Konstantin S. Leskov, Ph.D.
Affiliations: | 2001 | University of Wisconsin, Madison, Madison, WI |
Area:
Molecular Biology, Cell Biology, OncologyGoogle:
"Konstantin Leskov"Parents
Sign in to add mentor| Timothy J. Kinsella | grad student | 2001 | UW Madison | |
| (Ku70 -binding proteins: Structure-functional analyses of clusterin (CLU).) | ||||
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Publications
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| Morales JC, Richard P, Rommel A, et al. (2014) Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair. Nucleic Acids Research. 42: 4996-5006 |
| Zhang Z, Liu Q, Leskov KS, et al. (2013) Roscovitine suppresses CD4+ T cells and T cell-mediated experimental uveitis. Plos One. 8: e81154 |
| Klokov D, Leskov K, Araki S, et al. (2013) Low dose IR-induced IGF-1-sCLU expression: a p53-repressed expression cascade that interferes with TGFβ1 signaling to confer a pro-survival bystander effect. Oncogene. 32: 479-90 |
| Leskov KS, Araki S, Lavik JP, et al. (2011) CRM1 protein-mediated regulation of nuclear clusterin (nCLU), an ionizing radiation-stimulated, Bax-dependent pro-death factor. The Journal of Biological Chemistry. 286: 40083-90 |
| Klokov D, Leskov K, Araki S, et al. (2011) Low dose IR-induced IGF-1-sCLU expression: a p53-repressed expression cascade that interferes with TGFß1 signaling to confer survival Nature Precedings |
| Alabran JL, Cheuk A, Liby K, et al. (2008) Human neuroblastoma cells rapidly enter cell cycle arrest and apoptosis following exposure to C-28 derivatives of the synthetic triterpenoid CDDO. Cancer Biology & Therapy. 7: 709-17 |
| Gomez JA, Gama V, Yoshida T, et al. (2007) Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides. Biochemical Society Transactions. 35: 797-801 |
| Sutton D, Kim S, Shuai X, et al. (2006) Efficient suppression of secretory clusterin levels by polymer-siRNA nanocomplexes enhances ionizing radiation lethality in human MCF-7 breast cancer cells in vitro. International Journal of Nanomedicine. 1: 155-62 |
| Shannan B, Seifert M, Leskov K, et al. (2006) Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer. Cell Death and Differentiation. 13: 12-9 |
| Criswell T, Beman M, Araki S, et al. (2005) Delayed activation of insulin-like growth factor-1 receptor/Src/MAPK/Egr-1 signaling regulates clusterin expression, a pro-survival factor. The Journal of Biological Chemistry. 280: 14212-21 |