Ludtke SJ, Chiu W. Focal pair merging for contrast enhancement of single particles Journal of Structural Biology. 144: 73-78. PMID 14643210 DOI: 10.1016/J.Jsb.2003.10.012  0.596
2003 Lee S, Sowa ME, Watanabe YH, Sigler PB, Chiu W, Yoshida M, Tsai FT. The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state. Cell. 115: 229-40. PMID 14567920 DOI: 10.1016/S0092-8674(03)00807-9  0.35
2003 Rixon FJ, Chiu W. Studying large viruses Advances in Protein Chemistry. 64: 379-408. PMID 13677054 DOI: 10.1016/S0065-3233(03)01011-8  0.395
2003 Zhou ZH, Chiu W. Determination of icosahedral virus structures by electron cryomicroscopy at subnanometer resolution Advances in Protein Chemistry. 64: 93-124. PMID 13677046 DOI: 10.1016/S0065-3233(03)01003-9  0.382
2003 Chiu W, Johnson JE. Virus structure: Preface Advances in Protein Chemistry. 64: xi-xii. PMID 13677043 DOI: 10.1016/S0065-3233(03)09001-6  0.308
2003 Baker ML, Jiang W, Bowman BR, Zhou ZH, Quiocho FA, Rixon FJ, Chiu W. Architecture of the herpes simplex virus major capsid protein derived from structural bioinformatics. Journal of Molecular Biology. 331: 447-56. PMID 12888351 DOI: 10.1016/S0022-2836(03)00696-X  0.478
2003 Serysheva II, Bare DJ, Ludtke SJ, Kettlun CS, Chiu W, Mignery GA. Structure of the type 1 inositol 1,4,5-trisphosphate receptor revealed by electron cryomicroscopy. The Journal of Biological Chemistry. 278: 21319-22. PMID 12714606 DOI: 10.1074/Jbc.C300148200  0.638
2003 Bowman BR, Baker ML, Rixon FJ, Chiu W, Quiocho FA. Structure of the herpesvirus major capsid protein. The Embo Journal. 22: 757-65. PMID 12574112 DOI: 10.1093/Emboj/Cdg086  0.418
2003 Ko YH, Delannoy M, Hullihen J, Chiu W, Pedersen PL. Mitochondrial ATP synthasome. Cristae-enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP/ATP. The Journal of Biological Chemistry. 278: 12305-9. PMID 12560333 DOI: 10.1074/Jbc.C200703200  0.301
2003 Jiang W, Li Z, Zhang Z, Baker ML, Prevelige PE, Chiu W. Coat protein fold and maturation transition of bacteriophage P22 seen at subnanometer resolutions. Nature Structural Biology. 10: 131-5. PMID 12536205 DOI: 10.1038/Nsb891  0.452
2003 Paredes A, Alwell-Warda K, Weaver SC, Chiu W, Watowich SJ. Structure of isolated nucleocapsids from venezuelan equine encephalitis virus and implications for assembly and disassembly of enveloped virus. Journal of Virology. 77: 659-64. PMID 12477868 DOI: 10.1128/Jvi.77.1.659-664.2003  0.348
2003 Booth CR, Chen D, Ludtke SJ, Chiu W. Imaging Ice Embedded Single Particles With A 16 Megapixel CCD Camera Microscopy and Microanalysis. 9: 962-963. DOI: 10.1017/S1431927603444814  0.649
2002 Baker ML, Serysheva II, Sencer S, Wu Y, Ludtke SJ, Jiang W, Hamilton SL, Chiu W. The skeletal muscle Ca2+ release channel has an oxidoreductase-like domain. Proceedings of the National Academy of Sciences of the United States of America. 99: 12155-60. PMID 12218169 DOI: 10.1073/Pnas.182058899  0.624
2002 Serysheva II, Ludtke SJ, Baker MR, Chiu W, Hamilton SL. Structure of the voltage-gated L-type Ca2+ channel by electron cryomicroscopy. Proceedings of the National Academy of Sciences of the United States of America. 99: 10370-5. PMID 12149473 DOI: 10.1073/Pnas.162363499  0.576
2002 Chiu W, Baker ML, Jiang W, Zhou ZH. Deriving folds of macromolecular complexes through electron cryomicroscopy and bioinformatics approaches Current Opinion in Structural Biology. 12: 263-269. PMID 11959506 DOI: 10.1016/S0959-440X(02)00319-6  0.512
2002 Rockel B, Jakana J, Chiu W, Baumeister W. Electron cryo-microscopy of VAT, the archaeal p97/CDC48 homologue from Thermoplasma acidophilum. Journal of Molecular Biology. 317: 673-81. PMID 11955016 DOI: 10.1006/Jmbi.2002.5448  0.309
2002 Chiu W, Rixon FJ. High resolution structural studies of complex icosahedral viruses: A brief overview Virus Research. 82: 9-17. PMID 11885957 DOI: 10.1016/S0168-1702(01)00381-1  0.402
2002 Brink J, Ludtke SJ, Yang CY, Gu ZW, Wakil SJ, Chiu W. Quaternary structure of human fatty acid synthase by electron cryomicroscopy. Proceedings of the National Academy of Sciences of the United States of America. 99: 138-43. PMID 11756679 DOI: 10.1073/Pnas.012589499  0.615
2002 Nason L, Chiu W, Ludtke SJ. Development of a Web Based Data Storage and Project Management System for Biological Electron Cryo-microscopy Microscopy and Microanalysis. 8: 1576-1577. DOI: 10.1017/S1431927602104466  0.566
2002 Ludtke SJ, Chiu W. Merging Focal Pairs for Improved Particle Selection and Orientation Determination Microscopy and Microanalysis. 8: 216-217. DOI: 10.1017/S1431927602100341  0.553
2001 Jiang W, Li Z, Zhang Z, Booth CR, Baker ML, Chiu W. Semi-automated icosahedral particle reconstruction at sub-nanometer resolution Journal of Structural Biology. 136: 214-225. PMID 12051901 DOI: 10.1006/Jsbi.2002.4439  0.601
2001 Ludtke SJ, Jakana J, Song JL, Chuang DT, Chiu W. A 11.5 A single particle reconstruction of GroEL using EMAN. Journal of Molecular Biology. 314: 253-62. PMID 11718559 DOI: 10.1006/Jmbi.2001.5133  0.614
2001 Zhou ZH, Baker ML, Jiang W, Dougherty M, Jakana J, Dong G, Lu G, Chiu W. Electron cryomicroscopy and bioinformatics suggest protein fold models for rice dwarf virus. Nature Structural Biology. 8: 868-73. PMID 11573092 DOI: 10.1038/Nsb1001-868  0.501
2001 Paredes A, Alwell-Warda K, Weaver SC, Chiu W, Watowich SJ. Venezuelan equine encephalomyelitis virus structure and its divergence from old world alphaviruses. Journal of Virology. 75: 9532-7. PMID 11533216 DOI: 10.1128/Jvi.75.19.9532-9537.2001  0.355
2001 He J, Schmid MF, Zhou ZH, Rixon F, Chiu W. Finding and using local symmetry in identifying lower domain movements in hexon subunits of the herpes simplex virus type 1 B capsid. Journal of Molecular Biology. 309: 903-14. PMID 11399067 DOI: 10.1006/Jmbi.2001.4711  0.355
2001 Saad A, Ludtke SJ, Jakana J, Rixon FJ, Tsuruta H, Chiu W. Fourier amplitude decay of electron cryomicroscopic images of single particles and effects on structure determination. Journal of Structural Biology. 133: 32-42. PMID 11356062 DOI: 10.1006/Jsbi.2001.4330  0.609
2001 Jiang W, Baker ML, Ludtke SJ, Chiu W. Bridging the information gap: Computational tools for intermediate resolution structure interpretation Journal of Molecular Biology. 308: 1033-1044. PMID 11352589 DOI: 10.1006/Jmbi.2001.4633  0.686
2001 Jiang W, Chiu W. Web-based simulation for contrast transfer function and envelope functions Microscopy and Microanalysis. 7: 329-334. DOI: 10.1017/S1431927601010315  0.359
2000 Thuman-Commike PA, Chiu W. Reconstruction principles of icosahedral virus structure determination using electron cryomicroscopy Micron. 31: 687-711. PMID 10838029 DOI: 10.1016/S0968-4328(99)00077-3  0.393
2000 Zhou ZH, Dougherty M, Jakana J, He J, Rixon FJ, Chiu W. Seeing the herpesvirus capsid at 8.5 A. Science (New York, N.Y.). 288: 877-80. PMID 10797014 DOI: 10.1126/Science.288.5467.877  0.397
2000 Johnson JE, Chiu W. Structures of virus and virus-like particles. Current Opinion in Structural Biology. 10: 229-35. PMID 10753814 DOI: 10.1016/S0959-440X(00)00073-7  0.386
2000 Zhang Z, Greene B, Thuman-Commike PA, Jakana J, Prevelige PE, King J, Chiu W. Visualization of the maturation transition in bacteriophage P22 by electron cryomicroscopy Journal of Molecular Biology. 297: 615-626. PMID 10731416 DOI: 10.1006/Jmbi.2000.3601  0.34
2000 Schmid MF, Sherman MB, Matsudaira P, Tsuruta H, Chiu W. Scaling structure factor amplitudes in electron cryomicroscopy using X-Ray solution scattering. Journal of Structural Biology. 128: 51-7. PMID 10600558 DOI: 10.1006/Jsbi.1999.4173  0.338
2000 Sherman MB, Jakana J, Sun S, Matsudaira P, Chiu W, Schmid MF. The three-dimensional structure of the Limulus acrosomal process: a dynamic actin bundle. Journal of Molecular Biology. 294: 139-49. PMID 10556034 DOI: 10.1006/Jmbi.1999.3222  0.387
2000 Sherman MB, Waller G, Matsudaira P, Chiu W, Schmid MF. Electron Crystallographic Structure of the Limulus Acrosomal Bundle at 20 Å Resolution Microscopy and Microanalysis. 6: 242-243. DOI: 10.1017/S1431927600033705  0.393
1999 Ludtke SJ, Baldwin PR, Chiu W. EMAN: semiautomated software for high-resolution single-particle reconstructions. Journal of Structural Biology. 128: 82-97. PMID 10600563 DOI: 10.1006/Jsbi.1999.4174  0.608
1999 Orlova EV, Sherman MB, Chiu W, Mowri H, Smith LC, Gotto AM. Three-dimensional structure of low density lipoproteins by electron cryomicroscopy. Proceedings of the National Academy of Sciences of the United States of America. 96: 8420-5. PMID 10411890 DOI: 10.1073/Pnas.96.15.8420  0.311
1999 Thuman-Commike PA, Greene B, Malinski JA, Burbea M, McGough A, Chiu W, Prevelige PE. Mechanism of scaffolding-directed virus assembly suggested by comparison of scaffolding-containing and scaffolding-lacking P22 procapsids. Biophysical Journal. 76: 3267-77. PMID 10354452 DOI: 10.1016/S0006-3495(99)77479-5  0.308
1999 Chiu W, McGough A, Sherman MB, Schmid MF. High-resolution electron cryomicroscopy of macromolecular assemblies. Trends in Cell Biology. 9: 154-9. PMID 10203794 DOI: 10.1016/S0962-8924(99)01511-1  0.391
1999 Thuman-Commike PA, Tsuruta H, Greene B, Prevelige PE, King J, Chiu W. Solution x-ray scattering-based estimation of electron cryomicroscopy imaging parameters for reconstruction of virus particles Biophysical Journal. 76: 2249-2261. PMID 10096920 DOI: 10.1016/S0006-3495(99)77381-9  0.338
1999 Saad A, Zhou ZH, Jakana J, Chiu W, Rixon FJ. Roles of Triplex and Scaffolding Proteins in Herpes Simplex Virus Type 1 Capsid Formation Suggested by Structures of Recombinant Particles Journal of Virology. 73: 6821-6830. DOI: 10.1128/Jvi.73.8.6821-6830.1999  0.369
1999 Zhou ZH, Chen DH, Jakana J, Rixon FJ, Chiu W. Visualization of Tegument-Capsid Interactions and DNA in Intact Herpes Simplex Virus Type 1 Virions Journal of Virology. 73: 3210-3218. DOI: 10.1128/Jvi.73.4.3210-3218.1999  0.346
1998 Sherman MB, Soejima T, Chiu W, Van Heel M. Multivariate analysis of single unit cells in electron crystallography Ultramicroscopy. 74: 179-199. PMID 9809457 DOI: 10.1016/S0304-3991(98)00041-2  0.362
1998 Frey W, Brink J, Schief WR, Chiu W, Vogel V. Electron crystallographic analysis of two-dimensional streptavidin crystals coordinated to metal-chelated lipid monolayers. Biophysical Journal. 74: 2674-9. PMID 9591691 DOI: 10.1016/S0006-3495(98)77973-1  0.304
1998 Zhou ZH, Chiu W, Haskell K, Spears H, Jakana J, Rixon FJ, Scott LR. Refinement of herpesvirus B-capsid structure on parallel supercomputers. Biophysical Journal. 74: 576-88. PMID 9449358 DOI: 10.1016/S0006-3495(98)77816-6  0.361
1998 Paredes AM, Heidner H, Thuman-Commike P, Prasad BV, Johnston RE, Chiu W. Structural localization of the E3 glycoprotein in attenuated Sindbis virus mutants. Journal of Virology. 72: 1534-41. PMID 9445057 DOI: 10.1128/Jvi.72.2.1534-1541.1998  0.303
1998 Sherman MB, Jakana J, Sun S, Matsudaira P, Chiu W, Schmid MF. A strategy for electron tomographic data collection and crystallographic reconstruction of biological bundles. Journal of Structural Biology. 120: 245-56. PMID 9441930 DOI: 10.1006/Jsbi.1997.3916  0.366
1998 Lu G, Zhou ZH, Baker ML, Jakana J, Cai D, Wei X, Chen S, Gu X, Chiu W. Structure of Double-Shelled Rice Dwarf Virus Journal of Virology. 72: 8541-8549. DOI: 10.1128/Jvi.72.11.8541-8549.1998  0.361
1998 Ludtke S, Serysheva I, Hamilton SL, Chiu W. CTF Corrected Structure of the Closed-State Calcium Release Channel Microscopy and Microanalysis. 4: 950-951. DOI: 10.1017/S1431927600024879  0.557
1997 Sherman MB, Chiu W. Reliability of phases retrieved from 400-kV spot-scan images of purple membranes acquired on a slow-scan CCD camera Journal of Microscopy. 188: 285-289. PMID 9450331 DOI: 10.1046/J.1365-2818.1997.2450803.X  0.303
1997 Grimes JM, Jakana J, Ghosh M, Basak AK, Roy P, Chiu W, Stuart DI, Prasad BVV. An atomic model of the outer layer of the bluetongue virus core derived from X-ray crystallography and electron cryomicroscopy Structure. 5: 885-893. PMID 9261080 DOI: 10.1016/S0969-2126(97)00243-8  0.36
1997 Chiu W, Avila-Sakar AJ, Schmid MF. Electron crystallography of macromolecular periodic arrays on phospholipid monolayers. Advances in Biophysics. 34: 161-72. PMID 9204133 DOI: 10.1016/S0065-227X(97)89638-4  0.371
1997 Chiu W, Schmid MF. Pushing back the limits of electron cryomicroscopy Nature Structural Biology. 4: 331-333. PMID 9145097 DOI: 10.1038/Nsb0597-331  0.356
1997 Sherman MB, Jakana J, Sunt S, Matsudaira p, Chiu W, Schmid MF. New Strategy for Crystallographic Reconstruction of Biological Bundle-Like Structures Microscopy and Microanalysis. 3: 1035-1036. DOI: 10.1017/S143192760001206X  0.31
1997 Schmid MF, Sherman MB, Brink J, Jakana J, Kelsey M, Dougherty M, Chiu W. Exploring Macromolecular Interactions at High Resolution Using Electron Cryomicroscopy at NCMI Microscopy and Microanalysis. 3: 279-280. DOI: 10.1017/S143192760000828X  0.32
1996 Avila-Sakar AJ, Chiu W.. Visualization of beta-sheets and side-chain clusters in two-dimensional periodic arrays of streptavidin on phospholipid monolayers by electron crystallography. Biophys J. 71: 57–68. PMID 8770187 DOI: 10.1016/S0006-3495(96)79597-8  0.382
1996 Zhou ZH, Hardt S, Wang B, Sherman MB, Jakana J, Chiu W. CTF determination of images of ice-embedded single particles using a graphics interface. Journal of Structural Biology. 116: 216-22. PMID 8742746 DOI: 10.1006/Jsbi.1996.0033  0.318
1996 Thuman-Commike PA, Chiu W. PTOOL: A software package for the selection of particles from electron cryomicroscopy spot-scan images Journal of Structural Biology. 116: 41-47. PMID 8742721 DOI: 10.1006/Jsbi.1996.0008  0.313
1996 Prasad BVV, Rothnagel R, Zeng CQ-, Jakana J, Lawton JA, Chiu W, Estes MK. Visualization of ordered genomic RNA and localization of transcriptional complexes in rotavirus Nature. 382: 471-473. PMID 8684490 DOI: 10.1038/382471A0  0.312
1996 Thuman-Commike PA, Greene B, Jakana J, Prasad BVV, King J, Prevelige PE, Chiu W. Three-dimensional structure of scaffolding-containing phage P22 procapsids by electron cryo-microscopy Journal of Molecular Biology. 260: 85-98. PMID 8676394 DOI: 10.1006/Jmbi.1996.0383  0.363
1995 Serysheva II, Orlova EV, Chiu W, Sherman MB, Hamilton SL, van Heel M. Electron cryomicroscopy and angular reconstitution used to visualize the skeletal muscle calcium release channel. Nature Structural Biology. 2: 18-24. PMID 7719847 DOI: 10.1038/Nsb0195-18  0.364
1994 Schmid MF, Agris JM, Jakana J, Matsudaira P, Chiu W. Three-dimensional structure of a single filament in the Limulus acrosomal bundle: scruin binds to homologous helix-loop-beta motifs in actin. The Journal of Cell Biology. 124: 341-50. PMID 8294517 DOI: 10.1083/Jcb.124.3.341  0.329
1994 Sines J, Rothnagel R, van Heel M, Gaubatz JW, Morrisett JD, Chiu W. Electron cryomicroscopy and digital image processing of lipoprotein(a) Chemistry and Physics of Lipids. 67: 81-89. PMID 8187247 DOI: 10.1016/0009-3084(94)90126-0  0.344
1994 Schmid MF, Prasad BV, Chiu W. Structural studies of viruses by electron cryomicroscopy. Archives of Virology. Supplementum. 9: 523-9. PMID 8032281 DOI: 10.1007/978-3-7091-9326-6_50  0.399
1994 Avila-Sakar AJ, Guan TL, Arad T, Schmid MF, Loke TW, Yonath A, Piefke J, Franceschi F, Chiu W. Electron cryomicroscopy of Bacillus stearothermophilus 50 S ribosomal subunits crystallized on phospholipid monolayers. Journal of Molecular Biology. 239: 689-97. PMID 8014989 DOI: 10.1006/Jmbi.1994.1406  0.375
1994 Zhou ZH, Prasad BV, Jakana J, Rixon FJ, Chiu W. Protein subunit structures in the herpes simplex virus A-capsid determined from 400 kV spot-scan electron cryomicroscopy. Journal of Molecular Biology. 242: 456-69. PMID 7932703 DOI: 10.1006/Jmbi.1994.1594  0.4
1994 Brink J, Chiu W. Applications of a slow-scan CCD camera in protein electron crystallography Journal of Structural Biology. 113: 23-34. PMID 7880650 DOI: 10.1006/Jsbi.1994.1029  0.344
1994 Chiu W, Smith TJ. Structural studies of virus-antibody complexes by electron cryomicroscopy and X-ray crystallography Current Opinion in Structural Biology. 4: 219-224. DOI: 10.1016/S0959-440X(94)90311-5  0.346
1993 Prasad BVV, Prevelige PE, Marietta E, Chen RO, Thomas D, King J, Chiu W. Three-dimensional transformation of capsids associated with genome packaging in a bacterial virus Journal of Molecular Biology. 231: 65-74. PMID 8496966 DOI: 10.1006/Jmbi.1993.1257  0.392
1993 Avila-Sakar AJ, Schmid MF, Li LS, Whitby FG, Phillips GN, Chiu W. Preliminary electron crystallographic analysis of ice-embedded tropomyosin crystals. Journal of Structural Biology. 110: 67-74. PMID 8494673 DOI: 10.1006/Jsbi.1993.1005  0.357
1993 Zhou ZH, Chiu W. Prospects for using an IVEM with a FEG for imaging macromolecules towards atomic resolution Ultramicroscopy. 49: 407-416. PMID 8475604 DOI: 10.1016/0304-3991(93)90246-T  0.343
1993 Frank J, Chiu W, Henderson R. Flopping polypeptide chains and Suleika's subtle imperfections: analysis of variations in the electron micrograph of a purple membrane crystal. Ultramicroscopy. 49: 387-96. PMID 8475603 DOI: 10.1016/0304-3991(93)90244-R  0.484
1993 Paredes AM, Brown DT, Rothnagel R, Chiu W, Schoepp RJ, Johnston RE, Prasad BV. Three-dimensional structure of a membrane-containing virus. Proceedings of the National Academy of Sciences of the United States of America. 90: 9095-9. PMID 8415660 DOI: 10.1073/Pnas.90.19.9095  0.386
1993 Shaw AL, Rothnagel R, Chen D, Ramig RF, Chiu W, Prasad BVV. Three-dimensional visualization of the rotavirus hemagglutinin structure Cell. 74: 693-701. PMID 8395350 DOI: 10.1016/0092-8674(93)90516-S  0.396
1993 Chiu W, Schmid MF, Prasad BV. Teaching electron diffraction and imaging of macromolecules. Biophysical Journal. 64: 1610-25. PMID 8324196 DOI: 10.1016/S0006-3495(93)81533-9  0.395
1993 Leapman RD, Brink J, Chiu W. Low-dose thickness measurement of glucose-embedded protein crystals by electron energy loss spectroscopy and STEM dark-field imaging. Ultramicroscopy. 52: 157-66. PMID 8291165 DOI: 10.1016/0304-3991(93)90186-2  0.319
1993 Chiu W, Schmid MF. Electron crystallography of macromolecules Current Opinion in Biotechnology. 4: 397-402. PMID 7763969 DOI: 10.1016/0958-1669(93)90004-G  0.387
1993 Brink J, Chiu W, Dougherty M. Computer-controlled spot-scan imaging of crotoxin complex crystals with 400 keV electrons at near-atomic resolution. Ultramicroscopy. 46: 229-40. PMID 1481273 DOI: 10.1016/0304-3991(92)90017-E  0.347
1992 Schmid MF, Jakana J, Matsudaira P, Chiu W. Effects of radiation damage with 400-kV electrons on frozen, hydrated actin bundles. Journal of Structural Biology. 108: 62-8. PMID 1562434 DOI: 10.1016/1047-8477(92)90007-W  0.33
1992 Morgan DG, Grant RA, Chiu W, Frank J. Patch averaging of electron images of GP32*I crystals with variable thickness Journal of Structural Biology. 108: 245-256. PMID 1335748 DOI: 10.1016/1047-8477(92)90025-6  0.477
1991 Brink J, Chiu W. Contrast analysis of cryo-images of n-paraffin recorded at 400 kV out to 2.1 Å resolution Journal of Microscopy. 161: 279-295. PMID 2038034 DOI: 10.1111/J.1365-2818.1991.Tb03090.X  0.32
1991 Schmid MF, Matsudaira P, Jeng TW, Jakana J, Towns-Andrews E, Bordas J, Chiu W. Crystallographic analysis of acrosomal bundle from Limulus sperm. Journal of Molecular Biology. 221: 711-25. PMID 1920441 DOI: 10.1016/0022-2836(91)80082-6  0.357
1991 Grant RA, Schmid MF, Chiu W. Analysis of symmetry and three-dimensional reconstruction of thin gp32*I crystals. Journal of Molecular Biology. 217: 551-562. PMID 1847218 DOI: 10.1016/0022-2836(91)90757-W  0.305
1990 Prasad BVV, Burns JW, Marietta E, Estes MK, Chiu W. Localization of VP4 neutralization sites in rotavirus by three-dimensional cryo-electron microscopy Nature. 343: 476-479. PMID 2153941 DOI: 10.1038/343476A0  0.363
1990 Downing KH, Chiu W. Cold stage design for high resolution electron microscopy of biological materials Electron Microscopy Reviews. 3: 213-226. PMID 2103342 DOI: 10.1016/0892-0354(90)90002-A  0.353
1989 Frank J, Chiu W, Degn L. The characterization of structural variations within a crystal field. Ultramicroscopy. 26: 345-60. PMID 3238812 DOI: 10.1016/0304-3991(88)90234-3  0.476
1989 Jeng TW, Crowther RA, Stubbs G, Chiu W. Visualization of alpha-helices in tobacco mosaic virus by cryo-electron microscopy. Journal of Molecular Biology. 205: 251-7. PMID 2926805 DOI: 10.1016/0022-2836(89)90379-3  0.405
1989 Schrag JD, Prasad BV, Rixon FJ, Chiu W. Three-dimensional structure of the HSV1 nucleocapsid. Cell. 56: 651-60. PMID 2537151 DOI: 10.1016/0092-8674(89)90587-4  0.302
1988 Robinson JP, Schmid MF, Morgan DG, Chiu W. Three-dimensional structural analysis of tetanus toxin by electron crystallography Journal of Molecular Biology. 200: 367-375. PMID 3373534 DOI: 10.1016/0022-2836(88)90247-1  0.379
1988 Chang CF, Rankert DA, Jeng TW, Morgan DG, Schmid MF, Chiu W. Cryo electron microscopy of unstained, unfixed RecA-cssDNA complexes Journal of Ultrastructure Research and Molecular Structure Research. 100: 166-172. PMID 3066826 DOI: 10.1016/0889-1605(88)90023-7  0.331
1988 Prasad BV, Wang GJ, Clerx JP, Chiu W. Three-dimensional structure of rotavirus. Journal of Molecular Biology. 199: 269-75. PMID 2832610 DOI: 10.1016/0022-2836(88)90313-0  0.393
1987 Jeng TW, Chiu W. High resolution cryo system designed for JEM 100CX electron microscope Ultramicroscopy. 23: 61-66. PMID 3660492 DOI: 10.1016/0304-3991(87)90227-0  0.351
1987 Chiu W, Jeng TW, Degn LL, Prasad BV. Potential for high-resolution electron crystallography at intermediate high voltage. Annals of the New York Academy of Sciences. 483: 149-56. PMID 3471122 DOI: 10.1111/J.1749-6632.1986.Tb34510.X  0.309
1987 Venkataram Prasad BV, Chiu W. Sequence comparison of single-stranded DNA binding proteins and its structural implications Journal of Molecular Biology. 193: 579-584. PMID 3295261 DOI: 10.1016/0022-2836(87)90268-3  0.31
1987 Talmon Y, Prasad BV, Clerx JP, Wang GJ, Chiu W, Hewlett MJ. Electron microscopy of vitrified-hydrated La Crosse virus. Journal of Virology. 61: 2319-2321. DOI: 10.1128/Jvi.61.7.2319-2321.1987  0.334
1987 Prasad B, Wang G, Clerx J, Chiu W. Cryo electron microscopy of spherical viruses: An application to rotaviruses Micron and Microscopica Acta. 18: 327-331. DOI: 10.1016/0739-6260(87)90033-5  0.39
1987 Chiu W, Jeng T, Degn L, Crant R, Schmid M, Prasad B. High resolution cryo-electron microscopy of biological specimens Ultramicroscopy. 23: 232. DOI: 10.1016/0304-3991(87)90172-0  0.341
1986 Grant RA, Schmid MF, Chiu W, Deatherage JF, Hosoda J. Alignment and merging of electron microscope images of frozen hydrated crystals of the T4 DNA helix destabilizing protein gp32*I. Biophysical Journal. 49: 251-8. PMID 3513856 DOI: 10.1016/S0006-3495(86)83638-4  0.342
1984 Jeng TW, Chiu W, Zemlin F, Zeitler E. Electron imaging of crotoxin complex thin crystal at 3.5 Å Journal of Molecular Biology. 175: 93-97. PMID 6726806 DOI: 10.1016/0022-2836(84)90449-2  0.355
1984 Cohen HA, Jeng TW, Grant RA, Chiu W. Specimen preparative methods for electron crystallography of soluble proteins. Ultramicroscopy. 13: 19-25. PMID 6540906 DOI: 10.1016/0304-3991(84)90053-6  0.335
1984 Jeng TW, Chiu W. Experimental strategy in three-dimensional structure determination of crotoxin complex thin crystal Ultramicroscopy. 13: 27-34. PMID 6474598 DOI: 10.1016/0304-3991(84)90054-8  0.333
1984 Chiu W. The 1983 symposium on electron crystallography of macromolecules Ultramicroscopy. 13. DOI: 10.1016/0304-3991(84)90050-0  0.309
1983 Jeng TW, Chiu W. Low dose electron microscopy of the crotoxin complex thin crystal Journal of Molecular Biology. 164: 329-346. PMID 6842594 DOI: 10.1016/0022-2836(83)90080-3  0.342
1983 Cohen H, Chiu W, Cohen HA. Structural analysis of T4 DNA helix destabilizing protein (gp32*I) crystal by electron microscopy Journal of Molecular Biology. 169: 235-248. PMID 6312050 DOI: 10.1016/S0022-2836(83)80182-X  0.374
1982 Kellenberger E, Chiu W. Perspectives and outlook for electron microscopy in biology in general. Ultramicroscopy. 10: 165-77. PMID 6182665 DOI: 10.1016/0304-3991(82)90196-6  0.379
1979 Glaeser RM, Chiu W, Grano D. Structure of the surface layer protein of the outer membrane of Spirillum serpens. Journal of Ultrastructure Research. 66: 235-42. PMID 439191 DOI: 10.1016/S0022-5320(79)90121-7  0.535
1978 Chiu W, Hosoda J. Crystallization and preliminary electron diffraction study to 3.7 Å of DNA helix-destabilizing protein gp32*I Journal of Molecular Biology. 122: 103-107. PMID 209194 DOI: 10.1016/0022-2836(78)90110-9  0.303
1977 Chiu W, Glaeser RM. Factors affecting high resolution fixed-beam transmission electron microscopy. Ultramicroscopy. 2: 207-17. PMID 888240 DOI: 10.1016/S0304-3991(76)91334-6  0.555
1975 Chiu W, Glaeser RM. Single atom image contrast: conventional dark-field and bright-field electron microscopy. Journal of Microscopy. 103: 33-54. PMID 1095752 DOI: 10.1111/J.1365-2818.1975.Tb04535.X  0.52
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