Brian P. Sorrentino

Affiliations: 
Molecular Therapeutics and Cell Signaling University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Molecular Biology, Immunology, Epidemiology, Oncology
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"Brian Sorrentino"
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Publications

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Bonner MA, Morales-Hernández A, Zhou S, et al. (2021) 3' UTR-truncated HMGA2 overexpression induces non-malignant expansion of hematopoietic stem cells in non-human primates. Molecular Therapy. Methods & Clinical Development. 21: 693-701
Ozog S, Timberlake ND, Hermann K, et al. (2019) Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes. Blood
Mamcarz E, Zhou S, Lockey T, et al. (2019) Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1. The New England Journal of Medicine. 380: 1525-1534
Fatima S, Zhou S, Sorrentino BP. (2018) Marking of definitive HSC precursors in E7.5-E8.5 embryos using an Abcg2-CreER lineage tracing mouse model. Experimental Hematology
Fukuda Y, Wang Y, Lian S, et al. (2017) Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis. Jci Insight. 2
Mamcarz E, Zhou S, Lockey T, et al. (2017) Interim Results from a Phase I/II Clinical Gene Therapy Study for Newly Diagnosed Infants with X-Linked Severe Combined Immunodeficiency Using a Safety-Modified Lentiviral Vector and Targeted Reduced Exposure to Busulfan Blood. 130: 523-523
De Ravin SS, Wu X, Moir S, et al. (2016) Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency. Science Translational Medicine. 8: 335ra57
Zhou S, Fatima S, Ma Z, et al. (2016) Evaluating the safety of retroviral vectors based on insertional oncogene activation and blocked differentiation in cultured thymocytes. Molecular Therapy : the Journal of the American Society of Gene Therapy
Zhou S, Ma Z, Lu T, et al. (2016) 571. Safe Harbor Targeting of IL2RG Expression Cassettes for Gene Therapy of X-Linked Severe Combined Immunodeficiency (SCID-X1) Molecular Therapy. 24: S228
Bonner MA, Zhou S, Wang Y, et al. (2016) 281. Enforced Expression of a Mutant HMGA2 Gene Leads to Competitive Expansion and High Level Marking of Long-Term Hematopoietic Stem Cells in Transplanted Nemestrina Macaques Molecular Therapy. 24: S112-S113
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