Timothy M. Hanley, Ph.D.

Affiliations: 
2011 Boston University, Boston, MA, United States 
Area:
Microbiology Biology, Virology Biology
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"Timothy Hanley"

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Gregory A. Viglianti grad student 2011 Boston University
 (The effects of nuclear receptor and Toll-like receptor crosstalk on HIV-1 replication in and transmission by macrophages and dendritic cells.)
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Publications

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Williams ESCP, Szaniawski MA, Martins LJ, et al. (2022) Dasatinib: effects on the macrophage phospho proteome with a focus on SAMHD1 and HIV-1 infection. Clinical Research in Hiv/Aids. 8
Dickey LL, Martins LJ, Planelles V, et al. (2022) HIV-1-induced type I IFNs promote viral latency in macrophages. Journal of Leukocyte Biology
Martins LJ, Szaniawski MA, Williams ESCP, et al. (2022) HIV-1 Accessory Proteins Impart a Modest Interferon Response and Upregulate Cell Cycle-Related Genes in Macrophages. Pathogens (Basel, Switzerland). 11
Viglianti GA, Planelles V, Hanley TM. (2021) Interactions with Commensal and Pathogenic Bacteria Induce HIV-1 Latency in Macrophages through Altered Transcription Factor Recruitment to the LTR. Journal of Virology
Szaniawski MA, Spivak AM, Cox JE, et al. (2018) SAMHD1 Phosphorylation Coordinates the Anti-HIV-1 Response by Diverse Interferons and Tyrosine Kinase Inhibition. Mbio. 9
Dickey LL, Duncan JK, Hanley TM, et al. (2015) Decapping protein 1 phosphorylation modulates IL-8 expression during respiratory syncytial virus infection. Virology. 481: 199-209
Hanley TM, Viglianti GA. (2011) Nuclear receptor signaling inhibits HIV-1 replication in macrophages through multiple trans-repression mechanisms. Journal of Virology. 85: 10834-50
Hanley TM, Blay Puryear W, Gummuluru S, et al. (2010) PPARgamma and LXR signaling inhibit dendritic cell-mediated HIV-1 capture and trans-infection. Plos Pathogens. 6: e1000981
Kiefer HL, Hanley TM, Marcello JE, et al. (2004) Retinoic acid inhibition of chromatin remodeling at the human immunodeficiency virus type 1 promoter. Uncoupling of histone acetylation and chromatin remodeling. The Journal of Biological Chemistry. 279: 43604-13
Hanley TM, Kiefer HL, Schnitzler AC, et al. (2004) Retinoid-dependent restriction of human immunodeficiency virus type 1 replication in monocytes/macrophages. Journal of Virology. 78: 2819-30
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