Amira Eldefrawi - Publications

Affiliations: 
1985- Chemistry Maryland 

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Saito Y, Takahashi S, Azer N, Eldefrawi AT, Eldefrawi ME, Takahata H. Catalytic asymmetric synthesis of both enantiomers of pyrrolizidines 223H', 239K', 265H', and 267H' found in madagascan frogs (Mantella) and their affinities for nicotinic acetylcholine receptor Heterocycles. 79: 1043-1060. DOI: 10.3987/COM-08-S(D)81  0.322
2003 Menegatti R, Cunha AC, Ferreira VF, Perreira EF, El-Nabawi A, Eldefrawi AT, Albuquerque EX, Neves G, Rates SM, Fraga CA, Barreiro EJ. Design, synthesis and pharmacological profile of novel dopamine D2 receptor ligands. Bioorganic & Medicinal Chemistry. 11: 4807-13. PMID 14556797 DOI: 10.1016/S0968-0896(03)00487-5  0.36
2000 El-Nabawi A, Quesenberry M, Saito K, Silbergeld E, Vasta G, Eldefrawi A. The N-methyl-D-aspartate neurotransmitter receptor is a mammalian brain target for the dinoflagellate Pfiesteria piscicida toxin. Toxicology and Applied Pharmacology. 169: 84-93. PMID 11076700 DOI: 10.1006/Taap.2000.9042  0.521
2000 Takahata H, Takahashi S, Azer N, Eldefrawi AT, Eldefrawi ME. Total synthesis of pyrrolizidines 223H', 239K', 265H', and 267H' found in Madagascan frogs (Mantella) and their affinities for nicotinic acetylcholine receptor. Bioorganic & Medicinal Chemistry Letters. 10: 1293-5. PMID 10866403 DOI: 10.1016/S0960-894X(00)00221-3  0.324
1998 Takahata H, Kubota M, Ihara K, Okamoto N, Momose T, Azer N, Eldefrawi AT, Eldefrawi ME. New synthesis of all the four stereoisomers of indolizidine 209D and their affinity for nicotinic acetylcholine receptor Tetrahedron Asymmetry. 9: 3289-3301. DOI: 10.1016/S0957-4166(98)00338-3  0.404
1997 Katz EJ, Cortes VI, Eldefrawi ME, Eldefrawi AT. Chlorpyrifos, parathion, and their oxons bind to and desensitize a nicotinic acetylcholine receptor: relevance to their toxicities. Toxicology and Applied Pharmacology. 146: 227-36. PMID 9344890 DOI: 10.1006/taap.1997.8201  0.482
1997 Eldefrawi ME, Eldefrawi AT. Comparative Molecular and Pharmacological Properties of Cholinergic Receptors in Insects and Mammals Acs Symposium Series. 658: 327-338.  0.402
1994 Jett DA, Fernando JC, Eldefrawi ME, Eldefrawi AT. Differential regulation of muscarinic receptor subtypes in rat brain regions by repeated injections of parathion. Toxicology Letters. 73: 33-41. PMID 8042201 DOI: 10.1016/0378-4274(94)90186-4  0.33
1994 Nakanishi K, Choi SK, Hwang D, Lerro K, Orlando M, Kalivretenos AG, Eldefrawi A, Eldefrawi M, Usherwood PNR. Bioorganic studies of transmitter receptors with philanthotoxin analogs Pure and Applied Chemistry. 66: 671-678. DOI: 10.1351/Pac199466040671  0.582
1993 Eldefrawi ME, Anis NA, Eldefrawi AT. Glutamate receptor inhibitors as potential insecticides. Archives of Insect Biochemistry and Physiology. 22: 25-39. PMID 8431599 DOI: 10.1002/arch.940220105  0.51
1993 Jett DA, Hill EF, Fernando JC, Eldefrawi ME, Eldefrawi AT. Down-regulation of muscarinic receptors and the m3 subtype in white-footed mice by dietary exposure to parathion. Journal of Toxicology and Environmental Health. 39: 395-415. PMID 8350385 DOI: 10.1080/15287399309531760  0.344
1993 Jett DA, Eldefrawi AT, Eldefrawi ME. Receptor binding assay applied to monitoring the neurotoxicity of parathion to peromyscus after oral exposure Astm Special Technical Publication. 253-262.  0.407
1992 Abdallah EA, Jett DA, Eldefrawi ME, Eldefrawi AT. Differential effects of paraoxon on the M3 muscarinic receptor and its effector system in rat submaxillary gland cells. Journal of Biochemical Toxicology. 7: 125-32. PMID 1328639  0.489
1991 Abdallah EA, Eldefrawi ME, Eldefrawi AT. Pharmacologic characterization of muscarinic receptors of insect brains. Archives of Insect Biochemistry and Physiology. 17: 107-18. PMID 1802028 DOI: 10.1002/arch.940170205  0.492
1991 Goodnow RA, Bukownik R, Nakanishi K, Usherwood PN, Eldefrawi AT, Anis NA, Eldefrawi ME. Synthesis and binding of [125I2]philanthotoxin-343, [125I2]philanthotoxin-343-lysine, and [125I2]philanthotoxin-343-arginine to rat brain membranes. Journal of Medicinal Chemistry. 34: 2389-94. PMID 1652018 DOI: 10.1021/Jm00112A012  0.557
1991 Jett DA, Abdallah EAM, El-Fakahany EE, Eldefrawi ME, Eldefrawi AT. High-affinity activation by paraoxon of a muscarinic receptor subtype in rat brain striatum Pesticide Biochemistry and Physiology. 39: 149-157. DOI: 10.1016/0048-3575(91)90135-9  0.508
1990 Silveira CL, Eldefrawi AT, Eldefrawi ME. Putative M2 muscarinic receptors of rat heart have high affinity for organophosphorus anticholinesterases. Toxicology and Applied Pharmacology. 103: 474-81. PMID 2339420 DOI: 10.1016/0041-008X(90)90320-T  0.471
1990 Anis N, Sherby S, Goodnow R, Niwa M, Konno K, Kallimopoulos T, Bukownik R, Nakanishi K, Usherwood P, Eldefrawi A. Structure-activity relationships of philanthotoxin analogs and polyamines on N-methyl-D-aspartate and nicotinic acetylcholine receptors. The Journal of Pharmacology and Experimental Therapeutics. 254: 764-73. PMID 2168484  0.538
1990 Bruce M, Bukownik R, Eldefrawi AT, Eldefrawi ME, Goodnow R, Kallimopoulos T, Konno K, Nakanishi K, Niwa M, Usherwood PN. Structure-activity relationships of analogues of the wasp toxin philanthotoxin: non-competitive antagonists of quisqualate receptors. Toxicon : Official Journal of the International Society On Toxinology. 28: 1333-46. PMID 1965063 DOI: 10.1016/0041-0101(90)90098-R  0.491
1990 Nakanishi K, Goodnow R, Konno K, Niwa M, Bukownik R, Thomas T, Kallimopoulos A, Usherwood P, Eldefrawi AT, Eldefrawi ME. Philanthotoxin-433 (PhTX-433), a non-competitive glutamate receptor inhibitor Pure and Applied Chemistry. 62: 1223-1230. DOI: 10.1351/Pac199062071223  0.506
1989 Ragsdale D, Gant DB, Anis NA, Eldefrawi AT, Eldefrawi ME, Konno K, Miledi R. Inhibition of rat brain glutamate receptors by philanthotoxin. The Journal of Pharmacology and Experimental Therapeutics. 251: 156-63. PMID 2571715  0.539
1989 Sattelle DB, Buckingham SD, Wafford KA, Sherby SM, Bakry NM, Eldefrawi AT, Eldefrawi ME, May TE. Actions of the insecticide 2(nitromethylene)tetrahydro-1,3-thiazine on insect and vertebrate nicotinic acetylcholine receptors. Proceedings of the Royal Society of London. Series B, Biological Sciences. 237: 501-14. PMID 2479949 DOI: 10.1098/Rspb.1989.0062  0.536
1989 Rozental R, Scoble GT, Albuquerque EX, Idriss M, Sherby S, Sattelle DB, Nakanishi K, Konno K, Eldefrawi AT, Eldefrawi ME. Allosteric inhibition of nicotinic acetylcholine receptors of vertebrates and insects by philanthotoxin. The Journal of Pharmacology and Experimental Therapeutics. 249: 123-30. PMID 2468760  0.513
1989 Wafford KA, Sattelle DB, Gant DB, Eldefrawi AT, Eldefrawi ME. Noncompetitive inhibition of GABA receptors in insect and vertebrate CNS by endrin and lindane Pesticide Biochemistry and Physiology. 33: 213-219. DOI: 10.1016/0048-3575(89)90119-3  0.362
1988 Bakry NM, el-Rashidy AH, Eldefrawi AT, Eldefrawi ME. Direct actions of organophosphate anticholinesterases on nicotinic and muscarinic acetylcholine receptors. Journal of Biochemical Toxicology. 3: 235-59. PMID 3236334  0.545
1988 Eldefrawi AT, Eldefrawi ME, Konno K, Mansour NA, Nakanishi K, Oltz E, Usherwood PN. Structure and synthesis of a potent glutamate receptor antagonist in wasp venom. Proceedings of the National Academy of Sciences of the United States of America. 85: 4910-3. PMID 2838850 DOI: 10.1073/Pnas.85.13.4910  0.482
1988 Matsumoto K, Eldefrawi ME, Eldefrawi AT. Action of polychlorocycloalkane insecticides on binding of [35S]t-butylbicyclophosphorothionate to Torpedo electric organ membranes and stereospecificity of the binding site. Toxicology and Applied Pharmacology. 95: 220-9. PMID 2458634 DOI: 10.1016/0041-008X(88)90158-5  0.419
1988 Ramadan AA, Bakry NM, Marei ASM, Eldefrawi AT, Eldefrawi ME. Actions of pyrethroids on the peripheral benzodiazepine receptor Pesticide Biochemistry and Physiology. 32: 106-113. DOI: 10.1016/0048-3575(88)90003-X  0.428
1988 Ramadan AA, Bakry NM, Marei ASM, Eldefrawi AT, Eldefrawi ME. Action of pyrethroids on GABAA receptor function Pesticide Biochemistry and Physiology. 32: 97-105. DOI: 10.1016/0048-3575(88)90002-8  0.401
1987 Gant DB, Eldefrawi ME, Eldefrawi AT. Cyclodiene insecticides inhibit GABAA receptor-regulated chloride transport. Toxicology and Applied Pharmacology. 88: 313-21. PMID 3033845 DOI: 10.1016/0041-008X(87)90206-7  0.32
1987 Sherby SM, Eldefrawi ME, Wafford KA, Sattelle DB, Eldefrawi AT. Pharmacology of putative glutamate receptors from insect skeletal muscles, insect central nervous system and rat brain. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology. 87: 99-106. PMID 2885148 DOI: 10.1016/0742-8413(87)90189-7  0.38
1987 Gant DB, Eldefrawi ME, Eldefrawi AT. Action of organophosphates on GABAA receptor and voltage-dependent chloride channels. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 9: 698-704. PMID 2446940 DOI: 10.1093/toxsci/9.4.698  0.353
1987 Gant DB, Cole RJ, Valdes JJ, Eldefrawi ME, Eldefrawi AT. Action of tremorgenic mycotoxins on GABAA receptor. Life Sciences. 41: 2207-14. PMID 2444852 DOI: 10.1016/0024-3205(87)90517-0  0.506
1987 Eldefrawi AT, Eldefrawi ME. Receptors for gamma-aminobutyric acid and voltage-dependent chloride channels as targets for drugs and toxicants. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 1: 262-71. PMID 2443413  0.472
1986 Bakry NM, Sherby SM, Eldefrawi AT, Eldefrawi ME. Oxadiazolidinones: irreversible inhibition of cholinesterases and effects on acetylcholine receptors. Neurotoxicology. 7: 1-10. PMID 3822252  0.424
1986 Abalis IM, Eldefrawi ME, Eldefrawi AT. Effects of insecticides on GABA-induced chloride influx into rat brain microsacs. Journal of Toxicology and Environmental Health. 18: 13-23. PMID 3009836 DOI: 10.1080/15287398609530844  0.34
1986 Abalis IM, Eldefrawi AT, Eldefrawi ME. Actions of avermectin B1a on the gamma-aminobutyric acidA receptor and chloride channels in rat brain. Journal of Biochemical Toxicology. 1: 69-82. PMID 2856070  0.367
1986 Sherby SM, Eldefrawi AT, Deshpande SS, Albuquerque EX, Eldefrawi ME. Effects of pyrethroids on nicotinic acetylcholine receptor binding and function Pesticide Biochemistry and Physiology. 26: 107-115. DOI: 10.1016/0048-3575(86)90082-9  0.539
1986 Abalis IM, Eldefrawi AT. [3H]Muscimol binding to a putative GABA receptor in honey bee brain and its interaction with avermectin B1a Pesticide Biochemistry and Physiology. 25: 279-287. DOI: 10.1016/0048-3575(86)90001-5  0.381
1986 Sherby SM, Eldefrawi AT, David JA, Sattelle DB, Eldefrawi ME. Interactions of charatoxins and nereistoxin with the nicotinic acetylcholine receptors of insect cns andTorpedo electric organ Archives of Insect Biochemistry and Physiology. 3: 431-445. DOI: 10.1002/Arch.940030504  0.56
1985 Sherby SM, Eldefrawi AT, Albuquerque EX, Eldefrawi ME. Comparison of the actions of carbamate anticholinesterases on the nicotinic acetylcholine receptor. Molecular Pharmacology. 27: 343-8. PMID 3974572  0.553
1985 Filbin MT, Eldefrawi ME, Eldefrawi AT. Biochemical identification of a putative glutamate receptor in housefly thoracic membranes. Life Sciences. 36: 1531-9. PMID 2858805 DOI: 10.1016/0024-3205(85)90377-7  0.373
1985 Eldefrawi ME, Sherby SM, Abalis IM, Eldefrawi AT. Interactions of pyrethroid and cyclodiene insecticides with nicotinic acetylcholine and GABA receptors. Neurotoxicology. 6: 47-62. PMID 2410832  0.362
1985 Abalis IM, Eldefrawi ME, Eldefrawi AT. Binding of GABA receptor channel drugs to a putative voltage-dependent chloride channel in Torpedo electric organ. Biochemical Pharmacology. 34: 2579-82. PMID 2409983 DOI: 10.1016/0006-2952(85)90550-7  0.324
1985 Abalis IM, Eldefrawi ME, Eldefrawi AT. High-affinity stereospecific binding of cyclodiene insecticides and γ-hexachlorocyclohexane to γ-aminobutyric acid receptors of rat brain Pesticide Biochemistry and Physiology. 24: 95-102. DOI: 10.1016/0048-3575(85)90118-X  0.361
1985 Sattelle DB, Hue B, Pelhate M, Sherby SM, Eldefrawi AT, Eldefrawi ME. Actions of phencyclidine and its thienylpyrrolidine analogue on synaptic transmission and axonal conduction in the central nervous system of the cockroach Periplaneta americana Journal of Insect Physiology. 31: 917-924. DOI: 10.1016/0022-1910(85)90025-3  0.39
1984 El-Fakahany EE, Eldefrawi AT, Murphy DL, Aguayo LG, Triggle DJ, Albuquerque EX, Eldefrawi ME. Interactions of phencyclidine with crayfish muscle membranes. Sensitivity to calcium channel antagonists and other drugs. Molecular Pharmacology. 25: 369-78. PMID 6328263  0.34
1984 El-Fakahany EE, Triggle DJ, Eldefrawi AT, Eldefrawi ME. Distinction between high-affinity [3H]phencyclidine binding sites and muscarinic receptors in guinea-pig ileum muscle. The Journal of Pharmacology and Experimental Therapeutics. 229: 447-54. PMID 6325665  0.438
1984 Idriss MH, Filbin MT, Eldefrawi AT. Effects of chlorisondamine and philanthotoxin on the glutamate receptor/channel complex of locus muscle Federation Proceedings. 43: no. 335.  0.374
1983 Eldefrawi ME, Eldefrawi AT. Neurotransmitter receptors as targets for pesticides. Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes. 18: 65-88. PMID 6339601 DOI: 10.1080/03601238309372358  0.569
1983 Abbassy MA, Eldefrawi ME, Eldefrawi AT. Influence of the alcohol moiety of pyrethroids on their interactions with the nicotinic acetylcholine receptor. Journal of Toxicology and Environmental Health. 12: 575-90. PMID 6321746 DOI: 10.1080/15287398309530450  0.476
1983 Ei-Fakahany EF, Miller ER, Abbassy MA, Eldefrawi AT, Eldefrawi ME. Alcohol modulation of drug binding to the channel sites of the nicotinic acetylcholine receptor. The Journal of Pharmacology and Experimental Therapeutics. 224: 289-96. PMID 6296354  0.384
1983 Abalis IM, Eldefrawi ME, Eldefrawi AT. Biochemical identification of putative GABA/benzodiazepine receptors in house fly thorax muscles Pesticide Biochemistry and Physiology. 20: 39-48. DOI: 10.1016/0048-3575(83)90119-0  0.306
1983 Abbassy MA, Eldefrawi ME, Eldefrawi AT. Pyrethroid action on the nicotinic acetylcholine receptor/channel Pesticide Biochemistry and Physiology. 19: 299-308. DOI: 10.1016/0048-3575(83)90058-5  0.413
1982 Bakry NM, Eldefrawi AT, Eldefrawi ME, Riker WF. Interactions of quaternary ammonium drugs with acetylcholinesterase and acetylcholine receptor of Torpedo electric organ. Molecular Pharmacology. 22: 63-71. PMID 7121452  0.316
1982 El-Fakahany EF, Eldefrawi AT, Eldefrawi ME. Nicotinic acetylcholine receptor desensitization studied by [3H]perhydrohistrionicotoxin binding. The Journal of Pharmacology and Experimental Therapeutics. 221: 694-700. PMID 7086681  0.523
1982 Eldefrawi AT, Mansour NA, Eldefrawi ME. Insecticides affecting acetylcholine receptor interactions. Pharmacology & Therapeutics. 16: 45-65. PMID 6752971 DOI: 10.1016/0163-7258(82)90031-6  0.431
1982 Abbassy MA, Eldefrawi ME, Eldefrawi AT. Allethrin interactions with the nicotinic acetylcholine receptor channel. Life Sciences. 31: 1547-52. PMID 6292640 DOI: 10.1016/0024-3205(82)90045-5  0.5
1982 Eldefrawi AT, Miller ER, Eldefrawi ME. Binding of depolarizing drugs to the ionic channel sites of the nicotinic acetylcholine receptor. Biochemical Pharmacology. 31: 1819-22. PMID 6285933 DOI: 10.1016/0006-2952(82)90697-9  0.446
1982 Shaker N, Eldefrawi AT, Aguayo LG, Warnick JE, Albuquerque EX, Eldefrawi ME. Interactions of d-tubocurarine with the nicotinic acetylcholine receptor/channel molecule. The Journal of Pharmacology and Experimental Therapeutics. 220: 172-7. PMID 6273528  0.327
1982 Warnick JE, Maleque MA, Bakry N, Eldefrawi AT, Albuquerque EX. Structure-activity relationships of amantadine. I. Interaction of the N-alkyl analogues with the ionic channels of the nicotinic acetylcholine receptor and electrically excitable membrane. Molecular Pharmacology. 22: 82-93. PMID 6126806  0.403
1982 Eldefrawi AT, Miller ER, Murphy DL, Eldefrawi ME. [3H]Phencyclidine interactions with the nicotinic acetylcholine receptor channel and its inhibition by psychotropic, antipsychotic, opiate, antidepressant, antibiotic, antiviral, and antiarrhythmic drugs. Molecular Pharmacology. 22: 72-81. PMID 6126805  0.399
1982 El-Fakahany EF, Eldefrawi ME, Eldefrawi AT. Desensitization of torpedo nicotinic acetylcholine receptors Federation Proceedings. 41: No. 6146.  0.434
1981 Desouki A, Eldefrawi AT, Eldefrawi ME. A new mechanism revealed for the action of antibodies on acetylcholine receptor function. Experimental Neurology. 73: 440-50. PMID 7262247 DOI: 10.1016/0014-4886(81)90278-8  0.33
1981 Aronstam RS, Eldefrawi AT, Pessah IN, Daly JW, Albuquerque EX, Eldefrawi ME. Regulation of [3H]perhydrohistrionicotoxin binding to Torpedo ocellata electroplax by effectors of the acetylcholine receptor. The Journal of Biological Chemistry. 256: 2843-50. PMID 7204378  0.51
1981 Albuquerque EX, Warnick JE, Mayer RF, Eldefrawi AT, Eldefrawi ME. Recent advances in the molecular mechanisms of human and animal models of myasthenia gravis. Annals of the New York Academy of Sciences. 377: 496-518. PMID 6280564 DOI: 10.1111/J.1749-6632.1981.Tb33756.X  0.303
1981 Shaker N, Eldefrawi AT, Miller ER, Eldefrawi ME. Interaction of tricyclic antidepressants with the ionic channel of the acetylcholine receptor of Torpedo electric organ. Molecular Pharmacology. 20: 511-8. PMID 6276711  0.35
1981 Eldefrawi ME, Warnick JE, Schofield GG, Albuquerque EX, Eldefrawi AT. Interaction of imipramine with the ionic channel of the acetylcholine receptor of motor endplate and electric organ. Biochemical Pharmacology. 30: 1391-4. PMID 6268097 DOI: 10.1016/0006-2952(81)90331-2  0.303
1981 Shaker N, Eldefrawi A. Muscarinic receptor in house fly brain and its interaction with chlorobenzilate Pesticide Biochemistry and Physiology. 15: 14-20. DOI: 10.1016/0048-3575(81)90030-4  0.585
1981 Shaker N, Eldefrawi AT. [3H]ONB binding to housefly brain: Relation to muscarinic acetylcholine receptors Federation Proceedings. 40: 490.  0.465
1981 Shaker N, Eldefrawi ME, Eldefrawi AT. Interaction of imipramine (IMIP) with the ionic channel of the nicotinic acetylcholine receptor Federation Proceedings. 40: 147.  0.41
1980 Aronstam RS, Eldefrawi ME, Eldefrawi AT, Albuquerque EX, Jim KF, Triggle DJ. Sites of action of phencyclidine. III. Interactions with muscarinic receptors. Molecular Pharmacology. 18: 179-84. PMID 7421791  0.395
1980 Albuquerque EX, Tsai MC, Aronstam RS, Witkop B, Eldefrawi AT, Eldefrawi ME. Phencyclidine interactions with the ionic channel of the acetylcholine receptor and electrogenic membrane. Proceedings of the National Academy of Sciences of the United States of America. 77: 1224-8. PMID 6928673 DOI: 10.1073/Pnas.77.2.1224  0.463
1980 Eldefrawi ME, Eldefrawi AT, Aronstam RS, Maleque MA, Warnick JE, Albuquerque EX. [3H]Phencyclidine: a probe for the ionic channel of the nicotinic receptor. Proceedings of the National Academy of Sciences of the United States of America. 77: 7458-62. PMID 6261260 DOI: 10.1073/Pnas.77.12.7458  0.486
1980 Eldefrawi ME, Eldefrawi AT. Coupling between the nicotinic acetylcholine receptor site and the ionic channel site. Annals of the New York Academy of Sciences. 358: 239-52. PMID 6259991  0.384
1980 Albuquerque EX, Tsai MC, Aronstam RS, Eldefrawi AT, Eldefrawi ME. Sites of action of phencyclidine. II. Interaction with the ionic channel of the nicotinic receptor. Molecular Pharmacology. 18: 167-78. PMID 6252436  0.386
1980 Aronstam RS, Eldefrawi AT, Eldefrawi ME. Similarities in the binding sites of the muscarinic receptor and the ionic channel of the nicotinic receptor. Biochemical Pharmacology. 29: 1311-4. PMID 6249329 DOI: 10.1016/0006-2952(80)90292-0  0.534
1980 Eldefrawi AT, Bakry NM, Eldefrawi ME, Tsai MC, Albuquerque EX. Nereistoxin interaction with the acetylcholine receptor-ionic channel complex. Molecular Pharmacology. 17: 172-9. PMID 6248754  0.349
1980 Eldefrawi ME, Aronstam RS, Bakry NM, Eldefrawi AT, Albuquerque EX. Activation, inactivation, and desensitization of acetylcholine receptor channel complex detected by binding of perhydrohistrionicotoxin. Proceedings of the National Academy of Sciences of the United States of America. 77: 2309-13. PMID 6246539 DOI: 10.1073/Pnas.77.4.2309  0.453
1979 Adler M, Oliveira AC, Albuquerque EX, Mansour NA, Eldefrawi AT. Reaction of tetraethylammonium with the open and closed conformations of the acetylcholine receptor ionic channel complex. The Journal of General Physiology. 74: 129-52. PMID 486241 DOI: 10.1085/jgp.74.1.129  0.356
1979 Eldefrawi ME, Copio DS, Hudson CS, Rash J, Mansour NA, Eldefrawi AT, Albuguergue EX. Effects of antibodies to Torpedo acetylcholine receptor on the acetylcholine receptor--ionic channel complex of Torpedo electroplax and rabbit intercostal muscle. Experimental Neurology. 64: 428-44. PMID 428517 DOI: 10.1016/0014-4886(79)90281-4  0.512
1979 Eldefrawi ME, Eldefrawi AT. Biochemical studies on the ionic channel of Torpedo acetylcholine receptor. Advances in Cytopharmacology. 3: 213-23. PMID 382785  0.482
1979 Tiedt TN, Albuquerque EX, Bakry NM, Eldefrawi ME, Eldefrawi AT. Voltage- and time-dependent actions of piperocaine on the ion channel of the acetylcholine receptor. Molecular Pharmacology. 16: 909-21. PMID 316855  0.325
1979 Tsai MC, Oliveira AC, Albuquerque EX, Eldefrawi ME, Eldefrawi AT. Mode of action of quinacrine on the acetylcholine receptor ionic channel complex. Molecular Pharmacology. 16: 382-92. PMID 316101  0.327
1978 Sarvey JM, Albuquerque EX, Eldefrawi AT, Eldefrawi M. Effects of alpha-bungarotoxin and reversible cholinergic ligands on normal and denervated mammalian skeletal muscle. Membrane Biochemistry. 1: 131-57. PMID 756485 DOI: 10.3109/09687687809064163  0.318
1978 Eldefrawi ME, Eldefrawi AT, Mansour NA, Daly JW, Witkop B, Albuquerque EX. Acetylcholine receptor and ionic channel of Torpedo electroplax: binding of perhydrohistrionicotoxin to membrane and solubilized preparations. Biochemistry. 17: 5474-84. PMID 728410 DOI: 10.1021/Bi00618A023  0.428
1978 Rübsamen H, Eldefrawi AT, Eldefrawi ME, Hess GP. Characterization of calcium-binding sites of the purified acetylcholine receptor and identification of the calcium-binding subunit. Biochemistry. 17: 3818-25. PMID 698199 DOI: 10.1021/Bi00611A022  0.326
1978 Albuquerque EX, Eldefrawi AT, Eldefrawi ME, Mansour NA, Tsai MC. Amantadine: neuromuscular blockade by suppression of ionic conductance of the acetylcholine receptor. Science (New York, N.Y.). 199: 788-90. PMID 622570 DOI: 10.1126/Science.622570  0.461
1978 Tsai MC, Bakry NM, Eldefrawi AT, Albuquerque EX. Rimantadine on the ion conductance modulator of the cholinergic receptor Federation Proceedings. 37: No. 3008.  0.307
1977 Eldefrawi ME, Mansour NA, Eldefrawi AT. Interactions of acetylcholine receptors with organic mercury compounds. Advances in Experimental Medicine and Biology. 84: 449-63. PMID 899953  0.521
1977 Eldefrawi AT, Mansour NA, Brattsten LB, Ahrens VD, Lisk DJ. Further toxicologic studies with commercial and candidate flame retardant chemicals. Part II. Bulletin of Environmental Contamination and Toxicology. 17: 720-6. PMID 880389 DOI: 10.1007/BF01685960  0.323
1977 Eldefrawi AT, Eldefrawi ME, Albuquerque EX, Oliveira AC, Mansour N, Adler M, Daly JW, Brown GB, Burgermeister W, Witkop B. Perhydrohistrionicotoxin: a potential ligand for the ion conductance modulator of the acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. 74: 2172-6. PMID 301278 DOI: 10.1073/Pnas.74.5.2172  0.419
1977 Mansour NA, Elderfrawi ME, Eldefrawi AT. Isolation of putative acetylcholine receptor proteins from housefly brain. Biochemistry. 16: 4126-32. PMID 71919  0.346
1977 Mansour NA, Eldefrawi AT. Interaction of pesticides with the acetylcholine receptor Federation Proceedings. 36: No. 676.  0.422
1976 Rübsamen H, Hess GP, Eldefrawi AT, Eldefrawi ME. Interaction between calcium and ligand-binding sites of the purified acetylcholine receptor studied by use of a fluorescent lanthanide. Biochemical and Biophysical Research Communications. 68: 56-63. PMID 942851 DOI: 10.1016/0006-291X(76)90009-7  0.324
1976 Eldefrawi AT, Eldefrawi ME. Identification of a calcium-binding subunit of the acetylcholine receptor. Biochemical and Biophysical Research Communications. 70: 1020-7. PMID 938522 DOI: 10.1016/0006-291X(76)90694-X  0.376
1975 Eldefrawi ME, Eldefrawi AT, Wilson DB. Tryptophan and cystein residues of the acetylcholine receptors of Torpedo species. Relationship to binding of cholinergic ligands. Biochemistry. 14: 4304-10. PMID 1182102  0.439
1975 Edelstein SJ, Beyer WB, Eldefrawi AT, Eldefrawi ME. Molecular weight of the acetylcholine receptors of electric organs and the effect of Triton X 100 Journal of Biological Chemistry. 250: 6101-6106. PMID 1150674  0.385
1975 Eldefrawi ME, Eldefrawi AT, Penfield LA, O'Brien RD, Van Campen D. Binding of calcium and zinc to the acetylcholine receptor purified from Torpedo Californica Life Sciences. 16: 925-935. PMID 1128162 DOI: 10.1016/0024-3205(75)90008-9  0.391
1973 Eldefrawi ME, Eldefrawi AT. Purification and molecular properties of the acetylcholine receptor from Torpedo electroplax. Archives of Biochemistry and Biophysics. 159: 362-73. PMID 4806354 DOI: 10.1016/0003-9861(73)90462-1  0.416
1973 Eldefrawi ME, Eldefrawi AT. Cooperativities in the binding of acetylcholine to its receptor. Biochemical Pharmacology. 22: 3145-50. PMID 4761574 DOI: 10.1016/0006-2952(73)90209-8  0.523
1972 Eldefrawi ME, Eldefrawi AT, Seifert S, O'Brien RD. Properties of lubrol-solubilized acetylcholine receptor from Torpedo electroplax. Archives of Biochemistry and Biophysics. 150: 210-8. PMID 5028075 DOI: 10.1016/0003-9861(72)90028-8  0.456
1972 Eldefrawi ME, Eldefrawi AT. Characterization and partial purification of the acetylcholine receptor from Torpedo electroplax. Proceedings of the National Academy of Sciences of the United States of America. 69: 1776-80. PMID 4505655  0.444
1972 O'Brien RD, Eldefrawi ME, Eldefrawi AT. Isolation of acetylcholine receptors. Annual Review of Pharmacology. 12: 19-34. PMID 4339017 DOI: 10.1146/annurev.pa.12.040172.000315  0.431
1971 Eldefrawi ME, Britten AG, Eldefrawi AT. Acetylcholine binding to Torpedo electroplax: relationship to acetylcholine receptors. Science (New York, N.Y.). 173: 338-40. PMID 5559905  0.494
1971 Eldefrawi ME, Eldefrawi AT, O'Brien RD. Binding of five cholinergic ligands to housefly brain and Torpedo electroplax. Relationship to acetylcholine receptors. Molecular Pharmacology. 7: 104-10. PMID 5552246  0.432
1971 Eldefrawi ME, Eldefrawi AT, O'Brien RD. Binding sites for cholinergic ligands in a particulate fraction of Electrophorus electroplax. Proceedings of the National Academy of Sciences of the United States of America. 68: 1047-50. PMID 4102561  0.411
1970 Eldefrawi AT, O'Brien RD. Binding of muscarone by extracts of housefly brain: relationship to receptors for acetylcholine. Journal of Neurochemistry. 17: 1287-93. PMID 5457631  0.398
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