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Alexander Neumann

Affiliations: 
2019- VIB-UAntwerp Center for Molecular Neurology 
Area:
Psychiatric and Neuroepidemiology
Website:
https://www.uantwerpen.be/en/staff/alexander-neumann/research/
Google:
"Alexander Neumann VIB"
Bio:

Dr. Neumann currently studies the genetics of Alzheimer’s disease biomarkers, by examining rare genetic variants obtained from whole exome sequencing (WES). The work focuses on pleiotropic effects on multiple biomarkers, as well as mediation analyses to test whether genes influencing Alzheimer's risk do so by affecting biomarker levels. Dr. Neumann obtained a PhD in psychiatric epidemiology from Erasmus University Rotterdam. The PhD thesis focuses on the genetics and epigenetics of child psychopathology, as well as the co-occurrence of child psychiatric problems. Dr. Neumann has experience leading genome-wide (GWAS) and epigenome-wide association studies (EWAS) in international consortia, such as the The EArly Genetics and Lifecourse Epidemiology (EAGLE) and Pregnancy And Childhood Epigenetics (PACE) consortia. He also worked on white matter integrity in relation to general psychopathology in childhood, as well as on the genetics of cortisol.

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Parents

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Marian Bakermans-Kranenburg grad student 2014-2019 Erasmus MC (EduTree)
Henning Tiemeier grad student 2014-2019 Erasmus MC
Marinus van IJzendoorn grad student 2014-2019 Erasmus MC (EduTree)
Kristel Sleegers post-doc 2020- VIB-UAntwerp Center for Molecular Neurology
Ashley Wazana post-doc 2018-2020 Montreal Jewish General Hospital

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Publications

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Neumann A, Pingault JB, Felix JF, et al. (2022) Epigenome-wide contributions to individual differences in childhood phenotypes: a GREML approach. Clinical Epigenetics. 14: 53
Jami ES, Hammerschlag AR, Ip HF, et al. (2022) Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms. Journal of the American Academy of Child and Adolescent Psychiatry
Caramaschi D, Neumann A, Cardenas A, et al. (2022) Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills. Molecular Psychiatry
Neumann A, Jolicoeur-Martineau A, Szekely E, et al. (2021) Combined polygenic risk scores of different psychiatric traits predict general and specific psychopathology in childhood. Journal of Child Psychology and Psychiatry, and Allied Disciplines
Ip HF, van der Laan CM, Krapohl EML, et al. (2021) Genetic association study of childhood aggression across raters, instruments, and age. Translational Psychiatry. 11: 413
Bolhuis K, Steenkamp LR, Blanken LME, et al. (2021) Schizophrenia polygenic risk is associated with child mental health problems through early childhood adversity: evidence for a gene-environment correlation. European Child & Adolescent Psychiatry
Crawford AA, Bankier S, Altmaier E, et al. (2021) Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease. Journal of Human Genetics
Mulder RH, Neumann A, Cecil CAM, et al. (2021) Epigenome-wide change and variation in DNA methylation in childhood: Trajectories from birth to late adolescence. Human Molecular Genetics
Dall' Aglio L, Rijlaarsdam J, Mulder RH, et al. (2020) Epigenome-wide associations between observed maternal sensitivity and offspring DNA methylation: a population-based prospective study in children. Psychological Medicine. 1-11
Neumann A, Walton E, Alemany S, et al. (2020) Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis. Translational Psychiatry. 10: 398
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