Kimberley A. Lentz, Ph.D.

Affiliations: 
2000 University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Pharmacy, Pharmaceutical Chemistry
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"Kimberley Lentz"

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James E. Polli grad student 2000 University of Maryland Medical School
 (Development of passive and active absorption models and their relevance to dosage form absorption kinetics.)
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Publications

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Kostich W, Hamman BD, Li YW, et al. (2016) Inhibition of AAK1 kinase as a novel therapeutic approach to treat neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics
Toyn JH, Boy KM, Raybon J, et al. (2016) Robust translation of GSM pharmacology across preclinical species and human subjects. The Journal of Pharmacology and Experimental Therapeutics
Soares HD, Gasior M, Toyn JH, et al. (2016) The Gamma Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and CSF of Healthy Volunteers. The Journal of Pharmacology and Experimental Therapeutics
Ahuja VT, Hartz RA, Molski TF, et al. (2016) Synthesis and evaluation of carbamate and aryl ether substituted pyrazinones as corticotropin releasing factor-1 (CRF1) receptor antagonists. Bioorganic & Medicinal Chemistry Letters
Shi J, Zuev D, Xu L, et al. (2015) Design and optimization of tricyclic gamma-secretase modulators. Bioorganic & Medicinal Chemistry Letters
Boy KM, Guernon JM, Wu YJ, et al. (2015) Macrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE). Bioorganic & Medicinal Chemistry Letters
Toyn JH, Thompson LA, Lentz KA, et al. (2014) Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780. International Journal of Alzheimer's Disease. 2014: 431858
Vivian D, Cheng K, Khurana S, et al. (2013) Design and characterization of a novel fluorinated magnetic resonance imaging agent for functional analysis of bile Acid transporter activity. Pharmaceutical Research. 30: 1240-51
Albright CF, Dockens RC, Meredith JE, et al. (2013) Pharmacodynamics of selective inhibition of γ-secretase by avagacestat. The Journal of Pharmacology and Experimental Therapeutics. 344: 686-95
Luo G, Chen L, Conway CM, et al. (2012) Discovery of BMS-846372, a Potent and Orally Active Human CGRP Receptor Antagonist for the Treatment of Migraine. Acs Medicinal Chemistry Letters. 3: 337-41
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