Aarron Willingham
Affiliations: | Merck & Co. |
Area:
biologics discovery and cell-based assaysGoogle:
"Aarron Willingham"Mean distance: (not calculated yet)
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Publications
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| Sukumar S, Wilson DC, Yu Y, et al. (2017) Characterization of MK-4166, a clinical agonistic antibody that targets human GITR and inhibits the generation and suppressive effects of T regulatory cells. Cancer Research |
| Kenski DM, Butora G, Willingham AT, et al. (2012) siRNA-optimized Modifications for Enhanced In Vivo Activity. Molecular Therapy. Nucleic Acids. 1: e5 |
| Chorn G, Klein-McDowell M, Zhao L, et al. (2012) Single-stranded microRNA mimics. Rna (New York, N.Y.). 18: 1796-804 |
| Fucini RV, Haringsma HJ, Deng P, et al. (2012) Adenosine modification may be preferred for reducing siRNA immune stimulation. Nucleic Acid Therapeutics. 22: 205-10 |
| Kenski DM, Willingham AT, Haringsma HJ, et al. (2012) In vivo activity and duration of short interfering RNAs containing a synthetic 5'-phosphate. Nucleic Acid Therapeutics. 22: 90-5 |
| Haringsma HJ, Li JJ, Soriano F, et al. (2012) mRNA knockdown by single strand RNA is improved by chemical modifications. Nucleic Acids Research. 40: 4125-36 |
| Peacock H, Fucini RV, Jayalath P, et al. (2011) Nucleobase and ribose modifications control immunostimulation by a MicroRNA-122-mimetic RNA Journal of the American Chemical Society. 133: 9200-9203 |
| Graveley BR, Brooks AN, Carlson JW, et al. (2011) The developmental transcriptome of Drosophila melanogaster. Nature. 471: 473-9 |
| Cherbas L, Willingham A, Zhang D, et al. (2011) The transcriptional diversity of 25 Drosophila cell lines. Genome Research. 21: 301-14 |
| Kenski DM, Cooper AJ, Li JJ, et al. (2010) Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo. Nucleic Acids Research. 38: 660-71 |